Gene 3011 (Tetrahymena)
3011
Group:
Other
Family:
Ciliate-E4
Sequence
Protein domains of 3011.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 3011.AA | Ciliate-E4 | 18-167 | 56 | 1e-109 | 364.55 | In-house | 1-150 (150) | Show / Hide |
Range on Protein: 18-167 Range on HMM: 1-150/150 Sequence Identity: 56% (85 aa) YRKIESVKDIHYGDIDIMESKDKKQIIAMKDRKFQNLEKLREQLGQIRKRRDNTHPNFIQVLEYFVMSEDNFCTSISRLIWTMEYIKKDLTVEIRQRKLQ |||||||||||||||.|||.|..||||.||.|||||..|.|.|..|.|.|.|..|.|.|.|.|||...||.||.||.||.|.|||..|||...|.|.|.| YRKIESVKDIHYGDIQIMEHKIQKQIIVMKIRKFQNETKARQQQQQFRRRQDLNHENIIMVYEYFHKKEDQFCSSIYRLYWFMEYLQKDLQQHIKQHKQQ QIPFDVSEIQQIAFASISAFANLQRDGIYFNDLRAQNILLTNSLEVKILD ...||.|||.||||..|.|...||...|...||...||.......|||.| GQHFDESEIWQIAFCCINAMYYLQQVNITHGDLKPSNIFFDQYFMVKIAD |
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| Kinase | 3011.AA | Ciliate-A5 | 28-288 | 23 | 1.2e-20 | 68.29 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 28-288 Range on HMM: 1-275/275 Sequence Identity: 23% (66 aa) HYGDIDIMESKDKKQIIAMKDRKFQNLEKLREQLGQIRKRRDNTHPNFIQVLEYFVMSEDNFCTSISRLIWTMEYIKKDLTVEIRQRKLQQ--IPFDVSE || . |. .. ..| ..| .. .| ||| .... . ... ||.. .... ||. .| |. .|| .| |... .| FYGCMKIWKNQHQQEYYICKQKQIQDEDRQKHFQQYFEQRMQLQHPNIVKLIDFHTHKKEEFCSQFYKVNCYYEYHDNNLEQEMQMRKQCQKDIFYNEQE IQQIAFASISAFANLQRDGIYFNDLRAQNILLTNSLEVKILDPV----------FEPNPPLLIQVLQTSKPKKGTYLAPNYLKFAKQK---NIPHKLTTH . |.. ||. . || .|. |.| |||.|| .||. | .... ... . ..| .||.| ... . . || . . LWYIMDCLISVCMYLQQNNICHGDIRPQNICLTQDGQVKLMDMNESKDFFYQINWSSYKQYQHHMSTENK----QYLSPMQWYQMMHRDEQNIQRPEHNW -KSESFSLGFVLMEACLLNEQ-DECFDFREGTINLE-NYKKNIQQIEDTYGEEISSMIKEMTNFNEKQRLDFIQLETKY ||. |.|| .. | |.. . . |. | . |. || |. |.|. . ||.| .|.| .| ||.|.. YKSDVFCLGMICLEMCTMRDCTQFYYDYETFQIQNNQLIKQLIQMKEKKYSEQFINFIKQMLQFEENKRPDFHQIYQYL |
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| Kinase | 3011.AA | S_TKc | 18-289 | 17 | 1.7e-07 | -66.95 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 18-289 Range on HMM: 1-231/231 Sequence Identity: 17% (52 aa) YRKIESVKDIHYGDIDIMESKDKKQIIAMKDRKFQNLEKLREQLGQIRKRRDNTHPNFIQVLEYFVMSEDNFCTSISRLIWTMEYIKK---DLTVEIRQR |.... . .| |. ..| |.| | |..| . .| ||| .. ...|. ..| |||. || |..| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK----HHPNIVKLYDVFQD---------DHLYMVMEYCDGDLGDLFDYIKKR KL--QQIPFDVSEIQQIAFASISAFANLQRDGIYFNDLRAQNILLTNSLEVKILD----PVFEPNPPLLIQVLQTSKPKKGT--YLAPNYLKFAKQKNIP . . ||. ... .. ..| . . . || || .||||.. ..|| | .. . || |.|| | GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------------TTFCGTPWYMAPEVL--------- HKLTTHKSESFSLGFVLMEACL---LNEQDECFDFREGTINLENYKKNIQQIEDTYGEEISSMIKEMTNFNEKQRLDFIQLET--------KYN . .. |. |.| .| | . . . ... |.| .| ..|. . ... ..|. .. . . -GYGKCKCDWWSCGCILYEMLCGYPPFP------------QMQMMFKKIG------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| MORN | 3011.AA | MORN | 786-807 | 45 | 8e-06 | 26.59 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 786-807 Range on HMM: 1-22/22 Sequence Identity: 45% (10 aa) SVYSGEKFKGKRHGNGKFLYAD ..| || ..|||||.|.. .|. DRYEGEWHNGKRHGHGVYWWAN |
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| MORN | 3011.AA | MORN | 788-810 | 43 | 1.2e-05 | 25.28 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 788-810 Range on HMM: 1-23/23 Sequence Identity: 43% (10 aa) YSGEKFKGKRHGNGKFLYADGGL |.|| .||.||.|.. ..||. YEGEWKNGKMHGHGVYTWPDGDR |
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| MORN | 3011.AA | MORN | 809-830 | 31 | 1.7e-05 | 25.49 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 809-830 Range on HMM: 1-22/22 Sequence Identity: 31% (7 aa) GLYEGSWFDGCMEGYGKLYYPS |||.|..| . |.|...... DRYEGEWHNGKRHGHGVYWWAN |
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| MORN | 3011.AA | MORN | 811-833 | 43 | 4.4e-05 | 23.2 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 811-833 Range on HMM: 1-23/23 Sequence Identity: 43% (10 aa) YEGSWFDGCMEGYGKLYYPSGKL |||.| .| |.|.|....|.| YEGEWKNGKMHGHGVYTWPDGDR |
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| MORN_2 | 3011.AA | MORN_2 | 820-841 | 45 | 0.000349 | 19.15 | Pfam | 1-22 (22) | Show / Hide |
Range on Protein: 820-841 Range on HMM: 1-22/22 Sequence Identity: 45% (10 aa) MEGYGKLYYPSGKLAYEGEWKR ..| | ||..|||.||...| LHGEWKWYYENGKLKYEINYKN |
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| MORN | 3011.AA | MORN | 833-854 | 40 | 0.000709 | 17.94 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 833-854 Range on HMM: 1-22/22 Sequence Identity: 40% (9 aa) LAYEGEWKRDKFTGQGVVYNDT |||||...|. |.|| . DRYEGEWHNGKRHGHGVYWWAN |
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| MORN | 3011.AA | MORN | 835-849 | 66 | 0.00079 | 18.66 | Pfam | 1-15 (23) | Show / Hide |
Range on Protein: 835-849 Range on HMM: 1-15/23 Sequence Identity: 66% (10 aa) YEGEWKRDKFTGQGV ||||||..|. |.|| YEGEWKNGKMHGHGV |
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| MORN | 3011.AA | MORN | 879-901 | 30 | 6e-06 | 26.33 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 879-901 Range on HMM: 1-23/23 Sequence Identity: 30% (7 aa) YEGGFLDDQKQGQGILYLSNGNR ||| . .....|.|... ..|.| YEGEWKNGKMHGHGVYTWPDGDR |
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| MORN | 3011.AA | MORN | 877-898 | 27 | 0.003067 | 13.18 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 877-898 Range on HMM: 1-22/22 Sequence Identity: 27% (6 aa) IQYEGGFLDDQKQGQGILYLSN ||| . .....|.|... .| DRYEGEWHNGKRHGHGVYWWAN |
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| MORN | 3011.AA | MORN | 902-924 | 21 | 3.88086 | 5.26 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 902-924 Range on HMM: 1-23/23 Sequence Identity: 21% (5 aa) FIGGFLNDMVEGIGIFVNQEGKE . | . |.. .| |... | YEGEWKNGKMHGHGVYTWPDGDR |
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