Gene 6855 (Tetrahymena)

6855

Species: Tetrahymena
Alias: 6855, 1095, 62.m00139, 3715.m00001, PreTt06855, TTHERM_00495900
External Links: Tetrahymena Genome Database (TGD)
Annotation:

Classification

Group: Other
Family: Ciliate-F1

Sequence

Name Sequence Type Origin Length Description Download
6855.AA Protein None 3322 None Fasta, JSON
6855.kin_dom Protein Kinase Domain None 173 None Fasta, JSON
6855.NA RNA None 9969 None Fasta, JSON

Protein domain

Protein domains of 6855.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 6855.AA Ciliate-F1 1701-1874 62 8.60000000001e-133 447.46 In-house 1-174 (174) Show / Hide 
Range on Protein: 1701-1874
Range on HMM: 1-174/174
Sequence Identity: 62% (108 aa)

IHNSGCVHRDIKTDNILKMGNNFLFTDFGESEYVYNLKNFHQKQTDTFRVKQRFSGTQTYLSPLLRECYDNLKNNQSDQLYHDPFKSDIYSLGLVFLQIQ
||||||||||..||||.||||||||||.||||||||..|||..|..|||..||||..|||..|||||||||||.|||.|.||.||.||||.....|.|.|
IHNSGCVHRDYQTDNIIKMGNNFLFTDYGESEYVYNIDNFHHNQNQTFRIQQRFSSNQTYFKPLLRECYDNLKCNQSQQYYHQPFDSDIYHFFKCFQQQQ

LYMKGMNKAEITAILKDPKKAYEEARANNINHIILKQRYFIYEGYEYECINILQSMLEIEENKRMSTIKLALIC
.||||||||.......|||.||.|...|||||...|||||....|.|||.||..||....|.|.|.......| 
SYMKGMNKADFFIMERDPKNAYQETQQNNINHNMNKQRYFHHYWYKYECRNIFMSMMRNVEFKHMYNYYHRDIK
Kinase 6855.AA Ciliate-C6 1659-1797 28 2.8e-14 47.01 In-house 94-244 (306) Show / Hide 
Range on Protein: 1659-1797
Range on HMM: 94-244/306
Sequence Identity: 28% (46 aa)

ELAESSLSKQINNRLEK---------------GVMIDPFSQEEFIFICRWCIQTLVRIHN-SGCVHRDIKTDNILKMGN--NFLFTDFGESEYVYNLKNF
.||||.|  .|... .                 .  . |...| . .|    .||. |.|  . .|||||  ||| | .  |.  .||| ..  .     
DLAESTLQDCIQMKQANVNNFYFKQEINIFSFNYKYEHFDENEIVQFCKQIGKTLADIYNECNIAHRDIKPSNILIMDDENNYYLSDFGCAQQLF-----

HQKQTDTFRVKQRFSGTQTYLSPLLRECYDNLKNNQ----SDQLYHDPFKSDIYSLGLVFL
   | . .|      ||    || |||        |     .|.  | ||.|| |||.. |
---QSEFTRNNDIHMGTLKWMSPELREMKKQYNQHQDDNSNQQI--DYFKCDIFSLGMILL
Kinase 6855.AA C8 1572-1796 24 9.8e-14 44.15 In-house 1-226 (226) Show / Hide 
Range on Protein: 1572-1796
Range on HMM: 1-226/226
Sequence Identity: 24% (59 aa)

FTDIEMIGRGSYGLVLKVKNWQGFERAIKVQLINAYNQDQFKDGEFKIGKYLTDDGTENLFGQIITLHNIYIIQDTESEHMICL--------------ME
| . ...  |.||.||| || .  .| |   .    |... .... .| | .  .    ..  ..  ...   .  . |   |               ||
FNNFQYLSFGAYGMVLKAKNVK-DNREIVLKFQKCQNKQD-IQNIESIMKEYEMPQVFQQYDFYVNEYDCFYEMYEVFEEEKCSNEKIVQTEEKSCFVME

MELAESSLSKQINNRLEKGVMIDPFSQEEFIFICRWCIQTLVRIHNSGCVHRDIKTDNIL-KMGNNFL----FTDFGESEYVYNLKN-FHQKQTDTFRVK
|||.|. | .    | .| .   .||.|.   |    |  .  ||    .||||| .|.| .. .| .      |||.. .|   |. ...|.  |    
MELCEQNLKQLYDERRNKQQ---QFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNT----

QRFSGTQTYLSPLLRECYDNLKNNQSDQLYHDPFKSDIYSLGLVF
    ||..|. |          . | .|.     .||..|.||| 
---CGTWAYFAP-------EIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase 6855.AA Ciliate-B2 1695-1793 33 1e-12 26.12 In-house 114-197 (197) Show / Hide 
Range on Protein: 1695-1793
Range on HMM: 114-197/197
Sequence Identity: 33% (33 aa)

IQTLVRIHNSGCVHRDIKTDNILKMGN-NFLFTDFGESEYVYNLKNFHQKQTDTFRVKQRFSGTQTYLSPLLRECYDNLKNNQSDQLYHDPFKSDIYSLG
|  |....    .| ||| .|||.| | |....|||    .  .|.  |..     .|.    |. | ||   |  .. .| |.  .  | |.|||||.|
IDGLIQFRMYNILHLDIKPQNILFMQNGNYVYCDFG----ISSIKKDNQQI----KIKG---FTKKYASP---EQMECDHN-QTFVTNID-FQSDIYSMG
Kinase 6855.AA S_TKc 1572-1873 15 2.4e-11 -10.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 1572-1873
Range on HMM: 1-231/231
Sequence Identity: 15% (51 aa)

FTDIEMIGRGSYGLVLKVKNWQ-GFERAIKVQLINAYNQDQFKDGEFKIGKYLTDDGTENLFGQIITLHNIYIIQDTESEHMICLMEMELAES---SLSK
.. .. ||.|..| | |...   | . |||.         .    | .| |    .   .|.. . . ...|..             ||...    .| .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMV-------------MEYCDGDLGDLFD

QINNRLEKGVMIDPFSQEEFIFICRWCIQTLVRIHNSGCVHRDIKTDNILKMGNNFLFTDFGESEYVYNLKNFHQKQTDTFRVKQRFSGTQTYLSP-LLR
 | .|  .|    ||.  .  |...  .. |  .|. | .|||.| .|||    .   .||| .  .                   | ||  |..| .| 
YIKKRGRHGLR-FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-----------------TTFCGTPWYMAPEVL-

ECYDNLKNNQSDQLYHDPFKSDIYSLGLVFLQIQL----YMKGMNKAEITAILKDPKKAYEEARANNINHIILKQRYFIYEGYEYECINILQSMLEIEEN
               ....|.|..|.| ..         .    . ...  ...                               |...... .|. . .
--------------GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG-----------------------------SPEAKDFIRKCLQKDPE

KRMSTIKLAL----------I
||..  ..            .
KRPTA-EALQDEWDIKCHPWF
Kinase 6855.AA Ciliate-E1 1578-1781 23 4.6e-11 32.7 In-house 1-202 (202) Show / Hide 
Range on Protein: 1578-1781
Range on HMM: 1-202/202
Sequence Identity: 23% (51 aa)

IGRGSYGLVLK-VKNWQG-FERAIKVQLIN-AYNQDQFKDGEFKIGKYLTDDGTENLFGQIITLHNI-YIIQDTESEHM-ICLMEMELAESSLSKQINNR
||.||...|.| .....   . |.|..... .|||..| |   ..          ...  ...  .| .||.  ...   ||.  .|. . || ....| 
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEY---------YKIMK-FKKECYIIQIIDYIKIDQNYICIIIFECCCCSLKDYLQNH

------LEKGVMIDPFSQEEFIFICRWCIQTLVRIHNSGCVHRDIKTDNILK--MGNNFLFTDFGESEYVYNLKNFHQKQTDTFRVKQRFSGTQTYLSPL
       ..      |...... |    |. |  .|. .  ||||| .|||.    .|....||| |    .|||  ..|.. .  .. .. .. | .|.
NRLEYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQ-GNYVYCDFGISK---FLKNNQNQQCQYKGYTHYYYPPEQYNCPE

LRECYDNLKNNQSDQLY
. | ..| | |.   .|
Q-EHNKNQKINYKSDIY
Kinase 6855.AA Ciliate-C8 1581-1796 21 5.3e-09 28.74 In-house 1-238 (238) Show / Hide 
Range on Protein: 1581-1796
Range on HMM: 1-238/238
Sequence Identity: 21% (54 aa)

GSYGLVLKVKNWQGFERAIKVQLINAYNQDQFKDGEFKIGKY--LTDDGTENLFGQIITLHNIYIIQ-DTESEH----------------MICLMEMELA
|..|.||| .| .  .| .. . .   |. | .  |  | .|  .  .  . .   .. . . ....  ...|                 .   ||||. 
GAFGMVLKAQNKK-QNRKVALKFRECVNKIQKNQMEHEIKEYEMIMQFCQMPF---VVQVYDCFYLMEENKKEDDDGNDKIVQTQEKIKKSFFVMEMEKC

E--SSLSKQINN-RLEKGVMIDPFSQEEFIFICRWCIQTLVRIHNSGCVHRDIKTDNIL---KMGNNF---LFT-----DFGESEYVYNLKN-FHQKQ--
.   .| . ... | ...    ..||.. . |    |  .  .|    .||||| .|.|    .....   |       ||| . .. . |. .| |.  
QQNCNLKQYFDRCRKKQS----YPSQQMKEIIAIQMIDSVNYLHCFNIMHRDIKPHNFLVCFDQQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFK

TDTFRVKQRFSGTQTYLSPLLRECYDNLKNNQSDQLYHDPFKSDIYSLGLVF
.    ... | |. .|  |   | ... . .|||.     .|||.||.|||.
GTDQYIEMYFCGNWGYFAP---EVEKKQSRIQSDIFS---KKSDSYSVGLVL
Kinase 6855.AA Ciliate-E2 1701-1866 16 1.1e-08 25.92 In-house 176-354 (365) Show / Hide 
Range on Protein: 1701-1866
Range on HMM: 176-354/365
Sequence Identity: 16% (35 aa)

IHNSG-CVHRDIKTDNILKMGNNFLFTDFGESEYVY-------------NLKNFHQKQTDTFR---------VKQRFSGTQTYLSP--LLRECYDNLKNN
.|. . ..||||| .|||        .||| | ..              .... ... . |..         . ... ||  |..|  | .. |||    
LHSKNNIIHRDIKPENILF----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQ---

QSDQLYHDPFKSDIYSLGLVFLQIQLYMKGMNKAEITAILKDPKKAYEEARANNINHIILKQRYF------------------IYEGYEYECINILQS--
   .  .  .|.||.||| .. .                                  .|... .                   ...  . ||.....   
--QKQKGYDYKCDIWSLGVILYEMLFGKPPF------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFG

--MLEIEENKRMS
  ||. ...||..
KRMLQKDPEKRIT
Kinase 6855.AA Ciliate-E2-Unclassified 1682-1796 24 4.4e-08 24.16 In-house 135-260 (352) Show / Hide 
Range on Protein: 1682-1796
Range on HMM: 135-260/352
Sequence Identity: 24% (33 aa)

FSQEEFI-----FICRWCIQTLVRIHNSG-CVHRDIKTDNIL--KMGN--NFLFTDFGESEYVYNLKNF-----HQKQTDTFRVKQRFSGTQTYL----S
|. .. .     |...  .| |  .| .. ..||||| .|||  . |.  .   .||| | .  .  |.      ..|   .   . |.||  |.    .
FTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTA

PLLRECYDNLKNNQSDQLYHDPFKSDIYSLGLVF
|   |.... ....|       .|.||.||| ..
P---EVLQGQNYDHSKA-----YKCDIWSLGVIL
Kinase 6855.AA Ciliate-A5 1702-1798 20 2.6e-07 21.51 In-house 116-210 (275) Show / Hide 
Range on Protein: 1702-1798
Range on HMM: 116-210/275
Sequence Identity: 20% (20 aa)

HNSGCVHRDIKTDNILKMGNNFL-FTDFGESEYVYNLKNFHQKQTDTFRVKQRFSGTQTYLSPLLRECYDNLKNNQSDQLYHDPFKSDIYSLGLVFLQ
. .. .|.||.  ||. . ....  .|..||     . |. .... .  .   . .. .||||.. .   .    .. .  |. .|||...||.. |.
QQNNICHGDIRPQNICLTQDGQVKLMDMNESKDFFYQINWSSYKQYQHHM---STENKQYLSPMQWYQMMHRDEQNIQRPEHNWYKSDVFCLGMICLE
Kinase 6855.AA STE 1658-1717 28 2e-06 18.61 In-house 116-184 (359) Show / Hide 
Range on Protein: 1658-1717
Range on HMM: 116-184/359
Sequence Identity: 28% (20 aa)

MELAE-SSLSKQINNRLEKGVMID-------PFSQEEFIFICRWCIQT-LVRIHNSGCVHRDIKTDNIL
||. .  ||.. |... ..| . .       .|. .. ..||| ...  |  .|. . .||||| .|||
MEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANIL
Kinase 6855.AA STE 1572-1601 28 0.000294 11.08 In-house 1-46 (359) Show / Hide 
Range on Protein: 1572-1601
Range on HMM: 1-46/359
Sequence Identity: 28% (13 aa)

FTDIEMIGRGSYGLVLKVKNW----------------QGFERAIKV
...||.||.|..| | | .|                 .|.  |||.
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQ
Kinase 6855.AA TyrKc 1572-1803 13 0.00037 -155.39 SMART 1-280 (280) Show / Hide 
Range on Protein: 1572-1803
Range on HMM: 1-280/280
Sequence Identity: 13% (41 aa)

FTDIEMIGRGSYGLVLKVKNWQGFERAIKVQLINAYNQDQFKDGEFKIGKYLTDDGTENLFGQIITLHNI------------YIIQD----TESEHMICL
 | ....|.| .| | | .     . |.|.   .|                      | .   .  ....            ...|.     ..| .  .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIV

MEMELAESSLSKQINNRLEKGVMIDPFSQEEFIFICRWCIQTLVRIHNSGCVHRDIKTDNILKMGNNFLF--TDFGESEYVYNL-------KNFHQK---
||   .  .| . . .. .|      .. .... .|    .    .|  .|.|||. . |.|  |.|.    .||| | ..|.        .  ..|   
MEY-MPHGDLKDYLRKHRPK------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCL-VGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHK

QTD-----------TFRVKQRFS------------------GTQTYLS-----PLLRECYDNLKNNQSDQLYHDP-------FKSDIYSL----------
...           ..  . .|.                  | | |          .| . ..|.       ...         ...|..          
GGKTMLPIRWMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPE

-GLVFLQIQLYM
    | .|  ..
DRPTFSEIHECF
Kinase 6855.AA Ciliate-A5 1850-1874 36 0.000398 10.31 In-house 251-275 (275) Show / Hide 
Range on Protein: 1850-1874
Range on HMM: 251-275/275
Sequence Identity: 36% (9 aa)

INILQSMLEIEENKRMSTIKLALIC
||..  ||..||||| . .... . 
INFIKQMLQFEENKRPDFHQIYQYL
Kinase 6855.AA Ciliate-E2-Unclassified 1572-1618 25 0.001986 7.78 In-house 274-323 (352) Show / Hide 
Range on Protein: 1572-1618
Range on HMM: 274-323/352
Sequence Identity: 25% (13 aa)

FTDIEMIGRGSYGLVLKVKNWQGFERA-----IKVQLINAYNQDQFKDGEFK
.. |. ||.|..| | |... .    .     .|.. |.. .| ..|| |..
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIM
Kinase 6855.AA Pkinase 1701-1717 52 0.00405 12.11 Pfam 124-140 (293) Show / Hide 
Range on Protein: 1701-1717
Range on HMM: 124-140/293
Sequence Identity: 52% (9 aa)

IHNSGCVHRDIKTDNIL
.|. |..|||.| .|||
CHSMGIIHRDLKPENIL
Kinase 6855.AA Ciliate-E2 1572-1593 40 0.005389 6.1 In-house 1-22 (365) Show / Hide 
Range on Protein: 1572-1593
Range on HMM: 1-22/365
Sequence Identity: 40% (9 aa)

FTDIEMIGRGSYGLVLKVKNWQ
.  |..||.|..| | |.|.|.
YKFIKKIGQGNFGSVYKCKVWK
Kinase 6855.AA Pkinase 1572-1591 35 0.086997 7.4 Pfam 1-20 (293) Show / Hide 
Range on Protein: 1572-1591
Range on HMM: 1-20/293
Sequence Identity: 35% (7 aa)

FTDIEMIGRGSYGLVLKVKN
.. .. ||.||.| | | ..
YHIGRKIGSGSFGCVYKCHH
Kinase 6855.AA Ciliate-C6 1576-1591 50 0.118709 1.63 In-house 5-20 (306) Show / Hide 
Range on Protein: 1576-1591
Range on HMM: 5-20/306
Sequence Identity: 50% (8 aa)

EMIGRGSYGLVLKVKN
  .|.||.| | |.||
DSLGSGSFGQVYKCKN
MORN 6855.AA MORN 1948-1964 41 0.000285 20.27 Pfam 1-17 (23) Show / Hide 
Range on Protein: 1948-1964
Range on HMM: 1-17/23
Sequence Identity: 41% (7 aa)

YEGYWSKDLPHGQGKFS
||| |.....||.|...
YEGEWKNGKMHGHGVYT