AqueK040

Species: A.queenslandica
Alias: AqueK040
External Links:
Annotation:

Classification

Group: Atypical
Family: Alpha
Subfamily: eEF2K

Sequence

Name Sequence Type Origin Length Description Download
AqueK040.AA Protein None 564 None Fasta, JSON
AqueK040.kin_dom Protein Kinase Domain None 192 None Fasta, JSON

Protein domain

Protein domains of AqueK040.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Alpha_kinase AqueK040.AA Alpha_kinase 46-243 32 2.3e-85 290.85 SMART 1-255 (255) Show / Hide
Range on Protein: 46-243
Range on HMM: 1-255/255
Sequence Identity: 32% (84 aa)

SKSWWQDEVLIKM-QEKPFAFGAMRECYRMKKLSKFSV--QPDWHNASNYVAKCYKSEESATALKQ--------DVQLQMDAKLWGEKYNK---RNP-PK
...| ..|. .|.  .|||| ||||.||.....|....  ...|  ...|..| || . .   .          ||..|| .|.|....|.   .|| ||
DNKWTCQETCVKIKEPKPFAKGAMRWCYWGCDWSEHMHCFCHGWECVAKYFKKEYKRTWDEERYFHETLHLCLRDVEMQMMCKHWANEFNQEAQHNPCPK

KVDFFQAYLITLK---------EPLNG------------KTN-YCVEHFMEGNYIKYNSNSGYISDVNRLT------------PQAFSHFTFEKSGHQLI
|.|| ..|.. ..         ..  .            ... ...|.||||...|||.|.|. .| .| |            .|||||.|.|.|.||..
KIDFIPCYVFHFPRRIPAEYDRNIPYWFSYRTTDQMMVMCCCIFHMEPFMEGEFVKYNNNNGWVNDCMRWTTTSQRRTEMFEYCQAFSHWTYEWSNHQML

VVDIQGV----GD--LYTDPQIHTLD--MKDYGEANLGDKGMALFFSSHLCSPLC
|.|||||    ||  .|||||||| |   . .|..||| .|.. ||..| | . |
VCDIQGVIHKNGDLYYYTDPQIHTEDQNGYGFGMGNLGQEGIEKFFQTHQCNQIC

Kinase AqueK040.AA Alpha 52-243 30 2.4e-78 222.49 In-house 1-215 (215) Show / Hide
Range on Protein: 52-243
Range on HMM: 1-215/215
Sequence Identity: 30% (67 aa)

DEVLIKMQEKPFAFGAMR------ECYRMKKLSKFSVQPDWHNASNYVAKCYKSEESATALKQDVQLQMDAKLWGEKYNKRN------PPKKVDFFQAYL
....|.|  .||. ||||      .|.. .|..|.     | .. .||.. ...      . ... ... ..||...|.  .      |.| .. .. |.
QCTKIQMSSYPFMEGAMRYAMHAWDCWLHQKMVKKQHKKQWKSF-KYVWHHWIKDVERQMVCHHCVREFNQRLWEQEYTTHFNQMKPQPIKQFVHCYIYE

ITLKEPLNGKTNYCVEHFMEGNYIKYNSNSGYIS----D-VNRLTPQAFSHFTFEKSGHQLIVVDIQ-GVG-DLYTDPQIHT---LDM-KDYGEANLGDK
... .. ...  | ||..||| |.|||.|.|. .    |   ....|||||.|...|..||.|||.| ||| ...||||||.   ||  ...| .|.| .
LIH-CHNHNIKYYSVENYMEGEYQKYNNNAGWVDFLTDDNEFNQLMQAFSHWTWQYSNGQLMVVDLQWGVGEWKLTDPQIHCPAKLDQGMKFGDGNCGYE

GMALFFSSH--LCSPLC
||. ||..|   |   |
GMFRFFYTHHVQCNHYC

Kinase AqueK040.AA Alpha_kinase 63-243 33 2e-74 258.33 Pfam 1-225 (225) Show / Hide
Range on Protein: 63-243
Range on HMM: 1-225/225
Sequence Identity: 33% (77 aa)

FAFGAMRECYRMKKLSKFSVQPDWHNASNYVAKCYKS----------EESATALKQDVQLQMDAKLWGEKYNKR-----NPPKKVDFFQAY-LITLKEPL
||.||||.|.||....    .|.| | .|.||| ||           ...    .||.. || .. | ||.|..     |||....| ... ...|. . 
FAQGAMRWCFRMFDTW----DPNWRNNQNCVAKWYKKIKNYNQKQSIYVEEDYYFQDCKMQMICQQWMEKFNQKLQEHNNPPPPIEFYDCCIVYELEDHN

N--------------GKTNYCVEHFMEG-NYIKYNSNSGYI-SDVNRLTP-----QAFSHFTFEKSGHQLIVVDIQGVG--D---LYTDPQIHTLDMKDY
.              |.. ...|...|| ...|||.|.|.. .  .| .|     |||||||...|..|..|.||||||  .   ..||||||| | . |
KPDCYQGFFSYRTDWGGKYWYMEPYIEGCEFVKYNNNYGWVYDNMDRNDPWNQYMQAFSHFTYHRSNGQMMVCDIQGVGYNNKCYYLTDPQIHTKD-GNY

------GEANLGDKGMALFFS-SHLCSPLC
      | .||| .|.  ||. .| |.. |
EMDFDEGMGNLGQEGIEKFFQNQHKCNHIC

Kinase AqueK040.AA VWL 152-248 44 3.5e-38 111.47 In-house 105-206 (206) Show / Hide
Range on Protein: 152-248
Range on HMM: 105-206/206
Sequence Identity: 44% (46 aa)

YCVEHFMEGNYIKYNSNSGYISD----VNRLTPQAFSHFTFEKSGHQLIVVDIQGVG-DLYTDPQIHTLDM-KDYGEANLGDKGMALFFSSHLCSPLCSA
| || ..|| | ||| |.|....     | |. |||||||.  |  .. .||.||..  . ||||||.||  . .|. |||  ||  ||..| |   |  
YFVENYIEGDYQKYNNNAGWCNQTDMEYNQLS-QAFSHFTWQYSQGYCMIVDLQGNEDGMLTDPQIHCLDQSHKFGQGNLGYEGMLRFFMTHQCNKYCQK

LGL
| |
LQL

Kinase AqueK040.AA Alpha-Unclassified 154-243 28 4.3e-25 78.66 In-house 110-215 (215) Show / Hide
Range on Protein: 154-243
Range on HMM: 110-215/215
Sequence Identity: 28% (30 aa)

VEHFMEGNYIKYNSNSG------YISDVNRLTPQAFSHFTFEKSGHQLIVVDIQG-VG------DLYTDPQIHTLDMKDYG--EANLGDKGMALFFSSH-
||  ..| . ||..|.|        ..      ....|.|.....|..||.| || |.         |||||||.. . |.    | | ...  .|..| 
VEPYLIGEFVKYSNNTGKEINFVKWEYEAYQYCCTYQHWTYQWTNHCDIVCDLQGWVDENDKKTWKMTDPQIHTIRQR-YQGFKTNCGMRFIDYWFNNHH

-LCSPLC
  |   |
VQCNHYC

Kinase AqueK040.AA ChaK 152-243 37 6.2e-12 43.48 In-house 120-219 (219) Show / Hide
Range on Protein: 152-243
Range on HMM: 120-219/219
Sequence Identity: 37% (37 aa)

YCVEHFMEGNYIKYNSNSG-YISDVNRLTP--QAFSHFTFEKSGHQLIVVDIQGVGDLYTDPQIHTLDMKD-----YGEANLGDKGMALFFSSHLCSPLC
. .|..| | . ||| | |  |   | |     ||||.|.|     |.|.|.||||.  ||| .   . |      .| ||||.  .  |   | |   |
FTIEKCMTGEFRKYNNNNGDEIIPTNTLEEIMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKPEEKQSCDMVFGPANLGEDAIRNFRAKHHCNSCC





Sel1 AqueK040.AA Sel1 376-410 16 8.783019 2.42 Pfam 1-41 (43) Show / Hide
Range on Protein: 376-410
Range on HMM: 1-41/43
Sequence Identity: 16% (7 aa)

GQVHYEMA--IYHSKGRFT--SEP-D-LDA-SLFHLHKAADL
    |...   .. .|.|    .. | ..  .. ...|||..
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQ

Sel1 AqueK040.AA Sel1 459-489 20 0.005869 12.96 Pfam 1-38 (43) Show / Hide
Range on Protein: 459-489
Range on HMM: 1-38/43
Sequence Identity: 20% (8 aa)

RQAMIVVG--RILETGE-N--SER-D-WKE-AAHWYTLA
  |.  .|  .....|. .   .. |  .. |..||..|
P-AQYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKA

Sel1 AqueK040.AA Sel1 441-458 20 24.165397 0.96 Pfam 24-43 (43) Show / Hide
Range on Protein: 441-458
Range on HMM: 24-43/43
Sequence Identity: 20% (4 aa)

DN-EAM-GLKYLKSAAKTGL
|.  .  ...... ||. | 
DDDYEKEAFYWYQKAAEQGH

Sel1 AqueK040.AA Sel1 508-541 36 0.000297 17.26 Pfam 3-43 (43) Show / Hide
Range on Protein: 508-541
Range on HMM: 3-43/43
Sequence Identity: 36% (15 aa)

MAKLG--NMYNTGKFG--LST-D-YEK-AGQYFQEAADLAM
. .||   || .|.||      | ||| | ...| ||..  
QYNLGMYYMYYHGQFGGCVPQDDDYEKEAFYWYQKAAEQGH