Gene ak1 (Slime mold)

ak1

Species: Slime mold
Alias: DdisK255, ak1, DDB0220120
External Links: DictyBase Link ,
Annotation:

Classification

Group: Atypical
Family: Alpha
Subfamily: Alpha-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
ak1.AA Protein None 1352 None Fasta, JSON
ak1.kin_dom Protein Kinase Domain None 8 None Fasta, JSON

Protein domain

Protein domains of ak1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ArfGap ak1.AA ArfGap 10-123 27 8e-31 111.1 Pfam 1-110 (110) Show / Hide 
Range on Protein: 10-123
Range on HMM: 1-110/110
Sequence Identity: 27% (33 aa)

YGLLRSLFQDPNNQCCAECNSANV-PYVCIKLGVFICPTCAHFLSTLG---FKVRPIMGSS-FSEEDISRLQSI-GNLVSKQFWLARWTPMDIVMPPPED
  .|| | . |.|. ||.|...|   .... ||.|||  |. .   ||    ||| .   . ...| | ..... || . ...|.|.          . .
KRVLRELRKQPGNKVCADCGAPNPVTWASWNLGIFICINCSGVHRSLGVHISKVRSLTMDKNWTPEQIEMMKAWGGNDKANEYWEAN----------DDH

PNLESFLRLKYIEKRWTSSL
   |.. | ||.||.|....
EKYEQWIRAKYEEKKWAEPN
ArfGap ak1.AA ArfGap 10-127 21 2.9e-15 57.97 SMART 1-139 (139) Show / Hide 
Range on Protein: 10-127
Range on HMM: 1-139/139
Sequence Identity: 21% (30 aa)

YGLLRSLFQDP-NNQCCAECNS-ANVPYVCIKLGVFICPTCAHFLSTL-G---FKV--RPIMGSSFSEEDISRLQ--SIGNLVSKQFWLARWTPMDIVMP
  .|..|   . .|  |..|.. .|. .. ...|||||  |. ..  | |   ..|  | .   .. .|.. |.|   .|| . ..||..   ...  ..
QQHLQMLRSIKPGNNKCFDCGAQPNPTWCSVNFGVFICIECSGIHRNLFGVHISFVNVRSLTMDNWTPEELRRMQQCKHGNENCNRFWESHLCDFSKWPK

PPE----------DPNLESFLRLKYIEKRW-TSSLSTSD
..           ... |.| | ||.||..    .....
DSDRHNPQKCQDCQQKYENFIRKKYEEKKFYCHCEKCEW
OmpH ak1.AA OmpH 113-435 5 0.019576 10.38 Pfam 48-118 (165) Show / Hide 
Range on Protein: 113-435
Range on HMM: 48-118/165
Sequence Identity: 5% (19 aa)

KYIEKRWTSSLSTSDGFSSPNNNNTSNVNNINNNSNHNNNINNNNNNINNNNNNNINNNNNIINNFSNINNISNGMNNISLNNINNNNNNNNHYNGNDIG
.. ..                                                                                               
QWQAE-----------------------------------------------------------------------------------------------

IPIVHKTQSQPQPQPQPQPQPQSQGFSPFNSPRSSPKPGRHHLIDDLISFNPTPVNNSNNNNNNNNNNNNGNNGNPLKFSGGIPQNNNNNNNNNTTTTTT
                                                                                                    
----------------------------------------------------------------------------------------------------

TTNNNNKVPFDPFSPIKTFSESGEYQNTNGNQQLSGSGNSLIDILSHPTQSKSPSPSGTPHSLSPQHHSSDFKVHLIDIPTTQQQLQQQQLQLQQQ----
                                                                              . . |..||..| ..|.|    
------------------------------------------------------------------------------LQKMQKELQKEQQKYQKQIRAG

----------------LQQQLQQQQQQQQ-QQQQQQQSPISNPF
                .||..||.||| | |. ||.|  . .|.
TMSEEQRQKKQQEFQQKQQEFQQYQQQYQPQEMQQKQQELMQPI
OmpH ak1.AA OmpH 470-747 9 3.2e-05 20.17 Pfam 43-113 (165) Show / Hide 
Range on Protein: 470-747
Range on HMM: 43-113/165
Sequence Identity: 9% (27 aa)

QQQQQQQQQQNGNNSPLAQFNQIQQQQINNNNPFVEEKQPHQHPHHLQHHRHHSTSSINHGSNGDLASISLTLLTPSPSPSPSFNYSGGVSSAPNNSLNN
.....|.|..                                                                                          
EKEFKQWQAE------------------------------------------------------------------------------------------

SCNGNNNLNNGMLNFSNLNIGGSTSSACSTNSSSNITIANNINSSNNINIINNQNNQNNNNNNNTNNVMISPSPSPNPFLPTPTSTNQNNHIITPIPVNP
                                                                                                    
----------------------------------------------------------------------------------------------------

FTDNLQLNSNNIRQHPQQMYIQQQQQQQQQQQQQQQQQ-QQ-QQQQQQQQQLQMQQQQQQQMQQHYQQQQQ-QQQQQQQQQ
                    .|. |.. |..||. |.| ..  . ..| |..|.. ||.||  | |||| | |. ||.||.
--------------------LQKMQKELQKEQQKYQKQIRAGTMSEEQRQKKQQEFQQKQQEFQQYQQQYQPQEMQQKQQE
SprA-related ak1.AA SprA-related 544-747 16 0.000546 15.31 Pfam 1-171 (321) Show / Hide 
Range on Protein: 544-747
Range on HMM: 1-171/321
Sequence Identity: 16% (44 aa)

TPSPSPSPSFNYSGGV-SSAPNNSLNNSCNGNNNLNNGMLNFSNLNIGGSTSSACSTNSSSNITIANNINSSNNINIINNQNNQNNNNNNNTNNVMISPS
  . ...||..|..|. .. .  . ||.                                                                        
MIITNSYPSISYYSGSPQGTEAARRNNT------------------------------------------------------------------------

PSPNPFLPTPTSTNQNNHIITPIPVNPFTDNLQLNSNNIRQHPQQMY-----------------------------------------------IQQQQQ
                         .... .   .| |. ..| . .                                                .| .|
-------------------------PRENIPQPSSSENSNNFPNSSSDATATSQTSTAVANDQSKQSEDGSTQPQFAKIFGQAQTQNGQASQEQQPQASQ

QQQQ----------QQQQQQQQQQQQQ--------QQQQQQLQMQQQQQQQMQQHYQQQQQQQQQQQQQQ
|...          .|.|..|||.|..        ||.||| | |..|||  ||. ||||||||||||||
QNDEDKQEQERDEVGQEQPEQQQAQAGFENATQQSQQRQQQDQ-QTRQQQ-AQQQEQQQQQQQQQQQQQQ
Alpha_kinase ak1.AA Alpha_kinase 995-1186 38 5.8e-111 375.85 SMART 1-255 (255) Show / Hide 
Range on Protein: 995-1186
Range on HMM: 1-255/255
Sequence Identity: 38% (99 aa)

LGKWVQTATIVIT-EPTPFAEGAMRKAFRMKDLSAE----GPSSQMVAKLFKDSNEDRM---VYFK--------DVEMQTYSKEIAERFNL---KSP-PK
 .||... |.|   ||.|||.||||......|.| .    .. ...|||.||.......   .||.        |||||. .|..|..||    . | ||
DNKWTCQETCVKIKEPKPFAKGAMRWCYWGCDWSEHMHCFCHGWECVAKYFKKEYKRTWDEERYFHETLHLCLRDVEMQMMCKHWANEFNQEAQHNPCPK

KIDFVPAFVMELV-------ERQGKPF----------------CAVEYFIEGKYEKHNNNFGYKNDYDRNT------------PQAFSHFSYEDSGCQLI
||||.|..|...        .|.....                ...| |.||...|.|||.|..|| .|.|            .|||||..||.|..|..
KIDFIPCYVFHFPRRIPAEYDRNIPYWFSYRTTDQMMVMCCCIFHMEPFMEGEFVKYNNNNGWVNDCMRWTTTSQRRTEMFEYCQAFSHWTYEWSNHQML

VVDIQGV----GD--VYTDPQIHSAD--GQGFGKGNLGIEGIKRFFSTHQCNPIC
|.|||||    ||  .|||||||..|  |.|||.|||| |||..||.|||||.||
VCDIQGVIHKNGDLYYYTDPQIHTEDQNGYGFGMGNLGQEGIEKFFQTHQCNQIC
Kinase ak1.AA Alpha_kinase 1012-1186 36 2e-86 298.25 Pfam 1-225 (225) Show / Hide 
Range on Protein: 1012-1186
Range on HMM: 1-225/225
Sequence Identity: 36% (83 aa)

FAEGAMRKAFRMKDL--SAEGPSSQMVAKLFKD----SNE-----DRMVYFKDVEMQTYSKEIAERFNLK-----SPPKKIDFVPAF-VMELVERQG---
||.||||..|||.|.  . ... . .|||..|     ..      ..  ||.|..||.......|.|| |     .||..|.|.... |.||  ...   
FAQGAMRWCFRMFDTWDPNWRNNQNCVAKWYKKIKNYNQKQSIYVEEDYYFQDCKMQMICQQWMEKFNQKLQEHNNPPPPIEFYDCCIVYELEDHNKPDC

------------KPFCAVEYFIEG-KYEKHNNNFGYK-NDYDRNTP-----QAFSHFSYEDSGCQLIVVDIQGVG--D---VYTDPQIHSADGQG---F-
            .... .| .||| ...|.|||.|.  .  |||.|     ||||||.|. |..|..|.||||||  .   ..||||||..||..   | 
YQGFFSYRTDWGGKYWYMEPYIEGCEFVKYNNNYGWVYDNMDRNDPWNQYMQAFSHFTYHRSNGQMMVCDIQGVGYNNKCYYLTDPQIHTKDGNYEMDFD

-GKGNLGIEGIKRFFS-THQCNPIC
 |.|||| |||..||. .|.||.||
EGMGNLGQEGIEKFFQNQHKCNHIC
Kinase ak1.AA Alpha 1001-1186 33 1.3e-64 182.67 In-house 1-215 (215) Show / Hide 
Range on Protein: 1001-1186
Range on HMM: 1-215/215
Sequence Identity: 33% (72 aa)

TATIVITEPTPFAEGAMRKAFRMKD--LSAEGPSSQMVAKLFKDSNEDRMVYFKDVEMQTYSKEIAERFNLKSPPKKI-------------DFVPAFVME
 .|..    .||.|||||.|.. .|  |  .   .| . .  .. ...   . |||| |.. . .   || .    ..              ||  .  |
QCTKIQMSSYPFMEGAMRYAMHAWDCWLHQKMVKKQHKKQWKSF-KYVWHHWIKDVERQMVCHHCVREFNQRLWEQEYTTHFNQMKPQPIKQFVHCYIYE

LVER--QGKPFCAVEYFIEGKYEKHNNNFGYKN----D-YDRNTPQAFSHFSYEDSGCQLIVVDIQ-GVG-DVYTDPQIHS----ADGQGFGKGNLGIEG
| ..   .... .|| ..||.|.| ||| |. .    |   . ..|||||.... |. ||.|||.| ||| . .||||||.    . |. ||.||.| ||
LIHCHNHNIKYYSVENYMEGEYQKYNNNAGWVDFLTDDNEFNQLMQAFSHWTWQYSNGQLMVVDLQWGVGEWKLTDPQIHCPAKLDQGMKFGDGNCGYEG

IKRFFSTH--QCNPIC
..|||.||  ||| .|
MFRFFYTHHVQCNHYC
Kinase ak1.AA VWL 1002-1191 37 1.8e-52 154.73 In-house 2-206 (206) Show / Hide 
Range on Protein: 1002-1191
Range on HMM: 2-206/206
Sequence Identity: 37% (78 aa)

ATIVITEPTPFAEGAMRKAFRMKDLSAEGPSSQMVAKLFKDSNEDR-----MVYFKDVEMQTYSKEIAERFN------LKSPPKKIDFVPAFVMELVERQ
 | |    .|||||||| |.  ||.       .||||..|  . .          ||.| |   . |   ||       ..... . ||  .. |. .  
KTKVRISNIPFAEGAMRYAYHAKDTYLN---QKMVAKQYKKQHKQNPKINKEDMIKDIESQFVCQHIVNCFNDRVSEHVQTTANILNFVHCYIYEVTHHY

GKP--FCAVEYFIEGKYEKHNNNFGYKNDYDRNTP----QAFSHFSYEDSGCQLIVVDIQGVG-DVYTDPQIHSADG-QGFGKGNLGIEGIKRFFSTHQC
...  .  || .||| |.| ||| |. |. |   .    ||||||..  |  .. .||.||..  . ||||||  |  . || |||| ||. |||.||||
NHNIKYYFVENYIEGDYQKYNNNAGWCNQTDM-EYNQLSQAFSHFTWQYSQGYCMIVDLQGNEDGMLTDPQIHCLDQSHKFGQGNLGYEGMLRFFMTHQC

NPICHYLGL
| .|  | |
NKYCQKLQL
Kinase ak1.AA Alpha-Unclassified 1079-1186 28 1.2e-27 87.11 In-house 92-215 (215) Show / Hide 
Range on Protein: 1079-1186
Range on HMM: 92-215/215
Sequence Identity: 28% (35 aa)

VPAFVMELVERQGKPFCAVEYFIEGKYEKHNNNFG------YKNDYDRNTPQAFSHFSYEDSGCQLIVVDIQG-VG------DVYTDPQIHSADGQGFG-
.| | . . ..  | .  ||  ..| . | .|| |       . .      ....|..|. .. ..||.| || |.         ||||||. . |... 
PPIFLIHREDKNIKGCISVEPYLIGEFVKYSNNTGKEINFVKWEYEAYQYCCTYQHWTYQWTNHCDIVCDLQGWVDENDKKTWKMTDPQIHTIR-QRYQG

-KGNLGIEGIKRFFSTH--QCNPIC
 |.| |  .| ..|. |  ||| .|
FKTNCGMRFIDYWFNNHHVQCNHYC
Kinase ak1.AA ChaK 1096-1186 36 2.3e-12 45.16 In-house 121-219 (219) Show / Hide 
Range on Protein: 1096-1186
Range on HMM: 121-219/219
Sequence Identity: 36% (36 aa)

AVEYFIEGKYEKHNNNFGYKNDYDRNTPQ----AFSHFSYEDSGCQLIVVDIQGVGDVYTDPQIHSAD-----GQGFGKGNLGIEGIKRFFSTHQCNPIC
..| .. | . | ||| |       ||      ||||. ||     |.|.|.||||.  ||| .  ..     .  ||  ||| . |. |   | ||  |
TIEKCMTGEFRKYNNNNG-DEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKPEEKQSCDMVFGPANLGEDAIRNFRAKHHCNSCC