Gene 13479 (Tetrahymena)
13479
Group:
Other
Family:
Ciliate-E1
Sequence
Protein domains of 13479.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 13479.AA | Ciliate-A8 | 88-177 | 41 | 2e-24 | 81.56 | In-house | 1-90 (151) | Show / Hide |
Range on Protein: 88-177 Range on HMM: 1-90/151 Sequence Identity: 41% (38 aa) YVYEKEISRSSSSLVVQAKSLKNNNSKVAIKILNY-EYNSKINIQKLKKQVEFLDSLKGEKYVLQFIEIIQDLTYGITAIVTEYCESIFFN |.|.| . |.||||.|.. .. .|||||..| . ||| ....|... . .|.|||.||.|| |||. .| .|||||.|.. |. YKYQKVLEKGDFSYVVQAYSINHQC-QVAIKIIKYMNQQNKINDKEFEKCIQAMQKIKNEKYILQIIECIQDKEQGFIAIVTEFCDCFDFY |
|||||||||
| Kinase | 13479.AA | Ciliate-E1 | 94-187 | 27 | 1.5e-21 | 67.19 | In-house | 1-110 (202) | Show / Hide |
Range on Protein: 94-187 Range on HMM: 1-110/202 Sequence Identity: 27% (31 aa) ISRSSSSLVVQAKSLKNNNSKVAIKILNYEYN-SKINIQKLKKQVE-FLDSLKGEKYVLQFIEIIQ-DLTYGITAIVTEYCESIFFNLN----------- |...|.|.|..||. .||...||.|| |...| .....|...|. ... .|.|.|..|.|..|. |. |....|....|.| . .|. IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC ---DQLFNFQK .. |.||. QQNQNQFTFQQ |
|||||||||
| Kinase | 13479.AA | Ciliate-E2-Unclassified | 218-284 | 19 | 7.2e-09 | 26.93 | In-house | 170-262 (352) | Show / Hide |
Range on Protein: 218-284 Range on HMM: 170-262/352 Sequence Identity: 19% (18 aa) IEPEKIFYSASNN--QFLLSYLSFTR-----------------LIHSENNEQQQGNLNYQ----SPEVIDKKKPYT---ITADIFSIGVILLE | || |... ... . .. ... . . ... .. |..||. .|||........ . .||.| |||| | IKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYE |
|||||||||
| Kinase | 13479.AA | S_TKc | 88-349 | 12 | 1.5e-08 | -51.42 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 88-349
Range on HMM: 1-231/231
Sequence Identity: 12% (39 aa)
YVYEKEISRSSSSLVVQAKSLKNNNSKVAIKILNYEYNSKINIQKLKKQVEFLDSLKGEKYVLQFIEIIQDLTYGITAIVTEYCE----SIFFNLNDQL-
| ..| . . . | ... | . .|||||.. ..... .. | . . ... ......|| . .|.|||. . | . ..
YEILRKIGKGAFGKVYKCRHKK-TGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGR
------FNFQKYSKFS--------------------------LNSRDKQAKNRVSLC---FGEKGKSLRYIEPEKIFYSASNNQFLLSYLSFTRLIHSEN
|. .. |.. .. .| . .
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL-----------------------------------
NEQQQGNLNYQSPEVIDKKKPYTI-TADIFSIGVILLEALLQRKLKGMEYLKLKSQSLMSVLPDLLNEQNRQFVTNILSKMVDPDYCKRSQPINILQ---
. | ..| .|||. .|. .|. |.|.|| | | . . .. .. . . ... ...|. . | || .||
-TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-----------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEW
--LLNKLK
.
DIKCHPWF
|
|||||||||
| Kinase | 13479.AA | TKL | 245-284 | 20 | 9.7e-08 | 23.95 | In-house | 227-281 (364) | Show / Hide |
Range on Protein: 245-284 Range on HMM: 227-281/364 Sequence Identity: 20% (11 aa) SENNEQQQGNLNYQSPEVIDKK---------------KPYTITADIFSIGVILLE .... | |.... .|||.... ..|. .|..| |..| | RKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWE |
|||||||||
| Kinase | 13479.AA | C8 | 216-282 | 23 | 1.4e-07 | 22.46 | In-house | 147-226 (226) | Show / Hide |
Range on Protein: 216-282 Range on HMM: 147-226/226 Sequence Identity: 23% (19 aa) RYIEPEKIFYSASNNQF---LLSYLSFTRLIHSENN--EQQQ----GNLNYQSPEVIDK----KKPYTITADIFSIGVIL | | |. . ...|. |. . | . .. . .... |.. | ||.. | | |.| |.||.|..| RDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL |
|||||||||
| Kinase | 13479.AA | CAMK1 | 257-282 | 50 | 3.8e-07 | 16.75 | In-house | 179-206 (276) | Show / Hide |
Range on Protein: 257-282 Range on HMM: 179-206/276 Sequence Identity: 50% (14 aa) YQSPEVIDKK--KPYTITADIFSIGVIL |. |||. | ||| . |..|||||. YVAPEVLECKKDKPYDKACDMWSIGVIT |
|||||||||
| Kinase | 13479.AA | Ciliate-E2 | 250-282 | 34 | 5.1e-07 | 20.12 | In-house | 246-286 (365) | Show / Hide |
Range on Protein: 250-282 Range on HMM: 246-286/365 Sequence Identity: 34% (14 aa) QQQGNLNYQSPEVIDKKKP--------YTITADIFSIGVIL .. |...|..||.. .|| |. .||.|.|||| TICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL |
|||||||||
| Kinase | 13479.AA | MLK | 251-282 | 32 | 9.8e-07 | 19.53 | In-house | 193-226 (291) | Show / Hide |
Range on Protein: 251-282 Range on HMM: 193-226/291 Sequence Identity: 32% (11 aa) QQGNLNYQSPEVID--KKKPYTITADIFSIGVIL ..|.. . .|||| . .|.. .|..|.||.| NAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVL |
|||||||||
| Kinase | 13479.AA | CAMK | 253-282 | 29 | 1e-06 | 16.84 | In-house | 281-324 (425) | Show / Hide |
Range on Protein: 253-282 Range on HMM: 281-324/425 Sequence Identity: 29% (13 aa) GNLNYQS-PEVIDK-------------KKPYTITADIFSIGVIL | . | . |||. . |..|. .|. |.|||| GTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVIL |
|||||||||
| Kinase | 13479.AA | ULK | 257-282 | 33 | 5e-06 | 17.25 | In-house | 217-246 (329) | Show / Hide |
Range on Protein: 257-282 Range on HMM: 217-246/329 Sequence Identity: 33% (10 aa) YQSPEVID---KKKPYT-ITADIFSIGVIL | .|... ..|||. ..||.|.|.|. YMAPQILQGQGEQKPYYDYKCDIWSLGCIF |
|||||||||
| Kinase | 13479.AA | Ciliate-E1 | 218-276 | 15 | 4.2e-05 | 13.09 | In-house | 135-202 (202) | Show / Hide |
Range on Protein: 218-276 Range on HMM: 135-202/202 Sequence Identity: 15% (11 aa) IEPEKIFYSASNNQFLLSYLSFTRLIHSENNEQQ---QGNLNYQSPEVI-------DKKKPYTITADIF | |..| .. . ...... .. ... ...|.|. . .|..||.. .|...... ||. IKPQNILINNQ-GNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY |
|||||||||
| Kinase | 13479.AA | Ciliate-A8 | 218-233 | 56 | 0.000174 | 12.26 | In-house | 136-151 (151) | Show / Hide |
Range on Protein: 218-233 Range on HMM: 136-151/151 Sequence Identity: 56% (9 aa) IEPEKIFYSASNNQFL | |. |.|| |.|||. IKPQNILYSWSKNQFI |
|||||||||
| Kinase | 13479.AA | Pkinase | 244-289 | 32 | 0.000328 | 15.97 | Pfam | 165-209 (293) | Show / Hide |
Range on Protein: 244-289 Range on HMM: 165-209/293 Sequence Identity: 32% (15 aa) HSENNEQQQGNLNYQSPEVIDKKKPYTITADIFSIGVILLEALLQR ... . | ..| .|||| . ..|. .|..|.|.|| | |. | NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGR |
|||||||||
| Kinase | 13479.AA | C8 | 83-140 | 22 | 0.007879 | 5.79 | In-house | 1-53 (226) | Show / Hide |
Range on Protein: 83-140 Range on HMM: 1-53/226 Sequence Identity: 22% (13 aa) LKTFGYVYEKEISRSSSSLVVQAKSLKNNNSKVAIKILNYEYN-SKINIQKLKKQVEFL .. | | .| . ..|..|| .| .| ....|.. .. . . ||....|..| . FNNFQY-----LSFGAYGMVLKAKNVK-DNREIVLKFQKCQNKQDIQNIESIMKEYEMP |
|||||||||
| Kinase | 13479.AA | TKL | 94-172 | 12 | 0.00801 | 6.01 | In-house | 1-121 (364) | Show / Hide |
Range on Protein: 94-172
Range on HMM: 1-121/364
Sequence Identity: 12% (15 aa)
ISRSSSSLVVQAKSLKNN-------NSKVAIKILNYEYNSKINI----------------------QKLKKQVEFLDSLKG--EKYVLQFIEIIQDLTYG
| . ... | ..| .. . ||.|... ..... .. . .. .| . ... ..||. . .. ..|
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
I-----------TAIVTEYCE
.||.|||.
CVCMHPVGPWGQLCIVMEYCP
|
|||||||||
| Kinase | 13479.AA | CAMK | 93-172 | 13 | 0.015889 | 3.15 | In-house | 1-143 (425) | Show / Hide |
Range on Protein: 93-172 Range on HMM: 1-143/425 Sequence Identity: 13% (19 aa) EISRSSSSLVVQAKSLKNNN-----------SKVAIKILNYEYNSKI--------------------------NIQKLKKQVEFLDSLKG------EKYV .. | | . | .. .... ||||||.. . .. . ..... .| . .|.| . . TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI LQFIEIIQDLTYGI-----------------TAIVT---EYCE ....|...| .|. .|. |||. IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCS |
|||||||||
| Kinase | 13479.AA | CAMK1 | 88-146 | 26 | 0.019709 | 2.81 | In-house | 1-55 (276) | Show / Hide |
Range on Protein: 88-146 Range on HMM: 1-55/276 Sequence Identity: 26% (16 aa) YVYEKEISRSSSSLVVQAKSLKN--NNSKVAIKILNYEYNSKINIQKLKKQVEFLDSLKGE |. ||| | . | |.... .. |. ..|||... | ...| . | . ...|. | YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDK----KKFMKKKDMQ-K-QEALENE |
|||||||||
| Kinase | 13479.AA | ULK | 102-172 | 20 | 0.089443 | 2.08 | In-house | 15-103 (329) | Show / Hide |
Range on Protein: 102-172 Range on HMM: 15-103/329 Sequence Identity: 20% (19 aa) VVQAKSLKNN---NSKVAIKILNYEYNSKIN--------IQKLKKQVEFLDSLK---GEKY----VLQFIEIIQDL----TYGITAIVTEYCE | ... |.. | |||.|.. .. ...| .| ||. .. . || . |. . ..... .. .| |..|||. VYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIY----IIMEYCN |
|||||||||
| Kinase | 13479.AA | Pkinase | 88-172 | 18 | 0.251477 | 5.77 | Pfam | 1-83 (293) | Show / Hide |
Range on Protein: 88-172 Range on HMM: 1-83/293 Sequence Identity: 18% (16 aa) YVYEKEISRSSSSLVVQAKSLKNNNSKVAIKILNYEYNSKINIQKLKK--QVEFLDSLKGEKYVLQFIEIIQDLTYGITAIVTEYCE |. .. | . |.. | ... ... .||.||.... ... | . . .. . .|. . ....... .| . .|.|||| YHIGRKIGSGSFGCVYKCHHKGTGK-IVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPN-IVRLYDWFED--KDHIYMVMEYCE |
|||||||||