Gene n169 (Tetrahymena)
n169
Species: Tetrahymena
Alias: n169, 169, 3825.m02530
External Links:
Annotation:
Group:
Other
Family:
Ciliate-E4
Sequence
Protein domains of n169.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | n169.AA | Ciliate-A5 | 31-293 | 29 | 7.1e-50 | 171.02 | In-house | 1-275 (275) | Show / Hide |
Range on Protein: 31-293 Range on HMM: 1-275/275 Sequence Identity: 29% (83 aa) SFGDIQILKDKSSDNQVGLKEFNLTDESEFAKTIEKFKPKLALDNPNLIKLHNCIQNKESQFCSTFFKVYLVFEYVKNTLEQEVQERSKDQ-KQPFSEEE | . | | . | . ||. . ...| |. ||..|| . ..|...|||.|.|| ...||. |.||||.|.|.. | ...| | FYGCMKIWKNQHQQEYYICKQKQIQDEDRQKHFQQYFEQRMQLQHPNIVKLIDFHTHKKEEFCSQFYKVNCYYEYHDNNLEQEMQMRKQCQKDIFYNEQE MWNILTSCIQGAHFLYQNKLSNNNIRPSTIYITSNGIVKLADPT---------LFSQQGLYPAALSSPNNVPQGIYISPELLNDMYQQ----QYNPVYNQ | |. . |. .| ||.. .|||..| .| .| |||.| .|. . | ..| | . |.||.... |. .|..| LWYIMDCLISVCMYLQQNNICHGDIRPQNICLTQDGQVKLMDMNESKDFFYQINWSSYKQYQHHMSTEN----KQYLSPMQWYQMMHRDEQNIQRPEHNW QKADVFSIGMCMLHAALLQPL-DDLYDYKTFQINEALLHERLNQVRE-NYGDLLYQYLYHMLNFNADDRQDIAYFYQQI .| |||..|| .| .... . |||.|||| . | . | |. | |.. .. . ||.|. .| |. ||. YKSDVFCLGMICLEMCTMRDCTQFYYDYETFQIQNNQLIKQLIQMKEKKYSEQFINFIKQMLQFEENKRPDFHQIYQYL |
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| Kinase | n169.AA | Ciliate-E4 | 21-171 | 28 | 3.7e-36 | 117.73 | In-house | 1-150 (150) | Show / Hide |
Range on Protein: 21-171 Range on HMM: 1-150/150 Sequence Identity: 28% (43 aa) FQQQEKLNHPSFGDIQILKDKSSDNQVGLKEFNLTDESEFAKTIEKFKPKLALDNPNLIKLHNCIQNKESQFCSTFFKVYLVFEYVKNTLEQEVQERSKD . . | .|||||. | . .| | . . | | .|.|.. .. ||.||||.. ..|...||.. |.|... . | YRKIESVKDIHYGDIQIMEHKIQKQIIVMKIRKFQNETKARQQQQQFRRRQDLNHENIIMVYEYFHKKEDQFCSSIYRLYWFMEYLQKDLQQHIKQH-KQ QKQPFSEEEMWNILTSCIQGAHFLYQNKLSNNNIRPSTIYITSNGIVKLAD | |.|.| |.|.|. .|| . .|.| . ....|| | .. . ||.|| QGQHFDESEIWQIAFCCINAMYYLQQVNITHGDLKPSNIFFDQYFMVKIAD |
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| Kinase | n169.AA | S_TKc | 21-300 | 15 | 3.9e-08 | -57.56 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 21-300 Range on HMM: 1-231/231 Sequence Identity: 15% (44 aa) FQQQEKLNHPSFGDIQILKDKSSDNQVGLKEFNLTDESEFAKTIEKFKPKLALDNPNLIKLHNCIQNKESQFCSTFFKVYLVFEYVKN---TLEQEVQER .. .|. . .|| ..|... .| .|. . | | . ||..||. ..|. ..|.|.||. . .| . ..| YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD---------DHLYMVMEYCDGDLGDLFDYIKKR SK-DQKQPFSEEEMWNILTSCIQGAHFLYQNKLSNNNIRPSTIYITSNGIVKLAD---PTLFSQQGLYPAALSSPNNVPQG--IYISPELLNDMYQQQYN . ..||.| . . .. ... .. ... . |. | ... .|..| ... . | |..||.| GRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------------TTFCGTPWYMAPEVL--------- PVYNQQKADVFSIGMCMLHAALL--QPLDDLYDYKTFQINEALLHERLNQVRENYGDLLYQYLYHMLNFNADDRQDIAYFYQ--QINLQQEYA |. |.|. |.| |.| | | . ....|.. . . . . ..|... ..| . | . . .. -GYGKCKCDWWSCG-CILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | n169.AA | WEE | 110-232 | 20 | 4.6e-07 | 19.82 | In-house | 93-230 (297) | Show / Hide |
Range on Protein: 110-232 Range on HMM: 93-230/297 Sequence Identity: 20% (31 aa) LEQEVQERSKDQKQPFSEEEMWNILTSCIQGAHFLYQN-KLSNNNIRPSTIYITSNG--------------------IVKLADPTLFSQQGLYPAALSSP | | .. .. .. ..|.. |.|| .|| |.. .| . . | |. |.|.... . |..| . . . . . LLQFWIQQCHNWNHWLPEWMIWQILVDICQGLHHIHSNCGMVHMDIKPENIFISKKMNCNQIVNNDQQNNNDWWFNMMCKIGDFGHVTDMNS------NN NNVPQ-----GIYISPELLNDMYQQQYNPVYNQQKADVFSIGMCMLHAA ||. | . |..||.|.. | . |||.||.|. ....| NNPHQEQEGDSRYMAPEILQG-----YYHYTHLYKADIFSLGITIYELA |
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| Kinase | n169.AA | Ciliate-E1 | 27-222 | 17 | 4e-06 | 16.38 | In-house | 1-202 (202) | Show / Hide |
Range on Protein: 27-222
Range on HMM: 1-202/202
Sequence Identity: 17% (38 aa)
LNHPSFGDIQILKDKSSD-NQVGLKEFNLT---DESEFAKTIEKFK-PKLALD-NPNLIKLHNCIQNKESQFCSTFFKVYLVFEYVKNTLEQEVQ-----
. . ||... . | ... ||| .| .|. .. .| . |.. . .. . . ..|.. ..|. .....| ...||... .|... |
IGNGSFSIVFKAKQQNNNYNQVAQKIINCCFNYNQNHFQDEIKEYYKIMK-FKKECYIIQIIDYIKIDQNYIC------IIIFECCCCSLKDYLQNHNRL
---ERSKDQKQPFSEEEMWNILTSCIQGAHFLYQNKLSNNNIRPSTIYITSNGIVKLADPTLFS-----QQGLYPAALSSPNNVPQGIYISPELLNDMYQ
. ... |..... .| |.| |.|... .| |. | |...|. ...| . . |. . . |. | .||. . ...
EYWQQCQQNQNQFTFQQKMQIIFQLIDGLIELHQYNIIHRDIKPQNILINNQGNYVYCDFGISKFLKNNQNQQCQYKGYTHYYYPPEQYNCPEQ-EHNKN
QQYNPVYNQQKADVF
|..| .| |..
QKIN-----YKSDIY
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| Kinase | n169.AA | Ciliate-E2-Unclassified | 21-171 | 16 | 9e-06 | 16.01 | In-house | 1-190 (352) | Show / Hide |
Range on Protein: 21-171
Range on HMM: 1-190/352
Sequence Identity: 16% (33 aa)
FQQQEKLNHPSFGDIQILKDKSSDNQV--------------GLKEFNLTDESEFAKTIEKFK-------------PKLALDNPNLIKLHNCIQNKESQFC
. ...... .||... ...|. . |. ..... ... .|.... | . | ...|...|.. | |.|.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQ----
STFFKVYLVFEYVKN-TLEQEVQERSK------------DQKQPFSEEEMW-----NILTSCIQGAHFLYQNK-LSNNNIRPSTIYITSNG---IVKLAD
..|.| ||... .|.| ..|.| |.. |.|... ... .|| .| ... .| |. | ...|| .|..|
----NIYIVMEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIID
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| Kinase | n169.AA | CAMK | 73-129 | 18 | 3.6e-05 | 11.82 | In-house | 95-180 (425) | Show / Hide |
Range on Protein: 73-129 Range on HMM: 95-180/425 Sequence Identity: 18% (17 aa) LDNPNLIKLHNCIQ------------NKESQFCSTFFK----VYLVF---EYVKNT-LEQEVQERSKDQKQ--------------PFSEEE || ||.|||. .. . . | .| . .|.|. ||. . | ... .. ..... |.|.| LDHPNIIKLYEVYEDPHYFKNTNDYET-SKQ---VF-TKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTERE |
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| Kinase | n169.AA | CMGC | 76-129 | 26 | 4.3e-05 | 11.67 | In-house | 98-163 (513) | Show / Hide |
Range on Protein: 76-129 Range on HMM: 98-163/513 Sequence Identity: 26% (18 aa) PNLIKLHNCIQNKESQ-----FCST----FFKVYLVFEYVKNTLEQEVQERSKD----QKQPFSEEE .|..||..... |.|. . .. | ..||||||. ..| | .. ..| ...|.|| . NNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-H |
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| Kinase | n169.AA | CDKL | 98-171 | 29 | 4.9e-05 | 13.16 | In-house | 72-142 (286) | Show / Hide |
Range on Protein: 98-171 Range on HMM: 72-142/286 Sequence Identity: 29% (22 aa) KVYLVFEYVKNTLEQEVQERSKDQKQPFSEEEMWNILTSCIQGAHFLYQNKLSNNNIRPSTIYIT-SNGIVKLAD | .|||||. .|. | .| . . |. ... ... .|. ... .| | |.|| .||.||| | KLHLVFEYCDHTVLHELEE----YPNGVDEHVVRKYMWQILKAINFCHKHNCIHRDIKPENILITPKNGQVKLCD |
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| Kinase | n169.AA | CAMKK | 73-107 | 27 | 0.000173 | 9.67 | In-house | 84-113 (396) | Show / Hide |
Range on Protein: 73-107 Range on HMM: 84-113/396 Sequence Identity: 27% (10 aa) LDNPNLIKLHNCIQNKESQFCSTFFKVYLV-FEYVK ...|| .||. .|.. ... |.|.| .||.. CNHPNIVKLYEVIDDPQND------KIYMVQMEYCE |
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| Kinase | n169.AA | TAO | 122-171 | 36 | 0.000305 | 9.44 | In-house | 93-142 (254) | Show / Hide |
Range on Protein: 122-171 Range on HMM: 93-142/254 Sequence Identity: 36% (18 aa) KQPFSEEEMWNILTSCIQGAHFLYQNKLSNNNIRPSTIYITSNGIVKLAD |.|. |.|. | .|| ..| . |. |. . | .| .|.||||| KKPMQEVEIAAICHGALQGLRYLHSHKMIHRDIKAGNILLTEHGQVKLAD |
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| MORN | n169.AA | MORN | 974-994 | 42 | 3e-06 | 27.57 | Pfam | 1-21 (23) | Show / Hide |
Range on Protein: 974-994 Range on HMM: 1-21/23 Sequence Identity: 42% (9 aa) FDGEWRENKMHGKGILSYASG ..|||...||||.|......| YEGEWKNGKMHGHGVYTWPDG |
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| MORN | n169.AA | MORN | 951-973 | 47 | 9e-06 | 25.71 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 951-973 Range on HMM: 1-23/23 Sequence Identity: 47% (11 aa) YEGEKLNGMRHGRGKFYYQDGGL |||| ||..||.|.... ||. YEGEWKNGKMHGHGVYTWPDGDR |
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| MORN | n169.AA | MORN | 949-970 | 45 | 1e-05 | 26.3 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 949-970 Range on HMM: 1-22/22 Sequence Identity: 45% (10 aa) SKYEGEKLNGMRHGRGKFYYQD ..|||| ||.|||.|.... . DRYEGEWHNGKRHGHGVYWWAN |
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| MORN | n169.AA | MORN | 972-993 | 36 | 2.3e-05 | 25.06 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 972-993 Range on HMM: 1-22/22 Sequence Identity: 36% (8 aa) GLFDGEWRENKMHGKGILSYAS .|||...|.||.|.. .|. DRYEGEWHNGKRHGHGVYWWAN |
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| MORN | n169.AA | MORN | 996-1017 | 31 | 0.000311 | 20.62 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 996-1017 Range on HMM: 1-22/22 Sequence Identity: 31% (7 aa) PAYDGDWVDDKFEGFGILYNEN |.|.|...|. |.|... | DRYEGEWHNGKRHGHGVYWWAN |
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| MORN | n169.AA | MORN | 998-1014 | 35 | 0.004243 | 16.01 | Pfam | 1-17 (23) | Show / Hide |
Range on Protein: 998-1014 Range on HMM: 1-17/23 Sequence Identity: 35% (6 aa) YDGDWVDDKFEGFGILY |.|.|...|..|.|... YEGEWKNGKMHGHGVYT |
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| MORN | n169.AA | MORN | 1040-1062 | 30 | 4.8e-05 | 23.07 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 1040-1062 Range on HMM: 1-23/23 Sequence Identity: 30% (7 aa) YEGQFKDDNKEGYGTLFLSNGEK |||..|.. ..|.|.. ..| . YEGEWKNGKMHGHGVYTWPDGDR |
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| MORN | n169.AA | MORN | 1038-1059 | 27 | 0.000484 | 19.18 | SMART | 1-22 (22) | Show / Hide |
Range on Protein: 1038-1059 Range on HMM: 1-22/22 Sequence Identity: 27% (6 aa) TKYEGQFKDDNKEGYGTLFLSN .|||..... . |.|.. .| DRYEGEWHNGKRHGHGVYWWAN |
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| MORN | n169.AA | MORN | 1063-1085 | 21 | 0.709116 | 7.94 | Pfam | 1-23 (23) | Show / Hide |
Range on Protein: 1063-1085 Range on HMM: 1-23/23 Sequence Identity: 21% (5 aa) FVGTFYKDFVNGAGTFYTLNGDV . |.. ... .| |... .||. YEGEWKNGKMHGHGVYTWPDGDR |
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