CDC7_a

Species: S.moellendorffii
Alias: CDC7_a
External Links:
Annotation:

Classification

Group: Other
Family: CDC7

Sequence

Name Sequence Type Origin Length Description Download
CDC7_a.AA Protein None 275 None Fasta, JSON
CDC7_a.NA RNA None 828 None Fasta, JSON
CDC7_a.kin_dom Protein Kinase Domain None 179 None Fasta, JSON

Protein domain

Protein domains of CDC7_a.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase CDC7_a.AA CDC7 160-188 68 1.1e-15 41.91 In-house 128-156 (522) Show / Hide
Range on Protein: 160-188
Range on HMM: 128-156/522
Sequence Identity: 68% (20 aa)

NIIHRDVKPGNFLYSRKSKVGHLVDFNLA
.||||||||.||||.|..| . |||| ||
GIIHRDVKPSNFLYNRRTKKFLLVDFGLA

Kinase CDC7_a.AA Pkinase 73-185 21 1.7e-13 48.78 Pfam 50-156 (293) Show / Hide
Range on Protein: 73-185
Range on HMM: 50-156/293
Sequence Identity: 21% (27 aa)

EIKLLKLFGGKHSIIRLEEVIRDGEKKYLVLEHVEYD----SIQ-----SLKKDI--SMNDLRSYGFHLFKALNYMHQKVGLFFFFFVNTVFTFELLQNI
||...| .. .. |.|| .. .|. . |.|.|..| .    .       . .. .  |......|   ....|.|.|..                   .|
EIQIMKRLNHPN-IVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSM-------------------GI

IHRDVKPGNFLYSRKSKVG---HLVDF
||||.|| |.|....  ..   .. ||
IHRDLKPENILIDNNGHIDACVKICDF

Kinase CDC7_a.AA S_TKc 10-254 19 2.1e-10 -24.2 SMART 1-231 (231) Show / Hide
Range on Protein: 10-254
Range on HMM: 1-231/231
Sequence Identity: 19% (55 aa)

YRIEGVEGSGAYSVVFKARRFGDGRLFAIKCALFLCIFFGPGLLLTILTGPLQGDKIAASVDKEIKLLKLFGGKHSIIRLEEVIRDGEKKYLVLEHVEY-
|.|  . |.||...|.|.|  ..||..|||.                            .. .||..||   .   |..| .|..| .. |.|.|...  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGD

--DSIQSLKKD--------ISMNDLRSYGFHLFKALNYMHQKVGLFFFFFVNTVFTFELLQNIIHRDVKPGNFLYSRKSKVGHLVDFNLALVRFYSF---
  |  . .||         ..  . |.|   ...||.|.|.                   ..|||||.|| | | ..   .  . || || .  ..|   
LGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHS-------------------HGIIHRDLKPENILLDE---HIKICDFGLARQL-TTFCGT

-------IIWMLTF-------------VIARNRISLEGLKVSILLAIYSSNLWK--VLYVIRKTAK--PKQTDAMQ----SASRHYF
       ..   ..               .  .   .     ..  |  |   |  .    .|  .  |   .|.|     ..  .|
PWYMAPEVL-GYGKCKCDWWSCGCILYEMLCGYPPFP-QMQMMFKKIG-SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase CDC7_a.AA CK2 10-140 28 2.6e-10 26.2 In-house 1-114 (288) Show / Hide
Range on Protein: 10-140
Range on HMM: 1-114/288
Sequence Identity: 28% (38 aa)

YRIEGVEGSGAYSVVFKARRFGDGRLF--AIKCALFLCIFFGPGLLLTILTGPLQGDKIAASVDKEIKLLKLFGGKHSIIRLEEVIRDGEKKYL--VLEH
| ..   |.| || ||...           ||                ||  | .  ||      ||| |.   |   ||.| ....|   |    | |.
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIK----------------ILK-PVKKKKIK----REIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEY

VEYDSIQSLKKDISMNDLRSYGFHLFKALNYMHQK
|.   .. | . ..  |.| | | | ||| | | .
VNNTDFRQLYQTLTDYDIRYYMFELLKALDYCHSM

Kinase CDC7_a.AA CMGC 73-140 15 1.2e-08 23.53 In-house 71-201 (513) Show / Hide
Range on Protein: 73-140
Range on HMM: 71-201/513
Sequence Identity: 15% (20 aa)

EIKLLKLFG---------------GKHS-IIRLEEVIRDGE-----------------KKYLVLEHVEYDSIQSLKKD----------------------
|||.|| .                 .|  |..| ..... .                 . ||| |....|  | .|.                       
EIKILKHLNKNHDPNWQRRDDPDNKHHNNIVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHR

--------ISMNDLRSYGFHLFKALN--YMHQK
        ... . | | . ....|.  |.|..
RPPHNIKYFMI-HIR-YMYQILRGLKLKYCHSH

Kinase CDC7_a.AA CDC7 72-140 23 5.1e-08 18.48 In-house 57-127 (522) Show / Hide
Range on Protein: 72-140
Range on HMM: 57-127/522
Sequence Identity: 23% (17 aa)

KEIKLLKLFGGKHSIIRLEEVIRDGEKKYLVLEHVEYDSIQSLKKDIS--MNDLRSYGFHLFKALNYMHQK
.|. .| . ||.| .. . . .|  ..  .|... ...| | .  . .  |   ..|   ||.|| . ||.
NELQCLTRMGGHHNVMGMCCCFRYNDHVHIVMPYFPHCSFQDFYFHMNRDMEEIKHYMYNLFYALRHVHQF

Kinase CDC7_a.AA AGC 10-40 21 1e-06 11.85 In-house 1-37 (395) Show / Hide
Range on Protein: 10-40
Range on HMM: 1-37/395
Sequence Identity: 21% (8 aa)

YRIEGVEGSGAYSVVFKARRF------GDGRLFAIKC
...  | | |... |. .|.       . |...|.|.
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKV

Kinase CDC7_a.AA CDK 73-140 22 1e-06 16.93 In-house 58-127 (284) Show / Hide
Range on Protein: 73-140
Range on HMM: 58-127/284
Sequence Identity: 22% (18 aa)

EIKLLKLFGGKHSIIRLEEVIRDG-----------EKKYLVLEHVEYD--SIQSLKKDISMNDLRSYGFHLFKALNYMHQK
||.|||     . |..| .|. .             | |.| |....|  .. .          ..| . | ..|.|.|..
EISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD---------IKCYMWQLLRGLHYCHSN

Kinase CDC7_a.AA CAMKK 100-172 18 2e-06 15.69 In-house 105-228 (396) Show / Hide
Range on Protein: 100-172
Range on HMM: 105-228/396
Sequence Identity: 18% (23 aa)

YLV-LEHVEYDSIQSLK--KD--------------------------ISMND---------------------LRSYGFHLFKALNYMHQKVG--LFFFF
|.| .| .|. .|...   |                           .| .                      ...|  .  |.| |.|....  .    
YMVQMEYCERGQIMWWPYWKQDYQPNWPYQYTELYSNRQYQNKDFSIMSEQQSISEFINQVVKQDQYFIHEDYAWKYFRDCIKGLEYLHNYQKACSYIII

FVNTVFTFELLQNIIHRDVKPGNFL
..|        | ||||| || | |
YINEFI-IDHFQDIIHRDIKPQNIL

Kinase CDC7_a.AA Ciliate-E2a 10-39 30 3e-06 14.53 In-house 1-30 (275) Show / Hide
Range on Protein: 10-39
Range on HMM: 1-30/275
Sequence Identity: 30% (9 aa)

YRIEGVEGSGAYSVVFKARRFGDGRLFAIK
|... . |.|.. .|..|.. ..|  ||.|
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMK

Kinase CDC7_a.AA CMGC 10-39 27 4e-06 15.03 In-house 1-44 (513) Show / Hide
Range on Protein: 10-39
Range on HMM: 1-44/513
Sequence Identity: 27% (12 aa)

YRIEGVEGSGAYSVVFKARR--------------FGDGRLFAIK
| | .. |.|.|.||.|.|                 .... |||
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIK

Kinase CDC7_a.AA CAMK1 10-40 32 8e-06 12.9 In-house 1-34 (276) Show / Hide
Range on Protein: 10-40
Range on HMM: 1-34/276
Sequence Identity: 32% (11 aa)

YRIEGVEGSGAYSVVFKARRFG---DGRLFAIKC
| .  . |.|| |.|... .     .|. .||||
YEFGKEIGRGAFSEVYLCTHKETQTNGKQYAIKC

Kinase CDC7_a.AA Pkinase 10-40 35 1e-05 21.32 Pfam 1-31 (293) Show / Hide
Range on Protein: 10-40
Range on HMM: 1-31/293
Sequence Identity: 35% (11 aa)

YRIEGVEGSGAYSVVFKARRFGDGRLFAIKC
|.|... |||....|.|... |.|...|.|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKI

Kinase CDC7_a.AA RCK 10-40 38 2.1e-05 12.81 In-house 1-31 (298) Show / Hide
Range on Protein: 10-40
Range on HMM: 1-31/298
Sequence Identity: 38% (12 aa)

YRIEGVEGSGAYSVVFKARRFGDGRLFAIKC
| |    | |.|..|.||... .| . |||.
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKK

Kinase CDC7_a.AA TyrKc 10-261 13 3.2e-05 -138.13 SMART 1-280 (280) Show / Hide
Range on Protein: 10-261
Range on HMM: 1-280/280
Sequence Identity: 13% (45 aa)

YRIEGVEGSGAYSVVFKARRFGDGRLFAIKCALFLCIFFGPGLLLTILTGPLQGDKIAASVDKEIKLLKLFGGKH-SIIRLEEVIRDG-------EKKYL
 . . . |.||. .|.|..     .  |.|.    .                      .   .|..... .||.|  |.||  |....       |  ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA---------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMI

VLEHVEY----DSIQSLKKDISMNDLRSYGFHLFKALNYMHQKVGLFFFFFVNTVFTFELLQNIIHRDVKPGNFLYSRK----------SKVGHLV----
|.|....    | ... .....| || |. .   .  .| |.|                   |.||||    | |....          |. ..      
VMEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSK-------------------NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG

---DFNLA----LVRFYSFIIWMLTFVIARNR------------------ISLEGLKVSILLA--IYSSNLWKVLYVIRKTAKPKQ---------TDAM-
   |   .      ..   | ||   .| . .                   .. .   .      .  . . . .   .   .|.          .|.| 
ESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMY

---------QSASRHYFHRGTERL
         . ..|  |    |..
QIMKQCWHEDPEDRPTFSEIHECF

Kinase CDC7_a.AA AGC 159-182 42 3.5e-05 7.76 In-house 172-194 (395) Show / Hide
Range on Protein: 159-182
Range on HMM: 172-194/395
Sequence Identity: 42% (11 aa)

Q-NIIHRD-VKPGNFLYSRKSKVGHL
. .||||| .|| | |  ..   ||.
HMGIIHRDYLKPENILLDED---GHI

Kinase CDC7_a.AA Ciliate-E2 10-40 29 0.000347 10.25 In-house 1-31 (365) Show / Hide
Range on Protein: 10-40
Range on HMM: 1-31/365
Sequence Identity: 29% (9 aa)

YRIEGVEGSGAYSVVFKARRFGDGRLFAIKC
| .  . |.|....|.|...  ....||||.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKI

Kinase CDC7_a.AA CK2 161-188 42 0.000495 7.09 In-house 116-143 (288) Show / Hide
Range on Protein: 161-188
Range on HMM: 116-143/288
Sequence Identity: 42% (12 aa)

IIHRDVKPGNFLYSRKSKVGHLVDFNLA
|.|||||| | .   . ..  |.|  ||
IMHRDVKPHNIMIDHEKRKLRLIDWGLA

Kinase CDC7_a.AA CAMK1 159-177 52 0.000976 6.67 In-house 127-145 (276) Show / Hide
Range on Protein: 159-177
Range on HMM: 127-145/276
Sequence Identity: 52% (10 aa)

QNIIHRDVKPGNFLYSRKS
..| ||| || | ||. |.
KGIVHRDLKPENLLYYDKD

Kinase CDC7_a.AA RCK 71-140 25 0.001167 7.16 In-house 45-124 (298) Show / Hide
Range on Protein: 71-140
Range on HMM: 45-124/298
Sequence Identity: 25% (21 aa)

DKEIKLLKLFG-GKHSIIRLEEVIRDGE--KKYLVLEHVE---YDSIQS---LKKDISMND--LRSYGFHLFKALNYMHQK
..||| |. .   .. || | ||||| .    |.|.|...   |  ...    .| .. |   .... . ....|..|| .
LREIKSLRKLNPHPN-IIKLKEVIRDNDTYQLYFVFEYMDMNLYQMMKDFKERRKYLPENQRSIKNIMYQILQGLAHMHKH

Kinase CDC7_a.AA Ciliate-E2 159-188 41 0.001934 7.65 In-house 179-203 (365) Show / Hide
Range on Protein: 159-188
Range on HMM: 179-203/365
Sequence Identity: 41% (13 aa)

QN-IIHRDVKPGNFLYSRKSKVGHLVDFNLA
.| ||||| || | |.        ..|| |.
KNNIIHRDIKPENILF------IKIIDFGLS

Kinase CDC7_a.AA Ciliate-E2a 159-178 42 0.002483 5.69 In-house 121-141 (275) Show / Hide
Range on Protein: 159-178
Range on HMM: 121-141/275
Sequence Identity: 42% (9 aa)

QNIIHRDVKPGNFLYS-RKSK
.||.||| || |.|.  ....
RNIMHRDLKPENILFKNCSKN

Kinase CDC7_a.AA Ciliate-E2 86-140 16 0.003976 6.56 In-house 94-179 (365) Show / Hide
Range on Protein: 86-140
Range on HMM: 94-179/365
Sequence Identity: 16% (14 aa)

IIRLEEVIR--DGEKKYLVLEHVEYDSIQS-LKKD-------------ISMNDLRSYGFHLFK---------------ALNYMHQK
||.. |.    | .. |||.| ... . .. .|.              ....  . .  ....               ||.|.|.|
IIKMYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSK

Kinase CDC7_a.AA CAMKK 10-39 29 0.008721 4.17 In-house 1-31 (396) Show / Hide
Range on Protein: 10-39
Range on HMM: 1-31/396
Sequence Identity: 29% (9 aa)

YRIEGVEGSGAYSVVFKARRFGD-GRLFAIK
|..  . |.|.. .| .|.. .| ....|||
YELMKEIGQGQFGKVKLAYNEYDTQKHYAIK

Kinase CDC7_a.AA CMGC 159-170 57 0.013978 3.26 In-house 201-214 (513) Show / Hide
Range on Protein: 159-170
Range on HMM: 201-214/513
Sequence Identity: 57% (8 aa)

QN--IIHRDVKPGN
..  ||||| || |
HWGNIIHRDLKPEN

Kinase CDC7_a.AA CDK 10-40 33 0.014192 3.87 In-house 1-36 (284) Show / Hide
Range on Protein: 10-40
Range on HMM: 1-36/284
Sequence Identity: 33% (12 aa)

YRIEGVEGSGAYSVVFKARRFGDG-----RLFAIKC
| .    | |.| ||.|||   .|     .. |.|.
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKK

Kinase CDC7_a.AA CDK 159-176 44 0.01884 3.47 In-house 127-144 (284) Show / Hide
Range on Protein: 159-176
Range on HMM: 127-144/284
Sequence Identity: 44% (8 aa)

QNIIHRDVKPGNFLYSRK
..|.||| || | |....
NWIMHRDLKPQNILINNN

Kinase CDC7_a.AA CDC7 10-27 38 0.048911 0.21 In-house 1-18 (522) Show / Hide
Range on Protein: 10-27
Range on HMM: 1-18/522
Sequence Identity: 38% (7 aa)

YRIEGVEGSGAYSVVFKA
|...   |.| .|.|.||
YKVHDKIGEGTFSSVYKA

Kinase CDC7_a.AA RCK 159-174 37 0.109222 0.8 In-house 124-139 (298) Show / Hide
Range on Protein: 159-174
Range on HMM: 124-139/298
Sequence Identity: 37% (6 aa)

QNIIHRDVKPGNFLYS
... |||.|| | ...
HGFFHRDLKPENIMCT