Gene 7935 (Tetrahymena)

7935

Species: Tetrahymena
Alias: PreTt07935, 7935, 3735.m00073, 73.m00179, 325, TTHERM_00558380
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E2
Subfamily: Ciliate-E2-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
7935.AA Protein None 511 None Fasta, JSON
7935.kin_dom Protein Kinase Domain None 260 None Fasta, JSON
7935.NA RNA None 1536 None Fasta, JSON

Protein domain

Protein domains of 7935.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 7935.AA Ciliate-E2-Unclassified 13-272 26 3.3e-93 315.97 In-house 1-352 (352) Show / Hide 
Range on Protein: 13-272
Range on HMM: 1-352/352
Sequence Identity: 26% (95 aa)

YSESNELGSGAFAQVFKGINKQTNTDV-----AIKVISRQ-KLKKYGEEIINAIGDEVNILQKLSFLS----------QKDPCPFIVKIFDCFQTTNNIY
|     .|.|.|..|.| ..|...  .     ..|....  |.... . .|. . .|.|...| .. .          .  |.||||| |.|||...|||
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKK-YHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIY

IILEYCNGGNLLDIIKKCPQ----------------GIPEQQAI-----KIFYQIVSGI-NYIAKHDIVHRDLKPENIFIHDG----VYKIGDFGFAS--
|..|||.||.|...|||...                 ..||||.     ..|.||..|.  .. |..|.|||.|||||.....      || |||...  
IVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKY

-----------------QKNMFYTTLGTYPYM----APEFFKDPSYD----KLVDIWAVGIMYHEMLFNELYFMGNSQYE----------------VSQK
                 ...|..|. ||. ||    ||| ..   ||    . .|||..|.  .||||... | .|....                . |.
QQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQN

ICNVPYKIVRPNM------ISPNSQDVLI----KCIEKDRSVRITADQLINHPLF
|.. ....   .       .||. .| .     |...|. . |||..|..|||.|
IKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 7935.AA ULK 13-272 33 9.6e-89 301.13 In-house 1-324 (324) Show / Hide 
Range on Protein: 13-272
Range on HMM: 1-324/324
Sequence Identity: 33% (109 aa)

YSESNELGSGAFA-QVFKGINKQT---NTDVAIKVISRQKLKKYGEE-----IINAIGDEVNILQKLSFLSQKDPCPF--IVKIFDCFQTT--NNIYIIL
|. ...||.|.|. .|.||.||.|   | .||.|.|...|..|   |     ... .  |..|..||  |.    .|.  ||| .|.|.|.  ||||||.
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYVACKMIDKKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELK----HPNHHIVKLYDWFETSNHNNIYIIM

EYCNGGNLLDIIK---KCP-----QGIPEQQAIKIFYQIVSGINYIAKHDIVHRDLKPENIFIHDG-------------VYKIGDFGFASQKN-------
||||||.| ..||   |.|     . ..||.||..|.||..|  .. || |.|||.||.|| ||.|             |.||.||||| . .       
EYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQ

MFYTTL------GTYPYMAPEFFKDP----SYD-KLVDIWAVGIMYHEMLFNELYFMGNSQYEVSQK--------------ICNVPYKIVRPN---MISP
|..|..      ||  ||||. ...      |. . .||| .|....|||... .| ..  ..  ..              |.| | ..  |.    |||
MCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISP

NSQDVLIKCIEKDRSVRITADQLINHPLF
...| . .....|.. ||. ....|||.|
ECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase 7935.AA Ciliate-E2 13-272 25 1.5e-88 300.52 In-house 1-365 (365) Show / Hide 
Range on Protein: 13-272
Range on HMM: 1-365/365
Sequence Identity: 25% (96 aa)

YSESNELGSGAFAQVFKGINKQTNTDVAIKVISRQK----------------LKKYGEEIINAIGDEVNILQKLS----FLSQ------KDPCPFIVKIF
|   . .|.|.|..|.|. ..... ..|||.|  ||                .| . .  |..|  | .|....     .. .      .. .|.|.|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIID-QKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKI-NEKNILEQLNHPNIIKMY

DCFQ--TTNNIYIILEYCNGGNLLDIIK----KCPQGIP------EQQAIKIFYQIVS---------------GINYIAKHD-IVHRDLKPENIFIHDGV
.|||  ..||||...|||.||.|.|.||    |... |.      |.....|..||..               ...|. .   |.|||.|||||..    
ECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

YKIGDFGFAS-----------------------------------QKNMFYTTLGTYPYMAPEFFKDPS---------YDKLVDIWAVGIMYHEMLFNEL
 || |||..                                    | |||.|..||..||||| ..  .         ||. .|||..|.. .||||...
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

YFMGNSQYEVSQKICNVPYKIVRPNM----------------ISPNSQDVLIK----CIEKDRSVRIT-ADQLINHPLF
 |         |.|.. ....  |..                .|.. .| . |    ...|| . ||| ..|..||| |
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 7935.AA ULK 13-272 32 3.5e-84 286.0 In-house 1-329 (329) Show / Hide 
Range on Protein: 13-272
Range on HMM: 1-329/329
Sequence Identity: 32% (109 aa)

YSESNELGSGAFAQVFKGINKQT----NTDVAIKVISRQKLKKYGEE-----IINAIGDEVNILQKLSFLSQKDP------CPFIVKIFDCFQTT--NNI
|. ...||.|.|..|.||.||.|    | .||.|.|..||...   |     ... .  |. |..||     |.|      .| ||| .|.|.|.  |||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKL-----KSPNRHKNHHPNIVKLYDWFETSNHNNI

YIILEYCNGGNLLDIIK---KCP------QGIPEQQAIKIFYQIVSGINYIAKHDIVHRDLKPENIFIHDG-------------VYKIGDFGFASQKN--
|||.||||||.| ..||   |.|      . ..||.||..|.||..|  .. || |.|||.||.|| ||.|             |.||.||||| . .  
YIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDND

-----MFYTTL------GTYPYMAPEFFKDP----SYD-KLVDIWAVGIMYHEMLFNELYFMGNSQYEVS-----QK----------ICNVPYKIVRP--
     |..|..      ||  ||||. ...      |. . .||| .|....|||... .| ..  ..       .           |.. | ..  .  
NMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGN

-NMISPNSQDVLIKCIEKDRSVRITADQLINHPLF
 . |||...| . .....|.. ||. ..|.|||.|
DPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 7935.AA S_TKc 13-272 34 9.5e-84 285.45 SMART 1-231 (231) Show / Hide 
Range on Protein: 13-272
Range on HMM: 1-231/231
Sequence Identity: 34% (94 aa)

YSESNELGSGAFAQVFKGINKQTNTDVAIKVISRQKLKKYGEEIINAIGDEVNILQKLSFLSQKDPCPFIVKIFDCFQTTNNIYIILEYCNG--GNLLDI
|   ...|.|||..|.|...| |.  ||||.|.            . |  |..||.|         .|.|||..|.||. ...|...|||.|  |.|.|.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------------EHIRREIQILKK--------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDY

IKKCPQG-----IPEQQAIKIFYQIVSGINYIAKHDIVHRDLKPENIFIHDGVYKIGDFGFASQKNMFYTTLGTYPYMAPEFFKDPSYDK-LVDIWAVGI
|||.. .     .|| .| ...|||.....|. .| |.|||||||||.. . . ||.|||.| |    .|  ||  ||||| .   .|.|  .|.|..|.
IKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL---TTFCGTPWYMAPEVL---GYGKCKCDWWSCGC

MYHEMLFNELYFMGNSQYEVSQKICNVPYKIVRPNMISPNSQDVLIKCIEKDRSVRITADQLIN-------HPLF
.  |||  .  |    .... .||.            ||   | . || .|| . |.|| .. .       || |
ILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 7935.AA Pkinase 13-272 30 1e-74 259.31 Pfam 1-293 (293) Show / Hide 
Range on Protein: 13-272
Range on HMM: 1-293/293
Sequence Identity: 30% (91 aa)

YSESNELGSGAFAQVFKGINKQTNTDVAIKVISRQKLKK-YGEEIINAIGDEVNILQKLSFLSQKDPCPFIVKIFDCFQTTNNIYIILEYCNGG----NL
|     .|||.|..|.|...| |.  ||.|.|.... |.   .. ...   |. |...|.       .|.||...|.|.. ..||...|||.||     |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--SEIQIMKRLN-------HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDL

LDIIK-KCPQGI--PEQQAIKIFYQIVSGINYIAKHDIVHRDLKPENIFIH-DGVY----KIGDFGFASQ----KNMFYTTLGTYPYMAPEFFK-DPSYD
 |.|. .   ..  .|.......|||..|..|. .. |.|||||||||.|. .|.     ||.|||.| |    .  ..|  ||..|||||  . .. |.
FDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQYYG

KLVDIWAVGIMYHEMLFNELYFMGN------SQYEVSQKICNVPYKIVRPNMIS-------------------PNSQDVLIKCIEKDRSVRITADQLINH
. ||.|..|.. .|||. .. | |       .|... ..|   |..  .|. .|                   .. .|.. .|..|| . |.||.|. .|
PKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQH

PLF
| |
PWF
Kinase 7935.AA AGC 13-272 21 1.7e-74 191.15 In-house 1-395 (395) Show / Hide 
Range on Protein: 13-272
Range on HMM: 1-395/395
Sequence Identity: 21% (87 aa)

YSESNELGSGAFAQVFKGINK------QTNTDVAIKVISRQK---LKK--YGEEIINA--------IGDEVNILQKLS------FLSQKDPCPFIVK-IF
.     .| |.| .|.    |      .|.   |.||.. ..   .||    | ....        .  | |||.|..      .      .|||||  .
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPI-KS--HHPFIVKILH

DCFQTTNN--IYIILEYCN---------GG-NLLDIIKK--CPQGIPEQQAIKIFYQ-------IVSGINYIAK-HDIVHRD-LKPENIFIHD-GVYKIG
 .||. ..  .|...||..         ||  |. ....    .  .|..|  .. .       ||... |. . ..|.||| |||||| . . |  |. 
YSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLT

DFGFASQ------------------------------------------------------KNMFYTTLG--TYPYMAPEFFKDPSYDKLVDIWA--VGI
|||.. .                                                      ... .|  |  |  ||||| .    |.| .|.|.  .|.
DFGLCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGC

MYHEMLFNELYFMGNS----------QYEVSQKIC------NVPYKIVRP--------NMISPNSQDVLIKCIEKDRSVRIT----------ADQLINHP
.  |||.    | |..          ..|. |||.      | . |. .|          .||. .| . |...||.. |..          |... |||
LMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHP

LF
 |
WF
Kinase 7935.AA CAMK 18-272 21 2.5e-74 238.72 In-house 1-425 (425) Show / Hide 
Range on Protein: 18-272
Range on HMM: 1-425/425
Sequence Identity: 21% (94 aa)

ELGSGAFAQVFKGINKQTN------------TDVAIKVISRQKLKKY-----------------------GEEIINAIGDEVNILQKLS----FLSQKDP
.||.|.|..|...|.|.|.            . ||||.|...|||.                         ..    .  |..|..||.    .|.    
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLD----

CPFIVKIFDCFQ------------TTNN--------IYIIL---EYCNGG----NLLDIIKKCPQG--------------IPEQQAIKIFYQIVSGINYI
 | |.|... ..            | ..        .|...   ||| ||     |.| |.. ...              ..|..| ..| ||.|...|.
HPNIIKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYC

AKHDIVHRDLKPENIFI-HD-----------------GVYKIGDFGFASQKNM---------------------------FYTTLGTYPYMA-PEFFKD-
 .|.||||||||||| . ..                 .  || ||||| ...                            ..|  || .||| || ..  
HSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGK

-------------PSYDKLVDIWAVGIMYHEMLFNELYFMGN-------------SQYEVSQKICNVPYKIVRPNM--------------ISPN------
             | |.. .|.|..|..   ||  .. | |              ..||  .||..  |    | .              || .      
GHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVS

--SQDVLIKCIEKDRSVRITADQLINHPLF
   .| . |. ..| . |.|..|  ||| .
QECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 7935.AA Ciliate-B1 13-271 34 7.1e-66 225.17 In-house 1-290 (290) Show / Hide 
Range on Protein: 13-271
Range on HMM: 1-290/290
Sequence Identity: 34% (100 aa)

YSESNELGSGAFAQVFKGI---NKQTNTDVAIKVISRQKLKKYGEEIINAIGD-EVNILQKLSFLSQK-------DPCPFIVKIFDCFQTTNNIYIILEY
|.  |..|.||. |||.|    |.|..  ||.|.|. |..  ....  |     | .|.|.|..           .||. |. |.| .|.    ||| ||
YQQNNVIGQGAISQVFYGQFCQNQQCQQEVAVKKITKQTQ--DNDKQQNKYYQQELEIIQCLIKKMNNNKISCQSSPCDHICNIYDVIQCQQQYYIIMEY

CNGGNLLDIIKKCPQGIPEQQAIKIFYQIVSGINYIAKHDIVHRDLKPENIFIH-----------DGVY--KIGDFG-FASQKN-MFYTTLGTYPYMAPE
|..|.|.. | .| |    . .. .  ||..||.|  ||.|.|||||||||.||           ...|  ||.|||   .|.. |.  . ||  |||||
CEQGDLYNYIYNCHQNFTHDIVLDFCIQIAKGIQYLHKHKICHRDLKPENILIHKKNVPIYYNKQQNHYIFKITDFGISKMQQEYMMQSCVGTINYMAPE

FFK-DPSYDKLVDIWAVGIMYHEMLFNELYFM--GNSQYEVSQKICNVPYKIVRPNMISPNSQDVLI----KCIEKDRSVRITADQLINHPL
 ..   .||| ||||. |.  .| . ||..|   ||.| ||...| |  .   . . ..   | .      .| ..| . |||.||.|.  .
ILNFNQQYDKKVDIWSFGCIMYEIITNEQLFCSLGNTQQEVANQIRNFQCCDYQCHFQNNIYQEIQQLIQKYCLQPDPENRITIDQIIDRLM
Kinase 7935.AA CAMKL 13-272 29 8.5e-63 199.18 In-house 1-297 (297) Show / Hide 
Range on Protein: 13-272
Range on HMM: 1-297/297
Sequence Identity: 29% (92 aa)

YSESNELGSGAFAQVFKGIN-KQTNTDVAIKVISRQKLKKYGEEIINAIG----------DEVNILQKLS---FLSQKDPCPFIVKIFDCFQTTNN----
|    .|| |.|..|  ... . |.. ||||.| ..|...      | .|           |..|...|.           | |.|......| ..    
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKH-------PNIIKLYEVIETPEHDIET

--IYIILEYCNGGN--LLDIIKKCP---QGIPEQQAIKIFYQIVSGINYIAKHDIVHRDLKPENIFIH-DG--VYKIGDFGFASQ--------KNMFYTT
  ||...||| ||.  |.| |.| .   . .|| .| ..| ||||..||. .|.|||||.||||| .  .|  . || ||||. .         ... | 
KKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTF

LGTYPYMAPEFFKD--PSYD-KLVDIWAVGIMYHEMLFNELYFMGN--------SQYEVSQKICNVPYKIVRPNMISPNSQDVLIKCIEKDRSVRITADQ
 |..|||||| |..   .|| . ||||. |..   |.. .| | .          . .   ||    |..  .. .|   .| . |  ... . |.|..|
CGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQ

LINHPLF
. ||| .
IMNHPWM
Kinase 7935.AA STE 13-272 23 2.2e-57 196.98 In-house 1-359 (359) Show / Hide 
Range on Protein: 13-272
Range on HMM: 1-359/359
Sequence Identity: 23% (85 aa)

YSESNELGSGAFAQVFKGINK------QTNTD---------VAIKVISRQKLKKYGEE-------IINAIGDEVNILQKLSFLSQKDP-CPFIVKIFDCF
.    ..|.||| .|.|..|.      .|.           .|||... .. ...  |        .  . .. .||. ...... .. .|.||| ..|.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

QTT-------NNIYIILEYCNGGNLLDIIK---KCPQG----------IPEQQAIKIFYQIVSG-INYIAKHDIVHRDLKPENIFIHDGVYKIGDFGFAS
          ....|..||..|| | ||||   .|...          .||.| ..| .||. |  .|. .| |.|||.|| ||..     |. |||...
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCG

QKN--------------------MFYTTLGTYPYMAPEFFK------DPSYDKLVDIWAVGIMYHEMLFNELYFMGNSQYEVSQKIC-------------
| .                    . .|  ||  .||||  .      |. ||  .||| .|..  ||.  .  ..  .  ..   |              
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

---NVPYKIVR-----------------PNMISPNSQDVLIKCIEKDRSVRITADQLIN--HPLF
   . | ..                   |   ||. .| . || .|| . | ||.||..  || .
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 7935.AA Ciliate-E2c 13-272 28 6.1e-48 165.58 In-house 1-310 (310) Show / Hide 
Range on Protein: 13-272
Range on HMM: 1-310/310
Sequence Identity: 28% (90 aa)

YSESNELGSGAFAQVFKG---------INK-QTNTDVAIKVISRQKL--KKYGEEIIN-AIGDEVNILQKLSFLSQKDPCPFIVKIFDCFQTTNNIYIIL
... | |||| ...|.|.         ||. | |.  ||| .  . .  . . | .|  .|  |.|.. ..         | |.|. | .||...||.|.
IDRNNILGSGSYGKVYKAYYCEDYQNEINNVQMNQLFAIKMTCLKNKDIHMINEKDIKESIIREINMMKHMN-------HPHIIKFYDAKQTDKHIYLIM

EYCNGGNLLDIIKKCPQGIPEQQAIKIFYQIVSGINYIAKH-DIVHRDLKPENIFIHDGVYKIGDFGFA---SQKNMFYTT-----LGTYPYMAPEFFKD
||||||.|.. |.. |. . |.| .  | ||.|. .|. |   | |||.|||||.||.|. || ||||.      |  .|.      ||  ||||.  . 
EYCNGGTLEQYIYHKPK-PNEKQCLYYFSQIISAFKYLHKEKNIFHRDIKPENILIHNGMIKIADFGFSKICQDDNIQNTQGFNTCCGTPMYMAPQILEG

PSYDKL--VDIWAVGIMYHEMLFNELYFM------------------GNSQYEVSQKIC---------------NVPYKIVRP--NMISPNSQDVLIKCI
 ..  .   |||  |..  .||. .| .                   .|.. .  | |                . . .      ..||.  .. . | .
-KNYYTEKSDIWSLGVTLYYMLCYKLPWESIQEYDSHNICNHCYPWWQNTMKHLKQHIWEYFNPQASAAGVSPITQNIHFPENYEQNISQEVKQLIHKML

EKDRSVRITADQLINHPLF
..| . ||  |...||...
QVDEEKRIDWDEIFNHECI
Kinase 7935.AA TyrKc 13-272 20 9.9e-17 47.8 SMART 1-280 (280) Show / Hide 
Range on Protein: 13-272
Range on HMM: 1-280/280
Sequence Identity: 20% (63 aa)

YSESNELGSGAFAQVFKGINKQTNTDVAIKVISRQKLKKYGEEIINAIGDEVNILQKL--SFLSQKDPCPFIVKIFDCFQTT-------NNIYIILEYCN
 .   .||.||| .|.||. |   ..||.|..   .        . .. .| .|. ||  .        | ||... .  .          ..|..||. 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--------REDFMREARIMCKLGGH-------HPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMP

GGNLLDIIKKCPQGIPEQQAIKIFYQIVSGINYIAKHDIVHRDLKPENIFIHDGV-YKIGDFGFASQKNMF--------YTT-----LGT--YPY--MAP
.|.|.| ..|.   .. .. ... .|| .| .|.... ..||||   |. ....   ||.||| .              | .      |    |.  |||
HGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAP

EFFKDPSYDKLVDIWAVGIMYHEML-FNELYFMG-----NSQYEVSQKICNVPYKIVRPNM--------ISPNSQDVLIKCIEKDRSVRITADQLINHPL
| ...  .    |.|. |..  |.. . .    |      | .|| ...    |   .|           ..   ..  .| . | . | |  ..  | .
ECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYV-KQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HEC

F
|
F
Kinase 7935.AA Pkinase_Tyr 93-165 35 1.6e-12 43.03 Pfam 80-156 (270) Show / Hide 
Range on Protein: 93-165
Range on HMM: 80-156/270
Sequence Identity: 35% (27 aa)

NNIYIILEYCNGGNLLDIIKKC---PQGIPEQQAIKIFYQIVSGINYIAKHDIVHRDLKPENIFIH-DGVYKIGDFG
|.|||..||. .|.|||  .|    .| .. .. ... .|| .| .| . . ..||||   |. .. ..| ||.|||
NQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase 7935.AA Pkinase_Tyr 13-44 36 5e-06 21.07 Pfam 1-36 (270) Show / Hide 
Range on Protein: 13-44
Range on HMM: 1-36/270
Sequence Identity: 36% (13 aa)

YSESNELGSGAFAQVFKGINK----QTNTDVAIKVI
 .   .||.||| .|.||. |    .|...||.|..
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML