Gene TAF1 (Human)

TAF1

Species: Human
Alias: BA2R, TAF1, TAF2A, OF, NSCL2, P250, TAFII250, CCGS, CCG1
External Links: iHOP , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , GeneCards
Annotation: Consensus chromosomal location: Xq13.1,

Classification

Group: Atypical
Family: TAF1

Sequence

Name Sequence Type Origin Length Description Download
TAF1.NA RNA Sugen Kinome 7709 None Fasta, JSON
TAF1.AA Protein Sugen Kinome 1893 None Fasta, JSON

Protein domain

Protein domains of TAF1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
TBP-binding TAF1.AA TBP-binding 22-87 39 3.9e-32 112.03 Pfam 1-77 (77) Show / Hide 
Range on Protein: 22-87
Range on HMM: 1-77/77
Sequence Identity: 39% (31 aa)

SDTDSDEDSAGGGPFSLAGFLFGNINGAGQLEGESV----LDDECKKHLAGLGALGLGSLITEL--------TANEEL
|| |.|...  ...|.|.|||||||...||||....    ||.|||.||..|...||||...|.        |.... 
SDDDNDNERN-SRGFNLTGFLFGNIDEHGQLEDDDFREQGLDEECKEHLSSLSKMGLGSMLHEVNLLAKSERTDSDDA
DUF3591 TAF1.AA DUF3591 586-1049 40 3.8e-256 862.01 Pfam 1-494 (494) Show / Hide 
Range on Protein: 586-1049
Range on HMM: 1-494/494
Sequence Identity: 40% (202 aa)

WNL--SNDEYYYPKQQ----GLRGTFGGNIIQHSIPAVELRQPFFPTHMGPIKLRQFHRPPLKKYSFGALSQPGPHSV--QPLLKHIKKKAKMREQERQA
.|.  |||||| ....      | |.|.. |.||.||..|..|...........|.||||....|.     .|| . .  .  |||.|.|...||.||..
FNIIFSNDEYYDMLKENHQNKVRQTIGNLNIEHSMPALRLQWPYYKVKLNKREARSFHRPHFQFYI-----RPGTQIWVRFSKLKHRKRKHDKREKERMG

SGGGEMFFMRTPQDLTGKD-GDLILAEYSEENGPLMMQVGMATKIKNYYKRKPGKDPGAPDCK-YGETVYCHT---SPF--LGSLHPGQLLQAFENNLFR
....|.|.|||..|||..| ...||.||.||. |.|...||..||.|||..| ..|.. |... .||| ..|.   |||  .|..|||.  .. .||..|
KDISEVFKMRTTKDLTLGDNSPVILMEYCEEYPPVMSNFGMGSKIINYYRKKHMEDTHRPKLDDIGETHVLHPQDKSPFWNFGHVHPGEIVPTLYNNMYR

APIYLHKMPETDFLIIRTRQ------GYYIRELVDIFVVGQQCPLFEVPGPNSKRANTHIRDFLQVFIYRLFWKSKDRPRRIRMEDIKKAF-PSHSESSI
|||. ||...||||.||...       ||.|.  ..|.|||..|..|||||.|..........|....|||||..|....||...||.|.| | ..|...
APIFKHKPEPTDFLCIRSTTPGGHGQKYYLRNIDHMFCVGQTFPVMEVPGPHSRKVTNMSKNRLKMIVYRLFWGQKSPRHRISIHDITKHFFPDQNEMQN

RKRLKLCADFKRTG-MD-SNWWVLKSDFRLPTE-EEIRAMVSPEQCCAYYSMIAAEQRLKDAGYGEKSFFAP-----EEENEEDF---QMKIDDEVRTAP
|.||| .....|.| || ..||.||....||.| ||||.|..||.||.|.||....|.|.||||.....|..      |...|..   |||||.|...||
RQRLKEFMKYQRDGGMDNQGWWKLKEGETLPDEFEEIRKMITPEDCCLYESMQVGQQHLEDAGYNNTDEFKRDYQQIQEDDDEETKKVQMKIDLEQMMAP

WNTTRAFIAAMKGKCLLEVTGVADPTGCGEGFSYVKI-PNKPT--QQKDDKEPQPVKKTVTGTDADLRRLSLKNAKQLLRKFGVPEEEIKKLSRWEVIDV
|||||.|| |..||..|.. |..||||||||||.... ..|..  .|.......| ||.|.||.|..|.....|..|..|..|||||||.....|.....
WNTTRNFINATQGKAMLQLHGEGDPTGCGEGFSFIRTKSMKGGFLKQGEGPQDKP-KKAVAGTRAKERGGHSYNVAQQQRLYGVPEEEIRRIWYWQKRSL
DUF3591 TAF1.AA DUF3591 1076-1098 38 6.463577 0.29 Pfam 469-494 (494) Show / Hide 
Range on Protein: 1076-1098
Range on HMM: 469-494/494
Sequence Identity: 38% (10 aa)

VAEHQERY---KEECQRIFDLQNKVL
||. |. |    ||  || . | . |
VAQQQRLYGVPEEEIRRIWYWQKRSL
BROMO TAF1.AA BROMO 1399-1507 26 2.4e-34 121.35 SMART 1-118 (118) Show / Hide 
Range on Protein: 1399-1507
Range on HMM: 1-118/118
Sequence Identity: 26% (32 aa)

RTDPMVTLSSILESIINDMRDL--------PNTYPFHTPVNAKV--VKDYYKIITRPMDLQTLRENVRKRLYPSREEFREHLELIVKNSATYNGPKHSLT
. . .  ....|..... ..|         | ..||. ||..|   . |||.||..||||.| ....... | |.||| . ..|...|  |||.| ..  
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNEPDSEVY

QISQSMLDLCDEKLKEKED
. .. . ... ||..| ..
KMAKKLQKFFEEKWREFPP
Bromodomain TAF1.AA Bromodomain 1410-1493 30 1.1e-25 86.12 Pfam 1-89 (89) Show / Hide 
Range on Protein: 1410-1493
Range on HMM: 1-89/89
Sequence Identity: 30% (27 aa)

LESIIN--DMRDLPNTYPFHTPV--NAKVVKDYYKIITRPMDLQTLRENVRKRLYP-SREEFREHLELIVKNSATYNGPKHSLTQISQS
.. |..  .. . |.. ||. ||  . ... |||.||..||||.| ..... . |  . .||....||. .|. |||||.. . .... 
CDQIMDMKYIMEHPICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK
BROMO TAF1.AA BROMO 1521-1630 34 6.5e-43 149.8 SMART 1-118 (118) Show / Hide 
Range on Protein: 1521-1630
Range on HMM: 1-118/118
Sequence Identity: 34% (41 aa)

DDDDQVAFSFILDNIVTQKMMA-------VPDSWPFHHPVNKKF--VPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANSVKYNGPESQYT
| . |  ....|. .. .|.         .|..|||..||..|   .||||..| |||||.||.|.. .|.|||.|.|.||..|.. |  .||.|.|.. 
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNEPDSEVY

KTAQEIVNVCYQTLTEYDE
| |... ... ....|. .
KMAKKLQKFFEEKWREFPP
Bromodomain TAF1.AA Bromodomain 1532-1616 37 3.8e-30 100.71 Pfam 1-89 (89) Show / Hide 
Range on Protein: 1532-1616
Range on HMM: 1-89/89
Sequence Identity: 37% (33 aa)

LDNIVT-QKMMAVPDSWPFHHPV--NKKFVPDYYKVIVNPMDLETIRKNISKHKYQ-SRESFLDDVNLILANSVKYNGPESQYTKTAQE
.|.|.. ...|  |...||.|||  ... .||||..| .||||.||....  .||. . . |. |..|.. |...||||.|.. | |..
CDQIMDMKYIMEHPICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNGPDSPIYKDARK