22014

Species: Tetrahymena
Alias: PreTt22014, 213.m00064, TTHERM_01052910, 22014, 817
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: CDPK

Sequence

Name Sequence Type Origin Length Description Download
22014.AA Protein None 537 None Fasta, JSON
22014.kin_dom Protein Kinase Domain None 270 None Fasta, JSON
22014.NA RNA None 1614 None Fasta, JSON

Protein domain

Protein domains of 22014.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 22014.AA CDPK 65-334 37 1.1e-152 471.49 In-house 1-271 (271) Show / Hide
Range on Protein: 65-334
Range on HMM: 1-271/271
Sequence Identity: 37% (104 aa)

YFFERHLAQGEFGDIRIVKHK-KTGQSR-ALKIVAKNKLGVKEK--QVLNEIKILSKLDHPNIIKLYEYYQDRYAYYLIFE--LLLGGQLIEYIQETSYL
|.....|..|.||..|.|||| ||.|.| | ||..|...  ||.  |..|||.||..||||||||.||.|||.. ||...|  .. ||.|..||.|....
YKIKKVLGKGHFGQVRKVKHKQKTNQERVAMKIIPKSRVKDKEQQQQFFNEIEILKQLDHPNIIKIYEFYQDEKNYYIVMETEYCTGGELFDYIIEKGHF

PETQSASIVQQLLSAINYCHQQKITHLNITPQNILLNIDEETNQVSIKQYVIIVQDLIKKQPIQALKIQSFEENDTFSEQINNITYKSPEEINKSYNYLA
.|...|.|..|.|||.||||...|.| ...|.|||.........| |.....|.....||.. . .||    |....|.......| .|| ..|.||. .
TEKEAAYIMRQILSAVNYCHSNNIVHRDLKPENILFDSKKDDSWV-IYNIKVIDWGTSKKFDQN-QKI----EDKKMSQRCGTPYYIAPEVLQKKYNEKC

DVWSIGVIWFLILMGVPPFYGINRKKTIEAIQNIQMRYS-CGFSIKHDSQIQEIFKKIFVSQDQRMKCQDILDHQYF
|.||.|||.. .|.|.||||| |.....|.........  . .....|.... |.|........||..|..|.|..|
DIWSCGVILYILLCGYPPFYGKNDQEIMEKVKKGKYSFEGPEWDHISDEAKDLIRKMLCYDPKKRMSAQQALQHPWF

Kinase 22014.AA CAMK 70-334 20 5.2e-65 208.14 In-house 1-425 (425) Show / Hide
Range on Protein: 70-334
Range on HMM: 1-425/425
Sequence Identity: 20% (87 aa)

HLAQGEFGDIRIVKHKKTG------------QSRALKIVAKNKLGV---------------------------KEKQVLNEIKILSK-------LDHPNI
 | .| ||  . ..||.|.            |  | ||. |.||                             ..|.|..||.|..|       ||||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IKLYEYYQD-------------------RYAYYLIF---ELLLGG----QLIEYIQETSY---------------LPETQSASIVQQLLSAINYCHQQKI
|||||.|.|                   .  .|...   |.  ||     | .||.| ..               ..| . . ...|..||..|||...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

THLNITPQNILLNIDEETNQVSI--------KQYVIIVQDLIKKQPIQALKI----------------QSFEENDTFSEQINNITYKS-PEEINKS----
 |. . | ||||. ... ... .        ... | . |    . ..  .                  ...|.. ....     | . || .|..    
VHRDLKPENILLDDNNDDSDP-VEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

-----------YNYLADVWSIGVIWFLILMGVPPFYGI-------------NRKKTIEAIQNIQMR-YSCGFSI------------KHDS-------QIQ
           |.. .|.||.||| .  | | |||||              | ... | |.. . . ..  ||.              |.       . .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

EIFKKIFV-SQDQRMKCQDILDHQYF
   .|. .   ..||.....|.|. .
DLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 22014.AA S_TKc 65-334 23 1.1e-48 168.99 SMART 1-231 (231) Show / Hide
Range on Protein: 65-334
Range on HMM: 1-231/231
Sequence Identity: 23% (69 aa)

YFFERHLAQGEFGDIRIVKHKKTGQSRALKIVAKNKLGVKEKQVLNEIKILSKLDHPNIIKLYEYYQDRYAYYLIFELLLG--GQLIEYIQETSY-----
| . |.. .| ||  . ..|||||.  |.||.         .....||.||.| .||||.|||...||   .|...|.. |  | | .||..  .     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LPETQSASIVQQLLSAINYCHQQKITHLNITPQNILLNIDEETNQVSI------KQYVIIVQDLIKKQPIQALKIQSFEENDTFSEQINNITYKSPEEI
 .|| . .....|...|..|||...| |  . |.||||.      .. |      .|.                           . ..    | .|| .
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-----HIKICDFGLARQL---------------------------TTFCGTPWYMAPEVL

NKSYNY-LADVWSIGVIWFLILMGVPPFYGINRKKTIEAIQNIQMRYSCGFSIKHDSQIQEIFKKIFV-SQDQRMKCQDILD-------HQYF
  .|..  .|.||.|.| .  | | |||.      ..... .. .          ...  .. .|...   ..|. . ..|        |..|
--GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 22014.AA Ciliate-E2a 65-206 36 2.1e-48 140.59 In-house 1-149 (275) Show / Hide
Range on Protein: 65-206
Range on HMM: 1-149/275
Sequence Identity: 36% (55 aa)

YFFERHLAQGEFGDIRIVKHKKTGQSRALKIVAKNKLGVKE---KQVLNEIKILSKLDHPNIIKLYEYYQDRYAYYLIFELLLGGQLIEYIQETSYLPET
|.|.. . .| ||  ....||.||. .| |.. | |. ...   ... |||.|...|||||||||||.|.|   |||..|.. ||.|...|..   . | 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEE

--QSASIVQQLLS-AINYCHQQKITHLNITPQNILLN-IDEET-NQVSIK
  . ..| ||||. ...|.||..| |  . |.|||.. .. .   .  ||
IQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIK

Kinase 22014.AA Ciliate-E2 65-334 20 1.2e-43 147.75 In-house 1-365 (365) Show / Hide
Range on Protein: 65-334
Range on HMM: 1-365/365
Sequence Identity: 20% (85 aa)

YFFERHLAQGEFGDIRIVKHKKTG-----------------------QSRALKIVAKN--KLGVKEKQVLNEIK----------ILSKLDHPNIIKLYEY
| | . . || ||... .|..|..                       .  |.||. ||  .   .|.....||.          ||..|.||||||.||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

YQ--DRYAYYLIFELLLGGQLIEYIQ------------ETSYLPETQSASIVQQLLS---------------AINYCHQQK-ITHLNITPQNILLNIDEE
.|  |.  .||..|.. || | .||.            .  |. | . . | .|.|.               |..|.|... | | .| |.|||.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

TNQVSIKQYVIIVQDLIKKQPIQALKIQSFEENDTFSEQINNIT--------------------------------------YKSPEEIN-KS-------
                        .||  |     .... .|.|                                      |..|| .| |.       
------------------------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQ

--YNYLADVWSIGVIWFLILMGVPPFYGINRKKTIEAIQNIQMRYSCGFS------------------IKHDSQIQEIFKK-----IFVSQDQRMK-CQD
  |.| .|.||.||| .  |.| |||            |....   . |.                   |.. . . ..||     . . ...|.   ..
KGYDYKCDIWSLGVILYEMLFGKPPF------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQ

ILDHQYF
||.|..|
ILNHPWF

Kinase 22014.AA Ciliate-E2-Unclassified 65-334 19 2.3e-41 141.22 In-house 1-352 (352) Show / Hide
Range on Protein: 65-334
Range on HMM: 1-352/352
Sequence Identity: 19% (71 aa)

YFFERHLAQGEFGDIRIVKHKKTGQSRALKIVAKNKLGVKEKQ-----------VLNEIK-------------ILSKLDHPNIIKLYEYYQDRYAYYLIF
| . . . || ||... ..|||..|  |.|.  |..   . ..            .|..|             ||. ..||.|.|.... ||.   |.. 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

ELLLGGQLIEYIQETSY-----------------LPETQSA-----SIVQQLLSAINYCHQQK-ITHLNITPQNILLNIDEETNQVSIKQYVIIVQDLIK
|.. || |..||.. .                  ..| |..      .  |.|....|.|... | | .|.|.|||.. . .      . |. |    | 
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK------NYYIKIIDFGIS

KQPIQALKIQSFEE--------NDTFSEQINNITYK----SPEEINK-SYN----YLADVWSIGVIWFLILMGVPPFYGINRKK------------TIEA
|...|  ... ..         .. .. .. .. |.    .|| . .  |.    | .|.|| ||| . .|.| .|||. |...            ... 
KKYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQ

IQNIQMRY-SCGFS--------IKHDSQIQEIF----KKIFVSQDQRMKCQDILDHQYF
......    . ..        . .....  |     |.. . ...|.  ..|| |..|
LYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 22014.AA Aur 65-184 36 5.3e-37 94.77 In-house 1-124 (257) Show / Hide
Range on Protein: 65-184
Range on HMM: 1-124/257
Sequence Identity: 36% (45 aa)

YFFERHLAQGEFGDIRIVKHKKTGQSRALKIVAKNKLGVK--EKQVLNEIKILSKLDHPNIIKLYEYYQDRYAYYLIFELLLGGQLIEYIQET--SYLPE
  . ..| .| ||. . ..||||..  |||.. |. .  .  |.|. .|||| |.|.||||.|.| |..| . .||| |   ||.| ...|      ..|
FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE

TQSASIVQQLLSAINYCHQQKITH
 ..| ...|. .|..||| ..| |
QRAAKYMYQICNALDYCHSKNIIH

Kinase 22014.AA CAMKL 65-197 31 5.1e-36 112.33 In-house 1-163 (297) Show / Hide
Range on Protein: 65-197
Range on HMM: 1-163/297
Sequence Identity: 31% (52 aa)

YFFERHLAQGEFGDIRIVKH-KKTGQSRALKIVAKNKLGVKEKQVLN--------------EIKILSKLD---HPNIIKLYEYYQDRYA------YYLIF
| ... | .| ||  .  .| . ||.  | ||. |.|.  ...   |              ||.|...|.   ||||||||| ....        .||. 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELLLGGQ--LIEYIQETSY----LPETQSASIVQQLLSAINYCHQQKITHLNITPQNILLNID
|.  ||   | .||..  .    .|| .   . .|..||.||||...| |  | | ||||  .
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDEN

Kinase 22014.AA DCAMKL 65-206 30 3.7e-35 106.43 In-house 1-159 (279) Show / Hide
Range on Protein: 65-206
Range on HMM: 1-159/279
Sequence Identity: 30% (49 aa)

YFFERHLAQGEFGDIRIVKHKKTG-QSRALKI-----------------VAKNKLGVKEKQVLNEIKILSKLDHPNIIKLYEYYQDRYAYYLIFELLLGG
|   |    | | ..  ..|..|| .. |.||                 ..|.|.  ||. . ||..|..|..||.||.||| .  .  |||..|.  ||
YQIGRIIGDGNFAVVHECRHRETGDHKYAMKIRYQSTLQFSFPSKFFQQIDKRKCKGKEHMIDNEVSIMQKIKHPHIIQLYEHWDTETHYYLVMEYVQGG

QLIEYIQETSYLPETQSASIVQQLLSAINYCHQQKITHLNITPQNILLNIDEETNQVSIK
 | . | |.   .| ..| .. .| .|..| |   | |  | | | |.. .|   ..|.|
DLFDAITENTKFTERDAAIMMTCLCKALKYLHEMNIVHRDIKPENLLVCKHEDG-EKSLK

Kinase 22014.AA MARK 65-194 38 1e-33 107.69 In-house 1-137 (262) Show / Hide
Range on Protein: 65-194
Range on HMM: 1-137/262
Sequence Identity: 38% (53 aa)

YFFERHLAQGEFGDIRIVKHKKTGQSRALKIVAKNKLG--VKEKQVLNEIKILSKLDHPNIIKLYEYYQ--DRYA-YYLIFELLLGGQLIEYIQET--SY
| . . . .| ..  . . ||.||.  |.||. |.||    . | |  ||.|..||||||||||... .  ..    ||| |.  || | .||..    .
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LPETQSASIVQQLLSAINYCHQQKITHLNITPQNILL
|.|     | .|..||.||||.. | |  | |.|||.
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILI

Kinase 22014.AA CAMK-Unique 65-195 25 1.1e-33 108.38 In-house 1-191 (363) Show / Hide
Range on Protein: 65-195
Range on HMM: 1-191/363
Sequence Identity: 25% (49 aa)

YFFERHLAQGEFGDIRIVKHKKTGQSRALKIVAKNKLG-VKEKQ------------------VLNEIKILSKLDHPNIIKLYEY----YQDRY-------
| . | . .|.|| ..... ..||  .| |.| | . |  | ||                    .|. |. ..|||||||||..    ..||        
YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI

--------AYYLIFELLLGGQLIEYIQE--------------------TSYLPE--TQSASIVQQLLSAINYCHQQKITHLNITPQNILLN
        ..|.. |.. || | ..||.                      .. |  .....|.|.||||..| |.|.| | .. . ||...
IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVC

Kinase 22014.AA Pkinase 65-195 30 1.3e-29 105.82 Pfam 1-142 (293) Show / Hide
Range on Protein: 65-195
Range on HMM: 1-142/293
Sequence Identity: 30% (43 aa)

YFFERHLAQGEFGDIRIVKHKKTGQSRALKIVAKNKLGVKE-KQVLN--EIKILSKLDHPNIIKLYEYYQDRYAYYLIFELLLGG----QLIEYIQ---E
| ..| . .| ||  .. .||.||.  |.||. | .   .. .. ..  ||.|. .|.||||..||....|.  .|...|.. ||     | .||.   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

TSY-LPETQSASIVQQLLSAINYCHQQKITHLNITPQNILLN
... ..| .  ... |.|....|||...| |  . |.|||..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID

Kinase 22014.AA Ciliate-E2a 244-334 25 5.6e-11 28.58 In-house 182-275 (275) Show / Hide
Range on Protein: 244-334
Range on HMM: 182-275/275
Sequence Identity: 25% (24 aa)

YKSPEEIN-KSYNYLADVWSIGVIWFLILMGVPPFYGINRKKTIEAIQNIQMRYSCGF-SIKHDSQIQEIFKKIFVSQ-DQRMKCQDILDHQYF
....|... |.| .  |.||.||| .. |.| |||.| . . ... . . .  ..|     | ... . . ||  . .  .| ..|..|.|..|
LNNKEVLKHKQYDTKCDMWSCGVIFYILLCGKPPFKGKTYNEILQQNKKCKIDFNCPECWEKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF

Kinase 22014.AA Aur 251-297 22 9.3e-11 24.09 In-house 175-223 (257) Show / Hide
Range on Protein: 251-297
Range on HMM: 175-223/257
Sequence Identity: 22% (11 aa)

NKSYNYLADVWSIGVIWFLILMGVPPFYG-INRKKTIEAIQ-NIQMRYS
......  |.|..||. .  . | |||..  |...|...|. . . ...
GQMHDHKVDIWCLGVLCYELCHGCPPFESNENHDETYDRIKNKVDIQFP

Kinase 22014.AA TyrKc 65-334 17 9.6e-10 -65.09 SMART 1-280 (280) Show / Hide
Range on Protein: 65-334
Range on HMM: 1-280/280
Sequence Identity: 17% (55 aa)

YFFERHLAQGEFGDIRIVKHKKTGQSRALKIVAKNKLGVKEKQVLNEIKILSKL--DHPNIIKLYEYYQDR-------YAYYLIFELLLGGQLIEYIQET
  ... |  |.|| ..  . |   .  | | . ...    ..  ..|..|..||  .||||..|| .  .          .....|.  .| | .|....
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

SY-LPETQSASIVQQLLSAINYCHQQKITHLNITPQNILLNIDEETNQVSIKQYVIIVQDLIKKQPIQALKI-------QSFEE------NDTFSEQ---
   |.  .  |.  |  .  .| |.... |  .   |.|.. .                           ||          ..       |. . .   
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH------------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHK

INN--ITYK--SPEEINKS-YNYLADVWSIGV-IWFLILMGVPPFYGINR--KKTIEAIQNIQMRYSCGFSIK--------HDSQIQEIFKKIFVS-QDQ
  .  . ..  .|| ||.. ..   |||| || .| .   | .| .|.    .. .|.|.... .|                 . . .| |.      ..
GGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPED

RMKCQDILDHQYF
|   ..|  |..|
RPTFSEI--HECF

Kinase 22014.AA CAMK-Unique 244-334 20 1.4e-08 24.18 In-house 241-363 (363) Show / Hide
Range on Protein: 244-334
Range on HMM: 241-363/363
Sequence Identity: 20% (25 aa)

YKSP--------------EEIN-KSYNYLA----DVWSIGVIWFLILMGVPPFYGINRK--------KTIEAIQNIQM-RY-SCGFSI---KHDSQIQEI
|..|              | ||   | .      | ||.||| .. | | |||.. . .        ...|.|   .  .. .  ...   . .. .. .
YMAPEIVFCKNYQEMTRDEVINMQCYDQQCSPASDIWSLGVIMYYMLCGCPPFDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFV

FKKIFVSQDQRMKCQDILDHQYF
 .   | .|.| ..  .|.||..
KCCMTVDPDHRWSAKELLEHQWI

Kinase 22014.AA CAMKL 244-334 22 9e-06 14.3 In-house 199-297 (297) Show / Hide
Range on Protein: 244-334
Range on HMM: 199-297/297
Sequence Identity: 22% (23 aa)

YKSPEEINK---SYN-YLADVWSIGVIWFLILMGVPPFYGIN----RKKTIEAIQNIQMRYSCGFSIK-HDSQIQEIFKKIFVS-QDQRMKCQDILDHQY
| .|| ...   .|. . .|.||.||| . .. |  || . .     |. |    ...|.  . . |  | |. . . .|. .   ..|.....|. |  
YMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVSDCRDLIRKMLQVNPEKRPTIHQIMNHPW

F
.
M

Kinase 22014.AA Pkinase_Tyr 65-154 24 1e-05 20.04 Pfam 1-100 (270) Show / Hide
Range on Protein: 65-154
Range on HMM: 1-100/270
Sequence Identity: 24% (25 aa)

YFFERHLAQGEFGDIRIVKHK----KTGQSRALKIVAKNKLGVKE---KQVLNEIKILSKL-DHPNIIKLYEYYQ-DRYA--YYLIFELLLGGQLIEYIQ
  | . | .|.||...  . |    .|..  | |.. |..   ..   .  ..|.||...| .||||..||     ..    .|...|.  .| | .| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

E
.
K

Kinase 22014.AA Pkinase 242-295 31 0.000135 17.33 Pfam 175-233 (293) Show / Hide
Range on Protein: 242-295
Range on HMM: 175-233/293
Sequence Identity: 31% (19 aa)

ITYKSPEEIN--KSYNYLADVWSIGVIWFLILMGVPPFYGI----NRKKTIEAIQNIQMR
. | .|| |.  . | . .|.||.|.| .  | | |||.|     |    .. |..| ..
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGP

Kinase 22014.AA MARK 252-334 24 0.000966 8.3 In-house 180-262 (262) Show / Hide
Range on Protein: 252-334
Range on HMM: 180-262/262
Sequence Identity: 24% (21 aa)

KSYN-YLADVWSIGVIWFLILMGVPPFYGIN--RKKTIEAIQNIQMRYSCGFSIKHDSQIQEIFKKIFVSQDQRMKCQDILDHQYF
| |. . .|.|| ||. . .. |  || | .   |.  . |.. . .. |  | .  . || ...   |  ..|.....|. |  .
KPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLT---VNPEERPTIEEIMKHPWM

Kinase 22014.AA DCAMKL 259-277 52 0.002179 5.79 In-house 201-219 (279) Show / Hide
Range on Protein: 259-277
Range on HMM: 201-219/279
Sequence Identity: 52% (10 aa)

DVWSIGVIWFLILMGVPPF
|.|..|||   .| | |||
DIWAAGVILYILLCGFPPF

Kinase 22014.AA efhand 333-344 41 8.190197 3.73 Pfam 1-12 (29) Show / Hide
Range on Protein: 333-344
Range on HMM: 1-12/29
Sequence Identity: 41% (5 aa)

YFKDIFQEFDQN
 .|..|.|||..
ELKEMFKEFDKD

Efhand 22014.AA efhand 395-423 27 0.000116 21.48 Pfam 1-29 (29) Show / Hide
Range on Protein: 395-423
Range on HMM: 1-29/29
Sequence Identity: 27% (8 aa)

KLTEDFQRIDVNKDGQLSREEIRSGFEGF
.| | |. .|...||....|| ..... .
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL

EFh 22014.AA EFh 395-423 24 0.002715 17.19 SMART 1-29 (29) Show / Hide
Range on Protein: 395-423
Range on HMM: 1-29/29
Sequence Identity: 24% (7 aa)

KLTEDFQRIDVNKDGQLSREEIRSGFEGF
.. | |. .|...||... || . ..  .
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL

Efhand 22014.AA efhand 434-462 31 8e-07 29.38 Pfam 1-29 (29) Show / Hide
Range on Protein: 434-462
Range on HMM: 1-29/29
Sequence Identity: 31% (9 aa)

FLDELFQKIDCNKNGYINYNEFISVAMDK
 |.|.|...| ...|||...||... ...
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL

EFh 22014.AA EFh 434-462 27 8.7e-07 29.8 SMART 1-29 (29) Show / Hide
Range on Protein: 434-462
Range on HMM: 1-29/29
Sequence Identity: 27% (8 aa)

FLDELFQKIDCNKNGYINYNEFISVAMDK
 ..|.|...| ...|||...||. . . .
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL

Efhand 22014.AA efhand 470-498 34 2e-06 27.78 Pfam 1-29 (29) Show / Hide
Range on Protein: 470-498
Range on HMM: 1-29/29
Sequence Identity: 34% (10 aa)

KLKQAFSYFDQDQNGFITKEELFQSLQSQ
.||..|. ||.|..|.|..||. . ....
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL

EFh 22014.AA EFh 470-498 34 2.1e-05 25.23 SMART 1-29 (29) Show / Hide
Range on Protein: 470-498
Range on HMM: 1-29/29
Sequence Identity: 34% (10 aa)

KLKQAFSYFDQDQNGFITKEELFQSLQSQ
..|..|. ||.| .|.|..||. . ..| 
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL

Efhand 22014.AA efhand 508-536 31 2.4e-07 31.28 Pfam 1-29 (29) Show / Hide
Range on Protein: 508-536
Range on HMM: 1-29/29
Sequence Identity: 31% (9 aa)

MWQTILEKGDKNKDGKLSYQEFIDMLKQL
... . .. ||..||.....||..|.|.|
ELKEMFKEFDKDGDGYIDFEEFCEMMKKL

EFh 22014.AA EFh 508-536 34 2e-06 28.87 SMART 1-29 (29) Show / Hide
Range on Protein: 508-536
Range on HMM: 1-29/29
Sequence Identity: 34% (10 aa)

MWQTILEKGDKNKDGKLSYQEFIDMLKQL
 .. . .. ||..||.....||.||.| |
EFKEMFRMFDKDGDGYIDFEEFKDMMKSL