Gene F16B12.5 (Nematode worm)

F16B12.5

Species: Nematode worm
Alias: F16B12.5, aSWK115, CE09428
External Links: Wormbase Link ,
Annotation: WormBase Physical Map location: X: 14103406-14105183, WormBase Genetic Map location: X:15.72,

Classification

Group: CK1
Family: CK1-Unique

Sequence

Name Sequence Type Origin Length Description Download
F16B12.5.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 287 Kinase domain by global Sugen HMM Fasta, JSON
F16B12.5.AA Protein Genbank 394 None Fasta, JSON

Protein domain

Protein domains of F16B12.5.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase F16B12.5.AA CK1-Unique 74-352 27 8.20000000001e-151 507.32 In-house 1-337 (337) Show / Hide 
Range on Protein: 74-352
Range on HMM: 1-337/337
Sequence Identity: 27% (91 aa)

VIIIKKFPAGKF--VKRVDFVNRGTIRSSSDMHCGSGIQIAIRRTEQNATILQLDLLGLNLLEYAELYGGKLEVPEAFHLARQMIDLLHTIHDRGIVHCD
...||....|..  |.||.|||.||.|...||.|....|.......|...|...........||...|.........||..|.......|.|......|.
WCVIKHIGYGGYGCVHRVIFVNNGTFRIDDDMYCMKTEQHFMQKHDQRLHIERNVMKFICKCEYQCKYWRHFCEVHDFHQHRDWWWIVMTMHGPSMEECC

IKPANFAFGLNEKKNQLNLIDFGLAESFLDDRGNHREVHNRHYRKGTYVYMSANQHHEQCFGKSFLFAFVSALLIENSAFSKKILLTIPRRKVKPNIFCS
....||.|.||||||||..|..|...............|.||.....|.||...|.|..|................|...........|.|..|....||
MMMKNFQFTLNEKKNQLCAIQCGYQCLNVIECMHWHGFHHRHMKPNNYCYMAPSQQHQHCYYMLDYGICRRVFFVSNNHQIRQPRPITPFRGCKDYCPCS

NYLITGNTRRDDMESLVYSLRKILDLT--------------------------------------------------------MCWKEGRSVNNDDTHRN
........|||||||..|.|......|                                                        ||||..|..|..|.|.|
CHQCREHGRRDDMESWFYMLYHLVHNTRGLSWKLDKIIPSGIDNIIVYLRGLKFEDPVDYRQIENELRTAGKKMAPSDSSDEKMCWKGLRRQNAYDKHKN

YFNLKQGNQKSCSLCGIQPINDMLQSCRMLEFKDEPN
|.|.||.|.|.|..|.|.|.|||...|.|.|.....|
YQNSKQFNEKPCLFCKIKPHNDMKMYCCMSEYFYMFN
Kinase F16B12.5.AA CK1 115-227 27 1.4e-28 96.8 In-house 98-243 (339) Show / Hide 
Range on Protein: 115-227
Range on HMM: 98-243/339
Sequence Identity: 27% (40 aa)

RTEQNATILQLDLLGLNLLEYAE---LYGGKLEVPEAFHLARQMIDLLHTIHDRGIVHCDIKPANFAFGL-------------NEKKNQLNLIDFGLAE-
.....  .. ..||| || .. .   . ..|. .. ....| ||.. |  .||.|..| ||||.||..|.             |....|. .||||.|  
EEDDYYNYMVMTLLGPNLEDLRKQNRMCNRKFSMKTWLMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARR

SFLDDRGNHREVHN---------RHYRK--------G-TYVYMSANQH
 ..|..|..|  .|         | .|.        | |  |.| | |
KYRDKDGHNR--WNGPRDKTWQHRPPREHKKKKGFRGCTARYCSINCH
Kinase F16B12.5.AA CK1-Unclassified 151-206 38 8.1e-18 49.18 In-house 109-167 (244) Show / Hide 
Range on Protein: 151-206
Range on HMM: 109-167/244
Sequence Identity: 38% (23 aa)

LARQMIDLLHTIHDRGIVHCDIKPANFAFG-LNEKKNQLNLIDFGLAESFL--DDRGNH
.| |||. .  .| ....| |||| ||  | |. ...|. .|||||.  ..  |  |.|
IADQMIQRIEYLHNKNFIHRDIKPDNFLMGKLGKNHHQVYIIDFGLSKRYIDMDKTGKH
Kinase F16B12.5.AA CK1 151-206 39 1.1e-17 57.59 In-house 110-167 (271) Show / Hide 
Range on Protein: 151-206
Range on HMM: 110-167/271
Sequence Identity: 39% (23 aa)

LARQMIDLLHTIHDRGIVHCDIKPANFAFGL-NEKKNQLNLIDFGLAESFLDDR-GNH
.| |||. .  .| ....| |||| ||  |. . ...|. .||||||  ..||. ..|
IADQMIQRIEYVHNKNFIHRDIKPDNFLMGRYGKHCHQVYIIDFGLAKRYRDDKTHQH
Kinase F16B12.5.AA CK1-A 116-227 33 5.7e-15 49.18 In-house 65-177 (261) Show / Hide 
Range on Protein: 116-227
Range on HMM: 65-177/261
Sequence Identity: 33% (38 aa)

TEQNATILQLDLLGLNLLEYAELYGGKLEVPEAFHLARQMIDLLHTIHDRGIVHCDIKPANFAFGLNEKKNQLNLIDFGLAESFLDDRG-NHREVHNRHY
.|..  .. .||||  | .   .   .  .     || |||  .  .| .. .| |||| ||  |..   |.| |||||||  . | |   | . .. . 
CEKDYNVMVMDLLGPSLEDLFNFCKRRFTMKTVLMLADQMIMRIEYVHEKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDSRTRQHIPYREDKN

RKGTYVYMSANQH
  ||  | | | |
LTGTARYASINAH
Kinase F16B12.5.AA CK1 279-356 21 8.6e-14 44.56 In-house 249-339 (339) Show / Hide 
Range on Protein: 279-356
Range on HMM: 249-339/339
Sequence Identity: 21% (20 aa)

TRRDDMESLVYSLRKILDLT--MCWKEGRSVNN------DDTHRNYFNLKQGNQKSCSLCGI-------QPINDMLQSCRMLEFKDEPNYEAV
.||||..|. | |   |. |  . |.  .. ..       . ...... |  ..... ||         |   .... .| |...|.|.||..
GRRDDLWSWFYMLIEWLKGTPGLPWQNMKDEMKPKDHQVEKMKYEFIDEKKMSTPFF-LCCPKKDHDCPQEF-KIMKYIRSLKYYDRPDYEMI
Kinase F16B12.5.AA Worm8 149-205 36 3.6e-13 34.38 In-house 102-158 (261) Show / Hide 
Range on Protein: 149-205
Range on HMM: 102-158/261
Sequence Identity: 36% (21 aa)

FHLARQMIDLLHTIHDRGIVHCDIKPANFAFGLNEKKNQLNLIDFGLAESFLDDRGN
..   |..  |  ||  |||| |||. |       .  .| |.|||.. .| |  ||
YQIMWQLVKILQDIHSFGIVHGDIKADNLMVSHSNRMFMLVLVDFGCSCWFKDHNGN
Kinase F16B12.5.AA Dual 141-207 32 8.2e-13 39.28 In-house 108-175 (282) Show / Hide 
Range on Protein: 141-207
Range on HMM: 108-175/282
Sequence Identity: 32% (22 aa)

GKLEVPEAFHLARQMIDLLHTIHDRGIVHCDIKPANFAFGLNEKKNQLNLIDFGLAESFLD-DRGNHR
| | .. .|  | ||.. .   |  | .| .||||||. ||...   . . ||... ...|   . ||
GQLSMHCSFNVAIQMLRAIQDLHSIGYLHRNIKPANFHCGLGMDETTVYMQDFRIVRKYIDPENKKHR
Kinase F16B12.5.AA CK1-D 151-227 42 3e-12 39.36 In-house 100-177 (261) Show / Hide 
Range on Protein: 151-227
Range on HMM: 100-177/261
Sequence Identity: 42% (33 aa)

LARQMIDLLHTIHDRGIVHCDIKPANFAFGLNEKKNQLNLIDFGLAESFLDDR-GNHREVHNRHYRKGTYVYMSANQH
|| |||  .. || |  .| |||| ||  ||  . |  ..||||||  . | |   |          ||  | | | |
LADQMICRIEYIHCRNFIHRDIKPDNFLMGLGKRGNMVYIIDFGLAKRYRDARTHQHIPYRENKNLTGTARYASINTH
Kinase F16B12.5.AA TTBK 141-233 31 9.4e-12 37.85 In-house 92-185 (257) Show / Hide 
Range on Protein: 141-233
Range on HMM: 92-185/257
Sequence Identity: 31% (30 aa)

GKLEVPEAFHLARQMIDLLHTIHDRGIVHCDIKPANFAFGLN-EKKNQLNLIDFGLAESFLDDRGNHREVHNRHYRKGTYVYMSANQHHEQCFG
|.  .  .  |  |... .  ||. |  | |||| ||| |.| .. ..  ..|||||  ..   |. |   .     ||  | | | |  .  |
GCFSLSTTLRLGVQILQSIESIHSVGFLHRDIKPSNFAMGRNPSTCRKCYMLDFGLARQYTNACGEVRPPREVAGFRGTVRYASINAHRNREMG
Kinase F16B12.5.AA TTBKL 162-205 33 5e-10 30.13 In-house 118-165 (288) Show / Hide 
Range on Protein: 162-205
Range on HMM: 118-165/288
Sequence Identity: 33% (16 aa)

IHDRGIVHCDIKPANFAFGLNEK----KNQLNLIDFGLAESFLDDRGN
.|| |..| |.||.|...|....       . |||||.|  .... |.
MHDCGFIHRDVKPCNCCWGYHDHSCERCRHVYLIDFGMARQYAWKDGE
Kinase F16B12.5.AA Pkinase 133-223 23 2.2e-08 30.76 Pfam 79-179 (293) Show / Hide 
Range on Protein: 133-223
Range on HMM: 79-179/293
Sequence Identity: 23% (26 aa)

LEYA-------ELY-------GGKL--EVPEAFHLARQMIDLLHTIHDRGIVHCDIKPANFAFGLNEKKNQL----NLIDFGLAESFLDDRGNHREVHNR
.||.       .|.       .|..  .  |. . ..|..  |  .|..||.|.|.||.|.   |  .....     ..|||||. |      .   .  
MEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENI---LIDNNGHIDACVKICDFGLAKQFD-----Y-NNS-M

HYRKGTYVYMS
. . ||. ||.
TTFCGTPWYMA
S_TKc F16B12.5.AA S_TKc 66-317 12 3e-06 -85.6 SMART 1-231 (231) Show / Hide 
Range on Protein: 66-317
Range on HMM: 1-231/231
Sequence Identity: 12% (38 aa)

YMTIITV------FVIIIKKFP-----AGKFVKRVDFVNRGTIRSSSDMHCGSGIQIAIRRTEQNATILQLDLLGL---NLLEYAELYGGK-----LEVP
|  . ..       |   ..       | | .|  . . |     ..  |.   ...     . .   . .....    .|..| . .|..     .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-

EAFHLARQMIDLLHTIHDRGIVHCDIKPANFAFGLNEKKNQLNLIDFGLAESFLDDRGNHREVHNRHYRKGTYVYMSANQHHEQCFGK------------
.| ....|... |  .|..||.|.|.||.|  .       .. ..|||||  .             .   ||  ||.        .||            
HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL-------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

------SFLFAFVSALLIENSAFSKKILLTIPRRKVKPNIFCSNYLITGNTRRDDMESLVYSLRKILDLTMCWKEG-RSVNNDDTH-------RNYF
        .|        .  .  |||.                                 ... ...  ...    |    .  .         .|
YEMLCGYPPFP-------QMQMMFKKIG-------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase F16B12.5.AA CK1 339-354 43 0.000214 11.27 In-house 256-271 (271) Show / Hide 
Range on Protein: 339-354
Range on HMM: 256-271/271
Sequence Identity: 43% (7 aa)

LQSCRMLEFKDEPNYE
|. || |.|...|.|.
LNYCRQLHFEEKPDYM
Kinase F16B12.5.AA CK1-D 280-356 27 0.009336 5.36 In-house 184-261 (261) Show / Hide 
Range on Protein: 280-356
Range on HMM: 184-261/261
Sequence Identity: 27% (22 aa)

RRDDMESLVYSLRKILDLTMCWKEGRSVNNDDTHRNYFNLKQGNQKSCSLCGIQPIN--DMLQSCRMLEFKDEPNYEAV
||||.||| | |      .. |.  . ..  .      . |. . |   ||   | .  . .  || |.| | |.|  .
RRDDLESLGYVLMYFNRGSLPWQGLKAATKRQKYERICE-KKMSTKIDTLCKGYPSEFQQYMNYCRNLKFDDKPDYCYL
Kinase F16B12.5.AA TTBKL 345-360 37 0.015043 4.51 In-house 273-288 (288) Show / Hide 
Range on Protein: 345-360
Range on HMM: 273-288/288
Sequence Identity: 37% (6 aa)

LEFKDEPNYEAVKQLF
|...|.|.|| . ..|
LRYYDRPDYEMIYECF
Kinase F16B12.5.AA CK1-A 279-356 25 0.031261 3.48 In-house 183-261 (261) Show / Hide 
Range on Protein: 279-356
Range on HMM: 183-261/261
Sequence Identity: 25% (20 aa)

TRRDDMESLVYSLRKILDLTMCWKEGRSVNNDDTHRNYFNLKQGNQKSCSLCGIQP--INDMLQSCRMLEFKDEPNYEAV
.|||||||. | .      .. |. |   ..          |.       ||   |     ... || | |...|.|  .
SRRDDMESMGYVMMYFNRGKLPWQ-GMKAMTKKQKYEKISEKKMSTPIEQLCKGFPAEFCMYMNYCRNLRFEEQPDYMYL
Kinase F16B12.5.AA CK1-Unclassified 280-289 80 0.042444 2.01 In-house 195-204 (244) Show / Hide 
Range on Protein: 280-289
Range on HMM: 195-204/244
Sequence Identity: 80% (8 aa)

RRDDMESLVY
||||.||| |
RRDDLESLGY
Kinase F16B12.5.AA CK1 280-289 90 0.083161 2.24 In-house 195-204 (271) Show / Hide 
Range on Protein: 280-289
Range on HMM: 195-204/271
Sequence Identity: 90% (9 aa)

RRDDMESLVY
|||||||| |
RRDDMESLGY