18319

Species: Tetrahymena
Alias: 1069, 18319, PreTt18319, 296.m00007, TTHERM_01257640
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E1

Sequence

Name Sequence Type Origin Length Description Download
18319.AA Protein None 1994 None Fasta, JSON
18319.kin_dom Protein Kinase Domain None 27 None Fasta, JSON
18319.NA RNA None 5984 None Fasta, JSON

Protein domain

Protein domains of 18319.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 18319.AA Ciliate-E1 915-1085 20 5.2e-18 55.53 In-house 1-202 (202) Show / Hide
Range on Protein: 915-1085
Range on HMM: 1-202/202
Sequence Identity: 20% (41 aa)

LDSDSEKFLRQIFKLGDHINSGGEADIFTNQN-NDNIVYRELQQQN-ILNIDSSH----LIEDKV-NHTKYIIYAIQKCQMSLYDEIL------------
. . |. .  ....  ...|.  .  | ...| |.|  . |..... |... .      .|. .     . .|  ...|..||.|..             
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMKFKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQCQ

-SKKVFSLRETLKFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYQLSDFGASQ-----QVNFIDPFCNFEMYTPGFKPQ------DRVKNLPFYHD
  .. |.  . .. |  ... || |.|. |.|.|||| |||. ...||...||| |.     | . .. ..  ..| |  . .      .. ..  .  |
QNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSD

IY
||
IY

Kinase 18319.AA Ciliate-B2 983-1050 36 1.6e-17 37.67 In-house 80-151 (197) Show / Hide
Range on Protein: 983-1050
Range on HMM: 80-151/197
Sequence Identity: 36% (26 aa)

IQKCQMSLYDEIL----SKKVFSLRETLKFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYQLSDFGAS
..||. || .|.      .| |     .. |   .  || .| . | | |||| |||.   .|| ..||| |
MEKCECSLKQELQKIQKQQKCFNNQKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGIS

Kinase 18319.AA Ciliate-C6 985-1054 36 1e-10 34.19 In-house 117-188 (306) Show / Hide
Range on Protein: 985-1054
Range on HMM: 117-188/306
Sequence Identity: 36% (26 aa)

KCQMSLYDEILSKKVFSLRETLKFISTAFHLLIVLRQ-KYIYHSDIKPGNILKIDD-NNYQLSDFGASQQVN
| .....     .. |.  | ..| .    .|  ..    | | |||| ||| .|| ||| |||||..|| .
KQEINIFSFNYKYEHFDENEIVQFCKQIGKTLADIYNECNIAHRDIKPSNILIMDDENNYYLSDFGCAQQLF

Kinase 18319.AA Ciliate-E3 1016-1052 48 5.5e-08 21.3 In-house 116-155 (202) Show / Hide
Range on Protein: 1016-1052
Range on HMM: 116-155/202
Sequence Identity: 48% (20 aa)

LIVLRQKYIYHSDIKPGNILKIDDNN----YQLSDFGASQQ
.| . .| | |||||| ||| .| ||     . .|||.| |
MIAIHEKNIIHSDIKPDNIL-VDKNNNQLIIKICDFGESKQ

Kinase 18319.AA S_TKc 927-1156 14 2.1e-07 -68.39 SMART 1-231 (231) Show / Hide
Range on Protein: 927-1156
Range on HMM: 1-231/231
Sequence Identity: 14% (39 aa)

FKLGDHINSGGEADIFTNQNND-----------NIVYRELQQQNILNIDSSHLIEDKVNHTKYIIYAIQKCQM---SLYDEILSKKV------FSLRETL
......| .|. .  .  ....           . ..||.|     . .    . |   . ...      |     .|.| | ...       |.  .. 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HAR

KFISTAFHLLIVLRQKYIYHSDIKPGNILKIDDNNYQLSDFGASQQVNFIDPFCNFEMYTPGFKPQDRVKNLPFYH---DIYSFGKTIQKLLIQQLENQT
...   .  |  . .. | | |.|| ||| .|. .  ..||| . |.       .    || . .   .   .. .   |..|.| ..  .|  .   . 
FYMYQICCALEYCHSHGIIHRDLKPENIL-LDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP-

EIYDCLNKFIKEICKDDENSINVDCFELPKKFINKIMKF------TNDEVIE----VFLEEYL
     ... .| |.            .  | ||.|....      |  |. .    . . ...
----QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 18319.AA Ciliate-A1 1024-1055 40 2.1e-07 21.21 In-house 122-153 (301) Show / Hide
Range on Protein: 1024-1055
Range on HMM: 122-153/301
Sequence Identity: 40% (13 aa)

IYHSDIKPGNILKIDDNNYQLSDFGASQQVNF
| |.|.||.|||  .|. . . |.| |.|  .
ILHRDLKPQNILIHFDDKWKICDLGMSKQLEQ

Kinase 18319.AA RAN 1024-1048 62 2.2e-05 13.89 In-house 170-195 (324) Show / Hide
Range on Protein: 1024-1048
Range on HMM: 170-195/324
Sequence Identity: 62% (17 aa)

IYHSDIKPGNILKID--DNNYQLSDFG
||| |||| ||| ||  | |  | |.|
IYHCDIKPENIL-IDGIDWNIYLCDWG

Kinase 18319.AA FRAY 1026-1050 56 2.7e-05 12.05 In-house 130-154 (277) Show / Hide
Range on Protein: 1026-1050
Range on HMM: 130-154/277
Sequence Identity: 56% (14 aa)

HSDIKPGNILKIDDNNYQLSDFGAS
| ||| ||||  .| . |..||| |
HRDIKAGNILIGEDGTIQIADFGVS

Kinase 18319.AA C8 1019-1053 46 4.4e-05 13.73 In-house 139-177 (226) Show / Hide
Range on Protein: 1019-1053
Range on HMM: 139-177/226
Sequence Identity: 46% (18 aa)

LRQKYIYHSDIKPGNILKIDDNNYQ----LSDFGASQQV
. .| | | |||| |.|   |.||     |.||| . ||
IHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQV

Kinase 18319.AA LKB 1024-1059 38 5.7e-05 10.76 In-house 125-160 (265) Show / Hide
Range on Protein: 1024-1059
Range on HMM: 125-160/265
Sequence Identity: 38% (14 aa)

IYHSDIKPGNILKIDDNNYQLSDFGASQQVNFIDPF
. | ||||||.|   ||   ..|||   |..   ..
VVHKDIKPGNLLLTHDNTLKICDFGVAEQLHHFQRD

Kinase 18319.AA Ciliate-E8 1024-1050 44 6e-05 11.41 In-house 110-138 (138) Show / Hide
Range on Protein: 1024-1050
Range on HMM: 110-138/138
Sequence Identity: 44% (13 aa)

IYHSDIKPGNIL-KI-DDNNYQLSDFGAS
| |.|.|  ||| .  || .  . ||| |
IIHCDFKLNNILVQRNDDTKIKIIDFGFS

Kinase 18319.AA Ciliate-B2 1069-1088 45 0.064212 0.18 In-house 178-197 (197) Show / Hide
Range on Protein: 1069-1088
Range on HMM: 178-197/197
Sequence Identity: 45% (9 aa)

FKPQDRVKNLPFYHDIYSFG
.. |  | |. |  |||| |
DHNQTFVTNIDFQSDIYSMG