Gene 29634 (Tetrahymena)

29634

Species: Tetrahymena
Alias: 1154, TTHERM_00963270, PreTt29634, 29634, n.29634, 179.m00048
External Links: Tetrahymena Genome Database (TGD)
Annotation: Secondary Group: Other, Secondary Family: Ciliate_C8_Cterm,

Classification

Group: Other
Family: Ciliate-C8
Subfamily: C8

Sequence

Name Sequence Type Origin Length Description Download
29634.AA Protein None 829 None Fasta, JSON
29634.kin_dom Protein Kinase Domain None 164 None Fasta, JSON
29634.kin_dom2 Protein Kinase Domain None 203 None Fasta, JSON
29634.NA RNA None 4947 None Fasta, JSON

Protein domain

Protein domains of 29634.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 29634.AA C8 171-385 61 2.2e-119 402.92 In-house 1-226 (226) Show / Hide 
Range on Protein: 171-385
Range on HMM: 1-226/226
Sequence Identity: 61% (138 aa)

FSNFEYLNNGTYALILRAQNTKENRIVALKFLTCSNKEDKNGIESLKKEYEMLQKFSQSDFLVNVYDCFYLMEEDVQQDKDGNEKIILTKEKSYFVLEME
|.||.||..| |...|.|.|.|.|| ..|||..|.||.|...|||..|||||.|.|.|.||.||.|||||.|.|.....|..||||..|.|||.|| |||
FNNFQYLSFGAYGMVLKAKNVKDNREIVLKFQKCQNKQDIQNIESIMKEYEMPQVFQQYDFYVNEYDCFYEMYEVFEEEKCSNEKIVQTEEKSCFVMEME

LCQQNLKELFDFFRNKQLP-SKEIKEIIAIQMLEGLNNLHVKNIMHRDIKPHNFLVQASQTYGFTIKICDLAFASSVTKSKSHYISKK----GTDAYFAP
||.||||.|.|..||||.. |||.||||||||..|.|..|.|||||||||||||||...|.|||.||.||..||| |.|.|||..|||    ||.|||||
LCEQNLKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAP

EVEIG------QSRIQSDLFSLGLVL
|.| .      |.||||||||.||||
EIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase 29634.AA Ciliate-C8 180-385 55 2.4e-117 396.16 In-house 1-238 (238) Show / Hide 
Range on Protein: 180-385
Range on HMM: 1-238/238
Sequence Identity: 55% (131 aa)

GTYALILRAQNTKENRIVALKFLTCSNKEDKNGIESLKKEYEMLQKFSQSDFLVNVYDCFYLMEEDVQQDKDGNEKIILTKEK---SYFVLEMELCQQN-
| ....|.|||.|.||.|||||..|.||..||..|...|||||...|.|..|.|.||||||||||....|.|||.||. |.||   |.||.|||.|||| 
GAFGMVLKAQNKKQNRKVALKFRECVNKIQKNQMEHEIKEYEMIMQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKKSFFVMEMEKCQQNC

-LKELFDFFRNKQLP-SKEIKEIIAIQMLEGLNNLHVKNIMHRDIKPHNFLVQASQTYGFTIKICD------LAFASSVTKSKSHYISKK--GTDAY---
 ||..||..|.||.. |...||||||||....|.||..||||||||||||||. .|.|..|||.||      ..||| ..|.||||.|||  |||.|   
NLKQYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEM

--------FAPEVEIGQSRIQSDLFS-------LGLVL
        |||||| .|||||||.||       .||||
YFCGNWGYFAPEVEKKQSRIQSDIFSKKSDSYSVGLVL
Kinase 29634.AA C2 180-398 36 4.1e-63 214.42 In-house 1-245 (245) Show / Hide 
Range on Protein: 180-398
Range on HMM: 1-245/245
Sequence Identity: 36% (91 aa)

GTYALILRAQNTKENRIVALKFLTCSNKEDKNGIESLKKEYEMLQKFSQSDFLVNVYDCFYLMEEDVQQDKDGNEKIILTKEK---------SYFVLEME
|  .|.| | | |.||.||||   | .  | || ... |||....... . ....||..||| ...   .   |. .. ..|.         . .|.|.|
GAFGLVLKAFNKKQNRHVALKIQEC-QSNDINGMHEVQKEYGIMRQCQNMPYIIKVYNYFYLTVNKKEDEDEDNDEEEKEQENIKKQKNEKKIFVVYEQE

LCQQNLKELFDFFRNKQ-LPSKEIKEIIAIQMLEGLNNLHVKNIMHRDIKPHNFLVQASQTYGFTIKICD----------LAFASSVTKSKS-HYISK-K
 || |||  |.  |...  |....|.|.||||. . | || ..| |||||| |||.| .|    |||.||          ..||| . ..||  ..|| |
FCQGNLKQYFNRCRKQNSYPCQQMKMIMAIQMMDSINYLHRFDIVHRDIKPSNFLYQFDQQGIPTIKLCDYHIQYQKKCDFDFASKLKYNKSRIHFSKFK

GTDAY----FAPEVEIGQSRIQSDLFS-LGLVLLELDNLKVLNENW
.| .|    |||||. .  . .||||| .|.||||||| .  . . 
WTQQYYQHIFAPEVYQNIYKKNSDLFSTVGYVLLELDNMQQYTICC
Kinase 29634.AA Pkinase 171-388 22 2.1e-24 87.38 Pfam 1-205 (293) Show / Hide 
Range on Protein: 171-388
Range on HMM: 1-205/293
Sequence Identity: 22% (52 aa)

FSNFEYLNNGTYALILRAQNTKENRIVALKFLTCSNKEDKNGIESLK-KEYEMLQKFSQSDFLVNVYDCFYLMEEDVQQDKDGNEKIILTKEKSYFVLEM
.   . .  |...   .... ....|||.| .  ......  .. ..  | ...... .... |  ||.|.                     |..  . |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--------------------KDHIYMVM

ELCQQNLKELFDFF------RNKQL--PSKEIKEIIAIQMLEGLNNLHVKNIMHRDIKPHNFLVQASQTYGFTIKICDLAFASSV-TKSKSHYISKKGTD
|.|.  |. ..| |      |.. .  . .|.| ..  |.|.||. .| ..|.|||.|| |.|.    . . ..||||  .|  . . ..| . .  || 
EYCEGGLY-VMDLFDYISTWRHGCFYFSEWECKFYMY-QILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTP

AYFAPEVEIGQSRIQ--------SDLFSLGLVLLEL
 | ||||      |.        .| .|.|..| |.
WYMAPEV------IRGGQYYGPKVDMWSCGCILYEM
Kinase 29634.AA Ciliate-A1 269-388 27 8.6e-23 74.38 In-house 80-221 (301) Show / Hide 
Range on Protein: 269-388
Range on HMM: 80-221/301
Sequence Identity: 27% (41 aa)

MELCQQNLKELFDFFRNKQ-LPSKEIKEIIAIQMLEGLNNLHVKNIMHRDIKPHNFLVQ-ASQTYGFTIKICDLAFASSVTKSK----------------
|| || ..  ||... ..  .   || ||   |. ||.  .| .||.|||.|| | |.    .     .|||||        ..                
MEYCQYGN--LFNYCYQNDYMKKEEIYEIC-YQIIEGYADIHDHNILHRDLKPQNILIHFDDK-----WKICDLGMSKQLEQNQDCCDDVNGCSFSKQVN

--SHYISKKGTDAYFAPEV----------EIGQSRIQSDLFSLGLVLLEL
  .| ..| |.  | .||             .    |||..|||.....|
KHYHTCKKGGNLYYMSPEQYQMHYRDQMFIENKIYKQSDMYSLGCIICFL
Kinase 29634.AA CMGC 171-355 16 1.1e-22 70.58 In-house 1-287 (513) Show / Hide 
Range on Protein: 171-355
Range on HMM: 1-287/513
Sequence Identity: 16% (47 aa)

FSNFEYLNNGTYALILRAQN--------------TKENRIVALKFLTCS-NKED------KNGIE-SLKKEYEMLQKFS---------------QSDF-L
. . ...  |||.   ....              .. |.|||.| .    ..|.      |.|.  .   | ..|....               . .  .
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

VNVYDCFYLMEEDVQQDKDGNEKIILTKEKSYFVLEMELCQQNLKELFDFFR-------NKQLPSKE------------IKEII-----AIQMLEGLN--
|. ||.||  ..| ....| .. |    .  .. | .|.....|... .  .       .. |.  .            || ..     . |.|.||.  
VKLYDIFYHKNSDGNEYEDKHI-I-SQ-HFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLK

NLHVKN--IMHRDIKPHNFLVQASQTY----------------GFTIKICDLAFASSVTKS------------------------KSHYIS
 .| ..  |.|||.|| | |.    ..                 ...||||  .| .. .                          .||..
YCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVV
Kinase 29634.AA CAMK 176-367 14 7.5e-21 63.27 In-house 1-291 (425) Show / Hide 
Range on Protein: 176-367
Range on HMM: 1-291/425
Sequence Identity: 14% (45 aa)

YLNNGTYALILRAQNTKEN------------RIVALKFLTCSNKEDKN-------------------------GIESLKKEYEMLQKFS------QSDFL
 |  |...   ...... .            . || |..  .   ||.                           .....|.|...| .      .   .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VNVYDCFYL-----------MEEDVQQDKDGNEKIILT-KEKSYFVL-EMELCQQN--LKELFDFFRNK----------------QLPSKEIKEIIAIQM
.. |. .               ...         .. | ... |.|.  ||.|.    . .|||. . .                 .. .| . ..  |.
IKLYEVYEDPHYFKNTNDYET-SKQ---------VF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFR-QI

LEGLNNLHVKNIMHRDIKPHNFLVQASQTYG-------------FTIKICDLAFASSVTKSKSHYIS-----------------------KKGTDAYFA-
..... .| .||.|||.|| | |.. . .               ..|||.|  ||  ...... .                           || .| | 
CSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAA

PEV
|||
PEV
Kinase 29634.AA Ciliate-E2 259-388 24 5.5e-20 65.29 In-house 103-289 (365) Show / Hide 
Range on Protein: 259-388
Range on HMM: 103-289/365
Sequence Identity: 24% (49 aa)

TKEKSYFVLEMELCQQNLKELFDFFRNKQLPSKEI---------KEI--IAIQMLE---------------GLNNLHVKN-IMHRDIKPHNFLVQASQTY
.| .... | ||.||.  ..|||. .|... ....         |||  |  | |.               .|. || || |.|||||| | |.      
EKDDNNIYLVMEYCQG--GDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

GFTIKICDLAFASSVTKS---------KSHYISKK-----------------------GTDAYFAPEVEIGQSR----------IQSDLFSLGLVLLEL
   |||.|. ..  ....            |.  |                       ||  | |||.  |..            ..|..||| .| |.
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM
Kinase 29634.AA STE 171-388 19 1.4e-19 65.88 In-house 1-261 (359) Show / Hide 
Range on Protein: 171-388
Range on HMM: 1-261/359
Sequence Identity: 19% (54 aa)

FSNFEYLNNGTYALILRAQNTK---------------ENRIVALKFLTCSNKE----------DKNG----IESLKKEYEMLQKFSQ-SDFLVNVYDCFY
. . | . .|..    .| | |                ..|.| | .  .|..          ..|     .....|| ....|... ... |. |.|..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

LMEEDVQQDKDGNEKIILTKEKSYFVLEMELCQ-QNLKELFD--FFRNKQLPSK---------EIKEIIAIQMLEG-LNNLHVKNIMHRDIKPHNFLVQA
   ..             .|....  . ||..    | .. .  . ..|.|...         ..  .|. | |.| |. || ..|.|||||| | |.  
KEGHN-------------HKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--

SQTYGFTIKICDLAFASSVTKS----------------KSHYISKKGTDAYFAPEVEIG-QSR------IQSDLFSLGLVLLEL
       .|.||  .....|.|                ...  .  ||  . ||||  . ..       ...|  |||....|.
-------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEM
Kinase 29634.AA TKL 297-388 21 6e-18 61.21 In-house 137-282 (364) Show / Hide 
Range on Protein: 297-388
Range on HMM: 137-282/364
Sequence Identity: 21% (31 aa)

IAIQMLEGLNNLHV--------KNIMHRDIKPHNFLVQASQT----------YGFTIKICDLAFASSVTKSKS-------------------HYISKKGT
.|...  |.| ||         ..| |||.|..| ||    |          .  ..||||. .. ....|..                   . ... ||
WALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGT

DAYFAPEV---EI--------------GQSRIQSDLFSLGLVLLEL
 .. ||||   ..              ..   ..| .| |.|| |.
PRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEI
Kinase 29634.AA S_TKc 171-451 19 1.3e-16 62.38 SMART 1-231 (231) Show / Hide 
Range on Protein: 171-451
Range on HMM: 1-231/231
Sequence Identity: 19% (58 aa)

FSNFEYLNNGTYALILRAQNTKENRIVALKFLTCSNKEDKNGIESLKKEYEMLQKFSQSDFLVNVYDCFYLMEEDVQQDKDGNEKIILTKEKSYFVLEME
.   . .  |...   .....| .||||.| .           |....| ..|.|  . ...|. ||.|.                      ... . ||
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD---------------------DHLYMVME

LCQQNLKELFDFFRNKQ-------LPSKEIKEIIAIQMLEGLNNLHVKNIMHRDIKPHNFLVQASQTYGFTIKICDLAFASSVTKSKSHYISKKGTDAYF
.| ..| .|||. ....       .|  ... ... |....|. .| ..|.|||.|| | |.        .|||||  .|  .        .  ||  | 
YCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMY-QICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL-------TTFCGTPWYM

APEVEIGQSRIQSDLFSLGLVLLELDNLKVLNENWIDFNIKAEIHQGKAIASKYQIDRNSNIYKIAKICLKLNYLERNTSGDLLS--------ELI
||||  | ..  .|  |.| .| |.   . . .     .... ... .           .    . . ||. .  .| |  ..|         . .
APEVL-GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 29634.AA Ciliate-E1 265-379 23 3.3e-16 49.6 In-house 72-202 (202) Show / Hide 
Range on Protein: 265-379
Range on HMM: 72-202/202
Sequence Identity: 23% (31 aa)

FVLEMELCQQNLKELFD---------FFRNKQLPSKEI-KEIIAIQMLEGLNNLHVKNIMHRDIKPHNFLVQASQTYGFT-IKICD-LAFASSVTKSKSH
... .|.|...||. ..          ....|   ..  |. |..|...||. || .||.||||||.| |.  .  | .. . |.. |   .  .. ...
CIIIFECCCCSLKDYLQNHNRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKG

YISKKG-TDAYFAPEV-EIGQ--SRIQSDLF
|...   .  |. ||. .. .    ..||..
YTHYYYPPEQYNCPEQEHNKNQKINYKSDIY
Kinase 29634.AA Ciliate-E2 171-245 12 6e-06 16.34 In-house 1-107 (365) Show / Hide 
Range on Protein: 171-245
Range on HMM: 1-107/365
Sequence Identity: 12% (13 aa)

FSNFEYLNNGTYALILRAQNTKENRIVALK-----------------FLTCSNKEDKNGIESLKKEYEMLQ---------------KFSQSDFLVNVYDC
.   . . .|... . .... |... .|.|                 ..   .   ||.||..|.|  ...               .. ....... |.|
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FYLMEED
|. . ..
FQEKDDN
Kinase 29634.AA Ciliate-E1 177-264 15 5.1e-05 12.81 In-house 1-106 (202) Show / Hide 
Range on Protein: 177-264
Range on HMM: 1-106/202
Sequence Identity: 15% (17 aa)

LNNGTYALILRAQNTKEN-RIVALKFLTCSNKEDKNGIESLKKEYE-MLQKFSQSDFLVNVYDCFY---------LMEEDVQQDKDGNE--------KII
. || ......| . . | . ||.|.  |  ....| .....|||  ... | . . .....|...         ..|.  ...|| ..        ...
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC

LTKEKSY
 ......
QQNQNQF
Kinase 29634.AA Ciliate-A1 171-208 17 0.013683 4.56 In-house 1-39 (301) Show / Hide 
Range on Protein: 171-208
Range on HMM: 1-39/301
Sequence Identity: 17% (7 aa)

FSNFEYLNNGTYALILRAQNTKENR-IVALKFLTCSNKE
.     .  | .  ..|| .   ..  ...| . |.|.|
YHVVQLIDKGSFGVVMRAYDIQNQKKYLCCKIIICTNFE
Kinase 29634.AA C8 516-717 49 4.1e-102 345.53 In-house 1-226 (226) Show / Hide 
Range on Protein: 516-717
Range on HMM: 1-226/226
Sequence Identity: 49% (112 aa)

VNNFQILSFGSYGMVLSTKKVNLKNKEIVLKIQKIANEQQIQNEIRIMQQLKTPLVVQLYDNYVIEKVTSPEKYVVFELEKCS-----------CSLQD-
.||||.||||.|||||..|.|. .|.|||||.||. |.|.|||...||.....|.|.|.||.||.|... .|.|.|||.||||           |.... 
FNNFQYLSFGAYGMVLKAKNVK-DNREIVLKFQKCQNKQDIQNIESIMKEYEMPQVFQQYDFYVNEYDCFYEMYEVFEEEKCSNEKIVQTEEKSCFVMEM

----------YLERQAKEGEFSDEEKLNIALQIIDSVNYIHCFNIIHRDIKPDNFLVSLDGNKL-QIKLCDFGLSAQLGKNCEQINILDM--VGNWIYMA
          |.||. |...||.|.|..||.|.||.||||||.||.||||||.|||| ||.|.. .|||||||...|..||...| . .|  .|.| |.|
ELCEQNLKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFA

PEILTKNDNENKIYSKKSDSYAVGLLL
|||..|.||..|.|...||.. |||.|
PEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase 29634.AA Ciliate-C8 525-717 40 9.9e-99 334.31 In-house 1-238 (238) Show / Hide 
Range on Protein: 525-717
Range on HMM: 1-238/238
Sequence Identity: 40% (96 aa)

GSYGMVLST------KKVNLKNKEIVLKIQKIANEQQIQNEIRIMQQLKTPLVVQLYDNYVIEKVTSPEK-----------------YVVFELEKCS--C
|..||||..      .||.||..|.|.||||. .|..|.....|||....|.|||.||..........|.                 ..|.|.|||.  |
GAFGMVLKAQNKKQNRKVALKFRECVNKIQKNQMEHEIKEYEMIMQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKKSFFVMEMEKCQQNC

SLQDYLER-QAKEGEFSDEEKLNIALQIIDSVNYIHCFNIIHRDIKPDNFLVSLD-GNKLQIKLCD------FGLSAQLGKNCE---------QINILDM
.|..|..| . |....|...|..|| |.||||||.|||||.||||||.||||..| .. ..|||||      ||...|| ||..         .. ...|
NLKQYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEM

--VGNWIYMAPEILTK-NDNENKIYSKKSDSYAVGLLL
  .||| |.|||...| ......|.||||||| |||.|
YFCGNWGYFAPEVEKKQSRIQSDIFSKKSDSYSVGLVL
Kinase 29634.AA C2 525-717 27 2.7e-46 156.17 In-house 1-232 (245) Show / Hide 
Range on Protein: 525-717
Range on HMM: 1-232/245
Sequence Identity: 27% (65 aa)

GSYGMVLSTKKVNLK-NKEIVLKIQKIAN-----EQQIQNEIRIMQQLK-TPLVVQLYD-NYVIEKVTSP------------EK----------YVVFEL
|. |.||  |  | | |....||||..       ....|.|..||.|..  |.....|.  |. ..  .             |.           ||.|.
GAFGLVL--KAFNKKQNRHVALKIQECQSNDINGMHEVQKEYGIMRQCQNMPYIIKVYNYFYLTVNKKEDEDEDNDEEEKEQENIKKQKNEKKIFVVYEQ

EKCSCSLQDYLERQAKEG-EFSDEEKLNIALQIIDSVNYIHCFNIIHRDIKPDNFLVSLDGNKL-QIKLCD--------FGLSAQLGKNCEQINILDMVG
|.|.. |. |..|. |.  ......|  .| |..||.||.|.|.|.||||||.|||...| . .  |||||          ..      .....| .  .
EFCQGNLKQYFNRCRKQNSYPCQQMKMIMAIQMMDSINYLHRFDIVHRDIKPSNFLYQFDQQGIPTIKLCDYHIQYQKKCDFDFASKLKYNKSRIHFSKF

NWIYMAPEILTKNDNENKIYSKKSDSYA-VGLLL
.|..   . ...  .. .|| |.|| .  ||. |
KWTQQYYQHIFAPEVYQNIYKKNSDLFSTVGYVL
Kinase 29634.AA CAMK 521-717 19 7.3e-34 105.96 In-house 1-324 (425) Show / Hide 
Range on Protein: 521-717
Range on HMM: 1-324/425
Sequence Identity: 19% (63 aa)

ILSFGSYGMVLSTKKVNLKN-----------KEIVLKI---QKIA----------------------------NEQQIQNEIRIMQQ-------LKTPLV
.|  ||.| |   .  | ..           ..   ||   .|.                             .......||.||..       |. | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLYDNYVIEKV--------TSP------EKYVVFEL---EKCSC-----SLQDYLERQAK------------EGEFSDEEKLNIALQIIDSVNYIHCFN
..||. |  ...        |        .|.... .   | ||       | ||. .. .            .| |. .|   .  ||.. |.|.|  |
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDIKPDNFLVSLDG--------------NKLQIKLCDFGLSAQLGKNCEQI---------------------NILDMVGNWIYMA-PEILTKN----
|.|||.||.| |.. ..              |. .||..|||..... .. ..                         ...|   ||| ||.| ..    
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----DNENKIYSKKSDSYAVGLLL
     |.|.. |..|.|  ..| .|
MQNATDEEKPYYGPKCDMWSCGVIL
Kinase 29634.AA S_TKc 516-787 22 1.5e-30 108.73 SMART 1-231 (231) Show / Hide 
Range on Protein: 516-787
Range on HMM: 1-231/231
Sequence Identity: 22% (63 aa)

VNNFQILSFGSYGMVLSTKKVNLKNKEIVLKIQKIANEQQIQNEIRIMQQLKTPLVVQLYDNYVIEKVTSPEKYVVFELEKCSC---SLQDYLERQAKEG
    ...  |..| |   ....  ...  .|| |    ..|..||.|... . | .|.||| ..        ... . .| |.    .| ||.... ..|
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGRHG

E---FSDEEKLNIALQIIDSVNYIHCFNIIHRDIKPDNFLVSLDGNKLQIKLCDFGLSAQLGKNCEQINILDMVGNWIYMAPEILTKNDNENKIYSK-KS
    |.  .   .. ||.. ..|.|  .|||||.||.| |..      .||.|||||..||           ..|   |||||.|         |.| |.
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL---------TTFCGTPWYMAPEVL--------GYGKCKC

DSYAVG-LLLSLVDNYLILKENLAITFINMAQKKYDEPFKNINIKRDTEIFKFIKLLVVWKRVNRASLSIIVE----SNSKKFK
| ...| .|  ..  |     ... .| ..                . |   ||. . ..   .| .   . .     ..  . 
DWWSCGCILYEMLCGYPPFP-QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 29634.AA Ciliate-E1 522-711 25 1.1e-29 93.98 In-house 1-202 (202) Show / Hide 
Range on Protein: 522-711
Range on HMM: 1-202/202
Sequence Identity: 25% (54 aa)

LSFGSYGMVLSTKKVNLKNKEIVLKIQKIA---NEQQIQNEIRIMQQLKTPLVVQLYDNYVIEKVTSPEKYVV-FELEKCSCSLQDYLE----------R
.. ||...|.  |. | ..... .||...    |....|.||.  ....  .  . |  ..|.   . . |.  . .|.|.|||.|||.           
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC

QAKEGEFSDEEKLNIALQIIDSVNYIHCFNIIHRDIKPDNFLVSLDGNKLQIKLCDFGLSA--QLGKNCEQ---INILDMVGNWIYMAPEILTKNDNENK
| ....|....|..|. |.|| ....| .|||||||||.| |.. . .....   |||.|   .. .| ..     .  .  .. |. |  .  . |.|.
QQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQ-GNYVYC--DFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCP--EQ-EHNKNQ

IYSKKSDSY
....||| |
KINYKSDIY
Kinase 29634.AA Pkinase 544-717 28 3.5e-27 97.18 Pfam 31-202 (293) Show / Hide 
Range on Protein: 544-717
Range on HMM: 31-202/293
Sequence Identity: 28% (54 aa)

VLKIQKIANEQQIQN----EIRIMQQLKTPLVVQLYDNYVIEKVTSPEKYVVFELEKCSC-----SLQDYLERQAKEGEF--SDEEKLNIALQIIDSVNY
..| ...  ......    ||.||. |. | .|.||| .        .... . .| | .     .| ||...  ..| |  |..|  ....||.  ..|
IIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDLFDYIST-WRHGCFYFSEWECKFYMYQILRGLEY

IHCFNIIHRDIKPDNFLVSLDGNKLQI----KLCDFGLSAQLGKNCEQINILDMVGNWIYMAPEILTKNDNENKIYSKKSDSYAVGLLL
.|  .|||||.||.|.|  .| |. .|    |.|||||..|.  .  .    . .|   |||||..     ... |..|.| ...|..|
CHSMGIIHRDLKPENIL--ID-NNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIR----GGQYYGPKVDMWSCGCIL
Kinase 29634.AA CMGC 516-667 16 3.8e-27 85.5 In-house 1-251 (513) Show / Hide 
Range on Protein: 516-667
Range on HMM: 1-251/513
Sequence Identity: 16% (41 aa)

VNNFQILSFGSYGMVLSTKKVNLK-------------NKEIVLKIQKIANEQQIQ---------------NEIRIMQQLK-----------------TPL
  . . .  |.||.| . .  . .             |... .|. | .   ..|                ||.|...|.                  . 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VVQLYDNYVIEKVTSPEK-----------YVVFELEKCSCSLQDYLERQA--KEG----EFSDEE------------KLNIA------LQIIDSVN--YI
.|.||| .. .. ...|.           .. .  | . ..| .|....   . |    ..|. .            . ..        ||. ...  |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HCFN--IIHRDIKPDNFLVSLDGNK-----------------LQIKLCDFGLS
|  .  |||||.|| | |.. ..                    ..|.|||||.
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLA
Kinase 29634.AA Ciliate-E2 516-717 22 4.8e-26 86.39 In-house 1-286 (365) Show / Hide 
Range on Protein: 516-717
Range on HMM: 1-286/365
Sequence Identity: 22% (66 aa)

VNNFQILSFGSYG-----MVLSTKKVN-----------------LKNKEIVLKIQK------IANEQQIQNEIR----------IMQQLKTPLVVQLYDN
 .  ... .|..|      | ...|                    |.|.. .||.|      | .|..| .||.          |..||. | ....|. 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YVIEKVTSPEKYVVFELEKCSC-SLQDYLERQAKE--------GEFSDEEKLNIALQIID---------------SVNYIHCFN-IIHRDIKPDNFLVSL
.  ..    .... . .| |.  .|.||.. . |         . |...| ..|  ||..                ..|.|  | ||||||||.| |.  
FQEKD----DNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--

DGNKLQIKLCDFGLSAQLGKN---------CEQINILD---------------------MVGNWIYMAPEILTKNDNEN----KIYSKKSDSYAVGLLL
      ||..||||| .. ..         |. .                          .|.  ||||||| . ...|    | |..|.| ...| .|
------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL
Kinase 29634.AA TKL 619-717 25 5.3e-25 86.98 In-house 134-279 (364) Show / Hide 
Range on Protein: 619-717
Range on HMM: 134-279/364
Sequence Identity: 25% (37 aa)

KLNIALQIIDSVNYIHCFN--------IIHRDIKPDNFLVSLDGN-----------KLQIKLCDFGLSAQLGKNCEQINILDM-----------------
....||.|   .|| |  |        |||||.|..| ||  ...              .|.||||||  . .. ..  .  .                 
RCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQ

VGNWIYMAPEILTKNDNENK-----------IYSKKSDSYAVGLLL
.|.  .||||.| ...| ..            ||.|.| |. |..|
CGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVL
Kinase 29634.AA STE 517-717 22 6.7e-25 84.93 In-house 1-258 (359) Show / Hide 
Range on Protein: 517-717
Range on HMM: 1-258/359
Sequence Identity: 22% (60 aa)

NNF-QILSFGSYG-MVLSTKK----VNLKNKEI-------------VLKIQKI-----------------ANEQQIQNEIRIMQQLK--TPLVVQLYDNY
  . ...  |..|  ..  ..     . |..|.             ......                   ..|||..||.||....   | .|. |. |
WEGIEKIGKGAFGTVYKAMNHKNCNIH-KTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

VIEK--VTS-PEKYVVFELEKCSC-SLQDYLE------------RQAKEGEFSDEEKLNIALQIIDS-VNYIHCFNIIHRDIKPDNFLVSLDGNKLQIKL
. |     .  | ... |.  ..  || | ..            ||. .. |. ..   |. ||.    .|.|  .||||||||.| |.        .||
FKEGHNHKNDDELWICMEY--MDGGSLDDIIKHKYGCGKPLNHNRQH-QHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL--------VKL

CDFGLSAQLGKNCE--------------QINILDMVGNWIYMAPEILTKNDNE-NKIYSKKSDSYAVGLLL
||||...|| ...               | .   .||   .||||....|..  .| |. |.| . .|...
CDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTI
Kinase 29634.AA Ciliate-A1 516-717 26 7.6e-15 46.91 In-house 1-218 (301) Show / Hide 
Range on Protein: 516-717
Range on HMM: 1-218/301
Sequence Identity: 26% (60 aa)

VNNFQILSFGSYGMVLSTKKVNLKNKE--IVLKIQKIANEQQIQ---NEIRIMQQLKTPLVVQLYDNYVIEKVTSPEKYVVFELEKCSCSLQDYLERQAK
    | .  ||.| |.  .  .. |.   . .|| .. |  | .   .| |...|.  . |.  |.   ..  |       .  |.|   ..  .  | .
YHVVQLIDKGSFGVVM--RAYDIQNQKKYLCCKIIICTNFEQYKNNIQEYRKCKQINHNNVIKNYQQ--LYYNTNNKECMFIIMEYCQYGNLFNYCYQND

EGEFSDEEKLNIALQIIDSVNYIHCFNIIHRDIKPDNFLVSLDGNKLQIKLCDFGLSAQL-GKN--CEQI-------------NILDMVGNWIYMAPEI-
    . ||   | .|||  .  ||  ||.|||.||.| |.   ... ..|.||.|.| || ...  |. .             .     ||  ||.||  
--YMKKEEIYEICYQIIEGYADIHDHNILHRDLKPQNILI---HFDDKWKICDLGMSKQLEQNQDCCDDVNGCSFSKQVNKHYHTCKKGGNLYYMSPEQY

---L-TKNDNENKIYSKKSDSYAVGLLL
   .  .   ||||| |.|| | .|. .
QMHYRDQMFIENKIY-KQSDMYSLGCII
Kinase 29634.AA TyrKc 516-786 20 9.8e-11 -49.08 SMART 1-280 (280) Show / Hide 
Range on Protein: 516-786
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

VNNFQILSFGSYGMVLSTKKVNLKNKEIVL--KIQKIANEQQIQNEIRIMQQL--KTPLVVQLYDNYVIEKV-----TSPEKYVVFELEKCSCSLQDYLE
.   ..|  | .| |   .       . |   .... | .. . .|.||| .|  . | .|.||   |. .       ..  ..|.|. .   .|.||| 
ITLGKKLGEGAFGEVYKGTWK-----IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLY--GVCTQQGRNFMYIEPLMIVMEYMPH-GDLKDYLR

RQAKEGEFSDEEKLNIALQIIDSVNYIHCFNIIHRDIKPDNFLVSLDGNKLQIKLCDFGLSAQLGKN---CEQINILDM----VGN--WIY--MAPEILT
.  ..  .. ...|....|| .  .|.|  |.||||.   | ||. ..   ..| .|||||  ..      |     ..     |.  . .  |||| . 
KHRPK--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH---TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-

KNDNENKIYSKKSD--SYAVGL--LLSLVDNYLIL-----KENLAITFINMAQKKYDEPFKN-----INIKRDTEIFKFIKLLVVWKRVNRASLSIIVES
      .... |||  |. | .  .... .          ..|  .   .  | .. .. .|           .|... .|     .  .| . | |   
----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIE-YVKQGYRMPQPPNDYPMSF-VCCPDEMYQIMKQCWHEDPEDRPTFSEI---

NSKKF
  ..|
-HECF
Kinase 29634.AA Pkinase_Tyr 554-667 30 0.000548 14.13 Pfam 48-158 (270) Show / Hide 
Range on Protein: 554-667
Range on HMM: 48-158/270
Sequence Identity: 30% (36 aa)

QQIQNEIRIMQQL-KTPLVVQLYDNYVIEKVTSP-EKYVVFELEKCSCSLQDYLERQ-AKEGEFSDEEKLNIALQIIDSVNYIHCFNIIHRDIKPDNFLV
.   .|..|| || . | .|.||   |. .   | . |.|.|. ..  .| ||| ..   .. .. ...|....|| .  .| .  |.||||.   | ||
EDFMREAKIMKQLGHHPNIVRLY--GVCTDQGEPNQIYIVMEYMPHG-DLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLV

SLDGNKLQIKLCDFGLS
.    ....| |||||.
TE---NNVVKICDFGLA