Gene 20533 (Tetrahymena)

20533

Species: Tetrahymena
Alias: 882, PreTt20533, 20533, TTHERM_00898280, 160.m00069
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: Ciliate-C1

Sequence

Name Sequence Type Origin Length Description Download
20533.AA Protein None 305 None Fasta, JSON
20533.kin_dom Protein Kinase Domain None 254 None Fasta, JSON
20533.NA RNA None 918 None Fasta, JSON

Protein domain

Protein domains of 20533.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 20533.AA Ciliate-C1 29-282 47 1.3e-240 633.61 In-house 1-328 (328) Show / Hide 
Range on Protein: 29-282
Range on HMM: 1-328/328
Sequence Identity: 47% (156 aa)

MEIMRTIGKGKTCTVKTAKMPNSDKVFAIKQFK--------------------SYAS--AVQDLNNEITSLQTLS-HENIIEMVS------FDKKN----
|.||.|||.|.||.|...||||..||.|.||||                    ...|  ..||.||||..||.|. |.||..||.      .||||    
MKIMKTIGHGYTCKVFYCKMPNNQKVYAVKQFKNEYTSQQQLTFKDSSSPRENTHHSESCMQDHNNEIKHLQELKNHPNIVNMVQIIREIQYDKKNGQTY

----VVFEYLSNGELFDVVAKKK--FSERVAKFYFRQLINAVQYIHENGFAHRDIKLENILISDEFNLKLADFGFA------------SKMTEGQKFER-
    .||||.|||||||..|.|.  |.|..|..||.||||..||||.|...|||.|.||||....||||.||||||            ||...|.|... 
CFMCIVFEYCSNGELFDYIAHKGPLFNEELARYYFHQLINVIQYIHQNNICHRDLKPENILLDENFNLKIADFGFAQFLNSASSQNTLSKQKDGEKMNHN

-------------------IMGTEGYMAPELQARQRYCGKKVDIFACGVVLFSIVNGMPPFFK-ATQSDPYYRFFVDNNFDAYWANLAKKY--NNNISDE
                   .|||||||||||...|||||.|||||||||.||..|.|.|||.| |..||||||||..|....||....|.|  .|..|.|
TSSTECSDASSDESHWLYVCMGTEGYMAPELHEKQRYCGSKVDIFACGVILFCMVHGHPPFHKIAHPSDPYYRFFCENRYHQYWQCHQKNYGQHNFFSNE

FKDLINRMLAYNEEDRISASEILNHPWL
|.||||.|||||...||...||..|||.
FMDLINQMLAYNPQKRITLQEIKCHPWY
Kinase 20533.AA CAMK 34-282 22 1e-90 292.46 In-house 1-425 (425) Show / Hide 
Range on Protein: 34-282
Range on HMM: 1-425/425
Sequence Identity: 22% (97 aa)

TIGKGKTCTVKTAKMPNSD------------KVFAIKQFKSY-----------------------------ASAVQDLNNEITSLQTLS-------HENI
|.|.|  ..|| ..  |.             . .|||  .                               ..  . . .||  ...|.       |.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IEMVS---------------FDKK---------NVVF---EYLSNGEL----FDVVAKK----------------KFSERVAKFYFRQLINAVQYIHENG
| .                 . .|           |.   || |.|||    || . ..                .|.|| |..||||.. ||.|.|...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

FAHRDIKLENILISDE-----------------FNLKLADFGFASKMTE------------------------GQKFERIMGTEGYMA-PELQAR-----
 .|||.|.||||..|                  .|.|..||||| |...                        |||..   || .||| ||.  .     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------QRYCGKKVDIFACGVVLFSIVNGMPPFFKATQSDPY---------YRFFVDNNFDAYW-ANLAKKY---------NNNISDE--------FK
        ..|.|.|.|. .|||.|.  . | |||   .... .         |. |       |.      .           ..||||         |
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DLINRMLAYNEEDRISASEILNHPWL
|||..|| .. |.|......|||||.
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 20533.AA S_TKc 29-282 30 1.2e-77 265.23 SMART 1-231 (231) Show / Hide 
Range on Protein: 29-282
Range on HMM: 1-231/231
Sequence Identity: 30% (83 aa)

MEIMRTIGKGKTCTVKTAKMPNSDKVFAIKQFKSYASAVQDLNNEITSLQTLSHENIIEMVSF---DKKNVVFEYLSN--GELFDVVAKKK-------FS
 ||.|.||||   .|. ..  ......|||. |      ... .||  |.   |.||. .  .   |.  .|.||...  |.|||.  |..       |.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

ERVAKFYFRQLINAVQYIHENGFAHRDIKLENILISDEFNLKLADFGFASKMTEGQKFERIMGTEGYMAPELQARQRYCGK-KVDIFACGVVLFSIVNGM
| .|.||..|...|..|.|..|. |||.| ||||...  ..|..|||.| ..        . ||  |||||.       || |.|. .||..|.  . | 
E-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGY

PPFFKATQSDPYYRFFVDNNFDAYWANLAKKYNNNISDEFKDLINRMLAYNEEDRISASEILN-------HPWL
|||    | .  ..  .                   |.|.||.|...| .. |.|..| |.|.       |||.
PPFP---QMQMMFKKIG-------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 20533.AA CAMKL 30-282 32 7.7e-77 244.72 In-house 2-297 (297) Show / Hide 
Range on Protein: 30-282
Range on HMM: 2-297/297
Sequence Identity: 32% (99 aa)

EIMRTIGKGKTCTVKTAKM-PNSDKVFAIKQFK--SYASAVQDLNN--------------EITSLQTLS---HENIIEMVSF----------DKKNVVFE
.| .|.|||   .|| |.   .  .  |||  .        . ..|              ||  .. |.   |.||| .             .| . | |
RIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVME

YLSNGE--LFDVVAKK-----KFSERVAKFYFRQLINAVQYIHENGFAHRDIKLENILISDEF--NLKLADFGFASKMTE-----GQKFERIMGTEGYMA
| |.||  ||| . |.     ...|. |..||||.. ||.|.|..| .|||||.||||...    |.|..||||. ....     |||..   |.  |||
YCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMA

PELQAR--QRYCGKKVDIFACGVVLFSIVNGMPPFFKAT--QSDPYYRFFVDNNFDAYWANLAKKYNNN----ISDEFKDLINRMLAYNEEDRISASEIL
||. ..  ..|.|.|||| .|||.|. .| |  ||  .|  .        .||.   || .    |. .    .| . .||| .||  | |.|... .|.
PEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNK------QGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIM

NHPWL
||||.
NHPWM
Kinase 20533.AA Pkinase 29-282 27 1.5e-75 262.09 Pfam 1-293 (293) Show / Hide 
Range on Protein: 29-282
Range on HMM: 1-293/293
Sequence Identity: 27% (82 aa)

MEIMRTIGKGKTCTVKTAKMPNSDKVFAIKQFKSYASAVQDLNN-----EITSLQTLSHENIIEMVSFD--KKNVV--FEYLSNG----ELFDVVA---K
 .| |.||.|   .|. ..  .. |..|.|..|      . . .     ||  .. |.|.||...  .   |...   .||. .|    .|||..    .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KKF--SERVAKFYFRQLINAVQYIHENGFAHRDIKLENILISDEFNL----KLADFGFASK--MTEGQKFERIMGTEGYMAPELQARQRYCGKKVDIFAC
..|  ||...|||..|.. ...|.|..|. |||.|.|||||... ..    |..|||.| .     .. .  . || .|||||.   ..| |.|||...|
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVVLFSIVNGMPPFFKA----TQSDPYYRFFVDNN--FDAYWANL-------------AKKYNNNISDEFKDLINRMLAYNEEDRISASEILNHPWL
|..|.  ..| |||  .    .  |...... .    ..  | ..             ...   |.|.|.||.|...|... ..|..| .||.|||.
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 20533.AA Ciliate-E2 29-282 21 1.1e-66 227.89 In-house 1-365 (365) Show / Hide 
Range on Protein: 29-282
Range on HMM: 1-365/365
Sequence Identity: 21% (83 aa)

MEIMRTIGKGKTC-----TV-KTAKMP-----------------NSDKVFAIKQF----KSYASAVQDLNNEIT----------SLQTLSHENIIEMV--
 .. . ||.|        .| |. |.                  .  | .|.|..    . . . ......||            |..|.| |||.|.  
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

----SFDKKNVVFEYLSNGELFDVVAKK------------KFSERVAKFYFRQLIN---------------AVQYIHENG-FAHRDIKLENILISDEFNL
    . ..   |.||.. |.|||   ..            .|.|. .|....|...               |..|.|...   |||||.||||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLADFGFAS----------------KMTEGQ-----------------KFERIMGTEGYMAPELQARQRY--------CGKKVDIFACGVVLFSIVNGMP
|..|||..                 .... .                  | .| || ||||||   .. |         ..|.||...||.|.  . | |
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFFKATQSDPYYRFFVDNNFDAYWANLAKKYN------------------------NNISDEFKDLINR----MLAYNEEDRIS-ASEILNHPWL
||                        . .. .                        ...|.| ||||..    || ...| ||. ...||||||.
PF------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 20533.AA ULK 29-282 25 6.3e-60 205.41 In-house 1-329 (329) Show / Hide 
Range on Protein: 29-282
Range on HMM: 1-329/329
Sequence Identity: 25% (84 aa)

MEIMRTIGKGKTCTVKTAK-MPNS---DKVFAIKQ-FKSYASAVQD----------LNNEITSLQTLS--------HENIIEMVSF--DKKN----VVFE
 .. . .|||   .|  .. . .    ....|.|.  |.. .  ..          |.|||  ...|         |.||...  .  ....     ..|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

YLSNGELFDVVAKKK-----------FSERVAKFYFRQLINAVQYIHENGFAHRDIKLENILISDEFN------------LKLADFGFASKMTEG----Q
|   | |..   |.|           .||  |. .|.|..|. ...|...  |||||..||||.. .             ||.|||||| .....    |
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

KFERIM------GTEGYMAPELQA----RQRYCGKKVDIFACGVVLFSIVNGMPPFFKATQSDPYYRFFVDNNFDAYWAN-----LAKKYN-----NNIS
 .          ||  ||||..      .. |. .|.||.  |.... .. | |||..   .| | ..  ..  . .  .        ...     ..||
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQIS

DEFKDLINRMLAYNEEDRISASEILNHPWL
.|.|||| ||| |.|.||||  |..||||.
PECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 20533.AA ULK 29-282 24 7.6e-58 198.5 In-house 1-324 (324) Show / Hide 
Range on Protein: 29-282
Range on HMM: 1-324/324
Sequence Identity: 24% (83 aa)

MEIMRTIGKGKTC-TVKTAK-MPNS--DKVFAIKQFK---SYASAVQ--------DLNNEITSLQTLS---HEN--IIEMVSF--DKKN----VVFEYLS
 .. . .|||    .|  .. . .   ....|.|.        .  .         |.|||  ...|    |.|  |...  .  .. .     ..||  
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

NGELFDVVAKKK----------FSERVAKFYFRQLINAVQYIHENGFAHRDIKLENILISDEFN------------LKLADFGFASKMTEGQKFERIM--
 | |..   |.|          .||  |. .|.|..|. ...|...  |||||..||||.. .             ||.|||||| .  .... . ..  
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQT

--------GTEGYMAPELQA----RQRYCGKKVDIFACGVVLFSIVNGMPPFFKATQSDPY------------YRFFVDNNFDAYW---ANLAKK---YN
        ||  ||||...     .. |. .|.||.  |.... .. | .|||.   .| |            .          .     .. ..   ..
CVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQ---------QIYIKNQPIQFPKPPKD

NNISDEFKDLINRMLAYNEEDRISASEILNHPWL
..||.|.|||| ||| |.|.||||  ||.||||.
PKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 20533.AA Ciliate-E2-Unclassified 30-282 23 5.1e-57 195.74 In-house 2-352 (352) Show / Hide 
Range on Protein: 30-282
Range on HMM: 2-352/352
Sequence Identity: 23% (82 aa)

EIMRTIGKGKTCTVKTAKMPNSDKVFA-----IKQFKSYA-----SAVQDLNNEITSLQTLS-------------------HENIIEMVSFDKKN----V
.| ..||.|  ..|. ..  ...| ..     .|....|.     .   ...||.. .. ..                   |..|. |.  ...      
KIIKQIGQGGFGKVYKCQH-KKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYI

VFEYLSNGELFDVVAK------------------KKFSERVAK-----FYFRQLINAVQYIHENG-FAHRDIKLENILISDE---FNLKLADFGFAS---
| ||. .|.|..   |                  |.|.|. ||     |||.|.... .|.|... . |||||.||||....   ...|..|||...   
VMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQ

-----KMTEG---------QKFERIMGTEGYM----APELQARQRYCG---KKVDIFACGVVLFSIVNGMPPFFKATQSD---------------PYYRF
     . |..         |..  ..|| .||    |||.  .| | .   .|.||...||.|. .. | .||.  .. .                .|. 
QNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

FVDNNFDAYWANLAKKYNNNISDEFKDLIN----RMLAYNEEDRISASEILNHPWL
. ..|..  ...  .    ..|.| ||.||    .|| .| . ||....||||||.
IKQKNIQFPKFPWQQ-IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 20533.AA MARK 30-218 35 2.8e-54 175.91 In-house 2-206 (262) Show / Hide 
Range on Protein: 30-218
Range on HMM: 2-206/262
Sequence Identity: 35% (73 aa)

EIMRTIGKGKTCTVKTAKMPNSDKVFAIKQFK---SYA-SAVQDLNNEITSLQTLSHENIIEM-VSFD----KK--NVVFEYLSNGELFDVVAKK---KF
.. .|||.|  ..|| |   .... .|||  .        . . .  ||  .. |.|.|||..   ..    ..  ... || |.|||.| . ..   . 
KMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRL

SERVAKFYFRQLINAVQYIHENGFAHRDIKLENILISDEF--NLKLADFGFASKMTEGQKFERIMGTEGYMAPELQARQRYCGKKVDIFACGVVLFSIVN
.|. |. .|||.. ||.| |... .|||||.||||| ..   | |..||||. . ..||| ..  ||  |||||.  ...|.|.|||| ..||||. .| 
HEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVC

GMPPF
|  ||
GYFPF
Kinase 20533.AA STE 29-282 19 1.5e-48 167.59 In-house 1-359 (359) Show / Hide 
Range on Protein: 29-282
Range on HMM: 1-359/359
Sequence Identity: 19% (74 aa)

MEIMRTIGKGKTCTVKTAKMPN---------------SDKVFAIKQFK------------------SYASAVQDLNNEITSLQTLS--HENIIEMVSF--
 |... |||| . || .|.  .               . ...|||| .                  .  . .|.. .||  .. ..  |.||..      
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

---------DKKNVVFEYLSNGELFDVVA---KKKFS------------ERVAKFYFRQLINA-VQYIHENGFAHRDIKLENILISDEFNLKLADFGFAS
         |. ... ||...| | |..    .....            | . ... ||.. .  .|.|...  |||||  |||.      ||.|||...
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

KMTE-----------------GQKFERIMGTEGYMAPELQAR-----QRYCGKKVDIFACGVVLFSIVNGMPPFFKATQS--------------------
..|.                 .||   . ||  .||||   .        .. |.||   | ..   ..| ||... .                      
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---DPYYRFFVD-------------NNFDAYWANLAKKYNNNISDEFKDLINRMLAYNEEDRISASEILN--HPWL
   .|  ..  .                          |  . |.|||| ||. | .. ..| .||. |.  ||..
IVNGPPPPLPDHLSQNEMISYGGSGT-T----------YPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 20533.AA Ciliate-E2a 30-218 30 1.1e-43 126.48 In-house 2-216 (275) Show / Hide 
Range on Protein: 30-218
Range on HMM: 2-216/275
Sequence Identity: 30% (66 aa)

EIMRTIGKGKTCTVKTAKMPNSDKVFAIKQFKSYASAVQD-----LNNEITSLQTLSHENIIEMVSF--DKKNV--VFEYLSNGELFDVVAKKK-FSER-
.. . ||||.   |. |.  .  | ||.| |.  . ..|.     . |||  ...|.| ||| .  .  |..|   |.||.. |||.|   ..| | |  
KFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEI

-VAKFYFRQLI-NAVQYIHENGFAHRDIKLENILIS---DE----FNLKLADFGFASKM--TEGQKFERIMGTEGYMAPELQARQRY-----CGKKVDIF
 ... . .||.  ...|.| ..  |||.|.||||.     .    ...|..|||.| .    |...   . || ||.|||...         ...|.|..
QEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYDTKCDMW

ACGVVLFSIVNGMPPF
 |||...  . | |||
SCGVIFYILLCGKPPF
Kinase 20533.AA Ciliate-E2a 249-282 44 3.9e-13 35.02 In-house 242-275 (275) Show / Hide 
Range on Protein: 249-282
Range on HMM: 242-275/275
Sequence Identity: 44% (15 aa)

NNISDEFKDLINRMLAYNEEDRISASEILNHPWL
...|.| |||. .|| .. . ||.| ..||||| 
EKCSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase 20533.AA MARK 250-282 42 1e-12 38.07 In-house 230-262 (262) Show / Hide 
Range on Protein: 250-282
Range on HMM: 230-262/262
Sequence Identity: 42% (14 aa)

NISDEFKDLINRMLAYNEEDRISASEILNHPWL
..|.| ..||.|.|  | |.|....||..|||.
HVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 20533.AA TyrKc 29-282 19 7.8e-12 -31.36 SMART 1-280 (280) Show / Hide 
Range on Protein: 29-282
Range on HMM: 1-280/280
Sequence Identity: 19% (56 aa)

MEIMRTIGKGKTCTVKTAKMPNSDKVFAIKQFKSYASAVQDLNNEITSLQTL--SHENIIEMVSFDKKN-----------VVFEYLSNGELFDVVAKKK-
 .  ...| |  ..|  ...       |.|  |..|  ..|. .|.  .  |  .|.||. ..    .            .|.|| ..| | |   |.. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-FSERVAKFYFRQLINAVQYIHENGFAHRDIKLENILISDEFNLKLADFGFASKMTEG----QKFERIM-----GTEG-----YMAPELQARQRYCGKKV
 .. .    .  |  .  .|.|.... |||.   |.|.....  | .||| . . ...       . ..     |. .      ||||   . . .  | 
KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKS

DIFACGVVLFSIV-NGMPPFFK-AT--QSDPYYRFFVDNNFDAYWANLAKKYNNN-------ISDEFKDLINRMLAYNEEDRISASEILNHPWL
|... ||... |  .|..|    .    |.   . .|..       .  ..  |.        .||  ... .  ... ||| . |||  |  .
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQG------YRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF