Gene 22827 (Tetrahymena)

22827

Species: Tetrahymena
Alias: 22827, TTHERM_00937680, 1113, 169.m00067, PreTt22827
External Links: Tetrahymena Genome Database (TGD) ,
Annotation:

Classification

Group: Other
Family: Ciliate-C8
Subfamily: C8

Sequence

Name Sequence Type Origin Length Description Download
22827.AA Protein None 300 None Fasta, JSON
22827.kin_dom Protein Kinase Domain None 73 None Fasta, JSON
22827.NA RNA None 903 None Fasta, JSON

Protein domain

Protein domains of 22827.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 22827.AA C2 136-237 36 9.6e-44 147.34 In-house 1-104 (245) Show / Hide 
Range on Protein: 136-237
Range on HMM: 1-104/245
Sequence Identity: 36% (38 aa)

GSFALVIKAINKNSQKQVALKIVLCNQNESNEEESALKEYDLLKKIKHCPYLVDVYNQFYVYEEEIIIQDSDDEEQIAEKPK--NQNEKLKSFLVLELEF
|.|.||.||.||.....|||||. |..|. |.... .||| ...... .||...||| ||........ |.|..|...|...  .|....|.|.|.|.||
GAFGLVLKAFNKKQNRHVALKIQECQSNDINGMHEVQKEYGIMRQCQNMPYIIKVYNYFYLTVNKKEDEDEDNDEEEKEQENIKKQKNEKKIFVVYEQEF

CKSK
|...
CQGN
Kinase 22827.AA Ciliate-C8 136-259 26 1.4e-24 85.15 In-house 1-124 (238) Show / Hide 
Range on Protein: 136-259
Range on HMM: 1-124/238
Sequence Identity: 26% (35 aa)

GSFALVIKAINKNSQKQVALKIVLC-NQNESNEEESALKEYDLLKKIKHCPYLVDVYNQFYVYEEEIIIQDSDDEEQIAEKPK--NQNEKLKSFLVLELE
|.|..|.||.||.....||||.. | |... |..|.  ||| .. .   .|..|.||. ||. ||.   .|.......... |  .      || |.|.|
GAFGMVLKAQNKKQNRKVALKFRECVNKIQKNQMEHEIKEYEMIMQFCQMPFVVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKK------SFFVMEME

FCKSK-DYQTILYL--NFNKKFKRMIKFQL
.|... .... .    . .. ..  .|...
KCQQNCNLKQYFDRCRKKQSYPSQQMKEII
Kinase 22827.AA CMGC 127-195 16 3.1e-16 48.94 In-house 1-108 (513) Show / Hide 
Range on Protein: 127-195
Range on HMM: 1-108/513
Sequence Identity: 16% (18 aa)

YNDFEYLGNGSFALVIKAIN--------------KNSQKQVALKIVLCNQNESNEEE----------SALKEYDLLKKIK----------------HCPY
|   ...| |... | |...              ......||.|..  .. . ...           .|| |  .||...                | ..
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

LVDVYNQFY
.|  |. ||
IVKLYDIFY
Kinase 22827.AA C8 127-259 22 1.6e-14 46.91 In-house 1-128 (226) Show / Hide 
Range on Protein: 127-259
Range on HMM: 1-128/226
Sequence Identity: 22% (31 aa)

YNDFEYLGNGSFALVIKAINKNSQKQVALKIVLCNQN-ESNEEESALKEYDLLKKIKHCPYLVDVYNQFYVYEEEIIIQDSDDEEQIAEKPKNQNEKLKS
 |.|.|| .|....|.|| | .......||.  | .. . ...||  ||| ......    .| .|. ||  .|..  .. . |  .         . ||
FNNFQYLSFGAYGMVLKAKNVKDNREIVLKFQKCQNKQDIQNIESIMKEYEMPQVFQQYDFYVNEYDCFYEMYEVFEEEKCSNEKIVQ-------TEEKS

FLVLELEFCKSKDYQTILYLNFNKKF-KRMIKFQL
. | |.| |...  |  ...  ...  .  .|...
CFVMEMELCEQNLKQLYDERRNKQQQFSKEMKEII
Kinase 22827.AA STE20 127-188 29 6.1e-13 43.92 In-house 1-67 (288) Show / Hide 
Range on Protein: 127-188
Range on HMM: 1-67/288
Sequence Identity: 29% (20 aa)

YNDFEYLGNGSFALVIKAINKNSQKQ----VALKIVLCNQNES--NEEESALKEYDLLKKIKHCPYLV
|...| .|.||.  | ||..| ....    || |..  .. .   .|.|. .||.. .|. | .|. |
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK-HPNIV
Kinase 22827.AA Ciliate-E1 133-234 24 3.9e-12 36.22 In-house 1-116 (202) Show / Hide 
Range on Protein: 133-234
Range on HMM: 1-116/202
Sequence Identity: 24% (29 aa)

LGNGSFALVIKAINKNSQ-KQVALKIVLCNQN-ESNEEESALKEYD-LLKKIKHCPYLVDVYNQFYVYEE--EIIIQDSDDEEQIAEKP----------K
.|||||..|.||...|.. .|||.||..|..| ..|.... .|||. ..| .|   |.......... .   .|||... ...   .            .
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNHNRLEYWQQC

NQNEKLKSFLVLELEFC
.||..  .|. ..  ..
QQNQNQFTFQQKMQIIF
Kinase 22827.AA CDK 127-191 28 1.5e-11 33.08 In-house 1-73 (284) Show / Hide 
Range on Protein: 127-191
Range on HMM: 1-73/284
Sequence Identity: 28% (22 aa)

YNDFEYLGNGSFALVIKAINKNSQ-----KQVALKIVLCNQNESNEEE------SALKEYDLLKKIKHCPYLVDVY
|   | .| |... | ||..|...     . |||| .   ..   |||      .|. |  |||..  .|. | ..
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEG-REEEKEGFPITAIREISLLKEL--HPNIVKLH
Kinase 22827.AA STE 127-203 19 3.3e-11 35.95 In-house 1-114 (359) Show / Hide 
Range on Protein: 127-203
Range on HMM: 1-114/359
Sequence Identity: 19% (22 aa)

YNDFEYLGNGSFALVIKAINKN---------------SQKQVALKIVLCNQNES---------------NEEESALKEYDLLKKIKH-CPYLVDVYNQFY
. . | .|.|.|  | ||.|..               ... .| |..  .....               .|... ||| ...|| .| .|. |  |  ..
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

VY------EEEIII
.       ..|. |
KEGHNHKNDDELWI
Kinase 22827.AA CAMK 132-203 14 3.1e-10 28.45 In-house 1-134 (425) Show / Hide 
Range on Protein: 132-203
Range on HMM: 1-134/425
Sequence Identity: 14% (19 aa)

YLGNGSFALVIKAINKNSQ------------KQVALKIVLCNQNESNE--------------------------EESALKEYDLLKKIK------HCPYL
 || |||. | ..|.||..            ..|| ||.  ..  ...                          ... ..|....||..      . | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VDVYNQFY----------------VYEE---EIII
.  |  .                 |. .   ....
IKLYEVYEDPHYFKNTNDYETSKQVF-TKDKHMYM
Kinase 22827.AA CAMK1 127-183 23 3.6e-10 25.69 In-house 1-67 (276) Show / Hide 
Range on Protein: 127-183
Range on HMM: 1-67/276
Sequence Identity: 23% (16 aa)

YNDFEYLGNGSFALVIKAINKNS---QKQVALKIVL-CNQNESNEE---ESALKEYDLLKK---IKH
|. .. .|.|.|. | ....|..   .||.|.|.     . . ...   |. ..| . .||   |.|
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKCIDKKKFMKKKDMQKQEALENEIEIMKKVSKIDH
Kinase 22827.AA Pkinase 127-188 28 1.4e-09 35.0 Pfam 1-63 (293) Show / Hide 
Range on Protein: 127-188
Range on HMM: 1-63/293
Sequence Identity: 28% (18 aa)

YNDFEYLGNGSFALVIKAINKNSQKQVALKIVLCNQNESNEEESALK--EYDLLKKIKHCPYLV
|   . .| |||. | |...|...|.||.||.    ..|........  |  ..|.. ..|. |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRL-NHPNIV
Kinase 22827.AA S_TKc 127-295 13 0.000732 -120.28 SMART 1-231 (231) Show / Hide 
Range on Protein: 127-295
Range on HMM: 1-231/231
Sequence Identity: 13% (35 aa)

YNDFEYLGNGSFALVIKAINKNSQKQVALKIVLCNQNESNEEESALKEYDLLKKIKHCPYLVDVYNQFYVYEEEIIIQ----DS---DDEEQIAEKPKN-
|   . .| |.|. | |...|.....||.||.          |....| ..|||  |.|..|  |  |.   ... .     |    |  . | ..... 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----QNEKLKSFLVLE----LEFCKSK--------------------------------------------DYQT----------------ILYLNFNKK
     .|    |.. .    ||.| |.                                             | .                  |  |   
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQLTTFCGTPWYMAPEVLGYGKCKCDWWSCGCILYEMLCGYPPFP-Q

FKRMIKFQLFDNKRHFKLVNLKGLECLAQFQCPHSN----IWKLNE--------DII
 ..|.|  .             ... . .  .   .    . .. .          .
MQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF