Gene TRRAP (Slime mold)

TRRAP

Species: Slime mold
Alias: DDB0229338c, DdisK281, tra1, TRRAP
External Links: DictyBase Link ,
Annotation:

Classification

Group: Atypical
Family: PIKK
Subfamily: TRRAP

Sequence

Name Sequence Type Origin Length Description Download
TRRAP.AA Protein None 4583 None Fasta, JSON
TRRAP.kin_dom Protein Kinase Domain None 8 None Fasta, JSON

Protein domain

Protein domains of TRRAP.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
FAT TRRAP.AA FAT 3319-3708 17 7e-34 113.68 Pfam 1-408 (408) Show / Hide 
Range on Protein: 3319-3708
Range on HMM: 1-408/408
Sequence Identity: 17% (79 aa)

YDLTIESAWKIPQWNS-----VKENMK------------KMMSQGDTSIRKILQGYFLT--NEKRYH--EVDPAIVTSNQLILDKWVS-LPERSFRSHTN
 .|  |.||  .||..       ..||            . .....|  | . |.. .     ...   |.   |    || ...| . || .|  .| .
APLAAEAAWRLGQWDETYMDEYISVMKKLLGEDQLTFIDEDSPDEPTWDRSFFQAILCLYKHHNQFDTYEAHRYIDKARQLLDTEWTACLPGESYNRHYP

SLVEMQQVVELQESVHILKEISNITLSQQPADLSRSFLTSNYIKSIFNIWRERLPN-KDEDLLIWFELMAWRQQVFNIIGTPSMNGGIGANPVTPTNTTT
 .|  |. .||.|.  .    .. ..   . ....       .|.... |..|||. |  .. .|  ...||| || .|..  |                
VMVRVQMLAELEEIIQYKSQCNQNNAQNLDNSPEK-------QKHMRQTWWKRLPGCKQRNVEVWQRILTWRQHVFSKINQRYM----------------

TITNPDGTTTTTTTPLPPPQQPINQIEFASPRYM-VLEMAWTMNKYSHIVRKHNIIEVCLNSLSKMF-------------DLQIEL------------HD
                             | .|.   | .|. .|.... |||.  ..| ..|..               . |..             ..
----------------------------NSFCYRGPHEDMWMWIKFANLCRKHGRMQLCEKTLKMLYTYDPSEEDWHPRAPPQWTYAYLKYMWATGQQQE

IFLNLKEQIKCYLQLP------THYDTGI----SIINSTNLDFFTPMQKG-EFLQLKGEFLNRL----------GRYDEANQSFASSVSQYENSAK-NWI
 |. |.|...|..| .        .  |     . ||.|||  |   ... ..  ..|.... |          .. ||..|...  .    ...|  | 
AFQHLREFTSCHMQHDLGVHNNNEIN-GLTYNLEVINNTNLEYFYTKLLAMRCYHKQGMWQWKLYEEQYMNWNQEQKDEILQCYMTATHFDPQWYKKAWH

SWAHFCDNQFTNHSSSSITPSSTPTTY-DIKTQWAESAISCYIQGIKCDPK-YGSRYVPRIFW
.||.. .. |.   . . . ...   | ..  | .  |..|... |.   .     . .|. |
NWALYNFEVFQHYQCQPQREEQN---YTHMIIQHVVPAVKCFFHSIALSQGSNSRQDTLRLLW
Kinase TRRAP.AA ATR 4450-4493 22 7e-06 15.47 In-house 224-267 (267) Show / Hide 
Range on Protein: 4450-4493
Range on HMM: 224-267/267
Sequence Identity: 22% (10 aa)

RLSPNIRNYLGPLYLEGSYLSSMISTCICLSDLKDQLVNSINLF
||  |. . .||.  .| .   .. .. |..| .|...  .. |
RLTHNMVFGMGPMKTYGLFRRACEVIMMCMRDHRDDIMSVWDCF
Kinase TRRAP.AA PIKK 4450-4493 25 0.000107 13.45 In-house 247-290 (290) Show / Hide 
Range on Protein: 4450-4493
Range on HMM: 247-290/290
Sequence Identity: 25% (11 aa)

RLSPNIRNYLGPLYLEGSYLSSMISTCICLSDLKDQLVNSINLF
|| .|. | .||  .|| . ....... |... .. | .    |
RLTRNMVNAMGPMGVEGVFRRCCEHVMMCMRQHRETLMTVCEVF
Kinase TRRAP.AA PIKK 4175-4247 27 0.000228 12.24 In-house 20-78 (290) Show / Hide 
Range on Protein: 4175-4247
Range on HMM: 20-78/290
Sequence Identity: 27% (20 aa)

RITLYGGNGKAYQFLIESSPSLINGITNSNNNNVARVYERKNQLLGSINSMLIKNRETRRRGLTLNSYPTVVP
.|.. | .|| | .|         |.. .      |  .|  ||.. .| .| |. |...| |.. .| .|.|
KIYIRGHDGKEYPYLCK-------GHEDL------RQDQRVMQLFQLMNTCLQKDPECQKRHLHIRTY-SVIP
Kinase TRRAP.AA PI3Kc 4215-4560 11 0.000601 -104.13 SMART 5-336 (336) Show / Hide 
Range on Protein: 4215-4560
Range on HMM: 5-336/336
Sequence Identity: 11% (48 aa)

KN-----------QLLGSINSMLIKNRETRRRGLTLNSYPTVVPIKNSLTMIQNI-GNDSIKQLA-----------------------------------
|.           |... .| .. |..|.||| |... |  ..|.     ||. .   ... |.                                    
KCGDDLRQDMRMMQMFRLMNKIWQKDKECRRRDLHMRPYK-CIPTGPKCGMIEWVPNCETLHQIQKKYHKWKKMPMDYHQWFMFDMLVPEIQKNMYMMIW

----EVWYTHSNQSNLFKPMLKYKEMLLNSN----LHTELLSKKDQDGDLEFTNITEDNNISSSSSSSSSSGSNSGENSPIIDSSKLVVFREMSKEIGDE
    ..| ... ...... .||| |. ....    |.  ....  ...                                                    
HQQACHWMMMYQHMTHME-WLKYFEGATCPFKPPVLYDWFWEHFPDPN----------------------------------------------------

LMINYIQSTLLPTNYQDQYEFKLNFSNQFGLHSLLQYILFSDIGDIDPSKIYLTKSTGSVYYNDWSLKLTNRKLGFDL---LQDNPYNQQQLLRLSPNIR
                | .|.. ||  .    .   |||   |||  ...| |.. || .   |    ... .. .     .     .     || ... 
---------------EDWWEARDNFTRSCAGYCMVTYIL--GIGDRHNDNIMLDMKTGHCFHIDFGHIFGHGPKKPGFKHHH-----RERVPFRLTHDMV

NYLG----PLYLEGSYLSSMISTCICLSDLKDQLVNSINLFIFDEY-MCMNNVEPLQQSEQNKDRNIHYEFIDKTTATVHQMLEN----RIDSLTPSSQP
.  |    |  ..| . . . ..   .   .....| ..... |.   | .  |   . .... | .|     ..   . |. ..     ... . .|..
YVMGGGGKPSGYFGYFRTCCCRAYRAMRKHSNLIMNLFEMMVYDPIMPCWRMMEKDIKYLRQRFRLDH-----LSDEEAAQYFMQTMCTKLIEHSNESWT

DKTCFISPIVKKV
 .. ..   ... 
TRMYWMFHNWAQY