Gene AqueK232 (A.queenslandica)

AqueK232

Species: A.queenslandica
Alias: AqueK232
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: MSN

Sequence

Name Sequence Type Origin Length Description Download
AqueK232.AA Protein None 784 None Fasta, JSON
AqueK232.kin_dom Protein Kinase Domain None 266 None Fasta, JSON

Protein domain

Protein domains of AqueK232.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase AqueK232.AA MSN 17-282 75 3e-185 616.92 In-house 1-265 (265) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-265/265
Sequence Identity: 75% (201 aa)

FELIEVVGNGTYGQVFKGRHVKTGQLAAIKIMEVTEDEEEEIRLEVDVLRKYSYHTNIATYYGAFVKKSEPGTEDQLWLVMEFCGAGSITDLVKSTKTRS
|||.|||||||||||.||||||||||||||.|.|.|||||||..|...|.|||.| |||||||||.||| || ..|||.|||||||||.|||||.|| .|
FELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVREDEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPGHDHQLWMVMEFCGAGSVTDLVKMTKGQS

LKEEWIAYVAREVLRGLSHLHKNKVIHRDIKGQNVLLTDNADIKLVDFGVSAQLDRTIGKRNTFIGTPYWMAPEVIACDQDPHATYDYRSDQWSLGITSI
|||.||||..||.||||.|||..|||||||||||||||.||..||||||||||||||.|.||||||||||||||||||| .|.|||||||| ||.||| |
LKEDWIAYICREILRGLAHLHQHKVIHRDIKGQNVLLTHNAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSVGITAI

EIAEGEPPLCSMHPMRALFLIPRNPPPRLKMPKKWSPKFTSFIDQCLTKDPTKRPTSDELLRHPFV
|.|||.|||| ||||||||||||||||.||  |||| ||..|...|| |.  .||.....|.|||.
EMAEGQPPLCDMHPMRALFLIPRNPPPKLK-SKKWSKKFHNFMEKCLIKNYHQRPYTEQMLKHPFI
Kinase AqueK232.AA STE20 17-282 51 6.30000000001e-162 544.24 In-house 1-288 (288) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-288/288
Sequence Identity: 51% (149 aa)

FELIEVVGNGTYGQVFKGRHVKTGQL----AAIKIMEVTE-----DEEEEIRLEVDVLRKYSYHTNIATYYGAFVKKSEPGTEDQLWLVMEFCGAGSITD
.||.|..|.|.||.|.|..|..||..    .|||.|.. .     ||.|.|  |.......  | || .|||...|....  .|.||.|||.||.||.||
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCK-HPNIVKYYGSYLKDDTC--DDELWIVMEYCGGGSLTD

LVKST-KTR------SLKEEWIAYVAREVLRGLSHLHKNKVIHRDIKGQNVLLTDNADIKLVDFGVSAQLDR----TIG-KRNTFIGTPYWMAPEVIACD
..| . |.       ...||.|||. ||||.||..||.|..||||||..|.|||.....||.||||.|||..    |.. |||||.|||||||||||.|.
IMKHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCM

QDPHATYDYRSDQWSLGITSIEIAEGEPPLCSMHPMRALFLIP--RNPPPRLKM--PKKWSPKFTSFIDQCLTKDPTKRPTSDELLRHPFV
..|   |||..| |||||| || ||||||.. ||||||.|.||  .||||.||   |.||||.|  |.|.||.||| ||||...||.|||.
EGPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase AqueK232.AA STE 17-282 35 6.5e-133 447.87 In-house 1-359 (359) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-359/359
Sequence Identity: 35% (129 aa)

FELIEVVGNGTYGQVFKGRHVK---------------TGQLAAIKIMEVTE------------------DEEEEIRLEVDVLRKYSY-HTNIATYYGAFV
.|.||..|.|..|.|.|....|               ||.. |||.|.. .                  .|...|  |.....|..  | || .|||...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

KKSEP-GTEDQLWLVMEFCGAGSITDLVKST-KT-RSLK----------EEWIAYVAREVLRG-LSHLHKNKVIHRDIKGQNVLLTDNADIKLVDFGVSA
|.... . .|.||..||....||..|..|.. .. ..|.          |..|||..|..|.| |..||....||||||..|.||     .||.||||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

QLDR---------------TIG-KRNTFIGTPYWMAPEVIACDQDP-HATYDYRSDQWSLGITSIEIAEGEPPLCSMHPMRALFLIPRN-----------
||.                |.. |||||.||| ||||||| ... .    ||...| ||||.| || |.|.||.. ||||||.|.||.|           
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----PPPRLKM-----------------PKKWSPKFTSFIDQCLTKDPTKRPTSDELLR--HPFV
    |||.|.                  |.||||.|  ||..||.||| ||||...||.  |||.
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase AqueK232.AA NinaC 17-282 52 9.5e-133 447.32 In-house 1-267 (267) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-267/267
Sequence Identity: 52% (142 aa)

FELIEVVGNGTYGQVFKGRHVKTGQLAAIKIMEVTEDEEEEIRLEVDVLRKYSYHTNIATYYGAFVKKSEPGTEDQLWLVMEFCGAGSITDLVKS--TKT
.| .| .| |||| |||    . ||.||.||..  .| .|||  |  .||.|. | |.  .|| . .|...   ||||.|||.|  ||.||.||      
WEIYETIGKGTYGKVFKVKNKDNGQIAAVKIQHYIHDHDEEIEAEYNILRDYCDHPNVVRFYGMY-YKKDKCNGDQLWFVMEYCNGGSVTDMVKGLLKCG

RSLKEEWIAYVAREVLRGLSHLHKNKVIHRDIKGQNVLLTDNADIKLVDFGVSAQLDRTIGKRNTFIGTPYWMAPEVIACDQDPHATYDYRSDQWSLGIT
| ..|| |||. .| ..|| |||.|.|||||.|| |.||| .  .||.||||||||| | ..||| .|||.||||||||| |    .|| | | ||||||
RRMREEHIAYILHEACMGLQHLHCNHVIHRDVKGNNILLTTEGGVKLCDFGVSAQLDSTRHRRNTCVGTPCWMAPEVIACMQQYDPDYDARCDVWSLGIT

SIEIAEGEPPLCSMHPMRALFLIPRNPPPRLKMPKKWSPKFTSFIDQCLTKDPTKRPTSDELLRHPFV
 || . |.||.  ||||||.| |||||||.|  | .|. .|  || |||.||  |||.  ..| |||.
AIELGDGDPPFADMHPMRAMFKIPRNPPPTLMHPENWCQEFNDFISQCLEKDYEKRPMMVHMLEHPFI
Kinase AqueK232.AA YSK 17-282 46 6.4e-121 365.91 In-house 1-257 (257) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-257/257
Sequence Identity: 46% (125 aa)

FELIEVVGNGTYGQVFKGRHVKTGQLAAIKI--MEVTEDEEEEIRLEVDVLRKYSYHTNIATYYGAFVKKSEPGTEDQLWLVMEFCGAGSITDLVKSTKT
|   |..| | .| |.||  ..|..  ||||   |  ||| | |  |. .|       .|  |||.. | .       || .||.|| ||. || |.   
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSP-YITKYYGSYLKDT------KLWIIMEYCGGGSCLDLMKPKYV

RSLKEEWIAYVAREVLRGLSHLHKNKVIHRDIKGQNVLLTDNADIKLVDFGVSAQLDRTIGKRNTFIGTPYWMAPEVIAC--DQDPHATYDYRSDQWSLG
 .. |. || . ||.| ||. ||....||||||  ||||. . |.|| ||||..|.  |  |||||.||||||||||| .  ..     ||.  | ||||
GQFDEKYIAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSY-----YDFKADIWSLG

ITSIEIAEGEPPLCSMHPMRALFLIPRNPPPRLKMPK-KWSPKFTSFIDQCLTKDPTKRPTSDELLRHPFV
|| .|.| ||||.| .||||..|||| |.||.|.  . ..|  |  |.. || ||| .||. .||| | |.
ITAYEMAKGEPPYCDYHPMRVMFLIPKNNPPKLE--GRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase AqueK232.AA MST 17-282 46 5.3e-115 367.0 In-house 1-254 (254) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-254/254
Sequence Identity: 46% (126 aa)

FELIEVVGNGTYGQVFKGRHVKTGQLAAIKIMEVTEDEE-EEIRLEVDVLRKYSYHTNIATYYGAFV--KKSEPGTEDQLWLVMEFCGAGSITDLVKSTK
|...|  | | ||.|.|  | .||.. |||.. |  .|  .||  |   . .    ..| .||| .   |      . ..|.|||.||.||. |..| |.
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPV--NEDLQEIIKEISIM-QQCKSKYIVKYYGSYFDAK------NNHCWIVMEYCGMGSVCDIMKITQ

TRSLKEEWIAYVAREVLRGLSHLHKNKVIHRDIKGQNVLLTDNADIKLVDFGVSAQLDRTIGKRNTFIGTPYWMAPEVIACDQDPHATYDYRSDQWSLGI
 | | |. || . . .|.||  ||.|| ||||||  | ||      || |||||.||  | .||||.||||||||||||      .  ||.  | |||||
-RTLNEQQIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQ-----EIKYDCKADIWSLGI

TSIEIAEGEPPLCSMHPMRALFLIPRNPPPRLKMPKKWSPKFTSFIDQCLTKDPTKRPTSDELLRHPFV
| || |||.||.   |||||.|.|| .||| .| | .||. |. |. .||.|.| .|.|. .|| |||.
TAIEMAEGMPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase AqueK232.AA KHS 17-282 47 2.3e-104 351.99 In-house 1-258 (258) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-258/258
Sequence Identity: 47% (127 aa)

FELIEVVGNGTYGQVFKGRHVKTGQLAAIKIMEVTEDEE-EEIRLEVDVLRKYSYHTNIATYYGAFVKKSEPGTEDQLWLVMEFCGAGSITDLVKSTKTR
.||.  || ||||.|.| |......|||.|.. .  ... . |  |. .... . |.||  |.|.....      |.||..||.||.||. |. .   | 
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKMEPGDDFAVIQQEIMMMKDCR-HPNIVAYFGSYLRR------DKLWICMEYCGGGSLQDIYHV--TG

SLKEEWIAYVAREVLRGLSHLHKNKVIHRDIKGQNVLLTDNADIKLVDFGVSAQLDRTIGKRNTFIGTPYWMAPEVIACDQDPHATYDYRSDQWSLGITS
.|.|  ||||.||.|.|| .|| .. .|||||| |.||||. |.|| |||||||.  ||.||  |||||||||||| | ..  .  |.   | |..||| 
PLSELQIAYVCRETLQGLHYLHSMGKMHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVER--KGGYNQLCDIWAVGITA

IEIAEGEPPLCSMHPMRALFLIPRNP--PPRLKMPKKWSPKFTSFIDQCLTKDPTKRPTSDELLRHPFV
||.||  ||.  .||||||||. .    ||.||  .|||..|  |. ..|||.| ||||.. ||.||||
IELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase AqueK232.AA PAKL 17-282 42 1.5e-100 340.38 In-house 1-256 (256) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-256/256
Sequence Identity: 42% (113 aa)

FELIEVVGNGTYGQVFKGRHVKTGQLAAIKIMEVTED-EEEEIRLEVDVLRKYSYHTNIATYYGAFVKKSEPGTE-DQLWLVMEFCGAGSITDLVKSTKT
||. |  | | || |.|. |  |.   ||| .|..|  | ..|  |...| |     ||  |.|         .. ...|  |..| .||| |. .|.  
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIEIKESNEIKDIEKEIQILKK-CKCPNIVSYFGSIQ------QKLNHYWILMDYCSLGSINDMMESC-C

RSLKEEWIAYVAREVLRGLSHLHKNKVIHRDIKGQNVLLTDNADIKLVDFGVSAQLDRTIG-KRNTFIGTPYWMAPEVIACDQDPHATYDYRSDQWSLGI
 .|.|. |. . . .|.||  ||   .||||||  |.||.  ...|. ||||| ||. . .   |  ||||||||||.|       . |..  | |||||
KTLNEKQISVILQQTLKGLHYLHSKNIIHRDIKAANILLNEDCQVKIADFGVSQQLQDEYDGQANQMIGTPYWMAPEIIN-----KQNYNNKCDIWSLGI

TSIEIAEGEPPLCSMHPMRALFLIPRNPPPRLKMPKKWSPKFTSFIDQCLTKDPTKRPTSDELLRHPFV
| || |.|.||.  | ||||.  ||. ||| .. ||.||| | .|..||..||| ||.   .|| ||| 
TAIEMADGFPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase AqueK232.AA PAKA 17-282 41 8.7e-95 321.21 In-house 1-260 (260) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-260/260
Sequence Identity: 41% (112 aa)

FELIEVVGNGTYGQVFKGRHVKTGQL--AAIKIMEVTEDEEE-EIRLEVDVLRKYSYHTNIATYYGAFVKKSEPGTEDQLWLVMEFCGAGSITDLVKSTK
.. .| .| |  |.|...  .||.|    ||| |.. ..     |  |  |. | . | ||  |. ...       .|.||.|||. ..|. ||... . 
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKKELIINEILVM-KECKHKNIVNYIDSYLV------DDELWVVMEYMEGGCLTDVITQCC

---TRSLKEEWIAYVAREVLRGLSHLHKNKVIHRDIKGQNVLLTDNADIKLVDFGVSAQLDRTIGKRNTFIGTPYWMAPEVIACDQDPHATYDYRSDQWS
   .  ..|. |||| ||.|.||. .|....||||||  |.||  ....|. |||  ||| .   ||||  |||||||||||   |     ||.  | ||
NIQCNYMDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQ-----YDEKVDIWS

LGITSIEIAEGEPPLCSMHPMRALFLIPRNPPPRLKMPKKWSPKFTSFIDQCLTKDPTKRPTSDELLRHPFV
|||  ||..|||||  .. | ||..||  |  | .| | |||..|  | |.|| .|. .|....|||.||| 
LGIMAIEMIEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase AqueK232.AA S_TKc 17-282 32 3.5e-94 320.12 SMART 1-231 (231) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-231/231
Sequence Identity: 32% (90 aa)

FELIEVVGNGTYGQVFKGRHVKTGQLAAIKIMEVTEDEEEEIRLEVDVLRKYSYHTNIATYYGAFVKKSEPGTEDQLWLVMEFCGA--GSITDLVKSTKT
.|.....| |..|.|.|.||.|||.. ||||.       | || |...|.|   | || ..|..|.        | |..|||.|.   |.  |. |. ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD-------DHLYMVMEYCDGDLGDLFDYIKKRGR

----RSLKEEWIAYVAREVLRGLSHLHKNKVIHRDIKGQNVLLTDNADIKLVDFGVSAQLDRTIGKRNTFIGTPYWMAPEVIACDQDPHATYDY-RSDQW
    . . | ............| ..|....||||.| .|.||..   ||. |||...||       .||.|||..|||||.         |.. ..| |
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL--------GYGKCKCDWW

SLGITSIEIAEGEPPLCSMHPMRALFLIPRNPPPRLKMPKKWSPKFTSFIDQCLTKDPTKRPTSDELLR-------HPFV
|.|.. .| . |.|| .  .... . .|              || . .||..||.|||.||||  |.|.       ||..
SCGCILYEMLCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK232.AA SLK 17-282 42 3e-92 311.54 In-house 1-259 (259) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-259/259
Sequence Identity: 42% (114 aa)

FELIEVVGNGTYGQVFKGRHVKTGQLAAIKIMEVTEDEE-EEIRLEVDVLRKYSYHTNIATYYGAFVKKSEPGTEDQLWLVMEFCGAGSITDLVKSTKTR
.|.|  .|.| .|.| | .|  ....|| |..|. ..|| |.   |.|.| .   | ||   |.|.        ...||...|||. | . | .     .
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMIEIKDEEELEDYMVEIDILSECK-HPNIVKLYEAYY------YDNKLWMMIEFCDGGAV-DNIMVELEH

SLKEEWIAYVAREVLRGLSHLHKNKVIHRDIKGQNVLLTDNADIKLVDFGVSAQLDRTIGKRNTFIGTPYWMAPEVIACDQDPHATYDYRSDQWSLGITS
.|.|. |.||..... .| .||.|||||||.|  |.|.| . |..| ||||||.. .|. || |||||||||||||..|.    . |||..| |||||| 
PLTEDQIQYVCKHMCEALNWLHSNKVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITL

IEIAEGEPPLCSMHPMRALFLIPRNPPPRLKMPKKWSPKFTSFIDQCLTKDPTKRPTSDELLRHPFV
||.|..|||   | ||| |. | .  ||.|. | .|| .|  |. .|| ||| .|.|...|..|..|
IEMAQMEPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase AqueK232.AA Pkinase 17-282 27 1e-81 282.61 Pfam 1-293 (293) Show / Hide 
Range on Protein: 17-282
Range on HMM: 1-293/293
Sequence Identity: 27% (84 aa)

FELIEVVGNGTYGQVFKGRHVKTGQLAAIKIMEVTEDEEEE---IRL--EVDVLRKYSYHTNIATYYGAFVKKSEPGTEDQLWLVMEFCGAG----SITD
.......| |..|.|.|..|..||.. |.||... ......    |.  |. .... . | || ..|..|        .| ...|||.|. |    .  |
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPNIVRLYDWFED------KDHIYMVMEYCEGGLYVMDLFD

LVKSTKTRSL--KEEWIAYVAREVLRGLSHLHKNKVIHRDIKGQNVLLTDNADI----KLVDFGVSAQL-DRTIGKRNTFIGTPYWMAPEVIACDQDPHA
...  . ...   |. .  .....|||| ..|....||||.| .|.|. .| .|    |. |||...|.     .  .|| |||..||||||      . 
YISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR----GGQ

TYDYRSDQWSLGITSIEIAEGEPPLCSM----HPMRALFLIPRNPPPRLKMPKKWS---------------------PKFTSFIDQCLTKDPTKRPTSDE
 |....| ||.|.. .| . |.|| ..     . .. ...| |. .|.|. .  |.                     . . .||. ||.|||.|||| ..
YYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQ

LLRHPFV
.| ||..
ILQHPWF
Kinase AqueK232.AA Pkinase_Tyr 17-167 24 1e-26 91.11 Pfam 1-158 (270) Show / Hide 
Range on Protein: 17-167
Range on HMM: 1-158/270
Sequence Identity: 24% (39 aa)

FELIEVVGNGTYGQVFKGRHV----KTGQLAAIKIM--EVTEDE--EEEIRLEVDVLRKYSYHTNIATYYGAFVKKSEPGTEDQLWLVMEFCGAGSITDL
 ..... | | .|.|.||.      .|..  |.|..    ....   |.   |. ..... .| ||  .||. ....||.   |...|||..  |.  | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN---QIYIVMEYMPHGDLLDY

VKST--KTRSLKEEWIAYVAREVLRGLSHLHKNKVIHRDIKGQNVLLTDNADIKLVDFGVS
 ..     ..|. ...   .... .|...|. .. ||||.   |.|.|.|  .|  ||| .
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase AqueK232.AA TyrKc 17-285 22 3e-16 40.09 SMART 1-280 (280) Show / Hide 
Range on Protein: 17-285
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

FELIEVVGNGTYGQVFKGRHVKTGQLAAIKIMEVTEDEEEEIRLEVDVLRKY-SYHTNIATYYGAFVKKSEPGTE---DQLWLVMEFCGAGSITDLVKST
 .|... |.| .|.|.||.     .  |.| .      .|... |  ...|.   | ||   ||. .....       ..|..|||..  |.  |  ...
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRN--FMYIEPLMIVMEYMPHGDLKDYLRKH

KTRSLKEEWIAYVAREVLRGLSHLHKNKVIHRDIKGQNVLLTDNADIKLVDFGVSAQLDRT--------IGKRNTFIGTP-----YWMAPEVIACDQDPH
. . |. .   . .  . .| ..||....||||.   |.|...|  .|  ||| |  ..            .  .  |.       |||||.|      .
RPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-----NY

ATYDYRSDQWSLGITSIEIAE-GEPPLCS-----MHPMRALFLIPRNPPPRLKMPKK--------WSPKFTSFIDQCLTKDPTKRPTSDELLRHPFVNDF
 ..   || || |..  ||   |..|        | . ... .. .    |.. |.          ...  . . ||   || .|||  |.     . .|
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQG--YRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-----HECF
Kinase AqueK232.AA Pkinase_Tyr 186-272 28 7e-06 20.48 Pfam 180-262 (270) Show / Hide 
Range on Protein: 186-272
Range on HMM: 180-262/270
Sequence Identity: 28% (26 aa)

WMAPEVIACDQDPHATYDYRSDQWSLGITSIEIAE-GEPP-LCSMHPMRALFLI-PRNPPPRLKMPKKWSPKFTSFIDQCLTKDPTKRPT
|||||.|.        .   || || |..  ||   || |    | . . . .|  ..    ...|.. ...  . . ||  .|| .|||
WMAPECINYGK-----FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYR--MPCPENCPDEIYDLMKQCWHYDPEDRPT
CNH AqueK232.AA CNH 461-760 21 4.9e-77 263.17 SMART 1-375 (375) Show / Hide 
Range on Protein: 461-760
Range on HMM: 1-375/375
Sequence Identity: 21% (81 aa)

YKRKFTSEILCGALWGVNLLVGTDNGLMLLDRSGH------GKVFPLISRRKFSQIDVLEGLNVLIGINGRKNKLRIYYLSWLKQK--------I---MK
.. |....|.| .|||..|||||. |...|....       |.. ....|| .....|.|..|.|. | |.| .|. ..|.||.||        .    .
CTMKWCHPITCDQLWGKWLLVGTEHGIYCLNINCQQNQDHEGTPEHIHHRRCVTCMWVYEENNCLMMISGKKPHLYSHPLVWLFQKYRTQGMTPHIQDHM

HELDSPHTRQGF-VPVGDLEH-CVHYKV-ARSDK--MKYLVIGTKTGVEVYAWAQRPYSKFMAFKS----------------FPDLPNKPILVDMVHMPG
.  ...  ...  . ..|..  |.|..| ..      ..|.  ... |..|... .|. ||| .||                || . . | .|. .|   
CNHHLVPRKNVWTTKIPDTKGNCHHCCVKCNGKRTGIIFLCHAMQHSVQIYNQWYNPMHKFMCWKSSNNILNNEIEMFKHFRFPEIFPVPVFVCFHHDSF

GKSKVVYASTS------GFHAVDMD-------------TGVVQNIYIPAAAARGP--IL---PHAIIPLPSKP----SELLLCHNNEGVYVDSEG---RS
 ..........      |||.|. .             |  . ..... .   .   ..   ||......  .    ...||| .|.||.|...|   | 
ERPWICIGCDKPVGGMYGFHMVQHHQHCHCNSFNMHESTVNMNDHSLWFMNQQTSHQQDTCKPHQVHQVQQSDGGQRDMYLLCYDNFGVFVNCYGSEWRR

TKDTRLQWGEEPSSVALIGESHVMGWGSKAIEIRAVESGQL-DGVFMHK---RTQKLRFLCE---RNDKVFFASIR
...  |.|...| ..| ..  ..|......|.||....|.. ....|..   ...|.|.||.   |..|.|..|..
WRNPILHWEFMPEYFAYHY-PYIMAFWDNGIQIRHIKTGEWNTQCIMDRQYIKCRKFRLLCTCECRDRKIFYCSQP
CNH AqueK232.AA CNH 470-751 23 2.3e-64 224.94 Pfam 1-336 (336) Show / Hide 
Range on Protein: 470-751
Range on HMM: 1-336/336
Sequence Identity: 23% (80 aa)

LCGALWGVNLLVG-TDNGLMLLDR------SGHGKVFPLISRRKFSQIDVLEGLNVLIGI--NGRKNKLRIYYLSWLKQKI-----MKHELDSPHTRQ--
.| . ||..|||| || ||.....      .. ...  ..|| ...||.|.| .|.|| |   .. ..|. ..|.||.||.     . .   ..  |.  
VCPCTWGQWLLVGTTDEGLYVYNIRNTRDCRHWTRICQKFSR-RVTQIYVIEEFNILIMISGCDKNKHLYVHPLDWLDQKEQQWHQCHNPKHRCTHRIER

-------GFVPVGDLEHCVHYK--VARSDKMKYLVIGTKT-----GVEVYAWAQRPYSKF----------MAFKSFPD-LPNK----PILVDMVHMPGGK
       . ....|. || ...  ...  . ..|..  |.     .. .| |.. | .||          ..|. |.. .       .  ..|  .|  |
IMPRKFAMWQKLPDTKHCHFFCWIRNGYCNGRCLCCAVKRSGLHSTIKCYEWYH-PMKKFHKQRSFKGNQEWFRKFRECFYIPLPPMTECFSMHWLPQEK

SKVVYASTSGFHAVDMD-TGVVQNIYIPAAAA--------RGPILPHAIIPLPSKPS-ELLLCHNNEGVYVDSEGR-STK--DTRLQWGEEPSSVALIGE
.|. .....|||.|..| ||. . ...||           |  . |........  . |.||| ....|||...|.  ..  | ...| ..| |.|.  .
PKLCVGCQKGFHIVNLDGTGQPWWLHDPADHSVQQDFMARRENCKPICMHRIND--DEEFLLCYDECCVYVNKQGWPRSRKHDWEIMWEGMPQSFAC-CY

SHVMGWGSKAIEIRAVESG-QLDGVFMHKRTQKLRFLCERN
 ..... ...|||| ||.| ..|..... . |..|||....
PYLLAFHPNFIEIRHVETGSEWDACVQCIPGQNIRFLHSGS