Gene CC1G_08126 (C.cinerea)

CC1G_08126

Species: C.cinerea
Alias: CC1G_08126
External Links:
Annotation:

Classification

Group: Atypical
Family: PIKK
Subfamily: ATR

Sequence

Name Sequence Type Origin Length Description Download
CC1G_08126.AA Protein None 2345 None Fasta, JSON
CC1G_08126.NA RNA None 7038 None Fasta, JSON
CC1G_08126.kin_dom Protein Kinase Domain None 267 None Fasta, JSON

Protein domain

Protein domains of CC1G_08126.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HEAT CC1G_08126.AA HEAT 527-557 25 0.003278 14.98 Pfam 1-31 (31) Show / Hide 
Range on Protein: 527-557
Range on HMM: 1-31/31
Sequence Identity: 25% (8 aa)

VLEMITRGVTDDDRAVRVQAGLTLQAVVEFY
.|... .. .|.|  || .|  .| ...|..
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
UME CC1G_08126.AA UME 815-921 29 3.1e-22 81.12 SMART 1-115 (115) Show / Hide 
Range on Protein: 815-921
Range on HMM: 1-115/115
Sequence Identity: 29% (34 aa)

PSEFLATQMLGIMSKIIDTLQDVHGKKSVEAKEQIIRSIGVFIS-LVGPPIHSLSSQ---IMAIFQTSLSVAELAEVTLESWHEYLVTIDS---KD-LGP
  .||. ..|||| .. ... |.||||... |....|||.  |. ..|. | |   |   |||  || | . || . ... ||  . . .     . .||
FADFLQDHFLGIMQWFNMIMHDSHGKKPYYEKKRALRSIEFMIKYMMGKHISSFRPQIIQIMACLQTALEIPELRHHCCRCWHCFIKHLNEVSCEHYIGP

HLGSTCSAFVSAWPN
 .. . ..... || 
LIDQIFAIILPYWPT
UME CC1G_08126.AA UME 816-921 29 5.4e-20 69.79 Pfam 2-112 (112) Show / Hide 
Range on Protein: 816-921
Range on HMM: 2-112/112
Sequence Identity: 29% (33 aa)

SEFLATQMLGIMSKIIDTLQDVHGKKSVEAKEQIIRSIGVFIS-LVGPPIHSLSSQIMAIFQTSLSVA--ELAEVTLESWHEYLVTIDS--KDLGPHLGS
 .||. ..|||.... ... |..|..... | ..||||.  |. . |. | |   ||||  |. |     || . ....||  . | |    .||| ...
ADFLQDHFLGIITRFSMVMHDFQGRQPYFEKKRCIRSIEEMIKYMCGKHISSARPQIMACLQSALEIPEEELRYHCFRCWHVFIQTLDEVPEHLGPLIDQ

TCSAFVSAWPN
| .. .. |. 
TFVIIIPYWDT
DUF3385 CC1G_08126.AA DUF3385 1056-1069 71 0.000664 15.54 Pfam 35-48 (181) Show / Hide 
Range on Protein: 1056-1069
Range on HMM: 35-48/181
Sequence Identity: 71% (10 aa)

CIGILGALDPYRFQ
|.|||||||||...
CMGILGALDPYKHK
FAT CC1G_08126.AA FAT 1479-1800 13 1.8e-14 48.71 Pfam 10-408 (408) Show / Hide 
Range on Protein: 1479-1800
Range on HMM: 10-408/408
Sequence Identity: 13% (56 aa)

MVGAWDD--VEALVNTAD------------STSV-----PVMMAKVMLAM--RKGDPQ--AISDALSLARLTLGAPISA-AGVNGYARSYEAALSLHHLY
..| ||.   .  . . .            . |           .  |..  .... .    .   . ||  |   ..|      | | | .  ... | 
RLGQWDETYMDEYISVMKKLLGEDQLTFIDEDSPDEPTWDRSFFQAILCLYKHHNQFDTYEAHRYIDKARQLLDTEWTACLPGESYNRHYPVMVRVQMLA

ELELIHNTTRNLPSS--------STRRKQALTRLSSILADRLENV-LPTFRNLEPILSTRRIGFS-----LMPGTSPDLVKEVGKAWLSSAKVARKAGHW
||| |    . ...         . ..|.          .|| ..  . ..  ..||. |.. ||     .|    ... .|  . |. .|...||.|. 
ELEEIIQYKSQCNQNNAQNLDNSPEKQKHM----RQTWWKRLPGCKQRNVEVWQRILTWRQHVFSKINQRYMNSFCYRGPHEDMWMWIKFANLCRKHGRM

PTAYSAILQARQSG----------TPLWFLESAKLMKASGDFIMKAVRELE---S-HMQSLGLISSGNVLDLTL------------DDEVVNTKH-KLFL
  .. ........            | |  ...|.| |.|.   .| ..|.   | |||.    .. | .   |              .    .  . ..
QLCEKTLKMLYTYDPSEEDWHPRAPPQWTYAYLKYMWATGQQ-QEAFQHLREFTSCHMQHDLGVHNNNEIN-GLTYNLEVINNTNLEYFYTKLLAMRCYH

WRARWMSES--------GRFDGTPLLEAFKRATELDKRWES-SHFYFGNFYDASAKDLKPTDA--------RRLKMNMHMLRNYSRATRYGTK-FIYQTI
 ...|. .         .. .    |.....||..|..|.   ... . ....  . ..             .. . .  .... .. ... .  ..| .
KQGMWQWKLYEEQYMNWNQEQKDEILQCYMTATHFDPQWYKKAWHNWALYNFEVFQHYQCQPQREEQNYTHMIIQHVVPAVKCFFHSIALSQGSNSRQDT

PRLLT
.|||.
LRLLW
HEAT CC1G_08126.AA HEAT 1839-1869 9 8.835422 3.1 Pfam 1-31 (31) Show / Hide 
Range on Protein: 1839-1869
Range on HMM: 1-31/31
Sequence Identity: 9% (3 aa)

AFPQIVSRVCHPVDKVYNLVSQLIVSIIQEY
 .| ...  ..|...|   . . ...... .
ILPHLLKCLNDPDWEVREAACWCLGQLCEHC
Kinase CC1G_08126.AA PIKK 1985-2251 37 1e-114 387.42 In-house 1-290 (290) Show / Hide 
Range on Protein: 1985-2251
Range on HMM: 1-290/290
Sequence Identity: 37% (108 aa)

TFKEFSDEIDVMRSMARPRKIWITGSDGGEYIMLIKPKDDLRKDARLMDFDTIINRLLKANADARRRKLYIRTYAVVPLNEECGCIEWVQNTSPLRPILF
  . . . . || .  .|.|| | |.|| ||..| |...|||.|.|.| .  ..|..|  ..  ..|.| ||||.|.|.. .|| ||||.|...|..|. 
RIRFMDRMVTVMAHKQKPKKIYIRGHDGKEYPYLCKGHEDLRQDQRVMQLFQLMNTCLQKDPECQKRHLHIRTYSVIPMSQRCGLIEWVDNCVTLKEIYK

KYYE------ARRIKT----------------WTAELEAQCNKIKDAQAADAGNIFVKKILPMFPPVFHQWFIETFPDPSAWLENRTNYARTAAVMSIVG
....      .  .                   .  ...||.. ...   .   .| .   . .|..|. || ..|||| .|.| |.||.|. |||..||
QWCQKKHIRHEQEAQMNYQTCMYRDWLKQMSYYKHQMQQQCMMYQHWPLHEKVEVFREQMQNTPPDMFKKWFWRKFPDPEIWWERRENYTRSYAVMCMVG

WILGLGDRHCENILLDVITGDAVHIDFNCLFE-KGKVLLTPERVPFRLTQNIVDGLGVTGVEGMFRIACELTMDLLRNNMDSLMSVLDAF
.|||||||| |||..| .||. |||||.|.|| ... | .|| ||||||.|.|...|..|||| || .|| .| ..|.. ..||.|...|
YILGLGDRHPENIMIDMQTGEIVHIDFGCCFESAMQRLPVPEKVPFRLTRNMVNAMGPMGVEGVFRRCCEHVMMCMRQHRETLMTVCEVF
Kinase CC1G_08126.AA ATR 1985-2251 46 6.4e-107 361.52 In-house 2-267 (267) Show / Hide 
Range on Protein: 1985-2251
Range on HMM: 2-267/267
Sequence Identity: 46% (123 aa)

TFKEFSDEIDVMRSMARPRKIWITGSDGGEYIMLIKPKDDLRKDARLMDFDTIINRLLKANADARRRKLYIRTYAVVPLNEECGCIEWVQNTSPLRPILF
    | | .... |. .|.|| . ||||  |||. ||||||||| |.|.|. .||....  .. ||| . .|||||.|||..|. ||||.||  ||||| 
YIAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCREMRFNELINFCNRKDYEERRRFYHMRTYAVIPLNDQCCIIEWVNNTATLRPILD

KYYEARRIKTWTAELEAQCNKIKDAQAADAGNIFVKKILPMFPPVFHQWFIETFPDPSAWLENRTNYARTAAVMSIVGWILGLGDRHCENILLDVITGDA
| .. ....    .|  ||   | ..  .   .| . .||  ||.||.||  .||||  |   | || |. ||...||.|.|||||| .|||.| |.|. 
KLWKEKKQYMQFYQLR-QCMDKKSREEWEKQKVFREFLLPRHPPIFHDWFNRRFPDPQQWYSSRENYCRSYAVWCMVGYIIGLGDRHTDNILIDKINGEC

VHIDFNCLFEKGKVLLTPERVPFRLTQNIVDGLGVTGVEGMFRIACELTMDLLRNNMDSLMSVLDAF
||.|.||.| .|. .  || ||||||.|.| |.|  . .|.|| ||| .| ..|...| .|||.|.|
VHVDYNCIFNSGEQFEVPEIVPFRLTHNMVFGMGPMKTYGLFRRACEVIMMCMRDHRDDIMSVWDCF
Kinase CC1G_08126.AA PI3Kc 2016-2314 27 4.8e-87 296.4 SMART 1-336 (336) Show / Hide 
Range on Protein: 2016-2314
Range on HMM: 1-336/336
Sequence Identity: 27% (94 aa)

IMLIKPKDDLRKDARLMDFDTIINRLLKANADARRRKLYIRTYAVVPLNEECGCIEWVQNTSPLRPILFKYYEARR----IKTWTA--------------
 .. |..||||.|.| | .  ..|.... .. .|||.|..|.|...|....|| |||| |. .|..|. ||.. ..    .. |.               
AVIFKCGDDLRQDMRMMQMFRLMNKIWQKDKECRRRDLHMRPYKCIPTGPKCGMIEWVPNCETLHQIQKKYHKWKKMPMDYHQWFMFDMLVPEIQKNMYM

--ELEAQCNKIKDAQAAD---AGNIFVKKILPMFPPVFHQWFIETFPDPS-AWLENRTNYARTAAVMSIVGWILGLGDRHCENILLDVITGDAVHIDFNC
  ... .| .....| ..       | ... | .|||...||.|.||||. .| | |.|..|  |....|..|||.||||..||.||  || ..||||..
MIWHQQACHWMMMYQHMTHMEWLKYFEGATCPFKPPVLYDWFWEHFPDPNEDWWEARDNFTRSCAGYCMVTYILGIGDRHNDNIMLDMKTGHCFHIDFGH

LFEKGKVLLTP-----ERVPFRLTQNIVDGLG----VTGVEGMFRIACELTMDLLRNNMDSLMSVLDAFIHDPL-VEWEDE-KRKQENRSRRSAQQVPVT
.|..|......     ||||||||...|.. |    ..|..| ||  |. .. ..| .....|... ....||.  .|  . |...  |.|   .   ..
IFGHGPKKPGFKHHHRERVPFRLTHDMVYVMGGGGKPSGYFGYFRTCCCRAYRAMRKHSNLIMNLFEMMVYDPIMPCWRMMEKDIKYLRQRFRLDH--LS

TTNIAKNALN----DIKKKLEGRFTPYTDSQFEQPEKL
  ..|. . .     . ... . .|. .  .|.   ..
DEEAAQYFMQTMCTKLIEHSNESWTTRMYWMFHNWAQY
Kinase CC1G_08126.AA PI3_PI4_kinase 2014-2261 27 4.8e-76 263.75 Pfam 1-300 (300) Show / Hide 
Range on Protein: 2014-2261
Range on HMM: 1-300/300
Sequence Identity: 27% (85 aa)

EYIMLIKPKDDLR--KDARLMDFD-----------------------TIINRLLKANADARRRKLYIRTYAVVPLNEECGCIEWVQNTSPLRPILFKYYE
.| .. | .||||  .|.|.| .                        ...|...| ..  |||.. ...| ..|....|| |||| |. ....|. .|..
WYPFIFKGGDDLRCRQDMRMMQMICVFKPKDEEPYANNPNKWTMWQHRLMNKCWKKDGCDRRRNMQMQPYRCIPTGPWCGMIEWVPNCTTFHEIPRTYMV

ARRIKT-----------WTAELEAQCNKIKDAQAADAGNIFVKKILPMFPPVFHQWFIETFPDP-SAWLENRTNYARTAAVMSIVGWILGLGDRHCENIL
 ...|            |.. ...         . .   .| ..| . ..|...|||....||.  .|.| |.|..|  |.|..|..|||.||||..||.
KCKHKHFNKEHKMWMKMWPDWWHLM--------RMQKVEVFEMRIMKTPKPGLYQWFWKHNPDAYEEWWEARDNFVRSCAGMCVVDYILGNGDRHNDNIM

L--DVITGDAVHIDFNCLFE--KGKVLLTPERVPFRLTQ------NIVDGL------GVTGVEGMFRIACELTMDLLRNNMDSLMSVL-------DAFIH
.  |  ||  .||||.. |.  |.|..  |||||||.|.      ..|...      ...| .|.||  |. .. .|| .|...|..|       ....|
VKDDKTTGHLFHIDFGHCFPHWKMKHFHKPERVPFRWTHWPQAKKPMVHAMGGYISLDPSGDYGWFRDYCWHAYRALRRHMNLCMNLLKKAVMRGECMVH

DPLVEWED
|.|..| .
DGLPMWRS
Kinase CC1G_08126.AA ATM 2126-2259 52 1.9e-55 175.49 In-house 115-248 (304) Show / Hide 
Range on Protein: 2126-2259
Range on HMM: 115-248/304
Sequence Identity: 52% (70 aa)

FPPVFHQWFIETFPDPSAWLENRTNYARTAAVMSIVGWILGLGDRHCENILLDVITGDAVHIDFNCLFEKGKVLLTPERVPFRLTQNIVDGLGVTGVEGM
| |||  . .| | ||  | | |  | |  |  ||||.||||||||  |||.     . ||||    ||.||.| ||| ||||||  ||||.|.|||||.
FQPVFRYFCMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMGITGVEGV

FRIACELTMDLLRNNMDSLMSVLDAFIHDPLVEW
||  || ||. .||  . |. . .  . ||| .|
FRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDW
Kinase CC1G_08126.AA FRAP 2144-2261 48 1.1e-44 154.77 In-house 133-251 (251) Show / Hide 
Range on Protein: 2144-2261
Range on HMM: 133-251/251
Sequence Identity: 48% (59 aa)

WLENRTNYARTAAVMSIVGWILGLGDRHCENILLDVITGDAVHIDFNCLFEKGKVLLT----PERVPFRLTQNIVDGLGVTGVEGMFRIACELTMDLLRN
|.| |||| |  |.||..|.||||||||  ||.|.  ||  |||||   ||   | ..    ||..|||||  .|  . ..|.|| .|..||| |. .| 
WFERRTNYTRSLATMSMAGYILGLGDRHPSNIMLQRYTGKIVHIDFGDCFE---VAMRREKFPEKIPFRLTRMLVNAMEACGIEGNYRNTCELVMKVIRE

NMDSLMSVLDAFIHDPLVEWED
. .|.| ||.||. |||  |  
HKESVMAVLEAFVYDPLFYWRL
Kinase CC1G_08126.AA SMG1 2141-2203 55 1.1e-24 78.54 In-house 180-242 (242) Show / Hide 
Range on Protein: 2141-2203
Range on HMM: 180-242/242
Sequence Identity: 55% (35 aa)

PSAWLENRTNYARTAAVMSIVGWILGLGDRHCENILLDVITGDAVHIDFNCLFEKGKVLLTPE
|  |      |||  ||||.||.|.|||||| .|.|.|. ||. ||||..  ||||| |  ||
PDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYPICFEKGKKLNVPE
Kinase CC1G_08126.AA DNAPK 2141-2261 31 1.7e-19 67.49 In-house 180-301 (301) Show / Hide 
Range on Protein: 2141-2261
Range on HMM: 180-301/301
Sequence Identity: 31% (39 aa)

PSAWLENRTNYARTAAVMSIVGWILGLGDRHCENILLDVITGDAVHIDFNCLFE-KGKVLLTPERVPFRLTQNIVDGLGVTGVEGMFRIACELTMDLLRN
. ..|  |  ..|. ||  | .|||| |||| .| .    .|| . |||   |   .  |  ||  |||||   .  .   .. |...      |  .| 
CETYLYLREHFIRNYAVICISHWILGIGDRHLNNFMVNMENGDIISIDFGHSFGSATQFLPVPELMPFRLTRCFINLMSPMKINGIMYQIMIHSMMAFRK

NMDSLMSVLDAFIHDPLVEWED
    |.   | || ||.. |  
DRNILTNFCDVFINDPSFDWKN
Kinase CC1G_08126.AA FRAP 2014-2093 33 1.4e-17 61.24 In-house 1-80 (251) Show / Hide 
Range on Protein: 2014-2093
Range on HMM: 1-80/251
Sequence Identity: 33% (27 aa)

EYIMLIKPKDDLRKDARLMDFDTIINRLLKANADARRRKLYIRTYAVVPLNEECGCIEWVQNTSPLRPILFKYYEARRIK
||. |.| ..|.| | | |    .|||||. |...... | |. |...||  . | | ||..   |. ..  | .. .|.
EYHFLLKGHEDIRQDERVMQLFGLINRLLHNNPETQKKNLSIQRYSIIPLSMNTGLIGWVHHCDTLHILIRDYRKKYHIR
Kinase CC1G_08126.AA ATM 2017-2078 45 3.1e-15 44.75 In-house 2-63 (304) Show / Hide 
Range on Protein: 2017-2078
Range on HMM: 2-63/304
Sequence Identity: 45% (28 aa)

MLIKPKDDLRKDARLMDFDTIINRLLKANADARRRKLYIRTYAVVPLNEECGCIEWVQNTSP
 |.| .||||.|| .     . | ||. | . |.||| | || ||||    | .||   | |
QLVKGRDDLRQDAVMQQVFQMCNTLLQRNTETRKRKLTICTYKVVPLSQRSGVLEWCTGTIP
Kinase CC1G_08126.AA DNAPK 1985-2085 33 6.1e-15 50.65 In-house 3-103 (301) Show / Hide 
Range on Protein: 1985-2085
Range on HMM: 3-103/301
Sequence Identity: 33% (34 aa)

TFKEFSDEIDVMRSMARPRKIWITGSDGGEYIMLIKPKDDLRKDARLMDFDTIINRLLKANADARRRKLYIRTYAVVPLNEECGCIEWVQNTSPLRPILF
    | . . || |. ||..| | | |  |   ..|   ||| | |      . |  .        | |  ||| ..|.    | |||| ||. |. || 
RIAGFDERVTVMASLRRPKRIIIRGHDEREHPFCYKGIEDLRQDQRIEQLFQVMNNIFEYDPQCQQRELQLRTYNIIPMTNRLGLIEWVDNTVVLKDILN

K
.
N
Kinase CC1G_08126.AA FATC 2313-2345 48 1.1e-12 43.65 Pfam 1-33 (33) Show / Hide 
Range on Protein: 2313-2345
Range on HMM: 1-33/33
Sequence Identity: 48% (16 aa)

KLLSTKNLVEALINEASNPMNLSKMYPGWAPWN
. ||.   |. ||.||..| ||..||.||.|| 
EPLSVEQQVDRLIQEATDPENLCQMYIGWCPWW
Kinase CC1G_08126.AA SMG1 1993-2079 33 1.2e-12 38.03 In-house 1-87 (242) Show / Hide 
Range on Protein: 1993-2079
Range on HMM: 1-87/242
Sequence Identity: 33% (29 aa)

IDVMRSMARPRKIWITGSDGGEYIMLIKPKDDLRKDARLMDFDTIINRLLKANADARRRKLYIRTYAVVPLNEECGCIEWVQNTSPL
| ..    .|.|.   ||||  |  | |  .||  | |.| |  |.| .          .   | |.| ||    | | ||    ||
ITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPL