Gene AqueK657 (A.queenslandica)

AqueK657

Species: A.queenslandica
Alias: AqueK657
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: LZK

Sequence

Name Sequence Type Origin Length Description Download
AqueK657.AA Protein None 515 None Fasta, JSON
AqueK657.kin_dom Protein Kinase Domain None 295 None Fasta, JSON

Protein domain

Protein domains of AqueK657.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc AqueK657.AA S_TKc 15-341 16 6e-15 42.25 SMART 1-231 (231) Show / Hide 
Range on Protein: 15-341
Range on HMM: 1-231/231
Sequence Identity: 16% (57 aa)

FLISHLLSADQHGIVVASYCRVAGHPFPSKLYAVKLIFNFTDDDYSSSVLSNHFENEWLLLSSLPPHPQIIKYWCQFVSVIPMEFVECCPQEVCKSFPKD
. |  ..     | |   . .        ...|.| |              .|...|  .|..   || |.|.   |..                     
YEILRKIGKGAFGKVYKCRHKK-----TGRIVAIKIIK-------------EHIRREIQILKK--HHPNIVKLYDVFQD---------------------

KHFTRKGQFIVLDYHPQ---TLQEFLTKEEN----KPVDFKIILSISSQILSAASYLESNMICHLDLKLANCLVRGEEEDNPHIVLCDFGSAVQFSDSTM
     .  ..|..| ..   .| ... |       .| .   . ..  ||..|  |. |. |.| ||| .| |.        || .||||.| |.     
-----DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL-----

STQWCHGLSLGGNRAHLCPELLSQYYSYKTSTSRLQQPSAAPISLAQRLLCYKGQPSF------AVGVLLYEVGSCGEHPLPDYPLNYMKEGVVTYGESD
        .. | .  . ||.|                                . ..      ..|..|||  . |. | |   .. | . ..      
-------TTFCGTPWYMAPEVL--------------------------------GYGKCKCDWWSCGCILYEMLC-GYPPFP--QMQMMFKKIG------

IAELPGAYCHQQYFDLLKSLIACDPKQRPNLEHTLD-------TICK
          ..  |... .   ||..||     |            
---------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase AqueK657.AA CAMK-Unique 150-212 32 2.8e-12 36.61 In-house 159-236 (363) Show / Hide 
Range on Protein: 150-212
Range on HMM: 159-236/363
Sequence Identity: 32% (25 aa)

ILSISSQILSAASYLESNMICHLDLKLANCLVRGEEED------------NPHIVLCDFGSAVQFSDSTMST---QWC
...|. ..||| .|. |. | | |||| |..|. .. |            | ||.||||| ..... . |..     |
TCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHHRDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMC
Kinase AqueK657.AA DAPK 156-197 42 3.4e-12 29.57 In-house 111-152 (264) Show / Hide 
Range on Protein: 156-197
Range on HMM: 111-152/264
Sequence Identity: 42% (18 aa)

QILSAASYLESNMICHLDLKLANCLVRGEEEDNPHIVLCDFG
||| .  || |. |||||||  | .  ...  ...| ..|||
QILEGVHYLHSRNICHLDLKPQNIMLTDRNIPQGDIKIIDFG
Kinase AqueK657.AA Pkinase 124-215 22 4.4e-12 43.81 Pfam 77-171 (293) Show / Hide 
Range on Protein: 124-215
Range on HMM: 77-171/293
Sequence Identity: 22% (22 aa)

IVLDYHPQ-----TLQEFLTKEENKPV--DFKIILSISSQILSAASYLESNMICHLDLKLANCLVRGEEEDNPHIVLCDFGSAVQFSDSTMSTQWCHGL
.|..|..       | .... ......  . . . ..  |||..  |. |. |.| |||..|.|.  . . .... .||||.| ||.  . . . ....
MVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTF
Kinase AqueK657.AA CAMK 156-212 22 2.8e-11 31.87 In-house 187-280 (425) Show / Hide 
Range on Protein: 156-212
Range on HMM: 187-280/425
Sequence Identity: 22% (21 aa)

QILSAASYLESNMICHLDLKLANCLVRGEEEDNP-------------HIVLCDFGSAVQFSD------------------------STMSTQWC
||.||  |. |. |.|.|||. | |.   ..|..              | ..||| | .| .                          . . .|
QICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFC
Kinase AqueK657.AA Ciliate-E2 123-236 18 1.2e-10 32.7 In-house 110-276 (365) Show / Hide 
Range on Protein: 123-236
Range on HMM: 110-276/365
Sequence Identity: 18% (34 aa)

FIVLDYHPQ-TLQEFLT-----------KEENKPVDFKIILSISSQILS---------------AASYLESNM-ICHLDLKLANCLVRGEEEDNPHIVLC
..|..|  . .|....            | . |. . | |. |. |||.               |  || |.  |.| |.|. | |.         | ..
YLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF---------IKII

DFGSAVQFSDSTMSTQ------WCHGLS---------------------LGGNRAHLCPELLS----------QYYSYK
||| . ...|.   ..      |.   .                     . |.   ..|| |.          ..|.||
DFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYK
Kinase AqueK657.AA TKL 123-229 20 9e-10 31.37 In-house 114-245 (364) Show / Hide 
Range on Protein: 123-229
Range on HMM: 114-245/364
Sequence Identity: 20% (28 aa)

FIVLDYHPQ-TLQEFLTKEENKPVDFKIILSISSQILSAASYLESNM--------ICHLDLKLANCLVRGEEE----------DNPHIVLCDFGSAVQFS
.|| .|.|  .| ..|.        .  ..... .| .. .|| |.         | | ||| .|.||    .          .. .. .|||| .  .|
CIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMS

DSTMSTQW--------------CHGLSLGGNRAHLCPELL
 |. .. .              ..  . .|. ... ||.|
QSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVL
Kinase AqueK657.AA C8 139-239 25 1.5e-09 29.43 In-house 114-214 (226) Show / Hide 
Range on Protein: 139-239
Range on HMM: 114-214/226
Sequence Identity: 25% (26 aa)

KEENKPVDFKIILSISSQILSAASYLESNMICHLDLKLANCLVRGEEEDNPHIVLCDFGSAVQFSDSTMSTQWCHGLSLGGNRAHLCPELLSQ-YYSYKT
........ .. . |  |..   .|...  | | |.|. | ||. ... .. | ||||| | | |..  . |  .  .. |. | . || ...    || 
RNKQQQFSKEMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYGFEIKLCDFGFASQVSKNKSHIQSKKMNTC-GTWAYFAPEIEKKQDNQYKQ

ST
..
YR
Kinase AqueK657.AA CMGC 123-210 15 2.5e-09 25.84 In-house 131-285 (513) Show / Hide 
Range on Protein: 123-210
Range on HMM: 131-285/513
Sequence Identity: 15% (24 aa)

FIVLDYHPQTLQEFLTKEE--------------------------NKPVDFKIILSISSQILSAAS--YLESNM--ICHLDLKLANCLVRGEEE------
..| .| ...| ... .                             |      |  .. ||| .    |. |.   |.| ||| .| |.  . |      
YLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKYCHSHWGNIIHRDLKPENILINHNCELITRMM

----------DNPHIVLCDFGSAVQFSDS-----------------------TMSTQ
          .| .. .||||.| ....                        .....
WKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHY
Kinase AqueK657.AA DAPK 156-197 40 3e-09 22.71 In-house 111-152 (264) Show / Hide 
Range on Protein: 156-197
Range on HMM: 111-152/264
Sequence Identity: 40% (17 aa)

QILSAASYLESNMICHLDLKLANCLVRGEEEDNPHIVLCDFG
|||..  .. |  |||.|||  |         ||.| . |||
QILDGVHHMHSKHICHFDLKPENIMLLDRNVPNPRIKIIDFG
Kinase AqueK657.AA STE 139-208 29 5.3e-09 28.04 In-house 143-217 (359) Show / Hide 
Range on Protein: 139-208
Range on HMM: 143-217/359
Sequence Identity: 29% (25 aa)

KEENKPVDFKIILSISSQILSA-ASYLESNMICHLDLKLANCLVRGEEEDNPHIVLCDFGSAVQFSDS--------------TMS
.. ..... ..|  |  ||| .  .||.|. | | |.| || |.         . ||||| . |..||              ||.
QH-QHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL---------VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQ
Kinase AqueK657.AA Trio 156-201 41 6e-09 18.39 In-house 103-148 (258) Show / Hide 
Range on Protein: 156-201
Range on HMM: 103-148/258
Sequence Identity: 41% (19 aa)

QILSAASYLESNMICHLDLKLANCLVRGEEEDNPHIVLCDFGSAVQ
|.|.|  || .. | |||.|  | ..       | | .||||.|.|
QMLEAVHYLHNCHILHLDIKPENMMMWHYNAGRPQIKICDFGDAQQ
TyrKc AqueK657.AA TyrKc 15-339 14 1.6e-05 -133.26 SMART 1-280 (280) Show / Hide 
Range on Protein: 15-339
Range on HMM: 1-280/280
Sequence Identity: 14% (54 aa)

FLISHLLSADQHGIVVASYCRVAGHPFPSKLYAVKLIFNFTDDDYSSSVLSNHFENEWLLLSSL-PPHPQIIKY--WCQFVS------VIPMEFVECCPQ
    . |   . |.|.    .           ||| . . .            | .|  ....| . || |..    |   .        .|  .| .| 
ITLGKKLGEGAFGEVYKGTWK--------IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH

EVCKSFPKDKHFTRKGQFIVLDYHPQTLQEFLTKEENKPVDFKIILSISSQILSAASYLESNMICHLDLKLANCLVRGEEEDNPHIVLCDFGSAVQFSDS
  .|.. .... .                          .  |  ||.. || .  .||.|. . | ||   ||||  .     ..  .|||        
GDLKDYLRKHRPK--------------------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFG--------

TMSTQWCHGLSLGGNRAHLCPELLSQ-YY----SYKTSTSRLQQPSAAPI------SLAQRLLCYKGQPSFAV-----GVLLYEVGSCGEHPLPD-----
                  |. .. .        .|...... .  .  ||      ..  .  ..    ...      ||...|. . |. | |.     
------------------LSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKF----TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQM

YPLNYMKEGVVTYGESDIAEL--PGAY----CHQQYFDLLKSLIACDPKQRPNLEHTLDTI
 .   . | | . .  .. .   |       |..  ... |.  . ||..||. .   . .
MSNQEVIEYVKQGYRMPQPPNDYP--MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase AqueK657.AA TKL 265-339 19 0.030703 3.88 In-house 273-364 (364) Show / Hide 
Range on Protein: 265-339
Range on HMM: 273-364/364
Sequence Identity: 19% (18 aa)

FAVGVLLYEVGSCGEHPLPDYPLNYMK---------EGVVTYGESDIAE---------LPGAYCHQQYFDLLKSLIACDPKQRPNLEHTLDTI
.. |..|.|. .. . |  ||| . |.         ..|.  |.               |  .| ... .|..   . ||..||. .  |...
YSFGIVLWEILTRCR-PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase AqueK657.AA Pkinase 316-339 34 1.880971 2.68 Pfam 268-293 (293) Show / Hide 
Range on Protein: 316-339
Range on HMM: 268-293/293
Sequence Identity: 34% (9 aa)

DLLKSLIACDPKQRPNLEHTLDT--I
|..|.... |||.||. |. |    .
DFIKWCLCKDPKKRPTAEQILQHPWF