CG11573_Dmel MES---------------------------------------------------------
DDR2_Mmus MIP------------IPRM-------------------------PLVLLLLLLILGS-A-
DDR1_Mmus MGT------------GTLS-------------------------SLLLLLLLVTIGD-AD
F11D5.3_Cele MKL-------------------------------------------LLYLFGVTFHS-N-
C25F6.4_Cele MQI-------------------------------------------ALVLLAIYGTT-T-
DDR2_Hsap MIL------------IPRM-------------------------LLVLFLLLPILSS-A-
DDR1_Hsap MGP------------EALS-------------------------SLLLLLL-VASGD-AD
DDR_Spur MTE------------LT-------------------------------HLRFTAECQ-SL
AqueK255_Aque M-----------------------------------------------------------
AqueK256_Aque ------------------------------------------------------------
AqueK257_Aque S-----------------------------------------------------------
AqueK258_Aque MNP------------VRLL----------------------------LSAILIQFSLQTK
AqueK259_Aque MSD------------TSLDNSLKLTERNIHILVVALVLALFVGVLFIVL-LIVCIRY--K
AqueK260_Aque MYYYLCLAVSQVMAGQANV-------------------------VFILTLLIVSVSS--Q
AqueK261_Aque MAG------------QANV-------------------------VFILTLLIVSVSS--Q
AqueK262_Aque MES------------TLKL----------------------------LFAVFSAAAILL-
CG11573_Dmel --------------------GAIADFQITASSAHDMGNV--------GPQHARLK-----
DDR2_Mmus --KAQVNPAIC-RYPLGMSGGHIPDEDITASSQWS-EST--------AAKYGRLD-----
DDR1_Mmus -MKGHFDPAKC-RYALGMQDRTIPDSDISVSSSWS-DST--------AARHSRLE-----
F11D5.3_Cele -TVVALELREC-SHQLGMSNRKIRDEQISASSSFDLQST--------GPQHARAH-----
C25F6.4_Cele -T-NTLRIDQCGENALGMQNGDIADSQITASSSFDKQSV--------GPQNARLH-----
DDR2_Hsap --KAQVNPAIC-RYPLGMSGGQIPDEDITASSQWS-EST--------AAKYGRLD-----
DDR1_Hsap -MKGHFDPAKC-RYALGMQDRTIPDSDISASSSWS-DST--------AARHSRLE-----
DDR_Spur -MSSVEVISTC-RYPLGMNDKAIKDEQLSASSVYE-NNTLS-----FGPQNARLH-----
AqueK255_Aque ------------------------------------------------------DSLNGQ
AqueK256_Aque ------------------------------------------------------------
AqueK257_Aque ----AVYDVTN-PASFDGSNLTTTDP--NCPT--L-VVCFNSTSKLINGDFGPMDSLNGQ
AqueK258_Aque -VPPTNYLITP-PTSYTGSSFTSDC--TLGDARGL-TRC-PNTTRLTDNVTSEGMAF--V
AqueK259_Aque KRTESVDEVLS-T-----EEKTIA------------------------------------
AqueK260_Aque -IS-TLYDVIN-SSPFNESNLTTTDPNSNCAAMNL-KNCFGNTSKLTDRDFGPMDSFNGQ
AqueK261_Aque -IS-tLYDVIN-SSPFNESNLTTTDPNSNCAAMNL-KNCFGNTSKLTDRDFGPMDSFNGQ
AqueK262_Aque ------FTNVS-SAPIKE------------------------------------------
CG11573_Dmel ---------------------------------IDNNGGAWCPKHMV--SRG------LT
DDR2_Mmus ---------------------------------SEEGDGAWCPEIPV--QPDD-----LK
DDR1_Mmus ---------------------------------SSDGDGAWCPAGPV--FPK------EE
F11D5.3_Cele ---------------------------------QESGSGAWCPKNQI--NSL------SK
C25F6.4_Cele ---------------------------------SELASGAWCPKPQI--NSK------SY
DDR2_Hsap ---------------------------------SEEGDGAWCPEIPV--EPDD-----LK
DDR1_Hsap ---------------------------------SSDGDGAWCPAGSV--FPK------EE
DDR_Spur ---------------------------------LNQGAGAWCPVNAQPESS-G-----HY
AqueK255_Aque LGKFFAFSQNNSRVTFQVTTST-RVSTVVLYFFNSPADGIGLPQLKV--LQSI-----SL
AqueK256_Aque ------------------------------------------------------------
AqueK257_Aque LGKFFAFSQNNSRVTFQVTTST-RVSTVVLYFFNSPADGIGLPQLKV--LQSI-----SL
AqueK258_Aque TDNFMGWNRS-FDLEFNFGTENFFFTRIDIYYYNNPSGGYGLPDIRT--SISRTGLEDSY
AqueK259_Aque ------------------------------------------------------------
AqueK260_Aque LGRFFAFNQNDSRLTF--TAFS-AVSTVVLYFFNSPADGIGLPQLEV--ILSG-----N-
AqueK261_Aque LGRFFAFNQNDSRLTF--TAFS-AVSTVVLYFFNSPADGIGLPQLEV--ILSG-----N-
AqueK262_Aque -----------------------------------------------------------M
CG11573_Dmel EYLQVDLLGVHLVSAIRTQGRFGKGQGQEYTE-----------AYVIEYWRPGLKKWIRW
DDR2_Mmus EFLQIDLRTLHFITLVGTQGRHAGGHGIEFAP-----------MYKINYSRDG-SRWISW
DDR1_Mmus EYLQVDLRRLHLVALVGTQGRHAGGLGKEFSR-----------SYRLRYSRDG-RRWMDW
F11D5.3_Cele EWLQISFSVDTVITSVETQGRFDDGRGMEYAT-----------AFKIQYWRPSLNAWASY
C25F6.4_Cele EFLQVTLNDTFLITSVETQGRYGNGTGREFAS-----------HYMIDYLRPG-SQWIRY
DDR2_Hsap EFLQIDLHTLHFITLVGTQGRHAGGHGIEFAP-----------MYKINYSRDG-TRWISW
DDR1_Hsap EYLQVDLQRLHLVALVGTQGRHAGGLGKEFSR-----------SYRLRYSRDG-RRWMGW
DDR_Spur EYLQVDLLNLTVILALSTQGRWDTNFGNEYTS-----------RFRLELSRDGGKTWIRY
AqueK255_Aque PPVPYFFSNNDELTLTDSQLRTVTLHLNQKLI-----------TVQIDFIFPS-NSRINW
AqueK256_Aque ------------------------------------------------------------
AqueK257_Aque PPVPYFFSNNDELTLTDSQLRTVTLHLNQKLI-----------TVQIDFIFPS-NSRINW
AqueK258_Aque TTVVCTFIDNSEISRSDDNVQVLSLVILTSESSPSLVLLVPYQYLRLQFIFSS-SFLATQ
AqueK259_Aque NEAPYCVESAEKTTVTSPSYH-V--ERHAPLV-----------TISHDIVGME-TNQ---
AqueK260_Aque KTIPYFFSNNDELTLTDSQLRTVTLQLNQSLS-----------TFQIDFIFPV-NSKINW
AqueK261_Aque KTIPYFFSNNDELTLTDSQLRTVTLQLNQSLS-----------TFQIDFIFPV-NSKINW
AqueK262_Aque KPVYTFGSNTTSLPIIVSMVCMV---------------NQSIDQVELRWIH---------
CG11573_Dmel RSLQGKEVLPGNI--NT-YSEVENVLQPSVFASKVRLYPYSQYDRTVCLRAEIVGCAWEE
DDR2_Mmus RNRHGKQVLDGNS--NP-YDVFLKDLEPPIVARFVRLIPVTDHSMNVCMRVELYGCVWLD
DDR1_Mmus KDRWGQEVISGNE--DP-GGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRD
F11D5.3_Cele KDDFELETIPANN--DT-EHAIRRHLDRAIIARRIRIVPVSNSTRTVCMRVEVFGCPFDD
C25F6.4_Cele KNRTGHVYMDGNF--DT-TTPVIRVLDPPIVASRIRFVPSSKNTRTVCMRAEIHGCKH-E
DDR2_Hsap RNRHGKQVLDGNS--NP-YDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLD
DDR1_Hsap KDRWGQEVISGNE--DP-EGVVLKDLGPPMVARLVRFYPRADRVMSVCLRVELYGCLWRD
DDR_Spur VQMTGEEVFVGNR--DT-NSQITVHISPPIVAQVLRIIPVVLIQTPVCMRIELYGCKWLD
AqueK255_Aque FLVSEVQLFAGSPVSAPMEDIVFKDGSISVVTLGPDN---IQSSISINCTVLNNGSFHWN
AqueK256_Aque ------------------------------------------------------------
AqueK257_Aque FLVSEVQLFAGSPVSAPMEDIVFKDGSISVVTLGPDN---IQSSISINCTVLNNGSFHWN
AqueK258_Aque TFISEIRFFTNTDTSFPAVPIVFMSPN---QTLQPHT---VQSSLNLSCTVDNNGTFHWT
AqueK259_Aque ------------------------------------------------------------
AqueK260_Aque FLVSEVQFFNDTLVPAPMEDIVFKDGSISVVTLGPDN---IQSSISINCTVLNNGSFHWN
AqueK261_Aque FLVSEVQFFNDTLVPAPMEDIVFKDGSISVVTLGPDN---IQSSISINCTVLNNGSFHWN
AqueK262_Aque ------------------------------------------DGITYSST-ENNSSG---
CG11573_Dmel GIVSY-SIPKGMQR-------GMDIDLSDKTYDGYEEG---D-HYVNGLGQLVDGQRGKD
DDR2_Mmus GLVSY-NAPAGQQFVLPG---GSIIYLNDSVYDGAV-G---YS-MTEGLGQLTDGVSGLD
DDR1_Mmus GLLSY-TAPVGQTMQLS----EVMVHLNDSTYDGYTAG---GL-QYGGLGQLADGVVGLD
F11D5.3_Cele SLVFY-NVDQGDLQ-------S-GISYHDFSYDGNLAN---SPHLTGGIGKLYDGEVGKN
C25F6.4_Cele GVTYYSTVPDGSRL-------D-TLDFKDSMFEDSQIYTESGIKRYGSWPANRRFRSAAS
DDR2_Hsap GLVSY-NAPAGQQFVLPG---GSIIYLNDSVYDGAV-G---YS-MTEGLGQLTDGVSGLD
DDR1_Hsap GLLSY-TAPVGQTMYLS----E-AVYLNDSTYDGHTVG---GL-QYGGLGQLADGVVGLD
DDR_Spur HLKSY-SMPTGDTR-------GEYV-FEDDTYDGYTFE---GQ-RMNGLGQLTDGMLGHS
AqueK255_Aque WLFNN-TIPITDELFVEDATRTSILNINGLSYSNEG-N---YT-CTANS-----------
AqueK256_Aque ------------------------------------------------------------
AqueK257_Aque WLFNN-TIPITDELFVEDATRTSILNINGLSYSNEG-N---YT-CTANS-----------
AqueK258_Aque WSGP---EVSTGDIKLADTTRTSILMISNVSADDAG-N---YT-CTAFY-----------
AqueK259_Aque -------------------------------------H---YH-CLRME-----------
AqueK260_Aque WLVNN-TIPITDELFIEDATRTSILYINGLSYSNEG-N---YT-CTANS-----------
AqueK261_Aque WLVNN-TIPITDELFIEDATRTSILYINGLSYSNEG-N---YT-CTANS-----------
AqueK262_Aque ---R---LSILNTTSSNDTSFTTTLTILPAMYTDNG-T---YY-CQVRD-----------
CG11573_Dmel NFRADI-NGLGKGYEWIGWRNDTLLGRPVEIIFEFETVRNLSAVIIHTNNMFSKDVQVFV
DDR2_Mmus DFTQTHEYHVWPGYDYVGWRNESATNGFIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
DDR1_Mmus DFRQSQELRVWPGYDYVGWSNQSFPTGYVEMEFEFDRLRTFQTMQVHCNNMHTLGARLPG
F11D5.3_Cele NVFVNH-------HKWVGWRRKR--NGNVKLAFEFSELRNISGILIHTSNEFKKSAKAFS
C25F6.4_Cele PFEKNQM-----NNSWIGWNRDT-TDGRITILFEFEEVHNFTDVVLATFG-----NRI-D
DDR2_Hsap DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
DDR1_Hsap DFRKSQELRVWPGYDYVGWSNHSFSSGYVEMEFEFDRLRAFQAMQVHCNNMHTLGARLPG
DDR_Spur NYRLS-PYNVPQGYEWVGWRNTSHPN--PEITFEFDSLRNFTSLGFHVNNYFTNNVEIFD
AqueK255_Aque ----------TA------------------------------------------------
AqueK256_Aque ------------------------------------------------------------
AqueK257_Aque ----------TA------------------------------------------------
AqueK258_Aque ----------LAFGDFVGPPNNVFN-----------------------------------
AqueK259_Aque ----------DG------------------------------------------------
AqueK260_Aque ----------TV------------------------------------------------
AqueK261_Aque ----------TV------------------------------------------------
AqueK262_Aque ----------KG------NSSSNWT-----------------------------------
CG11573_Dmel HAKVFFSIG-GRHFSG-EPVQFSYMPDLVLDHAR-DV-----------------------
DDR2_Mmus EVQCYFRSE-ASEWEP-TAVYFPLVLDDVNPSAR-FV-----------------------
DDR1_Mmus GVECRFKRGPAMAWEG-EPVRHALGGSLGDPRAR-AI-----------------------
F11D5.3_Cele SATVLFSIN-GKDFSD-TIVHFNNPEDTESEVPR-WI-----------------------
C25F6.4_Cele GIDVIFSQD-GKTFPLFSQISSSERQSLNNTSRRYDF-----------------------
DDR2_Hsap EVQCYFRSE-ASEWEP-NAISFPLVLDDVNPSAR-FV-----------------------
DDR1_Hsap GVECRFRRGPAMAWEG-EPMRHNLGGNLGDPRAR-AV-----------------------
DDR_Spur AIEVQFSIR-KGHFSP-RSIYTTIRPDSDHQDAR-WI-----------------------
AqueK255_Aque ------------------------------------------------------------
AqueK256_Aque ------------------------------------------------------------
AqueK257_Aque ------------------------------------------------------------
AqueK258_Aque ----------------------SIKPDMETTNSV-SLTLFINVSAEVYYDEFIVPAGNTV
AqueK259_Aque ------------------------------------------------------------
AqueK260_Aque ------------------------------------------------------------
AqueK261_Aque ------------------------------------------------------------
AqueK262_Aque ----------------------SARTNL---------HLLVHL-------NTVHPTVNAT
CG11573_Dmel TIKL-----------------------------------------------------HHR
DDR2_Mmus TVPL-----------------------------------------------------HHR
DDR1_Mmus SVPL-----------------------------------------------------GGH
F11D5.3_Cele RIPV-----------------------------------------------------NNR
C25F6.4_Cele RVPL-----------------------------------------------------HNR
DDR2_Hsap TVPL-----------------------------------------------------HHR
DDR1_Hsap SVPL-----------------------------------------------------GGR
DDR_Spur TVNL-----------------------------------------------------GNR
AqueK255_Aque ---------------------------------------------------------GST
AqueK256_Aque ------------------------------------------------------------
AqueK257_Aque ---------------------------------------------------------GST
AqueK258_Aque TVQKDTNVTLSCIFTGYLPMDYQINWMDS----SNMADGTITNGDDTRNI---SQSGGSS
AqueK259_Aque ---------------------------------------------------------GVD
AqueK260_Aque ---------------------------------------------------------GIV
AqueK261_Aque ---------------------------------------------------------GiV
AqueK262_Aque TSS--PAAELSCDMAGYVPPQSSLHWYRNGTRLTNTGRYSIVYRDGWRRAQKESKDGTS-
CG11573_Dmel LGR-------YVQLHLYFA--ARWMMISEITFISA-----------------PVVGNFTD
DDR2_Mmus MAS-------AIKCQYHFA--DTWMMFSEITFQSD-----------------AAMYNNSG
DDR1_Mmus VGR-------FLQCRFLFA--GPWLLFSEISFISD-----------------VV-NDSSD
F11D5.3_Cele IAK-------VAKIRLNFGTDSDWLFISEVNFESN-----------------HT-N--IE
C25F6.4_Cele AGR-------KVRISIKFS--SDWMFLTEVHFTSA-----------------ANLTLLSE
DDR2_Hsap MAS-------AIKCQYHFA--DTWMMFSEITFQSD-----------------AAMYNNSE
DDR1_Hsap VAR-------FLQCRFLFA--GPWLLFSEISFISD-----------------VV-NNSSP
DDR_Spur VAQ-------WLKVALVHR--GKWVLVSEVSFESE-----------------DIPD-NFD
AqueK255_Aque ASK-------IIQIRISSS--TS-----------N-----------------T-ISSSSA
AqueK256_Aque ------------------------------------------------------------
AqueK257_Aque ASK-------IIQIRiSSS--TS-----------N-----------------T-ISSSSA
AqueK258_Aque PGPAVQSNYTILSVEVDDS--DS-----------YTCSMDGT-RLKETISLIV-INSATI
AqueK259_Aque SPE-------SVT-----------------------------------------------
AqueK260_Aque SPV-------TSS-----------------------------------------------
AqueK261_Aque SPV-------TSS-----------------------------------------------
AqueK262_Aque --SSVLGVLVISSPTVQDS--GQ-----------YQCRIEGYCHLTRSVQLTV-KNGELK
CG11573_Dmel EL----ANGE---------------------------------------KQSVT---SEY
DDR2_Mmus ----ALPTSP---------------------------------------MAPTT---YDP
DDR1_Mmus ----TFPPAPWWPPGPPPTN------------------------FSSLELEPRG---QQP
F11D5.3_Cele LLND-------------------------------------------DVVIPDSVS-YFS
C25F6.4_Cele ----KIPP-------------------------------------------PSS------
DDR2_Hsap ----ALPTSP---------------------------------------MAPTT---YDP
DDR1_Hsap ALGGTFPPAPWWPPGPPPTN------------------------FSSLELEPRG---QQP
DDR_Spur TSTATYDTPVVGPPSAGPVDHTTVSTTDADHVIPQTGNGTQKPNLISSTKKAGG---GVS
AqueK255_Aque ----SIATATGTT-NSPAFT--TTS--------------------ITVAFIPSSTIIQTT
AqueK256_Aque ------------------------------------------------------------
AqueK257_Aque ----SIATATGTT-NSPAFT--TTS--------------------ITVAFIPSSTIIQTT
AqueK258_Aque ----SSTPVPMTTSSTPSMS--L----------------------TSTSSAPSS---SSS
AqueK259_Aque -------------------------------------------------SIPSPRVS-DE
AqueK260_Aque ----IMPT-------STSTK--T----------------------QSVTPAPTG---NTS
AqueK261_Aque ----IMPT-------STSTk--T----------------------QSVTPAPTG---NTS
AqueK262_Aque ----DRDEMICT-EGVVDI---L----------------------NTANNG-GS---NSS
CG11573_Dmel PLQRDEVGRAISSGGDLLILLI-QLLLPLIINVCSTPFMRSSHLPK--SPGRGSSPEFVV
DDR2_Mmus MLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFW---Q-KMLEKAS--RRMLDDEMTV
DDR1_Mmus VAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHW---R-RLLSKAE--RRVLEEELTV
F11D5.3_Cele VTEH-DDGTSMF---AFIIFFFMFLIVAVIILTVLY---R-KREYRVKASSPSPNAKREI
C25F6.4_Cele -----AATQQLL----VVCGIIFLTIFACVAY-CVS--------VCLK--RRQKNKSVDS
DDR2_Hsap MLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFW---Q-KMLEKAS--RRMLDDEMTV
DDR1_Hsap VAKAEGSPTAILIGCLVAIILLLLLIIALMLWRLHW---R-RLLSKAE--RRVLEEELTV
DDR_Spur NTPAQRSPIGTVISVVVTVLLLLVLLFALLLF--LY---R-RKYIKLK--HRLPTLAFEA
AqueK255_Aque PAVANGGLDTVVVGLSVSLGIVAFIIVGLILLTIVL--------VKCR--KRCANRSLQV
AqueK256_Aque ------------------------------------------------------------
AqueK257_Aque PAVANGGLDTVVVGLSVSLGIVAFIIVGLILLTIVL--------VKCR--KRCANRSLQV
AqueK258_Aque PSPQSGDPLPIIAGAAAAAVLLILIIIVSI--VIAV--------LYCK--RRSVSKTMVI
AqueK259_Aque YDYGNGGT----------------------------------------------------
AqueK260_Aque P----SSNTGLVIGLAVTIVLIVLLVIAVIVCIIIV--------IYCK--RKQKPFIKDA
AqueK261_Aque P----SSNTGLVIGLAVTIVLIVLLVIAVIVCIIIV--------IYCK--RKQKPFIKDA
AqueK262_Aque G-GDNNQLLTIIIAAVAGFLGLIVIILII---IIIA--------VACH--RCRRTDVFVQ
CG11573_Dmel A-TG-KVTASA------------------------------------------RNSLNAA
DDR2_Mmus S-LS-LPSESSMF-NNNRSSS-----PSEQ----------------------ESNSTYDR
DDR1_Mmus H-LS-VPGDTILI-NNRPGPRE---PPPYQEPRPRGTPPHSAPCVPNGSALLLSNPAYRL
F11D5.3_Cele L-LT-IDGNTIKH-HVSPS--------TYQMA----------------------------
C25F6.4_Cele N-VKK--DLIITHMGNKPTCHVF---PSN------------------G---KLSNGHYEV
DDR2_Hsap S-LS-LPSDSSMF-NNNRSSS-----PSEQ----------------------GSNSTYDR
DDR1_Hsap H-LS-VPGDTILI-NNRPGPRE---PPPYQEPRPRGNPPHSAPCVPNGSALLLSNPAYRL
DDR_Spur ---N-CNGGGATI-NNCPTIATMTTVPSR-----------------------RSNPTYQI
AqueK255_Aque P-MY-KISYNITA-NNKSSFRS------------------------------EGNDETDF
AqueK256_Aque ------------------------------------------------------------
AqueK257_Aque P-MY-KISYNITA-NNKSSFRS------------------------------EGNDETDF
AqueK258_Aque S-----------D--S-------------------------------------NNGLYAE
AqueK259_Aque ------------------SSQQ------------------------------TGREELLK
AqueK260_Aque P-LRTSIKYNVTD-LGQSKEEE------------------------------AGMEQYAV
AqueK261_Aque P-LRTSIKYNVTD-LGQSKEEE------------------------------AGMEQYAV
AqueK262_Aque PTGGATVTYLPAA-VD-------------------------------------NNEPEVK
CG11573_Dmel TLPLPSPPVPPPLE-------------------------------KYYA---------A-
DDR2_Mmus IFPL-RPDYQEP--SR------------------------------L---------IRK-
DDR1_Mmus LL----ATYARP--PR------------------------------G---P-----GPP-
F11D5.3_Cele -RDN---------LQN-----------------------------AL---------IEK-
C25F6.4_Cele A--ND-ILYARSQKST-----------------------------L----------LSV-
DDR2_Hsap IFPL-RPDYQEP--SR------------------------------L---------IRK-
DDR1_Hsap LL----ATYARP--PR------------------------------G---P-----GPP-
DDR_Spur THPDDEPQYHVI--DN-----------------------------MM---------VES-
AqueK255_Aque IPENDIPLFQRNTLTD-----------------------------VL-------------
AqueK256_Aque ------------------------------------------------------------
AqueK257_Aque IPENDIPLFQRNTLTD-----------------------------VL-------------
AqueK258_Aque LSKPEPPPLPSRIADNGG--------------------------YASIDIPGNGFPLNDI
AqueK259_Aque PH------LPLK-GT-----------------------------CYSLEVP---------
AqueK260_Aque VHKEQPPPIPPQNFSA-----------------------------VEYDVIEL--KETN-
AqueK261_Aque VHKEQPPPIPPQNFSA-----------------------------VEYDVIEL--KETN-
AqueK262_Aque IED-PPPPVPMRTHSQSGSYTKSGRSAELPDLLQRSQTHQLPSSTVQYDVPTTGAPEGN-
CG11573_Dmel ----------------TPV------------SS---------------------------
DDR2_Mmus ----------------LPE------------FAP--------------------------
DDR1_Mmus ----------------TPA------------WAK--------------------------
F11D5.3_Cele ----------------M-------------------------------------------
C25F6.4_Cele ------------------------------------------------------------
DDR2_Hsap ----------------LPE------------FAP--------------------------
DDR1_Hsap ----------------TPA------------WAK--------------------------
DDR_Spur ----------------EDE------------L----------------------------
AqueK255_Aque ------------------------------------------------------------
AqueK256_Aque ------------------------------------------------------------
AqueK257_Aque ------------------------------------------------------------
AqueK258_Aque HSPLPPAFTPQHTSPDRPTPAQISLKP---TFLQ--------------------------
AqueK259_Aque ------------------------------------------------------------
AqueK260_Aque ----------------KPKLAQISTFA---GFQ----MI---------------------
AqueK261_Aque ----------------KPKLAQISTFA---GFQ----MI---------------------
AqueK262_Aque ----P-RVIPPERGGGGPPPVTA-RKPKRKTYYDSVNMLQSVAAASNGLPGASGISVQSV
CG11573_Dmel ---------------KP----MPVAPPGSQSS-------------------GSLSSSTTA
DDR2_Mmus GEE--ESGCSG-VV-KPAQ------PNGP-EGVPH----YAEADIVNLQ--GVTGGNTYC
DDR1_Mmus PTN--TQACSGDYM-EPEKPGAPLLPPPPQNSVPH----YAEADIVTLQ--GVTGGNTYA
F11D5.3_Cele -------------------------PMSP--IISD----YAEPDISVCS--DVT------
C25F6.4_Cele -SSKSTFSC---RAIPPTWTD-FNFPPPPEG----------------------REEHTYS
DDR2_Hsap GEE--ESGCSG-VV-KPVQ------PSGP-EGVPH----YAEADIVNLQ--GVTGGNTYS
DDR1_Hsap PTN--TQAYSGDYM-EPEKPGAPLLPPPPQNSVPH----YAEADIVTLQ--GVTGGNTYA
DDR_Spur -DN--VSESSRIYA-EPENPTCTY--KDKHNMLQH----YAETDLINIQ--GVSGNTIYG
AqueK255_Aque ----------------------------------------------------------YD
AqueK256_Aque ------------------------------------------------------------
AqueK257_Aque ----------------------------------------------------------YD
AqueK258_Aque PNP--MYASSENLD-RHFQPRE---YLQPTRSLPH----IADADEPRE---MGSQFNIYA
AqueK259_Aque --S--LFN------------------NGA-QILR-----------------------TYS
AqueK260_Aque DNA--LYD------------------KSPTVITGH----YSYA--------GDCEGDIYS
AqueK261_Aque DNA--LYD------------------KSPTVITGH----YSYA--------GDCEGDIYS
AqueK262_Aque PSP--HDVLSGSLQ-RQDAQNP-------PDLHPIYQDGFTEEDLAPYNVVDNDYDQIYS
CG11573_Dmel ATTPTS--------GVVGVGKPHHY-------------------NLDMSAN-------FA
DDR2_Mmus VPAVTM------------------------------------------------DL-LSG
DDR1_Mmus VPALPP------------------------------------------------GA-VGD
F11D5.3_Cele ------------ANTPLLYGIDGPY-------------------DTQKRSNPLSSMVKYS
C25F6.4_Cele QPVSPE------------------------------------------------NS-SNG
DDR2_Hsap VPAVTM------------------------------------------------DL-LSG
DDR1_Hsap VPALPP------------------------------------------------GA-VGD
DDR_Spur VPSQCM------------------------------------------------EK-LNN
AqueK255_Aque IPDIPEETN------P---------------------------------PADDDDV-IYA
AqueK256_Aque ------------------------------------------------------------
AqueK257_Aque IPDIPEETN------P---------------------------------PADDDDV-IYA
AqueK258_Aque KPNLVPPPV------PPYRGTPDPDDGIFTDEDINPEALKRQSFNMDSSIYGGYRA-IYN
AqueK259_Aque EAHIDYEK-DSNYSPPLYT-RSN-----------------------------S-------
AqueK260_Aque EPQWKSEKDELNVNNPIYYGKTDPF-------------------KFTESADYIDGA-IYA
AqueK261_Aque EPQWKSEKDELNVNNPIYYGKTDPF-------------------KFTESADYIDGA-IYA
AqueK262_Aque EPIEPATML------------------SIS---------EREAH-DEG---LPYSA-IYD
CG11573_Dmel DINEE-RANCQVQEFPRQSLVIVEKLGSGVFGELHLCETNVLNDLTE------FDSHCSA
DDR2_Mmus -------KDVAVEEFPRKLLAFKEKLGEGQFGEVHLCEVEGMEKFKDKDFAL-DVSANQP
DDR1_Mmus -------G-PPRVDFPRSRLRFKEKLGEGQFGEVHLCEVEDPQDLVSSDFPI-SVHKGHP
F11D5.3_Cele DYGE--VYCTTLPEIARDKLICVSRIGQGEFGEVDLCQLEN-------------------
C25F6.4_Cele SYKSV-RKIQALKKYPSSALLIGKAIGEGKFTMIKECIIFG------------------G
DDR2_Hsap -------KDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFAL-DVSANQP
DDR1_Hsap -------G-PPRVDFPRSRLRFKEKLGEGQFGEVHLCEVDSPQDLVSLDFPL-NVRKGHP
DDR_Spur -------SRTCCPEYPRSQLNFLELLGEGMFGEVHLCEAEDIQDYIRNGFPFENKNKGER
AqueK255_Aque KPK-----VNKVMRIKNESFEEIALLGTGQFGEVVLAKTIGLSL-KDLRLDKTDDDKFAT
AqueK256_Aque -------------------VKIISELGVGQFGKVFLAHTTTI-----------------S
AqueK257_Aque KPK-----VNKVMRIKNESFEEIALLGTGQFGEVVLAKTIGLSL-KDLRLDKTDDDKFAT
AqueK258_Aque DPQPLQRSENELLEVKEKNIRELKDLGMGQFGVVVLAHTVSLSL-KQLGMSESNNDPGVS
AqueK259_Aque TSSS---LNLTIIEIEPSNIVTDGTLGMGQFGQVHLAHTRGLSA-ADIGIG-TDSDRTRS
AqueK260_Aque EPSK---VLNTITEVTIDNLNVIEMLGVGNFGEVILATTIDLSL-KDLRLSSTNDDRSIS
AqueK261_Aque EPSK---VLNTITEVTIDNLNVIEMLGVGNFGEVILATTIDLSL-KDLRLSSTNDDRSIS
AqueK262_Aque DPKPL-AAAESLLQVTSDNVIEIRKLGNGQFGQVILARTRHLSL-VDMKLSETLTDRSQS
. :* * * : .
CG11573_Dmel TLVAVATLRPGANDHL------RKEFRSKAKQLAQ-LSDPNVARLVGACLR--DEPICIV
DDR2_Mmus VLVAVKMLRADANKNA------RNDFLKEIKIMSR-LKDPNIIRLLAVCIT--EDPLCMI
DDR1_Mmus LLVAVKILRPDATKNA------RNDFLKEVKIMSR-LKDPNIIRLLGVCVQ--DDPLCMI
F11D5.3_Cele RKVAVKKLHGIS-QAD------EFSFHREIRVLGS-LKHPNVVEVVGVCTI--QKPILCI
C25F6.4_Cele LKCAHKSTKEEDCVHG------TRALGDEIACLLQCGRHPRIVELFGVD-----ESYNLL
DDR2_Hsap VLVAVKMLRADANKNA------RNDFLKEIKIMSR-LKDPNIIHLLAVCIT--DDPLCMI
DDR1_Hsap LLVAVKILRPDATKNASFSLFSRNDFLKEVKIMSR-LKDPNIIRLLGVCVQ--DDPLCMI
DDR_Spur TLVAVKMLRKDASKNA------RADFMKEMKIMSQ-LRDPNIVRLLAACTE--DEPYCMI
AqueK255_Aque VRVAVKKIRENQSDES------IIALKKEIKFMSQ-LDHNNVVRLLAVSAESCQEQF-IV
AqueK256_Aque VLVAVKVLHSDADELE------RETFEKEVKFMSR-IKHENIIQILGVCLK--KNSF-IM
AqueK257_Aque VRVAVKKIRENQSDES------IIALKKEIKFMSQ-LDHNNVVRLLAVSAESCQEQF-IV
AqueK258_Aque LVVAIKRLRAEADDKM------REMFEKEVKFMAR-LRHENVVRLLGVCLS--KNAF-IM
AqueK259_Aque HEVAVKFLNQNATEKD------LKCFQKEVKYMSR-LRHRNVVQILAVCWR--EEKF-IM
AqueK260_Aque IKVAVKKVREDQDKMA------LEAFQKEVKFMSQ-LDHDNVVRLLAVSAESCQEQF-IV
AqueK261_Aque IKVAVKKVREDQDKMA------LEAFQKEVKFMSQ-LDHDNVVRLLAVSAESCQEQF-IV
AqueK262_Aque ILVAIKKLKTNAETGL------LEAFDKEVKFMSR-LNHDNVVRLLAVCTV--GEHF-IM
* . : : : . .: .:... . :
CG11573_Dmel QDYSHCLGDLNQFLQEHVAETS-G--------LMAKKSLSFGCLVYIATQIASGMKHLEQ
DDR2_Mmus TEYME-NGDLNQFLSRHEPLSSC---------S-SDATVSYANLKFMATQIASGMKYLSS
DDR1_Mmus TDYME-NGDLNQFLSARQLENKATQGLSGDTESDQGPTISYPMLLHVGAQIASGMRYLAT
F11D5.3_Cele MEYME-NGDLKSYILKNP-------------------TIQTSQCISICTQLAAGLAYLES
C25F6.4_Cele LEHVE-YGCIRNFWMAS------------------EAPLDTEFLVRICKDIYSAMAYLES
DDR2_Hsap TEYME-NGDLNQFLSRHEPPNSS---------SSDVRTVSYTNLKFMATQIASGMKYLSS
DDR1_Hsap TDYME-NGDLNQFLSAHQLEDKAAEGAPGDGQAAQGPTISYPMLLHVAAQIASGMRYLAT
DDR_Spur VEYME-NGDLNQFLYEREGFEVGLNNCNANLSNCNKSSISVGALVYKSTQIASGMKYLSN
AqueK255_Aque MEYME-NGDLNKFLMDHSFTD-SH--------PPEENELSPNILLSFCIQVANGMSYLSS
AqueK256_Aque MEYME-NGDLNQYLQKFEYSPD-------------------DQVVYIALQVAGGMRYLAG
AqueK257_Aque MEYME-NGDLNKFLMDHSFTD-SH--------PPEENELSPNILLSFCIQVANGMSYLSS
AqueK258_Aque MEYME-NGDLNHYLRNMDLIEDIN--------PLPEGAVSLPVLIYICLQVARGMCYLAS
AqueK259_Aque LEFMK-NGDLQTFLQCYKSVNMGQ--------ETYNKTLSYYKLVDMSLQIADAMRYLSS
AqueK260_Aque MEYME-NGDLNQHLLNHTFTE-SH--------PPPESYLSPNILLSMCIQIANGMSYLAS
AqueK261_Aque MEYME-NGDLNQHLLNHTFTE-SH--------PPPESYLSPNILLSMCIQIANGMSYLAS
AqueK262_Aque MEYME-NGDLNQFLQKHTLVPDTV-------TGLGDWEITPIILLYIGVQISSGMHYLGS
:. . * :. . :: .: :*
CG11573_Dmel MNFVHRDLATRSCIIGPELCVKVCS-IGTVINRSAYASDYCQLEGFTGRQSQPMPIRWMA
DDR2_Mmus LNFVHRDLATRNCLVGKNYTIKIAD-FG--MSRNLYSGDYYRIQGR-----AVLPIRWMS
DDR1_Mmus LNFVHRDLATRNCLVGENFTIKIAD-FG--MSRNLYAGDYYRVQGR-----AVLPIRWMA
F11D5.3_Cele CNFVHRDIAARNCLVDGEGNVKIAD-FG--MARSLYSQEYYKVEGK-----FVLPIRWMA
C25F6.4_Cele IRIVHGHFTPNNILMDGEFHAKVCSPRG--PSHH-------------------AQLRYSA
DDR2_Hsap LNFVHRDLATRNCLVGKNYTIKIAD-FG--MSRNLYSGDYYRIQGR-----AVLPIRWMS
DDR1_Hsap LNFVHRDLATRNCLVGENFTIKIAD-FG--MSRNLYAGDYYRVQGR-----AVLPIRWMA
DDR_Spur MNFVHRDLANRNCLVGKSYTIRIAD-FG--MSRNLYSSNYYRIEGR-----AVLPIRWMA
AqueK255_Aque RNFLHRDLASRNLLVGPDYLVKVGD-FG--LSRNLYDSSYYKVSGK-----AKMPLRWMA
AqueK256_Aque QNYVHRDLATRNCLVGQKFLVKIAD-FG--MSRQLYDNNYYRIRGR-----AMLPIRWMA
AqueK257_Aque RNFIHRDLASRNILVGPDYIVKVGD-FG--LSRNLYDSSYYKVSGK-----AKMPIRWMA
AqueK258_Aque LRFIHRDLATRNILVGQDFKVKIAD-FG--MSQNLYSDFYYRIQGR-----AILPIRWMA
AqueK259_Aque CKFIHRDLAARNCLVGDNFLVKVAD-FG--LSKNLYDSCYYRLTGA-----AILPIRWMA
AqueK260_Aque CNYIHRDLATRNILVGRDNVVKVGD-FG--LSRNLYDSVYYKVSGK-----AKMPIRWMS
AqueK261_Aque CNYIHRDLATRNILVGRDNVVKVGD-FG--LSRNLYDSVYYKVSGK-----AKMPIRWMS
AqueK262_Aque RRFVHRDLATRNCLVGKDFIVKISD-FG--MSRRLYESAYYRVQGT-----LVLPIRWMA
. :* .:: .. ::. . :: . * : :*: :
CG11573_Dmel WESVLLGKFTTKSDVWSFAVALWEILTFAREQPYEHLSDKSVIENIGLIYRDYKMHELLP
DDR2_Mmus WESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQIYLP
DDR1_Mmus WECILMGKFTTASDVWAFGVTLWEVLMLCRSQPFGQLTDEQVIENAGEFFRDQGRQVYLS
F11D5.3_Cele WEALLLGKFSTASDVWGFGVTMWEIFSLCSEKPYSDMTDDDVVENLQSMSSTGSLKQVLS
C25F6.4_Cele PESIVNNEFTHKSDAWAVATTVYEMAYQCRQRPYEELTNEQIVDNACALLDHQPNAVVPL
DDR2_Hsap WESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLP
DDR1_Hsap WECILMGKFTTASDVWAFGVTLWEVLMLCRAQPFGQLTDEQVIENAGEFFRDQGRQVYLS
DDR_Spur WESILLGKFTSKTDVWAFGVTLWEVMMLCREQPYSRLTDEQVIENTGQFFEKDGTPVYLA
AqueK255_Aque KEC-FYGKFSEVTDLWAFGVTVWELYMMSRDYPYSFMTDQEVLDNALKG----FNCVLLE
AqueK256_Aque KEC-FYGRFTEKTDVWAYGVVMWEIFTLCQCQPYETLNDQEVIDNALAG----PERKLLS
AqueK257_Aque KEC-FYGKFSEVTDLWAFGVTVWEIYMMSRDYPYSFMTDQEVIDNALKG----FNCVLLE
AqueK258_Aque NEC-FYGRFSEKTDVWSFGVLMWEIFTLCKLQPFERMTDQEVIDDAIKG----SERTLPY
AqueK259_Aque PEC-FYGRFSEKSDVWGFGVTLWEMFNLCLERPYTNMKDKQIIEGALNG----SL-KVLD
AqueK260_Aque TEC-FYGKFSEKSDVWAYGIMVWEVYNMSRDVPYHQLTDAEVLDDALKG----QYRVLPT
AqueK261_Aque TEC-FYGKFSEKSDVWAYGIMVWEVYNMSRDVPYHQLTDAEVLDDALKG----QYRVLPT
AqueK262_Aque CET-FYGKFSVKSDTWAFGVTLWEVYTLAMCDPYDEMSDEEVIQDAIRG----PNRKLLP
* . ..*: :* *. . ::* . *: :.: .:::.
CG11573_Dmel MPPNCPREIYDLMC-ECWQRDESSRPSFREIHLYLQRKNLG-FK----------------
DDR2_Mmus QPALCPDSVYKLML-SCWRRETKHRPSFQEIHLLLLQQ----------------------
DDR1_Mmus RPPACPQTLYELML-RCWSREPEQRPPFAQLHRFLADDA---------------------
F11D5.3_Cele RPRMCPSKLYNEQILPCWNYESSRRPSFENVHLHLQSLVH--T-----------------
C25F6.4_Cele MPTVFNYEILQLLT-RCFRVDQLERPTFERLVKPF-------------------------
DDR2_Hsap QPAICPDSVYKLML-SCWRRDTKNRPSFQEIHLLLLQQ----------------------
DDR1_Hsap RPPACPQGLYELML-RCWSRESEQRPPFSQLHRFLAEDA---------------------
DDR_Spur KPPQCPKDIHNLMK-RCWTSEPGQRPTFDFLHTFLQARNI-GY-----------------
AqueK255_Aque KPETCPERVFSVLVKLCWSK---ERKTFAQVHKELVHADQRLYQ----------------
AqueK256_Aque QPVSCSNDAYDIML-RCWVDDPEARASFEELQIH--------------------------
AqueK257_Aque KPETCPERVFSVIVKLCWSK---ERKTFAQVHKELVHADQRLYQ----------------
AqueK258_Aque QPQACPNEVYSVML-DCWIHEPEERASFQQIYDLLSSIHA--------------------
AqueK259_Aque KPECCQTDLYHIMT-SCWRPRAVDRPSFEELHKRLST-----------------------
AqueK260_Aque RPTTCPQAVYNIIKKLCWEYQTEERGGFADIYSSLVNVEKTLYSISAVYDVTNPASFDGS
AqueK261_Aque RPTTCPQAVYNIIKKLCWEYQTEERGGFADIYSSLVNVEK--------------------
AqueK262_Aque KPEACPREVYDVML-RCWVHDPAMRADFGEIYSRLYMTYT--------------------
* *: * * :
CG11573_Dmel ------------------------------------------------------------
DDR2_Mmus ------------------------------------------------------------
DDR1_Mmus ------------------------------------------------------------
F11D5.3_Cele ------------------------------------------------------------
C25F6.4_Cele ------------------------------------------------------------
DDR2_Hsap ------------------------------------------------------------
DDR1_Hsap ------------------------------------------------------------
DDR_Spur ------------------------------------------------------------
AqueK255_Aque ------------------------------------------------------------
AqueK256_Aque ------------------------------------------------------------
AqueK257_Aque ------------------------------------------------------------
AqueK258_Aque ------------------------------------------------------------
AqueK259_Aque ------------------------------------------------------------
AqueK260_Aque NLTTTDPNCPTLVVCFNSTSKLINGDFGPMDSLNGQLGKFFAFSQNNSRVTFQVTTSTRV
AqueK261_Aque ------------------------------------------------------------
AqueK262_Aque ------------------------------------------------------------
CG11573_Dmel ------------------------------------------------------------
DDR2_Mmus ------------------------------------------------------------
DDR1_Mmus ------------------------------------------------------------
F11D5.3_Cele ------------------------------------------------------------
C25F6.4_Cele ------------------------------------------------------------
DDR2_Hsap ------------------------------------------------------------
DDR1_Hsap ------------------------------------------------------------
DDR_Spur ------------------------------------------------------------
AqueK255_Aque ------------------------------------------------------------
AqueK256_Aque ------------------------------------------------------------
AqueK257_Aque ------------------------------------------------------------
AqueK258_Aque ------------------------------------------------------------
AqueK259_Aque ------------------------------------------------------------
AqueK260_Aque STVVLYFFNSPADGLGLPQLKVLQSLSLPPVPYFFSNNDELTLTDSQLRTVTLHLNQKLL
AqueK261_Aque ------------------------------------------------------------
AqueK262_Aque ------------------------------------------------------------
CG11573_Dmel -----------------------------------PQTHTHMY
DDR2_Mmus ----------------------------------------GAE
DDR1_Mmus ---------------------------------------LNTV
F11D5.3_Cele -------------------------------------SPHIHF
C25F6.4_Cele -----------------------------------------QD
DDR2_Hsap ----------------------------------------GDE
DDR1_Hsap ---------------------------------------LNTV
DDR_Spur -------------------------------------EPPVSL
AqueK255_Aque -----------------------------------YCDVLHWN
AqueK256_Aque ----------------------------------------AYD
AqueK257_Aque -----------------------------------YCDVLHWN
AqueK258_Aque --------------------------------------YNDFS
AqueK259_Aque ----------------------------------------LYH
AqueK260_Aque TVQLDFLFPSNSRLNWFLVSEVQLFAGKLLNVWLMYYYLLLNR
AqueK261_Aque ---------------------------------------TLYS
AqueK262_Aque ---------------------------------------SQAV