Gene TAF1 (Mouse)

TAF1

Species: Mouse
Alias: B430306D02Rik, TAF1
External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , iHOP
Annotation:

Classification

Group: Atypical
Family: TAF1

Sequence

Name Sequence Type Origin Length Description Download
TAF1.NA RNA Sugen 6653 None Fasta, JSON
TAF1.AA Protein Sugen 1923 None Fasta, JSON

Protein domain

Protein domains of TAF1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
TBP-binding TAF1.AA TBP-binding 22-87 42 1.3e-32 113.69 Pfam 1-77 (77) Show / Hide 
Range on Protein: 22-87
Range on HMM: 1-77/77
Sequence Identity: 42% (33 aa)

SDTDSDEESAGGGPFSLTGFLFGNINGAGQLEGESV----LDDECKKHLAGLGALGLGSLITEL--------TANEEL
|| |.|.|.  ...|.|||||||||...||||....    ||.|||.||..|...||||...|.        |.... 
SDDDNDNERN-SRGFNLTGFLFGNIDEHGQLEDDDFREQGLDEECKEHLSSLSKMGLGSMLHEVNLLAKSERTDSDDA
DUF3591 TAF1.AA DUF3591 613-1076 40 1.7e-253 853.21 Pfam 1-494 (494) Show / Hide 
Range on Protein: 613-1076
Range on HMM: 1-494/494
Sequence Identity: 40% (200 aa)

WNL--SNDEYYYPKQQ----GLRGTFGGNIIQHSIPAVELRQPFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSV--QPLLKHIKKKAKMREQERQA
.|.  |||||| ....      | |.|.. |.||.||..|..|...........|.||||....|.     .|| . .  .  |||.|.|...||.||..
FNIIFSNDEYYDMLKENHQNKVRQTIGNLNIEHSMPALRLQWPYYKVKLNKREARSFHRPHFQFYI-----RPGTQIWVRFSKLKHRKRKHDKREKERMG

SGGGEMFFMRTPQDLTGKD-GDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCK-YGETVYCHT---SPF--LGSLHPGQLLQAFENNLFR
....|.|.|||..|||..| ...||.||.||. |.|...||..||.|||..| ..|.. |... .||| ..|.   |||  .|..|||.  .. .||..|
KDISEVFKMRTTKDLTLGDNSPVILMEYCEEYPPVMSNFGMGSKIINYYRKKHMEDTHRPKLDDIGETHVLHPQDKSPFWNFGHVHPGEIVPTLYNNMYR

APIYLHKMPESDFLIIRTRQ------GYFIRELVDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAF-PSHSESSI
|||. ||... |||.||...       |..|.  ..|.|||..|..|||||.|..........|....|||||..|....||...||.|.| | ..|...
APIFKHKPEPTDFLCIRSTTPGGHGQKYYLRNIDHMFCVGQTFPVMEVPGPHSRKVTNMSKNRLKMIVYRLFWGQKSPRHRISIHDITKHFFPDQNEMQN

RKRLKLCADFKRTG-MD-SNWWVLKSDFRLPTE-EEIRAMVSPEQCCAYYSMIAAEQRLKDAGYGEKSFFAP-----EEENEEDF---QMKIDDEVRTAP
|.||| .....|.| || ..||.||....||.| ||||.|..||.||.|.||....|.|.||||.....|..      |...|..   |||||.|...||
RQRLKEFMKYQRDGGMDNQGWWKLKEGETLPDEFEEIRKMITPEDCCLYESMQVGQQHLEDAGYNNTDEFKRDYQQIQEDDDEETKKVQMKIDLEQMMAP

WNTTRAFIAAMKGKCLLEVTGVADPTGCGEGFSYVKI-PNKPT--QQKDDKEPQPVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKLSRWEVIDV
|||||.|| |..||..|.. |..||||||||||.... ..|..  .|.......| ||.|.||.|..|.....|..|..|..|||||||.....|.....
WNTTRNFINATQGKAMLQLHGEGDPTGCGEGFSFIRTKSMKGGFLKQGEGPQDKP-KKAVAGTRAKERGGHSYNVAQQQRLYGVPEEEIRRIWYWQKRSL
DUF3591 TAF1.AA DUF3591 1103-1125 38 6.463577 0.29 Pfam 469-494 (494) Show / Hide 
Range on Protein: 1103-1125
Range on HMM: 469-494/494
Sequence Identity: 38% (10 aa)

VAEHQERY---KEECQRIFDLQNKVL
||. |. |    ||  || . | . |
VAQQQRLYGVPEEEIRRIWYWQKRSL
BROMO TAF1.AA BROMO 1431-1539 26 2.4e-34 121.35 SMART 1-118 (118) Show / Hide 
Range on Protein: 1431-1539
Range on HMM: 1-118/118
Sequence Identity: 26% (32 aa)

RTDPMVTLSSILESIINDMRDL--------PNTYPFHTPVNAKV--VKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLT
. . .  ....|..... ..|         | ..||. ||..|   . |||.||..||||.| ....... | |.||| . ..|...|  |||.| ..  
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNEPDSEVY

QISQSMLDLCDEKLKEKED
. .. . ... ||..| ..
KMAKKLQKFFEEKWREFPP
Bromodomain TAF1.AA Bromodomain 1442-1525 30 1.1e-25 86.12 Pfam 1-89 (89) Show / Hide 
Range on Protein: 1442-1525
Range on HMM: 1-89/89
Sequence Identity: 30% (27 aa)

LESIIN--DMRDLPNTYPFHTPV--NAKVVKDYYKIITRPMDLQTLRENVRKRLYP-SREEFREHLELIVKNSATYNGPKHSLTQISQS
.. |..  .. . |.. ||. ||  . ... |||.||..||||.| ..... . |  . .||....||. .|. |||||.. . .... 
CDQIMDMKYIMEHPICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK
BROMO TAF1.AA BROMO 1553-1662 33 5.6e-42 146.69 SMART 1-118 (118) Show / Hide 
Range on Protein: 1553-1662
Range on HMM: 1-118/118
Sequence Identity: 33% (40 aa)

DDDDQVAFSFILDNIVTQKMMA-------VPDSWPFHHPVNKKF--VPDYYKVIVSPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYT
| . |  ....|. .. .|.         .|..|||..||..|   .||||..|  ||||.||.|.. .|.|||.|.|.||..|.. |  .||.|.|.. 
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNEPDSEVY

KTAQEIVNVCHQTLTEYDE
| |... ... ....|. .
KMAKKLQKFFEEKWREFPP
Bromodomain TAF1.AA Bromodomain 1564-1648 37 1.8e-29 98.47 Pfam 1-89 (89) Show / Hide 
Range on Protein: 1564-1648
Range on HMM: 1-89/89
Sequence Identity: 37% (33 aa)

LDNIVT-QKMMAVPDSWPFHHPV--NKKFVPDYYKVIVSPMDLETIRKNISKHKYQ-SRESFLDDVNLILANSVKYNGPESQYTKTAQE
.|.|.. ...|  |...||.|||  ... .||||..|  ||||.||....  .||. . . |. |..|.. |...||||.|.. | |..
CDQIMDMKYIMEHPICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK