Gene 4107 (Tetrahymena)

4107

Species: Tetrahymena
Alias: 80.m00153, 690, 3675.m00051, PreTt04107, TTHERM_00585000, 4107
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: CAMK
Family: Ciliate-C1

Sequence

Name Sequence Type Origin Length Description Download
4107.AA Protein None 318 None Fasta, JSON
4107.kin_dom Protein Kinase Domain None 279 None Fasta, JSON
4107.NA RNA None 957 None Fasta, JSON

Protein domain

Protein domains of 4107.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 4107.AA Ciliate-C1 12-290 51 2.1e-268 707.3 In-house 1-328 (328) Show / Hide 
Range on Protein: 12-290
Range on HMM: 1-328/328
Sequence Identity: 51% (168 aa)

LKIYKKIGHGKTAEVFLVKDVMNN-SYALKKFRNEYTSQQQLTFKDSSSPRENSYHSTSCFSDPENEVKVLSELGNHPNITRIHF------FDGQH----
.||.|.||||.|..||..|...|. .||.|.|.||||||||||||||||||||..||.||..|..||.|.|.||.|||||.....      .|...    
MKIMKTIGHGYTCKVFYCKMPNNQKVYAVKQFKNEYTSQQQLTFKDSSSPRENTHHSESCMQDHNNEIKHLQELKNHPNIVNMVQIIREIQYDKKNGQTY

----ILMDLNRNGELFDYISLGSPLFDEELARFYFRQMVDVIDFMQQSSYAHRDIKPENILLDEHFNLKLSDFGFS------------TKQQEGEQLTH-
    |......||||||||....|||.|||||.||.|...||....|....|||.|||||||||.||||..||||.            .||..||...| 
CFMCIVFEYCSNGELFDYIAHKGPLFNEELARYYFHQLINVIQYIHQNNICHRDLKPENILLDENFNLKIADFGFAQFLNSASSQNTLSKQKDGEKMNHN

-------------------ILGTDGYMAPELLRGRGYDGFKVDIFAMGVVLFCMVNGFPPYYKKAIATDPYYRFFVEKRTHVYWSCLQRKY--NKNYSNE
                   ..||.|||||||.....|.|.||||||.||.|||||.|.||..|.|...|||||||.|.|.|.||.|.|..|  ....|||
TSSTECSDASSDESHWLYVCMGTEGYMAPELHEKQRYCGSKVDIFACGVILFCMVHGHPPFHKIAHPSDPYYRFFCENRYHQYWQCHQKNYGQHNFFSNE

FMSLVTGMLAYNPQERIDLQMIKSHPWY
||.|...|||||||.||.||.||.||||
FMDLINQMLAYNPQKRITLQEIKCHPWY
Kinase 4107.AA CAMK 17-290 19 6.7e-77 247.15 In-house 1-425 (425) Show / Hide 
Range on Protein: 17-290
Range on HMM: 1-425/425
Sequence Identity: 19% (83 aa)

KIGHGKTAEVFLVKDVMNNS-------------YALKKFRNE-YTSQQQLTFKDSSSPRENSYHS-----------------TSCFSDPENEVKVLSELG
..|.|  ..|.|...  ..              .| |    .  ...|.  .. |         .                  .     ..|..... | 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQN-QDY-S---------NCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQ

------NHPNITRIHFFDG-----------------------QHILM---DLNRNGEL----FDYISLGSPL--------------FDEELARFYFRQMV
      .|||| ... .                          .. |   ..  .|||    ||||   ..               |.|. ||.||||..
GIGNKLDHPNIIKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQIC

DVIDFMQQSSYAHRDIKPENILLDEH-----------------FNLKLSDFGFSTKQQE------------------------GEQLTHILGTDGYMA-P
. .... .   .|||.||||||||..                 .|.|..||||..| ..                        |. ..   || .||| |
SAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAP

ELLRG-------------RGYDGFKVDIFAMGVVLFCMVNGFPPYYKKAIATDP--------YYRFFVEKRTHVYW-SCLQRKY---------NKNYSNE
|.|.|             . |.|.|.|. ..||.|. |. |.||.| .    ..        .|. |   ..  |.    . .           .. |.|
EVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDE

--------FMSLVTGMLAYNPQERIDLQMIKSHPWY
         ..|. .|| ..|..|. .. ...|||.
FHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 4107.AA S_TKc 12-290 24 2.5e-66 227.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 12-290
Range on HMM: 1-231/231
Sequence Identity: 24% (72 aa)

LKIYKKIGHGKTAEVFLVKDVM-NNSYALKKFRNEYTSQQQLTFKDSSSPRENSYHSTSCFSDPENEVKVLSELGNHPNITRIHFF---DGQHILMDLNR
 .| .|||.|  ..|......  .  .|.|. .                             . ..|...|..  .|||| ... .   |  .. |..  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------------------------EHIRREIQILKK--HHPNIVKLYDVFQDDHLYMVMEYCD

N--GELFDYISLGSPL-----FDEELARFYFRQMVDVIDFMQQSSYAHRDIKPENILLDEHFNLKLSDFGFSTKQQEGEQLTHILGTDGYMAPELLRGRG
.  |.|||||    .      |.|  ||||..|... .... .    |||.|||||||||  ..|..|||....       |.. ||  |||||.|   |
GDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---G

YDGFKVDIFAMGVVLFCMVNGFPPYYKKAIATDPYYRFFVEKRTHVYWSCLQRKYNKNYSNEFMSLVTGMLAYNPQERIDLQMIKS-------HPWY
|...|.|. . |..|. |. | ||..      .  ..  .                   | |. ... ..| ..|..|.    .         ||| 
YGKCKCDWWSCGCILYEMLCGYPPFP----QMQMMFKKIG-------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 4107.AA Pkinase 12-290 24 2.9e-64 224.59 Pfam 1-293 (293) Show / Hide 
Range on Protein: 12-290
Range on HMM: 1-293/293
Sequence Identity: 24% (80 aa)

LKIYKKIGHGKTAEVFLVKDVMNNS-YALKKFRNEYTSQQQ------LTFKDSSSPRENSYHSTSCFSDPENEVKVLSELGNHPNITR-IHFF-DGQHIL
..| .||| |  ..|.. ... ..  .|.|... . .. ..      |                       .|.... .| ||||| | ...| |..|| 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-----------------------SEIQIMKRL-NHPNIVRLYDWFEDKDHIY

--MDLNRNG----ELFDYIS--LGSPL-FDEELARFYFRQMVDVIDFMQQSSYAHRDIKPENILLDEHFNL----KLSDFGFSTK--QQEGEQLTHILGT
  |.. ..|    .||||||   . .. |.|. ..||..|..  .... . .  |||.||||||.|.. ..    |..|||.. .     .. .|.. ||
MVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGT

DGYMAPELLRGRGYDGFKVDIFAMGVVLFCMVNGFPPYYKKA----IATDPYYRFFVEKRTHVYWSCLQR---------------KYNKNYSNEFMSLVT
 .|||||..||. |.| |||....|..|..|..| ||..  .       |......  ... . ... .                .  .| | |. ....
PWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIK

GMLAYNPQERIDLQMIKSHPWY
..|...|..|.  . |. ||| 
WCLCKDPKKRPTAEQILQHPWF
Kinase 4107.AA AGC 12-290 18 3.4e-56 142.74 In-house 1-395 (395) Show / Hide 
Range on Protein: 12-290
Range on HMM: 1-395/395
Sequence Identity: 18% (79 aa)

LKIYKKIGHGKTAEVFLVKDV-------MNNSYALKKFRNEY---------TSQQQLTFKDSSSPRENSYHSTSCFSDPE-----NEVKVLSELGN----
 ...| || |   .|.||...        .  ||.|. . ..           . .  .   .                .     .| ..|... .    
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHW-KQ----------------DQGYVWEERNILEKCNHTHNH

-----HPNITR-I--HFFDGQH----ILMDLNR---------NG-ELFDYISL--GSPLFDEELARFYFRQ-------MVDVIDFMQQ-SSYAHRD-IKP
     ||.|..     | | .|    ..|..            | ||| ..    ..  |||| ||||. .       .|  .... .   . ||| .||
PIKSHHPFIVKILHYSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKP

ENILLDEHFNLKLSDFGFSTK---------------------------------------QQEG-----------EQLTH-ILG--TDGYMAPELLRGRG
|||||||. ..||.|||....                                       |...           ...|. . |  |  ||||| |    
ENILLDEDGHIKLTDFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----

YDGFKVDIFA--MGVVLFCMVNGFPPYYKKAIATDPYYRFFVEKRTHVYWSCL--------QRKYN----------KNYSNEFMSLVTGMLAYNPQERID
  |. .|. .  .|.... |. | ||.| .   . .  .  .. .  .. . .        . |..          .. |.| ..|....|  .| .|. 
-YGKACDWWSFGLGCLMYEMLTGYPPFYGDNPQE-N-RH-PFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLG

----------LQMIKSHPWY
           . ||.||| 
CGGNDFGDKGAEEIKNHPWF
Kinase 4107.AA Ciliate-E2 12-290 20 6.4e-52 176.5 In-house 1-365 (365) Show / Hide 
Range on Protein: 12-290
Range on HMM: 1-365/365
Sequence Identity: 20% (84 aa)

LKIYKKIGHGKTAEVFLVKD------------------------VMNNSYALKKFRN---EYTSQQQLTFK----DSSSPRENSYHSTSCFSDPENEVKV
 |. |||| |  . |...|.                        | .. ||.| ...   |...| .  ..    .                      | 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCF--------------------Y-KK

LSE------LGNHPNITRIH-FFD--GQ---HILMDLNRNGELFDYI------------SLGSPLFDEELARFYFRQMVD---------------VIDFM
. .      . ||||| ... .|    .    . |..   |.|||||            . .   |.|. ......| ..                . ..
I-NEKNILEQLNHPNIIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYL

QQSS-YAHRDIKPENILLDEHFNLKLSDFGFSTKQQEG--------------------------------EQLTHILGTDGYMAPELLRGRGYDG-----
 .     ||||||||||.     .|..|||.|.|...                                 ..   |.|| |||||| |.| .||.     
HSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQK

---FKVDIFAMGVVLFCMVNGFPPYYKKAIATDPYYRFFVEKRTHVYWSCLQRKYN------------------------KNYSNEFMSLVTG----MLA
   .|.||...||.|..|. | ||.                         .| . .                        |. |.| . |       || 
GYDYKCDIWSLGVILYEMLFGKPPF-------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQ

YNPQERID-LQMIKSHPWY
..|..||.  . |. ||| 
KDPEKRITGWEQILNHPWF
Kinase 4107.AA Ciliate-E2-Unclassified 13-290 22 1.2e-50 173.87 In-house 2-352 (352) Show / Hide 
Range on Protein: 13-290
Range on HMM: 2-352/352
Sequence Identity: 22% (84 aa)

KIYKKIGHGKTAEVFLVKDVMNNSYA-----LKKFRNEY----------------TSQQQLTFKDSSSPRENSYHSTSCFSDPENEVKVLS-ELGNHPNI
|| |.||.|  ..|.....  .. ..     .||...                    ...  . .. .                .  | .  .| |||..
KIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKK-YHQR-K----------------Y-NKIMQQILLNHPHP

TRIHFFDGQH------ILMDLNRNGELFDYISLGSP----------------LFDEELAR-----FYFRQMVDVIDFMQQSS-YAHRDIKPENILLDEH-
 ....|.         | |.. ..|.|..||.  .                  |.|. |.     |||.| .. .... ..    ||||||||||.|.  
FIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNG

--FNLKLSDFGFSTKQQEGEQ----------------LTHILGTDGYM----APELLRGRGYDG---FKVDIFAMGVVLFCMVNGFPPYY--KKAI----
  ...|..|||.| |.|. ..                .... || .||    |||.|.| .||.   .|.||...||.|..|. | .|.|  .. .    
KNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQL

-------ATDPYYRFFVEKRTHVYWSCLQRKYN----------KNYSNEFMSLVT----GMLAYNPQERIDLQMIKSHPWY
       |           |  .|  ..|....          |. |.|   ...     || .|| .||... |. ||| 
ITQWINNA----------YRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 4107.AA CAMKL 12-224 29 1.1e-49 156.67 In-house 1-235 (297) Show / Hide 
Range on Protein: 12-224
Range on HMM: 1-235/297
Sequence Identity: 29% (74 aa)

LKIYKKIGHGKTAEVFLVKD-VM-NNSYALKKFR------NEYTSQQQLTFKDSSSPRENSYHSTSCFSDPEN--------EVKVLSELG--NHPNITRI
 .| | .|.|  ..| | ..    .  .| |         ......  .                     ...        |.. .. |    |||| ..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCG--------------------QKHESDMRIRREIQIMKMLNIGKHPNIIKL

HFF----------DGQHILMDLNRNGE--LFDYIS-LGSPL--FDEELARFYFRQMVDVIDFMQQSSYAHRDIKPENILLDEHF--NLKLSDFGFSTKQQ
.            .  .. | .  .||  |||||   | .   ..|. ||.||||.|. .... .   .|||||||||||||.   |.|..|||||....
YEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYR

E-----GEQLTHILGTDGYMAPELLRG--RGYDGFKVDIFAMGVVLFCMVNGFPP
.     |. |.   |.  |||||.. |  . |||.|||| ..||.|. || |  |
PCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLP
Kinase 4107.AA Ciliate-E9 101-290 34 4.5e-44 138.66 In-house 87-298 (298) Show / Hide 
Range on Protein: 101-290
Range on HMM: 87-298/298
Sequence Identity: 34% (75 aa)

ILMDLNRNGELFDYISLGSPLFDEELARFYFRQMVDVIDFMQQSS-YAHRDIKPENILLDEHFNLKLSDFGFSTKQQEGEQLTHIL-----------GTD
| |    ||.||| ||     |.|..|..||.|..| |..|.|     |||.||||.|.|. .|.|. |||.|   |.  ..| .            || 
IVMEYANNGCLFDLISMHTEKFNENVAKYYFKQLIDSIEYMHQYQNICHRDLKPENMLIDKNYNMKICDFGMSA--QCRNDKTQVIGNLQCQPKENHGTN

GYMAP----ELLRGRGYDGFKVDIFAMGVVLFCMVNGFPPYYKKAIATD-------PYYR---FFVEKRTHVYWSCLQRKYNKNY-SNEFMSLVTGMLAY
 |  |    .   | .| | |.|||  |..|| || .  |.       |        |||   |. . .   .|   | .||    ..||. .   ||  
QYNPPNNQQQQYQGIKYNGQKFDIFSAGCILFMMVMNQYPFFHTNCYNDTTIDKIWQYYRIFFFCMDNCQN-FWD--QFIYNYRPEEQEFIDMMNWMLQQ

NPQERIDLQMIKSHPWY
 || || .| |..||| 
DPQNRISIQEIRMHPWM
Kinase 4107.AA MARK 77-221 41 1.4e-42 137.07 In-house 49-202 (262) Show / Hide 
Range on Protein: 77-221
Range on HMM: 49-202/262
Sequence Identity: 41% (64 aa)

EVKVLSELGNHPNITRIHF-FD----GQ--HILMDLNRNGELFDYISLG--SPLFDEELARFYFRQMVDVIDFMQQSSYAHRDIKPENILLDEHF--NLK
|..... | .||||.. .  ..    ..  .. |..  .|||.|||      .|  ||.|| .|||.|  . .. . . .||||||||||.||.   | |
EIEIMKKL-DHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGRL-HEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIK

LSDFGFSTKQQEGEQLTHILGTDGYMAPELLRGRGYDGFKVDIFAMGVVLFCMVNG
..|||||.. ..|. |.   ||  |||||.. .. |||.|||| ..||||. || |
IIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCG
Kinase 4107.AA TSSK 86-221 36 1.9e-37 120.46 In-house 74-225 (289) Show / Hide 
Range on Protein: 86-221
Range on HMM: 74-225/289
Sequence Identity: 36% (56 aa)

NHPNITRIH-FFDGQH----ILMDLNRNGELFDYISLGS-----PLFDEELARFYFRQMVDVIDFMQQSSYAHRDIKPENILLDEHFNLKLSDFGFSTKQ
.|||| ... .|. ..    . | . ..| |..||   .     .  .||.||. |||||. .....    .|||.| ||||||.|.|.||.||||. ..
KHPNIIQFYEMFETCQGKIYMVMEYAEHGDLLEYIQRRTQERCCGALHEEQARKWFRQMVSAVKYCHSHNVVHRDLKCENILLDKHWNIKLTDFGFARYW

QEGE--QLTHILGT----DGYMAPELLRGRGYDGFKVDIFAMGVVLFCMVNG
 ...  . .| ..|      | ||| |||. ||....|. .|||.|. ||.|
PRDDPGRCCHLSKTFCGSYAYAAPEILRGIPYDPKWYDVWSMGVILYIMVCG
Kinase 4107.AA QIK 101-221 37 1.9e-31 110.77 In-house 75-214 (272) Show / Hide 
Range on Protein: 101-221
Range on HMM: 75-214/272
Sequence Identity: 37% (53 aa)

ILMDLNRNGELFDYISL-GS-------------------PLFDEELARFYFRQMVDVIDFMQQSSYAHRDIKPENILLDEHFNLKLSDFGFSTKQQEGEQ
|...   |||.|||.   |                    |.  |. ||. | |..  ...  .   .|||.| ||||||.  | |. |||||  ...|. 
IVTEYCSNGEMFDYLCKHGRKGVKMVNSPDIGDQVLMGVPM-AENEARRWFWQICSAVHYCHKRNIVHRDLKAENILLDNNMNIKIADFGFSNWFKQGQL

LTHILGTDGYMAPELLRGRGYDGFKVDIFAMGVVLFCMVNG
|    |.  | |||.. |. ||| ||||  |||||. .| |
LMTWCGSPPYAAPEMFEGKEYDGPKVDIWSMGVVLYVLVCG
Kinase 4107.AA CAMKL 260-290 35 1.3e-09 26.66 In-house 268-297 (297) Show / Hide 
Range on Protein: 260-290
Range on HMM: 268-297/297
Sequence Identity: 35% (11 aa)

SNEFMSLVTGMLAYNPQERIDLQMIKSHPWY
| .  .|  .||  || .|. .. |..|||.
S-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
Kinase 4107.AA TyrKc 12-290 17 2.9e-08 -89.02 SMART 1-280 (280) Show / Hide 
Range on Protein: 12-290
Range on HMM: 1-280/280
Sequence Identity: 17% (59 aa)

LKIYKKIGHGKTAEVFLVKDVMNNSYALKKFRNEYTSQQQLTFKDSSSPRENSYHSTSCFSDPENEVKVLSELG-NHPNITRIH----FF-------DGQ
..  ||.|.|   ||.. .       | |. ...                           |  .| .....|| .|||| |..             .  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA------------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPL

HILMDLNRNGELFDYISLGSPLFDEELARFYFRQMVDVIDFMQQSS----------YAHRDIKPENILLDEHFNLKLSDFGFSTKQQEG------EQLTH
 |.| .  .| | ||.    |            .| | ..|. | .          . |||.   |.|..| .  | |||| | .  ..      ..  .
MIVMEYMPHGDLKDYLRKHRPK----------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYR

IL---GTDG-----YMAPELLRGRGYDGFKVDIFAMGVVLFCMV-NGFPPYYK---KAIATDPYYRFFVEKRTHVYWSCLQRKYNKNY---------SNE
     |...      |||| .. . .  .| |... ||... .  .| .||.    .   ..   . .|...         |     .         . |
KKEHKGGKTMLPIRWMAPECINYGKFT-TKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQG--------YRMPQPPNDYPMSFVCCPDE

FMSLVTGMLAYNPQERIDLQMIKSHPWY
  .. .   ...| .|   . |  |   
MYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 4107.AA TSSK 252-290 25 4e-06 15.91 In-house 251-289 (289) Show / Hide 
Range on Protein: 252-290
Range on HMM: 251-289/289
Sequence Identity: 25% (10 aa)

QRKYNKNYSNEFMSLVTGMLAYNPQERIDLQMIKSHPWY
... ... | |. .|.  ||. .| .|.... |..|.|.
PKPHSCWISQECKDLIRHMLQPHPCNRPHINEICHHCWM
Kinase 4107.AA MARK 270-290 42 0.000864 8.46 In-house 242-262 (262) Show / Hide 
Range on Protein: 270-290
Range on HMM: 242-262/262
Sequence Identity: 42% (9 aa)

MLAYNPQERIDLQMIKSHPWY
.|  || ||.... | .||| 
LLTVNPEERPTIEEIMKHPWM
Kinase 4107.AA QIK 260-290 29 0.001697 9.89 In-house 242-272 (272) Show / Hide 
Range on Protein: 260-290
Range on HMM: 242-272/272
Sequence Identity: 29% (9 aa)

SNEFMSLVTGMLAYNPQERIDLQMIKSHPWY
| .  .|.  ||  .|. |.  . |. |.| 
SQDCEHLIRHMLVVDPEHRYTIMQICQHRWM
Kinase 4107.AA MARK 13-32 45 0.029402 3.38 In-house 2-21 (262) Show / Hide 
Range on Protein: 13-32
Range on HMM: 2-21/262
Sequence Identity: 45% (9 aa)

KIYKKIGHGKTAEVFLVKDV
|. | ||||  |.| |. ..
KMLKTIGHGSYAKVKLACHK