Gene MSN (Sea Urchin)
MSN
Sequence
Protein domains of MSN.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | MSN.AA | MSN | 128-249 | 85 | 2.1e-96 | 318.89 | In-house | 144-265 (265) | Show / Hide |
Range on Protein: 128-249 Range on HMM: 144-265/265 Sequence Identity: 85% (104 aa) KIVDFGVSAQLDKTIGRRNTFIGTPYWMAPEVIACDENPDATYDNKSDLWSLGITALEMAEGQPPLCDMHPMRALFLIPRNPKPKLKSKKWNKKFMDFVD |.||||||||||.|.|||||||||||||||||||||||||||||..|||||.||||.|||||||||||||||||||||||||.||||||||.|||..|.. KLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGITAIEMAEGQPPLCDMHPMRALFLIPRNPPPKLKSKKWSKKFHNFME KCLIKNYQQRPDTNQLLKHSFI |||||||.|||.|.|.|||.|| KCLIKNYHQRPYTEQMLKHPFI |
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| Kinase | MSN.AA | STE20 | 128-249 | 62 | 2.4e-81 | 276.57 | In-house | 157-288 (288) | Show / Hide |
Range on Protein: 128-249 Range on HMM: 157-288/288 Sequence Identity: 62% (82 aa) KIVDFGVSAQLDK----TIG-RRNTFIGTPYWMAPEVIACDENPDATYDNKSDLWSLGITALEMAEGQPPLCDMHPMRALFLIP--RNPKPKLK---SKK |..||||.|||.| |.. .||||.|||||||||||.|.|.|| ||.|.| |||||||.|||||.||..|||||||.|.|| .||.|.|| ..| KLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHK WNKKFMDFVDKCLIKNYQQRPDTNQLLKHSFI | ..| ||||||| |....|| . |||||.|| WSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI |
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| Kinase | MSN.AA | YSK | 128-249 | 55 | 4.1e-70 | 210.2 | In-house | 139-257 (257) | Show / Hide |
Range on Protein: 128-249 Range on HMM: 139-257/257 Sequence Identity: 55% (69 aa) KIVDFGVSAQLDKTIGRRNTFIGTPYWMAPEVIAC--DENPDATYDNKSDLWSLGITALEMAEGQPPLCDMHPMRALFLIPRNPKPKLKSKKWNKKFMDF |. ||||..|. | .||||.||||||||||| . .. || | | |||||||.||| |.||.||.||||..|||| |. |||. ... | | .| KLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSY-----YDFKADIWSLGITAYEMAKGEPPYCDYHPMRVMFLIPKNNPPKLEGRSYSKMFKEF VDKCLIKNYQQRPDTNQLLKHSFI |. || |. .||| .||||.|| VECCLNKDPEQRPSAKELLKHKFI |
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| Kinase | MSN.AA | STE | 128-249 | 40 | 1.3e-67 | 230.96 | In-house | 187-359 (359) | Show / Hide |
Range on Protein: 128-249
Range on HMM: 187-359/359
Sequence Identity: 40% (70 aa)
KIVDFGVSAQLDK---------------TIG-RRNTFIGTPYWMAPEVIACDENP-DATYDNKSDLWSLGITALEMAEGQPPLCDMHPMRALFLIPRN--
|..||||..||.. |.. .||||.||| ||||||| ..... | || |.| ||||.|..|||.|.||..|||||||.|.||.|
KLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYH
-------------PKPKLKS------------------KKWNKKFMDFVDKCLIKNYQQRPDTNQLLK--HSFI
| |.|.. .|| ..| ||..|||.|....||...|||| |.||
MQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
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| Kinase | MSN.AA | NinaC | 128-249 | 57 | 3.2e-65 | 222.99 | In-house | 145-267 (267) | Show / Hide |
Range on Protein: 128-249 Range on HMM: 145-267/267 Sequence Identity: 57% (71 aa) KIVDFGVSAQLDKTIGRRNTFIGTPYWMAPEVIACDENPDATYDNKSDLWSLGITALEMAEGQPPLCDMHPMRALFLIPRNPKPKLKS-KKWNKKFMDFV | .||||||||| | .|||| .|||.||||||||| . | .|| | ||||||| |.. | ||. |||||||.| ||||| |.| .| ..| ||. KLCDFGVSAQLDSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLGITAIELGDGDPPFADMHPMRAMFKIPRNPPPTLMHPENWCQEFNDFI DKCLIKNYQQRPDTNQLLKHSFI .||.|.| .|| ..|.| || SQCLEKDYEKRPMMVHMLEHPFI |
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| Kinase | MSN.AA | MST | 131-249 | 59 | 1.3e-64 | 204.23 | In-house | 140-254 (254) | Show / Hide |
Range on Protein: 131-249 Range on HMM: 140-254/254 Sequence Identity: 59% (71 aa) DFGVSAQLDKTIGRRNTFIGTPYWMAPEVIACDENPDATYDNKSDLWSLGITALEMAEGQPPLCDMHPMRALFLIPRNPKPKLKS-KKWNKKFMDFVDKC |||||.|| | . |||.|||||||||||| ||.| | |||||||.||||| ||. | |||||.|.|| .| |..| .| |.||| || DFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQ-----EIKYDCKADIWSLGITAIEMAEGMPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKC LIKNYQQRPDTNQLLKHSFI |.|| .||. |||.|.|| LQKNPEQRWTAEQLLQHPFI |
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| Kinase | MSN.AA | PAKL | 128-249 | 49 | 4.8e-52 | 179.22 | In-house | 138-256 (256) | Show / Hide |
Range on Protein: 128-249 Range on HMM: 138-256/256 Sequence Identity: 49% (61 aa) KIVDFGVSAQLDKTIG-RRNTFIGTPYWMAPEVIACDENPDATYDNKSDLWSLGITALEMAEGQPPLCDMHPMRALFLIPRNPKPKLKS-KKWNKKFMDF || ||||| ||. . . | ||||||||||.| . |.|| | ||||||| |||.| ||. || ||||. ||. | |... |.| . | || KIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIINK-----QNYNNKCDIWSLGITAIEMADGFPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDF VDKCLIKNYQQRPDTNQLLKHSFI ...|. | .|. .|| | || LAQCCVKDPEKRWSPIDLLCHPFI |
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| Kinase | MSN.AA | SLK | 128-249 | 49 | 7.1e-51 | 169.81 | In-house | 137-259 (259) | Show / Hide |
Range on Protein: 128-249 Range on HMM: 137-259/259 Sequence Identity: 49% (61 aa) KIVDFGVSAQLDKTIGRRNTFIGTPYWMAPEVIACDENPDATYDNKSDLWSLGITALEMAEGQPPLCDMHPMRALFLIPRNPKPKLKS-KKWNKKFMDFV .. ||||||.. .|. .| |||||||||||||..|. |. || |.|.|||||| .|||.. || .| ||| |. | . |.|. .| |.| ||. RLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQMEPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFL DKCLIKNYQQRPDTNQLLKHSFI ||| |. |.|. |.||..| .. KKCLVKDPQNRWTTAQLMQHQWV |
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| Kinase | MSN.AA | MSN | 13-127 | 59 | 3.7e-49 | 160.34 | In-house | 1-115 (265) | Show / Hide |
Range on Protein: 13-127 Range on HMM: 1-115/265 Sequence Identity: 59% (68 aa) FHVLKKMGNGFRGSVMRSYHRKKGILKRIALTMVTGNFREQLKSFSFLFVQYSHHRNIATYYGAFIKKGVKNHDDQLWLVMEFCGAGSVTDLVKATKGNA |.. . .||| | | . | | | | | . |. . |..| . .||||||||||||||||| ||.|||.||||||||||||||| |||.. FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVREDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVKMTKGQS LKEEWIAYICREILR |||.||||||||||| LKEDWIAYICREILR |
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| Kinase | MSN.AA | KHS | 128-249 | 52 | 6.5e-49 | 162.58 | In-house | 136-258 (258) | Show / Hide |
Range on Protein: 128-249 Range on HMM: 136-258/258 Sequence Identity: 52% (65 aa) KIVDFGVSAQLDKTIGRRNTFIGTPYWMAPEVIACDENPDATYDNKSDLWSLGITALEMAEGQPPLCDMHPMRALFLIPRNP--KPKLKSK-KWNKKFMD |. |||||||. ||..| |||||||||||| | . . |.. |.|..||||.|.|| |||. |.||||||||. . |||| | || ..| . KLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERK--GGYNQLCDIWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHH FVDKCLIKNYQQRPDTNQLLKHSFI || .|.|| ..|| ..||.| |. FVKMALTKNPKKRPTAEKLLQHPFV |
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| Kinase | MSN.AA | PAKA | 128-249 | 49 | 2.5e-47 | 163.57 | In-house | 143-260 (260) | Show / Hide |
Range on Protein: 128-249 Range on HMM: 143-260/260 Sequence Identity: 49% (61 aa) KIVDFGVSAQLDKTIGRRNTFIGTPYWMAPEVIACDENPDATYDNKSDLWSLGITALEMAEGQPPLCDMHPMRALFLIPRNPKPKLKSK-KWNKKFMDFV || ||| ||| . .||| ||||||||||| . || | | ||||| |.||.||.|| .. | ||..|| | ||..|.. || ..| ||. KITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQ-----YDEKVDIWSLGIMAIEMIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFL DKCLIKNYQQRPDTNQLLKHSFI |||| .. ..|... .||.| |. DKCLCVDVDRRASAQELLHHPFL |
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| Kinase | MSN.AA | S_TKc | 13-249 | 23 | 1.4e-36 | 128.72 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 13-249 Range on HMM: 1-231/231 Sequence Identity: 23% (66 aa) FHVLKKMGNGFRGSVMRSYHRKKGILKRIALTMVTGNFREQLKSFSFLFVQYSHHRNIATYYGAFIKKGVKNHDDQLWLVMEFCGA--GSVTDLVKATKG ...|.| | | |.|.. .|.| .. |. .. |.... . . || || ..|..| | |..|||.|. |.. |. | .. YEILRKIGKGAFGKVYKCRHKK--TGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGR NA----LKEEWIAYICREILR--------------------------KIVDFGVSAQLDKTIGRRNTFIGTPYWMAPEVIACDENPDATYDN-KSDLWSL . . | ........|.. || |||...|| .||.|||..|||||. |. |.| ||. HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDEHIKICDFGLARQL-------TTFCGTPWYMAPEVL--------GYGKCKCDWWSC GITALEMAEGQPPLCDMHPMRALFLIPRNPKPKLKSKKWNKKFMDFVDKCLIKNYQQRPDTNQLLK-------HSFI |.. ||. |.|| . .... . .| . . ||..||| |. ..|| ..|. | .. GCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | MSN.AA | Pkinase | 128-249 | 28 | 3.7e-29 | 104.19 | Pfam | 152-293 (293) | Show / Hide |
Range on Protein: 128-249
Range on HMM: 152-293/293
Sequence Identity: 28% (42 aa)
KIVDFGVSAQL-DKTIGRRNTFIGTPYWMAPEVIACDENPDATYDNKSDLWSLGITALEMAEGQPPLCDM----HPMRALFLIPRNPKPKLKSKKW----
|| |||...|. . .|| |||..|||||| . |. |.| ||.|.. ||. |.|| .. . .. ...| |. .|.|.. .
KICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR----GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCS
------------------NKKFMDFVDKCLIKNYQQRPDTNQLLKHSFI
.. . ||...|| |. ..|| |.|.| ..
ISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
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| Kinase | MSN.AA | STE20 | 13-127 | 34 | 3.4e-26 | 92.92 | In-house | 1-128 (288) | Show / Hide |
Range on Protein: 13-127 Range on HMM: 1-128/288 Sequence Identity: 34% (45 aa) FHVLKKMGNGFRGSVMRSYHRKKGIL-------KRIALTMV---TGNFREQLKSFSFLFVQYSHHRNIATYYGAFIKKGVKNHDDQLWLVMEFCGAGSVT . |.| |.| |.| . ||.. | . |.. | . .| .. |. | || .|||...|. . ||.||.|||.||.||.| YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQ-DEWEDIQKEISIMKQCK-HPNIVKYYGSYLKDDTC--DDELWIVMEYCGGGSLT DLVK---ATKGN----ALKEEWIAYICREILR |..| ...| ..||.|||||||.|. DIMKHCMKCGKNHKGHPMNEEQIAYICREVLQ |
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| Kinase | MSN.AA | STE | 13-127 | 23 | 4e-23 | 78.56 | In-house | 1-162 (359) | Show / Hide |
Range on Protein: 13-127 Range on HMM: 1-162/359 Sequence Identity: 23% (38 aa) FHVLKKMGNGFRGSVMRSYHRKKGILK-------------RIALTMVT--------------------GNFREQLKSFSFLFVQYSH-HRNIATYYGAFI . ..| |.| |.| . ...|.... ..| . . ..|.. . ...| | || .|||... WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF KKGV-KNHDDQLWLVMEFCGAGSVTDLVKA--TKGNALK----------EEWIAYICREILR |.| .. ||.||..||....||..|..| .|. |. |..||||||.||. KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILK |
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| Kinase | MSN.AA | KHS | 13-127 | 26 | 1.1e-16 | 52.46 | In-house | 1-107 (258) | Show / Hide |
Range on Protein: 13-127 Range on HMM: 1-107/258 Sequence Identity: 26% (31 aa) FHVLKKMGNGFRGSVMRSYHRKKGILKRIALTMVTGNFREQLKSFSFLFVQYSHHRNIATYYGAFIKKGVKNHDDQLWLVMEFCGAGSVTDLVKATKGNA . .|...| | | | . . . . | . . . . .. . .. .| || |.|..... |.||..||.||.||. |. ..| YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRR------DKLWICMEYCGGGSLQDIYHVT--GP LKEEWIAYICREILR |.| |||.|||.|. LSELQIAYVCRETLQ |
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| Kinase | MSN.AA | PAKA | 65-127 | 36 | 1.6e-15 | 51.1 | In-house | 55-114 (260) | Show / Hide |
Range on Protein: 65-127 Range on HMM: 55-114/260 Sequence Identity: 36% (24 aa) SHHRNIATYYGAFIKKGVKNHDDQLWLVMEFCGAGSVTDLVKATK---GNALKEEWIAYICREILR ..| || |. ... | ||.||.|||. ..|. ||..... | ..|. |||.|||.|. CKHKNIVNYIDSYL---V---DDELWVVMEYMEGGCLTDVITQCCNIQCNYMDEGQIAYVCRECLQ |
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| Kinase | MSN.AA | MST | 69-127 | 37 | 2.6e-15 | 45.04 | In-house | 55-108 (254) | Show / Hide |
Range on Protein: 69-127 Range on HMM: 55-108/254 Sequence Identity: 37% (23 aa) NIATYYGAFI--KKGVKNHDDQLWLVMEFCGAGSVTDLVKATKGNALKEEWIAYICREILR .| .||| .. | . ..|.|||.||.||| |..|.|. | |. || |.. |. YIVKYYGSYFDAK------NNHCWIVMEYCGMGSVCDIMKITQ-RTLNEQQIACILYDTLQ |
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| Kinase | MSN.AA | NinaC | 63-127 | 46 | 8.3e-15 | 53.03 | In-house | 51-116 (267) | Show / Hide |
Range on Protein: 63-127 Range on HMM: 51-116/267 Sequence Identity: 46% (31 aa) QYSHHRNIATYYGAFIKKGVKNHDDQLWLVMEFCGAGSVTDLVKA--TKGNALKEEWIAYICREILR .|. | |. .|| . || |. ||||.|||.| |||||.|| | ..|| |||| .| .. DYCDHPNVVRFYGMYYKKD-KCNGDQLWFVMEYCNGGSVTDMVKGLLKCGRRMREEHIAYILHEACM |
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| Kinase | MSN.AA | YSK | 69-126 | 43 | 5.7e-14 | 38.1 | In-house | 58-109 (257) | Show / Hide |
Range on Protein: 69-126 Range on HMM: 58-109/257 Sequence Identity: 43% (25 aa) NIATYYGAFIKKGVKNHDDQLWLVMEFCGAGSVTDLVKATKGNALKEEWIAYICREIL .| |||.. | | || .||.|| ||. || |. ... |. || | |||| YITKYYGSYLK------DTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKYIAIILREIL |
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| Kinase | MSN.AA | TyrKc | 13-249 | 18 | 3.5e-08 | -90.29 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 13-249
Range on HMM: 1-280/280
Sequence Identity: 18% (57 aa)
FHVLKKMGNGFRGSVMRSYHRKKGI------LKRIALTMVTGNFREQLKSFSFLFVQY-SHHRNIATYYGAFIKKGVKNHD---DQLWLVMEFCGAGSVT
. .|| |.|. | |.. . | || | || . . . .. || || ||. ...| . ..|..|||.. |.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDLK
DLVKATKGNALKEEWIAYICREI----------------------------LRKIVDFGVSAQLDKT--------IGRRNTFIGTP-----YWMAPEVIA
| ...... |. . ..| | || ||| | .. | . |. |||||.|
DYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-
CDENPDATYDNKSDLWSLGITALEMAE-GQPPLCD-----MHPMRALFLIPRNPKPKLKSK-------KWNKKFMDFVDKCLIKNYQQRPDTNQLLKHSF
. .. ||| || |.. |. ||.| . | . ... .. . .. .. . .| . .|| ... |..
----NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HEC
I
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F
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| Kinase | MSN.AA | Pkinase | 13-127 | 20 | 5.6e-08 | 29.3 | Pfam | 1-119 (293) | Show / Hide |
Range on Protein: 13-127 Range on HMM: 1-119/293 Sequence Identity: 20% (26 aa) FHVLKKMGNGFRGSVMRSYHRKKG---ILKRIALTMVTGNFREQLKS-FSFLFVQYSHHRNIATYYGAFIKKGVKNHDDQLWLVMEFCGAG----SVTDL .|...| | | |.| . .|.. | .|.| . ...... . .| || ..|..| .| ...|||.|. | . |. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDLFDY VKATKGNAL--KEEWIAYICREILR ... ..... |. . ....||| ISTWRHGCFYFSEWECKFYMYQILR |
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| Kinase | MSN.AA | SLK | 13-126 | 24 | 3.5e-07 | 20.14 | In-house | 1-107 (259) | Show / Hide |
Range on Protein: 13-126 Range on HMM: 1-107/259 Sequence Identity: 24% (28 aa) FHVLKKMGNGFRGSVMRSYHRKKGILKRIALTMVTGNFREQLKSF--SFLFVQYSHHRNIATYYGAFIKKGVKNHDDQLWLVMEFCGAGSVTDLVKATKG .... .|.| | | . |. .... | |. . |.|. . . .| || |.|. .|..||...|||. | | | . . WEIIGELGDGAFGKVYKAQHKEQKVF--AAAKMIEIKDEEELEDYMVEIDILSECKHPNIVKLYEAYY------YDNKLWMMIEFCDGGAV-DNIMVELE NALKEEWIAYICREIL .|.|. |.|.|.... HPLTEDQIQYVCKHMC |
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| Kinase | MSN.AA | PAKL | 87-127 | 26 | 0.000832 | 10.45 | In-house | 70-109 (256) | Show / Hide |
Range on Protein: 87-127 Range on HMM: 70-109/256 Sequence Identity: 26% (11 aa) DQLWLVMEFCGAGSVTDLVKATKGNALKEEWIAYICREILR ...| |..| .||. |. . . . |.|. |. | . |. NHYWILMDYCSLGSINDMMESC-CKTLNEKQISVILQQTLK |
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| Kinase | MSN.AA | Pkinase_Tyr | 66-125 | 27 | 0.001272 | 12.89 | Pfam | 62-120 (270) | Show / Hide |
Range on Protein: 66-125 Range on HMM: 62-120/270 Sequence Identity: 27% (17 aa) HHRNIATYYGAFIKKGVKNHDDQLWLVMEFCGAGSVTDLVKAT--KGNALKEEWIAYICREI || || .||. ...| | |...|||.. |. | .. ...|. ... .|..| HHPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQI |
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| Kinase | MSN.AA | Pkinase_Tyr | 154-205 | 31 | 0.009847 | 9.88 | Pfam | 180-228 (270) | Show / Hide |
Range on Protein: 154-205 Range on HMM: 180-228/270 Sequence Identity: 31% (17 aa) WMAPEVIACDENPDATYDNKSDLWSLGITALEMAE-GQPP-LCDMHPMRALFLI |||||.|. . . ||| || |.. |. |. | .| . . . .| WMAPECINYGK-----FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI |
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| CNH | MSN.AA | CNH | 572-870 | 25 | 1.2e-99 | 338.32 | SMART | 1-375 (375) | Show / Hide |
Range on Protein: 572-870 Range on HMM: 1-375/375 Sequence Identity: 25% (94 aa) YRKKFNSEILCASLWGVNLLIGTDSGLMLLDRSGE------GKVYPLISRKRFQQMDVLESQNILVCIAGKKNKLRTYFLSWLKQK------------IV ...|....|.|. |||..||.||..|...|.... |.......|.....|.|.| .|.|. |.||| .|. . |.||.|| . CTMKWCHPITCDQLWGKWLLVGTEHGIYCLNINCQQNQDHEGTPEHIHHRRCVTCMWVYEENNCLMMISGKKPHLYSHPLVWLFQKYRTQGMTPHIQDHM RSDGEAKRKSGF-LSVGDLEG-CIHYKI-IKYEK--IKFLVIALKDSIEIYAWAPKPYHKFMAFKS----------------FPNLVHRPLIVDLTVEDN ... || . ..|..| |.|... ... |.||. |.. |..||.....|.|||| .|| || ... |..|....... CNHHLVPRKNVWTTKIPDTKGNCHHCCVKCNGKRTGIIFLCHAMQHSVQIYNQWYNPMHKFMCWKSSNNILNNEIEMFKHFRFPEIFPVPVFVCFHHDSF QRLKVIYGSVN------GFHAIDLD-------------SASVQDIYSPPQEIGTI------TPYCVVILPNSQG---KYLLLCFNNEGVFVDTKG---VP .|.....|. |||... . . .. |........ |. .| .|.....|.| .|||..|.||||.. | ERPWICIGCDKPVGGMYGFHMVQHHQHCHCNSFNMHESTVNMNDHSLWFMNQQTSHQQDTCKPHQVHQVQQSDGGQRDMYLLCYDNFGVFVNCYGSEWRR FKDVILQWGELPASVAYISTGQIMGWGNKAIEIRSAETGHL-DGVFMHK---RSQQLRFLCE---RNDKVFFASIR ...||.|.. | ..||.. ..||......|.||. .||.. ....|.. ... .|.||. |..|.|..|.. WRNPILHWEFMPEYFAYHY-PYIMAFWDNGIQIRHIKTGEWNTQCIMDRQYIKCRKFRLLCTCECRDRKIFYCSQP |
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| CNH | MSN.AA | CNH | 581-861 | 22 | 9.6e-78 | 269.38 | Pfam | 1-336 (336) | Show / Hide |
Range on Protein: 581-861
Range on HMM: 1-336/336
Sequence Identity: 22% (75 aa)
LCASLWGVNLLIG-TDSGLMLLDR------SGEGKVYPLISRKRFQQMDVLESQNILVCI--AGKKNKLRTYFLSWLKQKIVRSDGEAKRKS--------
.|. ||..||.| ||.||..... ....... ..|| |..|..|.| .|||..| ..| ..|. . |.||.||.. .. .. |.
VCPCTWGQWLLVGTTDEGLYVYNIRNTRDCRHWTRICQKFSR-RVTQIYVIEEFNILIMISGCDKNKHLYVHPLDWLDQKEQQWHQCHNPKHRCTHRIER
-------GFLSVGDLEGCIHYK--IIKYEKIKFLVIALKD-----SIEIYAWAP--KPYHKF-------MAFKSFPN-LVHR----PLIVDLTVEDNQRL
. ..|. .|.... .|.....|..|.| .| .| |.. |..||. ..|. |. . . ........ .....
IMPRKFAMWQKLPDTKHCHFFCWIRNGYCNGRCLCCAVKRSGLHSTIKCYEWYHPMKKFHKQRSFKGNQEWFRKFRECFYIPLPPMTECFSMHWLPQEKP
KVIYGSVNGFHAIDLD-SASVQDIYSPPQE---------IGTITPYCVVILPNSQGKYLLLCFNNEGVFVDTKGV-PFK--DVILQWGELPASVAYISTG
|...|. .|||...|| ... .....| . ...| |.. .... . .|||.....|.|.. | . . |....| . | |.|. ...
KLCVGCQKGFHIVNLDGTGQPWWLHDPADHSVQQDFMARRENCKPICMHRINDD-E-EFLLCYDECCVYVNKQGWPRSRKHDWEIMWEGMPQSFAC-CYP
QIMGWGNKAIEIRSAETG-HLDGVFMHKRSQQLRFLCERN
..... ..||||..||| ..|..... . | .|||....
YLLAFHPNFIEIRHVETGSEWDACVQCIPGQNIRFLHSGS
|
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