Gene 23071 (Tetrahymena)
23071
Sequence
Protein domains of 23071.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 23071.AA | CAMK-Unique | 85-360 | 36 | 6.8e-162 | 538.39 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 85-360 Range on HMM: 1-363/363 Sequence Identity: 36% (135 aa) YEKLEVIGEGGFGVVYKVLDRETKLIKAMKRLKK-----NKLIQ------------------TDNELELLKRLDHPNIIRIFDF----YQDEE------- |.....||.|.||.||...||||. ..|.|..|| .|..| ...|....|..||||||...|. ..|.. YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI --------DFYIITEYIEGGCLFDEIQKLSKRYFNFSIIKFDFNISLKKLKQQFNE--YHACQIMQQILMAVNYAHSINIVHRDLKAENVLIQYNEQE-- ..||..||..||.|||.|||....|||| |||||||| ||.....|.| ...|.|||..|.||.|.||..|||||||.||....|.... IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNF-IIKFDFNI-LKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNN ---------SRYHVKVIDWGLSVLVEHNQKLH---IDCGTSYFKAP--------------EVIN-RCYDEKC----DLWSCGALMYELLSGCPPFDAETD |..|.|..|.||.....||.. | ..|||....|| |||| .|||..| |.||.|..||..|.||||||.|.. HHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECE D--------EIEEKILQGGY-SLPTEYFGG---VSVEAIDLLKKLLTYIPSFRISAKQALEHSWF | ||.|.|..|.| ........| .|.||.|..|...|..|..|.|||..|||.|. DRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI |
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Kinase | 23071.AA | CAMK | 90-360 | 23 | 3.4e-107 | 346.54 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 90-360 Range on HMM: 1-425/425 Sequence Identity: 23% (105 aa) VIGEGGFGVVYKVLDRETK------------LIKAMKRLKKN-------------------------------KLIQTDNELELLKR-------LDHPNI ..|.|.||.|... ...|. |.| ..|. .. . .|.|..|. |||||| TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI IRIFDFYQD-------------------EEDFYIIT---EYIEGGCL----FDEIQKLSKRYFNFSIIKFDFNISLKKLKQQ--------FNEYHACQIM |.....|.| ....|... ||..||.| || |.. ......| . | |.| |.... IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEF-D--------------QFDIVERGRFTEREARRYF QQILMAVNYAHSINIVHRDLKAENVLIQYNEQESR------------YHVKVIDWGLSVLVEH------------------------NQKLHIDCGTSYF .||. ||.| || |||||||| ||.|...|. .| . .|.||.|.. ... .||.. ||| .. RQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEY KA-PEVINRC---------------YDEKCDLWSCGALMYELLSGCPPFDAE-------------TDDEIEEKILQGGYSLPTEYFGG------------ | |||.|.. |..||| |||| ..| .|.|.|||... .| |. |||..| |. | .|| . MAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDD VSVE--------AIDLLKKLLTYIPSFRISAKQALEHSWF .| | ..||..|.|.. |. |....|.|.| |. ISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | 23071.AA | Ciliate-E2a | 85-360 | 34 | 1.9e-94 | 278.41 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 85-360 Range on HMM: 1-275/275 Sequence Identity: 34% (102 aa) YEKLEVIGEGGFGVVYKVLDRETKLIKAMKRLKKNKLIQTD-------NELELLKRLDHPNIIRIFDFYQDEEDFYIITEYIEGGCLFDEIQKLSKRYFN |... .||.| ||.||.. ..|. .||| ..| |. |.. ||. ....|||||||.....|.|| .|...||.||| |.|.|.. . .. YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE FSIIKFDFNISLKKLKQQFNEYHACQIMQQIL-MAVNYAHSINIVHRDLKAENVLIQYNEQESR--YHVKVIDWGLSVLV--EHNQKLHIDCGTSYFKA- .. .|.||||.| ...| |. ||.||||| ||.|. . ..| .|.||.||. . ..... ||| .. | --------------------IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAP -----PEVINRC-YDEKCDLWSCGALMYELLSGCPPFDAETDDEIEEKILQGGYSLPTEY-FGGVSVEAIDLLKKLLTYIPSFRISAKQALEHSWF .||... ||.|||.||||. .| ||.|.|||...| .|| ... . ... . .| |..||.||.| . |. ||.|.|||.| || EVLNNKEVLKHKQYDTKCDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF |
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Kinase | 23071.AA | S_TKc | 85-360 | 34 | 6e-89 | 302.72 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 85-360 Range on HMM: 1-231/231 Sequence Identity: 34% (100 aa) YEKLEVIGEGGFGVVYKVLDRETKLIKAMKRLKKNKLIQTDNELELLKRLDHPNIIRIFDFYQDEEDFYIITEYIEG--GCLFDEIQKLSKRYFNFSIIK ||.|..||.|.||.|||. ...|. | |.|..| ... .|...||. .||||....|..|| ...|...||..| | ||| |.| .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRH-------- FDFNISLKKLKQQFNEYHACQIMQQILMAVNYAHSINIVHRDLKAENVLIQYNEQESRYHVKVIDWGLSVLVEHNQKLHIDCGTSYFKAPEVINRCYDE- .|...|.| ||. .|.||. |..| || .|.||||| ||.|. |.|..| ||. .. . ||| .. ||||. |. --------GLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL------TTFCGTPWYMAPEVL--GYGKC KCDLWSCGALMYELLSGCPPFDAETDDEIEEKILQGGYSLPTEYFGGVSVEAIDLLKKLLTYIPSFRISAKQALE-------HSWF ||| |||| ..||.|.|.|||. ..... .||. | ||.|...|.|.. |. |..| .||. | || KCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 23071.AA | CAMK1 | 85-360 | 34 | 1e-84 | 246.2 | In-house | 1-276 (276) | Show / Hide |
Range on Protein: 85-360 Range on HMM: 1-276/276 Sequence Identity: 34% (104 aa) YEKLEVIGEGGFGVVYKVLDRET---KL---IKAM--KR-LKKNKL---IQTDNELELLK---RLDHPNIIRIFDFYQDEEDFYIITEYIEGGCLFDEIQ || ..||.| |..||.. ..|| . ||.. |. .||.. . .||.| .| ..|||||| ....|.....||...|.. || ||| | YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDHPNIIKFYEWYESDNHFYLVMELVTGGELFDRIV KLSKRYFNFSIIKFDFNISLKKLKQQFNEYHACQIMQQILMAVNYAHSINIVHRDLKAENVLIQYNEQESRYHVK--VIDWGLSVLVEHNQ-KLHIDCGT . ...| .|. ||.||| ||.| || .||||||| || | | .. .| ..| ||| ..|. .. ||| EKG----------------------NYTEKDARHIMKQILSAVEYMHSKGIVHRDLKPENLL--YYDKDEDSKIKRSIADFGLSKIFDHDENLMKTACGT SYFKAPEVINR----CYDEKCDLWSCGALMYELLSGCPPFDAET-DDEIEEKILQGGYSLPTEYFGGVSVE-AIDLLKKLLTYIPSFRISAKQALEHSWF .. ||||... || .||.||.| | || |.||| .|. |.|. |||. . | |. ... .| . | |..|..|. |. |....|.|.| |. PGYVAPEVLECKKDKPYDKACDMWSIGVITYILLCGYPPFYDENVDNELFEKIKKCEYEFPSPWWDNISDQEAKDFIKHMLEVDPKKRYTCEQCLNHPWI |
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Kinase | 23071.AA | Ciliate-E2 | 85-360 | 25 | 1e-80 | 274.48 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 85-360 Range on HMM: 1-365/365 Sequence Identity: 25% (103 aa) YEKLEVIGEGGFGVVYKVLDRETK-----------------------LIKAMKRLKKNKLIQTDNELELLK----------------RLDHPNIIRIFDF |.....||.|.||.|||. ..... |.|||..|||...|. .|. ... .|.|||||..... YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC YQ--DEEDFYIITEYIEGGCLFDEIQ---KLSKRYFNFSIIKFDFNISLKKLKQQFNEYHACQIMQQIL---------------MAVNYAHSIN-IVHRD .| |.. .|...||..|| ||| |. | .. .. | ..|.|.....||.||| |..| || | |.||| FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIE------------K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRD LKAENVLIQYNEQESRYHVKVIDWGLSV-----------LVEHNQKLHID----------------------CGTSYFKAPEVINRC----------YDE .| ||.|. .|.||.||| ..... .. ||| ...|||..|. ||. IKPENILF----------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDY KCDLWSCGALMYELLSGCPPFDAETDDEIEEKILQGGYSLPTE--------------YFGGVSVEAIDLLKK----LLTYIPSFRIS-AKQALEHSWF |||.||.| ..||.|.| ||| ...|.|. ...| . . .| |..||.|| .| . |. ||. ..|.|.| || KCDIWSLGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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Kinase | 23071.AA | Pkinase | 85-360 | 31 | 3.2e-77 | 267.66 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 85-360 Range on HMM: 1-293/293 Sequence Identity: 31% (98 aa) YEKLEVIGEGGFGVVYKVLDRETKLIKAMKRLKKNKLIQTDN-------ELELLKRLDHPNIIRIFDFYQDEEDFYIITEYIEGG----CLFDEIQKLSK |.....||.|.||.||| .. | | |.|..|| . . |....|||.||||.|..|...|. . |...|| ||| ||| |. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--- RYFNFSIIKFDFNISLKKLKQQF--NEYHACQIMQQILMAVNYAHSINIVHRDLKAENVLIQYNEQESRYHVKVIDWGLSVL--VEHNQKLHIDCGTSYF . . | | ... .| ||| ...| || .|.||||| ||.|| | . . .||..|.||. . .|. .. |||... -----------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFDY-NNS-MTTFCGTPWY KAPEVIN--RCYDEKCDLWSCGALMYELLSGCPPFDAE------TDDEIEEKILQGGYSLPTEYFGGVS-----------------VEAIDLLKKLLTYI |||||. . |. |.| |||| ..||.|.| |||. . ..... ..|... .. . .. .| |..|..|..|.. MAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKD PSFRISAKQALEHSWF |. |..|.|.|.| || PKKRPTAEQILQHPWF |
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Kinase | 23071.AA | CDPK | 193-360 | 49 | 7.4e-77 | 235.29 | In-house | 97-271 (271) | Show / Hide |
Range on Protein: 193-360 Range on HMM: 97-271/271 Sequence Identity: 49% (87 aa) KQQFNEYHACQIMQQILMAVNYAHSINIVHRDLKAENVLIQYNEQES--RYHVKVIDWGLSVLVEHN-----QKLHIDCGTSYFKAPEVINRCYDEKCDL | .|.| |..||.||| ||||.|| |||||||| ||.| .... | | .||||||.| ..| .|. ||| | ||||... |.||||. KGHFTEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWVIYNIKVIDWGTSKKFDQNQKIEDKKMSQRCGTPYYIAPEVLQKKYNEKCDI WSCGALMYELLSGCPPFDAETDDEIEEKILQGGYSLPTEYFGGVSVEAIDLLKKLLTYIPSFRISAKQALEHSWF |||| .| ||.| ||| ...| || ||. | ||. . . .|.||.|| .|.|.| | |.|| |||.| || WSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF |
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Kinase | 23071.AA | CAMKL | 85-360 | 30 | 6e-74 | 235.33 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 85-360 Range on HMM: 1-297/297 Sequence Identity: 30% (97 aa) YEKLEVIGEGGFGVVYKVLD-RETKLIKAMKRLKKNKLI----QTDN--------------ELELLKRLD---HPNIIRIFDFYQDEED------FYIIT |. ....|.|.||.| .. | |. |.| ..|.|. ..| | ...|.|. |||||.... ....| .|... YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM EYIEGGC--LFDEIQKLSKRYFNFSIIKFDFNISLKKLKQQFNEYHACQIMQQILMAVNYAHSINIVHRDLKAENVLIQYNEQESRYHVKVIDWGLSVLV ||..|| ||| |.| .| . . | |... .||. |||| || .|||||.|.||.|. .| . .|.|| |.| . EYCSGGEMDLFDYIVKHGHRR------------------GRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNN---NIKIIDFGFSNMY E-H----NQKLHIDCGTSYFKAPEVINR--C-YD-EKCDLWSCGALMYELLSGCPPFDAETDD-------EIEEKILQGGYSLPTEYFGGVSVEAIDLLK . . .|||.. ||. . |||.... || | | |||| ..| .. | |||..|. . ..|| .| | | |. || ...||.. RPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYH--VS-DCRDLIR KLLTYIPSFRISAKQALEHSWF |.|. |. |....| ..| |. KMLQVNPEKRPTIHQIMNHPWM |
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Kinase | 23071.AA | Ciliate-E2-Unclassified | 85-360 | 26 | 1.8e-70 | 240.42 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 85-360 Range on HMM: 1-352/352 Sequence Identity: 26% (99 aa) YEKLEVIGEGGFGVVYKVLDRETKLIKAMKRLKKNKLIQ---------------TDNELE-------------LLKRLDHPNIIRIFDFYQDEEDFYIIT |.....||.||||.|||. ....|.. ||| .||.. . . |... .|. ..||.|.. |. ||.. .||.. YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM EYIEGGCLFDEIQKLSK---RYFNFSIIKFDFNISLKKL-------KQQFNEYHAC-----QIMQQILMAVNYAHSIN-IVHRDLKAENVLIQYNEQESR ||.||| |.. |.| .| ... ...| |..|. ... ||| . .| |. | |.|||.| ||.|.. | . . EYCEGGDLWQYIKKRKKQKQK---------------GNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK--N YHVKVIDWGLSVLVEHN----------------QKLHIDCGTSYFK----APEVINR-CYD----EKCDLWSCGALMYELLSGCPPFDAETDDE------ |..|.||.|.| . | |... ||| ... ||||. . || .||| ||.| ..||.| | .||....... YYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLIT ----------IEEKILQGGYSLPTEYF----GGVSVEAIDLLK----KLLTYIPSFRISAKQALEHSWF ....|.|. .. | . . ..| ||.|... |.| . |. ||...|.|.| || QWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | 23071.AA | RSK | 189-360 | 35 | 4.9e-53 | 182.52 | In-house | 92-278 (278) | Show / Hide |
Range on Protein: 189-360 Range on HMM: 92-278/278 Sequence Identity: 35% (68 aa) LKKLKQQ--FNEYHACQIMQQILMAVNYAHSINIVHRDLKAENVLIQYNEQESRYHVKVIDWGLSVL--VEHNQKLHIDCGTSYFKAPEVIN----RC-Y |.| |. | | ||..| .| .|| . |. |.||||| ||.| . .. |.|..| |.. . .|||... |.| . |||... .. . LQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDES--NEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGH DEKCDLWSCGALMYELLSGCPPFDA---ETDDEIEEKILQGGYSLPTEYFGGVSVEAIDLLKKLLTYIPSFRIS-----AKQALEHSWF |. ||.|| |.||||.|.||||| . .. .|| ..|..| .||. . .| || ||..|.|. |. |.. |.. ..|.|| DKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF |
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Kinase | 23071.AA | MARK | 201-360 | 40 | 6.5e-49 | 158.12 | In-house | 106-262 (262) | Show / Hide |
Range on Protein: 201-360 Range on HMM: 106-262/262 Sequence Identity: 40% (67 aa) ACQIMQQILMAVNYAHSINIVHRDLKAENVLIQYNE-QESRYHVKVIDWGLSVLVEHNQKLHIDCGTSYFKAPEVIN-RCYD-EKCDLWSCGALMYELLS | .| .||. |||| ||.||||||.|.||.|| | . .| || |.|. .. .||| . ||| . |||... . || | | ||.| ..| ... ARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNH----NIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVC GCPPFDAET--DDEIEEKILQGGYSLPTEYFGGVSVEAIDLLKKLLTYIPSFRISAKQALEHSWF |. |||. | . |...||| | |. |. ||.|. .|...||| |. |..... ..|.|. GYFPFDGDTQDYKELYKKILRGKYDIPCH----VSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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Kinase | 23071.AA | CDPK | 85-173 | 42 | 9.6e-35 | 104.15 | In-house | 1-99 (271) | Show / Hide |
Range on Protein: 85-173 Range on HMM: 1-99/271 Sequence Identity: 42% (42 aa) YEKLEVIGEGGFGVVYKVLDR-ETKLIK-AMKRLKKNKLIQTD------NELELLKRLDHPNIIRIFDFYQDEEDFYIITE--YIEGGCLFDEIQKLSK | . .|.|.|.||.|.|| .. |. .. ||| .|..... . ||.|.|| |||||||.|. ||||| .||..| | .|| ||| |. .. YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGH |
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Kinase | 23071.AA | MARK | 85-175 | 33 | 1.9e-21 | 67.02 | In-house | 1-100 (262) | Show / Hide |
Range on Protein: 85-175 Range on HMM: 1-100/262 Sequence Identity: 33% (33 aa) YEKLEVIGEGGFGVVYKVLDRETKLIKAMKRLKKNKLIQ------TDNELELLKRLDHPNIIRIFDFYQ--DEED-FYIITEYIEGGCLFDEIQKLSKRY |. | .||.|....|...... |. | | ..|.|| |.|..|.|||||||. |. . .|. .|.| ||..|| |.| |.. .... YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR |
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Kinase | 23071.AA | RSK | 88-170 | 37 | 1.9e-17 | 60.65 | In-house | 1-94 (278) | Show / Hide |
Range on Protein: 88-170 Range on HMM: 1-94/278 Sequence Identity: 37% (35 aa) LEVIGEGGFGVVYKVLDR---ETKLIKAMKRLKKNKLIQTD-------NELELLKRLD-HPNIIRIFDFYQDEEDFYIITEYIEGGCLFDEIQK |.| |.||.| |. . |. | ||| |||.|..|.. | . |.| ||.|.. .. .|.|. .|.|.||..|| ||. .|| LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQK |
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Kinase | 23071.AA | TyrKc | 85-360 | 22 | 9.9e-17 | 47.84 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 85-360 Range on HMM: 1-280/280 Sequence Identity: 22% (70 aa) YEKLEVIGEGGFGVVYK-VLDRETKLIKAMKRLKKNKLIQTDNELELLKRL--DHPNIIRIFDFYQDE-------EDFYIITEYIEGGCLFDEIQKLSKR ......||| ||.||| ... . | | ||.... .|......| .||||.|.. .. | .|..|| ..|.| | ..| .. ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK YFNFSIIKFDFNISLKKLKQQFNEYHACQIMQQILMAVNYAHSINIVHRDLKAENVLIQYNEQESRYHVKVIDWGLSVLVEHN------QKLHID----C .. . .... || .| || |..|||| | |.|. | .||. | ||| ... .. . ---------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKG GT--SYFK--APEVI-NRCYDEKCDLWSCGALMYELLSGCPPFDAE------TDDEIEEKILQGGYSLPTEY-----FGGVSVEAIDLLKKLLTYIPSFR | . |||.| ... .| | || | .|.|... . . . ...|. |.. ||.. . .. | . . | .. |. . |. | GKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDR ISAKQALEHSWF . .. |. | PTFSEI--HECF |
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Kinase | 23071.AA | Pkinase_Tyr | 85-232 | 28 | 5.5e-11 | 37.83 | Pfam | 1-144 (270) | Show / Hide |
Range on Protein: 85-232 Range on HMM: 1-144/270 Sequence Identity: 28% (46 aa) YEKLEVIGEGGFGVVYKVLDR----ETKLIKAMKRLKKNKLIQTD-------NELELLKRL-DHPNIIRIFDFYQ-DEED--FYIITEYIEGGCLFDEIQ ......||| ||.||| . .||. | | | |.. . . .|....| | .||||.| ..| ||..|| ..|.| | . ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR KLSKRYFNFSIIKFDFNISLKKLKQQFNEYHACQIMQQILMAVNYAHSINIVHRDLKAENVLI | . ||... . .|. .|| .. .| .|.|..|||| | |.|. KHR------------------EDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLV |
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Kinase | 23071.AA | Pkinase_Tyr | 271-322 | 36 | 0.030441 | 8.22 | Pfam | 182-236 (270) | Show / Hide |
Range on Protein: 271-322 Range on HMM: 182-236/270 Sequence Identity: 36% (20 aa) APEVIN-RCYDEKCDLWSCGALMYELLSGC-PP-FDAETDDEIEEKILQGGYSLP |||.|| . . .| | || | ||.|... . | . .. |. |.| . || .| APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMP |
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Efhand | 23071.AA | efhand | 409-437 | 37 | 3.2e-07 | 30.86 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 409-437 Range on HMM: 1-29/29 Sequence Identity: 37% (11 aa) QLTNLFNQIDKDQDGKISHEEMAQALKSV .| ..|...|||.||.|. ||. ...|.. ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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EFh | 23071.AA | EFh | 409-437 | 37 | 1e-06 | 29.42 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 409-437 Range on HMM: 1-29/29 Sequence Identity: 37% (11 aa) QLTNLFNQIDKDQDGKISHEEMAQALKSV .. .|. .||| ||.|. ||. ...||. EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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EFh | 23071.AA | EFh | 459-487 | 24 | 1.7e-05 | 25.54 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 459-487 Range on HMM: 1-29/29 Sequence Identity: 24% (7 aa) EISEIINHIDFNQNGEIEYTEFLVAAMRK |. |.....| . .|.|.. ||... ... EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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Efhand | 23071.AA | efhand | 459-487 | 24 | 2.7e-05 | 23.77 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 459-487 Range on HMM: 1-29/29 Sequence Identity: 24% (7 aa) EISEIINHIDFNQNGEIEYTEFLVAAMRK |. |.....| ...|.|.. ||. . ... ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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Efhand | 23071.AA | efhand | 495-523 | 37 | 6e-06 | 26.3 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 495-523 Range on HMM: 1-29/29 Sequence Identity: 37% (11 aa) FLYKVFDIFDKDGDGFISLQEVKDKLQNN | ..|..|||||||.|...| .. ... ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |
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EFh | 23071.AA | EFh | 495-523 | 41 | 6.6e-05 | 23.55 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 495-523 Range on HMM: 1-29/29 Sequence Identity: 41% (12 aa) FLYKVFDIFDKDGDGFISLQEVKDKLQNN . ..|..|||||||.|...| || ... EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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EFh | 23071.AA | EFh | 533-561 | 31 | 3e-06 | 28.18 | SMART | 1-29 (29) | Show / Hide |
Range on Protein: 533-561 Range on HMM: 1-29/29 Sequence Identity: 31% (9 aa) VWNQIIKEVDEDGDKEISFDEFKSIINTY ........| ||| .|.|.||| .. . EFKEMFRMFDKDGDGYIDFEEFKDMMKSL |
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Efhand | 23071.AA | efhand | 533-561 | 34 | 3e-06 | 27.36 | Pfam | 1-29 (29) | Show / Hide |
Range on Protein: 533-561 Range on HMM: 1-29/29 Sequence Identity: 34% (10 aa) VWNQIIKEVDEDGDKEISFDEFKSIINTY .....||.| ||| .|.|.||.... . ELKEMFKEFDKDGDGYIDFEEFCEMMKKL |