Gene DDB0231326 (Slime mold)
DDB0231326
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| DDB0231326.AA | Protein | None | 2454 | None | Fasta, JSON |
| DDB0231326.kin_dom | Protein Kinase Domain | None | 243 | None | Fasta, JSON |
Protein domains of DDB0231326.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| S_TKc | DDB0231326.AA | S_TKc | 1730-2028 | 18 | 9.2e-20 | 72.9 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 1730-2028 Range on HMM: 1-231/231 Sequence Identity: 18% (58 aa) FKDLKRVAKGAYGTVYKGTLGNDEGLEIAVKLMPVPKTIHDRCVLYDIFTEILIMDTFRSDSRGCHMFDYGVDGENYWIVMKSYKC---SLKEWRLKQTL .. |. . |||.|.|||.. . | . |.| .. .| || |. ....|. .| .....|| .|.. |. YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK-----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR P---FLELLPLLLNIFTNVLQSVQFLGDHKINHFDIKCDNFLVHPLKKGTIEEDFWNQPTNDPNFAVCLADWGEAKVYTQDVEGYTTRNRGTEFIKSPEM . | .. ... .... .|.| | |.| .| |. . ..| | |... | || . .||. HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--------------------HIKICDFGLARQL--------TTFCGTPWYMAPEV LTIAYASQKTRENFDRRKKVGSNT-ASDVWSLGCLFYELLTGDFLFYDDDWVKFFIRVTQPGQELITPERKSKVANIPAILDYLDYVFIRDPFYRPTLRD | | .. ..|.||.||..||.|.| .|. .. . | . . | .| .. . .|| ||| . L-------------------GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG------------------SPEAKDFIRKCLQKDPEKRPTA-E LLT--------KFI .|. .. ALQDEWDIKCHPWF |
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| Pkinase | DDB0231326.AA | Pkinase | 1730-2027 | 17 | 3e-18 | 65.62 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 1730-2027 Range on HMM: 1-293/293 Sequence Identity: 17% (58 aa) FKDLKRVAKGAYGTVYKGTLGNDEGLEIAVKLMPVPKTIHDRCV----LYDIFTEILIMDTFRSDSRGCHMFDYGVDGENYWIVMKSYKC-----SLKEW .. .... .|..|.|||.. ... . ||| ...... .. .. | .|| || .... . ..|. |. ....|| . .|. YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRL----SEIQIMKRLNHPN-IVRLYDWFEDKDHIYMVMEYCEGGLYVMDLF-D RLK--QTLPFLEL-LPLLLNIFTNVLQSVQFLGDHKINHFDIKCDNFLVHPLKKGTIEEDFWNQPTNDPNFAVCLADWGEAKVY-TQDVEGYTTRNRGTE ... . .|. . . .... .|. .... ...| | |.| .|.|.. ..|.|.. |...|.| ||.. . . .||. || YISTWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID--NNGHIDA------------CVKICDFGLAKQFDY-NNS-MTTF-CGTP FIKSPEMLTIAYASQKTRENFDRRKKVGSNTASDVWSLGCLFYELLTGDFLFYDD-----DWVKFFIRVTQPGQELITPERKSKVANI------------ . .|| . . . ...|.||.||..||.|.| ..|... . .. |. . ... . .. . . WYMAPEVIR---------------GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFH ---PAILDYLDYVFIRDPFYRPTLRDLLTK--F .. .| ... . .|| ||| ...| | NWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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| Kinase | DDB0231326.AA | Ciliate-E2 | 1836-1968 | 19 | 4.8e-16 | 51.55 | In-house | 148-296 (365) | Show / Hide |
Range on Protein: 1836-1968 Range on HMM: 148-296/365 Sequence Identity: 19% (36 aa) LNIFTNVLQ---------------SVQFLGDHK-INHFDIKCDNFLVHPLKKGTIEEDFWNQPTNDPNFAVCLADWGEAKVYTQD---------VEGYTT ..|.. .|| ...| . | | ||| .| |. ....|.| .| |..| . |. KYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF RN----------------------RGTEFIKSPEMLT-IAYASQKTRENFDRRKKVGSNTASDVWSLGCLFYELLTGDFLF . || ..||.| | | |. | ....|.||||...||.|.| . | -KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ--------QKQKGYDYKCDIWSLGVILYEMLFGKPPF |
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| Kinase | DDB0231326.AA | Ciliate-E2-Unclassified | 1836-1972 | 24 | 2.3e-14 | 46.28 | In-house | 146-274 (352) | Show / Hide |
Range on Protein: 1836-1972
Range on HMM: 146-274/352
Sequence Identity: 24% (38 aa)
LNIFTNVLQSVQFLGDHK-INHFDIKCDNFLVHPLKKGTIEEDFWNQPTNDPNFAVCLADWGEAKVYTQDVEGYTTRN---------------RGTEFIK
...| .|| ..| . | | |||..| |.. .| |. ....|.| .| | |... . |.. || .
KFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK---------------NYYIKIIDFGISKKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYM
----SPEMLTI-AYASQKTRENFDRRKKVGSNTASDVWSLGCLFYELLTGDFLFYDDD
.||.| | .| ..|.||||...||.|.| . ||| .
PQYTAPEVLQGQNYDHSKA-------------YKCDIWSLGVILYEMLFGYYPFYDNN
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| Kinase | DDB0231326.AA | AGC | 1920-1972 | 34 | 4.7e-12 | 25.96 | In-house | 275-309 (395) | Show / Hide |
Range on Protein: 1920-1972 Range on HMM: 275-309/395 Sequence Identity: 34% (19 aa) SPEMLTIAYASQKTRENFDRRKKVGSNTASDVWS--LGCLFYELLTGDFLFYDDD .||.| . | | || ||||.||.||| ||.|. APEIL--------------------YGKACDWWSFGLGCLMYEMLTGYPPFYGDN |
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| Kinase | DDB0231326.AA | SRPK | 1946-1968 | 56 | 5.3e-11 | 23.01 | In-house | 430-452 (554) | Show / Hide |
Range on Protein: 1946-1968 Range on HMM: 430-452/554 Sequence Identity: 56% (13 aa) NTASDVWSLGCLFYELLTGDFLF || |.||. |. .||.|||.|| NTPADIWSTACMAFELATGDYLF |
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| Kinase | DDB0231326.AA | TyrKc | 1730-2027 | 18 | 2e-08 | -86.44 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 1730-2027
Range on HMM: 1-280/280
Sequence Identity: 18% (60 aa)
FKDLKRVAKGAYGTVYKGTLGNDEGLEIAVKLMPVPKTIHDRCVLYDIFTEILIMDTF-RSDSRGCHMFDYGVDG-------ENYWIVMKSYKC-SLKEW
. .| ||.|.|||||. .. ||| . . . |. |. || . . .. . ... | ..||| . .||.
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD-
RLKQTLPFLELLPLLLNIFTNVLQSVQFLGDHKINHFDIKCDNFLVHPLKKGTIEEDFWNQPTNDPNFAVCLADWGEAKVYTQD-VEGYTTRNRGTEFIK
.|. . | .. ||.. . . . ..| .... | |. . | ||. . | .| | .. . | .| .. |
YLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH------------------TVKISDFGLSRDIYDDDQQG----ESKDYYRK
S---PEM--LTIAYASQKTRENFDRRKKVGSNTASDVWSLGCLFYELLTGDFLFYDDDWVKFFIRVTQPGQELITPERKSKVAN---------IPAILDY
. . | | . | .. .| .|.||||| | . .|..| | .. . .. .. . . . .| . .| ... .
KEHKGGKTMLPIRWMAP---ECINYGK---FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQI
LDYVFIRDPFYRPTLRDLLTKF
.|| ||| ... .|
MKQCWHEDPEDRPTFSEIHECF
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| Kinase | DDB0231326.AA | CMGC | 1946-1968 | 38 | 4.3e-08 | 21.71 | In-house | 313-343 (513) | Show / Hide |
Range on Protein: 1946-1968 Range on HMM: 313-343/513 Sequence Identity: 38% (12 aa) NTASDVWSLGCLFYELLTG--------DFLF .|. |.||.|| |.|..|| . || TTPIDMWSVGCIFAEMYTGYQSLIFRGKPLF |
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| Kinase | DDB0231326.AA | STE | 1730-1810 | 18 | 2e-06 | 18.82 | In-house | 34-149 (359) | Show / Hide |
Range on Protein: 1730-1810 Range on HMM: 34-149/359 Sequence Identity: 18% (22 aa) FKDLKRVAKGAYGTVYKGTLGN-----DEGLE---------IAVKLMPVPK-------------TIHDRCVLYDIFTEILIMDTFR--S----DSRGCHM ....... |||.|||||. . . | . .|.| |.. . . . . .| || || .. . ||.. WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF FDYGV--DGENYWIVM . .... ||.| KEGHNHKNDDELWICM |
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| Kinase | DDB0231326.AA | CAMK | 1838-1972 | 18 | 2e-06 | 16.21 | In-house | 184-338 (425) | Show / Hide |
Range on Protein: 1838-1972 Range on HMM: 184-338/425 Sequence Identity: 18% (32 aa) IFTNVLQSVQFLGDHKINHFDIKCDNFLVHPLKKGTI-----EEDFWNQPTNDPNFAVCLADWGEAKVYTQDVEGY----------------------TT .| ... |... .|.| | |.|..| |. .... | | |. . ..|.| |...... . . . YFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDE-IF-D----WNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMK RNRGTEFIKS-PEMLTI--------AYASQKTRENFDRRKKVGSNTASDVWSLGCLFYELLTGDFLFYDDD || . ||.| | .| . . ..|.||.|.. | .|.| . ||.|. TFCGTPEYMAAPEVLNGKGHCNMQNA-T---------DEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDC |
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| Kinase | DDB0231326.AA | ULK | 1949-1964 | 68 | 4e-06 | 17.44 | In-house | 237-252 (329) | Show / Hide |
Range on Protein: 1949-1964 Range on HMM: 237-252/329 Sequence Identity: 68% (11 aa) SDVWSLGCLFYELLTG .|.|||||.|||.|.| CDIWSLGCIFYEMLYG |
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| Kinase | DDB0231326.AA | ULK | 1949-1964 | 68 | 5e-06 | 17.4 | In-house | 233-248 (324) | Show / Hide |
Range on Protein: 1949-1964 Range on HMM: 233-248/324 Sequence Identity: 68% (11 aa) SDVWSLGCLFYELLTG .|.|||||.|||.|.| CDIWSLGCIFYEMLYG |
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| Kinase | DDB0231326.AA | CDK | 1730-1747 | 38 | 4.3e-05 | 12.07 | In-house | 253-270 (284) | Show / Hide |
Range on Protein: 1730-1747 Range on HMM: 253-270/284 Sequence Identity: 38% (7 aa) FKDLKRVAKGAYGTVYKG .. |... |.||.|||. YEKLEKIGEGTYGVVYKA |
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| Kinase | DDB0231326.AA | STE | 1946-1970 | 44 | 7.4e-05 | 13.23 | In-house | 246-270 (359) | Show / Hide |
Range on Protein: 1946-1970 Range on HMM: 246-270/359 Sequence Identity: 44% (11 aa) NTASDVWSLGCLFYELLTGDFLFYD .| .|.|||||. |..|| . | DTKCDIWSLGCTIIEMATGKPPWHD |
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| Kinase | DDB0231326.AA | CMGC | 1730-1748 | 36 | 8.1e-05 | 10.75 | In-house | 232-250 (513) | Show / Hide |
Range on Protein: 1730-1748 Range on HMM: 232-250/513 Sequence Identity: 36% (7 aa) FKDLKRVAKGAYGTVYKGT .. .|.. .|.||.|||.. YEIIKKIGEGTYGVVYKCR |
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| Kinase | DDB0231326.AA | CDK | 1950-1968 | 45 | 9.6e-05 | 10.93 | In-house | 204-225 (284) | Show / Hide |
Range on Protein: 1950-1968 Range on HMM: 204-225/284 Sequence Identity: 45% (10 aa) DVWSLGCLFYELLT---GDFLF |.||.|| |.|..| . || DMWSVGCIFAEMFTDVTRKPLF |
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| Kinase | DDB0231326.AA | ULK | 1730-1760 | 26 | 0.00032 | 10.95 | In-house | 35-68 (324) | Show / Hide |
Range on Protein: 1730-1760 Range on HMM: 35-68/324 Sequence Identity: 26% (9 aa) FKDLKRVAKGAYG-TVYKGT-LGNDE-GLEIAVK . .. ||..| .||||. ... . .|.| YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACK |
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| Kinase | DDB0231326.AA | AGC | 1730-1745 | 50 | 0.000385 | 5.02 | In-house | 248-263 (395) | Show / Hide |
Range on Protein: 1730-1745 Range on HMM: 248-263/395 Sequence Identity: 50% (8 aa) FKDLKRVAKGAYGTVY |. || . ||..|.|| FEFLKVIGKGSFGKVY |
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| Kinase | DDB0231326.AA | CAMK | 1735-1784 | 15 | 0.000714 | 7.57 | In-house | 267-351 (425) | Show / Hide |
Range on Protein: 1735-1784 Range on HMM: 267-351/425 Sequence Identity: 15% (13 aa) RVAKGAYGTVYKGTLGNDEGLE-----------IAVKLMPVPKTIHD------------------------RCVLYDIFTEILIM .|..|.|.... |. |.| |.| .. | . . . .. || || TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIM |
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| Kinase | DDB0231326.AA | ULK | 1730-1748 | 36 | 0.001064 | 8.89 | In-house | 122-140 (329) | Show / Hide |
Range on Protein: 1730-1748 Range on HMM: 122-140/329 Sequence Identity: 36% (7 aa) FKDLKRVAKGAYGTVYKGT . .. ||..|.||||. YCLNHCLGKGSFGKVYKGR |
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| Kinase | DDB0231326.AA | STE | 2004-2028 | 35 | 0.006806 | 6.2 | In-house | 332-359 (359) | Show / Hide |
Range on Protein: 2004-2028 Range on HMM: 332-359/359 Sequence Identity: 35% (10 aa) DYLDYVFIRDPFYRPTLRDLLT---KFI | .. ...|| ||| .|| .|| DFINKCLQKDPNKRPTASQLLKSEHPFI |
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| Kinase | DDB0231326.AA | Ciliate-E2-Unclassified | 1730-1746 | 41 | 0.015108 | 4.68 | In-house | 266-282 (352) | Show / Hide |
Range on Protein: 1730-1746 Range on HMM: 266-282/352 Sequence Identity: 41% (7 aa) FKDLKRVAKGAYGTVYK .| .| .|..|.||| YKIIKQIGQGGFGKVYK |
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| DSPc | DDB0231326.AA | DSPc | 2130-2268 | 29 | 1.3e-27 | 98.97 | SMART | 1-172 (172) | Show / Hide |
Range on Protein: 2130-2268 Range on HMM: 1-172/172 Sequence Identity: 29% (51 aa) RPSKVASFMYISSFNPSM--NKNMLINEYQITHIINCT-GSPN-----------------AFPDHFEYLHLQ-LHD-------QPHQDITQSLSLAFDFI ||.. |..| . .| |. .| ...|||.||.| . |. .. ||.|.|.. ..| . ..|.| .. ..||| GPSEITPHLYLGSYPHHMEPNPCFLK-KHNITHVINVTMECPWNFHHCQKNDMHYTNEWIYHNSHFQYMHIPMIDDIYYHIRWNHCTNISQYFPEVYDFI RDAIVHHGKVLICSDKGVSRSSALAIGYFMDSRSISYFEAFILV-----RDCR-YIISPNTGFVEQLCRWGKQ |.. .||||. |.||| .|.| | |.....|| .|. .| .. | ||.|| .|. ||| | .. HDCRQKGGKVLVHCQAGISRSATLCIAYLMKYMNMSYNDAYHFVYIYHIKQRRCPIICPNFNFWHQLCEWERK |
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| DSPc | DDB0231326.AA | DSPc | 2138-2268 | 34 | 2.1e-26 | 93.74 | Pfam | 1-151 (151) | Show / Hide |
Range on Protein: 2138-2268 Range on HMM: 1-151/151 Sequence Identity: 34% (53 aa) MYISSFNPSM-NKNMLINEYQITHIINCT-GSPN---AFPDHFEYLHLQ-LHD---------QPHQDITQSLSLAFDFIRDAIVHHGKVLICSDKGVSRS |..|. .| .. .| . ..|||.|||| || . ||.|.... .|| . ..|.| .. |.|||.|.. .||||. |.||| LYLGSYPHHMADPAFLQK-HGITHVINCTMECPNNWFYHNSHFHYMWIPHVHDHIHYYHIHWNHCTNISQYFPMATDFIDDCRQKGGKVLVHCQAGISRS SALAIGYFMDSRSISYFEAFILV-----RDCR-YIISPNTGFVEQLCRWGKQ .|.| | |..| .|| ||. .| .. | .||||..| ||| ...| ACLCIAYLMKYRNMSYNEAYDFVYIYHMKQRRCPMISPNMNFWRQLCEYERQ |
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