15778

Species: Tetrahymena
Alias: 349.m00005, 1065, TTHERM_01365630, 15778, PreTt15778
External Links: Tetrahymena Genome Database (TGD) ,
Annotation:

Classification

Group: Other
Family: Ciliate-C8
Subfamily: C8

Sequence

Name Sequence Type Origin Length Description Download
15778.AA Protein None 168 None Fasta, JSON
15778.kin_dom Protein Kinase Domain None 69 None Fasta, JSON
15778.NA RNA None 507 None Fasta, JSON

Protein domain

Protein domains of 15778.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 15778.AA C8 46-155 54 4.2e-49 168.56 In-house 1-110 (226) Show / Hide
Range on Protein: 46-155
Range on HMM: 1-110/226
Sequence Identity: 54% (60 aa)

FQNFEYLSSGAYSLVLKAYNSQQNRQVALKFLGSSNKEYNNGIESLKKEYEMLQKFSQSQFLVNVYDCFYLMEEQEDEDEDGNDIIVQTGVKSFFVMEME
|.||.|||.|||..||||.|...||...|||. ..||. ...|||..|||||.|.|.|..|.||.|||||.|.|...|....|..|||| .||.||||||
FNNFQYLSFGAYGMVLKAKNVKDNREIVLKFQKCQNKQDIQNIESIMKEYEMPQVFQQYDFYVNEYDCFYEMYEVFEEEKCSNEKIVQTEEKSCFVMEME

LCESKQKSHF
|||.. |  .
LCEQNLKQLY

Kinase 15778.AA Ciliate-C8 55-155 56 8.6e-46 158.45 In-house 1-106 (238) Show / Hide
Range on Protein: 55-155
Range on HMM: 1-106/238
Sequence Identity: 56% (60 aa)

GAYSLVLKAYNSQQNRQVALKFLGSSNKEYNNGIESLKKEYEMLQKFSQSQFLVNVYDCFYLMEEQEDEDEDGNDIIVQTGVK---SFFVMEMELCESK-
||...||||.|..|||.|||||. ..||. .|..|...|||||...|.|..|.|.||||||||||...||.||||.|||| .|   ||||||||.|... 
GAFGMVLKAQNKKQNRKVALKFRECVNKIQKNQMEHEIKEYEMIMQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKKSFFVMEMEKCQQNC

-QKSHF
  |. |
NLKQYF

Kinase 15778.AA C2 55-155 35 1.2e-26 88.18 In-house 1-109 (245) Show / Hide
Range on Protein: 55-155
Range on HMM: 1-109/245
Sequence Identity: 35% (39 aa)

GAYSLVLKAYNSQQNRQVALKFLGSSNKEYNNGIESLKKEYEMLQKFSQSQFLVNVYDCFYLMEE-QEDEDEDGNDIIVQTGV--------KSFFVMEME
|| .|||||.| .|||.||||       .  || ... |||....... . ....||..||| .. .|||||| ......           |.|.|.|.|
GAFGLVLKAFNKKQNRHVALKIQECQSNDI-NGMHEVQKEYGIMRQCQNMPYIIKVYNYFYLTVNKKEDEDEDNDEEEKEQENIKKQKNEKKIFVVYEQE

LCESKQKSHF
 |... |. |
FCQGNLKQYF

Kinase 15778.AA CMGC 46-115 14 6.5e-08 21.1 In-house 1-108 (513) Show / Hide
Range on Protein: 46-115
Range on HMM: 1-108/513
Sequence Identity: 14% (16 aa)

FQNFEYLSSGAYSLVLKAYN--------------SQQNRQVALKFLGSSNKEYNNGIE----------SLKKEYEMLQKFS----------------QSQ
... ... .|.|. | |...               . |..||.| . .... | ..            .   | ..|....                .  
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKI-KNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHN

FLVNVYDCFY
 .|. ||.||
NIVKLYDIFY

Kinase 15778.AA STE20 46-119 19 9.8e-08 24.67 In-house 1-82 (288) Show / Hide
Range on Protein: 46-119
Range on HMM: 1-82/288
Sequence Identity: 19% (16 aa)

FQNFEYLSSGAYSLVLKAYNSQQNRQ----VALKFLGSSNKEYN-NGIESLKKEYEMLQKFSQSQFLVNVYDCFYLM----EE
....| . .|.|  | |||. . ...    || | .  ....   . .|...||. .....  ..  |. |.... .    .|
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK-HPNIVKYYGSYLKDDTCDDE

Kinase 15778.AA STE 46-123 17 3.5e-07 21.53 In-house 1-111 (359) Show / Hide
Range on Protein: 46-123
Range on HMM: 1-111/359
Sequence Identity: 17% (19 aa)

FQNFEYLSSGAYSLVLKAYNS------QQNRQ---------VALKFLGSSNKE----------YNNG----IESLKKEYEMLQKFSQ-SQFLVNVYDCFY
... | . .||.  | ||.|       . ...         .| | .  .|..          ..|     .....|| ....|... ... |. |.|..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

LM---EEQEDE
     ....||
KEGHNHKNDDE

Kinase 15778.AA MAPK 46-75 25 4.4e-07 20.28 In-house 1-36 (328) Show / Hide
Range on Protein: 46-75
Range on HMM: 1-36/328
Sequence Identity: 25% (9 aa)

FQNFEYLSSGAYSLVLKAYNSQ------QNRQVALK
.|. ... .||| .| .|.         ....||.|
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIK

Kinase 15778.AA Ciliate-E1 52-116 23 6.4e-07 19.06 In-house 1-66 (202) Show / Hide
Range on Protein: 52-116
Range on HMM: 1-66/202
Sequence Identity: 23% (16 aa)

LSSGAYSLVLKAYNSQQN-RQVALKFLGSSNKEYNNGIESLKKEYE-MLQKFSQSQFLVNVYDCFYL
...| .|.|.||.. ..| .|||.|.     ..  | .....|||  ... | . . .....|....
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKI

Kinase 15778.AA ULK 46-115 21 1e-06 19.96 In-house 1-85 (324) Show / Hide
Range on Protein: 46-115
Range on HMM: 1-85/324
Sequence Identity: 21% (18 aa)

FQNFEYLSSGAYS-LVLKAYNSQQ---NRQVALKFLG---SSNKEYNNG----IESLKKEYEMLQKFS--QSQF--LVNVYDCFY
..  . | .|..   | |..| ..   | .|| |       ..|....     ...||.| . ..|.   ....   |  ||.|.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNHHIVKLYDWFE

Kinase 15778.AA Ciliate-E3 46-115 24 1.1e-05 14.09 In-house 1-72 (202) Show / Hide
Range on Protein: 46-115
Range on HMM: 1-72/202
Sequence Identity: 24% (18 aa)

FQNFEYLSSGAYSLVLKAYNSQQNRQVALKFLGSSNKEY---NNGIESLKKEYEMLQKFSQSQFLVNVYDCFY
.     |  | ...| ||...|.|..|| | .  .|.           . .|  . |..  ||..| ..| .|
YTVQQILGCGQFGRVYKAFDFQNNQDVAIKAIICQNQQNEGVGEQFQKTQQEFQNCQQI-NSQNVVKCHDQYY

Kinase 15778.AA Pkinase 46-115 16 0.00016 17.07 Pfam 1-70 (293) Show / Hide
Range on Protein: 46-115
Range on HMM: 1-70/293
Sequence Identity: 16% (12 aa)

FQNFEYLSSGAYSLVLKAYNSQQNRQVALKFLGSSNKEYNNGIESLK-KEYEMLQKFSQSQFLVNVYDCFY
..  . . ||... | |...   ...||.| .  .... .  .. ..  | ...... .. . |  ||.|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFE