Gene 1168 (Tetrahymena)

1168

Species: Tetrahymena
Alias: TTHERM_00852690, 3834.m00335, 1168, 99, PreTt01168, 150.m00060
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-D1

Sequence

Name Sequence Type Origin Length Description Download
1168.AA Protein None 340 None Fasta, JSON
1168.kin_dom Protein Kinase Domain None 270 None Fasta, JSON
1168.NA RNA None 1023 None Fasta, JSON

Protein domain

Protein domains of 1168.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc 1168.AA S_TKc 28-305 23 1.3e-62 215.2 SMART 1-231 (231) Show / Hide 
Range on Protein: 28-305
Range on HMM: 1-231/231
Sequence Identity: 23% (68 aa)

IEKSRPLGQGGFGTVYKGKYGN--QDVAVKELKQYIDNMGTVNEYYQQEIETSKQIMSIDCEYIVRVLGVVPTQYQCYVVMDLCIS---DLQKLRKESPN
 |. |..|.|.||.|||..  .  . ||.|..|          |  ..||.  |.    ....||. ..|  .    |.||..|     || .. |. . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK----HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

QR----LDVMTALKCIKEICLGIKSLHMKNITHRDIKPDNIFIGKNQQDQLICKVGDFGLGKNEQNMISKVGTISYMAPDMLDFSNQKYTN-KVDIWAIG
..    ..  .| . ...||.... .| ..| |||.||.||.. .        |..|||| .      . .||  |||| .|     .|.  |.|.|..|
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL---TTFCGTPWYMAPEVL-----GYGKCKCDWWSCG

VMAHELLTGTILFQGQTIDIIRNNILKSRNYKDWYKLSSSVAQTDFITQSFKHIQSESVINLIDMMLQKNPNDRKDINQIIT-----EVEQCM
..  |.|.|  .|.  ... . ..|.                             |......|. .|||.|..|  . .. .        . .
CILYEMLCGYPPFP--QMQMMFKKIG-----------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 1168.AA Ciliate-B1 28-235 35 2.7e-55 190.01 In-house 1-236 (290) Show / Hide 
Range on Protein: 28-235
Range on HMM: 1-236/290
Sequence Identity: 35% (85 aa)

IEKSRPLGQGGFGTVYKG-----KYGNQDVAVKEL-KQYIDNMGTVNEYYQQEIETSKQIMSID-----------CEYIVRVLGVVPTQYQCYVVMDLC-
. . . .|||... |..|     .. .| |||| . || .||    | |||||.|..... ..            |..|.. . |  .| | |..| .| 
YQQNNVIGQGAISQVFYGQFCQNQQCQQEVAVKKITKQTQDNDKQQNKYYQQELEIIQCLIKKMNNNKISCQSSPCDHICNIYDVIQCQQQYYIIMEYCE

ISDL-QKLRKESPNQRLDVMTALKCIKEICLGIKSLHMKNITHRDIKPDNIFIGKN--------QQDQLICKVGDFGLGKNEQN--MISKVGTISYMAPD
 .|| . . ....|  .|.  .|  ...|  ||. ||  .|.|||.||.||.| |         ||...| |..|||..|..|.  | |.|||| |||| 
QGDLYNYIYNCHQNFTHDI--VLDFCIQIAKGIQYLHKHKICHRDLKPENILIHKKNVPIYYNKQQNHYIFKITDFGISKMQQEYMMQSCVGTINYMAPE

MLDFSNQKYTNKVDIWAIGVMAHELLTGTILFQ--GQTI
.| | || |..|||||..|  ..|..|.  ||.  |.|.
ILNF-NQQYDKKVDIWSFGCIMYEIITNEQLFCSLGNTQ
Kinase 1168.AA CAMK 33-297 17 3.6e-45 143.07 In-house 1-419 (425) Show / Hide 
Range on Protein: 33-297
Range on HMM: 1-419/425
Sequence Identity: 17% (73 aa)

PLGQGGFGTVYKGKYGNQD--------------VAVKELKQY---------------IDNMGTVN------EYYQQEIETSKQIMS--------IDCEYI
 ||.|.||.|....  |                ||.| ..                 ||. .. .      .. .....   .||.        .| . |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VRVLGVVPT-------------------QYQCYVVM---DLCISD------LQKLRKESPN------------QRLDVMTALKCIKEICLGIKSLHMKNI
.. . |  .                   . ..| ||   ..|         ...... ...             |..   | .... || ... .| .||
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

THRDIKPDNIFIGKNQQDQ-------------LICKVGDFGLG--KNE-------------------------QNMISKVGTISYMA-PDMLDFS-----
 |||.||.|| . .|  |.                |. |||.   ...                         | |   .|| .||| | .|  .     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------NQKYTNKVDIWAIGVMAHELLTGTILFQGQ-------------TIDIIRNNILKSRNYKDWYKLSSSVAQTDFITQSFKHIQSES--------
       .. |. |.|.|..||.   .|.|.  |.|              ..  .  .|.| . . .....| . .     .... .  |..        
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCN---YGPEWWDDISDEFHHFVSQE

VINLIDMMLQKNPNDRKDINQI
...||  |||..|..|  | |.
CKDLIRKMLQVDPEKRMTIEQC
Kinase 1168.AA Pkinase 28-301 25 3.9e-45 160.67 Pfam 1-293 (293) Show / Hide 
Range on Protein: 28-301
Range on HMM: 1-293/293
Sequence Identity: 25% (78 aa)

IEKSRPLGQGGFGTVYKGKYGNQD--VAVKELKQYIDNMGTVNEYYQQ--EIETSKQIMSIDCEYIVRVLGVVPTQYQCYVVMDLC---ISDLQKLR---
... |..|.|.||.|||..  .    ||||..|   ..   ....     ||.  | .    ...||| .... .   .|.||..|    . .. |    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLN---HPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYI

-KESPNQRL--DVMTALKCIKEICLGIKSLHMKNITHRDIKPDNIFIGKNQQDQLICKVGDFGL-----GKNEQNMISKVGTISYMAPDMLDFSNQKYTN
   . . ..  .  .. .....|. |.. .| ..| |||.||.||.| .| .   . |..||||       | . | . .||. ||||  .  ..|.|. 
ST-WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-GGQYYGP

KVDIWAIGVMAHELLTGTILFQGQ------TIDIIRNNILKSRNYKDWYKLSS------SVAQTDFITQSFKHIQSESVINLIDMMLQKNPNDRKDINQI
|||.|..|.. .|.|.|  .|.|.      . . . ..|.. ..  ||....|      .  .  | .. | | .||. . .|. .|.|.|..|  . ||
KVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRH-W-HF-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQI

ITE--V
     .
LQHPWF
Kinase 1168.AA Ciliate-E2-Unclassified 28-298 22 9.3e-45 153.17 In-house 1-347 (352) Show / Hide 
Range on Protein: 28-298
Range on HMM: 1-347/352
Sequence Identity: 22% (81 aa)

IEKSRPLGQGGFGTVYKGKYGNQD--VAVKELKQYIDNM----GTVNEYYQQEIETSKQIM----------------SIDCEYIVRVLGVVPTQYQCYVV
 .. . .||||||.||| .  .|.   | |..|......     ...  . .|... ....                ......||. . .  ..  .| |
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

MDLC-ISDLQKLRKESPN---------------QRLDVMTAL-----KCIKEICLGIKSLHMKN-ITHRDIKPDNIFIGKNQQDQLICKVGDFGLGK---
|..|   ||..  |....               ....   |.     . ...|..|...|| || | ||||||.||.. .|..  . .|. |||. |   
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK-NYYIKIIDFGISKKYQ

----------------NEQNMISKVGTISYM----APDMLDFSNQKYT--NKVDIWAIGVMAHELLTGTILFQGQTIDI----------------IRNNI
                 .|.| ...||..||    || .|.  |.  .   |.|||. || ..|.|.|.  |.... ..                ...||
QNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

LKSRNYKDWYKL-----SSSVAQTDFITQSFKHIQSESVINLIDMMLQKNPNDRKDINQII
..   ......       .|  . |||.            .|.  ||.|||| | ...||.
KQKNIQFPKFPWQQIPKHWSPEAKDFIN------------DLLQKMLKKNPNKRITFEQIL
Kinase 1168.AA Ciliate-E2 28-298 21 6.6e-42 141.64 In-house 1-360 (365) Show / Hide 
Range on Protein: 28-298
Range on HMM: 1-360/365
Sequence Identity: 21% (82 aa)

IEKSRPLGQGGFGTVYKG--KYGNQDVAVKELKQY-------------IDNMGTVNEYYQQEIETSKQIM-----------------SIDCEYIVRVLGV
... . .|||.||.|||.  .  ....| |  .|.             | .| .....  ..|.  ..||                 .... .|..   .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VP--TQYQCYVVMDLCIS-DLQKLRKESP---------------NQRLDVMTALKC---------IKEICLGIKSLHMKN-ITHRDIKPDNIFIGKNQQD
    ..  .| ||..|   ||... |...               ......|. .           | .|.|....|| || | ||||||.||..      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

QLICKVGDFGLGKNEQNM--------ISK---------------------------VGTISYMAPDMLDFSN-------QKYTNKVDIWAIGVMAHELLT
   .|. |||| |. ..         ..|                           .||  |||| .|   .       . |. |.|||..||. .|.|.
---IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GTILFQGQTIDIIRNNILKSRNY----------KDWYKLSSSVAQTDFITQSFKHIQSESVINLIDM----MLQKNPNDRKD-INQII
|   |    ...| .. .. ...          ..| |             |.|.. |.....||      ||||.|. | . ..||.
GKPPF----QQQIKQCKIDFPCPEWQKDTQCIQCKW-K-------------SWKKW-SQECKDLIKKFGKRMLQKDPEKRITGWEQIL
Kinase 1168.AA ULK 28-303 25 8e-42 143.8 In-house 1-329 (329) Show / Hide 
Range on Protein: 28-303
Range on HMM: 1-329/329
Sequence Identity: 25% (85 aa)

IEKSRPLGQGGFGTVYKGK---YG---NQDVAVKE-LKQYIDNMGTVNE------YYQQEIETSKQIMSI-----DCEYIVRVLGVVPTQ--YQCYVVMD
..... ||.| ||.||||.    .   |..||.|  .||....    .|        ..||.. |.. |       ...||. . .  |.    .| .|.
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

LCIS-DLQKLRKESPN--------QRLDVMTALKCIKEICLGIKSLHMKNITHRDIKPDNIFIGKNQ---------QDQLICKVGDFGLGKN-EQN----
.|   ||... |.  .        .||  . |.. .| |. | | || .|| ||||||.|| | ..|         . . ..|..|||..|  . .    
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNDNMEQ

--MISKV------GTISYMAPDMLDFS--NQKYTNK-VDIWAIGVMAHELLTGTILFQGQTIDIIRNNILKSR--NYKDWYKLSSSVAQTDFITQSFKHI
  | . |      ||  ||||  |     ...|... .||| .|.. .|.|.|   |... .    ..|...   |.. |.           | .    .
QMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQ---------QIKKQPLQF

Q--------SESVINLIDMMLQKNPNDRKDINQIITEVEQ
.        |. ...||  |||....|| .. ...     
PKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 1168.AA TKL 34-233 19 6.2e-41 142.32 In-house 1-292 (364) Show / Hide 
Range on Protein: 34-233
Range on HMM: 1-292/364
Sequence Identity: 19% (58 aa)

LGQGGFGTVYKGKYGN----------QDVAVKELKQY--IDNMGTVNE-------------------YYQQEIETSKQIMSIDCEYIVRVLG-VVPTQY-
.|.||||.|||||. .          .||||| .|.     .. . .|                   . ..|.|  ... ..... ||. .| .   .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-----------QCYVVMDLC-ISDLQKLRKESPNQRLDVMTALKCIKEICLGIKSLHM--------KNITHRDIKPDNIFIGKNQQ----------DQLI
           |.. ||..|   .|  .              .. ...|..|.  ||.        ..| |||.|..||.. .| .          ..  
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

CKVGDFGLGKNEQNMIS-----------------------KVGTISYMAPDMLDFSNQ--------------KYTNKVDIWAIGVMAHELLTGTILFQGQ
||..|||| .. ... .                       ..||. .||| .|. ...              .|. |.|... |..  |.||. . ....
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY
Kinase 1168.AA ULK 28-303 25 2.3e-40 140.41 In-house 1-324 (324) Show / Hide 
Range on Protein: 28-303
Range on HMM: 1-324/324
Sequence Identity: 25% (85 aa)

IEKSRPLGQGGFG-TVYKG---KYG--NQDVAVKELK-QYIDNMGTVNE------YYQQEIETSKQIMSIDCEY--IVRVLGVVPTQ--YQCYVVMDLCI
..... ||.| || .||||   | .  ||.||.|    ... .    .|        ..||.. |.. .. ...  ||. . .  |.    .| .|..| 
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCN

S-DLQKLRKESPN-------QRLDVMTALKCIKEICLGIKSLHMKNITHRDIKPDNIFIGKNQ---------QDQLICKVGDFGLGKNEQN-------MI
  ||... |.  .       .||  . |.. .| || | | || .|| ||||||.|| | ..|         . . ..|..|||..|  .|       . 
GGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHP-NGVLKIADFGFAKHVDNNNMEQQMCQ

SKV------GTISYMAPDMLDFS--NQKYTNK-VDIWAIGVMAHELLTGTILFQGQ-TIDIIRNNILKSRN---YKDWYKLSSSVAQTDFITQSFKHIQ-
. |      ||  ||||  |     ...|... .||| .|.. .|.|.|   |... . .... ..   .|   .    ..     . .|   . | .. 
TCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSWFNDQYLY-IQKLINNGKEQ----QIYIKNQPIQFPKPP-KDPKI

SESVINLIDMMLQKNPNDRKDINQIITEVEQ
|. ...||  |||....|| .. .|.     
SPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 1168.AA CMGC 28-234 16 1.3e-33 107.08 In-house 1-347 (513) Show / Hide 
Range on Protein: 28-234
Range on HMM: 1-347/513
Sequence Identity: 16% (58 aa)

IEKSRPLGQGGFGTVYKGKY----------------GNQDVAVKELK-QYIDNMG------------TVNEYYQQEIETSKQI--------------MSI
 |. ...|.| .|.|||..                 .|. ||.| .| .  .  .            . .     ||.  |..              .. 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALR----EIKILKHLNKNHDPNWQRRDDPDNK

DCEYIVRVLGVVPTQY-----------------QCYVVMDLCISDLQKLRKESP--------------------------NQRLDVMTALKCIKEICLGI
. ..||. . .. .                   . | |....  || .. |. .                           . . .      .. |. |.
HHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGL

K--SLHMKN--ITHRDIKPDNIFIGKNQQ----------------DQLICKVGDFGLGKNEQN-------------------------MISKVGTISYMA
|   .| ..  | |||.|| || | .| .                .. . |..|||| . . .                         . . | |  | |
KLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRA

P----DMLDFSN----QKYTNKVDIWAIGVMAHELLTG--------TILFQGQT
|     . . .|    ..|| ..|.|..| .  |..||         .||.|..
PEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHS
Kinase 1168.AA STE 28-296 17 2.9e-32 111.29 In-house 1-350 (359) Show / Hide 
Range on Protein: 28-296
Range on HMM: 1-350/359
Sequence Identity: 17% (67 aa)

IEKSRPLGQGGFGTVYKGKYGNQD-----------------VAVKELK-----QYIDN------MGTVNEYYQ----QEIETSKQIMSIDCEYIVRVLGV
 |. . .|.|.||||||... ...                 .|.|...     ... .        ..|.  .    .||.. |.  .. ...||. .| 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHM-HPNIVKYYGC

VPTQY-------QCYVVMDLCI-SDLQKLRKE--SPNQRLD----------VMTALKCIKEICLG-IKSLHMKNITHRDIKPDNIFIGKNQQDQLICKVG
            .....| ..    | .. |.  .....|.               . ...|. |  . || ..| ||||||.||..         .|  
YFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL---------VKLC

DFGLGK--------------------NEQNMISKVGTISYMAPDMLD---FS-NQKYTNKVDIWAIGVMAHELLTGTILFQGQTIDIIRNNIL-------
|||. .                    . |.  . |||  .||| ...    . ...|. |.||| .| .. |..||   .   .      .|.       
DFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQ

----------KSRNYKDWYK------------LSSSVAQTDFITQSFKHIQSESVINLIDMMLQKNPNDRKDINQ
          ..   .|  .            .              .|  |.. .. |.  |||.||.| . .|
QFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTT-------------YPHKWSPEFKDFINKCLQKDPNKRPTASQ
Kinase 1168.AA CAMK-Unique 144-273 20 4.9e-27 86.12 In-house 173-349 (363) Show / Hide 
Range on Protein: 144-273
Range on HMM: 173-349/363
Sequence Identity: 20% (37 aa)

LHMKNITHRDIKPDNIFIGKNQQD------------QLICKVGDFGLGKNEQNMISK------VGTISYMAP--------------DMLDFSNQKYTNKV
.| ..| |||.|..|| . .. .|            ..  |. |||| . ... ..       .||..||||               ....  |.|  ..
MHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINM--QCYDQQC

----DIWAIGVMAHELLTGTILFQGQTID--------IIRNNILKSRN---YKDWYKLS--SSVAQTDFITQSFKHIQS
    |||..||.....|.|   | ....|         |. .|.| .     .... ..   |.. .||... .. ...
SPASDIWSLGVIMYYMLCGCPPFDCECEDRDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPD
Kinase 1168.AA TyrKc 28-301 21 2.9e-16 40.35 SMART 1-280 (280) Show / Hide 
Range on Protein: 28-301
Range on HMM: 1-280/280
Sequence Identity: 21% (68 aa)

IEKSRPLGQGGFGTVYKGKYGNQDVAVKELKQYIDNMGTVNEYYQQEIETSKQIMSI--DCEYIVRVLGVVPTQ-------YQCYVVMDLCIS-DLQKLR
|.. . || | ||.||||..  ..|||| || .        |   .|..     ...  . . ||| .||. .|        . ..|| ..   ||..  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA------REDFMREARI---MCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

KESPNQRLDVMTALKCIKEICLGIKSLHMKNITHRDIKPDNIFIGKNQQDQLICKVGDFGLGKNEQNM----------------ISK-VGTISYMAPDML
... .. | . . |.    |. |   || ||. |||.   |. .|.|.    ..|..|||| ..  .                  .| .  |  |||  .
RKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI

DFSNQKYTNKVDIWAIGVMAHELLTGTILFQGQ-----TIDIIRNNILKSRNYKDWYKL----SSSVAQTDFITQSFKHIQSESVINLIDMMLQKNPNDR
     |.| | |.|. ||.  |..|               ..   . .|.... .  .     |            |  . .. . ... .  . .|.||
--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------F-VCCPDEMYQIMKQCWHEDPEDR

KDINQIITEV
   ..|. . 
PTFSEIHECF
Kinase 1168.AA Pkinase_Tyr 28-178 30 1.8e-15 53.0 Pfam 1-157 (270) Show / Hide 
Range on Protein: 28-178
Range on HMM: 1-157/270
Sequence Identity: 30% (50 aa)

IEKSRPLGQGGFGTVYKGKYG------NQDVAVKELKQYIDNMGTVNEY-YQQEIETSKQIMS-I-DCEYIVRVLGVVP-TQYQ--CYVVMDLCIS-DLQ
|.. . ||.| ||.||||..       ...|||| ||.     |.  |  ....     .||. . ... ||| .||.   . .   |.|| ..   || 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE-----GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL

K-LRKE-SPNQRLDVMTALKCIKEICLGIKSLHMKNITHRDIKPDNIFIGKNQQDQLICKVGDFGL
. |||  ...|.|.. . |.   .|. |   |. ||. |||.   |. ...    ....|..||||
DYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----NNVVKICDFGL
Kinase 1168.AA CAMK-Unique 28-46 36 0.000849 8.19 In-house 1-19 (363) Show / Hide 
Range on Protein: 28-46
Range on HMM: 1-19/363
Sequence Identity: 36% (7 aa)

IEKSRPLGQGGFGTVYKGK
... |..|.|.|| ||...
YKMHRIIGHGNFGHVYECM
Kinase 1168.AA Ciliate-B1 284-302 42 0.006432 6.19 In-house 272-290 (290) Show / Hide 
Range on Protein: 284-302
Range on HMM: 272-290/290
Sequence Identity: 42% (8 aa)

LQKNPNDRKDINQIITEVE
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LQPDPENRITIDQIIDRLM