Gene 6544 (Tetrahymena)

6544

Species: Tetrahymena
Alias: TTHERM_00630300, 6544, 3831.m01438, PreTt06544, 983, 89.m00138
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-E6

Sequence

Name Sequence Type Origin Length Description Download
6544.AA Protein None 1724 None Fasta, JSON
6544.kin_dom Protein Kinase Domain None 65 None Fasta, JSON
6544.NA RNA None 5175 None Fasta, JSON

Protein domain

Protein domains of 6544.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
TPR_1 6544.AA TPR_1 84-117 41 6.4e-05 21.15 Pfam 1-34 (34) Show / Hide 
Range on Protein: 84-117
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

VQAIQNLALCNFYLKNYDEGILLMQKAIEMQPDY
..|  ||..| . ..|||| |   |||.|..|..
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 6544.AA TPR_2 84-117 32 9.3e-05 20.92 Pfam 1-34 (34) Show / Hide 
Range on Protein: 84-117
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

VQAIQNLALCNFYLKNYDEGILLMQKAIEMQPDY
. |  ||..| .....||| | ...||..  |..
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 6544.AA TPR 84-117 38 0.000248 21.64 SMART 1-34 (34) Show / Hide 
Range on Protein: 84-117
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

VQAIQNLALCNFYLKNYDEGILLMQKAIEMQPDY
..|  ||..| . ...||| |   |||.|..|..
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 6544.AA TPR_2 57-83 29 0.099662 10.2 Pfam 8-34 (34) Show / Hide 
Range on Protein: 57-83
Range on HMM: 8-34/34
Sequence Identity: 29% (8 aa)

AQQLFNQNDYKTAQIYFNQIVQEDSKN
.| ...|.||. |  |... .. | .|
GQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 6544.AA TPR 50-83 14 0.693935 1.98 SMART 1-34 (34) Show / Hide 
Range on Protein: 50-83
Range on HMM: 1-34/34
Sequence Identity: 14% (5 aa)

EQNILEKAQQLFNQNDYKTAQIYFNQIVQEDSKN
 .  . ... .....||. |  .... .. | .|
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 6544.AA TPR_1 56-83 10 3.899765 4.46 Pfam 7-34 (34) Show / Hide 
Range on Protein: 56-83
Range on HMM: 7-34/34
Sequence Identity: 10% (3 aa)

KAQQLFNQNDYKTAQIYFNQIVQEDSKN
... ......|. |  .... .. . .|
LGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 6544.AA TPR_2 187-220 35 9.2e-09 35.1 Pfam 1-34 (34) Show / Hide 
Range on Protein: 187-220
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

QKAHFQMGETHFKMQNYKDASEAYKKACKINPEN
 .|....|. ..|...|..| |.|.|| |..|.|
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 6544.AA TPR_1 188-220 42 1.2e-08 34.21 Pfam 2-34 (34) Show / Hide 
Range on Protein: 188-220
Range on HMM: 2-34/34
Sequence Identity: 42% (14 aa)

KAHFQMGETHFKMQNYKDASEAYKKACKINPEN
.|....| ...||.||..| |.|.|| ..||.|
EAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 6544.AA TPR 187-220 35 1.8e-07 32.08 SMART 1-34 (34) Show / Hide 
Range on Protein: 187-220
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

QKAHFQMGETHFKMQNYKDASEAYKKACKINPEN
 .|....|. ..|| .|..| |.|.|| ...|.|
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 6544.AA TPR_1 221-254 32 0.000272 18.97 Pfam 1-34 (34) Show / Hide 
Range on Protein: 221-254
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

YYFYLKLGTSQYKEQNLEEALKSLQQAVVLNNKF
.  .  ||  .|| .|..||.. .|.|. || ..
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 6544.AA TPR_2 221-254 23 0.000321 19.02 Pfam 1-34 (34) Show / Hide 
Range on Protein: 221-254
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

YYFYLKLGTSQYKEQNLEEALKSLQQAVVLNNKF
 . .  || . || ....||.. ...|. |. ..
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 6544.AA TPR 221-254 26 0.000365 21.08 SMART 1-34 (34) Show / Hide 
Range on Protein: 221-254
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

YYFYLKLGTSQYKEQNLEEALKSLQQAVVLNNKF
.  .. || . ||  ...||.. .|.|. |. ..
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 6544.AA TPR_1 119-152 29 0.00135 16.54 Pfam 1-34 (34) Show / Hide 
Range on Protein: 119-152
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

DKLYYYLGCAYCDQKHYMQGLVYLEKAMTQNQNN
 . .| || .|  .. | . . ...||   | ||
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 6544.AA TPR 119-152 26 0.006302 16.97 SMART 1-34 (34) Show / Hide 
Range on Protein: 119-152
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

DKLYYYLGCAYCDQKHYMQGLVYLEKAMTQNQNN
 . .| || .|  .. | . . ...||.. . ||
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 6544.AA TPR_2 119-152 35 0.007674 14.14 Pfam 1-34 (34) Show / Hide 
Range on Protein: 119-152
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

DKLYYYLGCAYCDQKHYMQGLVYLEKAMTQNQNN
 ...|.||..|  |..| . . |.|||   . ||
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 6544.AA TPR_2 153-186 29 0.025083 12.32 Pfam 1-34 (34) Show / Hide 
Range on Protein: 153-186
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

QDAIFMLGNTYQNISCLQIAQNYYKKLIEIDSSN
 .| ..||. | .   .. | .||.|....|  |
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 6544.AA TPR_1 154-186 30 0.104296 9.95 Pfam 2-34 (34) Show / Hide 
Range on Protein: 154-186
Range on HMM: 2-34/34
Sequence Identity: 30% (10 aa)

DAIFMLGNTYQNISCLQIAQNYYKKLIEIDSSN
.| . |||.| .   .. |  .|.| .|.. .|
EAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 6544.AA TPR 153-186 32 0.143335 8.0 SMART 1-34 (34) Show / Hide 
Range on Protein: 153-186
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

QDAIFMLGNTYQNISCLQIAQNYYKKLIEIDSSN
 .| . ||| | .   .. | ..|.| .|.| .|
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_3 6544.AA TPR_3 198-220 20 1.245475 5.68 Pfam 14-38 (38) Show / Hide 
Range on Protein: 198-220
Range on HMM: 14-38/38
Sequence Identity: 20% (5 aa)

FKMQNYKDASEA--YKKACKINPEN
. ...| .| ..  |. .|.. ..|
YMKKKYQQAYHLYQYHFLCIYDHWN
TPR_3 6544.AA TPR_3 153-186 21 43.156534 0.43 Pfam 1-38 (38) Show / Hide 
Range on Protein: 153-186
Range on HMM: 1-38/38
Sequence Identity: 21% (8 aa)

QDAIFML--GNTYQNISCLQIAQNY--YKKLIEIDSSN
 | .. .  . |...   .| | ..  |. | ..|. |
MDYWYSYWLAYTFYMKKKYQQAYHLYQYHFLCIYDHWN
TPR_2 6544.AA TPR_2 326-359 32 0.000188 19.84 Pfam 1-34 (34) Show / Hide 
Range on Protein: 326-359
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

LDGIKALGKLYFETNEFDQAIKVFEKGLLIDQNE
 ..  .||..|.. ...|.||. .|| | .| | 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 6544.AA TPR_1 326-359 26 0.000214 19.33 Pfam 1-34 (34) Show / Hide 
Range on Protein: 326-359
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

LDGIKALGKLYFETNEFDQAIKVFEKGLLIDQNE
 .  . || .|.. ...|.||. ..| | .. | 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 6544.AA TPR 326-359 29 0.000309 21.32 SMART 1-34 (34) Show / Hide 
Range on Protein: 326-359
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

LDGIKALGKLYFETNEFDQAIKVFEKGLLIDQNE
 .  . || .|.  ...|.||. ..| | .| | 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 6544.AA TPR_2 292-325 23 0.002674 15.76 Pfam 1-34 (34) Show / Hide 
Range on Protein: 292-325
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

ASSYFVLGDICIQEKQIQTAKLFFEESVKLDASF
|  .. ||..... .. . |. ..|...|||  .
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 6544.AA TPR_2 360-390 29 0.005507 14.65 Pfam 1-31 (34) Show / Hide 
Range on Protein: 360-390
Range on HMM: 1-31/34
Sequence Identity: 29% (9 aa)

VDIIYDIGCCLFELDKIQEATEQFRKAFRLN
... | .|.|.... . .|| | ..|| .|.
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLD
TPR_1 6544.AA TPR_1 360-390 32 0.005575 14.39 Pfam 1-31 (34) Show / Hide 
Range on Protein: 360-390
Range on HMM: 1-31/34
Sequence Identity: 32% (10 aa)

VDIIYDIGCCLFELDKIQEATEQFRKAFRLN
... | .| |.... . .|| | ..|| .||
AEAWYNLGNCYYKMGNYDEAIECYQKALELN
TPR_1 6544.AA TPR_1 292-325 14 0.009024 13.66 Pfam 1-34 (34) Show / Hide 
Range on Protein: 292-325
Range on HMM: 1-34/34
Sequence Identity: 14% (5 aa)

ASSYFVLGDICIQEKQIQTAKLFFEESVKLDASF
|  .. || .. . .. . |  .... ..|. ..
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 6544.AA TPR 360-393 26 0.021792 15.18 SMART 1-34 (34) Show / Hide 
Range on Protein: 360-393
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

VDIIYDIGCCLFELDKIQEATEQFRKAFRLNTIS
... | .| |.. . ...|| | ..|| .|.   
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR 6544.AA TPR 292-325 17 0.026863 14.39 SMART 1-34 (34) Show / Hide 
Range on Protein: 292-325
Range on HMM: 1-34/34
Sequence Identity: 17% (6 aa)

ASSYFVLGDICIQEKQIQTAKLFFEESVKLDASF
|  .. || .. . .... |  .......|| ..
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR 6544.AA TPR 258-291 23 0.053795 11.74 SMART 1-34 (34) Show / Hide 
Range on Protein: 258-291
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

GSIFYKLIEALVEQNHLEKCIQYYLKMFALNPKN
  ..| | ...  .. ....|..| |  .|.|.|
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 6544.AA TPR_1 258-291 26 0.0745 10.46 Pfam 1-34 (34) Show / Hide 
Range on Protein: 258-291
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

GSIFYKLIEALVEQNHLEKCIQYYLKMFALNPKN
  ..| |  .. ... ... |..| |  .|||.|
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 6544.AA TPR_2 266-291 30 0.098373 10.22 Pfam 9-34 (34) Show / Hide 
Range on Protein: 266-291
Range on HMM: 9-34/34
Sequence Identity: 30% (8 aa)

EALVEQNHLEKCIQYYLKMFALNPKN
... .|..... |.|| |  .|.|.|
QCYYKQGDYDEAIEYYEKALKLDPNN
TPR_3 6544.AA TPR_3 326-350 10 0.174377 8.59 Pfam 1-29 (38) Show / Hide 
Range on Protein: 326-350
Range on HMM: 1-29/38
Sequence Identity: 10% (3 aa)

LDGIKAL--GKLYFETNEFDQAIKV--FE
.| ....  .  ...  ...||...  ..
MDYWYSYWLAYTFYMKKKYQQAYHLYQYH
TPR_3 6544.AA TPR_3 360-379 22 53.911299 0.1 Pfam 1-22 (38) Show / Hide 
Range on Protein: 360-379
Range on HMM: 1-22/38
Sequence Identity: 22% (5 aa)

VDIIYDI--GCCLFELDKIQEA
.| .|.   .. ... .|.|.|
MDYWYSYWLAYTFYMKKKYQQA
TPR_2 6544.AA TPR_2 433-466 41 3.2e-09 36.73 Pfam 1-34 (34) Show / Hide 
Range on Protein: 433-466
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

AEAFYQKGLLYECTCNLEKAKEHFEKALQIYPQN
||| |. |..|.   ....|.|..||||...|.|
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 6544.AA TPR 433-466 38 3.5e-09 37.76 SMART 1-34 (34) Show / Hide 
Range on Protein: 433-466
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

AEAFYQKGLLYECTCNLEKAKEHFEKALQIYPQN
|||.|..|..|.   ....| |...|||.. |.|
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 6544.AA TPR_1 433-466 41 3.6e-09 35.98 Pfam 1-34 (34) Show / Hide 
Range on Protein: 433-466
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

AEAFYQKGLLYECTCNLEKAKEHFEKALQIYPQN
|||.|..|..|.   |...| |...|||.. |.|
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_1 6544.AA TPR_1 407-432 23 12.366445 2.71 Pfam 9-34 (34) Show / Hide 
Range on Protein: 407-432
Range on HMM: 9-34/34
Sequence Identity: 23% (6 aa)

QLQKSKENIKYSLEYFNFAILINSNN
... ...| .  .|... |. .| ||
NCYYKMGNYDEAIECYQKALELNPNN
TPR 6544.AA TPR 596-629 44 2.4e-07 31.63 SMART 1-34 (34) Show / Hide 
Range on Protein: 596-629
Range on HMM: 1-34/34
Sequence Identity: 44% (15 aa)

PYAYENLAACYYEKKQYQESIQFYQKALEYNKVD
. |. ||. ||| ...|.| |..|||||| .  .
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 6544.AA TPR_1 596-629 47 5.2e-07 28.47 Pfam 1-34 (34) Show / Hide 
Range on Protein: 596-629
Range on HMM: 1-34/34
Sequence Identity: 47% (16 aa)

PYAYENLAACYYEKKQYQESIQFYQKALEYNKVD
. |. ||..|||....|.| |..|||||| |  .
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 6544.AA TPR_2 528-561 35 2e-06 26.59 Pfam 1-34 (34) Show / Hide 
Range on Protein: 528-561
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

PKVNEMLGYSYEQIGENEKASQHYMKALQLNPND
...  .|| .|.. |. ..| ..| |||.|.||.
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 6544.AA TPR_1 534-561 46 2e-06 26.59 Pfam 7-34 (34) Show / Hide 
Range on Protein: 534-561
Range on HMM: 7-34/34
Sequence Identity: 46% (13 aa)

LGYSYEQIGENEKASQHYMKALQLNPND
||. |.. |. ..| ..| |||.||||.
LGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 6544.AA TPR_2 596-626 41 3e-06 26.24 Pfam 1-31 (34) Show / Hide 
Range on Protein: 596-626
Range on HMM: 1-31/34
Sequence Identity: 41% (13 aa)

PYAYENLAACYYEKKQYQESIQFYQKALEYN
..|. ||. |||....|.| |..|.|||...
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLD
TPR 6544.AA TPR 528-561 35 9e-06 26.45 SMART 1-34 (34) Show / Hide 
Range on Protein: 528-561
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

PKVNEMLGYSYEQIGENEKASQHYMKALQLNPND
...   || .|.. |. ..| ..| |||.|.||.
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 6544.AA TPR_2 562-595 38 1.6e-05 23.64 Pfam 1-34 (34) Show / Hide 
Range on Protein: 562-595
Range on HMM: 1-34/34
Sequence Identity: 38% (13 aa)

QTLLFNLGNCLFNLEKYDEAIEKYNILIHLNQNK
  ...|||.|......|||||| |. .. |. | 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 6544.AA TPR 630-663 35 3.6e-05 24.42 SMART 1-34 (34) Show / Hide 
Range on Protein: 630-663
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

PLTNYGLGKAFYSNNQYEEALKCFQITLSADHEN
. . | || ..|....|.||..|.|  |. | .|
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 6544.AA TPR_2 630-663 29 4.3e-05 22.1 Pfam 1-34 (34) Show / Hide 
Range on Protein: 630-663
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

PLTNYGLGKAFYSNNQYEEALKCFQITLSADHEN
.   | ||.. | ...|.||.....  |. | .|
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 6544.AA TPR_1 630-663 32 4.3e-05 21.77 Pfam 1-34 (34) Show / Hide 
Range on Protein: 630-663
Range on HMM: 1-34/34
Sequence Identity: 32% (11 aa)

PLTNYGLGKAFYSNNQYEEALKCFQITLSADHEN
. . | || ..|. ..|.||..|.|  |. . .|
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_1 6544.AA TPR_1 565-595 48 0.000181 19.59 Pfam 4-34 (34) Show / Hide 
Range on Protein: 565-595
Range on HMM: 4-34/34
Sequence Identity: 48% (15 aa)

LFNLGNCLFNLEKYDEAIEKYNILIHLNQNK
..|||||......|||||| |.  . || | 
WYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 6544.AA TPR 562-595 41 0.000233 21.73 SMART 1-34 (34) Show / Hide 
Range on Protein: 562-595
Range on HMM: 1-34/34
Sequence Identity: 41% (14 aa)

QTLLFNLGNCLFNLEKYDEAIEKYNILIHLNQNK
   ..|||||......|||||| |.  . |. | 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_3 6544.AA TPR_3 634-663 26 0.003195 14.51 Pfam 5-38 (38) Show / Hide 
Range on Protein: 634-663
Range on HMM: 5-38/38
Sequence Identity: 26% (9 aa)

YGL--GKAFYSNNQYEEALKCFQ--ITLSADHEN
|..  . .||.  .|..|.. .|       ||.|
YSYWLAYTFYMKKKYQQAYHLYQYHFLCIYDHWN
TPR_3 6544.AA TPR_3 602-629 28 0.356875 7.53 Pfam 7-38 (38) Show / Hide 
Range on Protein: 602-629
Range on HMM: 7-38/38
Sequence Identity: 28% (9 aa)

L--AACYYEKKQYQESIQFYQ--KALEYNKVD
.  |. .|.||.||. ...||   . .| . .
YWLAYTFYMKKKYQQAYHLYQYHFLCIYDHWN
TPR 6544.AA TPR 494-527 17 0.459944 3.55 SMART 1-34 (34) Show / Hide 
Range on Protein: 494-527
Range on HMM: 1-34/34
Sequence Identity: 17% (6 aa)

CKELIKEAKQLFTNKEYQKCIEVLQKISSVSDNF
 . .   .  .. ...|...|| .||  ..  |.
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 6544.AA TPR_2 494-527 14 3.83643 4.59 Pfam 1-34 (34) Show / Hide 
Range on Protein: 494-527
Range on HMM: 1-34/34
Sequence Identity: 14% (5 aa)

CKELIKEAKQLFTNKEYQKCIEVLQKISSVSDNF
 . .   .. .. ...|.. || ..|  .   |.
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_3 6544.AA TPR_3 565-595 14 28.024099 1.07 Pfam 4-38 (38) Show / Hide 
Range on Protein: 565-595
Range on HMM: 4-38/38
Sequence Identity: 14% (5 aa)

LFNL--GNCLFNLEKYDEAIEK--YNILIHLNQNK
.. .  .  ... .||..|..   |  |  .  ..
WYSYWLAYTFYMKKKYQQAYHLYQYHFLCIYDHWN
TPR 6544.AA TPR 699-732 26 6.7e-05 23.52 SMART 1-34 (34) Show / Hide 
Range on Protein: 699-732
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

SRMLSLMAGVLYEMKQYQKSIEKCEQAINLDSKN
.. .. .. ..| |..|.. || ...|. || .|
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 6544.AA TPR_1 699-732 23 0.000251 19.09 Pfam 1-34 (34) Show / Hide 
Range on Protein: 699-732
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

SRMLSLMAGVLYEMKQYQKSIEKCEQAINLDSKN
.. .. .. ..|.|..|.. || ...|. |. .|
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 6544.AA TPR_2 699-732 26 0.000262 19.33 Pfam 1-34 (34) Show / Hide 
Range on Protein: 699-732
Range on HMM: 1-34/34
Sequence Identity: 26% (9 aa)

SRMLSLMAGVLYEMKQYQKSIEKCEQAINLDSKN
 . . ... ..|....|.. || .|.|. || .|
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_2 6544.AA TPR_2 733-766 20 0.000464 18.45 Pfam 1-34 (34) Show / Hide 
Range on Protein: 733-766
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

FNAYLIKAASLKELCDFVHSLNQFEEAIKINPND
. |.   . .. .. |.   .. .|.|.|..||.
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_1 6544.AA TPR_1 733-766 14 0.000958 17.06 Pfam 1-34 (34) Show / Hide 
Range on Protein: 733-766
Range on HMM: 1-34/34
Sequence Identity: 14% (5 aa)

FNAYLIKAASLKELCDFVHSLNQFEEAIKINPND
 .|.  ... . .. ..   .  ...|...|||.
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR 6544.AA TPR 733-766 14 0.002244 18.46 SMART 1-34 (34) Show / Hide 
Range on Protein: 733-766
Range on HMM: 1-34/34
Sequence Identity: 14% (5 aa)

FNAYLIKAASLKELCDFVHSLNQFEEAIKINPND
  |.. .. ..  . |.   .. ...|....||.
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR 6544.AA TPR 767-800 20 0.196293 6.8 SMART 1-34 (34) Show / Hide 
Range on Protein: 767-800
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

PDCYYFYGQTLEAANLHMKALEKYDKSIMLASQT
....|  |. ... . . .|.| |.|.. |. . 
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 6544.AA TPR_2 767-800 23 0.40116 8.06 Pfam 1-34 (34) Show / Hide 
Range on Protein: 767-800
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

PDCYYFYGQTLEAANLHMKALEKYDKSIMLASQT
....|  || ..... . .|.| |.|.. |. . 
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR_3 6544.AA TPR_3 704-732 25 2.067227 4.93 Pfam 9-38 (38) Show / Hide 
Range on Protein: 704-732
Range on HMM: 9-38/38
Sequence Identity: 25% (8 aa)

LMAGVLYEMKQYQKSIEK--CEQAINLDSKN
| | ..|..|.||. ..    ... ..|..|
L-AYTFYMKKKYQQAYHLYQYHFLCIYDHWN
TPR_1 6544.AA TPR_1 767-800 20 8.952125 3.2 Pfam 1-34 (34) Show / Hide 
Range on Protein: 767-800
Range on HMM: 1-34/34
Sequence Identity: 20% (7 aa)

PDCYYFYGQTLEAANLHMKALEKYDKSIMLASQT
.. .|  |..... . . .|.| |.| . |  . 
AEAWYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_1 6544.AA TPR_1 865-890 46 8.1e-05 20.81 Pfam 1-26 (34) Show / Hide 
Range on Protein: 865-890
Range on HMM: 1-26/34
Sequence Identity: 46% (12 aa)

YAAIYNMGLCYKNIQKINDAIECFQK
. | ||.|.|| . .. ..||||.||
AEAWYNLGNCYYKMGNYDEAIECYQK
TPR_2 6544.AA TPR_2 831-864 23 0.001324 16.84 Pfam 1-34 (34) Show / Hide 
Range on Protein: 831-864
Range on HMM: 1-34/34
Sequence Identity: 23% (8 aa)

QNYFNEIGNNLFEKNDFHGAIECYKQELRYNSND
  . . .|. .....|.  |||.|.. |... |.
AEAWYNLGQCYYKQGDYDEAIEYYEKALKLDPNN
TPR 6544.AA TPR 865-898 35 0.009752 16.34 SMART 1-34 (34) Show / Hide 
Range on Protein: 865-898
Range on HMM: 1-34/34
Sequence Identity: 35% (12 aa)

YAAIYNMGLCYKNIQKINDAIECFQKNIINKHRE
. | ||.|.|| .  ....||||.|| .      
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_2 6544.AA TPR_2 865-890 38 0.021597 12.55 Pfam 1-26 (34) Show / Hide 
Range on Protein: 865-890
Range on HMM: 1-26/34
Sequence Identity: 38% (10 aa)

YAAIYNMGLCYKNIQKINDAIECFQK
 .| ||.|.|| . ..  .|||...|
AEAWYNLGQCYYKQGDYDEAIEYYEK
TPR 6544.AA TPR 831-864 29 0.080748 10.19 SMART 1-34 (34) Show / Hide 
Range on Protein: 831-864
Range on HMM: 1-34/34
Sequence Identity: 29% (10 aa)

QNYFNEIGNNLFEKNDFHGAIECYKQELRYNSND
  ... .|| .. ..|.  |||||.. |. . |.
AEAWYNLGNCYYKMGDYDEAIECYQKALELDPNN
TPR_1 6544.AA TPR_1 834-864 32 0.341939 8.15 Pfam 4-34 (34) Show / Hide 
Range on Protein: 834-864
Range on HMM: 4-34/34
Sequence Identity: 32% (10 aa)

FNEIGNNLFEKNDFHGAIECYKQELRYNSND
.. .|| .......  |||||.. |. | |.
WYNLGNCYYKMGNYDEAIECYQKALELNPNN
TPR_2 6544.AA TPR_2 809-830 13 39.873255 0.99 Pfam 13-34 (34) Show / Hide 
Range on Protein: 809-830
Range on HMM: 13-34/34
Sequence Identity: 13% (3 aa)

NLKQFQAAKQCMENVMIRYPQF
...... |....| .   .|..
KQGDYDEAIEYYEKALKLDPNN
Kinase 6544.AA Ciliate-E6 1242-1306 28 1.7e-31 97.62 In-house 73-154 (154) Show / Hide 
Range on Protein: 1242-1306
Range on HMM: 73-154/154
Sequence Identity: 28% (23 aa)

NIVHADIKPQNIFYDNQ-RAQIADFG--SCIVSNTQNNEYTP-------TFCSP-------ESESFESGQRITTSSDIYSLG
|.|.  |...|||.|.. ...|.|||  .||..|.|..|...       ..|.|       ...|.......|...||.|..
NYVLQNITLKNIFLDKNMNIKICDFGFQQCIIPNQQTKEFMAQKNQNKYHYCPPEQFDYSKDQQSKHYKVNWTQEGDIWSVC
Kinase 6544.AA Ciliate-B2 1222-1306 37 3.8e-18 39.17 In-house 104-197 (197) Show / Hide 
Range on Protein: 1222-1306
Range on HMM: 104-197/197
Sequence Identity: 37% (35 aa)

QQFLSIMLDCCEGLQQLTFYNIVHADIKPQNI-FYDNQRAQIADFG-SCIVSNTQNNE---YTPTFCSPES-ESF---ESGQRITTSSDIYSLG
| .. .. .  .|| |. .|||.| ||||||| |  |      ||| |.| .. |. .    |  . |||  | .    .  .|   |||||.|
QKLYQMIFQLIDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFGISSIKKDNQQIKIKGFTKKYASPEQMECDHNQTFVTNIDFQSDIYSMG
Kinase 6544.AA Ciliate-E1 1218-1303 35 2e-15 47.0 In-house 105-202 (202) Show / Hide 
Range on Protein: 1218-1303
Range on HMM: 105-202/202
Sequence Identity: 35% (35 aa)

QLTYQQFLSIMLDCCEGLQQLTFYNIVHADIKPQNIFYDNQ-RAQIADFGSCI------VSNTQNNEYTPTFCSPESES-----FESGQRITTSSDIY
|.| ||...|. .  .||..|  ||| | ||||||| ..|| . ...||| .        ...| . ||  ...||         .  | |.  ||||
QFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQEHNKNQKINYKSDIY
Kinase 6544.AA Ciliate-E2 1242-1306 21 9.5e-12 36.59 In-house 181-283 (365) Show / Hide 
Range on Protein: 1242-1306
Range on HMM: 181-283/365
Sequence Identity: 21% (23 aa)

NIVHADIKPQNIFYDNQRAQIADFGSCIVSNTQNNEY------------------------------------TPTFCSPESESFES------GQRITTS
||.| ||||.||..      |.||| .   ...|...                                    || . .||  . ..      ... ...
NIIHRDIKPENILF----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYK

SDIYSLG
.||.|||
CDIWSLG
Kinase 6544.AA Ciliate-E2-Unclassified 1218-1306 26 4.5e-11 34.66 In-house 134-257 (352) Show / Hide 
Range on Protein: 1218-1306
Range on HMM: 134-257/352
Sequence Identity: 26% (33 aa)

QLTYQQFL-----SIMLDCCEGLQQLTFYN-IVHADIKPQNIFYDNQ----RAQIADFGSCIVSNTQNNEY--------------TPTFC----------
..| || .      ..   ..||..|   | |.| ||||.||..||.    .  |.|||... ....||..              . |||          
IFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYT

SPESESFESGQRIT-TSSDIYSLG
.||    .     .  ..||.|||
APEVLQGQNYDHSKAYKCDIWSLG
Kinase 6544.AA CAMKK 1226-1287 26 7.3e-11 30.26 In-house 180-281 (396) Show / Hide 
Range on Protein: 1226-1287
Range on HMM: 180-281/396
Sequence Identity: 26% (27 aa)

SIMLDCCEGLQQLT-FYN-------------------IVHADIKPQNI-FYDNQ---RAQIADFG-SCIVS----NTQN-----------NEYTPTFCSP
....||. ||. |  . .                   |.| ||||||| . ..    .. ||||| |.|..    . .|           .. ||.|  |
KYFRDCIKGLEYLHNYQKACSYIIIYINEFIIDHFQDIIHRDIKPQNILIDEEGCGEHVKIADFGVSHIFEGQDQTLSNCESCFQRELNKTAGTPAFMAP

ES
|.
EL
Kinase 6544.AA CAMKK-Unclassified 1222-1287 29 1.7e-10 30.1 In-house 178-276 (392) Show / Hide 
Range on Protein: 1222-1287
Range on HMM: 178-276/392
Sequence Identity: 29% (29 aa)

QQFLSIMLDCCEGLQQLTFYN---------------------IVHADIKPQNI-FYDNQR-----AQIADFG-SCIVS---NT--QNNEYTPTFCSPES
|. ......|| ||| .  .|                     |.| ||||||| . .. .     . ||||| | |..    .  .||. |..| .||.
QYLKKYFRQCCKGLQYMHNFNQACSYIIIYINEFDKIDHFQDIIHRDIKPQNILIDHEDNDKGEHFKIADFGISVIMEHEQQKKLKNNAGTYCFMAPEF
S_TKc 6544.AA S_TKc 1126-1354 16 3.8e-10 -28.17 SMART 1-231 (231) Show / Hide 
Range on Protein: 1126-1354
Range on HMM: 1-231/231
Sequence Identity: 16% (43 aa)

FLQIQKIENIFTNQSTNVQKINLRVDNSTQDKNIILKTLKSKNFDEAVKEYTFQNCITHRNIHSSYFFQWNEDQNNASITQPLKER---NLYT-IDQ---
.  ..||      .   .....        ..   .| .|    . . .|        | ||   | .  .   ..  .   . .    .|.. |..   
YEILRKIGKGAFGKVYKCRHKK-------TGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGR

------LTYQQFLSIMLDCCEGLQQLTFYNIVHADIKPQNIFYDNQRAQIADFGSCIVSNTQNNEYTPTFCSPESESFESGQRITT-SSDIYSLG-----
      ..  .  ..|   |..|. .   .|.| |.||.||. |. .  |.|||.. .        || ...||          .. ..|..|.|     
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL--TTFCGTPWYMAPEVL------GYGKCKCDWWSCGCILYE

------------KTFQFIAEKFKLPCSGSIQAMILMMTEKEPTRRIRVHEQIK----IIQCEIF
            ..|. |        | .   .|  . .|.|..|. . |  .    | . . |
MLCGYPPFPQMQMMFKKIG-------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 6544.AA ULK 1222-1283 28 7.5e-10 31.2 In-house 126-202 (324) Show / Hide 
Range on Protein: 1222-1283
Range on HMM: 126-202/324
Sequence Identity: 28% (22 aa)

QQFLSIMLDCCEGLQQLTFYNIVHADIKPQNIFYDNQRAQ-------------IADFGSCIV--SNTQNNEYTPTFC
|. .... . |.|.. |   ||.| |||||||   |  ..             ||||| . .  .|...   . |..
QEAIQFFKQICNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCV
Kinase 6544.AA Ciliate-E3 1219-1313 29 8.7e-10 27.0 In-house 100-202 (202) Show / Hide 
Range on Protein: 1219-1313
Range on HMM: 100-202/202
Sequence Identity: 29% (31 aa)

LTYQQFLSIMLDCCEGLQQLTFYNIVHADIKPQNIFYDNQR----AQIADFG-----SCIV--SNTQNNEYTPTFCSPESESFESGQRITTSSDIYSLGK
.| .  . |.    .|.  .   || | ||||.||  |. .    ..|.|||     .     . || .  || . .||       | |   ||.||.| 
KTQNIIYDICIQIIQGMIAIHEKNIIHSDIKPDNILVDKNNNQLIIKICDFGESKQLRKNKGHTHTQYQGWTPFYAAPE---QNDQQQISKESDYYSVGA

TFQFIA
 |  . 
VFCQLC
Kinase 6544.AA ULK 1222-1268 31 8.9e-10 30.39 In-house 130-189 (329) Show / Hide 
Range on Protein: 1222-1268
Range on HMM: 130-189/329
Sequence Identity: 31% (19 aa)

QQFLSIMLDCCEGLQQLTFYNIVHADIKPQNIFYDNQRAQ-------------IADFGSC
|. .... . ..|.. |   ||.| |||||||  .|  ..             ||||| .
QEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFA
Kinase 6544.AA Pkinase 1242-1306 30 9.4e-09 32.03 Pfam 128-199 (293) Show / Hide 
Range on Protein: 1242-1306
Range on HMM: 128-199/293
Sequence Identity: 30% (23 aa)

NIVHADIKPQNIFYD-NQRA----QIADFGSC----IVSNTQNNEY--TPTFCSPESESFESGQRITTSSDIYSLG
.|.| |.||.||..| |        |.|||..    . .|. .. .  || ...||     .|| .....|..|.|
GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV--IRGGQYYGPKVDMWSCG