16697

Species: Tetrahymena
Alias: 1042, 1746.m00002, TTHERM_02510180, 16697, PreTt16697
External Links: Tetrahymena Genome Database (TGD) ,
Annotation:

Classification

Group: Other
Family: Ciliate-C8
Subfamily: C8

Sequence

Name Sequence Type Origin Length Description Download
16697.AA Protein None 232 None Fasta, JSON
16697.kin_dom Protein Kinase Domain None 60 None Fasta, JSON
16697.NA RNA None 696 None Fasta, JSON

Protein domain

Protein domains of 16697.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 16697.AA Ciliate-C8 2-149 48 2.8e-55 189.97 In-house 101-238 (238) Show / Hide
Range on Protein: 2-149
Range on HMM: 101-238/238
Sequence Identity: 48% (79 aa)

NLKQLFDFLKSTQLP-SKEIKEIIAIQMLEGLNNLHVKNIMHRDIKPHNFLVCPSQTYGFTIKLCKKFEFLQNLSIQKIFENQGDLGFASAVTKSKSHYI
||||.||... .|.. |...||||||||....|.||..|||||||||||||||..|.|..|||||. |     . .|      .|.||||...|.||||.
NLKQYFDRCRKKQSYPSQQMKEIIAIQMIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCD-F-----K-KQ------CDFGFASQLPKNKSHYH

SKK--RTDAY-----------FAPEVEKGQSRIQVFKQNQSLNFQFNFNVQKSDLFSLGLVL
|||   ||.|           |||||||.|||||        . .| ..   ||..|.||||
SKKFKGTDQYIEMYFCGNWGYFAPEVEKKQSRIQ--------SDIFSKK---SDSYSVGLVL

Kinase 16697.AA C8 1-121 53 1.7e-49 169.96 In-house 104-216 (226) Show / Hide
Range on Protein: 1-121
Range on HMM: 104-216/226
Sequence Identity: 53% (71 aa)

ENLKQLFDFLKSTQLP-SKEIKEIIAIQMLEGLNNLHVKNIMHRDIKPHNFLVCPSQTYGFTIKLCKKFEFLQNLSIQKIFENQGDLGFASAVTKSKSHY
.|||||.|... .|.. |||.||||||||..|.|..|.||||||||||||||||..|.|||.||||                   |.||||.|.|.|||.
QNLKQLYDERRNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLC-------------------DFGFASQVSKNKSHI

ISKK----RTDAYFAPEVEKG------QSRIQ
.|||     |.||||||.||.      |.|||
QSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQ

Kinase 16697.AA C2 2-162 32 4.4e-26 86.17 In-house 104-245 (245) Show / Hide
Range on Protein: 2-162
Range on HMM: 104-245/245
Sequence Identity: 32% (56 aa)

NLKQLFDFLKSTQ-LPSKEIKEIIAIQMLEGLNNLHVKNIMHRDIKPHNFLVCPSQTYGFTIKLC-KKFEFLQNLSIQKIFENQGDLGFASAVTKSKSHY
|||| |. ..  .  |....|.|.||||. . | || ..| |||||| |||.  .|    |||||    .. |.                          
NLKQYFNRCRKQNSYPCQQMKMIMAIQMMDSINYLHRFDIVHRDIKPSNFLYQFDQQGIPTIKLCDYHIQY-QK-K------------------------

ISKKRTDAYFAPEVEKGQSRIQV--FKQNQSLNFQ-FNFNVQK------SDLFS-LGLVLLELDNLKVLNENW
     .|  ||  ... .||| .  ||  |. ..  | . |..      ||||| .|.||||||| .  . . 
-----CDFDFASKLKYNKSRIHFSKFKWTQQYYQHIFAPEVYQNIYKKNSDLFSTVGYVLLELDNMQQYTICC

Kinase 16697.AA Ciliate-E2a 4-51 40 2e-12 32.89 In-house 84-134 (275) Show / Hide
Range on Protein: 4-51
Range on HMM: 84-134/275
Sequence Identity: 40% (21 aa)

KQLFDFLKSTQ-LPSK--EIKEIIAIQML-EGLNNLHVKNIMHRDIKPHNFL
..|.| .|  . . ..  ||..|.  |.| .||...| .||||||.|| |.|
GELYDKIKQCKRFFEEIQEICDIMQ-QLLWQGLHYMHQRNIMHRDLKPENIL

Kinase 16697.AA CMGC 6-65 19 2.2e-12 36.1 In-house 141-246 (513) Show / Hide
Range on Protein: 6-65
Range on HMM: 141-246/513
Sequence Identity: 19% (21 aa)

LFDFLKSTQ----------LPSKE------------IKEII-----AIQMLEGLN--NLHVKN--IMHRDIKPHNFLVCPSQTY----------------
|....|..|          |.  .            || ..     . |.|.||.   .| ..  |.|||.|| | |...  ..                
LYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQK

GFTIKLC
 ...|.|
NGRLKIC

Kinase 16697.AA CDK-DD1 27-54 57 4.6e-12 32.92 In-house 106-133 (379) Show / Hide
Range on Protein: 27-54
Range on HMM: 106-133/379
Sequence Identity: 57% (16 aa)

QMLEGLNNLHVKNIMHRDIKPHNFLVCP
| |||.| .|.  |||||||| | |. .
QLLEGINECHNQGIMHRDIKPANLLINN

Kinase 16697.AA CK1-Unclassified 24-52 58 1.7e-11 30.19 In-house 109-137 (244) Show / Hide
Range on Protein: 24-52
Range on HMM: 109-137/244
Sequence Identity: 58% (17 aa)

IAIQMLEGLNNLHVKNIMHRDIKPHNFLV
|| ||.. . .|| ||. |||||| |||.
IADQMIQRIEYLHNKNFIHRDIKPDNFLM

Kinase 16697.AA Ciliate-E1 3-108 23 3e-11 33.31 In-house 93-202 (202) Show / Hide
Range on Protein: 3-108
Range on HMM: 93-202/202
Sequence Identity: 23% (27 aa)

LKQLFDFLKSTQLPSKEI-KEIIAIQMLEGLNNLHVKNIMHRDIKPHNFLVCPSQTYGFT-IKLCKKFEFLQNLSIQKIFENQGDLGFASAVTKS-----
| .... ....|   ..  |. |..|...||. || .||.||||||.| |.. .  | .. . ..|   ||.| ..| . ...    ...   .      
L-EYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISK---FLKNNQNQQCQYKGYTHYYYPPEQYNCPEQE

-KSHYISKKRTDAY
 .  .. .. .| |
HNKNQKINYKSDIY

Kinase 16697.AA RCK 6-65 31 3.8e-11 31.32 In-house 86-156 (298) Show / Hide
Range on Protein: 6-65
Range on HMM: 86-156/298
Sequence Identity: 31% (23 aa)

LFDFLKS----TQ-LPSKE--IKEIIAIQMLEGLNNLHVKNIMHRDIKPHNFLVCPSQTY-----GFTIKLC
|. ..|.    .. ||...  || |.  | | ||. .| ....|||.|| | ....|| |      ..||..
LYQMMKDFKERRKYLPENQRSIKNIM-YQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHIKIA

Kinase 16697.AA Ciliate-B2 27-61 37 4.3e-11 22.24 In-house 112-146 (197) Show / Hide
Range on Protein: 27-61
Range on HMM: 112-146/197
Sequence Identity: 37% (13 aa)

QMLEGLNNLHVKNIMHRDIKPHNFLVCPSQTYGFT
|...||  ....||.| |||| | |.  .  | ..
QLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYC

Kinase 16697.AA Pkinase 6-65 30 7.6e-10 35.9 Pfam 91-154 (293) Show / Hide
Range on Protein: 6-65
Range on HMM: 91-154/293
Sequence Identity: 30% (20 aa)

LFDFLK---STQL--PSKEIKEIIAIQMLEGLNNLHVKNIMHRDIKPHNFLVCPSQTYGFTIKLC
|||...   .. .  . .|.| ..  |.|.||. .| ..|.|||.|| |.|.    . . ..|.|
LFDYISTWRHGCFYFSEWECKFYMY-QILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKIC

Kinase 16697.AA S_TKc 1-215 12 2.3e-05 -98.2 SMART 19-231 (231) Show / Hide
Range on Protein: 1-215
Range on HMM: 19-231/231
Sequence Identity: 12% (37 aa)

ENLK----------------------------------------------------QLFDFLKSTQ-------LPSKEIKEIIAIQMLEGLNNLHVKNIM
 . |                                                     |||..|. .       .|  ... ... |....|. .| ..|.
RHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMY-QICCALEYCHSHGII

HRDIKPHNFLVCPSQTYGFTIKLC-----KKFEFLQNLSIQKIFENQGDLGFASAVTKSKSHYISKKRTDAYFAPEVEKGQSRIQVFKQNQSLNFQFNFN
|||.|| | |..       .||.|     ...                                .   |  | ||||                     ..
HRDLKPENILLDE------HIKICDFGLARQL-------------------------------TTFCGTPWYMAPEVL-------------------GYG

VQKSDLFSLGLVLLELDNLKVLNENWIDYFTKGEIYQGKSIASNYQIDRNSNIYKIAQICLKPNYLERTTSGDLLS--------ELI
  |.|  |.| .| |.   . . .      .  ....             .    . . ||. .  .| |  ..|         . .
KCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 16697.AA C8 132-149 55 0.0003 10.78 In-house 209-226 (226) Show / Hide
Range on Protein: 132-149
Range on HMM: 209-226/226
Sequence Identity: 55% (10 aa)

QFNFNVQKSDLFSLGLVL
|. ..  .|||||.||||
QYKQYRIQSDLFSVGLVL

Kinase 16697.AA Ciliate-B2 139-146 50 0.009183 2.21 In-house 190-197 (197) Show / Hide
Range on Protein: 139-146
Range on HMM: 190-197/197
Sequence Identity: 50% (4 aa)

KSDLFSLG
.|| .|.|
QSDIYSMG

Kinase 16697.AA Ciliate-E1 143-190 22 0.268856 0.56 In-house 153-202 (202) Show / Hide
Range on Protein: 143-190
Range on HMM: 153-202/202
Sequence Identity: 22% (11 aa)

FSLGLVLLELDNLKVLNENWIDYFTKGEIYQGKSI--ASNYQIDRNSNIY
|.....| . .|  .  .. ..|.   | |. .      |..|. .|.||
FGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY