Gene 20853 (Tetrahymena)

20853

Species: Tetrahymena
Alias: 3700.m00246, 521, 20853, PreTt20853, 12.m00527, TTHERM_00151950
External Links: Tetrahymena Genome Database (TGD)
Annotation: Secondary Group: Other, Secondary Family: Ciliate-B1,

Classification

Group: Other
Family: Ciliate-B1

Sequence

Name Sequence Type Origin Length Description Download
20853.AA Protein None 825 None Fasta, JSON
20853.NA RNA None 2478 None Fasta, JSON
20853.kin_dom Protein Kinase Domain None 277 None Fasta, JSON
20853.kin_dom2 Protein Kinase Domain None 232 None Fasta, JSON

Protein domain

Protein domains of 20853.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 20853.AA Ciliate-B1 14-279 46 7.6e-162 543.97 In-house 1-290 (290) Show / Hide 
Range on Protein: 14-279
Range on HMM: 1-290/290
Sequence Identity: 46% (134 aa)

HVSNRKLGSGAISEVYYG-----ENYKQEKVAIKIVKREQYAEKKQNLYYQSELEVSKYLASKVNI---------YENICRIFDVIECQDQFFVIMEFCE
...|...|.||||.|.||     ....||....||.|..|...|.||.|||.|||....|..|.|.         ...||.|.|||.||.|...|||.||
YQQNNVIGQGAISQVFYGQFCQNQQCQQEVAVKKITKQTQDNDKQQNKYYQQELEIIQCLIKKMNNNKISCQSSPCDHICNIYDVIQCQQQYYIIMEYCE

GGNLLDYIMMQSQEDINKNILDIALEIVKGVSYLHQNGIVHRDLKPENIYLYKKRVPIYYNQFQDIYIFKIGDFGLSKFLKS-SNNSVVGTINYMAPEIL
.|.|..||....|.......||....|.||..|||...|.|||||||||...||.||||||..|..|||||.|||.||. .. ...|.||||||||||||
QGDLYNYIYNCHQNFTHDIVLDFCIQIAKGIQYLHKHKICHRDLKPENILIHKKNVPIYYNKQQNHYIFKITDFGISKMQQEYMMQSCVGTINYMAPEIL

E-NN-YGKEVDIWSIGCILYELKTQKQLFYSLKMDLREIISQIRAFNCQ--RSNDSNNIDYLIQV-----CLERNNLNRITIDKLQTKIE
. |. |.|.|||||.|||.||..|..|||.||.....|...|||.|.|.  .....|||...||.     ||.... ||||||.......
NFNQQYDKKVDIWSFGCIMYEIITNEQLFCSLGNTQQEVANQIRNFQCCDYQCHFQNNIYQEIQQLIQKYCLQPDPENRITIDQIIDRLM
Kinase 20853.AA S_TKc 14-282 28 3.3e-58 200.61 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-282
Range on HMM: 1-231/231
Sequence Identity: 28% (81 aa)

HVSNRKLGSGAISEVYYGENYK-QEKVAIKIVKREQYAEKKQNLYYQSELEVSKYLASKVNIYENICRIFDVIECQDQFFVIMEFCEG--GNLLDYIMMQ
    ||.|.|| ..|| . . | ...|||||.|             ..|... |         .||....||..  | ....||.|.|  |.|.|||  .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKR

SQE-----DINKNILDIALEIVKGVSYLHQNGIVHRDLKPENIYLYKKRVPIYYNQFQDIYIFKIGDFGLSKFLKSSNNSVVGTINYMAPEILENNYGK-
  .          .  .. .|.... |.|..||.||||||||| | .                ||.||||...|    ....|| .|||||.|   ||| 
GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--------------HIKICDFGLARQL----TTFCGTPWYMAPEVL--GYGKC

EVDIWSIGCILYELKTQKQLFYSLKMDLREIISQIRAFNCQRSNDSNNIDYLIQVCLERNNLNRITIDKLQT-----KIEKMK
..|.||.||||||. . . .|.    .. ... .|.         |     .|. ||...  .|.|. .. .     |.    
KCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 20853.AA Pkinase 14-278 28 7.7e-52 183.33 Pfam 1-293 (293) Show / Hide 
Range on Protein: 14-278
Range on HMM: 1-293/293
Sequence Identity: 28% (87 aa)

HVSNRKLGSGAISEVYYGENYKQEK-VAIKIVKREQYAEKKQNLYYQ-SELEVSKYLASKVNIYENICRIFDVIECQDQFFVIMEFCEGG----NLLDYI
 .  ||.|||. ..|| . . . .| ||.||.|..   ..|.      ||... | | .     .||.|..|. |  |   ..||.||||     | |||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-N----HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

M-MQSQED--INKNILDIALEIVKGVSYLHQNGIVHRDLKPENIYLY-KKRVPIYYNQFQDIYIFKIGDFGLSKFL---KSSNNSVVGTINYMAPEILE-
. ...       . . .....|..|. |.|..||.||||||||| .  .  ..          ..||.||||.|..   .| .....||..|||||..  
STWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA---------CVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRG

-NNYGKEVDIWSIGCILYELKTQKQLFYSL----KMDLREIISQIRA----FNCQRSND------------------SNNIDYLIQVCLERNNLNRITID
 . ||..||.||.||||||. . . .|..     ..| ...| .|.     |... ...                  | .   .|  ||...   |.|..
GQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAE

KLQTK--I
 .     .
QILQHPWF
Kinase 20853.AA Ciliate-E2 14-274 20 4.9e-50 169.95 In-house 1-359 (365) Show / Hide 
Range on Protein: 14-274
Range on HMM: 1-359/365
Sequence Identity: 20% (79 aa)

HVSNRKLGSGAISEVYYGENYKQEKVAIKIVKREQYAEKKQ--------NLYYQSELEVS--KYLASKVNIY---------------------ENICRIF
   ..|.|.|. . ||.....|. |  ...... |.  . |        ..|.   .. .  ... .. .|.                      ||....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQ-QRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMY

DVIE--CQDQFFVIMEFCEGGNLLDYIM---MQSQEDIN-------KNILDIALEIVK---------------GVSYLHQNG-IVHRDLKPENIYLYKKR
.. .   .. .. .||.|.||.|.|||     .... |.       | |..|  .|..               .. |||... |.|||.||||| .    
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

VPIYYNQFQDIYIFKIGDFGLSKFLKSSN----------------------------------NSVVGTINYMAPEILENN----------YGKEVDIWS
              || ||||||... .|                                  |...|| .|||||||..           |....||||
-------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWS

IGCILYELKTQKQLFYSLKMDLREIISQIRAFNCQRSNDSNNID-------------------YLIQV----CLERNNLNRIT-IDKL
.|.||||. . |  |          . ||   ... ..  .. |                    ||.     .|...  .||| ....
LGVILYEMLFGKPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQI
Kinase 20853.AA ULK 14-274 25 1.5e-49 170.91 In-house 1-323 (329) Show / Hide 
Range on Protein: 14-274
Range on HMM: 1-323/329
Sequence Identity: 25% (85 aa)

HVSNRKLGSGAISEVYYGENYKQ-----EKVAIKIVKREQYAEKKQNLY-------YQSELEVSKYLASK-VNIY--ENICRIFDVIECQ--DQFFVIME
 . |..||.|.   || |.| |.     ||||.|.. ...  .|... .        ..| .. | | |.  ...  .||.. .|. |..  . .. |||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FCEGGNLLDYIMMQ--SQEDI-NKN------ILDIALEIVKGVSYLHQNGIVHRDLKPENIYLYKK-------RVPIYYNQFQDIYIFKIGDFGLSKFLK
.|.||.| .||  .  . ||  .|.      .. .   |. |  .||...|.|||.||.|| . ..       .     .  . ....||.|||..|.. 
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKK-----V-HP-NGVLKIADFGFAKHVD

SS------NNSVV------GTINYMAPEILENN-----YG-KEVDIWSIGCILYELKTQK-----QLFYSLK-MDLREIISQ-------IRAFNCQRSND
..      . . |      ||  ||||.||...     |. ...||||.|||.||. . |     . |.... . ... | .       |. .. |  .|
NDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKD

------SNNIDYLIQVCLERNNLNRITIDKL
      |...  ||. .|...   ||... |
GNDPQISPECKDLIRRMLQYDEKDRISWEEL
Kinase 20853.AA ULK 14-218 27 1.6e-46 160.92 In-house 1-245 (324) Show / Hide 
Range on Protein: 14-218
Range on HMM: 1-245/324
Sequence Identity: 27% (70 aa)

HVSNRKLGSGAIS-EVYYGENYKQ----EKVAIKIVKREQYAEKKQN-------LYYQSELEVSKYLA---SKVNIYEN--ICRIFDVIECQ--DQFFVI
 . |..||.|.    || |.| |.    ..||.|.. . .  .||..          ..| .. | |    .     .|  |.. .|. |..  . .. |
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKH-----PNHHIVKLYDWFETSNHNNIYII

MEFCEGGNLLDYIMMQ--SQEDI-NKN------ILDIALEIVKGVSYLHQNGIVHRDLKPENIYLYK--------KRVPIYYNQFQDIYIFKIGDFGLSK
||.|.||.| .||  .  . |   .|.      .. .   |. |  .||...|.|||.||.|| . .        |      .  . ....||.|||..|
MEYCNGGDLEQYIKKNKKLPE-TEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKK------V-HP-NGVLKIADFGFAK

FLKS------SNNSVV------GTINYMAPEILENN-----YG-KEVDIWSIGCILYEL
.. .       . . |      ||  ||||.||...     |. ...||||.|||.||.
HVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEM
Kinase 20853.AA CAMK 19-216 20 4.9e-45 142.61 In-house 1-325 (425) Show / Hide 
Range on Protein: 19-216
Range on HMM: 1-325/425
Sequence Identity: 20% (67 aa)

KLGSGAISEVYYGENY-KQ------------EKVAIKIVKREQYAE------------------------KKQNLY-YQSELEVSKYLASK---VNIYEN
.||.|. ..|. ...   .            .||||||.....  .                        . ...   ..|.|. | | ..   ..  .|
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDH-PN

ICRIFDVIEC-------------------QDQFFVIM---EFCEGG----NLLDYIMMQSQ-------------EDI-NKNILDIALEIVKGVSYLHQNG
|.....|.|                    ..... .|   |.|.||     |.|||  ...               .  .    .   |. .| |.|...
IIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVHRDLKPENIYLYKKRVP--------IYYNQFQDIYIFKIGDFGLSKFLKSSNNS--------------------------VVGTINYMA-PEILENN-
||||||||||| | ..           |.    .. .  || |||.........|.                          ..||  ||| ||.|. . 
IVHRDLKPENILLDDNNDDSDPVEHDEIF-D--WNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKG

--------------YGKEVDIWSIGCILY
              ||...|.||.|.|||
HCNMQNATDEEKPYYGPKCDMWSCGVILY
Kinase 20853.AA TKL 20-278 19 1.9e-42 147.34 In-house 1-364 (364) Show / Hide 
Range on Protein: 20-278
Range on HMM: 1-364/364
Sequence Identity: 19% (71 aa)

LGSGAISEVYYGENYKQ----------EKVAIKIVKREQYAEKKQNL-----------------YYQSELEVSKYLA-SKVNI-YENICRIFD-VIECQD
.|||. .||| |. ...          . ||.|. |...  |.  |.                  .. . .  .. . .. ..  .||...   ......
IGSGGFGEVYKGK-WRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPC

------------QFFVIMEFCEGGNLLDYIMMQSQEDINKNILDIALEIVKGVSYLHQNG--------IVHRDLKPENIYLYKKRVPIYYN---QFQDIY
            |.. .||.|.||.||.|.           ....||.| .|..|||...        |.|||||..|| . ..  .   |     ....
GCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVS-NYMYNPNADW

IFKIGDFGLSKFLKSS----------------------NNSVVGTINYMAPEILENN-----------------YGKEVDIWSIGCILYELKTQKQLFY-
  ||.|||||.|.. |                      .....||...||||.|...                 | . .|..| | .|.|. | .. .| 
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYD

--SLKMDLR----EIISQIRAFN---------------CQRSNDSNNIDYLIQVCLERNNLNRITIDKLQTKI
  .  |...    |.....   .               |. ..    .  |.| | . .  .| . ...  ..
YPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase 20853.AA CAMK1 125-216 44 1.6e-40 115.49 In-house 116-207 (276) Show / Hide 
Range on Protein: 125-216
Range on HMM: 116-207/276
Sequence Identity: 44% (45 aa)

EIVKGVSYLHQNGIVHRDLKPENIYLYKKRVPIYYNQFQDIYIFK--IGDFGLSKFLKSSNN---SVVGTINYMAPEILEN----NYGKEVDIWSIGCIL
.|.. | |.|..|||||||||||.         ||..  |  | |  | ||||||.... .|    ..||. |.|||.||.     |.|..|.||||.|.
QILSAVEYMHSKGIVHRDLKPENL--------LYYDKDEDSKI-KRSIADFGLSKIFDHDENLMKTACGTPGYVAPEVLECKKDKPYDKACDMWSIGVIT

Y
|
Y
Kinase 20853.AA Ciliate-E2-Unclassified 14-274 22 5e-39 133.03 In-house 1-346 (352) Show / Hide 
Range on Protein: 14-274
Range on HMM: 1-346/352
Sequence Identity: 22% (80 aa)

HVSNRKLGSGAISEVYYGENYKQEKV-------AIKIVKREQYAEKKQNLYYQSELEVSKYLASKVN-IYE-----------NICRIFDVIECQDQ--FF
   ....|.|. ..||  .. || ..        |.|.|. |. .|. ..  . . . .|   . .. . .           ..... .. . ||.  ..
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKY-NKIMQQILLNHPHPFIVKMFYCFQDKQNIY

VIMEFCEGGNLLDYI----------------MMQSQEDINKNIL-----DIALEIVKGVSYLHQNG-IVHRDLKPENIYL-YKKRVPIYYNQFQDIYIFK
 .||.||||.|..||                |.|...   ....     ... .|..| .|||... |.|||.||||| .  ...           |  |
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK----------NYYIK

IGDFGLSKFLKSS------------------NNSVVGTINYM----APEILEN-NYG----KEVDIWSIGCILYELKTQKQLFYSLK-------------
| |||.||.....                   ....||.|||    |||.|.. ||.    ...|||| |.||||. ...  ||. .             
IIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWIN

-----MDLREII---SQIRAFN-----CQRSNDSNNIDY-LIQVCLERNNLNRITIDKL
     . ...|.    |.. |.     .. |.   ..   |.| .|. |  .|||....
NAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQI
Kinase 20853.AA CMGC 14-225 18 5.6e-38 121.73 In-house 1-343 (513) Show / Hide 
Range on Protein: 14-225
Range on HMM: 1-343/513
Sequence Identity: 18% (66 aa)

HVSNRKLGSGAISEVYYGENYK---------------QEKVAIKIVKREQYAEKKQ--------NLYYQSELEVSKYLA-----------SKVNIYEN-I
    .|.|.|. ..|| . . .               .|.||||..|...| | ..        .   . |..  |.|               |  .| |
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPFYEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNNI

CRIFDVIECQD-----------------QFFVIMEFCEGGNLLDYIMMQS---------------------------QEDINKNILDIALEIVKGVS--Y
 ...|..   .                 ... ..|...  .|..|| ...                           .  .. .|  ..  | .|.   |
VKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDH-DLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

LHQNG--IVHRDLKPENIYLYKK----------------RVPIYYNQFQDIYIFKIGDFGLSKFLKSS------------------------NNSVVGTI
.|...  |.||||||||| . ..                .        |. .. ||.||||.... .                         . . | | 
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPC--------QKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTR

NYMAPEILENN-----------YGKEVDIWSIGCILYELKTQ--------KQLF
 | ||||| .            |....|.||.|||..|. |         | ||
WYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLF
Kinase 20853.AA STE 15-222 23 1.5e-37 130.22 In-house 1-265 (359) Show / Hide 
Range on Protein: 15-222
Range on HMM: 1-265/359
Sequence Identity: 23% (66 aa)

VSN-RKLGSGAISEVYYGENYK----------------QEKVAIKIVKREQY--------------AEKKQNLYYQSELEVSKYLASKVNIYENICRIFD
  . .|.|.||  .||.. | |                .| .|||... |.                 ...   .. |... | . .   . .|| . ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNH---MHPNIVKYYG

VIECQ-------DQFFVIMEFCEGGNLLDYIM---MQSQEDI----------NKNILDIALEIVKG-VSYLHQNGIVHRDLKPENIYLYKKRVPIYYNQF
  .         |. ...||...|| | | |    .  ...            . |  |. .|.||  .|||...|.|||.|| || |            
CYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL------------

QDIYIFKIGDFGLSKFLKS-------------------SNNSVVGTINYMAPEILENN-------YGKEVDIWSIGCILYELKTQK
      |. |||... | .                    .|..|||  .||||....|       |.  .||||.|| . |. | |
-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase 20853.AA TyrKc 14-278 21 7.9e-17 49.43 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-278
Range on HMM: 1-280/280
Sequence Identity: 21% (67 aa)

HVSNRKLGSGAISEVYYGENYKQEKVAIKIVKREQYAEKKQNLYYQSELEVSKYLASKVNIY---ENICRIFDVIECQ-------DQFFVIMEFCEGGNL
 . ..|||.||  ||| |. .  ..||.| .| .            .|... . |      .   .|| |.. |.  |       .. ...||....|.|
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA------REDFMREARIMCKL------GGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL

LDYIMMQSQEDINKNILDIALEIVKGVSYLHQNGIVHRDLKPENIYLYKKRVPIYYNQFQDIYIFKIGDFGLSKFLKSS--------NNSV----VGT--
.||.     .  .|  |.... | .| .|||.....||||   |. . ...            . ||.|||||.....           ..     |   
KDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTM

--INYMAPEILENN-YGKEVDIWSIGCILYELKTQKQLFYSL----KMDLREIISQIRAF--NCQRSN--------DSNNIDYLIQVCLERNNLNRITID
  |  |||| .  . .  . |.|| |  ..|. |  |  |.     .|. .|.| ....     |  |         .  .  ... | ...  .| |  
LPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFS

KLQTKI
 .  ..
EIHECF
Kinase 20853.AA Pkinase_Tyr 90-143 35 1.5e-11 39.71 Pfam 81-137 (270) Show / Hide 
Range on Protein: 90-143
Range on HMM: 81-137/270
Sequence Identity: 35% (20 aa)

QFFVIMEFCEGGNLLDYIMMQ---SQEDINKNILDIALEIVKGVSYLHQNGIVHRDL
| ...||....|.||||   .    |    | .|.....| || .||......||||
QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDL
Kinase 20853.AA CAMK1 13-54 25 4.1e-05 10.74 In-house 1-46 (276) Show / Hide 
Range on Protein: 13-54
Range on HMM: 1-46/276
Sequence Identity: 25% (12 aa)

YHVSNRKLGSGAISEVYYGENYK----QEKVAIKIVK-REQYAEKKQ
| . . ..|.|| |||| ... .    ....|||. . ... ..|..
YEFGK-EIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDM
Kinase 20853.AA Pkinase_Tyr 169-218 29 0.000769 13.63 Pfam 151-207 (270) Show / Hide 
Range on Protein: 169-218
Range on HMM: 151-207/270
Sequence Identity: 29% (17 aa)

KIGDFGLSKFLKSSNNS-VVGT-----INYMAPE-ILENNYGKEVDIWSIGCILYEL
||.||||.. . .  .  ....     |  |||| | .. .  . |.|| |  ..|.
KICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEI
Kinase 20853.AA Pkinase_Tyr 17-56 27 0.215687 5.34 Pfam 4-50 (270) Show / Hide 
Range on Protein: 17-56
Range on HMM: 4-50/270
Sequence Identity: 27% (13 aa)

NRKLGSGAISEVYYGENY-----KQEKVAIKIVKREQYAEK---KQNL
..|||.||  ||| |. .     .. .||.|.. .|.. ..   .. .
GKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDF