RIO1

Species: Bakers Yeast
Alias: RIO1
External Links: Saccharomyces Genome Database Link ,
Annotation:

Classification

Group: Atypical
Family: RIO
Subfamily: RIO1

Sequence

Name Sequence Type Origin Length Description Download
RIO1.kin_dom Protein Kinase Domain Sugen global kinase HMM prediction 292 Kinase domain by global Sugen HMM Fasta, JSON
RIO1.AA Protein Refseq_NP 484 similar to a C.elegans ZK632.3 protein; Rio1p [Saccharomyces cerevisiae] Fasta, JSON

Protein domain

Protein domains of RIO1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RIO1.AA RIO1 101-301 62 1.2e-168 566.62 In-house 1-225 (225) Show / Hide
Range on Protein: 101-301
Range on HMM: 1-225/225
Sequence Identity: 62% (143 aa)

PVID--------------------------EETGQYEVLETDGSRAEYAIKIYKTSILVFKDRERYVDGEFRFRNSRSQHNPRKMIKIWAEKEFRNLKRI
.|||                          .||..|...||.|.||||||||||||||||||||.|||||||||.....||||||||||||||.||||||
QVIDPRTRMILFKMLTRGIITEINGCISTGKETNVYHASETNGKRAEYAIKIYKTSILVFKDREKYVDGEFRFRHGHCKHNPRKMIKIWAEKEMRNLKRI

YQSGVIPAPKPIEVKNNVLVMEFLSRGNGFASPKLKDYPYKNRDEIFHYYHTMVAYMRLLYQVCRLVHADLSEYNTIVHDDKLYMIDVSQSVEPEHPMSL
||| .||.|.||.||.|||.|||... .|.|.|.||||.||.||..|||||.|..|||..||.||||||||||||...|.|||||||||||||..||.||
YQS-EIPCPEPIMVKSNVLMMEFIGK-DGMAAPRLKDYQYKERDQYFHYYHQMIQYMRRMYQDCRLVHADLSEYNMLYHNDKLYMIDVSQSVEHDHPHSL

DFLRMDIKNVNLYFEKMGISIFPERVI
.|||||.||||.||.|....|||.|.|
EFLRMDCKNVNMYFMKHNVIIFPVRDI

RIO RIO1.AA RIO 47-307 44 2.2e-143 483.54 SMART 1-253 (253) Show / Hide
Range on Protein: 47-307
Range on HMM: 1-253/253
Sequence Identity: 44% (120 aa)

DKANRATVENVLDPRTMRFLKSMVTRGVIADLN--GCLSTGKEANVYHAFAGTGKAPVIDEETGQYEVLETDGSRAEYAIKIYKTSILVFKDRERYVDGE
||...||.|.|.||||...|..||.||.|...|  ||.|||||||||||..|                 ..|... |.|.|||.||...||...||..|.
DKEDYATYEEVFDPRTRMTLYKMVNRGYIEEINNHGCISTGKEANVYHAMGG-----------------DFDKNGNECAVKIYRTSTTEFKRMWRYIQGD

FRFRNSRSQHNPRKMIKIWAEKEFRNLKRIYQSGVIPAPKPIEVKNNVLVMEFLSRGNGFASPKLKDYPYKNRDEIF--HYYHTMVAYMRLLYQVCRLVH
|||.......|.|||...|||||||||.|.|.. ..|.||||.....||||||... .|.. |.|||.........|  .||.... ||| .|..|.|||
FRFKHGYHHINWRKMVRLWAEKEFRNLQRMYEA-GVPCPKPIAWRRHVLVMEFIGD-DGWPAPRLKDVEWEEWEMDFKWEYYWQIMEYMRKMYHECHLVH

ADLSEYNTIVH------DDKLYMIDVSQSVEPEHPMSLDFLRMDIKNVNLYFEKMGISIFP-ERVIFQFVIS
|||||||...|      |.|...||.|||||..|||.|.||..||.|.. .|...|.. .. .|.||.....
ADLSEYNMLYHDLEDENDCKVWIIDWSQSVECDHPMWLEFLERDIWNIINFFRRKGVDCDDIYREIFERITG

Kinase RIO1.AA RIO 101-315 37 8.10000000001e-136 457.51 In-house 29-276 (276) Show / Hide
Range on Protein: 101-315
Range on HMM: 29-276/276
Sequence Identity: 37% (94 aa)

PVIDEETGQYEVLETDGSR---------AEYAIKIYKTSILVFKDRERYVDGEFRFRNSRSQHNPRKMIKIWAEKEFRNLKRIYQSGVIPAPKPIEVKNN
.....|...|......|..         .|.||||..|....||||..|.||||.|......||.|.|...|||||.||.||.||| ..|.|.||..|..
IGVGKESDIYHCSNENGEDEKEDSKVIPTECAIKIHRTGRTSFKDRKKYRDGEFYFKHRHCKHNWRYMHRLWAEKEMRNMKRLYQS-GFPCPEPIDYKRH

VLVMEFLSRGNGFASPKLKDYPYKNRDEIFHYYHTMVAYMRLLYQVCRLVHADLSEYNTIVHDDKL-------YMIDVSQSVEPEHPMSLDFLRMDIKNV
||||||... .....||.............|.||....||| |||.|||||.|..|.|...||.|.       ||||..|.||..||..|...|.|.|.|
VLVMEFINH-DQMPAPKYPMCQIHEHENMKHVYHQCMCYMRRLYQHCRLVHCDFNEFNMMWHDGKHDENDCGFYMIDFPQMVEHDHPHALWYFRRDCKCV

NLYFEKMGI-SIFPERVIFQFV------------------ISETLEKFKG
|..|.|... ..||||..|.||                  ...||.....
NMFFMKRFVYEPFPEREMFDFVGFGDGYKYAYPDFKRDVKRTDTLDHENM

Kinase RIO1.AA RIO1 89-301 42 9.1e-115 358.37 Pfam 1-200 (200) Show / Hide
Range on Protein: 89-301
Range on HMM: 1-200/200
Sequence Identity: 42% (93 aa)

NVYHAFA-GTGKAPVIDEETGQYEVLETDGSRAEYAIKIYKTSILVFKDRERYVDGEFRFRNSRSQHNPRKMIKIWAEKEFRNLKRIYQSGVIPAPKPIE
||||| .   ||.                    |.|.|||.|....||...||.|..||||. ...||.|.|...|||||||||||.|. | .|.||||.
NVYHAYSMEDGKD--------------------ECAVKIYRTGTTCFKKMKRYRDYDFRFRHRYHHHNWRYMVRMWAEKEFRNLKRMYEAG-VPCPKPID

VKNNVLVMEFLSRGNGFASPKLKDYPYKNR---DEIFHYYHTMVA-YMRLLYQVCRLVHADLSEYNTIVHDD-KLYMIDVSQSVEPEHPMSLDFLRMDIK
....||||||... .| . |.|||......   .|. ..|. ..  ||| .|| |.|||.||||||..|||| |...||..|.||. ||..|.||..|..
WNRHVLVMEFIGDKDGWPAPRLKDVEMELELSEEEAEEIYDEIIREYMRRMYQECGLVHGDLSEYNILVHDDGKPWIIDWPQAVEHDHPHALEFLERDCR

NVNLYFEKMGIS--IFPERVI
|.. .|...|..  .. .|.|
NIINFFRRKGVDERVMDFREI

Kinase RIO1.AA RIO3 51-293 40 7.4e-59 196.88 In-house 1-230 (254) Show / Hide
Range on Protein: 51-293
Range on HMM: 1-230/254
Sequence Identity: 40% (99 aa)

RATVENVLDPRTMRFLKSMVTRGVIADLNGCLSTGKEANVYHAFAGTGKAPVIDEETGQYEVLETDGSRAEYAIKIYKTSILVFKDRERYVDGEFRFRNS
 .| |  .||.|  ..  ||  |..  . ||..||||. |.||. |.     ...|  .  |. |     . |||..||..  ||.|..|.  .|||.. 
HSTAEKAVDPKTRLLMYKMVNSGMLETITGCIATGKESVVFHAYGGS-----MEDEKEDSKVIPT-----ICAIKVFKTTLNEFKNRDKYIKDDFRFKDR

RSQHNPRKMIKIWAEKEFRNLKRIYQSGVIPAPKPIEVKNNVLVMEFLSRGNGFASPKLKDYPYKNRDEIFHYYHTMVAYMRLLYQVCRLVHADLSEYNT
 |. ||||. ..|||||  || |. ..| || |  . .|  .||| |.   .   .||||.    | .|.   |.  .  || ||  | |||||||||| 
FSKLNPRKIHRMWAEKEMHNLARMQRAG-IPCPTVVLLKKHILVMSFIGH-DQVPAPKLKEVKL-NSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNM

IVHDDKLYMIDVSQSVEPEHPMSLDFLRMDIKNVNLYFEKMGI
. |  |...||||||||| ||  |.||  | .||  .|.| |.
LWHAGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGV

Kinase RIO1.AA RIO1 56-99 59 2.8e-18 59.88 In-house 1-44 (225) Show / Hide
Range on Protein: 56-99
Range on HMM: 1-44/225
Sequence Identity: 59% (26 aa)

NVLDPRTMRFLKSMVTRGVIADLNGCLSTGKEANVYHAFAGTGK
 |.||||   |  |.|||.| ..|||.|||||.|||||    ||
QVIDPRTRMILFKMLTRGIITEINGCISTGKETNVYHASETNGK

Kinase RIO1.AA RIO 54-99 32 7e-16 50.93 In-house 1-46 (276) Show / Hide
Range on Protein: 54-99
Range on HMM: 1-46/276
Sequence Identity: 32% (15 aa)

VENVLDPRTMRFLKSMVTRGVIADLNGCLSTGKEANVYHAFAGTGK
.| ..||.|   .. ||.||..   ..| ..|||...||.  . |.
YEQTNDPYTRMIMYKMVNRGMVESVGNCIGVGKESDIYHCSNENGE