Gene CC1G_06302 (C.cinerea)

CC1G_06302

Species: C.cinerea
Alias: CC1G_06302
External Links:
Annotation:

Classification

Group: Atypical
Family: PIKK
Subfamily: PI3K

Sequence

Name Sequence Type Origin Length Description Download
CC1G_06302.AA Protein None 852 None Fasta, JSON
CC1G_06302.NA RNA None 2559 None Fasta, JSON
CC1G_06302.kin_dom Protein Kinase Domain None 293 None Fasta, JSON

Protein domain

Protein domains of CC1G_06302.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PI3K_C2 CC1G_06302.AA PI3K_C2 55-197 36 9.7e-53 186.32 Pfam 1-168 (168) Show / Hide 
Range on Protein: 55-197
Range on HMM: 1-168/168
Sequence Identity: 36% (61 aa)

TLSDLYVTCQLI--ADNKPLTIPY-RTPFKAFK----NSYTWNEWITFP-VRYCDLPASSQITFTVWDIGGPRTA----------VPVGGSTFRLFGK-K
. .|.||.||.    ..|||. |  .|..|.|.    ....|||||||| ..||||| ......|.|.| ..  .          .|.|.....||.. |
PYMDFYVECQVYDGHGGKPLCKPVQSTSYKPFNNHFFPRWNWNEWITFPQIQYCDLPRDARLCITIWEIYCKKKSESNMNEQNKKCPIGWCNLPLFDHEK

WTLRRGKHRLLL-WPGVEADGSVETTTP--SKLAIRDEMGRLEKLVKKYERGDLPK---NDWLDTMAF
 .||.|.|.| . ||.........|.||  .... ||||.|||||.||.|.|. ..    |||| ..|
CMLRCGMHKLHMTWPSKPPCPMFPTHTPWKVPRHWRDEMNRLEKLLKKHEWGQMQRNPRCDWLDFLTF
PI3K_C2 CC1G_06302.AA PI3K_C2 23-132 28 1.5e-26 95.47 SMART 1-133 (133) Show / Hide 
Range on Protein: 23-132
Range on HMM: 1-133/133
Sequence Identity: 28% (38 aa)

FRISQLEGIRKPK------SFTEVLENPDLRFHGVQQATLSDLYVTCQLIAD-NKPLTIPYRTPF----KAFKNS-----YTWNEWITF-PVRYCDLPAS
. |. |. . .|.      ..   .....| . . .. . .||||.|||  . .|... | ||..    |.| |.     ..||||.|| |..||||| .
VKICSLWCCNRPFVFLPHEITIYCIHDIMLNWSQDYESSCVDLYVECQLYHGMGKQFCCPVRTSYHQYVKHFFNRTFHLFWKWNEWLTFFPIQYCDLPRM

SQITFTVWDIGG-PRTAVPV-----GGSTFRLF
... .|.||.   .....|.     |.|.|..|
ARLCITIWDVYDDSKKSEPFFSRCVGWSNFDWF
PI3Ka CC1G_06302.AA PI3Ka 302-507 38 1.4e-70 241.69 SMART 1-232 (232) Show / Hide 
Range on Protein: 302-507
Range on HMM: 1-232/232
Sequence Identity: 38% (91 aa)

DRELKP--NAKIRDELTHILNYSPSQQLTSEEKDLIWKFR-FYLARDKRGLT-----KFLKSVTWRDSSEVKQAVEELLPQW--TEIDTDDALELLGPST
|..|||  | ..||.|  |..| |...||.|||||||||| .||   .. |.     |||..| | ...|||||  .|. ||  ..|| .||||||.|. 
DYDLKPRWNEEERDQLEDIMKYPPTYELTEEEKDLIWKFRHYYLTNHPKALPSMCFPKFLRCVNWSWADEVKQAY-QLMHQWWWPPIDPEDALELLDPKF

VD---SRVRAFAVKQLSRADDDELLGYLLQLVQALKFE----------------SAASEQRSSRTTTSAISYDDSGLTDFLIARGVRNPIMGNRLYWYLM
 |     ||..||. | ...||||| ||||||||||.|                |       | |. .. .| || |..||. | ..||  |...|||| 
PDYNCPHVRQYAVQCLEQMSDDELLHYLLQLVQALKYENFDHIKHHFCEFDQDQS------MSMTKEEDGPYHDSPLCRFLLQRALCNPRIGHFFYWYLK

VEV----ALEDRVMAKMYGRVVFKFMNKILEAEGGSERR
.|.    .|.|  .....|..   .......     ...
SEMYDHCQLHDPHYCQRFGMLLEMYCRGCCGHHMRHLFK
PI3Ka CC1G_06302.AA PI3Ka 303-497 36 3.8e-65 225.71 Pfam 1-202 (211) Show / Hide 
Range on Protein: 303-497
Range on HMM: 1-202/211
Sequence Identity: 36% (78 aa)

RELKP-NAKIRDELTHILNYSPSQQLTSEEKDLIWKFR-FYLARDKRGLT------KFLK-SVTWRDSSEVKQAVEELLPQ--WTEIDTDDALELLGPST
..||| | |.|..|. |..| |. |||.|||.|||||| ... . .. |.      |||. .|.|.|...|.||  .|..   |..|| .||||||... 
KDLKPVNNKERKQLEQIIKYDPLSQLTAEEKCLIWKFRHYCCMNNPKALPLMCVGPKFLQLCVKWHDYDQVAQAY-QLMDCRVWPPIDPCDALELLDCNF

VD--SRVRAFAVKQLSR-ADDDELLGYLLQLVQALKFESAASEQRSSRTTTSAISYDDSGLTDFLIARGVRNP-IMGNRLYWYLMVEV----ALEDRVM-
 |  . ||..||| | . ..||||| ||||||||||.|                 ..|| |. ||. |. .|. . |. ..||. .|.     ..|.   
PDNCPMVRQYAVKCLESYMSDDELLCYLLQLVQALKYENF------------DEPFHDSYLSRFLLWRAWQNRQRIGHFFFWYMKSEMYKDDEGHDKDYI

AKMYGRVVFKFMNKI
.. .|.. . .  ..
CQRFGVLLESYCREC
Kinase CC1G_06302.AA PI3Kc 599-849 28 5.3e-100 339.45 SMART 1-336 (336) Show / Hide 
Range on Protein: 599-849
Range on HMM: 1-336/336
Sequence Identity: 28% (98 aa)

PVIFKDGDDMRQDQLVIQLFTLMDQLLRKE----NLDLKLSPYDVLATGPLQGMVQFIP-SKTIAAIVS-------------------------------
.|||| |||.|||....|.| ||. ...|.    ..||.. || ...|||  ||....| ..|.. | .                               
AVIFKCGDDLRQDMRMMQMFRLMNKIWQKDKECRRRDLHMRPYKCIPTGPKCGMIEWVPNCETLHQIQKKYHKWKKMPMDYHQWFMFDMLVPEIQKNMYM

-------------------------EHGNVL--------NYLRVNNPDEGSVGTSGVEPSVIDTFVRSCAGYCVVTYILGVGDRHLDNLLIA-PDGHFFH
                         ..|..         .... ..||..     .. ....|.|.|||||||.||||||.||||.||...   .|| ||
MIWHQQACHWMMMYQHMTHMEWLKYFEGATCPFKPPVLYDWFWEHFPDPN-----EDWWEARDNFTRSCAGYCMVTYILGIGDRHNDNIMLDMKTGHCFH

VDFGYILGRDPKPFPP--------AVKVCKEMVDGMG--GAQSPHYMRFKNYCFTAFSILRKSANLILNLVALMVDANI-PDIKHR-DVHEQIQEKFRLD
.|||.|.|..||....          . ...||..||  |..|... .|. .| .|. ..||..|||.||...||...| |...   .  ......||||
IDFGHIFGHGPKKPGFKHHHRERVPFRLTHDMVYVMGGGGKPSGYFGYFRTCCCRAYRAMRKHSNLIMNLFEMMVYDPIMPCWRMMEKDIKYLRQRFRLD

-LSEEDAIKHFET-----LLNET--SYFTVVLDRIHDLAQY
 ||.|.|...|.      |....  | .| . . .|..|||
HLSDEEAAQYFMQTMCTKLIEHSNESWTTRMYWMFHNWAQY
Kinase CC1G_06302.AA PI3_PI4_kinase 597-802 25 4.9e-77 267.04 Pfam 1-300 (300) Show / Hide 
Range on Protein: 597-802
Range on HMM: 1-300/300
Sequence Identity: 25% (79 aa)

EYPVIFKDGDDMR--QDQLVIQLF-----------------------TLMDQLLRKENLDLK----LSPYDVLATGPLQGMVQFIPSK-TIAAIVSEH--
.||.||| |||.|  ||....|..                       .||. ...|...|..    . || ...|||  ||....|.. |.. | ...  
WYPFIFKGGDDLRCRQDMRMMQMICVFKPKDEEPYANNPNKWTMWQHRLMNKCWKKDGCDRRRNMQMQPYRCIPTGPWCGMIEWVPNCTTFHEIPRTYMV

------------------------------------------GNVLNYLRVNNPDE-GSVGTSGVEPSVIDTFVRSCAGYCVVTYILGVGDRHLDNLLI-
                                          .  ..... .|||. .  ..      ..|.|||||||.|||.||||.||||.||... 
KCKHKHFNKEHKMWMKMWPDWWHLMRMQKVEVFEMRIMKTPKPGLYQWFWKHNPDAYEEWWE------ARDNFVRSCAGMCVVDYILGNGDRHNDNIMVK

--APDGHFFHVDFGYILG-----RDPKPFPPAVKVCK------EMVDGMGG----AQSPHYMRFKNYCFTAFSILRKSANLILNLV-------ALMVDAN
   ..|| ||.|||....     ...||...  . ..      .||..|||     .|..| .|. ||..|. .||. .||..||        ..||...
DDKTTGHLFHIDFGHCFPHWKMKHFHKPERVPFRWTHWPQAKKPMVHAMGGYISLDPSGDYGWFRDYCWHAYRALRRHMNLCMNLLKKAVMRGECMVHDG

IPDIKH
.|... 
LPMWRS
Kinase CC1G_06302.AA ATR 692-792 30 8e-11 32.67 In-house 165-267 (267) Show / Hide 
Range on Protein: 692-792
Range on HMM: 165-267/267
Sequence Identity: 30% (33 aa)

DTFVRSCAGYCVVTYILGVGDRHLDNLLIAP-DGHFFHVDFGYILGR-----DPKPFPPAVKVCKEMVDGMGGAQSPHYMRFKNYCFTAFSILRKSANLI
. ..|| | .|.| ||.| |||| ||.||    |   |||.  | ..      |   |   .. . || |||  ..  |  |.  |     ..|.  . |
ENYCRSYAVWCMVGYIIGLGDRHTDNILIDKINGECVHVDYNCIFNSGEQFEVPEIVP--FRLTHNMVFGMGPMKT--YGLFRRACEVIMMCMRDHRDDI

LNLVALM
. ..   
MSVWDCF
Kinase CC1G_06302.AA PIKK 568-629 35 5.5e-09 29.23 In-house 1-62 (290) Show / Hide 
Range on Protein: 568-629
Range on HMM: 1-62/290
Sequence Identity: 35% (22 aa)

VTGIIPEKSSVFKSNLYPLLLYFQCSDGSEYPVIFKDGDDMRQDQLVIQLFTLMDQLLRKEN
    ...   | ...  |  .|.  .|| |||  .| ..| |||| | ||| ||  .|.|..
RIRFMDRMVTVMAHKQKPKKIYIRGHDGKEYPYLCKGHEDLRQDQRVMQLFQLMNTCLQKDP
Kinase CC1G_06302.AA PIKK 694-736 45 6e-09 29.1 In-house 189-232 (290) Show / Hide 
Range on Protein: 694-736
Range on HMM: 189-232/290
Sequence Identity: 45% (20 aa)

FVRSCAGYCVVTYILGVGDRHLDNLLIAPD-GHFFHVDFGYILG
. || |  |.| |||| ||||..|..|. . |   |.|||.. .
YTRSYAVMCMVGYILGLGDRHPENIMIDMQTGEIVHIDFGCCFE
Kinase CC1G_06302.AA SMG1 690-720 54 9.7e-08 21.55 In-house 186-216 (242) Show / Hide 
Range on Protein: 690-720
Range on HMM: 186-216/242
Sequence Identity: 54% (17 aa)

VIDTFVRSCAGYCVVTYILGVGDRHLDNLLI
|   . || |   .| ||.|.||||||| ||
VTQSYARSTAVMSMVGYIIGLGDRHLDNVLI
Kinase CC1G_06302.AA ATM 694-757 36 6e-07 17.81 In-house 140-207 (304) Show / Hide 
Range on Protein: 694-757
Range on HMM: 140-207/304
Sequence Identity: 36% (25 aa)

FVRSCAGYCVVTYILGVGDRHLDNLLIAPDG-HFFHVDFGYILGRD---PKPFPPAVKVCKEMVDGMG
. || |   .| ||||.||||  |.||        |.| |         | |     .. ...|||||
YTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKILPTPETVPFRLTRDIVDGMG
Kinase CC1G_06302.AA FRAP 694-732 42 1e-06 20.63 In-house 140-179 (251) Show / Hide 
Range on Protein: 694-732
Range on HMM: 140-179/251
Sequence Identity: 42% (17 aa)

FVRSCAGYCVVTYILGVGDRHLDNLLIA-PDGHFFHVDFG
. || |   .. |||| ||||. |...    |   |.|||
YTRSLATMSMAGYILGLGDRHPSNIMLQRYTGKIVHIDFG
Kinase CC1G_06302.AA DNAPK 694-736 40 2e-06 19.01 In-house 190-233 (301) Show / Hide 
Range on Protein: 694-736
Range on HMM: 190-233/301
Sequence Identity: 40% (18 aa)

FVRSCAGYCVVTYILGVGDRHLDNLLIA-PDGHFFHVDFGYILG
|.|. |  |.  .|||.|||||.| ...   |    .|||.  |
FIRNYAVICISHWILGIGDRHLNNFMVNMENGDIISIDFGHSFG
Kinase CC1G_06302.AA FRAP 597-626 46 9e-06 17.28 In-house 1-30 (251) Show / Hide 
Range on Protein: 597-626
Range on HMM: 1-30/251
Sequence Identity: 46% (14 aa)

EYPVIFKDGDDMRQDQLVIQLFTLMDQLLR
||  . |  .|.|||  |.||| |. .||.
EYHFLLKGHEDIRQDERVMQLFGLINRLLH
Kinase CC1G_06302.AA DNAPK 594-625 40 0.000712 9.77 In-house 29-60 (301) Show / Hide 
Range on Protein: 594-625
Range on HMM: 29-60/301
Sequence Identity: 40% (13 aa)

DGSEYPVIFKDGDDMRQDQLVIQLFTLMDQLL
|  | | ..| . |.|||| . |||  |   .
DEREHPFCYKGIEDLRQDQRIEQLFQVMNNIF
Kinase CC1G_06302.AA SMG1 577-616 32 0.022917 3.47 In-house 2-41 (242) Show / Hide 
Range on Protein: 577-616
Range on HMM: 2-41/242
Sequence Identity: 32% (13 aa)

SVFKSNLYPLLLYFQCSDGSEYPVIFKDGDDMRQDQLVIQ
 .      |  | |  |||  || .||  .|.  |  ..|
TILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQ