Gene GTF2F1 (Human)

GTF2F1

Species: Human
Alias: GTF2F1
External Links:
Annotation:

Classification

Group: Atypical
Family: GTF2F1

Sequence

Name Sequence Type Origin Length Description Download
GTF2F1.AA Protein None 517 None Fasta, JSON
GTF2F1.NA RNA None 1554 None Fasta, JSON

Protein domain

Protein domains of GTF2F1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
TFIIF_alpha GTF2F1.AA TFIIF_alpha 1-517 45 6.1e-297 997.55 Pfam 1-626 (626) Show / Hide 
Range on Protein: 1-517
Range on HMM: 1-626/626
Sequence Identity: 45% (284 aa)

M-----------------------AAL---GPSS--QNVTEYVVRVPKNTTK-KYNIMA-------FNAADKVNFATWN---QARLERDLSNKKIYQEEE
|                       ...   .||.  ..|.||.|||||||.| ||..|.       |||.|||.|..||   |.|.||....||.|||||
MDLYGSNCKHMTLCAKCGKTMAQNRSKCHTCPSKPTRLVREYNVRVPKNTDKIKYHVMRFMTGLPDFNAMDKVDFNKWNIDSQVRMERENNQKKMYQEEE

MPESGAGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKSG--RKFKGIKKGGVTENTSYYIFTQCPDGA-FEAFPVHNWYNFTPLARHRTLTAE
|||.||||||||..|||||||||||..|..||.||||.||||||.|  |.|.|...||..||..||.|..||||| |||.|||.||||.|.|....||||
MPEYGAGSEFNRAQREEARRKKYGIISKKYRPDDQPWILRVNGKEGGQRQFRGHREGGQSENATYYVFMHCPDGAEFEAYPVHEWYNFNPVAQYKQLTAE

EAEEEWERRNKVLNHFSIMQQRRLKDQ-----DQDEDEE---EKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKK-----APLAKGGR
||||||.||.|..|||......|.|..     |..|..|   .|...||.|  .|.|||.|||..|..|.||...|......|.|||     ...||...
EAEEEWKRRKKTMNHFQRWMMKRAKNGPAAFGDHWEMTEQEGQKGGGGRSK--DLKIHDMEDDDWMDGDESDKGDEDEDEEKKKKKKSDDDAKKHAKNKK

K-----KKKKKGSDDEAFE-DSDDGDFEGQEVDYMSDGSSSSQEEPE-------------------------SKAKAPQQEEGPKGVDEQSDSSEESEEE
|     ||||.|.||.||| ||||||..|.|.|||||.|.|......                         .....|..||..|...||....||.|||
KNYDDDKKKKRGGDDDAFEYDSDDGDDWGHEYDYMSDDSASGNDPEAKVNKEMQSVAEEDALRKLLTSDEDSEREDKPSDEEPEKQEIEQNEDEEEKEEE

KPPEEDKEEEEEKKAPTPQEKKRRK--DSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKP-SGGSSRGNSRPGTPSAEGGSTSSTLRAAASKLEQG
|..|||||....|||..|..||..|  |.|...|.|..||||.|.|....|.||....|.|... |..||.|||||..||.|..........|||...|.
KNEEEDKESKKKKKAKKPKKKKNEKDKDDSDDDDDSDDSDIDDEDSVPFMMQKKQKEKKKEEPVDSNPSSPGNSRPARPSPEQKDSKNKRKMAASNMPQT

KR----VSEMPA---AKRLRLDTGPQSLSGKSTPQPPSG--------------KTTPNSGDVQVTEDAVRRYLT-RKPMTTKDLLKKFQTKKTGLSSEQT
.|    .|.||.   ||.......|.| |.|||||..||              |...|..|..|||.||||||. |||||||.||.||..|.||.|.|..
DRTGNDNSNMPISTPAKKVKMENAPKSSSKKSTPQTFSGSNTPPRGAEPASAPKSSSNKADYPVTEEAVRRYLMQRKPMTTKELLHKFKNKCTGMSCEEM

VNVLAQILKRLNPERKMINDKMHFSLKD
||..||||||.||..|.|..||.|.|| 
VNQMAQILKRINPVQKTIQHKMYFVLKE