Gene DDB0220004 (Slime mold)

DDB0220004

Species: Slime mold
Alias: DdisK138, DDB0220004
External Links: DictyBase Link ,
Annotation:

Classification

Group: Other
Family: WEE
Subfamily: WEE1

Sequence

Name Sequence Type Origin Length Description Download
DDB0220004.AA Protein None 998 None Fasta, JSON
DDB0220004.kin_dom Protein Kinase Domain None 342 None Fasta, JSON

Protein domain

Protein domains of DDB0220004.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase DDB0220004.AA WEE 508-849 39 1.7e-164 552.81 In-house 1-297 (297) Show / Hide 
Range on Protein: 508-849
Range on HMM: 1-297/297
Sequence Identity: 39% (142 aa)

FQELDLIGEGSFGHVYKVRHRIDGCLYAIKKTKKPLKGQKDRDIVLREVYGLSAIK------DHTNIVRYFNAWEEDSHIFIQMEHCNGGN--IYKWVTE
|||.. |||||||.|||.|.|||||.|||||.|.|..|...|.  |||||... ..      .|..||||..|||||.|..||||.||||.  ...|...
FQEVQKIGEGSFGEVYKCRCRIDGCIYAIKKSKQPFRGYSERKRALREVYAHMVLGQIMDCDHHPHIVRYYSAWEEDDHMYIQMEYCNGGSNLLQFWIQQ

HIK----QSESNLLLLAKQILTGIVYIHSL-GLVHLDIKPENIYIIYKCNQNQIITNNNNTCSINNSSNGSDSYFKSKIKTTENDLDNFITTTNSVNNNN
...    ..|...  .  .|..|. .|||  |.||.|||||||.|..|.|.|||. ||                                          
CHNWNHWLPEWMIWQILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIV-NN------------------------------------------

CNNNNNNNVDNQNNNNQNNYLIIDGNKINFNSITFKIGDLGLLNEAT----NTKIYSEGDSRYLSRELLHD--DMSALKKSDIFSLGCTLYELARCKPLP
         |.||||..          . || ...||||.|......    |.. ..||||||...|.|..  ... |.|.||||||.|.||||....||
---------DQQNNNDW----------W-FN-MMCKIGDFGHVTDMNSNNNNPHQEQEGDSRYMAPEILQGYYHYTHLYKADIFSLGITIYELACNMDLP

KSGMEWDSIRNGILSFEKEDSIYDDNKNDFSTEFWQLIKSMIHPDPSVRPSAEQLLEHPLI
|.|..|..||.|.|||.|.. ......|..|.|..||||.|.||||. ||...|||.||..
KNGDWWHQIRQGDLSFDKNQIPFPEFDNIISQELKQLIKWMMHPDPEQRPTCQQLLQHPVL
Kinase DDB0220004.AA Pkinase 508-849 21 1.1e-52 186.17 Pfam 1-293 (293) Show / Hide 
Range on Protein: 508-849
Range on HMM: 1-293/293
Sequence Identity: 21% (81 aa)

FQELDLIGEGSFGHVYKVRHRIDGCLYAIKKTKKPLKGQKDRDIVLR--EVYGLSAIKDHTNIVRYFNAWEEDSHIFIQMEHCNGG----NIYKWVT--E
.. .  ||.|||| ||| .|. .|...|.|. ||. .  . . . .|  |.. .  . .| ||||.. ..|...|| . ||.|.||      . ...  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

HIKQ--SESNLLLLAKQILTGIVYIHSLGLVHLDIKPENIYIIYKCNQNQIITNNNNTCSINNSSNGSDSYFKSKIKTTENDLDNFITTTNSVNNNNCNN
| .   ||  .   ..||| |. |.|| | .| |.||||| |  ... .                                                   
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA--------------------------------------------------

NNNNNVDNQNNNNQNNYLIIDGNKINFNSITFKIGDLGL-----LNEATNTKIYSEGDSRYLSRELLHDDMSALKKSDIFSLGCTLYELARCKPLPKSG-
                              ..||.| ||     .   . .. .  | ..|.. |.. ..    .|.|..|.||.|||..  .|. ..  
------------------------------CVKICDFGLAKQFDY-NNS-MTTF-CGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHC

----MEWDSIRNGILSFEKEDSIYDDNKND---------------FSTEFWQLIKSMIHPDPSVRPSAEQLLEHPLI
    .. . . . |.. . . ... .. .                 | |. ..||.....||. ||.|||.|.|| .
WHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase DDB0220004.AA S_TKc 508-849 18 6e-44 153.25 SMART 1-231 (231) Show / Hide 
Range on Protein: 508-849
Range on HMM: 1-231/231
Sequence Identity: 18% (69 aa)

FQELDLIGEGSFGHVYKVRHRIDGCLYAIKKTKKPLKGQKDRDIVLREVYGLSAIKDHTNIVRYFNAWEEDSHIFIQMEHCNG--GNIYKWVTEHIK---
.. |..||.|.|| |||.||. .| ..|||. |         . ..||.  |.   .| |||... .... .|... ||.|.|  |. ..   .. .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---QSESNLLLLAKQILTGIVYIHSLGLVHLDIKPENIYI----------IYKCNQNQIITNNNNTCSINNSSNGSDSYFKSKIKTTENDLDNFITTTNS
    .|     ...||. .. |.||.| .| |.||||| .          . .                                               
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL---------------------------------------------

VNNNNCNNNNNNNVDNQNNNNQNNYLIIDGNKINFNSITFKIGDLGLLNEATNTKIYSEGDSRYLSRELLHDDMSALK-KSDIFSLGCTLYELARCKPLP
                                                    .| . .     |.. |.|    .  | |.|. |.||.|||..  .|. 
----------------------------------------------------TTFCGTPW---YMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPF

KSGMEWDSIRNGILSFEKEDSIYDDNKNDFSTEFWQLIKSMIHPDPSVRPSAEQLLE-------HPLI
    . . . . |.                | |....|. . . ||. ||.| ..|.       || .
P---QMQMMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase DDB0220004.AA Ciliate-E2 508-849 17 1.3e-39 133.59 In-house 1-365 (365) Show / Hide 
Range on Protein: 508-849
Range on HMM: 1-365/365
Sequence Identity: 17% (79 aa)

FQELDLIGEGSFGHVYKVRHRIDGCLYAIK-------------KTK---KPLKGQ--KDRDIVLREVYGLSAIK---------------DHTNIVRYFNA
.  . .||.|.|| |||.... .....|||             |.|   . .| .  ..  ....| . .  |.               .| ||.... .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

WE--EDSHIFIQMEHCNGGNIYKWVTEHIKQS-----------ESNLLLLAKQILT---------------GIVYIHSLG-LVHLDIKPENIYIIYKCNQ
..   |..|.. || |.||. ...  .. |..           |   . . ||||                .. |.|| .  .| ||||||| .      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

NQIITNNNNTCSINNSSNGSDSYFKSKIKTTENDLDNFITTTNSVNNNNCNNNNNNNVDNQNNNNQNNYLIIDGNKINFNSITFKIGDLGL---------
                                                                                    || |.||         
-----------------------------------------------------------------------------------IKIIDFGLSKKYDDDNQ

-------LNEATNTKIYSEGDSR-------------------YLSRELLHDDMS--------ALKKSDIFSLGCTLYELARCKPLPKSGMEWDSIRNGIL
        .. .. | . .. ..                   |...| |               .|.||.|||..|||.  .. .|      . | .. .
NRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEML-FGKPPF----QQQIKQCKI

SFEKEDSIYDDNK---------NDFSTEFWQLIKS----MIHPDPSVRPS-AEQLLEHPLI
.| ..... |  .         .. | |  .|||     |.  ||. |.. .||.|.|| .
DFPCPEWQKD-TQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase DDB0220004.AA CAMK 513-637 22 3e-34 107.23 In-house 259-468 (425) Show / Hide 
Range on Protein: 513-637
Range on HMM: 259-468/425
Sequence Identity: 22% (47 aa)

LIGEGSFGHVYKVRHRIDG------------CLYAIKKTKKP-LKG-------------------------QKDRDIVLREVYGLSAIK------DHTNI
 .|.|||| |....|. ..              .|||  .|  ||.                         .|||. |.||.  .. ..      || ||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRYFNAWEE-------------------DSHIFIQM---EHCNGG----NIYKWVTEH---------------IKQSESNLLLLAKQILTGIVYIHSLGL
.. . ..|                    |.|... |   |.| ||     .. ...||                . .|.    . .||. .. |.||.. 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

VHLDIKPENI
||.|.|||||
VHRDLKPENI
Kinase DDB0220004.AA Ciliate-E2a 508-637 28 7e-33 94.13 In-house 1-133 (275) Show / Hide 
Range on Protein: 508-637
Range on HMM: 1-133/275
Sequence Identity: 28% (39 aa)

FQELDLIGEGSFGHVYKVRHRIDGCLYAIKKTKKPLKGQKD--RDIVLREVYGLSAIKDHTNIVRYFNAWEEDSHIFIQMEHCNGGNIYKWVTEHIKQSE
.  ...||.|.||.||...|...|  .|.|| .|    |..  .  . .|.  .. . || || . .  .| ...... || |.||  |.   .. .. |
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQL-DHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFE

S--NLLLLAKQIL-TGIVYIHSLGLVHLDIKPENI
   .   . .|.|  |. |.|... .| |.|||||
EIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENI
Kinase DDB0220004.AA CAMKL 508-637 27 1.4e-28 88.23 In-house 175-332 (297) Show / Hide 
Range on Protein: 508-637
Range on HMM: 175-332/297
Sequence Identity: 27% (44 aa)

FQELDLIGEGSFGHVYKVRH-RIDGCLYAIKKTKKPLKG--------------QKDRDIVLREVYGLSAIK--DHTNIVRYFNAWEEDSH------IFIQ
.. .. .|.|||| |   .| |. |. .|||  .|  .               ..|   . ||.  .. ..   | ||.. .  .| ..|      |.. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDM-RIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLV

MEHCNGGN--IYKWVTEH----IKQSESNLLLLAKQILTGIVYIHSLGLVHLDIKPENI
||.| ||.   . .. .|     . .|.    . .||. .. |.||.| || |||||||
MEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENI
Kinase DDB0220004.AA STE 508-637 21 1.4e-25 87.39 In-house 33-215 (359) Show / Hide 
Range on Protein: 508-637
Range on HMM: 33-215/359
Sequence Identity: 21% (40 aa)

FQELDLIGEGSFGHVYKVRHRI---------------DGCLYAIKKTK----KPLKGQ------------KDRDIVLREVYGLSAIKD-HTNIVRYFNAW
.. .. ||.|.|| ||| ...                 |...|||. .    .. . .            .... .|.|.  ..  .. | |||.|. . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

EED-------SHIFIQMEHCNGGNIYKWVTE--HIKQS------------ESNLLLLAKQILTG-IVYIHSLGLVHLDIKPENI
. .       ....| ||...|| . . . .   ....            || .   ..||| |   |.||.. .| |||| ||
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANI
Kinase DDB0220004.AA PEK 508-578 41 7.5e-24 79.35 In-house 222-307 (655) Show / Hide 
Range on Protein: 508-578
Range on HMM: 222-307/655
Sequence Identity: 41% (36 aa)

FQELDLIGEGSF-GHVYKVRHRIDGCLYAIKKTKKPLKG---------------QKDRDIVLREVYGLSAIKDHTNIVRYFNAWEED
|.|....| | | | ||||....|||.||||. | . |.               .| .. |||||  |.   .| |||||.||| |.
FEEIQCLGKGGFGGQVYKVQNKLDGCYYAIKRIKLNWKQRKQPCITQECMIHKCKKHCEKVLREVKTLARL-NHPNIVRYHNAWIEK
Kinase DDB0220004.AA NEK 508-637 29 2.9e-22 75.49 In-house 1-150 (286) Show / Hide 
Range on Protein: 508-637
Range on HMM: 1-150/286
Sequence Identity: 29% (45 aa)

FQELDLIGEGSFGHVYKVRHRIDGCL-----YAIKKTKKPLKG--QKDRDIVL-REVYGLSAIKDHTNIVRYFNAWEEDS--HIFIQMEHCN-GGNIYKW
....  ||.|||| |||||...||       |..|| .  ...  .|...  .  ||  |. .| | |||.|.....|.   ...| ||.|. ||. |. 
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKIN--MGNMSEKEKQNAQNNEVRILKQLK-HPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQK

---VTEHI----KQSESNLLLLAKQILTGIVYIHSL-----GLVHLDIKPENI
     ..       .|.  .    |.. .. |.|.        .| |||| ||
IKSIKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNI
Kinase DDB0220004.AA PEK 508-577 40 2.1e-21 67.18 In-house 352-427 (758) Show / Hide 
Range on Protein: 508-577
Range on HMM: 352-427/758
Sequence Identity: 40% (31 aa)

FQELDLIGEGSFGHVYKVRHRIDGCLYAIKKTKKPL-------KGQKDRDIVLREVYGLSAIKDHTNIVRYFNAWEE
| . . .| |.|| |...    |...||||.   |           . |. |.|||  | |. || |||||||||.|
FEHIQCLGHGGFGVVFRAKNKVDMNNYAIKRITFPNSNNQSPTNRESAREKVMREVRTL-AMLDHHNIVRYFNAWLE
Kinase DDB0220004.AA GCN2 508-575 40 4.4e-19 63.12 In-house 1-70 (511) Show / Hide 
Range on Protein: 508-575
Range on HMM: 1-70/511
Sequence Identity: 40% (29 aa)

FQELDLIGEGSFGHVYK-VRHRIDGCLYAIKKTKKPLKGQKDRDI--VLREVYGLSAIKDHTNIVRYFNAW
|.|....| | || |.| || . ||..||||| . . |..|.. .   .|||  |. .. | ..|||..||
FEEICCLGKGGFGQVVKNVRNMHDGRYYAIKKWPINWKQRKLPCKHKIMREVKLLC-RLHHQHVVRYYQAW
Kinase DDB0220004.AA PEK 580-736 13 3e-14 45.33 In-house 357-478 (655) Show / Hide 
Range on Protein: 580-736
Range on HMM: 357-478/655
Sequence Identity: 13% (28 aa)

HIFIQMEHCNGGNIYKWVTEH--------------------------------------------IKQSESNLLLLAKQILTGIVYIHSLGLVHLDIKPE
. .||||.|....   |  ..                                             ....  .. ...|||.|  |||| |..| |.|| 
YLYIQMEYCEKKTLRDWIDNNGCPVQFNYWRRNSCKNHYNNYIMNQCCFQSTWSMNMRQWDENNCMFWDKDQCWRIFRQILEGLNYIHSQGMIHRDLKPS

NIYIIYKCNQNQIITNNNNTCSINNSSNGSDSYFKSKIKTTENDLDNFITTTNSVNNNNCNNNNNNNVDNQNNNNQNNYLIIDGNKINFNSITFKIGDLG
||.. .. .. |                                                                                  |||| |
NIFLDCDGQHHQ-------------------------------------------------------------------------------MQVKIGDFG

L
|
L
Kinase DDB0220004.AA STE 768-849 25 3.3e-13 43.12 In-house 248-359 (359) Show / Hide 
Range on Protein: 768-849
Range on HMM: 248-359/359
Sequence Identity: 25% (29 aa)

KSDIFSLGCTLYELARCKPL----PKSGMEWDSIRN---------------GILSFEKEDSIYDDNKN----------DFSTEFWQLIKSMIHPDPSVRP
|.|| |||||. |.|  ||     .   . .  ..|               .. ... . |  .  ..           .| || . |.     ||. ||
KCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEM-ISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRP

SAEQLLE--HPLI
.|.|||.  || |
TASQLLKSEHPFI
Kinase DDB0220004.AA TyrKc 508-849 16 1.5e-11 -36.08 SMART 1-280 (280) Show / Hide 
Range on Protein: 508-849
Range on HMM: 1-280/280
Sequence Identity: 16% (64 aa)

FQELDLIGEGSFGHVYKVRHRIDGCLYAIKKTKKPLKGQKDRDIVLREVYGLSAI-KDHTNIVRYFNAWEED-------SHIFIQMEHCNGGNIYKWVTE
 . .. .||| || ||| . .      |.|. |.       |   .||   .. . ..| |||| . .  ..         ..| ||.. .|.  .   .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

HIK-QSESNLLLLAKQILTGIVYIHSLGLVHLDIKPENIYIIYKCNQNQIITNNNNTCSINNSSNGSDSYFKSKIKTTENDLDNFITTTNSVNNNNCNNN
| .  . . ||  . ||  |  |.|| ...| |.   |. .  .                                                        
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-------------------------------------------------------

NNNNVDNQNNNNQNNYLIIDGNKINFNSITFKIGDLGLLNEATNT-------KIYSE-----GDS----RYLSRELLHDDMSALKKSDIFSLGCTLYELA
                             | ||.| ||  . ..        . |.      |..    | .. | . ..     |||..| | ...|. 
-----------------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSDVWSFGVCMWEIF

RCKPLPKSG-----MEWDSIRNGILSF---EKEDSIYDDNKND-----FSTEFWQLIKSMIHPDPSVRPSAEQLLEHPLI
     | .|     |... ... . .    .. ...|            ..|  |..|.  | ||. ||. ...  | ..
TYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-----PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase DDB0220004.AA GCN2 581-639 38 4.3e-10 31.12 In-house 282-341 (511) Show / Hide 
Range on Protein: 581-639
Range on HMM: 282-341/511
Sequence Identity: 38% (23 aa)

IFIQMEHCNGGNIYKWVTEHIKQSESN-LLLLAKQILTGIVYIHSLGLVHLDIKPENIYI
..||||.| |.. .   ..|  ....  |  .. ||| | .|||| | .| |.|| ||..
LYIQMEYCEGKTLRQYIDNHGWCMDHDELWRYFRQILEGLNYIHSQGMIHRDLKPSNIFL
Kinase DDB0220004.AA CAMK 767-849 22 4.7e-10 27.84 In-house 313-425 (425) Show / Hide 
Range on Protein: 767-849
Range on HMM: 313-425/425
Sequence Identity: 22% (26 aa)

KKSDIFSLGCTLYELARCKPLPKSGM-----------------EWDSIRNGILSFEKE-------------DSIYDDN--KNDFSTEFWQLIKSMIHPDP
.|.|. |.|. || .  |  .|  |                   .  |..|  .|. .             ..   |.  .  .|.|  .||..|  .||
PKCDMWSCGVILYIML-CGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQECKDLIRKMLQVDP

SVRPSAEQLLEHPLI
. |...|| |.|| .
EKRMTIEQCLNHPWM
Kinase DDB0220004.AA GCN2 817-849 32 6.8e-10 30.4 In-house 472-511 (511) Show / Hide 
Range on Protein: 817-849
Range on HMM: 472-511/511
Sequence Identity: 32% (13 aa)

DFS-------TEFWQLIKSMIHPDPSVRPSAEQLLEHPLI
||        ... ..|.... .||. ||||.|||.|...
DFDKKVDNHHKDQQDMIRWCLNHDPQKRPSAQQLLQHEFL
Kinase DDB0220004.AA PEK 824-849 42 1.4e-09 28.78 In-house 630-655 (655) Show / Hide 
Range on Protein: 824-849
Range on HMM: 630-655/655
Sequence Identity: 42% (11 aa)

QLIKSMIHPDPSVRPSAEQLLEHPLI
..|. |...||. ||||.|.|.|...
DFIQWMLSHDPQQRPSAQQILQHEFF
Kinase DDB0220004.AA NEK 824-849 50 1.4e-08 26.72 In-house 261-286 (286) Show / Hide 
Range on Protein: 824-849
Range on HMM: 261-286/286
Sequence Identity: 50% (13 aa)

QLIKSMIHPDPSVRPSAEQLLEHPLI
.|| .|...||. |||..|.||.|.|
NLISQMLQKDPEQRPSCNQILEMPFI
Kinase DDB0220004.AA PEK 825-849 32 6.8e-08 21.15 In-house 734-758 (758) Show / Hide 
Range on Protein: 825-849
Range on HMM: 734-758/758
Sequence Identity: 32% (8 aa)

LIKSMIHPDPSVRPSAEQLLEHPLI
.|. |....|. ||.| |...|.. 
FIQQMMSMNPDERPTADQISMHDFF
Kinase DDB0220004.AA Ciliate-E2a 816-849 38 1.7e-07 18.13 In-house 242-275 (275) Show / Hide 
Range on Protein: 816-849
Range on HMM: 242-275/275
Sequence Identity: 38% (13 aa)

NDFSTEFWQLIKSMIHPDPSVRPSAEQLLEHPLI
...| |  .|.| |  .||. |..|.|.|.||  
EKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase DDB0220004.AA CAMKL 805-849 24 2e-07 19.59 In-house 255-297 (297) Show / Hide 
Range on Protein: 805-849
Range on HMM: 255-297/297
Sequence Identity: 24% (11 aa)

EKEDSIYDDNKNDFSTEFWQLIKSMIHPDPSVRPSAEQLLEHPLI
....  |..  .. | .  .||..|  ..|. ||...|...||  
IMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase DDB0220004.AA PEK 580-637 32 1e-06 16.95 In-house 413-473 (758) Show / Hide 
Range on Protein: 580-637
Range on HMM: 413-473/758
Sequence Identity: 32% (20 aa)

HIFIQMEHCNGGNIYKWVTE--HIKQSESNLLL-LAKQILTGIVYIHSLGLVHLDIKPENI
. .|||. | . .   |      ... . .. | . .||..|. |||| |. | | || ||
YMYIQMQLCRKETLKDWMRNRCTMESRPWMHMLHWFHQICEGVNYIHSKGMIHRDLKPSNI
Kinase DDB0220004.AA Pkinase_Tyr 508-629 24 1.7e-05 19.21 Pfam 1-134 (270) Show / Hide 
Range on Protein: 508-629
Range on HMM: 1-134/270
Sequence Identity: 24% (33 aa)

FQELDLIGEGSFGHVYKVRHR----IDGCLYAIKKTKKPLKGQKD--RDIVLREVYGLSAIKDHTNIVRYFNAWE-EDSH--IFIQMEHCNGGNIYKWVT
 . .  .|||.||.||| . .     ...  |.|.  |.   ...  |.  .||.  .. . .| ||||.  .   .. .  |.| ||.. .|. ..   
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

EH----IKQSESNLLLLAKQILTGIVYIHSLGLVH
.|     . . . ||  . ||  |  | .| ...|
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIH
Kinase DDB0220004.AA NEK 768-786 57 0.0003 11.32 In-house 204-224 (286) Show / Hide 
Range on Protein: 768-786
Range on HMM: 204-224/286
Sequence Identity: 57% (12 aa)

KSDIFSLGCTLYELARC--KP
|||| |||| |||.. .  |.
KSDIWSLGCVLYEMCTLKPKH
Kinase DDB0220004.AA Ciliate-E2a 767-779 38 0.029339 2.48 In-house 195-207 (275) Show / Hide 
Range on Protein: 767-779
Range on HMM: 195-207/275
Sequence Identity: 38% (5 aa)

KKSDIFSLGCTLY
.| |..|.|. .|
TKCDMWSCGVIFY