Gene 15769 (Tetrahymena)

15769

Species: Tetrahymena
Alias: TTHERM_01001500, PreTt15769, 193, 190.m00079, 15769, 3820.m00300
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Atypical
Family: Alpha
Subfamily: VWL

Sequence

Name Sequence Type Origin Length Description Download
15769.AA Protein None 1029 None Fasta, JSON
15769.kin_dom Protein Kinase Domain None 206 None Fasta, JSON
15769.NA RNA None 3090 None Fasta, JSON

Protein domain

Protein domains of 15769.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
ZnF_C3H1 15769.AA ZnF_C3H1 8-34 29 8e-06 26.56 SMART 1-31 (31) Show / Hide 
Range on Protein: 8-34
Range on HMM: 1-31/31
Sequence Identity: 29% (9 aa)

NNK-LHCHFFHLTG---NCKKADKCPFLHGK
..|   | .|...|   .|.. |.|.|.|..
RYKTPPCKYFMRRGPPWYCPYGDRCKFAHPP
Zf-CCCH 15769.AA zf-CCCH 13-34 40 2.5e-05 21.73 Pfam 6-27 (27) Show / Hide 
Range on Protein: 13-34
Range on HMM: 6-27/27
Sequence Identity: 40% (9 aa)

CHFFHLTGNCKKADKCPFLHGK
|..|. || |.  |.|.| |..
CRYFMRTGYCPYGDRCKFAHPQ
VWA 15769.AA VWA 174-355 14 0.000775 10.22 SMART 1-193 (193) Show / Hide 
Range on Protein: 174-355
Range on HMM: 1-193/193
Sequence Identity: 14% (32 aa)

ELDLMFIMDCTGSM-SSWIQAVKDEILCIIATIKDVNKGYRDYGVSQRYSIFNFSDDMDEFEKF----LINVNAIAN-----------SDTPEDVAGGFK
.||..|..|..|||  ...|.||. |  .. ..            . |..|  ||||  .   .    .  | .. .           .  . . . . .
WLDIVFVIDGSGSMGPNNFQQVKQFI-KFVEQLD-----------GDRVGIVQFSDDVRVEFPLNYQDKDDVLKAIDNLQYKGKHDYFMGGGTNTG-ALQ

HANLQ------QWKSQA----------KYAVFIADCPAHGKEYNNDYSDRYPDGDPDGIDLKQEFKNLIKKGVKLYAIQITN-QTKQMFELFKQYNKEV-
.|  .        . .|          |  ....|  ..                 |  |... ...| ..|||...| . |  . .. ..  .   |  
YAMQNLFHERQG-RRGAGRPTKFWNVPKVIIVFTDGYSNDG-------------PHDPEDIRKAARELRRSGVKIFVIGVGNDDM-ELRQIASCP-GEHH

------CGQDLEILDLGYSTQG
        .. .|...  . . 
FFDVYDYDDLPDIFQHIIDWLC
Kinase 15769.AA VWL 477-679 67 2.2e-187 563.42 In-house 1-206 (206) Show / Hide 
Range on Protein: 477-679
Range on HMM: 1-206/206
Sequence Identity: 67% (140 aa)

IKTKLQISRIPFAEGAMRYAFYAKDTLLNQKLVVKLNKKQHKSDPTLNKADMIKDLESQFICQHIVNQFNDRVSEHVNTTENLKNFVHCYIYEFTDP-AH
||||..||.|||||||||||..||||.||||.|.|..|||||..|..||.|||||.||||.||||||.|||||||||.||.|..|||||||||.|.. .|
IKTKVRISNIPFAEGAMRYAYHAKDTYLNQKMVAKQYKKQHKQNPKINKEDMIKDIESQFVCQHIVNCFNDRVSEHVQTTANILNFVHCYIYEVTHHYNH

PFKFYQAENYIPGEYVKFNNNSGWCDLKFDEPGLLSQALSHFSYQVTEGYLMIVDLQGVG-GMLTDPQIHCLDQ-NRFGLGNLGYSGFFKFFMTHQCNKF
..|.|..||||.|.|.|.|||.|||.....|...||||.|||..|...||.|||||||.. ||||||||||||| ..|| |||||.|...|||||||||.
NIKYYFVENYIEGDYQKYNNNAGWCNQTDMEYNQLSQAFSHFTWQYSQGYCMIVDLQGNEDGMLTDPQIHCLDQSHKFGQGNLGYEGMLRFFMTHQCNKY

CKQLQL
|..|||
CQKLQL
Kinase 15769.AA Alpha 477-674 50 6.4e-144 412.49 In-house 1-215 (215) Show / Hide 
Range on Protein: 477-674
Range on HMM: 1-215/215
Sequence Identity: 50% (110 aa)

IKTKLQISRIPFAEGAMRYAFYAKDTLLNQKLVVKLNKKQHKSDPTLNKADMIKDLESQFICQHIVNQFNDRVSEHVNTTEN-------LKNFVHCYIYE
..||.|.|..||.|||||||..|.|..|.||.|.|..|||.||. . .....|||.|.|..|.|.|..||.|..|...||..       .|.||||||||
QCTKIQMSSYPFMEGAMRYAMHAWDCWLHQKMVKKQHKKQWKSF-KYVWHHWIKDVERQMVCHHCVREFNQRLWEQEYTTHFNQMKPQPIKQFVHCYIYE

FTDP-AHPFKFYQAENYIPGEYVKFNNNSGWCD-LKFD-EPGLLSQALSHFSYQVTEGYLMIVDLQ-GVG-GMLTDPQIHC---LDQ-NRFGLGNLGYSG
....  |..|.|..|||. |||.|.|||.||.| |..| |...|.||.||...|...|.||.|||| ||| ..||||||||   ||| ..|| ||.||.|
LIHCHNHNIKYYSVENYMEGEYQKYNNNAGWVDFLTDDNEFNQLMQAFSHWTWQYSNGQLMVVDLQWGVGEWKLTDPQIHCPAKLDQGMKFGDGNCGYEG

FFKFFMTH--QCNKFC
.|.||.||  |||..|
MFRFFYTHHVQCNHYC
Kinase 15769.AA Alpha_kinase 488-674 35 1.5e-80 278.71 Pfam 1-225 (225) Show / Hide 
Range on Protein: 488-674
Range on HMM: 1-225/225
Sequence Identity: 35% (81 aa)

FAEGAMRYAFYAKDT-----LLNQKLVVKLNKK----QHKSDPTLNKADMIKDLESQFICQHIVNQFNDRVSEHVNTTENLKNFVHCY-IYEFTDPAH--
||.||||..|...||      .||..|.|..||    . |...  .. ....| ..|.|||.....||.. .||.|   ... |..|. .||. |. .  
FAQGAMRWCFRMFDTWDPNWRNNQNCVAKWYKKIKNYNQKQSIYVEEDYYFQDCKMQMICQQWMEKFNQKLQEHNNPPPPIE-FYDCCIVYELEDHNKPD

------------PFKFYQAENYIPG-EYVKFNNNSGWC---DLKFDEPGLLSQALSHFSYQVTEGYLMIVDLQGVG--G---MLTDPQIHCLDQNR---F
              |.. .|.|| | |.||.|||.||.   . . |. . ..||.|||.|. ..|..|..|.||||  .   .|||||||. |.|.   |
CYQGFFSYRTDWGGKYWYMEPYIEGCEFVKYNNNYGWVYDNMDRNDPWNQYMQAFSHFTYHRSNGQMMVCDIQGVGYNNKCYYLTDPQIHTKDGNYEMDF

--GLGNLGYSGFFKFFM-THQCNKFC
  |.||||. |..|||  .|.||..|
DEGMGNLGQEGIEKFFQNQHKCNHIC
Alpha_kinase 15769.AA Alpha_kinase 474-674 28 8.4e-49 169.36 SMART 1-255 (255) Show / Hide 
Range on Protein: 474-674
Range on HMM: 1-255/255
Sequence Identity: 28% (74 aa)

HSEIKTKLQISRI----PFAEGAMRYAFYAKDT-------LLNQKLVVKLNKKQHKSDPTLNKADMIK--------DLESQFICQHIVNQFNDRVSEHVN
... . .  ...|    |||.|||| .....|.       . ....|.|. ||. | .   .. . ..        | | | .|.|..| || .. .  |
DNKWTCQETCVKIKEPKPFAKGAMRWCYWGCDWSEHMHCFCHGWECVAKYFKKEYKRTW--DEERYFHETLHLCLRDVEMQMMCKHWANEFN-QEAQ-HN

TTENLKNFVHCYIYEFT-------DPAHPFKF---------------YQAENYIPGEYVKFNNNSGWCDLKFD---------EPGLLSQALSHFSYQVTE
....   |. ||. .|.       |  .|  |               .  | .. ||.||.|||.|| .  .          | . . || ||..|. ..
PCPKKIDFIPCYVFHFPRRIPAEYDRNIPYWFSYRTTDQMMVMCCCIFHMEPFMEGEFVKYNNNNGWVNDCMRWTTTSQRRTEMFEYCQAFSHWTYEWSN

GYLMIVDLQGV----GG--MLTDPQIHCLD--QNRFGLGNLGYSGFFKFFMTHQCNKFC
. ....|.|||    |    .||||||  |     || ||||  |. ||| |||||..|
HQMLVCDIQGVIHKNGDLYYYTDPQIHTEDQNGYGFGMGNLGQEGIEKFFQTHQCNQIC
Kinase 15769.AA Alpha-Unclassified 583-674 34 1.4e-30 96.81 In-house 111-215 (215) Show / Hide 
Range on Protein: 583-674
Range on HMM: 111-215/215
Sequence Identity: 34% (36 aa)

ENYIPGEYVKFNNNSG--WCDLKF-DEPGLLSQALSHFSYQVTEGYLMIVDLQG-VG------GMLTDPQIHCLDQNRFGL-GNLGYSGFFKFFMTH--Q
| |. ||.||..||.|     .|  .| . . .. .|..|| | . . ..|||| |.        .|||||| ..|  .|. .| |. . ...|  |  |
EPYLIGEFVKYSNNTGKEINFVKWEYEAYQYCCTYQHWTYQWTNHCDIVCDLQGWVDENDKKTWKMTDPQIHTIRQRYQGFKTNCGMRFIDYWFNNHHVQ

CNKFC
||..|
CNHYC
Kinase 15769.AA ChaK 583-674 36 3e-12 44.72 In-house 123-219 (219) Show / Hide 
Range on Protein: 583-674
Range on HMM: 123-219/219
Sequence Identity: 36% (35 aa)

ENYIPGEYVKFNNNSGWCDLKFDEPGLLSQALSHFSYQVTEGYLMIVDLQGVGGMLTDPQIHCLDQNR-----FGLGNLGYSGFFKFFMTHQCNKFC
|... ||. |.||| |   .       .  | ||. |  | | |...||||||  |||| .   .. .     ||  |||      |   | ||  |
EKCMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKPEEKQSCDMVFGPANLGEDAIRNFRAKHHCNSCC