Gene AqueK517 (A.queenslandica)
AqueK517
Species: A.queenslandica
Alias: AqueK517
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| AqueK517.AA | Protein | None | 154 | None | Fasta, JSON |
| AqueK517.kin_dom | Protein Kinase Domain | None | 111 | None | Fasta, JSON |
Protein domains of AqueK517.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | AqueK517.AA | TKL | 1-154 | 20 | 6.6e-23 | 79.33 | In-house | 138-362 (364) | Show / Hide |
Range on Protein: 1-154 Range on HMM: 138-362/364 Sequence Identity: 20% (45 aa) MHDVAVGLNYLHTLPI-----DNIVHHDVSSANVLLESKGP----------EKWKTKISDFGSANIVRR----------------------AVSRAPGAE ..|.| |.||||. .|.| | |.|.|. ... . |. ||.||| . . . . .. | ALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTP VYSAPECFQGVSNQYSAV----------QTPKMDVYSYGILFCEALTCKFPDR-SSFQDML------QQVWSSTKSVGLITRS------------LHH-- . |||...| | ..| ..|.||||.||...| ||.. | . . .|. . . . .. . RWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPP ---ELIKSCTKDNPYKRPTMNEVIS .|.. | . .| |||...|... SMKKLMQDCWDHDPEKRPSFQEILK |
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| Kinase | AqueK517.AA | CZAK | 3-104 | 32 | 1.7e-13 | 45.5 | In-house | 113-221 (279) | Show / Hide |
Range on Protein: 3-104 Range on HMM: 113-221/279 Sequence Identity: 32% (37 aa) DVAVGLNYLHT-LPIDNIVHHDVSSANVLLESKGP---------EKWKTKISDFGSANIVRRAVS---RAPGAEVYSAPECFQGVSNQYSAVQTPKMDVY |.| | ||||. |.| | || |.||.. . ||.||| . . . | . ||||| | .. |.| ||| DIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTMGCLCWMAPECFKGENY------TEKVDVY SYGILFCEALTCKFP |.|.. . .|| | SFGMILWCIITCDQP |
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| Kinase | AqueK517.AA | TK | 1-154 | 17 | 6e-11 | 32.15 | In-house | 240-484 (486) | Show / Hide |
Range on Protein: 1-154
Range on HMM: 240-484/486
Sequence Identity: 17% (44 aa)
MHDVAVGLNYLHTLPI---DNIVHHDVSSANVLLESKGPEKWK-------TKISDFGSA---------------NIVRRA-VSRAPGAEV----------
....| |. ||| ... |.|| |. |.|. .... ||. ||.||| . . .|. ... ..
CWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPM-WPFEDDPWQDY
------------YSAPECFQ-GVSNQY--SAVQTPKMDVYSYGILFCEALT---CKFPDRSSFQD-----MLQQVWSSTKSV-------------GLITR
. ||||.. .| . . |.| ||.|.|.| | .| .. | || .|.| .. ..
YRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMP
--------------------SLHHELIKSCTKDNPYKRPTMNEVIS
....|...| . .| .|||. .. .
QPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHE
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| Kinase | AqueK517.AA | TKL-Unique | 2-104 | 29 | 2.4e-10 | 32.87 | In-house | 117-233 (290) | Show / Hide |
Range on Protein: 2-104 Range on HMM: 117-233/290 Sequence Identity: 29% (36 aa) HDVAVGLNYLHTLPIDNIVHHDVSSANVLLESK-GPEKWKTKISDFG----SANIVRRAVSRA-----PGAE---VYSAPECFQGVSNQYSAVQTPKMDV .|.| |..|||.. | | | | |.|. .. .|. ||.||| ...| . ... .. . ..||| . .. .||| | || IDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSE----KSDV YSYGILFCEALTCKF------P ||.|| | .| | | YSFGIVLWEIATRKITKTYKKP |
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| Kinase | AqueK517.AA | MLK | 1-104 | 29 | 9.9e-10 | 30.06 | In-house | 130-235 (291) | Show / Hide |
Range on Protein: 1-104 Range on HMM: 130-235/291 Sequence Identity: 29% (32 aa) MHDVAVGLNYLHTLPIDNIVHHDVSSANVLLES--KGPEKWKTKISDFGSANIVRRA---VSRAPGAEVYSAPECFQG-VSNQYSAVQTPKMDVYSYGIL ....| |..||| . . |.|.| | |.|. . .. . ||.||| . . . ..| . ||| .| ...|| | ||.|.|.. ALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAWMAPEVIQQFRCEKYSE----KCDVWSWGVV FCEALTCKFP . | ||.. | LWEMLTREVP |
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| Kinase | AqueK517.AA | TK-Unique | 3-94 | 29 | 1.6e-09 | 29.14 | In-house | 139-228 (294) | Show / Hide |
Range on Protein: 3-94 Range on HMM: 139-228/294 Sequence Identity: 29% (29 aa) DVAVGLNYLHTLPIDNIVHHDVSSANVLLESKGPEKWKTKISDFGSA------NIVRRAVSRAPGAEVYSAPECFQGVSNQYSAVQ-TPKMDVYSYGIL ..| |..||. .. ..|||.|... |||| . . . ||.||| | . . . |. . . ||| .. . |.| ||.|.|.| QIACGMEYLASQR-KKIVHRDLCARNVLLTE----DKVCKICDFGMARDVYTNGVYSMMCSQGRIPIRWMAPESLKCY----HGMYHTTKSDVWSFGVL |
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| Kinase | AqueK517.AA | Dicty5 | 3-104 | 35 | 1.8e-09 | 28.79 | In-house | 112-202 (260) | Show / Hide |
Range on Protein: 3-104 Range on HMM: 112-202/260 Sequence Identity: 35% (37 aa) DVAVGLNYLHTLPIDNIVHHDVSSANVLLESKGPEKWKTKISDFGSANIVRRAVSRAP--GAEVYSAPECFQGVSNQYSAVQTPKMDVYSYGILFCEALT |.| .. .|| ||.| |. | |.|. | || || ||| | . | . |.| |.| . | . | ||||.|| | .| DIAQSMRHLHSM---NIIHRDLKSMNFLIT----ENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNG--QPY----HQKCDVYSFGIVLWEMFT CKFP | | RKEP |
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| Kinase | AqueK517.AA | C8 | 7-95 | 29 | 2.4e-09 | 28.69 | In-house | 135-226 (226) | Show / Hide |
Range on Protein: 7-95 Range on HMM: 135-226/226 Sequence Identity: 29% (28 aa) GLNYLHTLPIDNIVHHDVSSANVLLESKGPEKWKTKISDFGSANIVRRAVS----RAP---GAEVYSAPECFQGVSNQYSAVQTPKMDVYSYGILF |.||.| . ||.| |. | |. .. . . |..||| | |. | . | |.||| .. ||| . . |..| |.. GVNYIH---CKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRI-QSDLFSVGLVL |
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| Kinase | AqueK517.AA | Dicty4-Unclassified | 3-100 | 31 | 1.3e-07 | 22.11 | In-house | 117-203 (263) | Show / Hide |
Range on Protein: 3-100 Range on HMM: 117-203/263 Sequence Identity: 31% (31 aa) DVAVGLNYLHTLPIDNIVHHDVSSANVLLESKGPEKWKTKISDFGSANIVRRAVSRAPGA--EVYSAPECFQGVSNQYSAVQTPKMDVYSYGILFCEALT |.| |. .||| |..| |. |.|.|. || ||| . . | .||| . | | . | |||||... | .| DIAQGMQHLHTR---NFIHRDIKSSNILMD----KHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHES--Y----NQKSDVYSYAMMLYELAT |
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| Kinase | AqueK517.AA | LRRK | 3-94 | 28 | 5e-07 | 20.89 | In-house | 172-271 (351) | Show / Hide |
Range on Protein: 3-94 Range on HMM: 172-271/351 Sequence Identity: 28% (30 aa) DVAVGLNYLHTLPIDN--IVHHDVSSANVLL-ESKGP-------EKWKTKISDFGSAN---IVRRA-VSRAPGAEVYSAPECFQGV-SNQYSAVQTPKMD ..| |..||| | |.| | | |.|| .|. . . . ||.||| ... . ... | ... |||. .. .| | | | QIAKGMEYLHS---HNPPIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEY----TEKVD VYSYGIL .||.|.. CYSFGMI |
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| Kinase | AqueK517.AA | S_TKc | 1-154 | 15 | 6.8e-05 | -105.12 | SMART | 18-220 (231) | Show / Hide |
Range on Protein: 1-154
Range on HMM: 18-220/231
Sequence Identity: 15% (36 aa)
MHDVA-----------------------------------------------VG-----LNYLHTLPI---------------------------DNIVH
... | . |.. . .|.|
CRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYMYQICCALEYCHSHGIIH
HDVSSANVLLESKGPEKWKTKISDFGSANIVRRAVSRAPGAEVYSAPECFQGVSNQYSAVQTPKMDVYSYGILFCEALTCKFPDRSSFQDMLQQVWSSTK
|. .|.|| . ||.|||.| .. . | | ||| . ..| |..| |... | |. . | . | |....
RDLKPENILLDE------HIKICDFGLARQL----TTFCGTPWYMAPEVL--------GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG----
SVGLITRSLHHELIKSCTKDNPYKRPTMNEVIS
.... . .|. | . .| |||| |.
-----SPEAKD-FIRKCLQKDPEKRPTA-EALQ
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| Kinase | AqueK517.AA | Dicty4-Unclassified | 134-153 | 60 | 0.000183 | 11.16 | In-house | 241-260 (263) | Show / Hide |
Range on Protein: 134-153 Range on HMM: 241-260/263 Sequence Identity: 60% (12 aa) LIKSCTKDNPYKRPTMNEVI ||| | . | ||||||..| LIKWCWHNDPNKRPTMNQII |
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| Kinase | AqueK517.AA | Pkinase | 7-104 | 28 | 0.000211 | 16.65 | Pfam | 120-211 (293) | Show / Hide |
Range on Protein: 7-104 Range on HMM: 120-211/293 Sequence Identity: 28% (29 aa) GLNYLHTLPIDNIVHHDVSSANVLLESKGPEKWKTKISDFGSA----NIVRRAVSRAPGAEVYSAPECFQGVSNQYSAVQTPKMDVYSYGILFCEALTCK ||.|.| .|.| |. ..|.|. ..| . . ||.|||.| . . . | | ||| . . .|| |..|.|... | |. . GLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-----GGQYYGPKVDMWSCGCILYEMLCGR FP .| PP |
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| Kinase | AqueK517.AA | LRRK | 133-154 | 31 | 0.000373 | 10.58 | In-house | 326-347 (351) | Show / Hide |
Range on Protein: 133-154 Range on HMM: 326-347/351 Sequence Identity: 31% (7 aa) ELIKSCTKDNPYKRPTMNEVIS .||..| . .| |||....... DLIQHCWQHDPKKRPHFSQIVK |
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| Kinase | AqueK517.AA | TKL-Unique | 133-154 | 36 | 0.014704 | 5.06 | In-house | 267-288 (290) | Show / Hide |
Range on Protein: 133-154 Range on HMM: 267-288/290 Sequence Identity: 36% (8 aa) ELIKSCTKDNPYKRPTMNEVIS .||. | ...| .||. .|.|. DLIQQCWHHDPSQRPSFDEIIH |
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| Kinase | AqueK517.AA | TK-Unique | 132-154 | 30 | 0.033016 | 3.56 | In-house | 270-292 (294) | Show / Hide |
Range on Protein: 132-154 Range on HMM: 270-292/294 Sequence Identity: 30% (7 aa) HELIKSCTKDNPYKRPTMNEVIS ..|.|||....| .||. .... YNLMKSCWQWEPEERPSFRQIKH |
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| Kinase | AqueK517.AA | MLK | 133-154 | 31 | 0.073261 | 2.4 | In-house | 268-289 (291) | Show / Hide |
Range on Protein: 133-154 Range on HMM: 268-289/291 Sequence Identity: 31% (7 aa) ELIKSCTKDNPYKRPTMNEVIS .|.| | ...| |||.. .... KLMKQCWNQDPHKRPSFRQIVQ |
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| Kinase | AqueK517.AA | Dicty5 | 134-153 | 40 | 0.082795 | 2.0 | In-house | 234-253 (260) | Show / Hide |
Range on Protein: 134-153 Range on HMM: 234-253/260 Sequence Identity: 40% (8 aa) LIKSCTKDNPYKRPTMNEVI |||.| . | .||. |.. LIKKCWQQKPHNRPSFKEIC |
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