Gene 15779 (Tetrahymena)

15779

Species: Tetrahymena
Alias: 720, 15779, TTHERM_01365640, PreTt15779, 349.m00006
External Links: Tetrahymena Genome Database (TGD)
Annotation: Secondary Group: Other, Secondary Family: Ciliate_C8_Cterm,

Classification

Group: Other
Family: Ciliate-C8
Subfamily: C8

Sequence

Name Sequence Type Origin Length Description Download
15779.AA Protein None 1349 None Fasta, JSON
15779.kin_dom Protein Kinase Domain None 218 None Fasta, JSON
15779.kin_dom2 Protein Kinase Domain None 203 None Fasta, JSON
15779.NA RNA None 4050 None Fasta, JSON

Protein domain

Protein domains of 15779.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 15779.AA C8 42-256 60 2.5e-118 399.41 In-house 1-226 (226) Show / Hide 
Range on Protein: 42-256
Range on HMM: 1-226/226
Sequence Identity: 60% (136 aa)

FQKYEYLSSGAYSLVLKAYNSKQKRQVALKFLGSSNQEENDGIESLKKEYEMLQKFSQSQFLVNVYDCFYLMEEQDDEDEDGNDIIVQTGVKSFFVMEME
|....|||.|||..||||.|.|..|...|||. ..|......|||..|||||.|.|.|..|.||.|||||.|.|. .|....|..|||| .||.||||||
FNNFQYLSFGAYGMVLKAKNVKDNREIVLKFQKCQNKQDIQNIESIMKEYEMPQVFQQYDFYVNEYDCFYEMYEVFEEEKCSNEKIVQTEEKSCFVMEME

LCEKNLKQLFDILRKEQVPPSKELKEIIAIQMIEGLNNLHVKNIMHRDIKPQNFLVCTSQEYGFQIKLCDLGFASAVSKSKS-FVSKK----GTDSYFAP
|||.|||||.| .|..|...||| |||||||||.|.|..|.||||||||||.|||||..|.|||.|||||.||||.|||.|| . |||    ||. ||||
LCEQNLKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAP

EVEEG------QSRIQSDLFSLGLVL
|.|..      |.||||||||.||||
EIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase 15779.AA Ciliate-C8 51-256 55 1.4e-116 393.63 In-house 1-238 (238) Show / Hide 
Range on Protein: 51-256
Range on HMM: 1-238/238
Sequence Identity: 55% (133 aa)

GAYSLVLKAYNSKQKRQVALKFLGSSNQEENDGIESLKKEYEMLQKFSQSQFLVNVYDCFYLMEEQDDEDEDGNDIIVQTGVK---SFFVMEMELCEKN-
||...||||.|.||.|.|||||. ..|.......|...|||||...|.|..|.|.||||||||||...||.||||.|||| .|   ||||||||.|..| 
GAFGMVLKAQNKKQNRKVALKFRECVNKIQKNQMEHEIKEYEMIMQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKKSFFVMEMEKCQQNC

-LKQLFDILRKEQVPPSKELKEIIAIQMIEGLNNLHVKNIMHRDIKPQNFLVCTSQEYGFQIKLCD------LGFASAVSKSKS-FVSKK--GTDSY---
 |||.|| .||.|..||.. |||||||||...|.||..|||||||||.||||| .|.|...|||||      .||||...|.|| ..|||  ||| |   
NLKQYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEM

--------FAPEVEEGQSRIQSDLFS-------LGLVL
        ||||||..|||||||.||       .||||
YFCGNWGYFAPEVEKKQSRIQSDIFSKKSDSYSVGLVL
Kinase 15779.AA C2 51-269 39 6.7e-70 237.93 In-house 1-245 (245) Show / Hide 
Range on Protein: 51-269
Range on HMM: 1-245/245
Sequence Identity: 39% (96 aa)

GAYSLVLKAYNSKQKRQVALKFLGSSNQEENDGIESLKKEYEMLQKFSQSQFLVNVYDCFYLMEE-QDDEDEDGNDIIVQTGV--------KSFFVMEME
|| .|||||.| ||.|.||||     .. .  | ... |||....... . ....||..||| .. ..||||| ......           |.|.|.|.|
GAFGLVLKAFNKKQNRHVALKIQ-ECQSNDINGMHEVQKEYGIMRQCQNMPYIIKVYNYFYLTVNKKEDEDEDNDEEEKEQENIKKQKNEKKIFVVYEQE

LCEKNLKQLFDILRKEQVPPSKELKEIIAIQMIEGLNNLHVKNIMHRDIKPQNFLVCTSQEYGFQIKLCD----------LGFASAVSKSKS--FVSK-K
 |..|||| |. .||..  |... |.|.||||. . | || ..| ||||||.|||.  .|.    |||||          . |||.....||   .|| |
FCQGNLKQYFNRCRKQNSYPCQQMKMIMAIQMMDSINYLHRFDIVHRDIKPSNFLYQFDQQGIPTIKLCDYHIQYQKKCDFDFASKLKYNKSRIHFSKFK

GTDSY----FAPEVEEGQSRIQSDLFS-LGLVLLELDNFNTLNKNW
.| .|    |||||...  . .||||| .|.||||||| .. . . 
WTQQYYQHIFAPEVYQNIYKKNSDLFSTVGYVLLELDNMQQYTICC
Kinase 15779.AA CMGC 42-220 16 2.3e-26 82.86 In-house 1-256 (513) Show / Hide 
Range on Protein: 42-220
Range on HMM: 1-256/513
Sequence Identity: 16% (42 aa)

FQKYEYLSSGAYSLVLKAYN--------------SKQKRQVALKFLGSSNQEENDGI---------ESLKKEYEMLQKFS----------------QSQF
... ... .|.|. | |...               . ...||.| . .   .|...           .   | ..|....                .   
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

LVNVYDCFYLMEEQDDEDEDGNDIIVQTGVKSFFVMEMELCEKNLKQLFDILRK-----EQVPPSKEL------------KEIIA------IQMIEGLN-
.|. ||.||  ... .|.|| . |  .      . . .|.....|.|. .  ..      ..| |               .  .        |...||. 
IVKLYDIFYHKNSDGNEYEDKHII--SQ-HFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKL

-NLHVKN--IMHRDIKPQNFLVCTSQEY----------------GFQIKLCDLGFASAVSK
  .| ..  |.|||.||.| |..   |.                 ...|.|| |.| ....
KYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHP
Kinase 15779.AA Pkinase 42-259 22 9.5e-26 92.13 Pfam 1-205 (293) Show / Hide 
Range on Protein: 42-259
Range on HMM: 1-205/293
Sequence Identity: 22% (52 aa)

FQKYEYLSSGAYSLVLKAYNSKQKRQVALKFLGSSNQEENDGIESLK-KEYEMLQKFSQSQFLVNVYDCFYLMEEQDDEDEDGNDIIVQTGVKSFFVMEM
... . . ||... | |... .  ..||.| .  ......  .. ..  | ...... .. . |  ||.|.                     |.   | |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--------------------KDHIYMVM

ELCEKN--LKQLFDILR--KEQVP--PSKELKEIIAIQMIEGLNNLHVKNIMHRDIKPQNFLVCTSQEYGFQIKLCDLGFASA--VSKSKSFVSKKGTDS
|.||.   .  |||...  .. .   . .|.| ..  |...||. .| ..|.|||.||.|.|.    . .  .|.|| |.|      ..  . .  ||  
EYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMY-QILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPW

YFAPEV--EEGQSRIQSDLFSLGLVLLEL
| ||||  .       .| .|.|..| |.
YMAPEVIRGGQYYGPKVDMWSCGCILYEM
Kinase 15779.AA STE 42-259 18 1.5e-23 80.09 In-house 1-261 (359) Show / Hide 
Range on Protein: 42-259
Range on HMM: 1-261/359
Sequence Identity: 18% (52 aa)

FQKYEYLSSGAYSLVLKAYNS------KQKRQ---------VALKFLGSSNQE-ENDG--------------IESLKKEYEMLQKFSQ-SQFLVNVYDCF
... | . .||.  | ||.|       | ...         .| | .  .|.. ..                .....|| ....|... ... |. |.|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

YLMEEQDDEDEDGNDIIVQTGVKSFFVMEMELCE-KNLKQLFD-ILRKEQVPPSKE-------LKEI--IAIQMIEG-LNNLHVKNIMHRDIKPQNFLVC
.   .              .. ..   . ||...   | .. .    . .  ...         ..|  |. | ..| |. || ..|.||||||.| |. 
FKEGHN-------------HKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-

TSQEYGFQIKLCDLGFASAVSK-----------------SKSFVSKKGTDSYFAPEVEEG-QSR------IQSDLFSLGLVLLEL
        .|||| |... ...                 ..   .  ||  . |||| .. ..       ...|  |||....|.
--------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEM
Kinase 15779.AA CAMK 47-238 15 4.1e-22 67.4 In-house 1-291 (425) Show / Hide 
Range on Protein: 47-238
Range on HMM: 1-291/425
Sequence Identity: 15% (46 aa)

YLSSGAYSLVLKAYNSKQK------------RQVALKF------------------------LGSSNQEENDGIES-LKKEYEMLQKFS------QSQFL
 | .|... | .... . .            ..|| |.                         .........  .  ...|.|...| .      .   .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VNVYDCFY------------LMEEQDDEDEDGNDIIVQTGVKSFFVMEM---ELCEKN--LKQLFDILRKE-----------QVPPSKELKEIIAI----
.. |. .               . |           |    .....| |   |.|.    .  ||| ...             |  .. ..|  |     
IKLYEVYEDPHYFKNTNDYET-SKQ-----------VF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFR

QMIEGLNNLHVKNIMHRDIKPQNFLVCTSQEYG-------------FQIKLCDLGFASAVSKSK------------------------SFVSKKGTDSYF
|...... .| .||.|||.|| | |.... .               ..||..| |||  . ...                         .    || .| 
QICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYM

A-PEV
| |||
AAPEV
Kinase 15779.AA Ciliate-E2 169-259 25 1.9e-21 70.36 In-house 165-289 (365) Show / Hide 
Range on Protein: 169-259
Range on HMM: 165-289/365
Sequence Identity: 25% (34 aa)

IAIQMIEGLNNLHVKN-IMHRDIKPQNFLVCTSQEYGFQIKLCDLGFASAVSKS----------KSFVSKK-----------------------GTDSYF
.. ..|..|. || || |.||||||.| |.         ||..|.|..  ....          | .   |                       ||  | 
YIACIILALEYLHSKNNIIHRDIKPENILF---------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYM

APEVEEGQSR----------IQSDLFSLGLVLLEL
|||. .|..            ..|..||| .| |.
APEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM
Kinase 15779.AA S_TKc 42-323 21 1.3e-20 75.74 SMART 1-231 (231) Show / Hide 
Range on Protein: 42-323
Range on HMM: 1-231/231
Sequence Identity: 21% (64 aa)

FQKYEYLSSGAYSLVLKAYNSKQKRQVALKFLGSSNQEENDGIESLKKEYEMLQKFSQSQFLVNVYDCFYLMEEQDDEDEDGNDIIVQTGVKSFFVMEME
... . . .||.. | |... | .|.||.| .           |....| ..|.|  .  ..|. ||.|.                      ... | ||
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD---------------------DHLYMVME

LCEKNLKQLFDILRKEQVP------PSKELKEIIAIQMIEGLNNLHVKNIMHRDIKPQNFLVCTSQEYGFQIKLCDLGFASAVSKSKSFVSKKGTDSYFA
.|. .|  |||...| . .      |  . . ... |....|. .| ..|.|||.||.| |...      .||.|| |.|  .       .  ||  | |
YCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMY-QICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL------TTFCGTPWYMA

PEVEEGQSRIQSDLFSLGLVLLELDNFNTLNKNWIDTKIRYYLFNGEKIPEEKYQIDKNSNIYKIAQICLKPKYLDRTTAGELLS--------QII
|||  | ..  .|  |.| .| |.    ..     . ..   .                .    . . ||.    .| || |.|         . .
PEVL-GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 15779.AA Ciliate-E1 135-250 24 1.1e-19 61.06 In-house 71-202 (202) Show / Hide 
Range on Protein: 135-250
Range on HMM: 71-202/202
Sequence Identity: 24% (33 aa)

FFVMEMELCEKNLKQLFD---------ILRKEQVPPSKELKEIIAIQMIEGLNNLHVKNIMHRDIKPQNFLVCTSQEYGFQIKLCDLGFAS-AVSKSKSF
...  .|.|...||. ..         .....|   . . |. |..|.|.||. || .||.|||||||| |.. . .| ..    |.| ..   ..... 
ICIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYC----DFGISKFLKNNQNQQ

VSKKGTDSYFAPEVE--------EGQ--SRIQSDLF
. .||  .|..|. .        . .    ..||..
CQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY
Kinase 15779.AA TKL 169-259 21 5.9e-18 61.25 In-house 137-282 (364) Show / Hide 
Range on Protein: 169-259
Range on HMM: 137-282/364
Sequence Identity: 21% (31 aa)

IAIQMIEGLNNLHV--------KNIMHRDIKPQNFLVCTSQE----------YGFQIKLCDLGFASAVSKSKS--------------------FVSKKGT
.|...  |.| ||         ..| |||.|..| ||    .          .   .|.||.|..  .|.|..                      .. ||
WALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGT

DSYFAPEV-----------------EEGQSRIQSDLFSLGLVLLEL
  . ||||                 ....   ..| .| |.|| |.
PRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEI
Kinase 15779.AA TKL-Unique 169-259 32 1.4e-16 55.13 In-house 115-221 (290) Show / Hide 
Range on Protein: 169-259
Range on HMM: 115-221/290
Sequence Identity: 32% (35 aa)

IAIQMIEGLNNLHVKN--IMHRDIKPQNFLVCTS-QEYGFQIKLCDLGFASAVSKS-KSFVSKK---------GTDSYFAPEVEEG---QSRIQSDLFSL
.||..  |...|| ..  |.|||.|..||||     .  ..||.|| |..   ||. |.... .         |.  . |||| ..   |  ..|| .| 
MAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSF

GLVLLEL
| || |.
GIVLWEI
Kinase 15779.AA Ciliate-E1 48-112 20 6.3e-08 22.36 In-house 1-66 (202) Show / Hide 
Range on Protein: 48-112
Range on HMM: 1-66/202
Sequence Identity: 20% (14 aa)

LSSGAYSLVLKAYNSKQK-RQVALKFLGSSNQEENDGIESLKKEYE-MLQKFSQSQFLVNVYDCFYL
...| .|.|.||.. ... .|||.|.     ... . .....|||  ... | . . .....|....
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKI
Kinase 15779.AA Ciliate-E2 42-116 13 3e-06 17.53 In-house 1-107 (365) Show / Hide 
Range on Protein: 42-116
Range on HMM: 1-107/365
Sequence Identity: 13% (14 aa)

FQKYEYLSSGAYSLVLKAYNSKQKRQVALK-----------------FLGSSNQEENDGIESLKKEYEMLQ---------------KFSQSQFLVNVYDC
. . . . .|... | |. . |...|.|.|                 ..   .. ....||..|.|  ...               .. .. .... |.|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FYLMEEQ
|. . ..
FQEKDDN
Kinase 15779.AA C8 403-604 47 5.7e-100 338.43 In-house 1-226 (226) Show / Hide 
Range on Protein: 403-604
Range on HMM: 1-226/226
Sequence Identity: 47% (108 aa)

SNNFQILSFGNFGMVLATKKAKLDNKEIVLKIQKIEDEQLIQNEISIMQKLKEPLVVQLYDSYIIENKLVHDRYSVFELEKCS-----------CSLDE-
.||||.||||..||||..|..| ||.|||||.||....| |||..|||.....|.|.|.||.|..|... ...|.|||.||||           |...| 
FNNFQYLSFGAYGMVLKAKNVK-DNREIVLKFQKCQNKQDIQNIESIMKEYEMPQVFQQYDFYVNEYDCFYEMYEVFEEEKCSNEKIVQTEEKSCFVMEM

----------YLERQNKEGQLNEENKFQMAIQIIDSVNYIHQFNIIHRDIKPENFLVYLDGKQA-KIKLCDFGLSAQIPDNQDSIQTIER--IGNFGYSA
          |.||.||..|...|.|...|||.||.|||||..||.||||||.||||.||...  .|||||||...|...|...||...   .|...|.|
ELCEQNLKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFA

PEILNKNDNELKFYTKKSDSYSVGLLL
|||..|.||..|.|...||..||||.|
PEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase 15779.AA Ciliate-C8 412-604 39 7.9e-97 327.99 In-house 1-238 (238) Show / Hide 
Range on Protein: 412-604
Range on HMM: 1-238/238
Sequence Identity: 39% (93 aa)

GNFGMVLAT------KKAKLDNKEIVLKIQKIEDEQLIQNEISIMQKLKEPLVVQLYDSYIIENKLVHDR-----------------YSVFELEKCS--C
|.|||||..      .| .|...|.|.||||...|..|.....|||....|.|||.||....... . ..                 ..|.|.|||.  |
GAFGMVLKAQNKKQNRKVALKFRECVNKIQKNQMEHEIKEYEMIMQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKKSFFVMEMEKCQQNC

SLDEYLER-QNKEGQLNEENKFQMAIQIIDSVNYIHQFNIIHRDIKPENFLVYLD-GKQAKIKLCD------FGLSAQIPDNQD---------SIQTIER
.|..|..| ..|....... |...|||.||||||.|.|||.||||||.||||..| ..|  |||||      ||...|.|.|..         ..|.|| 
NLKQYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEM

--IGNFGYSAPEILNK-NDNELKFYTKKSDSYSVGLLL
  .||.||.|||...| .........||||||||||.|
YFCGNWGYFAPEVEKKQSRIQSDIFSKKSDSYSVGLVL
Kinase 15779.AA C2 412-617 28 2.8e-43 145.72 In-house 1-245 (245) Show / Hide 
Range on Protein: 412-617
Range on HMM: 1-245/245
Sequence Identity: 28% (72 aa)

GNFGMVLATKKAKLDNKEIVLKIQKIED-----EQLIQNEISIMQKLK-EPLVVQLYDSYIIENKLVHD-------------R----------YSVFELE
| ||.|| .   | .|....||||....     .. .|.|..||....  |.....|...    .   |             .            |.|.|
GAFGLVLKA-FNKKQNRHVALKIQECQSNDINGMHEVQKEYGIMRQCQNMPYIIKVYNYFYLTVNKKEDEDEDNDEEEKEQENIKKQKNEKKIFVVYEQE

KCSCSLDEYLERQNKEG-QLNEENKFQMAIQIIDSVNYIHQFNIIHRDIKPENFLVYLDGKQA-KIKLCD----------FGLSAQIPDNQDSIQTIERI
.|.. |  |..|. |.  ..... | .||||..||.||.|.|.|.||||||.|||. .| ..   |||||          |  .  .. |.  | . .  
FCQGNLKQYFNRCRKQNSYPCQQMKMIMAIQMMDSINYLHRFDIVHRDIKPSNFLYQFDQQGIPTIKLCDYHIQYQKKCDFDFASKLKYNKSRIHFSKFK

GNFGY----SAPEILNKNDNELKFYTKKSDSYS-VGLLLALLDNYQDLKTNT
.   |    .|||.      . . | |.|| .| ||. |  ||| |    . 
WTQQYYQHIFAPEV------YQNIYKKNSDLFSTVGYVLLELDNMQQYTICC
Kinase 15779.AA CAMK 408-604 19 1.1e-34 108.65 In-house 1-324 (425) Show / Hide 
Range on Protein: 408-604
Range on HMM: 1-324/425
Sequence Identity: 19% (62 aa)

ILSFGNFGMVLATKKAKLDN-----------KEIVLKI---QKIE----------------------------DEQLIQNEISIMQK-------LKEPLV
.|  |.|| |   .  .  .           ..   ||   .|.                             |.. ...||.||.|       |. | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLYDSYI------------IENK-LVHD--RYSVFEL---EKCSC-----SLDEYLERQNK------------EGQLNEENKFQMAIQIIDSVNYIHQF
..||. |               .|  . .  .. .. .   | ||       | .|. .. .            .| ..|.   ..  ||.. |.|.|. 
IKLYEVYEDPHYFKNTNDYET-SKQVF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSH

NIIHRDIKPENFLVYLDG--------------KQAKIKLCDFGLSAQIPDNQDSI---------------------QTIERIGNFGYSA-PEILNKN---
||.|||.|||| |.  ..              ....||..|||...........                         .. |  .| | ||.||..   
NIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

------DNELKFYTKKSDSYSVGLLL
      |.| . |..|.|  |.| .|
NMQNATDEEKPYYGPKCDMWSCGVIL
Kinase 15779.AA S_TKc 403-676 23 1.4e-31 112.18 SMART 1-231 (231) Show / Hide 
Range on Protein: 403-676
Range on HMM: 1-231/231
Sequence Identity: 23% (69 aa)

SNNFQILSFGNFGMVLATKKAKLDNKEIVLKIQKIEDEQLIQNEISIMQKLKEPLVVQLYDSYIIENKLVHDRYSVFELEKCSC---SLDEYLERQNKEG
    ...  | || |   .. | ....  .|| |    . |..||.|..| . | .|.|||..       .. | |.|.  |.    .| .|.......|
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVMEY--CDGDLGDLFDYIKKRGRHG

Q---LNEENKFQMAIQIIDSVNYIHQFNIIHRDIKPENFLVYLDGKQAKIKLCDFGLSAQIPDNQDSIQTIERIGNFGYSAPEILNKNDNELKFYTK-KS
    ..|     .. ||.. ..|.|. .|||||.|||| |.        ||.|||||..|.            .|   | |||.|         |.| |.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL---------TTFCGTPWYMAPEVL--------GYGKCKC

DSYSVGLLLALLDN----YQDLKTNTTSIFSLMTQKQLDKPFEKSNIQINKNSEIYKFINLLVVSDSDQRASLYDIVK-QSD---ETFF
| .|.| .|. .      ..    .   .| ..                   .|   ||. . . | ..| .  .. . ..|     .|
DWWSCGCILYEMLCGYPPFP----QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 15779.AA Ciliate-E1 409-598 26 4.2e-30 95.33 In-house 1-202 (202) Show / Hide 
Range on Protein: 409-598
Range on HMM: 1-202/202
Sequence Identity: 26% (56 aa)

LSFGNFGMVLATKKAKLDNKEIVLKIQKIEDEQ-------LIQNEISIMQKLKEPL-VVQLYDSYIIENKLVHDRYSVFELEKCSCSLDEYLE-------
.. | |..|.  |. .  .... .||..... .       .|.....||. .|.   ..|..| ..|.. ...    .. .|.|.||| .||.       
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYIC----IIIFECCCCSLKDYLQNHNRLEY

---RQNKEGQLNEENKFQMAIQIIDSVNYIHQFNIIHRDIKPENFLVYLDGKQAKIKLCDFGLSAQIPDNQDSIQTIERIGNFGYSAPEILNK---NDNE
    |....|.....| |...|.|| ....||.|||||||||.| |.. . .. ..   |||.| ..  ||.. |. ..     |. || .|    . |.
WQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQ-GNYVYC--DFGISKFLKNNQNQ-QCQYKGYTHYYYPPEQYNCPEQEHNK

LKFYTKKSDSY
 . ...||| |
NQKINYKSDIY
Kinase 15779.AA STE 404-604 22 5.3e-27 92.45 In-house 1-258 (359) Show / Hide 
Range on Protein: 404-604
Range on HMM: 1-258/359
Sequence Identity: 22% (60 aa)

NNF-QILSFGNFG-MVLATKKAKL-------------DNKEIVLKIQKI--------------------EDEQLIQNEISIMQKLK--EPLVVQLYDSYI
  . ...  |.||  ..| .. .               .. .  |. ..                    |..| |..||.||.|..   | .|. |..|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

IEN--KLVHDRYSVFELEKCSC-SLDEYLE-RQNKEGQLN----------EENKFQMAIQIIDS-VNYIHQFNIIHRDIKPENFLVYLDGKQAKIKLCDF
 |.  .  .|   .. .| ..  |||. .. .  . ..||          |.    .. ||.    .|.|. .|||||||| | |.        .|||||
KEGHNHKNDDELWIC-MEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--------VKLCDF

GLSAQIPDNQDSI--------------QTIERIGNFGYSAPEILNKNDNE-LKFYTKKSDSYSVGLLL
|...|. |. ..|              ..   .|   . |||....|..   | |. |.| .|.|...
GVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTI
Kinase 15779.AA Ciliate-E2 403-604 21 1.2e-26 88.44 In-house 1-286 (365) Show / Hide 
Range on Protein: 403-604
Range on HMM: 1-286/365
Sequence Identity: 21% (64 aa)

SNNFQILSFGNFG-----MVLATKKA-----------------KLDNKEIVLKIQKIEDEQLIQNEISIMQ----------------KLKEPLVVQLYDS
 .  ... .||||      |  ..|                  | ..|.. .||.|  . . | .||.||.                .|. | ....|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YIIENK----LVHDRYSVFELEK-----CSCSLDEYLERQNKEGQLNEENKFQMAIQIID---------------SVNYIHQFN-IIHRDIKPENFLVYL
.. ...    || . ..  .|..     . ... |    . . ....|.   ..  ||..                ..|.|. | |||||||||| |.  
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIE--K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--

DGKQAKIKLCDFGLSAQIPDNQD--------SIQTIER----------------------IGNFGYSAPEILNKNDNE----LKFYTKKSDSYSVGLLL
      ||..||||| .. |...         . .  .                      .|. || ||||||. ...     | |..|.| .|.| .|
------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL
Kinase 15779.AA Pkinase 403-605 26 7.6e-25 88.94 Pfam 1-203 (293) Show / Hide 
Range on Protein: 403-605
Range on HMM: 1-203/293
Sequence Identity: 26% (59 aa)

SNNFQILSFGNFGMVLATKKAKLDNKE--IVLKIQKIEDEQLIQN-------EISIMQKLKEPLVVQLYDSYIIENKLVHDRYSVFELEKCSC-----SL
    ...  |.|| |   .|..  . .   ..|| | ..|   ..       ||.||..|. | .|.|||..        ...  . .| | .     .|
YHIGRKIGSGSFGCV---YKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDL

DEYLERQNKEGQL--NEENKFQMAIQIIDSVNYIHQFNIIHRDIKPENFLVYLDGKQ-AKIKLCDFGLSAQIPDNQDSIQTIERIGNFGYSAPEILNKND
 .|...  ..| .   |.    .. ||.  ..|.|. .|||||.||||.|.  .|   |..|.|||||..|.  .  .  .  . |  .| |||...   
FDYIST-WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIR---

NELKFYTKKSDSYSVGLLLA
 . . |..|.| .|.|..|.
-GGQYYGPKVDMWSCGCILY
Kinase 15779.AA TKL 487-604 23 4.6e-23 79.9 In-house 124-279 (364) Show / Hide 
Range on Protein: 487-604
Range on HMM: 124-279/364
Sequence Identity: 23% (39 aa)

S-LDEYLERQNKEGQLNEENKFQMAIQIIDSVNYIHQFN--------IIHRDIKPENFLVYLDGK-----------QAKIKLCDFGLSAQIP---DNQDS
| |. ..           . ....|..|   .|| |. |        |||||.|..| ||  ...           . ..|.||||||  .    ...|.
SLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDT

I--------------QTIERIGNFGYSAPEILNKNDNELKF-----------YTKKSDSYSVGLLL
               .|. ..|.... |||.|....|  .            |..|.| || |..|
MTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVL
Kinase 15779.AA CMGC 406-554 16 5.7e-22 68.16 In-house 1-251 (513) Show / Hide 
Range on Protein: 406-554
Range on HMM: 1-251/513
Sequence Identity: 16% (42 aa)

FQILS---FGNFGMVLATKKAKLD-------------NKEIVLKIQKIEDEQLIQ---------------NEISIMQKLK-----------------EPL
..|..    | .|.|   .  . .             |... .|. | .    .|                ||.|...|.                 .. 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VVQLYDSYIIEN------------KLVHDRYSVFELEKCSCSLDEYLERQN--KEG-QLNEENKFQ---------------MA------IQIIDSVN--Y
.|.|||..  .|            .. |...  .  | . ..| .|.....  . | . .. .  .               .        ||. ...  |
IVKLYDIFYHKNSDGNEYEDKHIISQ-HFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKY

IHQFN--IIHRDIKPENFLVYLDGKQ-----------------AKIKLCDFGLS
.|. .  |||||.|||| |.  ...                   ..|.|||||.
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLA
Kinase 15779.AA TKL-Unique 487-599 34 4.7e-21 71.12 In-house 86-213 (290) Show / Hide 
Range on Protein: 487-599
Range on HMM: 86-213/290
Sequence Identity: 34% (46 aa)

SLDEYLER-------QNKEGQLNEENKFQMAIQIIDSVNYIHQFN--IIHRDIKPENFLVYLDGK----QAKIKLCDFGLSAQIP-DNQDSIQTI-----
||...| .        |..  || ... .|||.| .  .|.|  .  |||||.|. ||||  | .    . .||.||||||     .|. .. ..     
SLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLV--DNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRN

-ERIGNFGYSAPEILNKNDNELKFYTKKSDSYS
 .|.|.| ..|||.|. |    . |..||| ||
QTRCGSFRWMAPEVLRMNF---CQYSEKSDVYS
Kinase 15779.AA TyrKc 403-671 20 2.1e-10 -54.61 SMART 1-280 (280) Show / Hide 
Range on Protein: 403-671
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

SNNFQILSFGNFGMVLATKKAKLDNKEIVLKIQKIEDEQLIQNEISIMQKL--KEPLVVQLYDSYIIENK-----LVHDRYSVFELEKCSCSLDEYLERQ
    ..|  |.|| |    |....  .   |  | . .. . .|..|| ||  . | .|.||   ..  .      ..  . |.|. .   .|..|| . 
ITLGKKLGEGAFGEVY---KGTWK-IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLY--GVCTQQGRNFMYIEPLMIVMEYMPH-GDLKDYLRKH

NKEGQLNEENKFQMAIQIIDSVNYIHQFNIIHRDIKPENFLVYLDGKQAKIKLCDFGLSAQIPDN------QDSIQT----IER-IGNFGYSAPEILNKN
 ..  |. . . ....|| .  .|.|. |.||||.   | ||  ..    .| .|||||  | |       .| . .     ..        ||| .   
RPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI---

DNELKFYTKKSDSYSVGLLL----ALLDNYQDL-----KTNTTSIFSLMTQKQLDKPFE----KSNIQINKNSEIYKFINLLVVSDSDQRASLYDIVKQS
    . .| ||| .| | ..     . .          ..|.  |  ... . ...| .     .       .|.|. .      | ..| .  .|... 
--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF---VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
LRR_RI 15779.AA LRR_RI 710-737 21 0.001928 17.7 SMART 1-28 (28) Show / Hide 
Range on Protein: 710-737
Range on HMM: 1-28/28
Sequence Identity: 21% (6 aa)

NYNIVTIDLEENSIRDADAKDLATGIAQ
| .. ...|. | . |. .. |. |...
NCSLRELWLSNNKLGDEGCRQLCEGLKH
LRR_RI 15779.AA LRR_RI 746-767 36 0.021628 10.29 SMART 7-28 (28) Show / Hide 
Range on Protein: 746-767
Range on HMM: 7-28/28
Sequence Identity: 36% (8 aa)

LHLSQNSIGAQGAKDLATGIAQ
|.||.| .|. |.. |. |...
LWLSNNKLGDEGCRQLCEGLKH
LRR_RI 15779.AA LRR_RI 770-797 28 0.062649 7.03 SMART 1-28 (28) Show / Hide 
Range on Protein: 770-797
Range on HMM: 1-28/28
Sequence Identity: 28% (8 aa)

NITNLMLDLQGNSIGAQGAKYLATGISL
| . . |.|..| .|. |.. |. |.. 
NCSLRELWLSNNKLGDEGCRQLCEGLKH
LRR_RI 15779.AA LRR_RI 800-827 28 0.002247 17.23 SMART 1-28 (28) Show / Hide 
Range on Protein: 800-827
Range on HMM: 1-28/28
Sequence Identity: 28% (8 aa)

NITNLTLDLQGNSIGDVGAKHLSTVIEQ
| . ..|.|..| .|| |...|. ....
NCSLRELWLSNNKLGDEGCRQLCEGLKH
LRR_RI 15779.AA LRR_RI 830-857 32 0.001299 18.91 SMART 1-28 (28) Show / Hide 
Range on Protein: 830-857
Range on HMM: 1-28/28
Sequence Identity: 32% (9 aa)

NITSLTLDLWDNSIGDKGVKDLATGIAQ
| . ..|.|..| .||.|.. |. |...
NCSLRELWLSNNKLGDEGCRQLCEGLKH
LRR_RI 15779.AA LRR_RI 860-887 32 0.013609 11.71 SMART 1-28 (28) Show / Hide 
Range on Protein: 860-887
Range on HMM: 1-28/28
Sequence Identity: 32% (9 aa)

NITSLKLDLSFNSIGAQGAKDLATGIAQ
| . ..|.|| | .|. |.. |. |...
NCSLRELWLSNNKLGDEGCRQLCEGLKH
LRR_RI 15779.AA LRR_RI 890-917 35 0.002778 16.58 SMART 1-28 (28) Show / Hide 
Range on Protein: 890-917
Range on HMM: 1-28/28
Sequence Identity: 35% (10 aa)

NITNLMLDLQGNSIGDEGAKDLALGIEQ
| . . |.|..| .||||.. |. |...
NCSLRELWLSNNKLGDEGCRQLCEGLKH
LRR_RI 15779.AA LRR_RI 920-947 32 0.014669 11.48 SMART 1-28 (28) Show / Hide 
Range on Protein: 920-947
Range on HMM: 1-28/28
Sequence Identity: 32% (9 aa)

NITSLTLDLWRNSIGDQGSKDLATGIEQ
| . ..|.|. | .|| | . |. |...
NCSLRELWLSNNKLGDEGCRQLCEGLKH
LRR_RI 15779.AA LRR_RI 980-1007 35 0.024403 9.92 SMART 1-28 (28) Show / Hide 
Range on Protein: 980-1007
Range on HMM: 1-28/28
Sequence Identity: 35% (10 aa)

NITSLTLHLSRNSIGDQGAKYLDTGIEQ
| . ..|.|| | .|| |.. |  |...
NCSLRELWLSNNKLGDEGCRQLCEGLKH
LRR_RI 15779.AA LRR_RI 1010-1037 28 0.016934 11.04 SMART 1-28 (28) Show / Hide 
Range on Protein: 1010-1037
Range on HMM: 1-28/28
Sequence Identity: 28% (8 aa)

NITSLMLDLSDNSIDAQGAKDLAKGISQ
| . . |.||.| . . |.. |..|...
NCSLRELWLSNNKLGDEGCRQLCEGLKH
LRR_RI 15779.AA LRR_RI 1040-1067 35 0.002391 17.04 SMART 1-28 (28) Show / Hide 
Range on Protein: 1040-1067
Range on HMM: 1-28/28
Sequence Identity: 35% (10 aa)

NITNLMLDLQQNSIGDEGAKDLATGIAQ
| . . |.|..| .||||.. |. |...
NCSLRELWLSNNKLGDEGCRQLCEGLKH
LRR_RI 15779.AA LRR_RI 1070-1097 32 0.006281 14.08 SMART 1-28 (28) Show / Hide 
Range on Protein: 1070-1097
Range on HMM: 1-28/28
Sequence Identity: 32% (9 aa)

NITCLTLDLWRNSIGDQGSKYLATGIEQ
| . ..|.|. | .|| | . |. |...
NCSLRELWLSNNKLGDEGCRQLCEGLKH
LRR_RI 15779.AA LRR_RI 1202-1220 36 0.226532 3.09 SMART 10-28 (28) Show / Hide 
Range on Protein: 1202-1220
Range on HMM: 10-28/28
Sequence Identity: 36% (7 aa)

RGNSIGDEGAKDLATGIAQ
..| .||||.. |. |...
SNNKLGDEGCRQLCEGLKH
LRR_RI 15779.AA LRR_RI 1223-1250 32 0.002742 16.62 SMART 1-28 (28) Show / Hide 
Range on Protein: 1223-1250
Range on HMM: 1-28/28
Sequence Identity: 32% (9 aa)

NITNLTLDLSGNSIGAQGAKDLATGISQ
| . ..|.||.| .|. |.. |. |...
NCSLRELWLSNNKLGDEGCRQLCEGLKH
LRR_RI 15779.AA LRR_RI 1253-1280 32 0.019044 10.68 SMART 1-28 (28) Show / Hide 
Range on Protein: 1253-1280
Range on HMM: 1-28/28
Sequence Identity: 32% (9 aa)

NITSLTLHLQRNSIGDEGAKDLATTIVQ
| . ..|.|. | .||||.. |. .. .
NCSLRELWLSNNKLGDEGCRQLCEGLKH