Gene 7557 (Tetrahymena)

7557

Species: Tetrahymena
Alias: TTHERM_00676940, 1159, 102.m00077, n.7557, 7557, PreTt07557
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-A5

Sequence

Name Sequence Type Origin Length Description Download
7557.AA Protein None 671 None Fasta, JSON
7557.kin_dom Protein Kinase Domain None 47 None Fasta, JSON
7557.NA RNA None 1698 None Fasta, JSON

Protein domain

Protein domains of 7557.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 7557.AA Ciliate-A5 70-386 25 1.5e-72 247.38 In-house 39-275 (275) Show / Hide 
Range on Protein: 70-386
Range on HMM: 39-275/275
Sequence Identity: 25% (85 aa)

QRMNLKHRNILMLYYAHEANEDNICGDFNKITIYFEYYFHDLEKELNRRRENGLDQQIQISTQITNYPINVNFINSTAYKFLVKLLFFLSXXXXXXXXXX
|||.|.| ||. |.  |  ... .|..| |. .|.||. ..||.|...|. . .|                                             
QRMQLQHPNIVKLIDFHTHKKEEFCSQFYKVNCYYEYHDNNLEQEMQMRKQCQKD---------------------------------------------

XXXXXXXXXXXXXXXXXXXXXXXXPQTKYQMKPSKYKALKEIGLINKQNEFFSESELWYLLDSLIQACCYFEKNKIYHGDIRPTNILLTPEGQVKIADHG
                                                 .|..|.||||..|.||..|.|...|.|.||||||.||.||..||||..|..
-------------------------------------------------IFYNEQELWYIMDCLISVCMYLQQNNICHGDIRPQNICLTQDGQVKLMDMN

-------ILHADHSNYYKMLSRREK-CYLSPILVRSLGVGE----FKPFHDHWKSDVYSLGMTLLEAASLCPP-LCAYDFENYQISHP-ILEELLNQCRA
        .     . |..  ..|   ||||..   . ...      | |.. ||||..|||..|| ...    .  ||.|  ||     .. |..  . 
ESKDFFYQINWSSYKQYQHHMSTENKQYLSPMQWYQMMHRDEQNIQRPEHNWYKSDVFCLGMICLEMCTMRDCTQFYYDYETFQIQNNQLIKQLIQMKEK

KYSDFFVNVIRDMLLDDENTRPSFENLRALL
|||..|.|.|. ||  .|| ||.|. ....|
KYSEQFINFIKQMLQFEENKRPDFHQIYQYL
Kinase 7557.AA Ciliate-B2 204-318 26 1.2e-15 33.21 In-house 84-197 (197) Show / Hide 
Range on Protein: 204-318
Range on HMM: 84-197/197
Sequence Identity: 26% (31 aa)

KYKALKEIGLINKQNEFFSESELWYLLDSLIQACCYFEKNKIYHGDIRPTNILLTPEGQVKIADHGILHADHSNYYKMLSRREKCYLSPILVRSLGVGEF
..   .|. .|.|| . | .  |  .   || .   |  . | | ||.|.|||.. .|. .  | ||      |     .  .| | ||  .      . 
ECSLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGISSIKKDNQQIKIKGFTKKYASPEQMECDHN-QT

KPFHDHWKSDVYSLG
      ..||.||.|
FVTNIDFQSDIYSMG
Kinase 7557.AA Ciliate-E4 210-267 37 3.5e-15 47.38 In-house 93-150 (150) Show / Hide 
Range on Protein: 210-267
Range on HMM: 93-150/150
Sequence Identity: 37% (22 aa)

EIGLINKQNEFFSESELWYLLDSLIQACCYFEKNKIYHGDIRPTNILLTPEGQVKIAD
.| . ..|.  |.|||.| .. ..| |  |  .  |.|||..| ||...    |||||
HIKQHKQQGQHFDESEIWQIAFCCINAMYYLQQVNITHGDLKPSNIFFDQYFMVKIAD
Kinase 7557.AA TKL 235-386 17 2.1e-13 44.64 In-house 143-364 (364) Show / Hide 
Range on Protein: 235-386
Range on HMM: 143-364/364
Sequence Identity: 17% (39 aa)

QACCYFEKNK--------IYHGDIRPTNILLTPEGQ--------------VKIADHGILH-ADHSNYYKMLS------------------RR-EKCYLSP
....|   ..        | | |. . |||.   ..              .||.| |.    ..|.  .. .                  ..  .....|
RGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAP

ILVRSL---------GVGEFKPFHDHWKSDVYSLGMTLLEAASLCPPLCAYDFENYQISHPILEELLNQCRAKY------------------SDF---FV
 . |            . ..| |    |.|||| |. | | .. |.|   |...  ....| .|| . ..  |                   .|.   . 
EVLRGQMNYTEKVGIDE-FCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDP-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMK

NVIRDMLLDDENTRPSFENLRALL
. . |    | . ||||. .   |
KLMQDCWDHDPEKRPSFQEILKRL
Kinase 7557.AA Ciliate-E1 96-315 14 2.8e-11 33.4 In-house 67-202 (202) Show / Hide 
Range on Protein: 96-315
Range on HMM: 67-202/202
Sequence Identity: 14% (33 aa)

DFNKIT-IYFEYYFHDLEKELN---RRRENGLDQQIQISTQITNYPINVNFINSTAYKFLVKLLFFLSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
|.|.|. |.||.. . |...|.   |                                                                          
DQNYICIIIFECCCCSLKDYLQNHNR--------------------------------------------------------------------------

XXPQTKYQMKPSKYKALKEIGLINKQNEFFSESELWYLLDSLIQACCYFEKNKIYHGDIRPTNILLTPEGQVKIADHGILH--ADHSNYYKMLSRREKCY
                |. . ......  |.. .. ..   ||.. .... ..|.|.|| |.||| . .|. ...|.|| .    ..|...  .   ..|
----------------LEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYY

LSPILVRSLGVGEFKPFHDHWKSDVY
 .|  . .  . . |.  .. |||.|
YPPEQYNCPEQEHNKNQKINYKSDIY
Kinase 7557.AA Ciliate-E4 22-123 22 2.8e-09 27.55 In-house 1-102 (150) Show / Hide 
Range on Protein: 22-123
Range on HMM: 1-102/150
Sequence Identity: 22% (23 aa)

YDFQTEISDKRFGDVYVYKHKMEKRYIGKRGHMCNSAPEYQTYLRSCKQRMNLKHRNILMLYYAHEANEDNICGDFNKITIYFEYYFHDLEKELNRRREN
|     . |  .||. .  ||  |  |  .     .  . .  .    .|  |.| || |.|.     ||. |  . .. . .||   ||. ..  ..  
YRKIESVKDIHYGDIQIMEHKIQKQIIVMKIRKFQNETKARQQQQQFRRRQDLNHENIIMVYEYFHKKEDQFCSSIYRLYWFMEYLQKDLQQHIKQHKQQ

GL
|.
GQ
Kinase 7557.AA SLK 223-330 29 2.9e-09 27.27 In-house 96-201 (259) Show / Hide 
Range on Protein: 223-330
Range on HMM: 96-201/259
Sequence Identity: 29% (32 aa)

ESELWYLLDSLIQACCYFEKNKIYHGDIRPTNILLTPEGQVKIADHGILHADHSNYYKMLSRREKCY-LSPILVRSLGVGEFKPFHDHWKSDVYSLGMTL
|. . |.   ...|  .  .||. | |..  |||.| .|.|..|| |.    ...  |  .     | . | .|    . . .|.   .|.|..|||.||
EDQIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKD-QPY--DYKADIWSLGITL

LEAASLCPP
.| | . ||
IEMAQMEPP
Kinase 7557.AA Meta 244-270 59 3.7e-09 22.51 In-house 143-169 (287) Show / Hide 
Range on Protein: 244-270
Range on HMM: 143-169/287
Sequence Identity: 59% (16 aa)

KIYHGDIRPTNILLTPEGQVKIADHGI
|| | || | | ||. .|.||||| |.
KIIHRDIKPSNLLLNDDGHVKIADFGV
Kinase 7557.AA Ciliate-E2-Unclassified 209-270 28 9.2e-09 26.54 In-house 123-193 (352) Show / Hide 
Range on Protein: 209-270
Range on HMM: 123-193/352
Sequence Identity: 28% (20 aa)

KEIGLINKQNEFFSESELW-----YLLDSLIQACCYFEKNK-IYHGDIRPTNILLTPEG---QVKIADHGI
....  .||.. |.| .       ...  ..|. .|  ... | | || | |||.. .|   ..||.| ||
NDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGI
Kinase 7557.AA LKB 233-270 39 1.1e-08 21.93 In-house 113-150 (265) Show / Hide 
Range on Protein: 233-270
Range on HMM: 113-150/265
Sequence Identity: 39% (15 aa)

LIQACCYFEKNKIYHGDIRPTNILLTPEGQVKIADHGI
|...| |    .. | || | |.||| .. .|| | |.
LCDGCEYLHSQRVVHKDIKPGNLLLTHDNTLKICDFGV
Kinase 7557.AA STE 205-267 29 9.8e-07 19.95 In-house 128-190 (359) Show / Hide 
Range on Protein: 205-267
Range on HMM: 128-190/359
Sequence Identity: 29% (20 aa)

YKALKEIGLINKQN----EFFSESELWYLLDSLIQA-CCYFEKNKIYHGDIRPTNILLTPEGQVKIAD
.|  ...|  ...|     .|.||.. | . .....   | ....| | || | ||||     ||..|
IKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCD
Kinase 7557.AA S_TKc 198-390 15 1.1e-05 -93.7 SMART 1-231 (231) Show / Hide 
Range on Protein: 198-390
Range on HMM: 1-231/231
Sequence Identity: 15% (43 aa)

YQMK------------------PSKYKALKEI--------------------------------------G-------LINKQNEF-----FSESELWYL
|..                     .. |.|.|                                      |       .| |..       |.| . ...
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFY

LDSLIQACCYFEKNKIYHGDIRPTNILLTPEGQVKIADHGILHADHSNYYKMLSRREKC----YLSPILVRSLGVGEFKPFHDHWKSDVYSLGMTLLEAA
.  ...|  |  ...| | |. | ||||.   ..||.| |.              .  |    |..| ..           ... |.|..|.| .| | .
MYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL----------GYGKCKCDWWSCGCILYEML

SLCPPLCAYDFENYQISHPILEELLNQCRAKYSDFFVNVIRDMLLDDENTRPSFENLRA-----LLLPFQ
. .|| .    . ... . |.           |. . . || .|  | . ||.   . .      . |. 
CGYPPFP----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 7557.AA STE 311-382 24 0.000135 12.29 In-house 248-351 (359) Show / Hide 
Range on Protein: 311-382
Range on HMM: 248-351/359
Sequence Identity: 24% (25 aa)

KSDVYSLGMTLLEAASLCPPLCA-YDF-ENYQIS------------------HPILEELLNQC------------RAKYSDFFVNVIRDMLLDDENTRPS
|.|..||| |..| |  .||..  ...   ..|                   .| |.. | |               |.|. | . |.  |  | | ||.
KCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPT

FENL
 . |
ASQL
Kinase 7557.AA SLK 22-86 27 0.040404 2.81 In-house 1-65 (259) Show / Hide 
Range on Protein: 22-86
Range on HMM: 1-65/259
Sequence Identity: 27% (18 aa)

YDFQTEISDKRFGDVYVYKHKMEKRYIGKRGHMCNSAPEYQTYLRSCKQRMNLKHRNILMLYYAH
..   |. |  || ||  .|| .|..   .    ..  | . |.       ..|| ||. || |.
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAY