Protein (view, download) , Domain (view, download)
p38g_Hsap_p38                      YRDLQ--PVGSGAYGAVC-SAV--DG-R------TGAKVAIKKLY--RPFQSELFAKRAY
p38d_Hsap_p38                      YVSPT--HVGSGAYGSVC-SAI--DK-R------SGEKVAIKKLS--RPFQSEIFAKRAY
p38b_Hsap_p38                      LQGLR--PVGSGAYGSVC-SAY--DA-R------LRQKVAVKKLS--RPFQSLIHARRTY
p38a_Hsap_p38                      YQNLS--PVGSGAYGSVC-AAF--DT-K------TGLRVAVKKLS--RPFQSIIHAKRTY
NLK_Hsap_nmo                       IEPDR--PIGYGAFGVVW-SVT--DP-R------DGKRVALKKMP--NVFQNLVSCKRVF
JNK3_Hsap_JNK                      YQNLK--PIGSGAQGIVC-AAYD--A-V------LDRNVAIKKLS--RPFQNQTHAKRAY
JNK2_Hsap_JNK                      YQQLK--PIGSGAQGIVC-AAFD--T-V------LGINVAVKKLS--RPFQNQTHAKRAY
JNK1_Hsap_JNK                      YQNLK--PIGSGAQGIVC-AAYD--A-I------LERNVAIKKLS--RPFQNQTHAKRAY
Erk7_Hsap_ERK7                     YLLRR--QLGQGAYGIVW-KAV--DR-R------TGEVVAIKKIF--DAFRDKTDAQRTF
Erk5_Hsap_ERK5                     YEIIE--TIGNGAYGVVS-SARR--R-L------TGQQVAIKKIP--NAFDVVTNAKRTL
nmo_Dmel_nmo                       VQPDR--PIGYGAFGVVW-AVT--DP-R------DGRRVALKKLP--NVFQSLVSSKRVF
CG2309_Dmel_ERK7                   FDVRK--RMGKGAYGIVW-KAT--DR-R------TKNTVALKKVF--DAFRDETDAQRTY
P38c_Dmel_p38                      YEFVR--FLGGGSFGQVA-KVR--LR-G------TENYFAMKRLM--RPFEREEDAKGTY
Mpk2_Dmel_p38                      YQDLQ--PVGSGAYGQVS-KAV--VR-G------TNMHVAIKKLA--RPFQSAVHAKRTY
p38b_Dmel_p38                      YQNLQ--PVGQGAYGQVC-KAV--VR-G------TSTKVAIKKLA--RPFQSAVHAKRTY
bsk_Dmel_JNK                       YINLR--PIGSGAQGIVC-AAYD--T-I------TQQNVAIKKLS--RPFQNVTHAKRAY
rl_Dmel_ERK1                       YIKLA--YIGEGAYGMVV-SADD--T-L------TNQRVAIKKIS---PFEHQTYCQRTL
p38g_Mmus_p38                      YQDLQ--PVGSGAYGAVC-SAV--DS-R------TGNKVAIKKLY--RPFQSELFAKRAY
p38d_Mmus_p38                      YLAPA--HVGSGAYGAVC-SAI--DK-R------TGEKVAIKKLS--RPFQSEIFAKRAY
p38b_Mmus_p38                      LQGLR--PVGSGAYGSVC-SAY--DA-R------LRQKVAVKKLS--RPFQSLIHARRTY
p38a_Mmus_p38                      YQNLS--PVGSGAYGSVC-AAF--DT-K------TGHRVAVKKLS--RPFQSIIHAKRTY
NLK_Mmus_nmo                       IEPDR--PIGYGAFGVVW-SVT--DP-R------DGKRVALKKMP--NVFQNLVSCKRVF
JNK3_Mmus_JNK                      YQNLK--PIGSGAQGIVC-AAYD--A-V------LDRNVAIKKLS--RPFQNQTHAKRAY
JNK2_Mmus_JNK                      YQQLK--PIGSGAQGIVC-AAFD--T-V------LGINVAVKKLS--RPFQNQTHAKRAY
JNK1_Mmus_JNK                      YQNLK--PIGSGAQGIVC-AAYD--A-I------LERNVAIKKLS--RPFQNQTHAKRAY
ERK7_Mmus_ERK7                     YLIKR--RLGKGAYGIVW-KAM--DR-R------TGEVVAIKKIF--DAFRDQIDAQRTF
ERK5_Mmus_ERK5                     YEIIE--TIGNGAYGVVS-SARR--R-L------TGQQVAIKKIP--NAFDVVTNAKRTL
ERK4_Mmus_ERK3                     FIDFQ--PLGFGVNGLVL-SATD--S-R------ACRKVAVKKIV----LSDARSMKHAL
ERK3_Mmus_ERK3                     YMDLK--PLGCGGNGLVF-SAVD--N-D------CDKRVAIKKIV----LTDPQSVKHAL
ERK2_Mmus_ERK1                     YTNLS--YIGEGAYGMVC-SAYD--N-L------NKVRVAIKKIS---PFEHQTYCQRTL
ERK1_Mmus_ERK1                     YTQLQ--YIGEGAYGMVS-SAYD--H-V------RKTRVAIKKIS---PFEHQTYCQRTL
pmk-3_Cele_p38                     PNSIE--YLGGGSFGNVI-KTSAVCR-D-----GLRRYVAIKKMR--EPFFDPHHARRIF
pmk-2_Cele_p38                     YNSLK--PLGEGAYGVVC-TAE--YE-P------TGDRVAIKKFF--RPFQSTIHAKRTY
pmk-1_Cele_p38                     YINLT--PIGTGAYGTVC-AAE--CT-R------SGTRVAIKKFN--RPFQSIIHARRTY
mpk-1_Cele_ERK1                    YVNLS--YIGEGAYGMVA-SALD--T-I------TRDRVAIKKIS---PFEHQTFCQRTL
lit-1_Cele_nmo                     SQPDR--PIGYGAFGVVW-SVT--DP-R------SGKRVALKKMP--NVFQNLASCKRVF
jnk-1_Cele_JNK                     YQNLR--LIGSGAQGIVC-SAFD--T-V------RNEQVAIKKLS--RPFQNVTHAKRAY
F09C12.2_Cele_MAPK-Unclassified    YLAQE--NLGAGAFGVVC-RAID--S-K------LNKQVAIKKIT--RVFKNQSTAKCAL
C49C3.10_Cele_JNK                  FQFDK--P-------FVV-HAFD--Q-V------LGRPVVIKKVMLPDSLHDRQPWRRAQ
C05D10.2_Cele_ERK7                 FDLQK--RLGKGAYGIVW-KAY--DK-R------SRETVALKKIF--DAFRNPTDSQRTF
C04G6.1_Cele_MAPK-Unclassified     YLAEE--NVGAGAYGVVC-KAMD--T-R------NKKQVAIKKIP--RAFTAHTLAKRSL
SMK1_Scer_ERK1                     YEIIQ--FLGKGAYGTVC-SVKFKGR-S------PAARIAVKKIS--NIFNKEILLKRAI
SLT2_Scer_ERK1                     FQLIK--EIGHGAYGIVC-SARFAEA-A------EDTTVAIKKVT--NVFSKTLLCKRSL
KSS1_Scer_ERK1                     YKLVD--LIGEGAYGTVC-SAIH--K-P------SGIKVAIKKIQ---PFSKKLFVTRTI
HOG1_Scer_p38                      YNDLN--PVGMGAFGLVC-SAT--DT-L------TSQPVAIKKIM--KPFSTAVLAKRTY
FUS3_Scer_ERK1                     FQLKS--LLGEGAYGVVC-SATH--K-P------TGEIVAIKKIE---PFDKPLFALRTL
Erk4_Hsap_ERK3                     FVDFQ--PLGFGVNGLVL-SAVD--S-R------ACRKVAVKKIA----LSDARSMKHAL
Erk3_Hsap_ERK3                     YMDLK--PLGCGGNGLVF-SAVD--N-D------CDKRVAIKKIV----LTDPQSVKHAL
Erk2_Hsap_ERK1                     YTNLS--YIGEGAYGMVC-SAYD--N-V------NKVRVAIKKIS---PFEHQTYCQRTL
Erk1_Hsap_ERK1                     YTQLQ--YIGEGAYGMVS-SAYD--H-V------RKTRVAIKKIS---PFEHQTYCQRTL
T07A9.3_Cele_JNK                   YVNLS--FLNAGAQGTVV-MADD--L-V------TTQRVAIKKMQ--QPFVMTMSAKRAY
W06B3.2_Cele_MAPK-Unclassified     YEPTQ--NIGSGAFGIVC-EAVE--T-S------SNQKVAIKKVA--HASATPTLARRTL
Y51B9A.9_Cele_JNK                  NRYVDLLPSQFG-NAMEV-IAFD--Q-I------SERRVVIKKVVLPENFDNWQHWRRAQ
ZC416.4_Cele_JNK                   YVNLK--FLNVGAQGIVV-MADD--L-V------TTQRVAIKKMQ--QPFLLTMSARRAY
YKL161C_Scer_ERK1                  FHLTG--KIGRGSHSLIC-SSTYTES-N------EETHVAIRKIP--NAFGNKLSCKRTL
Erk1_Ddis_ERK                      YSIVK--CIGHGAYGVVC-SAKD--N-L------TGEKVAIKKIS--KAFDNLKDTKRTL
Erk2_Ddis_ERK7                     YEVLQ--KIGKGAYGIVW-KAI--DK-K------TKQTVALKKIF--DAFQNATDAQRTF
13785_Tthe_ERK                     YRILK--QIGFG-FNPTF-TAID--Q-E------YGQKVIIEVIK--IENDDLIYMNQLI
18504_Tthe_ERK                     YSIID--SIGQGAYGIVV-AARD--L-NCQ--DEENNLVAIKKIE--KAFEHKIFTKRTL
18512_Tthe_ERK                     YRILE--KIGQGAYGVVS-AAID--Q-V------KRKSVAIKKIE--KAFDQRIYTKRTL
18725_Tthe_ERK                     YEYIK--QIGYGAYGVVC-SAVN--K-E------NGSKVAIKKVQ--NAYDDLIDAKRIV
23186_Tthe_ERK                     YQLLV--PIGIGGYGVVA-KAFD--Q-E------KQDFVAIKKIF--KPFLNPLETKRIL
4173_Tthe_ERK                      YQIVK--RIGDGAYGVVF-KAID--K-S-----KNNEIVAIKKVS--DAFLDPRDAKRIL
6784_Tthe_ERK                      YEFHK--QIGHGAYGVVC-SGVD--T-K------CNKKIAIKKIT--NAFEDLVDAKRIV
28107_Tthe_ERK                     ---------GQGTFGVVV-ACQD--K-EKEFFDEDSDFVAIKKIE--RAFEHTQYAIRTI
27541_Tthe_ERK7                    FEIIQ--KIGKGAYGIVW-KAI--DR-K------LRQVVAVKKVF--DAFHNPTDAQRTF
28942_Tthe_ERK7                    FEIIQ--KLGKGAYGIVW-KAF--CK-K------SKQIVALKKVF--DAFHNATDAQRTF
3210_Tthe_ERK7                     YEILS--KLGRGAYGIVW-KVY--DK-R------TKQVLALKKIF--DAFQNSTDAQRTF
11145_Tthe_MAPK-Unclassified       YTYSG--YIGQGGYSQVY-KFID--N-Q------TNQPVAIKFV---NLFHNEQDTKRVL
16370_Tthe_MAPK-Unclassified       YDLIK--VVGSGSYGSVA-EATD--K-K------SGKKVAIKRLN--GIFEDNVDCKRIL
23757_Tthe_ERK                     YEVDK--LLGSGAYGQVV-RAK--DK-K-----NQNQYVAIKKLH--K-IEDVIDAKRVL
13784_Tthe_ERK                     ------------------------------------------------------------
17883_Tthe_ERK                     YQILR--LIWRDTNISFCLAAID--R-E------YGQKVFIKVIK--LEECILKYIIQAI
ERK5_Spur_ERK5                     YKPLE--KIGTGAYGVVC-SAIN--K-K------NGEKVAIKKIP--NSFDELTTAKRTF
ERK3_Spur_ERK3                     FCDLR--PLGYGSSGTVF-SAVD--S-E------CDKSVAIKRVS----LTDKKSCKSAL
ERK1_Spur_ERK1                     YTELE--AIAQGALALCS-SAVD--T-R------HGGKVAIKKIS---PFEHQTYCQRTL
ERK7_Spur_ERK7                     ------------------------------------------------------------
JNK_Spur_JNK                       YKNLK--SVGSGAQGLVV-AAYD--V-L------TNQSVAIKKLS--RPFQNVTHAKRAY
NLK_Spur_nmo                       --------------------VT--DP-R------DGKRVALKKMP--HVFQNLISCKRVY
p38_Spur_p38                       YVRLE--PVGSGAYGQVC-STEAEDTRQ------KGLRVAIKKLS--RPFQTVIHAKRTY
CC1G_02007_Ccin_ERK1               YEFVK--ELGQGAYGCVV-AARH--R-Q------TGEGCAIKKIT--NINTKRILTKRCL
CC1G_14865_Ccin_MAPK-Unclassified  -------------------SAAD--E-I------SGETVAIKMVT--RVFEKIQLAKRAL
CC1G_03633_Ccin_MAPK-Unclassified  YQLLH--AIGEGAYGTVA-AALH--K-P------TGRQVAIKKVL---PFDHTLFCLRTL
CC1G_07620_Ccin_MAPK-Unclassified  YQVLD--VVGEGAYGIVC-SAVH--R-P------SGRKVAIKKIA---PFEHSMFCLRTL
CC1G_00577_Ccin_MAPK-Unclassified  YVDLQ--PVGMGAFGLVC-SAK--DQ-L------TGASVAIKKIM--KPFSTPVLAKRTY
AqueK118_Aque_ERK1                 YSNLS--YIGEGAYGMVC-SAVD--N-Q------SLTKVAIKRIT---PFEHQTYCQRTL
AqueK119_Aque_ERK1                 YKDLE--YLALGGNGLVC-KAID--T-Y------TDKRVVISKRD--SLF-SKTYCQRDL
AqueK120_Aque_ERK1                 YRNLE--FLTKGSNGSMC-FATD--T-R------TSSRVVISKRD--GLY-SQEYSKRNL
AqueK121_Aque_ERK5                 YTPLE--SIGTGAYGVVC-AAKD--N-R------TGRKVAIKKIP--RAFDEVVTAKRTY
AqueK122_Aque_ERK7                 ------------------------------------------------------------
AqueK123_Aque_ERK7                 ------------------------------------------------------------
AqueK124_Aque_ERK7                 ------------------------------------------------------------
AqueK125_Aque_ERK7                 ------------------------------------------------------------
AqueK126_Aque_ERK7                 YDIKR--RIGKGAYGIVW-KSV--DR-R------TGEIVALKKIF--DAFANSTDAQRTF
AqueK127_Aque_JNK                  YQDLK--PLGHGAQGVVC-SAKD--S-V------RGERIAIKKLV--KPFQNETYAKRAF
AqueK128_Aque_nmo                  VELSH--PIGYGSFGVVW-SVK--NP-R------TGGLSALKRIP--RVFQSLLSCVRTF
AqueK129_Aque_p38                  YREIA--SIGTGAYGTVC-SAT--DT-H------YNIKVALKKLA--RPFQNHVHAKRTY
AqueK130_Aque_p38                  YQDMS--PIGIGGFSTVC-CAV--DS-E------TGEKVALKKLA--RPFQSPVHAKRAY
AqueK131_Aque_p38                  YQELT--PINSGAYGQVC-SAL--DT-K------YGIRVAIKKLY--APFEHRHNAKKAY
ERK-p2-2_Smoe_ERK1                 VPPIR--PIGRGAYGIVC-SAVN--S-E------TNEEVAIKKIG--NAFDNRIDAKRTL
ERK-Un_Smoe_ERK1                   YLLHE--HIGSGSYGDVC-RATD--C-Q------ASLTVALKRVG--DVLCCPLLAKRVL
ERK5_b_Smoe_ERK1                   YKVLE--VIGKGSYGVVC-SAID--T-R------TNEKVAIKKIN--DIFEHVSDATRIL
ERK-p1_a-2_Smoe_ERK1               ------------------------------------------------------------
ERK5_a-2_Smoe_ERK1                 YKILE--VIGKGSYGVVC-SATD--M-H------TGDKVAIKKIN--DIFEHVSDATRIL
ERK-p1_b-1_Smoe_ERK1               YAPIK--PIGKGAYGVVC-SATN--S-E------SGEKVAIKKIT--NAFENTTDARRTL
ERK7_Smoe_ERK1                     YHVCQ--KLGKGAYGIVW-KAF--DR-K------TNDVVALKKIF--DAFQNSTDAQRTF
ERK5_a-1_Smoe_ERK1                 YKILE--VIGKGSYGVVC-SATD--M-H------TGDKVAIKKIN--DIFEHVSDATRIL
ERK5_c_Smoe_ERK1                   YKVLE--VIGKGSYGVVC-SAID--T-R------TNEKVAIKKIN--DIFEHVSDATRIL
ERK-p2-1_Smoe_ERK1                 VPPIR--PIGRGAYGIVC-SAVN--S-E------TNEEVAIKKIG--NAFDNRIDAKRTL
ERK-p1_a-1_Smoe_ERK1               YVPIR--PLGKGAYGVVC-SADN--L-E------TGDKVAIKKIG--NAFENSIDALRTL
ERK-p1_b-2_Smoe_ERK1               YAPIK--PIGKGAYGVVC-SATN--S-E------SGEKVAIKKIT--NAFENTTDARRTL
GK037_Glam_ERK1                    YKVTK--ALGAGAYGVVA-EAVD--T-R------TNTTVAIKKIS--NLFVHLVDSKRTL
GK038_Glam_ERK7                    YEIIH--RVGKGAYGVVW-KAV--NR-K------TNETVALKKIF--QAFQNDTDAQRTF


p38g_Hsap_p38                      RELRLLKHMR------HENVIGLLDVFTPDE----------TLDDFTDFYLVMPFMGT-D
p38d_Hsap_p38                      RELLLLKHMQ------HENVIGLLDVFTPAS----------SLRNFYDFYLVMPFMQT-D
p38b_Hsap_p38                      RELRLLKHLK------HENVIGLLDVFTPAT----------SIEDFSEVYLVTTLMGA-D
p38a_Hsap_p38                      RELRLLKHMK------HENVIGLLDVFTPAR----------SLEEFNDVYLVTHLMGA-D
NLK_Hsap_nmo                       RELKMLCFFK------HDNVLSALDILQPP-----------HIDYFEEIYVVTELMQS-D
JNK3_Hsap_JNK                      RELVLMKCVN------HKNIISLLNVFTPQK----------TLEEFQDVYLVMELMDA-N
JNK2_Hsap_JNK                      RELVLLKCVN------HKNIISLLNVFTPQK----------TLEEFQDVYLVMELMDA-N
JNK1_Hsap_JNK                      RELVLMKCVN------HKNIIGLLNVFTPQK----------SLEEFQDVYIVMELMDA-N
Erk7_Hsap_ERK7                     REITLLQEFG-----DHPNIISLLDVIRAE--------------NDRDIYLVFEFMDT-D
Erk5_Hsap_ERK5                     RELKILKHFK------HDNIIAIKDILRPTV----------PYGEFKSVYVVLDLMES-D
nmo_Dmel_nmo                       RELKMLCFFK------HENVLSALDILQPP-----------HLDFFQEIYVITELLQS-D
CG2309_Dmel_ERK7                   REVIFLRAFR-----CHPNIVRLVDIFKAS--------------NNLDFYLVFEFMES-D
P38c_Dmel_p38                      REIRLLKHMN------HRNVISLLNVFHPPA---------HNMMEFQQVYLVTHLMDA-D
Mpk2_Dmel_p38                      RELRLLKHMD------HENVIGLLDIFHPHP-------ANGSLENFQQVYLVTHLMDA-D
p38b_Dmel_p38                      RELRLLKHMD------HENVIGLLDVFHPGQ-------PADSLDQFQQVYMVTHLMDA-D
bsk_Dmel_JNK                       REFKLMKLVN------HKNIIGLLNAFTPQR----------NLEEFQDVYLVMELMDA-N
rl_Dmel_ERK1                       REITILTRFK------HENIIDIRDILRV-----------DSIDQMRDVYIVQCLMET-D
p38g_Mmus_p38                      RELRLLKHMR------HENVIGLLDVFTPDE----------SLDDFTDFYLVMPFMGT-D
p38d_Mmus_p38                      RELLLLKHMH------HENVIGLLDVFTPAS----------SLRSFHDFYLVMPFMQT-D
p38b_Mmus_p38                      RELRLLKHLK------HENVIGLLDVFTPAT----------SIEDFSEVYLVTTLMGA-D
p38a_Mmus_p38                      RELRLLKHMK------HENVIGLLDVFTPAR----------SLEEFNDVYLVTHLMGA-D
NLK_Mmus_nmo                       RELKMLCFFK------HDNVLSALDILQPP-----------HIDYFEEIYVVTELMQS-D
JNK3_Mmus_JNK                      RELVLMKCVN------HKNIISLLNVFTPQK----------TLEEFQDVYLVMELMDA-N
JNK2_Mmus_JNK                      RELVLLKCVN------HKNIISLLNVFTPQK----------TLEEFQDVYLVMELMDA-N
JNK1_Mmus_JNK                      RELVLMKCVN------HKNIIGLLNVFTPQK----------SLEEFQDVYIVMELMDA-N
ERK7_Mmus_ERK7                     REIMLLKEFG-----GHPNIIRLLDVIPAK--------------NDRDIYLVFESMDT-D
ERK5_Mmus_ERK5                     RELKILKHFK------HDNIIAIKDILKPTV----------PYGEFRSVYVVLDLMES-D
ERK4_Mmus_ERK3                     REIKIIRRLD------HDNIVKVYEVLGPKGSDLQ-----GELFKFSVAYIVQEYMET-D
ERK3_Mmus_ERK3                     REIKIIRRLD------HDNIVKVFEILGPSGSQLTD--DVGSLTELNSVYIVQEYMET-D
ERK2_Mmus_ERK1                     REIKILLRFR------HENIIGINDIIRA-----------PTIEQMKDVYIVQDLMET-D
ERK1_Mmus_ERK1                     REIQILLRFR------HENVIGIRDILRA-----------PTLEAMRDVYIVQDLMET-D
pmk-3_Cele_p38                     RETKLLQLM------RHDNIICALDIYTPDE-----------ENDFRDVYVVTEFAGR-S
pmk-2_Cele_p38                     RELKLLRTLQ------HDNVLEMIDVFTPDP----------DASSLNNVYFVSVLMGS-D
pmk-1_Cele_p38                     RELRLLRCMC------HENIIDLLDVFTPNE----------NVNDIEDVYFVSMLMGA-D
mpk-1_Cele_ERK1                    REIKILNRFK------HENIINIQEIIRS-----------ETVDSLKDIYIVQCLMET-D
lit-1_Cele_nmo                     REIKMLSSFR------HDNVLSLLDILQPA-----------NPSFFQELYVLTELMQS-D
jnk-1_Cele_JNK                     RELKLMSLVN------HKNIIGILNCFTPQK----------KLDEFNDLYIVMELMDA-N
F09C12.2_Cele_MAPK-Unclassified    REIRITRELS------HENIINSTDVLMRES-----------G-SGQDIYIVMDLMET-D
C49C3.10_Cele_JNK                  RELNCMLNIE------DDNVVKMYSTFTPAE----------NPLKMTEFYIVREYMHG-T
C05D10.2_Cele_ERK7                 REVMFLQEFG-----KHPNVIKLYNIFRAD--------------NDRDIYLAFEFMEA-D
C04G6.1_Cele_MAPK-Unclassified     REVRILRELL------HENIIAVLDMFTAEG-----------A-HGKDIYLVMDLMET-D
SMK1_Scer_ERK1                     RELKFMNFFK-----GHKNIVNLIDLEIV-----------T-SSPYDGLYCYQELIDY-D
SLT2_Scer_ERK1                     RELKLLRHFR-----GHKNITCLYDMDIVF----------YPDGSINGLYLYEELMEC-D
KSS1_Scer_ERK1                     REIKLLRYFH-----EHENIISILDKVRP-----------VSIDKLNAVYLVEELMET-D
HOG1_Scer_p38                      RELKLLKHLR------HENLICLQDIFLS---------------PLEDIYFVTELQGT-D
FUS3_Scer_ERK1                     REIKILKHFK------HENIITIFNIQRP-----------DSFENFNEVYIIQELMQT-D
Erk4_Hsap_ERK3                     REIKIIRRLD------HDNIVKVYEVLGPKGTDLQ-----GELFKFSVAYIVQEYMET-D
Erk3_Hsap_ERK3                     REIKIIRRLD------HDNIVKVFEILGPSGSQLTD--DVGSLTELNSVYIVQEYMET-D
Erk2_Hsap_ERK1                     REIKILLRFR------HENIIGINDIIRA-----------PTIEQMKDVYIVQDLMET-D
Erk1_Hsap_ERK1                     REIQILLRFR------HENVIGIRDILRA-----------STLEAMRDVYIVQDLMET-D
T07A9.3_Cele_JNK                   REFILLTTIK------HPNIIRLLNAFTPDT----------SLSTFREVYLVMELMTH-N
W06B3.2_Cele_MAPK-Unclassified     REIRVLRYIN------HPNIVPLRDIFRTKG-----------PL-GIDVFLVMDLMQN-N
Y51B9A.9_Cele_JNK                  RELFCTLHIQ------EENFVKMYSIYTWVE----------TVEEMREFYTVREYMDW-N
ZC416.4_Cele_JNK                   REFILLTTLK------HPNIIRLLNAFTPDT----------SLSSFQEVYLVMEFMTH-N
YKL161C_Scer_ERK1                  RELKLLRHLR-----GHPNIVWLFDTDIVF----------YPNGALNGVYLYEELMEC-D
Erk1_Ddis_ERK                      REIHLLRHFK------HENLISIKDILKPNS-----------KEQFEDVYIVSELMDT-D
Erk2_Ddis_ERK7                     REIMFLQELH-----GHENIIKLLNVIKAD--------------NDRDIYLVFEHMET-D
13785_Tthe_ERK                     RQIKIENHFK------HENISSNLHIMM----------------ESKNLYIVREFIDT-D
18504_Tthe_ERK                     RELRLLRLLK------HENIIGINTLLLP-----------RSREKFEDIYVVSELMET-D
18512_Tthe_ERK                     RELKLLRLLT------HENVIGLESILLP-----------KSREEFDDIYCVSELMET-D
18725_Tthe_ERK                     REIKLLKFFE------HDNIISLLDVIKPNA-----------PVGDEDIYMVFDLMET-D
23186_Tthe_ERK                     REIKILKAL------EHDNIISIRDVLSP-----------VPKEKLEDIYIISQLMDT-D
4173_Tthe_ERK                      REIKLLKFCN------HPNIIKLKDIIKPEM-----------PTGYKDIYLVLEYMEI-D
6784_Tthe_ERK                      REIKMLKFFD------HENIIALHDIIVPEQ-----------RTDYNDIYIVTELMET-D
28107_Tthe_ERK                     REIKLQRMLA------HENLL------LP-----------KSREQMNDIYLVEPLMTS-D
27541_Tthe_ERK7                    REVMFLQELN-----GHENIVKLLNIIKAE--------------NNKDLYLVFDFMET-D
28942_Tthe_ERK7                    REVMFLQELN-----GHENIIRLINIIKAE--------------NNKDLYMVFDFMET-D
3210_Tthe_ERK7                     REIMFLQEL------DHENIIKVINVIRAK--------------NDRDIYVVFEYMDT-D
11145_Tthe_MAPK-Unclassified       RELYIQRHLS------HPNVMKIQNIYYNK-----------ELHNFDRIYIVMEYYPF-S
16370_Tthe_MAPK-Unclassified       REIHLLRILN------HPNLIRINEIIEPKD-----------LQNFDTLYVVTEYCQS-D
23757_Tthe_ERK                     REIRILRYL------VHENILQLSDILYDDE---------DENQEFGTIYLVTNYMEI-D
13784_Tthe_ERK                     ------------------------------------------------------------
17883_Tthe_ERK                     RSIKIENHFQ------HENINSNLHIMM----------------ESKNLYIVKELMDI-N
ERK5_Spur_ERK5                     RELKILRHFR------HENVIAIREILMPKE----------PLSEMKDVYVVFDLMES-D
ERK3_Spur_ERK3                     REIRILRKLQ------HENIVKIYDVIFDGNSDNSEDEDISIPSELRTLCIVQELVDA-D
ERK1_Spur_ERK1                     REIKILTRFN------HENIINIQDIIKA-----------DTIEAMRDVYIVQSLMET-D
ERK7_Spur_ERK7                     ------------------------------------------------------------
JNK_Spur_JNK                       REYILMKLCN------HKNIIGLLNVFTPQR----------TFDDFADIYLVMELMDA-S
NLK_Spur_nmo                       RELKMLFFFN------HDNSH-----FSGR-----------NCLESLHKYVVTELLQS-D
p38_Spur_p38                       RELRLLKHMR------HENVISLLDCFTPD-----------R-VNFSDVYMVTHLMGA-D
CC1G_02007_Ccin_ERK1               REIRLLHHFR-----GHKNITCLYDMDIVF----------QPNGNFDEVYLYEELMEA-D
CC1G_14865_Ccin_MAPK-Unclassified  REITLLRHFA-----NHENITGLIDVDAV-------------SPDFNEIYIFME------
CC1G_03633_Ccin_MAPK-Unclassified  RELKLLKFFSE--TCVNENIISILDIIKP-----------PSLEEFKEIYFIQELMQT-D
CC1G_07620_Ccin_MAPK-Unclassified  RELKLLKFLSE--AGVSENIISILDIIKP-----------PSLEAFKEVYLIQELMET-D
CC1G_00577_Ccin_MAPK-Unclassified  RELKLLKHIQ------HENIISLSDVFIS---------------PLEDLYFVTELLGT-D
AqueK118_Aque_ERK1                 REIKILTRFR------HENIIGILDILKP-----------PSMAEMKDVYIVQTLMET-D
AqueK119_Aque_ERK1                 RELQVISRLQKALG-DDLPIPELIDIVCEPAN--------QPIGEGTKFYVVQEAKEG-T
AqueK120_Aque_ERK1                 REIQILTRLQRMYSDDYDPFPRIIDFICYPQN--------LSGPKQAELYVVQTAFDV-N
AqueK121_Aque_ERK5                 RELKILRHLR------HENVISILDVMEPPE----------NESSLQDVYVILDLMET-D
AqueK122_Aque_ERK7                 -----------------------------------------------------------D
AqueK123_Aque_ERK7                 -------------------------------------------------------IET-D
AqueK124_Aque_ERK7                 ------------------------------------------------------------
AqueK125_Aque_ERK7                 ------------------------------------------------------------
AqueK126_Aque_ERK7                 REILFLQAFS-----NHPNVIQLINVIRSS--------------TDKDIYLVFEFMDT-D
AqueK127_Aque_JNK                  RELKLMKMVN------HKNVIGLLNLFSPAH----------SIEDFEDVYIVMELMDA-N
AqueK128_Aque_nmo                  REIKMLCELK------HDNILSAIDFIKPD-----------NMEEFSDIYVLTDLMET-D
AqueK129_Aque_p38                  RELRLLKHMK------HENIIGLLDVFTPAE----------NYENFQDVYLVMHLMGS-D
AqueK130_Aque_p38                  REIKLLKMLTR----SNANVVELLDVFTPND----------SLDSFNDIYLVTCFMQS-D
AqueK131_Aque_p38                  REMRILSHLK------HENCIGLLDVFSPCE----------DIEEFSDFYMVMHLMSM-D
ERK-p2-2_Smoe_ERK1                 REIKLLRHMD------HENIVAIRDIIRPPS-----------KDEFNDVYIVYELMDT-D
ERK-Un_Smoe_ERK1                   REVCIMRRLS------HRYVITLTDVFISMSM---------EVSGGIDLYIATEFADGGD
ERK5_b_Smoe_ERK1                   REIKLLRLLR------HPDVVEIKHILLPPS-----------RREFKDIYVVFELMES-D
ERK-p1_a-2_Smoe_ERK1               ------------------------------------------------------------
ERK5_a-2_Smoe_ERK1                 REIKLLRLLR------HPDIVEIKHIMLPPS-----------RREFKDIYVVFELMES-D
ERK-p1_b-1_Smoe_ERK1               REIRLLRHLY------HENIIGIKDIMKPVG-----------RSSFNDVYLVYELMDT-D
ERK7_Smoe_ERK1                     REVMFLQEIN-----DHENVIKLTNVLKAE--------------NDRDLYLVFEYMET-D
ERK5_a-1_Smoe_ERK1                 REIKLLRLLR------HPDIVEIKHIMLPPS-----------RREFKDIYVVFELMES-D
ERK5_c_Smoe_ERK1                   REIKLLRLLR------HPDVVEIKHILLPPS-----------RREFKDIYVVFELMES-D
ERK-p2-1_Smoe_ERK1                 REIKLLRHMD------HENIVAIRDIIRPPS-----------KDEFNDVYIVYELMDT-D
ERK-p1_a-1_Smoe_ERK1               REMRLLRYLQ------HENVVGLLDIMKPVG-----------RYTFNDVYLVYELMDT-D
ERK-p1_b-2_Smoe_ERK1               REIRLLRHLY------HENIIGIKDIMKPVG-----------RSSFNDVYLVYELMDT-D
GK037_Glam_ERK1                    REITILRMLD------HENIVKLLDVLVPED-----------PSNFDDLYVVFDFMQT-D
GK038_Glam_ERK7                    REIMFLQEL------DHDNIIRLFNVLKAE--------------NDKDIYLVFEFLDS-D


p38g_Hsap_p38                      LGKLMKH---------EKL--GEDRIQFLVYQMLKGLR----------Y-----------
p38d_Hsap_p38                      LQKIMGM----------EF--SEEKIQYLVYQMLKGLK----------Y-----------
p38b_Hsap_p38                      LNNIVKC---------QAL--SDEHVQFLVYQLLRGLK----------Y-----------
p38a_Hsap_p38                      LNNIVKC---------QKL--TDDHVQFLIYQILRGLK----------Y-----------
NLK_Hsap_nmo                       LHKIIVS---P-----QPL--SSDHVKVFLYQILRGLK----------Y-----------
JNK3_Hsap_JNK                      LCQVIQ-----M-----EL--DHERMSYLLYQMLCGIK----------H-----------
JNK2_Hsap_JNK                      LCQVIH-----M-----EL--DHERMSYLLYQMLCGIK----------H-----------
JNK1_Hsap_JNK                      LCQVIQ-----M-----EL--DHERMSYLLYQMLCGIK----------H-----------
Erk7_Hsap_ERK7                     LNAVIRK---G-----GLL--QDVHVRSIFYQLLRATR----------F-----------
Erk5_Hsap_ERK5                     LHQIIHS---S-----QPL--TLEHVRYFLYQLLRGLK----------Y-----------
nmo_Dmel_nmo                       LHKIIVS---P-----QHL--SADHIKVFLYQILRGLK----------Y-----------
CG2309_Dmel_ERK7                   LHNVIKR---G-----NVL--KDVHKRFVMYQLINAIK----------F-----------
P38c_Dmel_p38                      LHRYSRS---------KRM--SDQEIRIILYQILRGLK----------Y-----------
Mpk2_Dmel_p38                      LNNIIRM---------QHL--SDDHVQFLVYQILRGLK----------Y-----------
p38b_Dmel_p38                      LNNIIRT---------QKL--SDDHVQFLVYQILRGLK----------Y-----------
bsk_Dmel_JNK                       LCQVIQ-----M-----DL--DHDRMSYLLYQMLCGIK----------H-----------
rl_Dmel_ERK1                       LYKLLKT---------QRL--SNDHICYFLYQILRGLK----------Y-----------
p38g_Mmus_p38                      LGKLMKH---------ETL--SEDRIQFLVYQMLKGLK----------Y-----------
p38d_Mmus_p38                      LQKIMGM----------EF--SEDKVQYLVYQMLKGLK----------Y-----------
p38b_Mmus_p38                      LNNIVKC---------QAL--SDEHVQFLVYQLLRGLK----------Y-----------
p38a_Mmus_p38                      LNNIVKC---------QKL--TDDHVQFLIYQILRGLK----------Y-----------
NLK_Mmus_nmo                       LHKIIVS---P-----QPL--SSDHVKVFLYQILRGLK----------Y-----------
JNK3_Mmus_JNK                      LCQVIQ-----M-----EL--DHERMSYLLYQMLCGIK----------H-----------
JNK2_Mmus_JNK                      LCQVIH-----M-----EL--DHERMSYLLYQMLCGIK----------H-----------
JNK1_Mmus_JNK                      LCQVIQ-----M-----EL--DHERMSYLLYQMLCGIK----------H-----------
ERK7_Mmus_ERK7                     LNAVIQK---G-----RLL--KDIHKRCIFYQLLRATK----------F-----------
ERK5_Mmus_ERK5                     LHQIIHS---S-----QPL--TLEHVRYFLYQLLRGLK----------Y-----------
ERK4_Mmus_ERK3                     LACLLEQ---------GTL--TEDHAKLFMYQLLRGLK----------Y-----------
ERK3_Mmus_ERK3                     LANVLEQ---------GPL--LEEHARLFMYQLLRGLK----------Y-----------
ERK2_Mmus_ERK1                     LYKLLKT---------QHL--SNDHICYFLYQILRGLK----------Y-----------
ERK1_Mmus_ERK1                     LYKLLKS---------QQL--SNDHICYFLYQILRGLK----------Y-----------
pmk-3_Cele_p38                     LYQILKQ---QRDYGRRVL--TDEHIKFIIYQIIRALK----------Y-----------
pmk-2_Cele_p38                     LQNIMKI---------QRL--TDEQIQLLIYQVLRGLK----------YMSHQNFNSTII
pmk-1_Cele_p38                     LSNILKI---------QRL--NDDHIQFLVYQILRGLK----------Y-----------
mpk-1_Cele_ERK1                    LYKLLKT---------QKL--SNDHVCYFLYQILRGLK----------Y-----------
lit-1_Cele_nmo                     LHKIIVS---P-----QAL--TPDHVKVFVYQILRGLK----------Y-----------
jnk-1_Cele_JNK                     LCQVIQ-----M-----DL--DHERLSYLLYQMLCGIR----------H-----------
F09C12.2_Cele_MAPK-Unclassified    LLSVLKS---N-----QTL--NEKHFQYFFYQILKGLK----------Y-----------
C49C3.10_Cele_JNK                  MKNLSAS---TF----NEG--GHRTVKSIFFDICRGVQ----------Y-----------
C05D10.2_Cele_ERK7                 LHNVIKK---G-----SIL--KDVHKQYIMCQLFRAIR----------F-----------
C04G6.1_Cele_MAPK-Unclassified     LHQILHS---R-----QTL--MEQHFQYFFYQLLRGLK----------Y-----------
SMK1_Scer_ERK1                     LAKVIHS---S-----VQL--SEFHIKYFLYQILCGLK----------Y-----------
SLT2_Scer_ERK1                     MHQIIKS---G-----QPL--TDAHYQSFTYQILCGLK----------Y-----------
KSS1_Scer_ERK1                     LQKVINN---QNS-GFSTL--SDDHVQYFTYQILRALK----------S-----------
HOG1_Scer_p38                      LHRLLQT---------RPL--EKQFVQYFLYQILRGLK----------Y-----------
FUS3_Scer_ERK1                     LHRVIST---Q------ML--SDDHIQYFIYQTLRAVK----------V-----------
Erk4_Hsap_ERK3                     LARLLEQ---------GTL--AEEHAKLFMYQLLRGLK----------Y-----------
Erk3_Hsap_ERK3                     LANVLEQ---------GPL--LEEHARLFMYQLLRGLK----------Y-----------
Erk2_Hsap_ERK1                     LYKLLKT---------QHL--SNDHICYFLYQILRGLK----------Y-----------
Erk1_Hsap_ERK1                     LYKLLKS---------QQL--SNDHICYFLYQILRGLK----------Y-----------
T07A9.3_Cele_JNK                   LHEVIH-----R----LRL--DHKTLSFFVYQSLCAIK----------H-----------
W06B3.2_Cele_MAPK-Unclassified     LHHIIYG---NE----DPL--EEHYINAFLGQLLRGLE----------Y-----------
Y51B9A.9_Cele_JNK                  LRNFILS---TP----EKL--DHKVIKSIFFDVCLAVQ----------Y-----------
ZC416.4_Cele_JNK                   LHEVIH-----R----LRL--DHETLSFLVYQSLCAIK----------H-----------
YKL161C_Scer_ERK1                  LSQIIRS---E-----QRL--EDAHFQSFIYQILCALK----------Y-----------
Erk1_Ddis_ERK                      LHQIITS---P-----QPL--SDDHCQYFVYQMLRGLK----------H-----------
Erk2_Ddis_ERK7                     LHAVIRA---------KIL--EEIHKQYTIYQLLKALK----------Y-----------
13785_Tthe_ERK                     LHRVNFS---K-----QEL--TDDHIQYFTYQILSALF----------F-----------
18504_Tthe_ERK                     LASIIKS---E-----QPL--TDEHCQFFLYQILRGLK----------Y-----------
18512_Tthe_ERK                     LQQIIKS---D-----QQL--TQDHCKFFIYQILRGLK----------Y-----------
18725_Tthe_ERK                     LHRVIYS---R-----QEL--SDEHIQYFVYQILRGLL----------Y-----------
23186_Tthe_ERK                     LHQIIAS---D-----QIL--SEDHIQFFIYQLLCGLKYVNQIYYFLKY-----------
4173_Tthe_ERK                      LDKTINS---E-----QAL--SPKIIKNLMWQLLNGIF----------Y-----------
6784_Tthe_ERK                      LHRVIYS---R-----QEL--TDDHIQYFLYQTLRGML----------Y-----------
28107_Tthe_ERK                     LRAIINS---Q-----NEI--NEEHIQFLMYQIIRGLK----------Y-----------
27541_Tthe_ERK7                    LHAVIRA---------DIL--EEIHKKYVMYQILKALK----------Y-----------
28942_Tthe_ERK7                    LHAVIRA---------NIL--EEIHKQYVVYQILKAMK----------Y-----------
3210_Tthe_ERK7                     LHAVIRV---------NIL--EDIHKQYIMYQIFRAIK----------Y-----------
11145_Tthe_MAPK-Unclassified       LFDILYQ---YQ----QNLTWSHELVRIIFTQIVNGLA----------Y-----------
16370_Tthe_MAPK-Unclassified       LKKLFKS---P-----IHL--CMIQVQTLTYNILTGIK----------Y-----------
23757_Tthe_ERK                     LYQVIKS---D-----QKL--SDQHIQYIIYQILKGLK----------Y-----------
13784_Tthe_ERK                     ------------------------------------------------------------
17883_Tthe_ERK                     LKDVTFS---R-----QEL--TDEHIKWFVYQILKALN----------F-----------
ERK5_Spur_ERK5                     LHQIIHS---N-----QPF--SLEHIRFFLYQILRGLK----------Y-----------
ERK3_Spur_ERK3                     LRVVMEQ---------QRI--SNEHVRLFAYQLLRGLK----------Y-----------
ERK1_Spur_ERK1                     LYKLLKT---------QPL--SNDHICYFLYQILRGLK----------Y-----------
ERK7_Spur_ERK7                     ------------------------------------------------------------
JNK_Spur_JNK                       LVQVVQ-----M-----DL--DHERISYLLYQMLCGIK----------H-----------
NLK_Spur_nmo                       LHKIIVS---P-----QPL--SSDHVKVFLYQILRGLK----------Y-----------
p38_Spur_p38                       LNNIIKC---------QKL--SDDHVQFLIYQVLRGLK----------Y-----------
CC1G_02007_Ccin_ERK1               LHAIIRS---G-----QPL--TDAHFQSFIYQTLCGLK----------Y-----------
CC1G_14865_Ccin_MAPK-Unclassified  ------S---G-----QVL--TNEHVQYFLYQILRGMK----------F-----------
CC1G_03633_Ccin_MAPK-Unclassified  LHRVIRT---Q------HL--TDDHCQYFVYQTLRALK----------S-----------
CC1G_07620_Ccin_MAPK-Unclassified  MHRVIRT---Q------DL--SDDHAQYFIYQTLRALK----------A-----------
CC1G_00577_Ccin_MAPK-Unclassified  LHRLLTS---------RPL--EKQFIQYFLYQILRGLK----------Y-----------
AqueK118_Aque_ERK1                 LYKLLKT---------QHL--SNDHICYFLYQILRGLK----------Y-----------
AqueK119_Aque_ERK1                 IEIILQA---D-----QLP--SPEQVKILMYQLLRALK----------L-----------
AqueK120_Aque_ERK1                 LADILNQ---Q------RM--THDQIWCIMYSLLVSLK----------L-----------
AqueK121_Aque_ERK5                 LHHIIHS---V-----QPL--SDDHIKYFLYQIGRGLK----------Y-----------
AqueK122_Aque_ERK7                 LHAVIKS---K-----IPV--LSVHMQYIMSQLCRVLK----------Y-----------
AqueK123_Aque_ERK7                 LHAVIKS---------K-I--LSVHMQYIMSQLCRVLK----------Y-----------
AqueK124_Aque_ERK7                 ------------------------------------------------------------
AqueK125_Aque_ERK7                 ------------------------------------------------------------
AqueK126_Aque_ERK7                 LHAVIKS---------KIL--QSVHMQYIMSQLCRVLK----------Y-----------
AqueK127_Aque_JNK                  LCRVIG-----I-----EL--DHDRMSYLLYQLLCGIK----------H-----------
AqueK128_Aque_nmo                  LHHIIIS---P-----QPL--TEDHIKLFLYQLLRGVK----------Y-----------
AqueK129_Aque_p38                  INNILKQ---------QAL--TDEHVQFLVYQILRGLK----------Y-----------
AqueK130_Aque_p38                  LDNAIKI---------QPI--TDDQVQLLVYQILRGLK----------Y-----------
AqueK131_Aque_p38                  LAKLLKENRTS-----QIL--SEDHIKFLLYQILCGLK----------Y-----------
ERK-p2-2_Smoe_ERK1                 LHQIIRS---N-----QQL--TDDHCQYFLYQLLRGLK----------Y-----------
ERK-Un_Smoe_ERK1                   MYH-LR----E------PL--TPEHVKFLMWQLLTGMS----------Y-----------
ERK5_b_Smoe_ERK1                   LHQVIKA---N-----DDL--MPEHYQFFLYQLLRGLK----------F-----------
ERK-p1_a-2_Smoe_ERK1               ----------------------------------RGLK----------Y-----------
ERK5_a-2_Smoe_ERK1                 LHQVIKA---N-----DDL--TPEHYQFFLYQLLRALK----------Y-----------
ERK-p1_b-1_Smoe_ERK1               LHQIIRS---S-----QAL--TDDHCQYFIYQLLRGLK----------Y-----------
ERK7_Smoe_ERK1                     LHAVIRA---------NIL--EDVHKQYIMYQLFKSLK----------Y-----------
ERK5_a-1_Smoe_ERK1                 LHQVIKA---N-----DDL--TPEHYQFFLYQLLRALK----------Y-----------
ERK5_c_Smoe_ERK1                   LHQVIKA---N-----DDL--MPEHYQFFLYQLLRGLK----------F-----------
ERK-p2-1_Smoe_ERK1                 LHQIIRS---N-----QQL--TDDHCQYFLYQLLRGLK----------Y-----------
ERK-p1_a-1_Smoe_ERK1               LHQIIRS---S-----QPL--TDEHYQFFIYQLLRGLK----------Y-----------
ERK-p1_b-2_Smoe_ERK1               LHQIIRS---S-----QAL--TDDHCQYFIYQLLRGLK----------Y-----------
GK037_Glam_ERK1                    MHKIISS---K-----QDL--SPDHMQYFVYQLLRGLK----------Y-----------
GK038_Glam_ERK7                    LHQVIKS---------NIL--EDIHKRYIIYQCVKALK----------Y-----------


p38g_Hsap_p38                      ------------------IHAAGIIHRDLKPGNLAVNE-DCEL-----------------
p38d_Hsap_p38                      ------------------IHSAGVVHRDLKPGNLAVNE-DCEL-----------------
p38b_Hsap_p38                      ------------------IHSAGIIHRDLKPSNVAVNE-DCEL-----------------
p38a_Hsap_p38                      ------------------IHSADIIHRDLKPSNLAVNE-DCEL-----------------
NLK_Hsap_nmo                       ------------------LHSAGILHRDIKPGNLLVNS-NCVL-----------------
JNK3_Hsap_JNK                      ------------------LHSAGIIHRDLKPSNIVVKS-DCTL-----------------
JNK2_Hsap_JNK                      ------------------LHSAGIIHRDLKPSNIVVKS-DCTL-----------------
JNK1_Hsap_JNK                      ------------------LHSAGIIHRDLKPSNIVVKS-DCTL-----------------
Erk7_Hsap_ERK7                     ------------------LHSGHVVHRDQKPSNVLLDA-NCTV-----------------
Erk5_Hsap_ERK5                     ------------------MHSAQVIHRDLKPSNLLVNE-NCEL-----------------
nmo_Dmel_nmo                       ------------------LHSARILHRDIKPGNLLVNS-NCVL-----------------
CG2309_Dmel_ERK7                   ------------------IHSGNVIHRDLKPSNILIDS-KCRL-----------------
P38c_Dmel_p38                      ------------------IHSAGVVHRDLKPCNIAVNG-NSEV-----------------
Mpk2_Dmel_p38                      ------------------IHSAGVIHRDLKPSNIAVNE-DCEL-----------------
p38b_Dmel_p38                      ------------------IHSAGVIHRDLKPSNIAVNE-DCEL-----------------
bsk_Dmel_JNK                       ------------------LHSAGIIHRDLKPSNIVVKA-DCTL-----------------
rl_Dmel_ERK1                       ------------------IHSANVLHRDLKPSNLLLNK-TCDL-----------------
p38g_Mmus_p38                      ------------------IHAAGVIHRDLKPGNLAVNE-DCEL-----------------
p38d_Mmus_p38                      ------------------IHSAGIVHRDLKPGNLAVNE-DCEL-----------------
p38b_Mmus_p38                      ------------------IHSAGIIHRDLKPSNVAVNE-DCEL-----------------
p38a_Mmus_p38                      ------------------IHSADIIHRDLKPSNLAVNE-DCEL-----------------
NLK_Mmus_nmo                       ------------------LHSAGILHRDIKPGNLLVNS-NCVL-----------------
JNK3_Mmus_JNK                      ------------------LHSAGIIHRDLKPSNIVVKS-DCTL-----------------
JNK2_Mmus_JNK                      ------------------LHSAGIIHRDLKPSNIVVKS-DCTL-----------------
JNK1_Mmus_JNK                      ------------------LHSAGIIHRDLKPSNIVVKS-DCTL-----------------
ERK7_Mmus_ERK7                     ------------------IHSGRVIHRDQKPANVLLDS-ACRV-----------------
ERK5_Mmus_ERK5                     ------------------MHSAQVIHRDLKPSNLLVNE-NCEL-----------------
ERK4_Mmus_ERK3                     ------------------IHSANVLHRDLKPANIFISTEDLVL-----------------
ERK3_Mmus_ERK3                     ------------------IHSANVLHRDLKPANLFINTEDLVL-----------------
ERK2_Mmus_ERK1                     ------------------IHSANVLHRDLKPSNLLLNT-TCDL-----------------
ERK1_Mmus_ERK1                     ------------------IHSANVLHRDLKPSNLLINT-TCDL-----------------
pmk-3_Cele_p38                     ------------------IHSANIIHRDLKPGNLALTD-DSDL-----------------
pmk-2_Cele_p38                     LKKLMHPFQRRNTRFRLYIHSAGIIHRDLKPSNIAVNE-RCEVKVFLSFSQLSFLILSFF
pmk-1_Cele_p38                     ------------------IHSADIIHRDLKPSNIAVNE-DCEL-----------------
mpk-1_Cele_ERK1                    ------------------IHSANVLHRDLKPSNLLLNT-TCDL-----------------
lit-1_Cele_nmo                     ------------------LHTANILHRDIKPGNLLVNS-NCIL-----------------
jnk-1_Cele_JNK                     ------------------LHSAGIIHRDLKPSNIVVRS-DCTL-----------------
F09C12.2_Cele_MAPK-Unclassified    ------------------LHSAGIIHRDLKPANLLLNE-DCSL-----------------
C49C3.10_Cele_JNK                  ------------------LHAMRISHRDLKPENILMNQ-EGDV-----------------
C05D10.2_Cele_ERK7                 ------------------LHSGNVLHRDLKPSNVLLDA-DCRV-----------------
C04G6.1_Cele_MAPK-Unclassified     ------------------LHSAGIIHRDLKPSNLLLNG-DCLL-----------------
SMK1_Scer_ERK1                     ------------------IHSADVIHRDLKPGNILCTL-NGCL-----------------
SLT2_Scer_ERK1                     ------------------IHSADVLHRDLKPGNLLVNA-DCQL-----------------
KSS1_Scer_ERK1                     ------------------IHSAQVIHRDIKPSNLLLNS-NCDL-----------------
HOG1_Scer_p38                      ------------------VHSAGVIHRDLKPSNILINE-NCDL-----------------
FUS3_Scer_ERK1                     ------------------LHGSNVIHRDLKPSNLLINS-NCDL-----------------
Erk4_Hsap_ERK3                     ------------------IHSANVLHRDLKPANIFISTEDLVL-----------------
Erk3_Hsap_ERK3                     ------------------IHSANVLHRDLKPANLFINTEDLVL-----------------
Erk2_Hsap_ERK1                     ------------------IHSANVLHRDLKPSNLLLNT-TCDL-----------------
Erk1_Hsap_ERK1                     ------------------IHSANVLHRDLKPSNLLINT-TCDL-----------------
T07A9.3_Cele_JNK                   ------------------LHNSGVIHRDLKPSNIVVND-RCVL-----------------
W06B3.2_Cele_MAPK-Unclassified     ------------------LHAACIAHRDLKPSNLLVNQ-DGTL-----------------
Y51B9A.9_Cele_JNK                  ------------------MHSIRVGHRDLKPENVLINY-EAIA-----------------
ZC416.4_Cele_JNK                   ------------------LHNLGFIHRDLKPSNIVVNE-RCVL-----------------
YKL161C_Scer_ERK1                  ------------------IHSANVLHCDLKPKNLLVNS-DCQL-----------------
Erk1_Ddis_ERK                      ------------------IHSANVLHRDLKPSNLLINE-DCLL-----------------
Erk2_Ddis_ERK7                     ------------------MHSANVLHRDIKPSNLLLNS-ECLV-----------------
13785_Tthe_ERK                     ------------------LHSQNVYHTQLRLSNILLNK-NCDL-----------------
18504_Tthe_ERK                     ------------------IHSAKVVHRDLKPRNLLVNS-NCDL-----------------
18512_Tthe_ERK                     ------------------IHSANVIHRDLKPRNLLVNS-NCDL-----------------
18725_Tthe_ERK                     ------------------IHSANVIHRDLKPSNILLNK-NCDL-----------------
23186_Tthe_ERK                     ------------------IHSAGVFHRDLKPGNLLVNS-DCVL-----------------
4173_Tthe_ERK                      ------------------MHSADIIHRDIKPSNILLNK-NCTL-----------------
6784_Tthe_ERK                      ------------------IHSANVMHRDLKPSNILVNK-NCDL-----------------
28107_Tthe_ERK                     ------------------MHSAQIVHRDLKPKNVLSNE-QGDL-----------------
27541_Tthe_ERK7                    ------------------MHSGDLIHRDLKPSNILLNS-ECHV-----------------
28942_Tthe_ERK7                    ------------------IHSGELIHRDLKPSNILLNS-ECLV-----------------
3210_Tthe_ERK7                     ------------------IHSGELIHRDLKASNILVNS-DCMV-----------------
11145_Tthe_MAPK-Unclassified       ------------------IHSRNIIHRDLKPSNILIDQ-NLNV-----------------
16370_Tthe_MAPK-Unclassified       ------------------LHSAEVLHRDLKPANVLINE-DCSV-----------------
23757_Tthe_ERK                     ------------------LHSANIIHRDLKPSNLLATE-KCAI-----------------
13784_Tthe_ERK                     ---------------------------------ILLNQ-NCEL-----------------
17883_Tthe_ERK                     ------------------LHSQNVYHTELTARDILLKE-NCDL-----------------
ERK5_Spur_ERK5                     ------------------IHSADVIHRDLKPSNLLVNE-NCEL-----------------
ERK3_Spur_ERK3                     ------------------LHSANVLHRDLKPENVLINQEDLVL-----------------
ERK1_Spur_ERK1                     ------------------IHSANVLHRDLKPSNLLLNT-TCDL-----------------
ERK7_Spur_ERK7                     ------------------------------PSNILLDT-ECFV-----------------
JNK_Spur_JNK                       ------------------LHSAGIIHRDLKPSNIVVKT-DCSL-----------------
NLK_Spur_nmo                       ------------------LHSAGILHRDI-------------------------------
p38_Spur_p38                       ------------------IHSAGVIHRDLKPSNIAVNE-DCEL-----------------
CC1G_02007_Ccin_ERK1               ------------------IHSANVLHRDLKPGNLLVNA-DCEL-----------------
CC1G_14865_Ccin_MAPK-Unclassified  ------------------IHSAGVIHRDLKPGNLLVNA-DCEL-----------------
CC1G_03633_Ccin_MAPK-Unclassified  ------------------IHSADIVHRDLKPANLLLNA-NCDL-----------------
CC1G_07620_Ccin_MAPK-Unclassified  ------------------LHSADVIHRDLKPSNLLLNA-NCDL-----------------
CC1G_00577_Ccin_MAPK-Unclassified  ------------------VHSAGVVHRDLKPSNILVNE-NCDL-----------------
AqueK118_Aque_ERK1                 ------------------IHSANVLHRDLKPSNLLLNT-TCDL-----------------
AqueK119_Aque_ERK1                 ------------------FHSAGIIHRCIRSNDILIDA-DCDL-----------------
AqueK120_Aque_ERK1                 ------------------LHSAGVVHRCIRPRHLLLTS-EFDL-----------------
AqueK121_Aque_ERK5                 ------------------IHSANIIHRDLKPSNLLINR-NCEL-----------------
AqueK122_Aque_ERK7                 ------------------IHSGNVIHRDLKPSNILINS-ECFI-----------------
AqueK123_Aque_ERK7                 ------------------IHSGNVIHRDLKPSNILINS-ECFI-----------------
AqueK124_Aque_ERK7                 ------------------------------------------------------------
AqueK125_Aque_ERK7                 ------------------------------------------------------------
AqueK126_Aque_ERK7                 ------------------IHSGNVIHRDLKPSNILINS-ECFI-----------------
AqueK127_Aque_JNK                  ------------------LHSAGIIHRDLKPSNIVVKE-DCSL-----------------
AqueK128_Aque_nmo                  ------------------LHSAGIIHRDLKPGNLLVNS-TCLL-----------------
AqueK129_Aque_p38                  ------------------VHSAGIVHRDLKPSNIAVNE-DCEL-----------------
AqueK130_Aque_p38                  ------------------IHSAGVIHRDIKPSNIGVSS-DLEI-----------------
AqueK131_Aque_p38                  ------------------VHSAGIIHRDLKPSNIAVNP-TCDL-----------------
ERK-p2-2_Smoe_ERK1                 ------------------VHSANVLHRDLKPSNLLLNA-NCDL-----------------
ERK-Un_Smoe_ERK1                   ------------------IHSCRVWHRDLKSENILLMA-DMSV-----------------
ERK5_b_Smoe_ERK1                   ------------------IHTANVFHRDLKPKNVLANA-NCKL-----------------
ERK-p1_a-2_Smoe_ERK1               ------------------IHSANVLHRDLKPGNLLLNA-NCDL-----------------
ERK5_a-2_Smoe_ERK1                 ------------------IHTANVFHRDLKPKNILANA-DCKL-----------------
ERK-p1_b-1_Smoe_ERK1               ------------------VHSANVLHRDLKPSNLLLNA-SCDL-----------------
ERK7_Smoe_ERK1                     ------------------LHSAGLLHRDIKPSNLLLDS-DCRC-----------------
ERK5_a-1_Smoe_ERK1                 ------------------IHTANVFHRDLKPKNILANA-DCKL-----------------
ERK5_c_Smoe_ERK1                   ------------------IHTANVFHRDLKPKNVLANA-NCKL-----------------
ERK-p2-1_Smoe_ERK1                 ------------------VHSANVLHRDLKPSNLLLNA-NCDL-----------------
ERK-p1_a-1_Smoe_ERK1               ------------------IHSANVLHRDLKPGNLLLNA-NCDL-----------------
ERK-p1_b-2_Smoe_ERK1               ------------------VHSANVLHRDLKPSNLLLNA-SCDL-----------------
GK037_Glam_ERK1                    ------------------LHSANCVHRDLKPSNLLLNS-DCAL-----------------
GK038_Glam_ERK7                    ------------------LHSAEILHRDLKPSNLLLNS-ECHM-----------------


p38g_Hsap_p38                      KILDFGLARQADS-----------------------------------------------
p38d_Hsap_p38                      KILDFGLARHADA-----------------------------------------------
p38b_Hsap_p38                      RILDFGLARQADE-----------------------------------------------
p38a_Hsap_p38                      KILDFGLARHTDD-----------------------------------------------
NLK_Hsap_nmo                       KICDFGLARVEELD----------------------------------------------
JNK3_Hsap_JNK                      KILDFGLARTAGT-----------------------------------------------
JNK2_Hsap_JNK                      KILDFGLARTACT-----------------------------------------------
JNK1_Hsap_JNK                      KILDFGLARTAGT-----------------------------------------------
Erk7_Hsap_ERK7                     KLCDFGLARSLGDLP---------------------------------------------
Erk5_Hsap_ERK5                     KIGDFGMARGLCTSPA--------------------------------------------
nmo_Dmel_nmo                       KICDFGLARVEEPD----------------------------------------------
CG2309_Dmel_ERK7                   KVADFGLARTLSSRRIYD------------------------------------------
P38c_Dmel_p38                      RILDFGLSRMCAD-----------------------------------------------
Mpk2_Dmel_p38                      RILDFGLARPTEN-----------------------------------------------
p38b_Dmel_p38                      RILDFGLARPAES-----------------------------------------------
bsk_Dmel_JNK                       KILDFGLARTAGT-----------------------------------------------
rl_Dmel_ERK1                       KICDFGLARIADPE----------------------------------------------
p38g_Mmus_p38                      KILDFGLARQADS-----------------------------------------------
p38d_Mmus_p38                      KILDFGLARHTDT-----------------------------------------------
p38b_Mmus_p38                      RILDFGLARQADE-----------------------------------------------
p38a_Mmus_p38                      KILDFGLARHTDD-----------------------------------------------
NLK_Mmus_nmo                       KICDFGLARVEELD----------------------------------------------
JNK3_Mmus_JNK                      KILDFGLARTAGT-----------------------------------------------
JNK2_Mmus_JNK                      KILDFGLARTACT-----------------------------------------------
JNK1_Mmus_JNK                      KILDFGLARTAGT-----------------------------------------------
ERK7_Mmus_ERK7                     KLCDFGLARSLGDLP---------------------------------------------
ERK5_Mmus_ERK5                     KIGDFGMARGLCTSPA--------------------------------------------
ERK4_Mmus_ERK3                     KIGDFGLARIVDQHY---------------------------------------------
ERK3_Mmus_ERK3                     KIGDFGLARIMDPHY---------------------------------------------
ERK2_Mmus_ERK1                     KICDFGLARVADPD----------------------------------------------
ERK1_Mmus_ERK1                     KICDFGLARIADPE----------------------------------------------
pmk-3_Cele_p38                     MILDFGLARSLEKKD---------------------------------------------
pmk-2_Cele_p38                     KILDFGLARAQDA-----------------------------------------------
pmk-1_Cele_p38                     KILDFGLARQTDS-----------------------------------------------
mpk-1_Cele_ERK1                    KICDFGLARVTDPQ----------------------------------------------
lit-1_Cele_nmo                     KICDFGLARTWDQR----------------------------------------------
jnk-1_Cele_JNK                     KILDFGLARTAIE-----------------------------------------------
F09C12.2_Cele_MAPK-Unclassified    KIADFGMSRSGPSTKTTPN-----------------------------------------
C49C3.10_Cele_JNK                  KLCDFGHSNKEDP-----------------------------------------------
C05D10.2_Cele_ERK7                 KLADFGLARSLSSLEDYP------------------------------------------
C04G6.1_Cele_MAPK-Unclassified     RIADFGMARAYASASTVR------------------------------------------
SMK1_Scer_ERK1                     KICDFGLARGIHAGFFK-------------------------------------------
SLT2_Scer_ERK1                     KICDFGLARGYSENP---------------------------------------------
KSS1_Scer_ERK1                     KVCDFGLARCLASSSDS-------------------------------------------
HOG1_Scer_p38                      KICDFGLARIQDP-----------------------------------------------
FUS3_Scer_ERK1                     KVCDFGLARIIDESAADN------------------------------------------
Erk4_Hsap_ERK3                     KIGDFGLARIVDQHY---------------------------------------------
Erk3_Hsap_ERK3                     KIGDFGLARIMDPHY---------------------------------------------
Erk2_Hsap_ERK1                     KICDFGLARVADPD----------------------------------------------
Erk1_Hsap_ERK1                     KICDFGLARIADPE----------------------------------------------
T07A9.3_Cele_JNK                   KVLDFGLARKKNVDT---------------------------------------------
W06B3.2_Cele_MAPK-Unclassified     RIADFGMAKCADNSSKKH------------------------------------------
Y51B9A.9_Cele_JNK                  KISGFAHANREDP-----------------------------------------------
ZC416.4_Cele_JNK                   KVLDFGLARRRNV-----------------------------------------------
YKL161C_Scer_ERK1                  KICNFGLSCSYSENH---------------------------------------------
Erk1_Ddis_ERK                      KICDLGLARVEDAT----------------------------------------------
Erk2_Ddis_ERK7                     KVADFGLARSITSLE-S-------------------------------------------
13785_Tthe_ERK                     KISRFIGTNFPNE-----------------------------------------------
18504_Tthe_ERK                     KICDFGLARTIIPGL---------------------------------------------
18512_Tthe_ERK                     KICDFGLARSVAN-----------------------------------------------
18725_Tthe_ERK                     KICDFGLARGFEE-P---------------------------------------------
23186_Tthe_ERK                     KICDFGLARTVDTKV---------------------------------------------
4173_Tthe_ERK                      KLADMNLARKFDVEQSSIT--------E--------------------------------
6784_Tthe_ERK                      KVCDLGLARGFEFDE---------------------------------------------
28107_Tthe_ERK                     KICDFGFARHIQKN----------------------------------------------
27541_Tthe_ERK7                    KLADFGLARSVAQKE---------------------------------------------
28942_Tthe_ERK7                    KLADFGLARSVAVTD---------------------------------------------
3210_Tthe_ERK7                     KVADFGLVRSIANQE---------------------------------------------
11145_Tthe_MAPK-Unclassified       KIADFTLSRQNTTANFQNN---------QS------------------------------
16370_Tthe_MAPK-Unclassified       KICDFGLARSVEGNQNLR------------------------------------------
23757_Tthe_ERK                     RMCDFGLSRSIEDEQKQE---------QQLVRNLILFFSFIILMHNLHKQTNKQINKKTN
13784_Tthe_ERK                     KISDFLGAKFPND-----------------------------------------------
17883_Tthe_ERK                     KITGFIHSNFPH------------------------------------------------
ERK5_Spur_ERK5                     KVGDFGMARGLSTFST--------------------------------------------
ERK3_Spur_ERK3                     KIGDFGMARIVDPDY---------------------------------------------
ERK1_Spur_ERK1                     KICDFGLARIADPG----------------------------------------------
ERK7_Spur_ERK7                     KVADFGLARSITQIDAV-------------------------------------------
JNK_Spur_JNK                       KILDFGLARTAST-----------------------------------------------
NLK_Spur_nmo                       -VCDFGLARVEEPD----------------------------------------------
p38_Spur_p38                       RILDFGLARSTDD-----------------------------------------------
CC1G_02007_Ccin_ERK1               KICDFGLARGYTPGSGTS------------------------------------------
CC1G_14865_Ccin_MAPK-Unclassified  KICDFGLSRGFDAVP---------------------------------------------
CC1G_03633_Ccin_MAPK-Unclassified  KVCDFGLARSVKTSVP--------------------------------------------
CC1G_07620_Ccin_MAPK-Unclassified  KVCDFGLARSVKTAEP--------------------------------------------
CC1G_00577_Ccin_MAPK-Unclassified  KICDFGLARIQDP-----------------------------------------------
AqueK118_Aque_ERK1                 KICDFGLARIADPE----------------------------------------------
AqueK119_Aque_ERK1                 RVCDFRLAAVNGIESDP-------------------------------------------
AqueK120_Aque_ERK1                 AICDLRRSIM--NHEP--------------------------------------------
AqueK121_Aque_ERK5                 KIGDFGMARGLSSTPE--------------------------------------------
AqueK122_Aque_ERK7                 K-----------------------------------------------------------
AqueK123_Aque_ERK7                 Kxxxxxxxxxxxxxxxxx------------------------------------------
AqueK124_Aque_ERK7                 KLADFGLAHSLASTSNEG---------SKGV-----------------------------
AqueK125_Aque_ERK7                 -LADFGLAHSLASTSNEG---------SKGV-----------------------------
AqueK126_Aque_ERK7                 KLADFGLARSLASISNEG---------SKGA-----------------------------
AqueK127_Aque_JNK                  KILDFGLARAADK-----------------------------------------------
AqueK128_Aque_nmo                  RICDFGFARAVEVN----------------------------------------------
AqueK129_Aque_p38                  RILDFGLARATDQ-----------------------------------------------
AqueK130_Aque_p38                  KILDFGLGRKKKG-----------------------------------------------
AqueK131_Aque_p38                  RILDFGLARQTDR-----------------------------------------------
ERK-p2-2_Smoe_ERK1                 KICDFGLARTTSE-----------------------------------------------
ERK-Un_Smoe_ERK1                   KICDFGLSRSA-------------------------------------------------
ERK5_b_Smoe_ERK1                   KICDFGLARVAFNDAPT-------------------------------------------
ERK-p1_a-2_Smoe_ERK1               KIADFGLARTGREK----------------------------------------------
ERK5_a-2_Smoe_ERK1                 KICDFGLARVAFNDAPTAIFWTVSASNK--------------------------------
ERK-p1_b-1_Smoe_ERK1               KICDFGLARTGSDK----------------------------------------------
ERK7_Smoe_ERK1                     KLADFGLARSVAQLK-D-------------------------------------------
ERK5_a-1_Smoe_ERK1                 KICDFGLARVAFNDAPTAIFWTVSVSNK--------------------------------
ERK5_c_Smoe_ERK1                   KICDFGLARVAFNDAPT-------------------------------------------
ERK-p2-1_Smoe_ERK1                 KICDFGLARTTSE-----------------------------------------------
ERK-p1_a-1_Smoe_ERK1               KIADFGLARTGREK----------------------------------------------
ERK-p1_b-2_Smoe_ERK1               KICDFGLARTGSDK----------------------------------------------
GK037_Glam_ERK1                    EICDLGLARLVDDHAAKTKEL------K--------------------------------
GK038_Glam_ERK7                    KMADFGLARSIAALSEP-------------------------------------------


p38g_Hsap_p38                      ------------------------------------------------------------
p38d_Hsap_p38                      ------------------------------------------------------------
p38b_Hsap_p38                      ------------------------------------------------------------
p38a_Hsap_p38                      ------------------------------------------------------------
NLK_Hsap_nmo                       ------------------------------------------------------------
JNK3_Hsap_JNK                      ------------------------------------------------------------
JNK2_Hsap_JNK                      ------------------------------------------------------------
JNK1_Hsap_JNK                      ------------------------------------------------------------
Erk7_Hsap_ERK7                     ------------------------------------------------------------
Erk5_Hsap_ERK5                     ------------------------------------------------------------
nmo_Dmel_nmo                       ------------------------------------------------------------
CG2309_Dmel_ERK7                   ------------------------------------------------------------
P38c_Dmel_p38                      ------------------------------------------------------------
Mpk2_Dmel_p38                      ------------------------------------------------------------
p38b_Dmel_p38                      ------------------------------------------------------------
bsk_Dmel_JNK                       ------------------------------------------------------------
rl_Dmel_ERK1                       ------------------------------------------------------------
p38g_Mmus_p38                      ------------------------------------------------------------
p38d_Mmus_p38                      ------------------------------------------------------------
p38b_Mmus_p38                      ------------------------------------------------------------
p38a_Mmus_p38                      ------------------------------------------------------------
NLK_Mmus_nmo                       ------------------------------------------------------------
JNK3_Mmus_JNK                      ------------------------------------------------------------
JNK2_Mmus_JNK                      ------------------------------------------------------------
JNK1_Mmus_JNK                      ------------------------------------------------------------
ERK7_Mmus_ERK7                     ------------------------------------------------------------
ERK5_Mmus_ERK5                     ------------------------------------------------------------
ERK4_Mmus_ERK3                     ------------------------------------------------------------
ERK3_Mmus_ERK3                     ------------------------------------------------------------
ERK2_Mmus_ERK1                     ------------------------------------------------------------
ERK1_Mmus_ERK1                     ------------------------------------------------------------
pmk-3_Cele_p38                     ------------------------------------------------------------
pmk-2_Cele_p38                     ------------------------------------------------------------
pmk-1_Cele_p38                     ------------------------------------------------------------
mpk-1_Cele_ERK1                    ------------------------------------------------------------
lit-1_Cele_nmo                     ------------------------------------------------------------
jnk-1_Cele_JNK                     ------------------------------------------------------------
F09C12.2_Cele_MAPK-Unclassified    --------------------------------------TS--------------------
C49C3.10_Cele_JNK                  ------------------------------------------------------------
C05D10.2_Cele_ERK7                 ------------------------------------------------------------
C04G6.1_Cele_MAPK-Unclassified     ------------------------------------------------------------
SMK1_Scer_ERK1                     ------------------------------------------------------------
SLT2_Scer_ERK1                     ------------------------------------------------------------
KSS1_Scer_ERK1                     ------------------------------------------------------------
HOG1_Scer_p38                      ------------------------------------------------------------
FUS3_Scer_ERK1                     ---------------------------------------S--------------------
Erk4_Hsap_ERK3                     ------------------------------------------------------------
Erk3_Hsap_ERK3                     ------------------------------------------------------------
Erk2_Hsap_ERK1                     ------------------------------------------------------------
Erk1_Hsap_ERK1                     ------------------------------------------------------------
T07A9.3_Cele_JNK                   ------------------------------------------------------------
W06B3.2_Cele_MAPK-Unclassified     ------------------------------------------------------------
Y51B9A.9_Cele_JNK                  ------------------------------------------------------------
ZC416.4_Cele_JNK                   ------------------------------------------------------------
YKL161C_Scer_ERK1                  ------------------------------------------------------------
Erk1_Ddis_ERK                      ------------------------------------------------------------
Erk2_Ddis_ERK7                     ------------------------------------------------------------
13785_Tthe_ERK                     ------------------------------------------------------------
18504_Tthe_ERK                     ------------------------------------------------------------
18512_Tthe_ERK                     ------------------------------------------------------------
18725_Tthe_ERK                     ------------------------------------------------------------
23186_Tthe_ERK                     ------------------------------------------------------------
4173_Tthe_ERK                      ------------------------------------------------------------
6784_Tthe_ERK                      ------------------------------------------------------------
28107_Tthe_ERK                     ------------------------------------------------------------
27541_Tthe_ERK7                    ------------------------------------------------------------
28942_Tthe_ERK7                    ------------------------------------------------------------
3210_Tthe_ERK7                     ------------------------------------------------------------
11145_Tthe_MAPK-Unclassified       ----------------------------------KKRSTK--------------------
16370_Tthe_MAPK-Unclassified       ---------------------------------------FSFFTFSLLIGFIIYLTLLRM
23757_Tthe_ERK                     KPNQYLFQTLLSYSLKQFIHNCNQFSLYEFYTVNKK--QA--------------------
13784_Tthe_ERK                     ------------------------------------------------------------
17883_Tthe_ERK                     ------------------------------------------------------------
ERK5_Spur_ERK5                     ------------------------------------------------------------
ERK3_Spur_ERK3                     ------------------------------------------------------------
ERK1_Spur_ERK1                     ------------------------------------------------------------
ERK7_Spur_ERK7                     ------------------------------------------------------------
JNK_Spur_JNK                       ------------------------------------------------------------
NLK_Spur_nmo                       ------------------------------------------------------------
p38_Spur_p38                       ------------------------------------------------------------
CC1G_02007_Ccin_ERK1               ------------------------------------------------------------
CC1G_14865_Ccin_MAPK-Unclassified  ------------------------------------------------------------
CC1G_03633_Ccin_MAPK-Unclassified  ------------------------------------------------------------
CC1G_07620_Ccin_MAPK-Unclassified  ------------------------------------------------------------
CC1G_00577_Ccin_MAPK-Unclassified  ------------------------------------------------------------
AqueK118_Aque_ERK1                 ------------------------------------------------------------
AqueK119_Aque_ERK1                 ------------------------------------------------------------
AqueK120_Aque_ERK1                 ------------------------------------------------------------
AqueK121_Aque_ERK5                 ------------------------------------------------------------
AqueK122_Aque_ERK7                 ------------------------------------------------------------
AqueK123_Aque_ERK7                 ------------------------------------------------------------
AqueK124_Aque_ERK7                 -----------------------------------G--GD--------------------
AqueK125_Aque_ERK7                 -----------------------------------G--GD--------------------
AqueK126_Aque_ERK7                 -----------------------------------G--GD--------------------
AqueK127_Aque_JNK                  ------------------------------------------------------------
AqueK128_Aque_nmo                  ------------------------------------------------------------
AqueK129_Aque_p38                  ------------------------------------------------------------
AqueK130_Aque_p38                  ------------------------------------------------------------
AqueK131_Aque_p38                  ------------------------------------------------------------
ERK-p2-2_Smoe_ERK1                 ------------------------------------------------------------
ERK-Un_Smoe_ERK1                   ------------------------------------------------------------
ERK5_b_Smoe_ERK1                   ------------------------------------------------------------
ERK-p1_a-2_Smoe_ERK1               ------------------------------------------------------------
ERK5_a-2_Smoe_ERK1                 ------------------------------------------------------------
ERK-p1_b-1_Smoe_ERK1               ------------------------------------------------------------
ERK7_Smoe_ERK1                     ------------------------------------------------------------
ERK5_a-1_Smoe_ERK1                 ------------------------------------------------------------
ERK5_c_Smoe_ERK1                   ------------------------------------------------------------
ERK-p2-1_Smoe_ERK1                 ------------------------------------------------------------
ERK-p1_a-1_Smoe_ERK1               ------------------------------------------------------------
ERK-p1_b-2_Smoe_ERK1               ------------------------------------------------------------
GK037_Glam_ERK1                    ------------------------------------------------------------
GK038_Glam_ERK7                    ------------------------------------------------------------


p38g_Hsap_p38                      ------------------------------------------------------------
p38d_Hsap_p38                      ------------------------------------------------------------
p38b_Hsap_p38                      ------------------------------------------------------------
p38a_Hsap_p38                      ------------------------------------------------------------
NLK_Hsap_nmo                       ------------------------------------------------------------
JNK3_Hsap_JNK                      ------------------------------------------------------------
JNK2_Hsap_JNK                      ------------------------------------------------------------
JNK1_Hsap_JNK                      ------------------------------------------------------------
Erk7_Hsap_ERK7                     ------------------------------------------------------------
Erk5_Hsap_ERK5                     ------------------------------------------------------------
nmo_Dmel_nmo                       ------------------------------------------------------------
CG2309_Dmel_ERK7                   ------------------------------------------------------------
P38c_Dmel_p38                      ------------------------------------------------------------
Mpk2_Dmel_p38                      ------------------------------------------------------------
p38b_Dmel_p38                      ------------------------------------------------------------
bsk_Dmel_JNK                       ------------------------------------------------------------
rl_Dmel_ERK1                       ------------------------------------------------------------
p38g_Mmus_p38                      ------------------------------------------------------------
p38d_Mmus_p38                      ------------------------------------------------------------
p38b_Mmus_p38                      ------------------------------------------------------------
p38a_Mmus_p38                      ------------------------------------------------------------
NLK_Mmus_nmo                       ------------------------------------------------------------
JNK3_Mmus_JNK                      ------------------------------------------------------------
JNK2_Mmus_JNK                      ------------------------------------------------------------
JNK1_Mmus_JNK                      ------------------------------------------------------------
ERK7_Mmus_ERK7                     ------------------------------------------------------------
ERK5_Mmus_ERK5                     ------------------------------------------------------------
ERK4_Mmus_ERK3                     ------------------------------------------------------------
ERK3_Mmus_ERK3                     ------------------------------------------------------------
ERK2_Mmus_ERK1                     ------------------------------------------------------------
ERK1_Mmus_ERK1                     ------------------------------------------------------------
pmk-3_Cele_p38                     ------------------------------------------------------------
pmk-2_Cele_p38                     ------------------------------------------------------------
pmk-1_Cele_p38                     ------------------------------------------------------------
mpk-1_Cele_ERK1                    ------------------------------------------------------------
lit-1_Cele_nmo                     ------------------------------------------------------------
jnk-1_Cele_JNK                     ------------------------------------------------------------
F09C12.2_Cele_MAPK-Unclassified    ------------------------------------------------------------
C49C3.10_Cele_JNK                  ------------------------------------------------------------
C05D10.2_Cele_ERK7                 ------------------------------------------------------------
C04G6.1_Cele_MAPK-Unclassified     ------------------------------------------------------------
SMK1_Scer_ERK1                     ------------------------------------------------------------
SLT2_Scer_ERK1                     ------------------------------------------------------------
KSS1_Scer_ERK1                     ------------------------------------------------------------
HOG1_Scer_p38                      ------------------------------------------------------------
FUS3_Scer_ERK1                     ------------------------------------------------------------
Erk4_Hsap_ERK3                     ------------------------------------------------------------
Erk3_Hsap_ERK3                     ------------------------------------------------------------
Erk2_Hsap_ERK1                     ------------------------------------------------------------
Erk1_Hsap_ERK1                     ------------------------------------------------------------
T07A9.3_Cele_JNK                   ------------------------------------------------------------
W06B3.2_Cele_MAPK-Unclassified     ------------------------------------------------------------
Y51B9A.9_Cele_JNK                  ------------------------------------------------------------
ZC416.4_Cele_JNK                   ------------------------------------------------------------
YKL161C_Scer_ERK1                  ------------------------------------------------------------
Erk1_Ddis_ERK                      ------------------------------------------------------------
Erk2_Ddis_ERK7                     ------------------------------------------------------------
13785_Tthe_ERK                     ------------------------------------------------------------
18504_Tthe_ERK                     ------------------------------------------------------------
18512_Tthe_ERK                     ------------------------------------------------------------
18725_Tthe_ERK                     ------------------------------------------------------------
23186_Tthe_ERK                     ------------------------------------------------------------
4173_Tthe_ERK                      ------------------------------------------------------------
6784_Tthe_ERK                      ------------------------------------------------------------
28107_Tthe_ERK                     ------------------------------------------------------------
27541_Tthe_ERK7                    ------------------------------------------------------------
28942_Tthe_ERK7                    ------------------------------------------------------------
3210_Tthe_ERK7                     ------------------------------------------------------------
11145_Tthe_MAPK-Unclassified       ------------------------------------------------------------
16370_Tthe_MAPK-Unclassified       KMILLLLFLKYHKAMTSRSRCLNKHYSKILLKLKKNLHIEDDLQEFILKTRIKLLNEQSS
23757_Tthe_ERK                     ------------------------------------------------------------
13784_Tthe_ERK                     ------------------------------------------------------------
17883_Tthe_ERK                     ------------------------------------------------------------
ERK5_Spur_ERK5                     ------------------------------------------------------------
ERK3_Spur_ERK3                     ------------------------------------------------------------
ERK1_Spur_ERK1                     ------------------------------------------------------------
ERK7_Spur_ERK7                     ------------------------------------------------------------
JNK_Spur_JNK                       ------------------------------------------------------------
NLK_Spur_nmo                       ------------------------------------------------------------
p38_Spur_p38                       ------------------------------------------------------------
CC1G_02007_Ccin_ERK1               ------------------------------------------------------------
CC1G_14865_Ccin_MAPK-Unclassified  ------------------------------------------------------------
CC1G_03633_Ccin_MAPK-Unclassified  ------------------------------------------------------------
CC1G_07620_Ccin_MAPK-Unclassified  ------------------------------------------------------------
CC1G_00577_Ccin_MAPK-Unclassified  ------------------------------------------------------------
AqueK118_Aque_ERK1                 ------------------------------------------------------------
AqueK119_Aque_ERK1                 ------------------------------------------------------------
AqueK120_Aque_ERK1                 ------------------------------------------------------------
AqueK121_Aque_ERK5                 ------------------------------------------------------------
AqueK122_Aque_ERK7                 ------------------------------------------------------------
AqueK123_Aque_ERK7                 ------------------------------------------------------------
AqueK124_Aque_ERK7                 ------------------------------------------------------------
AqueK125_Aque_ERK7                 ------------------------------------------------------------
AqueK126_Aque_ERK7                 ------------------------------------------------------------
AqueK127_Aque_JNK                  ------------------------------------------------------------
AqueK128_Aque_nmo                  ------------------------------------------------------------
AqueK129_Aque_p38                  ------------------------------------------------------------
AqueK130_Aque_p38                  ------------------------------------------------------------
AqueK131_Aque_p38                  ------------------------------------------------------------
ERK-p2-2_Smoe_ERK1                 ------------------------------------------------------------
ERK-Un_Smoe_ERK1                   ------------------------------------------------------------
ERK5_b_Smoe_ERK1                   ------------------------------------------------------------
ERK-p1_a-2_Smoe_ERK1               ------------------------------------------------------------
ERK5_a-2_Smoe_ERK1                 ------------------------------------------------------------
ERK-p1_b-1_Smoe_ERK1               ------------------------------------------------------------
ERK7_Smoe_ERK1                     ------------------------------------------------------------
ERK5_a-1_Smoe_ERK1                 ------------------------------------------------------------
ERK5_c_Smoe_ERK1                   ------------------------------------------------------------
ERK-p2-1_Smoe_ERK1                 ------------------------------------------------------------
ERK-p1_a-1_Smoe_ERK1               ------------------------------------------------------------
ERK-p1_b-2_Smoe_ERK1               ------------------------------------------------------------
GK037_Glam_ERK1                    ------------------------------------------------------------
GK038_Glam_ERK7                    ------------------------------------------------------------


p38g_Hsap_p38                      ------------------------------------------------------------
p38d_Hsap_p38                      ------------------------------------------------------------
p38b_Hsap_p38                      ------------------------------------------------------------
p38a_Hsap_p38                      ------------------------------------------------------------
NLK_Hsap_nmo                       ------------------------------------------------------------
JNK3_Hsap_JNK                      ------------------------------------------------------------
JNK2_Hsap_JNK                      ------------------------------------------------------------
JNK1_Hsap_JNK                      ------------------------------------------------------------
Erk7_Hsap_ERK7                     ------------------------------------------------------------
Erk5_Hsap_ERK5                     ------------------------------------------------------------
nmo_Dmel_nmo                       ------------------------------------------------------------
CG2309_Dmel_ERK7                   ------------------------------------------------------------
P38c_Dmel_p38                      ------------------------------------------------------------
Mpk2_Dmel_p38                      ------------------------------------------------------------
p38b_Dmel_p38                      ------------------------------------------------------------
bsk_Dmel_JNK                       ------------------------------------------------------------
rl_Dmel_ERK1                       ------------------------------------------------------------
p38g_Mmus_p38                      ------------------------------------------------------------
p38d_Mmus_p38                      ------------------------------------------------------------
p38b_Mmus_p38                      ------------------------------------------------------------
p38a_Mmus_p38                      ------------------------------------------------------------
NLK_Mmus_nmo                       ------------------------------------------------------------
JNK3_Mmus_JNK                      ------------------------------------------------------------
JNK2_Mmus_JNK                      ------------------------------------------------------------
JNK1_Mmus_JNK                      ------------------------------------------------------------
ERK7_Mmus_ERK7                     ------------------------------------------------------------
ERK5_Mmus_ERK5                     ------------------------------------------------------------
ERK4_Mmus_ERK3                     ------------------------------------------------------------
ERK3_Mmus_ERK3                     ------------------------------------------------------------
ERK2_Mmus_ERK1                     ------------------------------------------------------------
ERK1_Mmus_ERK1                     ------------------------------------------------------------
pmk-3_Cele_p38                     ------------------------------------------------------------
pmk-2_Cele_p38                     ------------------------------------------------------------
pmk-1_Cele_p38                     ------------------------------------------------------------
mpk-1_Cele_ERK1                    ------------------------------------------------------------
lit-1_Cele_nmo                     ------------------------------------------------------------
jnk-1_Cele_JNK                     ------------------------------------------------------------
F09C12.2_Cele_MAPK-Unclassified    ------------------------------------------------------------
C49C3.10_Cele_JNK                  ------------------------------------------------------------
C05D10.2_Cele_ERK7                 ------------------------------------------------------------
C04G6.1_Cele_MAPK-Unclassified     ------------------------------------------------------------
SMK1_Scer_ERK1                     ------------------------------------------------------------
SLT2_Scer_ERK1                     ------------------------------------------------------------
KSS1_Scer_ERK1                     ------------------------------------------------------------
HOG1_Scer_p38                      ------------------------------------------------------------
FUS3_Scer_ERK1                     ------------------------------------------------------------
Erk4_Hsap_ERK3                     ------------------------------------------------------------
Erk3_Hsap_ERK3                     ------------------------------------------------------------
Erk2_Hsap_ERK1                     ------------------------------------------------------------
Erk1_Hsap_ERK1                     ------------------------------------------------------------
T07A9.3_Cele_JNK                   ------------------------------------------------------------
W06B3.2_Cele_MAPK-Unclassified     ------------------------------------------------------------
Y51B9A.9_Cele_JNK                  ------------------------------------------------------------
ZC416.4_Cele_JNK                   ------------------------------------------------------------
YKL161C_Scer_ERK1                  ------------------------------------------------------------
Erk1_Ddis_ERK                      ------------------------------------------------------------
Erk2_Ddis_ERK7                     ------------------------------------------------------------
13785_Tthe_ERK                     ------------------------------------------------------------
18504_Tthe_ERK                     ------------------------------------------------------------
18512_Tthe_ERK                     ------------------------------------------------------------
18725_Tthe_ERK                     ------------------------------------------------------------
23186_Tthe_ERK                     ------------------------------------------------------------
4173_Tthe_ERK                      ------------------------------------------------------------
6784_Tthe_ERK                      ------------------------------------------------------------
28107_Tthe_ERK                     ------------------------------------------------------------
27541_Tthe_ERK7                    ------------------------------------------------------------
28942_Tthe_ERK7                    ------------------------------------------------------------
3210_Tthe_ERK7                     ------------------------------------------------------------
11145_Tthe_MAPK-Unclassified       ---------------PA-------------------------------------------
16370_Tthe_MAPK-Unclassified       LFLKKQNKQQKSTQHSSFHDEFSQQIDDNLAILVNQENIIQDQQQIVKAIETKKERKNKN
23757_Tthe_ERK                     ------------------------------------------------------------
13784_Tthe_ERK                     ------------------------------------------------------------
17883_Tthe_ERK                     ------------------------------------------------------------
ERK5_Spur_ERK5                     ------------------------------------------------------------
ERK3_Spur_ERK3                     ------------------------------------------------------------
ERK1_Spur_ERK1                     ------------------------------------------------------------
ERK7_Spur_ERK7                     ------------------------------------------------------------
JNK_Spur_JNK                       ------------------------------------------------------------
NLK_Spur_nmo                       ------------------------------------------------------------
p38_Spur_p38                       ------------------------------------------------------------
CC1G_02007_Ccin_ERK1               ------------------------------------------------------------
CC1G_14865_Ccin_MAPK-Unclassified  ------------------------------------------------------------
CC1G_03633_Ccin_MAPK-Unclassified  ------------------------------------------------------------
CC1G_07620_Ccin_MAPK-Unclassified  ------------------------------------------------------------
CC1G_00577_Ccin_MAPK-Unclassified  ------------------------------------------------------------
AqueK118_Aque_ERK1                 ------------------------------------------------------------
AqueK119_Aque_ERK1                 ------------------------------------------------------------
AqueK120_Aque_ERK1                 ------------------------------------------------------------
AqueK121_Aque_ERK5                 ------------------------------------------------------------
AqueK122_Aque_ERK7                 ------------------------------------------------------------
AqueK123_Aque_ERK7                 ------------------------------------------------------------
AqueK124_Aque_ERK7                 ------------------------------------------------------------
AqueK125_Aque_ERK7                 ------------------------------------------------------------
AqueK126_Aque_ERK7                 ------------------------------------------------------------
AqueK127_Aque_JNK                  ------------------------------------------------------------
AqueK128_Aque_nmo                  ------------------------------------------------------------
AqueK129_Aque_p38                  ------------------------------------------------------------
AqueK130_Aque_p38                  ------------------------------------------------------------
AqueK131_Aque_p38                  ------------------------------------------------------------
ERK-p2-2_Smoe_ERK1                 ------------------------------------------------------------
ERK-Un_Smoe_ERK1                   ------------------------------------------------------------
ERK5_b_Smoe_ERK1                   ------------------------------------------------------------
ERK-p1_a-2_Smoe_ERK1               ------------------------------------------------------------
ERK5_a-2_Smoe_ERK1                 ------------------------------------------------------------
ERK-p1_b-1_Smoe_ERK1               ------------------------------------------------------------
ERK7_Smoe_ERK1                     ------------------------------------------------------------
ERK5_a-1_Smoe_ERK1                 ------------------------------------------------------------
ERK5_c_Smoe_ERK1                   ------------------------------------------------------------
ERK-p2-1_Smoe_ERK1                 ------------------------------------------------------------
ERK-p1_a-1_Smoe_ERK1               ------------------------------------------------------------
ERK-p1_b-2_Smoe_ERK1               ------------------------------------------------------------
GK037_Glam_ERK1                    ------------------------------------------------------------
GK038_Glam_ERK7                    ------------------------------------------------------------


p38g_Hsap_p38                      ------------------------------------------------------------
p38d_Hsap_p38                      ------------------------------------------------------------
p38b_Hsap_p38                      ------------------------------------------------------------
p38a_Hsap_p38                      ------------------------------------------------------------
NLK_Hsap_nmo                       ------------------------------------------------------------
JNK3_Hsap_JNK                      ------------------------------------------------------------
JNK2_Hsap_JNK                      ------------------------------------------------------------
JNK1_Hsap_JNK                      ------------------------------------------------------------
Erk7_Hsap_ERK7                     ------------------------------------------------------------
Erk5_Hsap_ERK5                     ------------------------------------------------------------
nmo_Dmel_nmo                       ------------------------------------------------------------
CG2309_Dmel_ERK7                   ------------------------------------------------------------
P38c_Dmel_p38                      ------------------------------------------------------------
Mpk2_Dmel_p38                      ------------------------------------------------------------
p38b_Dmel_p38                      ------------------------------------------------------------
bsk_Dmel_JNK                       ------------------------------------------------------------
rl_Dmel_ERK1                       ------------------------------------------------------------
p38g_Mmus_p38                      ------------------------------------------------------------
p38d_Mmus_p38                      ------------------------------------------------------------
p38b_Mmus_p38                      ------------------------------------------------------------
p38a_Mmus_p38                      ------------------------------------------------------------
NLK_Mmus_nmo                       ------------------------------------------------------------
JNK3_Mmus_JNK                      ------------------------------------------------------------
JNK2_Mmus_JNK                      ------------------------------------------------------------
JNK1_Mmus_JNK                      ------------------------------------------------------------
ERK7_Mmus_ERK7                     ------------------------------------------------------------
ERK5_Mmus_ERK5                     ------------------------------------------------------------
ERK4_Mmus_ERK3                     ------------------------------------------------------------
ERK3_Mmus_ERK3                     ------------------------------------------------------------
ERK2_Mmus_ERK1                     ------------------------------------------------------------
ERK1_Mmus_ERK1                     ------------------------------------------------------------
pmk-3_Cele_p38                     ------------------------------------------------------------
pmk-2_Cele_p38                     ------------------------------------------------------------
pmk-1_Cele_p38                     ------------------------------------------------------------
mpk-1_Cele_ERK1                    ------------------------------------------------------------
lit-1_Cele_nmo                     ------------------------------------------------------------
jnk-1_Cele_JNK                     ------------------------------------------------------------
F09C12.2_Cele_MAPK-Unclassified    ------------------------------------------------------------
C49C3.10_Cele_JNK                  ------------------------------------------------------------
C05D10.2_Cele_ERK7                 ------------------------------------------------------------
C04G6.1_Cele_MAPK-Unclassified     ------------------------------------------------------------
SMK1_Scer_ERK1                     ------------------------------------------------------------
SLT2_Scer_ERK1                     ------------------------------------------------------------
KSS1_Scer_ERK1                     ------------------------------------------------------------
HOG1_Scer_p38                      ------------------------------------------------------------
FUS3_Scer_ERK1                     ------------------------------------------------------------
Erk4_Hsap_ERK3                     ------------------------------------------------------------
Erk3_Hsap_ERK3                     ------------------------------------------------------------
Erk2_Hsap_ERK1                     ------------------------------------------------------------
Erk1_Hsap_ERK1                     ------------------------------------------------------------
T07A9.3_Cele_JNK                   ------------------------------------------------------------
W06B3.2_Cele_MAPK-Unclassified     ------------------------------------------------------------
Y51B9A.9_Cele_JNK                  ------------------------------------------------------------
ZC416.4_Cele_JNK                   ------------------------------------------------------------
YKL161C_Scer_ERK1                  ------------------------------------------------------------
Erk1_Ddis_ERK                      ------------------------------------------------------------
Erk2_Ddis_ERK7                     ------------------------------------------------------------
13785_Tthe_ERK                     ------------------------------------------------------------
18504_Tthe_ERK                     ------------------------------------------------------------
18512_Tthe_ERK                     ------------------------------------------------------------
18725_Tthe_ERK                     ------------------------------------------------------------
23186_Tthe_ERK                     ------------------------------------------------------------
4173_Tthe_ERK                      ------------------------------------------------------------
6784_Tthe_ERK                      ------------------------------------------------------------
28107_Tthe_ERK                     ------------------------------------------------------------
27541_Tthe_ERK7                    ------------------------------------------------------------
28942_Tthe_ERK7                    ------------------------------------------------------------
3210_Tthe_ERK7                     ------------------------------------------------------------
11145_Tthe_MAPK-Unclassified       ------------------------------------------------------------
16370_Tthe_MAPK-Unclassified       RYFSKQNSKIKFYEKKTQRNLNNYQQASNQLLQKADRQIDQKFLCIEGAHIYDDRNSNSP
23757_Tthe_ERK                     ------------------------------------------------------------
13784_Tthe_ERK                     ------------------------------------------------------------
17883_Tthe_ERK                     ------------------------------------------------------------
ERK5_Spur_ERK5                     ------------------------------------------------------------
ERK3_Spur_ERK3                     ------------------------------------------------------------
ERK1_Spur_ERK1                     ------------------------------------------------------------
ERK7_Spur_ERK7                     ------------------------------------------------------------
JNK_Spur_JNK                       ------------------------------------------------------------
NLK_Spur_nmo                       ------------------------------------------------------------
p38_Spur_p38                       ------------------------------------------------------------
CC1G_02007_Ccin_ERK1               ------------------------------------------------------------
CC1G_14865_Ccin_MAPK-Unclassified  ------------------------------------------------------------
CC1G_03633_Ccin_MAPK-Unclassified  ------------------------------------------------------------
CC1G_07620_Ccin_MAPK-Unclassified  ------------------------------------------------------------
CC1G_00577_Ccin_MAPK-Unclassified  ------------------------------------------------------------
AqueK118_Aque_ERK1                 ------------------------------------------------------------
AqueK119_Aque_ERK1                 ------------------------------------------------------------
AqueK120_Aque_ERK1                 ------------------------------------------------------------
AqueK121_Aque_ERK5                 ------------------------------------------------------------
AqueK122_Aque_ERK7                 ------------------------------------------------------------
AqueK123_Aque_ERK7                 ------------------------------------------------------------
AqueK124_Aque_ERK7                 ------------------------------------------------------------
AqueK125_Aque_ERK7                 ------------------------------------------------------------
AqueK126_Aque_ERK7                 ------------------------------------------------------------
AqueK127_Aque_JNK                  ------------------------------------------------------------
AqueK128_Aque_nmo                  ------------------------------------------------------------
AqueK129_Aque_p38                  ------------------------------------------------------------
AqueK130_Aque_p38                  ------------------------------------------------------------
AqueK131_Aque_p38                  ------------------------------------------------------------
ERK-p2-2_Smoe_ERK1                 ------------------------------------------------------------
ERK-Un_Smoe_ERK1                   ------------------------------------------------------------
ERK5_b_Smoe_ERK1                   ------------------------------------------------------------
ERK-p1_a-2_Smoe_ERK1               ------------------------------------------------------------
ERK5_a-2_Smoe_ERK1                 ------------------------------------------------------------
ERK-p1_b-1_Smoe_ERK1               ------------------------------------------------------------
ERK7_Smoe_ERK1                     ------------------------------------------------------------
ERK5_a-1_Smoe_ERK1                 ------------------------------------------------------------
ERK5_c_Smoe_ERK1                   ------------------------------------------------------------
ERK-p2-1_Smoe_ERK1                 ------------------------------------------------------------
ERK-p1_a-1_Smoe_ERK1               ------------------------------------------------------------
ERK-p1_b-2_Smoe_ERK1               ------------------------------------------------------------
GK037_Glam_ERK1                    ------------------------------------------------------------
GK038_Glam_ERK7                    ------------------------------------------------------------


p38g_Hsap_p38                      -------------------------------------EMTG-YVVTRWYRAPEVILNW--
p38d_Hsap_p38                      -------------------------------------EMTG-YVVTRWYRAPEVILSW--
p38b_Hsap_p38                      -------------------------------------EMTG-YVATRWYRAPEIMLNW--
p38a_Hsap_p38                      -------------------------------------EMTG-YVATRWYRAPEIMLNW--
NLK_Hsap_nmo                       ----------------------------------ESRHMTQ-EVVTQYYRAPEILMGS--
JNK3_Hsap_JNK                      -----------------------------------SFMMTP-YVVTRYYRAPEVILG---
JNK2_Hsap_JNK                      -----------------------------------NFMMTP-YVVTRYYRAPEVILG---
JNK1_Hsap_JNK                      -----------------------------------SFMMTP-YVVTRYYRAPEVILG---
Erk7_Hsap_ERK7                     -------------------------------EGPEDQAVTE-YVATRWYRAPEVLLSS--
Erk5_Hsap_ERK5                     ---------------------------------EHQYFMTE-YVATRWYRAPELMLSL--
nmo_Dmel_nmo                       ----------------------------------QAKHMTQ-EVVTQYYRAPEILMGA--
CG2309_Dmel_ERK7                   -------------------------------DLEQDGMLTD-YVATRWYRAPEILVAS--
P38c_Dmel_p38                      -------------------------------------KMTD-HVGTMWYLAPEIIFLR--
Mpk2_Dmel_p38                      -------------------------------------EMTG-YVATRWYRAPEIMLNW--
p38b_Dmel_p38                      -------------------------------------EMTG-YVATRWYRAPEIMLNW--
bsk_Dmel_JNK                       -----------------------------------TFMMTP-YVVTRYYRAPEVILG---
rl_Dmel_ERK1                       --------------------------------HDHTGFLTE-YVATRWYRAPEIMLNS--
p38g_Mmus_p38                      -------------------------------------EMTG-YVVTRWYRAPEVILNW--
p38d_Mmus_p38                      -------------------------------------EMTG-YVVTRWYRAPEVILSW--
p38b_Mmus_p38                      -------------------------------------EMTG-YVATRWYRAPEIMLNW--
p38a_Mmus_p38                      -------------------------------------EMTG-YVATRWYRAPEIMLNW--
NLK_Mmus_nmo                       ----------------------------------ESRHMTQ-EVVTQYYRAPEILMGS--
JNK3_Mmus_JNK                      -----------------------------------SFMMTP-YVVTRYYRAPEVILG---
JNK2_Mmus_JNK                      -----------------------------------NFMMTP-YVVTRYYRAPEVILG---
JNK1_Mmus_JNK                      -----------------------------------SFMMTP-YVVTRYYRAPEVILG---
ERK7_Mmus_ERK7                     -------------------------------EGPGGQALTE-YVATRWYRAPEVLLSS--
ERK5_Mmus_ERK5                     ---------------------------------EHQYFMTE-YVATRWYRAPELMLSL--
ERK4_Mmus_ERK3                     ---------------------------------SHKGYLSE-GLVTKWYRSPRLLLSP--
ERK3_Mmus_ERK3                     ---------------------------------SHKGHLSE-GLVTKWYRSPRLLLSP--
ERK2_Mmus_ERK1                     --------------------------------HDHTGFLTE-YVATRWYRAPEIMLNS--
ERK1_Mmus_ERK1                     --------------------------------HDHTGFLTE-YVATRWYRAPEIMLNS--
pmk-3_Cele_p38                     ------------------------------------TSLTQ-YVQTRWYRSPEVIYWK--
pmk-2_Cele_p38                     -------------------------------------EMTG-YVATRWYRAPEIMLNW--
pmk-1_Cele_p38                     -------------------------------------EMTG-YVATRWYRAPEIMLNW--
mpk-1_Cele_ERK1                    --------------------------------TDHTGFLTE-YVATRWYRAPEIMLNS--
lit-1_Cele_nmo                     ----------------------------------DRLNMTH-EVVTQYYRAPELLMGA--
jnk-1_Cele_JNK                     -----------------------------------AFMMTP-YVVTRYYRAPEVILG---
F09C12.2_Cele_MAPK-Unclassified    -----------------------------P-NAHISGDLSQ-YVSTLWYRAPEILLSM--
C49C3.10_Cele_JNK                  ------------------------------------TSNTP-YIVQRFYRAPEIICET--
C05D10.2_Cele_ERK7                 -------------------------------EGQKMPDLTE-YVATRWYRSPEILLAA--
C04G6.1_Cele_MAPK-Unclassified     -----------------------------D-DANVGGHMTQ-YVSTRWYRAPEILFSM--
SMK1_Scer_ERK1                     -----------------------------C-HSTVQPHITN-YVATRWYRAPELLLSN--
SLT2_Scer_ERK1                     --------------------------------VENSQFLTE-YVATRWYRAPEIMLSY--
KSS1_Scer_ERK1                     -------------------------------RETLVGFMTE-YVATRWYRAPEIMLTF--
HOG1_Scer_p38                      -------------------------------------QMTG-YVSTRYYRAPEIMLTW--
FUS3_Scer_ERK1                     -----------------------------E-PTGQQSGMTE-YVATRWYRAPEVMLTS--
Erk4_Hsap_ERK3                     ---------------------------------SHKGYLSE-GLVTKWYRSPRLLLSP--
Erk3_Hsap_ERK3                     ---------------------------------SHKGHLSE-GLVTKWYRSPRLLLSP--
Erk2_Hsap_ERK1                     --------------------------------HDHTGFLTE-YVATRWYRAPEIMLNS--
Erk1_Hsap_ERK1                     --------------------------------HDHTGFLTE-YVATRWYRAPEIMLNS--
T07A9.3_Cele_JNK                   -----------------------------------SMRMSD-YVVTRYYRAPEVILG---
W06B3.2_Cele_MAPK-Unclassified     -----------------------------D-DEEHCYYMTQ-HVATLPYRAPELLFVL--
Y51B9A.9_Cele_JNK                  ------------------------------------FVNTP-YIVQRFYRAPEILCET--
ZC416.4_Cele_JNK                   -----------------------------------DMRMSD-YVGTRYYRAPEVILG---
YKL161C_Scer_ERK1                  --------------------------------KVNDGFIKG-YITSIWYKAPEILLNY--
Erk1_Ddis_ERK                      ----------------------------------HQGFMTE-YVATRWYRAPEVILSW--
Erk2_Ddis_ERK7                     -------------------------------IAEANPVLTE-YVATRWYRAPEILLGS--
13785_Tthe_ERK                     -------------------------------------IYSQ-YITSDYFLSPQQILNL--
18504_Tthe_ERK                     --------------------------------KCRAGMLTD-YVATRWYRAPELLLSW--
18512_Tthe_ERK                     ----------------------------------TKNDLTD-YVTTRWYRPPELLLSW--
18725_Tthe_ERK                     -----------------------------------GESLTE-YVITRWYRAPEVILNA--
23186_Tthe_ERK                     ---------------------------------NVLVLMTE-YVATRWYRAPELLLSW--
4173_Tthe_ERK                      -----------------------------Q-QISLNLYFTT-YVVTRPYRAPEILLST--
6784_Tthe_ERK                      -----------------------------------EDGKTE-YVVTRWYRAPEVILKA--
28107_Tthe_ERK                     ----------------------------------RVNDLSE-YVTARWYRAPEILLSY--
27541_Tthe_ERK7                    --------------------------------DDAPPVLTE-YVATRWYRAPEILLGS--
28942_Tthe_ERK7                    --------------------------------DDDNPVRTE-YVATRWYRAPEILLGS--
3210_Tthe_ERK7                     --------------------------------NGSTPILTE-YIATRWYRAPEILLGIIE
11145_Tthe_MAPK-Unclassified       ----------------------------------FQEQKSL-NSGSRYYRAPEIILLN--
16370_Tthe_MAPK-Unclassified       QKQQTSSQSPEKPAATSSGRPKLSKEKGIN-SKTTKRELTG-HVVTRWYRAPELILLE--
23757_Tthe_ERK                     -----------------------------S-KQINTCQLTE-YVVTRYYRAPEIMLS---
13784_Tthe_ERK                     -------------------------------------FDKK-YINTNSYLSPYYILGL--
17883_Tthe_ERK                     --------------------------------------EVN-YYNKKGYYPPQRILEL--
ERK5_Spur_ERK5                     --------------------------------DKKKMFMTS-YVATRWYRAPELLFSS--
ERK3_Spur_ERK3                     ---------------------------------SHKGYLTQ-NVSTQWYRSPELVLQP--
ERK1_Spur_ERK1                     --------------------------------HDHTGFLTE-YVATRWYRAPEIMLNS--
ERK7_Spur_ERK7                     -------------------------------LSEDNPALTE-YVATRWYRAPEILLAS--
JNK_Spur_JNK                       -----------------------------------SFMMTP-YVVTRYYRAPEVILG---
NLK_Spur_nmo                       ----------------------------------TSKHMTQ-EVVTQYYRAPEILVGS--
p38_Spur_p38                       -------------------------------------EMTG-YVATRWYRAPEIMLNW--
CC1G_02007_Ccin_ERK1               -----------------------------R-AAGNQGFMTE-YVATRWYRAPEIMLSF--
CC1G_14865_Ccin_MAPK-Unclassified  --------------------------------DENATRLTE-YVATRWYRAPEIMLAF--
CC1G_03633_Ccin_MAPK-Unclassified  -------------------------------AGKEVGLMTE-YVATRWYRAPEIMLSF--
CC1G_07620_Ccin_MAPK-Unclassified  -------------------------------SGTETGFMTE-YVATRWYRAPEIMLTF--
CC1G_00577_Ccin_MAPK-Unclassified  -------------------------------------QMTG-YVSTRYYRAPEIMLTW--
AqueK118_Aque_ERK1                 --------------------------------QDHTGILTE-YVATRWYRAPEIMLNS--
AqueK119_Aque_ERK1                 -------------------------------NFELLRFTDSYRVEHLHYWAPEVLIN---
AqueK120_Aque_ERK1                 -------------------------------CGEEYNWTGSSTEGSWQYLSPQAVCY---
AqueK121_Aque_ERK5                 ---------------------------------DHALFLTE-YVATRWYRAPELMLSF--
AqueK122_Aque_ERK7                 ------------------------------------------------------------
AqueK123_Aque_ERK7                 ------------------------------------xx-------xxxxxxxxxxx-x--
AqueK124_Aque_ERK7                 -----------------------------G-VSDFNPAMTD-YVATHWYRSPEILLGS--
AqueK125_Aque_ERK7                 -----------------------------G-VNDFNPAMTD-YVATRWYRSPEILLGS--
AqueK126_Aque_ERK7                 -----------------------------G-VSDFNPAMTD-YVATRWYRSPEILLGS--
AqueK127_Aque_JNK                  -----------------------------------AFMMTP-YVVTRYYRAPEVIVG---
AqueK128_Aque_nmo                  ----------------------------------PRTPMTL-EVVTQYYRAPELLAGC--
AqueK129_Aque_p38                  -------------------------------------EMTG-YVATRYWRAPEIMLNW--
AqueK130_Aque_p38                  -------------------------------------EMTG-YVTTRFWRAPEVLLQW--
AqueK131_Aque_p38                  -------------------------------------DMTG-YVSTRHYRAPEIMLSW--
ERK-p2-2_Smoe_ERK1                 -----------------------------------TDYMTE-YVVTRWYRAPELLLNC--
ERK-Un_Smoe_ERK1                   ----------------------------------------E-EVVTPSYRAPEVIMSR--
ERK5_b_Smoe_ERK1                   -----------------------------------AIFWTD-YVATRWYRAPELCGSF--
ERK-p1_a-2_Smoe_ERK1               -----------------------------------GQFMTE-YVVTRWYRAPELLLSC--
ERK5_a-2_Smoe_ERK1                 -----------------------------GWTYLTLLFFKD-YVATRWYRAPELCGSF--
ERK-p1_b-1_Smoe_ERK1               -----------------------------------GQFMTE-YVVTRWYRAPELLLSC--
ERK7_Smoe_ERK1                     -------------------------------DMGQAQVLTD-YVATRWYRAPEILLGS--
ERK5_a-1_Smoe_ERK1                 -----------------------------GWTYLTLLFFKD-YVATRWYRAPELCGSF--
ERK5_c_Smoe_ERK1                   -----------------------------------AIFWTD-YVATRWYRAPELCGSF--
ERK-p2-1_Smoe_ERK1                 -----------------------------------TDYMTE-YVVTRWYRAPELLLNC--
ERK-p1_a-1_Smoe_ERK1               -----------------------------------GQFMTE-YVVTRWYRAPELLLSC--
ERK-p1_b-2_Smoe_ERK1               -----------------------------------GQFMTE-YVVTRWYRAPELLLSC--
GK037_Glam_ERK1                    -----------------------------D-AEKHDTQMTE-YVATRWYRAPEIILGW--
GK038_Glam_ERK7                    -------------------------------SSATNPILTD-YVATRWYRSPEILLGC--


p38g_Hsap_p38                      -----MR-YT-Q----------TVDIWSVGCIMAEMIT-----------GK--------T
p38d_Hsap_p38                      -----MH-YN-Q----------TVDIWSVGCIMAEMLT-----------GK--------T
p38b_Hsap_p38                      -----MH-YN-Q----------TVDIWSVGCIMAELLQ-----------GK--------A
p38a_Hsap_p38                      -----MH-YN-Q----------TVDIWSVGCIMAELLT-----------GR--------T
NLK_Hsap_nmo                       -----RH-YS-N----------AIDIWSVGCIFAELLG-----------RR--------I
JNK3_Hsap_JNK                      -----MG-YK-E----------NVDIWSVGCIMGEMVR-----------HK--------I
JNK2_Hsap_JNK                      -----MG-YK-E----------NVDIWSVGCIMGELVK-----------GC--------V
JNK1_Hsap_JNK                      -----MG-YK-E----------NVDLWSVGCIMGEMVC-----------HK--------I
Erk7_Hsap_ERK7                     -----HR-YT-L----------GVDMWSLGCILGEMLR-----------GR--------P
Erk5_Hsap_ERK5                     -----HE-YT-Q----------AIDLWSVGCIFGEMLA-----------RR--------Q
nmo_Dmel_nmo                       -----RH-YS-S----------AVDVWSVGCIFGELLG-----------RR--------I
CG2309_Dmel_ERK7                   -----RN-YT-K----------GIDMWGLGCILGEMIR-----------QK--------P
P38c_Dmel_p38                      -----GQ-YT-K----------AIDVWSVGCILAELIT-----------DR--------V
Mpk2_Dmel_p38                      -----MH-YD-Q----------TVDIWSVGCIMAELIT-----------RR--------T
p38b_Dmel_p38                      -----MH-YN-Q----------TADIWSVGCIMAELLT-----------GR--------T
bsk_Dmel_JNK                       -----MG-YT-E----------NVDIWSVGCIMGEMIR-----------GG--------V
rl_Dmel_ERK1                       -----KG-YT-K----------SIDIWSVGCILAEMLS-----------NR--------P
p38g_Mmus_p38                      -----MR-YT-Q----------TVDIWSVGCIMAEMIT-----------GK--------I
p38d_Mmus_p38                      -----MH-YN-Q----------TVDIWSVGCIMAEMLT-----------GK--------T
p38b_Mmus_p38                      -----MH-YN-Q----------TVDIWSVGCIMAELLQ-----------GK--------A
p38a_Mmus_p38                      -----MH-YN-Q----------TVDIWSVGCIMAELLT-----------GR--------T
NLK_Mmus_nmo                       -----RH-YS-N----------AIDIWSVGCIFAELLG-----------RR--------I
JNK3_Mmus_JNK                      -----MG-YK-E----------NVDIWSVGCIMGEMVR-----------HK--------I
JNK2_Mmus_JNK                      -----MG-YK-E----------NVDIWSVGCIMGELVK-----------GC--------V
JNK1_Mmus_JNK                      -----MG-YK-E----------NVDLWSVGCIMGEMVC-----------HK--------I
ERK7_Mmus_ERK7                     -----RW-YT-P----------GVDMWSLGCILGEMLR-----------GQ--------P
ERK5_Mmus_ERK5                     -----HE-YT-Q----------AIDLWSVGCIFGEMLA-----------RR--------Q
ERK4_Mmus_ERK3                     -----NN-YT-K----------AIDMWAAGCILAEMLT-----------GK--------M
ERK3_Mmus_ERK3                     -----NN-YT-K----------AIDMWAAGCIFAEMLT-----------GK--------T
ERK2_Mmus_ERK1                     -----KG-YT-K----------SIDIWSVGCILAEMLS-----------NR--------P
ERK1_Mmus_ERK1                     -----KG-YT-K----------SIDIWSVGCILAEMLS-----------NR--------P
pmk-3_Cele_p38                     ----IDS-YT-N----------LADMWSLGCIAAELLT-----------GE--------P
pmk-2_Cele_p38                     -----MH-YT-Q----------TVDVWSVGCILAELVS-----------GR--------P
pmk-1_Cele_p38                     -----MH-YT-Q----------TVDVWSVGCILAELIT-----------GK--------T
mpk-1_Cele_ERK1                    -----KG-YT-K----------SIDVWSVGCILAEMLS-----------NR--------P
lit-1_Cele_nmo                     -----RR-YT-G----------AVDIWSVGCIFAELLQ-----------RK--------I
jnk-1_Cele_JNK                     -----MG-YK-E----------NVDVWSIGCIFGELIR-----------GR--------V
F09C12.2_Cele_MAPK-Unclassified    -----GE-YD-T----------QVDIWSAGCILAEMLL-----------LR--------P
C49C3.10_Cele_JNK                  -----TDNNK-T----------NVDIWSLGCILAELLT-----------GH--------V
C05D10.2_Cele_ERK7                 -----KR-YT-K----------GVDMWSLGCILAEMLI-----------GR--------A
C04G6.1_Cele_MAPK-Unclassified     -----VE-YD-T----------KVDLWSAGCIFAEMLL-----------RR--------Q
SMK1_Scer_ERK1                     -----QP-YS-K----------SVDIWAVGCILAEFYA-----------RK--------P
SLT2_Scer_ERK1                     -----QG-YT-K----------AIDVWSAGCILAEFLG-----------GK--------P
KSS1_Scer_ERK1                     -----QE-YT-T----------AMDIWSCGCILAEMVS-----------GK--------P
HOG1_Scer_p38                      -----QK-YD-V----------EVDIWSAGCIFAEMIE-----------GK--------P
FUS3_Scer_ERK1                     -----AK-YS-R----------AMDVWSCGCILAELFL-----------RR--------P
Erk4_Hsap_ERK3                     -----NN-YT-K----------AIDMWAAGCILAEMLT-----------GR--------M
Erk3_Hsap_ERK3                     -----NN-YT-K----------AIDMWAAGCIFAEMLT-----------GK--------T
Erk2_Hsap_ERK1                     -----KG-YT-K----------SIDIWSVGCILAEMLS-----------NR--------P
Erk1_Hsap_ERK1                     -----KG-YT-K----------SIDIWSVGCILAEMLS-----------NR--------P
T07A9.3_Cele_JNK                   -----LP-YS-E----------KVDIWSVGCIFAEMIN-----------HT--------V
W06B3.2_Cele_MAPK-Unclassified     -----PE-HS-T----------AVDMWAVGCIFGEMVI-----------RN--------E
Y51B9A.9_Cele_JNK                  -----MDNNK-P----------SVDIWSLGCILAELLT-----------GK--------I
ZC416.4_Cele_JNK                   -----LN-YS-E----------KVDIWSVGCILAEMIN-----------HT--------V
YKL161C_Scer_ERK1                  -----QE-CT-K----------AVDIWSTGCILAELLG-----------RK--------P
Erk1_Ddis_ERK                      -----NK-YT-K----------AIDIWSVGCIFAELLG-----------RK--------P
Erk2_Ddis_ERK7                     -----TK-YT-K----------GVDMWSIGCILGELLG-----------EK--------A
13785_Tthe_ERK                     -----PK-NL-S----------KTDIWHVGVIILGLIN-----------RD--------T
18504_Tthe_ERK                     -----RD-YD-E----------KVDVWSVGCIFAELLR-----------RK--------P
18512_Tthe_ERK                     -----TD-YT-C----------AMDVWSVGIIFAELIK-----------RK--------P
18725_Tthe_ERK                     -----SE-YN-Q----------AVDIWSVGCITAELLG-----------RT--------P
23186_Tthe_ERK                     -----NK-YT-T----------AIDMWAVGCIFSELYM-----------RK--------P
4173_Tthe_ERK                      -----EN-YS-K----------PIDIWSAGCIFAEMMG-----------RK--------T
6784_Tthe_ERK                      -----SK-YT-K----------SIDVWSIGCIFAELLG-----------RT--------P
28107_Tthe_ERK                     -----KK-YD-I----------AVDMWSCGIIMAELLK-----------RQ--------P
27541_Tthe_ERK7                    -----TK-YT-K----------AVDMWSVGCILGELII-----------GK--------S
28942_Tthe_ERK7                    -----TK-YA-K----------AVDMWSIGCIVGELIT-----------NR--------A
3210_Tthe_ERK7                     LSQCSHT-YT-K----------GVDMWSIGCILGQLLL-----------GK--------P
11145_Tthe_MAPK-Unclassified       -----SN-YG-F----------QSDIWSLGCLYAELLQ-----------NYDRHNSLQGI
16370_Tthe_MAPK-Unclassified       -----KD-YT-A----------AIDIWSIGCIFAELMNMIKENSPTFLDRS--------P
23757_Tthe_ERK                     ----SHV-YS-K----------AVDIWSLGCTFAELIS-----------HQ--------I
13784_Tthe_ERK                     -----PE-DF-S----------KTDIWNVGVIILELFQ-----------IK--------N
17883_Tthe_ERK                     -----PE-NL-S----------KTDIWHVGVIILQLLY-----------GY--------P
ERK5_Spur_ERK5                     -----DD-YT-L----------AVDVWSVGCILGEMIG-----------RK--------Q
ERK3_Spur_ERK3                     -----TD-YT-K----------AIDLWSAGCILAEMVT-----------GK--------P
ERK1_Spur_ERK1                     -----KG-YT-K----------SIDIWSVGCILAEMLS-----------NR--------P
ERK7_Spur_ERK7                     -----KR-YT-K----------GVDMWSVGCIIGELLK-----------GK--------P
JNK_Spur_JNK                       -----MG-YK-E----------NVDIWSIGCIFGEMIR-----------GQ--------V
NLK_Spur_nmo                       -----KH-YT-S----------AVDMWSVGCIFAELLG-----------RR--------I
p38_Spur_p38                       -----MH-YT-E----------KVDIWSVGCIMAELLT-----------QK--------T
CC1G_02007_Ccin_ERK1               -----AN-YS-T----------AIDVWSVGCILAELLG-----------GR--------P
CC1G_14865_Ccin_MAPK-Unclassified  -----PKSYQ-LALNFLCLLGILVDVWSIGCILGELLL-----------GK--------P
CC1G_03633_Ccin_MAPK-Unclassified  -----KM-YT-K----------AIDIWAVGCILAELLT-----------GR--------P
CC1G_07620_Ccin_MAPK-Unclassified  -----KQ-YT-K----------AIDVWSVGCILAEMLS-----------GK--------P
CC1G_00577_Ccin_MAPK-Unclassified  -----QK-YD-V----------AVDIWSTGCIFAEMLE-----------GK--------P
AqueK118_Aque_ERK1                 -----KG-YS-K----------AIDIWSVGCILAEMLS-----------NR--------P
AqueK119_Aque_ERK1                 -----EE-IT-P----------VVDIWSAGCIFAELLT-----------GK--------K
AqueK120_Aque_ERK1                 -----DE-QT-T----------ACDIWSAGCVFGEMLL-----------GQ--------P
AqueK121_Aque_ERK5                 -----SQ-YD-I----------SLDMWSVGCIFAEMLG-----------RR--------Q
AqueK122_Aque_ERK7                 ------------------------------------------------------------
AqueK123_Aque_ERK7                 ----xxx-xx-x----------xxxxxxxxxxxxxxxx-----------xx--------x
AqueK124_Aque_ERK7                 -----RR-YT-R----------GVDM---------------------------------P
AqueK125_Aque_ERK7                 -----RR-YT-R----------GVDMWSLGCILAEMIA-----------SR--------P
AqueK126_Aque_ERK7                 -----RR-YT-R----------GVDMWSLGCILAEMIA-----------SK--------P
AqueK127_Aque_JNK                  -----MK-YK-E----------NVDIWSVGCIFAEIVR-----------GD--------I
AqueK128_Aque_nmo                  -----QQ-YG-P----------AIDMWAIGCIVGELLG-----------RK--------I
AqueK129_Aque_p38                  -----MH-YGKE----------GFDMWSVGCIMAELLT-----------GQ--------V
AqueK130_Aque_p38                  -----MH-YD-Q----------KVDIWSVGCILAELLT-----------GR--------V
AqueK131_Aque_p38                  -----EN-YG-K----------QVDVWSVGCIMAELLG-----------SK--------V
ERK-p2-2_Smoe_ERK1                 -----SE-YT-A----------AIDVWSVGCIFMELLN-----------RE--------P
ERK-Un_Smoe_ERK1                   -----GQ-YS-S----------SIDIWSLGCIFWVSVS-----------SN--------D
ERK5_b_Smoe_ERK1                   ----FSR-YT-P----------AIDIWSIGCIFAETIT-----------RK--------P
ERK-p1_a-2_Smoe_ERK1               -----ED-YT-S----------AIDIWSVGCIFAELLG-----------RK--------P
ERK5_a-2_Smoe_ERK1                 ----FSK-YT-P----------AIDIWSIGCIFAEILT-----------GK--------P
ERK-p1_b-1_Smoe_ERK1               -----EE-YT-S----------AIDMWSVGCIFAELLG-----------RK--------P
ERK7_Smoe_ERK1                     -----TN-YT-F----------GVDMWSSGCILGELLN-----------GK--------P
ERK5_a-1_Smoe_ERK1                 ----FSK-YT-P----------AIDIWSIGCIFAEILT-----------GK--------P
ERK5_c_Smoe_ERK1                   ----FSR-YT-P----------AIDIWSIGCIFAETIT-----------RK--------P
ERK-p2-1_Smoe_ERK1                 -----SE-YT-A----------AIDVWSVGCIFMELLN-----------RE--------P
ERK-p1_a-1_Smoe_ERK1               -----ED-YT-S----------AIDIWSVGCIFAELLG-----------RK--------P
ERK-p1_b-2_Smoe_ERK1               -----EE-YT-S----------AIDMWSVGCIFAELLG-----------RK--------P
GK037_Glam_ERK1                    -----PQ-YG-K----------PVDIFSVGCIFAELIA-----------RK--------P
GK038_Glam_ERK7                    -----TR-YT-K----------GVDMWAIGCILGEMLG-----------GS--------P


p38g_Hsap_p38                      LFK------G-SD-----------------------HLD---QLKEIMKVTGTPPAE-FV
p38d_Hsap_p38                      LFK------G-KD-----------------------YLD---QLTQILKVTGVPGTE-FV
p38b_Hsap_p38                      LFP------G-SD-----------------------YID---QLKRIMEVVGTPSPE-VL
p38a_Hsap_p38                      LFP------G-TD-----------------------HID---QLKLILRLVGTPGAE-LL
NLK_Hsap_nmo                       LFQ------A-QS-----------------------PIQ---QLDLITDLLGTPSLE-AM
JNK3_Hsap_JNK                      LFP------G-RD-----------------------YID---QWNKVIEQLGTPCPE-FM
JNK2_Hsap_JNK                      IFQ------G-TD-----------------------HID---QWNKVIEQLGTPSAE-FM
JNK1_Hsap_JNK                      LFP------G-RD-----------------------YID---QWNKVIEQLGTPCPE-FM
Erk7_Hsap_ERK7                     LFP------G-TS-----------------------TLH---QLELILETIPPPSEE-DL
Erk5_Hsap_ERK5                     LFP------G-KN-----------------------YVH---QLQLIMMVLGTPSPA-VI
nmo_Dmel_nmo                       LFQ------A-QN-----------------------PVQ---QLELITELLGTPTME-DM
CG2309_Dmel_ERK7                   LFQ------G-TS-----------------------TVN---QIEKIVTSLPNVTKL-DI
P38c_Dmel_p38                      LFR------G-EN-----------------------YVS---QIRCLINIMGTPTRE-FI
Mpk2_Dmel_p38                      LFP------G-TD-----------------------HIH---QLNLIMEMLGTPPAE-FL
p38b_Dmel_p38                      LFP------G-TD-----------------------HIH---QLNLIMEVLGTPADE-FM
bsk_Dmel_JNK                       LFP------G-TD-----------------------HID---QWNKIIEQLGTPSPS-FM
rl_Dmel_ERK1                       IFP------G-KH-----------------------YLD---QLNHILGVLGSPSRD-DL
p38g_Mmus_p38                      LFK------G-ND-----------------------HLD---QLKEIMKITGTPPPE-FV
p38d_Mmus_p38                      LFK------G-KD-----------------------YLD---QLTQILKVTGVPGAE-FV
p38b_Mmus_p38                      LFP------G-ND-----------------------YID---QLKRIMEVVGTPSPE-VL
p38a_Mmus_p38                      LFP------G-TD-----------------------HIN---QLQQIMRLTGTPPAY-LI
NLK_Mmus_nmo                       LFQ------A-QS-----------------------PIQ---QLDLITDLLGTPSLE-AM
JNK3_Mmus_JNK                      LFP------G-RD-----------------------YID---QWNKVIEQLGTPCPE-FM
JNK2_Mmus_JNK                      IFQ------G-TD-----------------------HID---QWNKVIEQLGTPSAE-FM
JNK1_Mmus_JNK                      LFP------G-RD-----------------------YID---QWNKVIEQLGTPCPE-FM
ERK7_Mmus_ERK7                     LFP------G-TS-----------------------TFH---QLELILKTIPLPSME-EL
ERK5_Mmus_ERK5                     LFP------G-KN-----------------------YVH---QLQLIMMVLGTPSPA-VI
ERK4_Mmus_ERK3                     LFA------G-AH-----------------------ELE---QMQLILDTIPVVREE-DK
ERK3_Mmus_ERK3                     LFA------G-AH-----------------------ELE---QMQLILDSIPVVHEE-DR
ERK2_Mmus_ERK1                     IFP------G-KH-----------------------YLD---QLNHILGILGSPSQE-DL
ERK1_Mmus_ERK1                     IFP------G-KH-----------------------YLD---QLNHILGILGSPSQE-DL
pmk-3_Cele_p38                     LFP------G-DE-----------------------PNA---QYQRITQLCGSPDEE-LL
pmk-2_Cele_p38                     LFP------G-DD-----------------------HID---QLTKIMSVVGTPKEE-FW
pmk-1_Cele_p38                     LFP------G-SD-----------------------HID---QLTRIMSVTGTPDEE-FL
mpk-1_Cele_ERK1                    LFP------G-KH-----------------------YLD---QLNLILAVVGSPSNA-DL
lit-1_Cele_nmo                     LFQ------A-AG-----------------------PIE---QLQMIIDLLGTPSQE-AM
jnk-1_Cele_JNK                     LFP------G-GD-----------------------HID---QWTRIIEQLGTPDRS-FL
F09C12.2_Cele_MAPK-Unclassified    IFT------G-TD-----------------------SYS---QIQLLIEYLGTPDEQ-VI
C49C3.10_Cele_JNK                  LFR------G-KD-----------------------HID---QFILMVQFLGNAGPS-FY
C05D10.2_Cele_ERK7                 LFP------G-SS-----------------------TIN---QIERIMNTIAKPSRA-DI
C04G6.1_Cele_MAPK-Unclassified     LFP------G-KD-----------------------SVS---QIKMIVYYLGSPEEE-VI
SMK1_Scer_ERK1                     VFM------G-RD-----------------------SMH---QIFEIIKVLGTPDKD-IL
SLT2_Scer_ERK1                     IFK------G-KD-----------------------YVN---QLNQILQVLGTPPDE-TL
KSS1_Scer_ERK1                     LFP------G-RD-----------------------YHH---QLWLILEVLGTPSFE-DF
HOG1_Scer_p38                      LFP------G-KD-----------------------HVH---QFSIITDLLGSPPKD-VI
FUS3_Scer_ERK1                     IFP------G-RD-----------------------YRH---QLLLIFGIIGTPHSDNDL
Erk4_Hsap_ERK3                     LFA------G-AH-----------------------ELE---QMQLILETIPVIREE-DK
Erk3_Hsap_ERK3                     LFA------G-AH-----------------------ELE---QMQLILESIPVVHEE-DR
Erk2_Hsap_ERK1                     IFP------G-KH-----------------------YLD---QLNHILGILGSPSQE-DL
Erk1_Hsap_ERK1                     IFP------G-KH-----------------------YLD---QLNHILGILGSPSQE-DL
T07A9.3_Cele_JNK                   LFP------G-KD-----------------------RID---QWTKIYSVLGTPDDH-FI
W06B3.2_Cele_MAPK-Unclassified     ILP------G-RS-----------------------VQG---QIKMLLTMLGQPPQE-VI
Y51B9A.9_Cele_JNK                  LFT------G-QT-----------------------QID---QFFQIVRFLGNPDLS-FY
ZC416.4_Cele_JNK                   LFP------G-KD-----------------------IRD---QWTQISSVLRTPDDH-FI
YKL161C_Scer_ERK1                  MFE------G-KD-----------------------YVD---HLNHILQILGTPPEE-TL
Erk1_Ddis_ERK                      LFQ------G-KD-----------------------YIH---QITLIIETIGSPSEE-DI
Erk2_Ddis_ERK7                     MFP------G-NS-----------------------TMN---QLDLIIEVTGRPSAE-DI
13785_Tthe_ERK                     FFSNLSNQLG-GG-----------------------YLG---LINAIFSYIGTPSGE-EL
18504_Tthe_ERK                     FLP------G-ID-----------------------TRN---QIELIFEYLGTPSEQ-EI
18512_Tthe_ERK                     LLP------G-SS-----------------------SSD---QLLRIFDLIGTPLEN-EI
18725_Tthe_ERK                     LFP------G-EN-----------------------YLD---QVQRVIAVLGTPTQE-DM
23186_Tthe_ERK                     LLP------G-ES-----------------------YLN---QLILTLNLTGTPSKE-DL
4173_Tthe_ERK                      IFK------G-NS-----------------------YVN---QLDRIIAIMGKPDFD-KL
6784_Tthe_ERK                      LFP------G-KD-----------------------YLE---QIQRIIAILGTPTPE-EL
28107_Tthe_ERK                     IIR------G-AS-----------------------TDD---QMRQILQLIGSPDEY-QV
27541_Tthe_ERK7                    IFP------G-VS-----------------------TLN---QIERVLELTGKPKNE-DI
28942_Tthe_ERK7                    IFP------G-NS-----------------------TLN---QIEKVLELTGKPTQE-DI
3210_Tthe_ERK7                     IFA------G-TS-----------------------TLN---QLELILQVTGKPTYE-DI
11145_Tthe_MAPK-Unclassified       LFP------G-QTCNP--------ITPPSKNDSDFLKQD---QLFLIIDKLGRPKKE-DC
16370_Tthe_MAPK-Unclassified       LFP------G-SSCFPLSPDRNNTVKQGGF-PHS--HSD---QLNVIFSVLGTPNEE-DM
23757_Tthe_ERK                     LFK------A-DN-----------------------YIK---QIKLIFDKLGMPPEE-DL
13784_Tthe_ERK                     IFS------D-FC-----------------------CSASGGLLTNYFYYIGSPSKE-DL
17883_Tthe_ERK                     FFE------K-RN-----------------------RGGRNGVLQAYFYSIGSPSEE-DL
ERK5_Spur_ERK5                     MFP------G-KN-----------------------PID---QLSLIVDVLGMPPTH-ML
ERK3_Spur_ERK3                     LFP------G-DH-----------------------DLE---LMMLVLDSVQLND-R-DL
ERK1_Spur_ERK1                     IFP------G-KH-----------------------YLD---QLNHILGVLGSPSQD-DL
ERK7_Spur_ERK7                     MFP------G-S------------------------------------------------
JNK_Spur_JNK                       MFP------G-SD-----------------------HID---QWNKIADLLGTPTDI-FL
NLK_Spur_nmo                       LFQ------A-QS-----------------------PIT---QLNLITDLLGTPSME-DM
p38_Spur_p38                       LFP------G-CD-----------------------HID---QLNKIIAITGKPDET-FL
CC1G_02007_Ccin_ERK1               IFK------G-RD-----------------------YVD---QLNQILHYLGTPSED-TL
CC1G_14865_Ccin_MAPK-Unclassified  LFK------G-KD-----------------------YVD---QLNKILDILGSPDET-II
CC1G_03633_Ccin_MAPK-Unclassified  LFP------G-RD-----------------------YSH---QLDLILDVIGTPSLD-EF
CC1G_07620_Ccin_MAPK-Unclassified  LFP------G-RD-----------------------YHH---QLTLILDVLGTPTLD-EF
CC1G_00577_Ccin_MAPK-Unclassified  LFP------G-KD-----------------------HVN---QFSIITELLGTPPDD-VI
AqueK118_Aque_ERK1                 IFP------G-KH-----------------------YLD---QLNHILNVIGSPTEK-DL
AqueK119_Aque_ERK1                 VFG------S-SD-----------------------VRG---QLDLIVDLLGAPSPE-DL
AqueK120_Aque_ERK1                 LFV------SDAN-----------------------AVN---IFRVIFSTLGRPKDQ-EL
AqueK121_Aque_ERK5                 IFP------G-KN-----------------------YVN---QLQLVLSVVGTPSDE-YI
AqueK122_Aque_ERK7                 ------------------------------------------------------------
AqueK123_Aque_ERK7                 x----------xx-----------------------xxx---xxxxxxxxxxxxxxx-xx
AqueK124_Aque_ERK7                 LYP------G-SS-----------------------TIN---QLDRIMSTLPPPSRQ-DM
AqueK125_Aque_ERK7                 LYP------G-SS-----------------------TIN---Q-----------------
AqueK126_Aque_ERK7                 LYP------G-SS-----------------------TIN---QLDRIMSTLPPPSRQ-DV
AqueK127_Aque_JNK                  LLP------G-RD-----------------------YID---QWNKVTQILGTPPQE-FF
AqueK128_Aque_nmo                  LFK------G-SD-----------------------ADS---QLDLILELLGTPSAP-DI
AqueK129_Aque_p38                  LFP------G-SD-----------------------HID---QLTKILQIVGTPDQE-FV
AqueK130_Aque_p38                  LFF------G-KN-----------------------YRD---HLNTILQICGTPDEE-MM
AqueK131_Aque_p38                  LFP------G-DN-----------------------QID---QLHKIFEIMGTPSQS-LI
ERK-p2-2_Smoe_ERK1                 LFP------G-RD-----------------------YVQ---QLRLITELIGSPEDA-DL
ERK-Un_Smoe_ERK1                   I-----------------------------------TIL---NLDVIFNVIGTPGWS-DI
ERK5_b_Smoe_ERK1                   LFP------G-KN-----------------------VTH---QLELITDLLGTPSQD-VI
ERK-p1_a-2_Smoe_ERK1               IFP------G-KN-----------------------YIN---QLKLIIDVIGSPKES-QL
ERK5_a-2_Smoe_ERK1                 LFP------G-KN-----------------------VVH---QLDLMTDMLGTPSAE-SV
ERK-p1_b-1_Smoe_ERK1               IFP------G-KD-----------------------YIH---QLKLIINTIGSPEED-DL
ERK7_Smoe_ERK1                     VFP------G-AS-----------------------TMN---QIEKVLDLIGKPASE-DI
ERK5_a-1_Smoe_ERK1                 LFP------G-KN-----------------------VVH---QLDLMTDMLGTPSAE-SV
ERK5_c_Smoe_ERK1                   LFP------G-KN-----------------------VTH---QLELITDLLGTPSQD-VI
ERK-p2-1_Smoe_ERK1                 LFP------G-RD-----------------------YVQ---QLRLITELIGSPEDA-DL
ERK-p1_a-1_Smoe_ERK1               IFP------G-KN-----------------------YIN---QLKLIIDVIGSPKES-QL
ERK-p1_b-2_Smoe_ERK1               IFP------G-KD-----------------------YIH---QLKLIINTIGSPEED-DL
GK037_Glam_ERK1                    LFP------G-RD-----------------------YIH---QLHLILEVLGTPEKE-LL
GK038_Glam_ERK7                    MFP------G-SS-----------------------TMN---QLDKIMEVTGRPTPE-DI


p38g_Hsap_p38                      QRLQSDEA------------------------KNYM-K---GLPEL-E---KK-DFASI-
p38d_Hsap_p38                      QKLNDKAA------------------------KSYI-Q---SLPQT-P---RK-DFTQL-
p38b_Hsap_p38                      AKISSEHA------------------------RTYI-Q---SLPPM-P---QK-DLSSI-
p38a_Hsap_p38                      KKISSESA------------------------RNYI-Q---SLTQM-P---KM-NFANV-
NLK_Hsap_nmo                       RTAC-EGA------------------------KAHI-L---RGPHK-Q-P-SLPVLYTL-
JNK3_Hsap_JNK                      KKLQ-PTV------------------------RNYV-E---NRPKY-A---GL-TFPKL-
JNK2_Hsap_JNK                      KKLQ-PTV------------------------RNYV-E---NRPKY-P---GI-KFEEL-
JNK1_Hsap_JNK                      KKLQ-PTV------------------------RTYV-E---NRPKY-A---GY-SFEKL-
Erk7_Hsap_ERK7                     LALGSGCR------------------------ASVL-HQL---GSR-P---RQ-TLDAL-
Erk5_Hsap_ERK5                     QAVGAERV------------------------RAYI-Q---SLPPR-Q---PV-PWETV-
nmo_Dmel_nmo                       RHAC-EGA------------------------RTHM-L---RRAPK-P-P-SFSVLYTL-
CG2309_Dmel_ERK7                   ASIGPSFG------------------------SVLLSRNI---QRD-R---RY-SLDEM-
P38c_Dmel_p38                      TGISMERS------------------------RNYL-E---GYPLR-Q---RC-DFHHL-
Mpk2_Dmel_p38                      KKISSESA------------------------RSYI-Q---SLPPM-K---GR-SFKNV-
p38b_Dmel_p38                      SRISSESA------------------------RNYI-R---SLPVM-P---RR-NFRDI-
bsk_Dmel_JNK                       QRLQ-PTV------------------------RNYV-E---NRPRY-T---GY-SFDRL-
rl_Dmel_ERK1                       ECIINEKA------------------------RNYL-E---SLPFK-P---NV-PWAKL-
p38g_Mmus_p38                      QKLQSAEA------------------------KNYM-E---GLPEL-E---KK-DFASV-
p38d_Mmus_p38                      QKLKDKAA------------------------KSYI-Q---SLPQS-P---KK-DFTQL-
p38b_Mmus_p38                      AKISSEHA------------------------RTYI-Q---SLPPM-P---QK-DLSSV-
p38a_Mmus_p38                      NRMPSHEA------------------------RNYI-Q---SLAQM-P---KM-NFANV-
NLK_Mmus_nmo                       RTAC-EGA------------------------KAHI-L---RGPHK-Q-P-SLPVLYTL-
JNK3_Mmus_JNK                      KKLQ-PTV------------------------RNYV-E---NRPKY-A---GL-TFPKL-
JNK2_Mmus_JNK                      KKLQ-PTV------------------------RNYV-E---NRPKY-P---GI-KFEEL-
JNK1_Mmus_JNK                      KKLQ-PTV------------------------RTYV-E---NRPKY-A---GY-SFEKL-
ERK7_Mmus_ERK7                     QDLGSDYS------------------------ALIL-QNL---GSR-P---QQ-TLDAL-
ERK5_Mmus_ERK5                     QAVGAERV------------------------RAYI-Q---SLPPR-Q---PV-PWETV-
ERK4_Mmus_ERK3                     EELLR-VM------------------------PSFV-S---S-TWE-V---KR-PLRKL-
ERK3_Mmus_ERK3                     QELLS-VI------------------------PVYI-R---NDMTE-P---HR-PLTQL-
ERK2_Mmus_ERK1                     NCIINLKA------------------------RNYL-L---SLPHK-N---KV-PWNRL-
ERK1_Mmus_ERK1                     NCIINMKA------------------------RNYL-Q---SLPSK-T---KV-AWAKL-
pmk-3_Cele_p38                     TKIENDNS--SAI-------------------KAVI-QSY---TTH-K---RR-NFRDV-
pmk-2_Cele_p38                     SKIQSEEA------------------------RNYI-K---NRSPI-I---RQ-DFVTL-
pmk-1_Cele_p38                     KKISSEEA------------------------RNYI-R---NLPKM-T---RR-DFKRL-
mpk-1_Cele_ERK1                    QCIINDKA------------------------RSYL-I---SLPHK-P---KQ-PWARL-
lit-1_Cele_nmo                     KYAC-EGA------------------------KNHV-L---RAGLR-A-P-DTQRLYKIA
jnk-1_Cele_JNK                     ERLQ-PTV------------------------RNYV-E---NRPRY-Q---AT-PFEVL-
F09C12.2_Cele_MAPK-Unclassified    RRIKSPSI------------------------RDYI-S---SFGPK-T---PL-PFTAM-
C49C3.10_Cele_JNK                  SQM-NEHA------------------------RNFL-L---RYNLD-QYQAPI-NFYSR-
C05D10.2_Cele_ERK7                 ASIGSHYA------------------------ASVL-EKM---PQR-P---RK-PLDLI-
C04G6.1_Cele_MAPK-Unclassified     NRITSDLV------------------------RDSI-E---ACGRK-T---PL-PFSAI-
SMK1_Scer_ERK1                     IKFGTIKA------------------------WNLG-KN-SNNPVY-K---KI-PWSNI-
SLT2_Scer_ERK1                     RRIGSKNV------------------------QDYI-H---QLGFI-P---KV-PFVNL-
KSS1_Scer_ERK1                     NQIKSKRA------------------------KEYI-A---NLPMR-P---PL-PWETV-
HOG1_Scer_p38                      NTICSENT------------------------LKFV-T---SLPHR-D---PI-PFSER-
FUS3_Scer_ERK1                     RCIESPRA------------------------REYI-K---SLPMY-P---AA-PLEKM-
Erk4_Hsap_ERK3                     DELLR-VM------------------------PSFV-S---S-TWE-V---KR-PLRKL-
Erk3_Hsap_ERK3                     QELLS-VI------------------------PVYI-R---NDMTE-P---HK-PLTQL-
Erk2_Hsap_ERK1                     NCIINLKA------------------------RNYL-L---SLPHK-N---KV-PWNRL-
Erk1_Hsap_ERK1                     NCIINMKA------------------------RNYL-Q---SLPSK-T---KV-AWAKL-
T07A9.3_Cele_JNK                   SQLG-QSA------------------------AMYV-R---SLPRH-Q---AR-AFSEI-
W06B3.2_Cele_MAPK-Unclassified     NEVRCDRT------------------------RKLI-Q---DFGRK-A---DA-EWDDI-
Y51B9A.9_Cele_JNK                  MQM-PDSA------------------------RTFF-L---GLPMN-QYQKPT-NIHEH-
ZC416.4_Cele_JNK                   NQLE-PIG------------------------AVYV-R---SLPQH-L---AR-AFNEI-
YKL161C_Scer_ERK1                  QEIASQKV------------------------YNYI-F---QFGNI-P---GR-SFESI-
Erk1_Ddis_ERK                      CNIANEQA------------------------RQFI-R---NMGNQ-P---KV-NFANM-
Erk2_Ddis_ERK7                     EAIKSPFA------------------------GTML-ESL---PPS-N---PR-SLSDM-
13785_Tthe_ERK                     LQYQD--YKGL------------------------Y-Q---YIIKY-S---KK-SWQDV-
18504_Tthe_ERK                     NNIPREKF------------------------RKMV-K---NMPKR-Q---PK-QFEKL-
18512_Tthe_ERK                     QMIPYDEY------------------------RKFI-R---ELPKR-E---PK-QFEKI-
18725_Tthe_ERK                     AYIGNQDA------------------------IKYI-K---SQPKR-T---KQ-SWQSL-
23186_Tthe_ERK                     ENIQSDRA------------------------KQFI-I---SLGNK-A---PK-DLSKL-
4173_Tthe_ERK                      SYKVDENL------------------------KEYI-K---QLQEK-Q---PE-NFYEI-
6784_Tthe_ERK                      SYITNEGA------------------------LKYL-K---SLPKR-T---KQ-SWENL-
28107_Tthe_ERK                     K---DPEY------------------------KKLL-S---YFPYC-P---GK-NFKLI-
27541_Tthe_ERK7                    EAIESSLA------------------------WNIL-NSI---NIT-K---QK-KFEQF-
28942_Tthe_ERK7                    ESLESQLA------------------------WNII-SSI---NVQ-K---KK-TFHQM-
3210_Tthe_ERK7                     EAIQSDLA------------------------ITML-EAVQNNPTQ-N---TK-TLQQM-
11145_Tthe_MAPK-Unclassified       SFIEKASA------------------------VKFV-R---GFKCK-P---LY-HFTQL-
16370_Tthe_MAPK-Unclassified       DFVTDAKA------------------------IEYL-K---SFKQK-K---RV-DFKDL-
23757_Tthe_ERK                     QFIGNSNA------------------------KQFV-NTL---AKK-N---SV-KVSSF-
13784_Tthe_ERK                     DLLLEKGYKQQ---------------------YNEL-L---SLPFY-R---KQ-PWQVV-
17883_Tthe_ERK                     SQYKDY-TEQY----------------------EQL-K---SLNQY-C---KK-SWQDQ-
ERK5_Spur_ERK5                     KSTSSDHL------------------------YNFF-Q--KNFANK-T---PK-DLSKL-
ERK3_Spur_ERK3                     NEILCTLP------------------------SKLL-K---NYNGY-P---RH-PLKEV-
ERK1_Spur_ERK1                     KCIINEKA------------------------RAYL-Q---GLPFK-S---KI-PLKSL-
ERK7_Spur_ERK7                     ------------------------------------------------------------
JNK_Spur_JNK                       SRLQ-PMV------------------------KQYV-E---NRTKC-P---GY-SFEML-
NLK_Spur_nmo                       KYAC-DGA------------------------RAHL-L---RMPHK-P-P-CLSALYGL-
p38_Spur_p38                       QKIASESA------------------------KTYL-M---SMAAY-P---KR-DFSTI-
CC1G_02007_Ccin_ERK1               RRVGSPRA------------------------QDYI-R---SLPIR-P---RI-SFSTL-
CC1G_14865_Ccin_MAPK-Unclassified  QKIGSDKA------------------------QAYV-R---SLPFR-R---TV-PFRRV-
CC1G_03633_Ccin_MAPK-Unclassified  YAITSRRS------------------------RDYI-R---ALPIR-K---KR-PFPTL-
CC1G_07620_Ccin_MAPK-Unclassified  YAITTRRS------------------------RDYI-R---ALPFR-K---RK-PFSQL-
CC1G_00577_Ccin_MAPK-Unclassified  ETICSENT------------------------LRFV-Q---SLPKR-Q---RV-PFSQK-
AqueK118_Aque_ERK1                 SCIRNEKA------------------------KSYL-K---NLPFK-P---TV-PWSRL-
AqueK119_Aque_ERK1                 AFVKGDAS------------------------RTAL-T---SVQN--S---SP-TFEER-
AqueK120_Aque_ERK1                 AFVTSRIG------------------------LQVL-K---ELKIN-E---SP-SLDSN-
AqueK121_Aque_ERK5                 NNIGSERV------------------------KTYL-K---SLPKK-Q---PV-DLFVL-
AqueK122_Aque_ERK7                 ------------------------------------------------------------
AqueK123_Aque_ERK7                 xxxxxxxx--xxxxxxPPCCGIDVQSIKSPYAKAIL-DQI---IHK-R---HK-YLTDI-
AqueK124_Aque_ERK7                 ESIKSPYA------------------------KAIL-DQI---IHK-R---HK-YLTDI-
AqueK125_Aque_ERK7                 ------------------------------------------------------------
AqueK126_Aque_ERK7                 ESIKSPYA------------------------KAIL-DQI---IHK-R---HK-YLTDI-
AqueK127_Aque_JNK                  KQLQ-PSV------------------------RMYC-E---SQPRH-K---GK-SWNEL-
AqueK128_Aque_nmo                  SHISSPVS------------------------RKRL-L---SVTRP-N-T-MQEVLYQL-
AqueK129_Aque_p38                  TKITSDTA------------------------RSYI-E---SLPKY-P---KK-DFHTF-
AqueK130_Aque_p38                  SKIDSDDA------------------------RTYI-R---SLPTF-A---KK-NFKEY-
AqueK131_Aque_p38                  DKIPHQKT------------------------KLYL-Q---SLKVI-K---PK-NLKNL-
ERK-p2-2_Smoe_ERK1                 GFLRNDNA------------------------RRYV-R---QLQRY-P---RQ-SFAHR-
ERK-Un_Smoe_ERK1                   ESVPSESW------------------------RSYL-K---HLPGR-V---RN-LTEQL-
ERK5_b_Smoe_ERK1                   SRVRNEKA------------------------RRYL-S---TMSKK-S---PV-PFSEK-
ERK-p1_a-2_Smoe_ERK1               GFISNHKA------------------------RSYI-R---SLPPT-P---RV-PLSRL-
ERK5_a-2_Smoe_ERK1                 ARVRNEKA------------------------RRYL-S---GMRKK-T---AI-PFTQK-
ERK-p1_b-1_Smoe_ERK1               QFILSNKA------------------------RSYI-R---SLPFA-P---KI-PLERL-
ERK7_Smoe_ERK1                     AAFESPFA------------------------AAMI-ENM---AITGP---SR-SFRKA-
ERK5_a-1_Smoe_ERK1                 ARVRNEKA------------------------RRYL-S---GMRKK-T---AI-PFTQK-
ERK5_c_Smoe_ERK1                   SRVRNEKA------------------------RRYL-S---TMSKK-S---PV-PFSEK-
ERK-p2-1_Smoe_ERK1                 GFLRNDNA------------------------RRYV-R---QLQRY-P---RQ-SFAHR-
ERK-p1_a-1_Smoe_ERK1               GFISNHKA------------------------RSYI-R---SLPPT-P---RV-PLSRL-
ERK-p1_b-2_Smoe_ERK1               QFILSNKA------------------------RSYI-R---SLPFA-P---KI-PLERL-
GK037_Glam_ERK1                    DRIASDSA------------------------KSYV-L---ALKPS-A---PQ-DLSQK-
GK038_Glam_ERK7                    EATESPFA------------------------SMML-DSL---QPK-T---GK-ALSEI-


p38g_Hsap_p38                      L-----------T-N----------------------AS--PLAVNLLEKMLVLDAEQRV
p38d_Hsap_p38                      F-----------P-R----------------------AS--PQAADLLEKMLELDVDKRL
p38b_Hsap_p38                      F-----------R-G----------------------AN--PLAIDLLGRMLVLDSDQRV
p38a_Hsap_p38                      F-----------I-G----------------------AN--PLAVDLLEKMLVLDSDKRI
NLK_Hsap_nmo                       S-----------S-Q----------------------AT--HEAVHLLCRMLVFDPSKRI
JNK3_Hsap_JNK                      F-----------P-DSLF-------PA-DS--EHNKLKA--SQARDLLSKMLVIDPAKRI
JNK2_Hsap_JNK                      F-----------P-DWIF-------PS-ES--ERDKIKT--SQARDLLSKMLVIDPDKRI
JNK1_Hsap_JNK                      F-----------P-DVLF-------PA-DS--EHNKLKA--SQARDLLSKMLVIDASKRI
Erk7_Hsap_ERK7                     L-----------PPD----------------------TS--PEALDLLRRLLVFAPDKRL
Erk5_Hsap_ERK5                     Y-----------P-G----------------------AD--RQALSLLGRMLRFEPSARI
nmo_Dmel_nmo                       S-----------S-H----------------------AT--HEAVHLLCQMLVFDPDKRI
CG2309_Dmel_ERK7                   M-----------K-N----------------------CC--DDGISLVKALLVLNPHNRL
P38c_Dmel_p38                      F-----------M-G----------------------YD--VQAIDLMEKMLEMVPEKRI
Mpk2_Dmel_p38                      F-----------K-N----------------------AN--PLAIDLLEKMLELDAEKRI
p38b_Dmel_p38                      F-----------R-G----------------------AN--PLAIDLLEKMLELDADKRI
bsk_Dmel_JNK                       F-----------P-DGLF-------PN-DN-NQNSRRKA--SDARNLLSKMLVIDPEQRI
rl_Dmel_ERK1                       F-----------P-N----------------------AD--ALALDLLGKMLTFNPHKRI
p38g_Mmus_p38                      L-----------T-N----------------------AS--PQAVNLLERMLVLDAEQRV
p38d_Mmus_p38                      F-----------P-R----------------------AS--PQAADLLDKMLELDVDKRL
p38b_Mmus_p38                      F-----------H-G----------------------AN--PLAIDLLGRMLVLDSDQRV
p38a_Mmus_p38                      F-----------I-G----------------------AN--PLAVDLLEKMLVLDSDKRI
NLK_Mmus_nmo                       S-----------S-Q----------------------AT--HEAVHLLCRMLVFDPSKRI
JNK3_Mmus_JNK                      F-----------P-DSLF-------PA-DS--EHNKLKA--SQARDLLSKMLVIDPAKRI
JNK2_Mmus_JNK                      F-----------P-DWIF-------PS-ES--ERDKIKT--SQARDLLSKMLVIDPDKRI
JNK1_Mmus_JNK                      F-----------P-DVLF-------PA-DS--EHNKLKA--SQARDLLSKMLVIDASKRI
ERK7_Mmus_ERK7                     L-----------PPD----------------------TP--PEALDLLKRLLAFAPDKRL
ERK5_Mmus_ERK5                     Y-----------P-G----------------------AD--RQALSLLGRMLRFEPSARI
ERK4_Mmus_ERK3                     L-----------P-D----------------------VN--SEAIDFLEKILTFNPMDRL
ERK3_Mmus_ERK3                     L-----------P-G----------------------IS--REALDFLEQILTFSPMDRL
ERK2_Mmus_ERK1                     F-----------P-N----------------------AD--SKALDLLDKMLTFNPHKRI
ERK1_Mmus_ERK1                     F-----------P-K----------------------SD--SKALDLLDRMLTFNPNKRI
pmk-3_Cele_p38                     F-----------S-A----------------------HNPSEDFIDLLEKLLVLDPEKRI
pmk-2_Cele_p38                     F-----------P-M----------------------AS--PYALELLEMMLILDPDRRI
pmk-1_Cele_p38                     F-----------A-Q----------------------AT--PQAIDLLEKMLHLDPDRRP
mpk-1_Cele_ERK1                    Y-----------P-G----------------------AD--PRALDLLDKMLTFNPHNRI
lit-1_Cele_nmo                     S-P---------D-D----------------------KN--HEAVDLLQKLLHFDPDKRI
jnk-1_Cele_JNK                     F-----------S-DNMF-------PM-TA--DSSRLTG--AQARDLLSRMLVIDPERRI
F09C12.2_Cele_MAPK-Unclassified    F-----------P-N----------------------AS--IEARNIVSKMLQISPWKRF
C49C3.10_Cele_JNK                  F-----------P-DTVFQGVLQFEP----------KEC--DMSRDLLFRMLVINPDDRL
C05D10.2_Cele_ERK7                 I-----------T-Q----------------------SQ--TAAIDMVQRLLIFAPQKRL
C04G6.1_Cele_MAPK-Unclassified     F-----------P-K----------------------AS--PEARNMVSYLLQISPWKRY
SMK1_Scer_ERK1                     F-----------P-F----------------------AS--HEAINLIESLLHWDSTHRL
SLT2_Scer_ERK1                     Y-----------P-N----------------------AN--SQALDLLEQMLAFDPQKRI
KSS1_Scer_ERK1                     W-----------S-KT--------------------DLN--PDMIDLLDKMLQFNPDKRI
HOG1_Scer_p38                      F-----------K-T----------------------VE--PDAVDLLEKMLVFDPKKRI
FUS3_Scer_ERK1                     F-----------P-R----------------------VN--PKGIDLLQRMLVFDPAKRI
Erk4_Hsap_ERK3                     L-----------P-E----------------------VN--SEAIDFLEKILTFNPMDRL
Erk3_Hsap_ERK3                     L-----------P-G----------------------IS--REALDFLEQILTFSPMDRL
Erk2_Hsap_ERK1                     F-----------P-N----------------------AD--SKALDLLDKMLTFNPHKRI
Erk1_Hsap_ERK1                     F-----------P-K----------------------SD--SKALDLLDRMLTFNPNKRI
T07A9.3_Cele_JNK                   V-----------P-DTNFL------PETE--NPRVHLTP--HVARDLLFNMLKINPEERY
W06B3.2_Cele_MAPK-Unclassified     M-FCKARGDDQIV-R----------------------GN--CDTIDFVKQLFQYDAQKRI
Y51B9A.9_Cele_JNK                  F-----------P-NSLFLDTMISEP----------IDC--DLARDLLFRMLVINPDDRI
ZC416.4_Cele_JNK                   V-----------P-DSNFL------PETE--NPKDHLTL--HMARDLLFNMLKINPEERY
YKL161C_Scer_ERK1                  L-----------P-G----------------------AN--PEALELLKKMLEFDPKKRI
Erk1_Ddis_ERK                      F-----------P-K----------------------AN--PDAIDLLERMLYFDPSKRL
Erk2_Ddis_ERK7                     Y-----------P-S----------------------AS--VDALDLLKKLLQFNPDKRI
13785_Tthe_ERK                     F-----------P-D----------------------AN--PLLCDLLDKMLVFNEDKRY
18504_Tthe_ERK                     F-----------S-K----------------------AS--KEAIDLLRKLLTFDFTKRI
18512_Tthe_ERK                     F-----------S-K----------------------AP--KEALDLLKKMLTFDFNKRI
18725_Tthe_ERK                     Y-----------P-K----------------------AN--PLALDLLSKMLTFNPEKRY
23186_Tthe_ERK                     I-----------P-N----------------------AS--PQAIDLISKMIVFNPDKRI
4173_Tthe_ERK                      Y-----------K-S----------------------HD--PLAIDLLYKMLAFDPKERW
6784_Tthe_ERK                      Y-----------P-N----------------------AN--LVGLDLLSKMLTFNPNDRY
28107_Tthe_ERK                     F-----------P-N----------------------AS--SQCLDLLKKLLQIDPSQRI
27541_Tthe_ERK7                    F-----------Q-G----------------------AS--PDALDLLKKLLVFNPKLRL
28942_Tthe_ERK7                    F-----------P-G----------------------AS--EEAIDLIKKLLCFNPKNRL
3210_Tthe_ERK7                     I-----------P-M----------------------AS--DDALDLLQNLLQFNPKKRI
11145_Tthe_MAPK-Unclassified       Y-----------Y-S----------------------TV--YQEQFILQSTLQFSPNRRI
16370_Tthe_MAPK-Unclassified       F-----------P-A----------------------AT--PECIDFLNKTLVFNPRKRI
23757_Tthe_ERK                     I-----------N-Y----------------------EN--PLALDLIDKMLAINPSKRI
13784_Tthe_ERK                     F-----------R-R----------------------EN--PLLYDLLDKMLVFNEDKRY
17883_Tthe_ERK                     F-----------P-N----------------------AN--PLLCDLLDKMLVFNEDKRF
ERK5_Spur_ERK5                     Y-----------P-K----------------------AD--PQGLDLLAKMLIFEPSERI
ERK3_Spur_ERK3                     L-----------C-N----------------------LD--CHALDLLLAMLTFDPSERI
ERK1_Spur_ERK1                     F-----------P-K----------------------AD--NKALDFLERMLSFNPDKRI
ERK7_Spur_ERK7                     ------------------------------------------------------------
JNK_Spur_JNK                       F-----------P-DELF-------YQAESSTEKTKLCV--AQARNLLSKMLIVDPEQRI
NLK_Spur_nmo                       S-----------S-H----------------------AT--HEAVHLLSRMLVFNPDKRI
p38_Spur_p38                       F-----------L-G----------------------AS--RKAVDLLEKMLQLDEDRRL
CC1G_02007_Ccin_ERK1               F-----------P-Q----------------------AN--PLAIDLLSRMLCFDPARRI
CC1G_14865_Ccin_MAPK-Unclassified  L-----------P-G----------------------SD--PLALDLMAKMLSFDPSTRV
CC1G_03633_Ccin_MAPK-Unclassified  F-----------P-H----------------------AS--QEAIDFLTKTLTFDPKKRM
CC1G_07620_Ccin_MAPK-Unclassified  F-----------P-N----------------------AN--PLAVDFLTRTLTFDPKKRI
CC1G_00577_Ccin_MAPK-Unclassified  L-----------R-T----------------------TD--PDALDLLERMLVFDPRKRI
AqueK118_Aque_ERK1                 Y-----------P-K----------------------AD--PKALDILGKMLTFNPDERI
AqueK119_Aque_ERK1                 F-----------K-N----------------------ID--PVARDLLKKMLVFNPSQRI
AqueK120_Aque_ERK1                 LRK---------R-N----------------------VD--GQVIDLLKKMLAFSPAKRI
AqueK121_Aque_ERK5                 F-----------P-K----------------------AN--KVALELLEKLLQLDPRKRY
AqueK122_Aque_ERK7                 ------------------------------------------------------------
AqueK123_Aque_ERK7                 L-----------P-Q----------------------AD--DISLDLLNKLLNFNRNKRL
AqueK124_Aque_ERK7                 L-----------P-Q----------------------AD--DISLDLLNKLLNFNPNKRL
AqueK125_Aque_ERK7                 ------------------------------------------------------------
AqueK126_Aque_ERK7                 L-----------P-Q----------------------AD--DISLDLLNKLLNFNPNKRL
AqueK127_Aque_JNK                  F-----------P-DDVF-------PN-DS--KEDAHKT--RLAVDLLTKMLQIEPTRRV
AqueK128_Aque_nmo                  S-----------P-N----------------------AS--HGVVHLLSRMLVFNPYKRI
AqueK129_Aque_p38                  F-----------Q-G----------------------AN--PLAIDLLQMLLTIDPDKRI
AqueK130_Aque_p38                  F-----------T-G----------------------AN--PLAVDLLEKLLHLDPDRRP
AqueK131_Aque_p38                  L-----------E-I----------------------HN--NDALDLLKKLLTLDPERRI
ERK-p2-2_Smoe_ERK1                 F-----------P-N----------------------VP--PLAVDLVERMLVFNPQNRI
ERK-Un_Smoe_ERK1                   L-----------G-----------------------YVD--QEALDLLFRMLAFNPGRRC
ERK5_b_Smoe_ERK1                   F-----------K-N----------------------ID--PLARNLLQKMLAFDPKDRP
ERK-p1_a-2_Smoe_ERK1               Y-----------P-H----------------------AN--PQALQLIERMLAFDPKERI
ERK5_a-2_Smoe_ERK1                 F-----------P-N----------------------AD--PLALRLLERLLAFDPKDRP
ERK-p1_b-1_Smoe_ERK1               Y-----------P-R----------------------AN--PLALNLIDQMLVFDPKKRL
ERK7_Smoe_ERK1                     F-----------P-S----------------------AT--PEAADLLRKLLHFNPQKRL
ERK5_a-1_Smoe_ERK1                 F-----------P-N----------------------AD--PLALRLLERLLAFDPKDRP
ERK5_c_Smoe_ERK1                   F-----------K-N----------------------ID--PLARNLLQKMLAFDPKDRP
ERK-p2-1_Smoe_ERK1                 F-----------P-N----------------------VP--PLAVDLVERMLVFNPQNRI
ERK-p1_a-1_Smoe_ERK1               Y-----------P-H----------------------AN--PQALQLIERMLAFDPKERI
ERK-p1_b-2_Smoe_ERK1               Y-----------P-R----------------------AN--PLALNLIDQMLVFDPKKRL
GK037_Glam_ERK1                    F-----------P-M----------------------LD--EAGIDLLTRMLTLDPLKRI
GK038_Glam_ERK7                    Y-----------P-N----------------------AP--ADALDLLKKLLQFNPNKRL


p38g_Hsap_p38                      TAGE-------------------ALAHPYF
p38d_Hsap_p38                      TAAQ-------------------ALTHPFF
p38b_Hsap_p38                      SAAE-------------------ALAHAYF
p38a_Hsap_p38                      TAAQ-------------------ALAHAYF
NLK_Hsap_nmo                       SAKD-------------------ALAHPYL
JNK3_Hsap_JNK                      SVDD-------------------ALQHPYI
JNK2_Hsap_JNK                      SVDE-------------------ALRHPYI
JNK1_Hsap_JNK                      SVDE-------------------ALQHPYI
Erk7_Hsap_ERK7                     SATQ-------------------ALQHPYV
Erk5_Hsap_ERK5                     SAAA-------------------ALRHPFL
nmo_Dmel_nmo                       SVTD-------------------ALAHPYL
CG2309_Dmel_ERK7                   TAKE-------------------AIRHPYV
P38c_Dmel_p38                      TAAE-------------------AMLHPYL
Mpk2_Dmel_p38                      TAEE-------------------ALSHPYL
p38b_Dmel_p38                      TAEQ-------------------ALAHPYM
bsk_Dmel_JNK                       SVDE-------------------ALKHEYI
rl_Dmel_ERK1                       PVEE-------------------ALAHPYL
p38g_Mmus_p38                      TAAE-------------------ALTHPYF
p38d_Mmus_p38                      TAAQ-------------------ALAHPFF
p38b_Mmus_p38                      SAAE-------------------ALAHAYF
p38a_Mmus_p38                      TAAQ-------------------ALAHAYF
NLK_Mmus_nmo                       SAKD-------------------ALAHPYL
JNK3_Mmus_JNK                      SVDD-------------------ALQHPYI
JNK2_Mmus_JNK                      SVDE-------------------ALRHPYI
JNK1_Mmus_JNK                      SVDE-------------------ALQHPYI
ERK7_Mmus_ERK7                     SAEQ-------------------ALQHPYV
ERK5_Mmus_ERK5                     SAAA-------------------ALRHPFL
ERK4_Mmus_ERK3                     TAEM-------------------GLQHPYM
ERK3_Mmus_ERK3                     TAEE-------------------ALSHPYM
ERK2_Mmus_ERK1                     EVEQ-------------------ALAHPYL
ERK1_Mmus_ERK1                     TVEE-------------------ALAHPYL
pmk-3_Cele_p38                     TVEE-------------------AIQHPYL
pmk-2_Cele_p38                     SVSS-------------------ALRHDYL
pmk-1_Cele_p38                     TAKE-------------------AMEHEYL
mpk-1_Cele_ERK1                    DIEQ-------------------ALAHPYL
lit-1_Cele_nmo                     SVEE-------------------ALQHRYL
jnk-1_Cele_JNK                     SVDD-------------------ALRHPYV
F09C12.2_Cele_MAPK-Unclassified    SAEQ-------------------LLEEPFV
C49C3.10_Cele_JNK                  NIQM-------------------VLSHPYL
C05D10.2_Cele_ERK7                 TVEQ-------------------CLVHPYV
C04G6.1_Cele_MAPK-Unclassified     SADQ-------------------ILQHPFM
SMK1_Scer_ERK1                     NVEQ-------------------AISHPFL
SLT2_Scer_ERK1                     TVDE-------------------ALEHPYL
KSS1_Scer_ERK1                     SAAE-------------------ALRHPYL
HOG1_Scer_p38                      TAAD-------------------ALAHPYS
FUS3_Scer_ERK1                     TAKE-------------------ALEHPYL
Erk4_Hsap_ERK3                     TAEM-------------------GLQHPYM
Erk3_Hsap_ERK3                     TAEE-------------------ALSHPYM
Erk2_Hsap_ERK1                     EVEQ-------------------ALAHPYL
Erk1_Hsap_ERK1                     TVEE-------------------ALAHPYL
T07A9.3_Cele_JNK                   SVED-------------------ALNHPYV
W06B3.2_Cele_MAPK-Unclassified     NIQD-------------------ALLHPYI
Y51B9A.9_Cele_JNK                  DIQK-------------------ILVHPYL
ZC416.4_Cele_JNK                   SVED-------------------ALNHPYT
YKL161C_Scer_ERK1                  TVED-------------------ALEHPYL
Erk1_Ddis_ERK                      TVEE-------------------ALAHP-Y
Erk2_Ddis_ERK7                     TAEE-------------------ALAHPFV
13785_Tthe_ERK                     TVKE-------------------CLQHPYF
18504_Tthe_ERK                     TVDE-------------------ALSHPYL
18512_Tthe_ERK                     TVEE-------------------ALKHPYL
18725_Tthe_ERK                     TVKE-------------------CIEHPYF
23186_Tthe_ERK                     SAEE-------------------ALKHPFF
4173_Tthe_ERK                      TVEQ-------------------CLYHEYF
6784_Tthe_ERK                      TIEE-------------------CLAHPYF
28107_Tthe_ERK                     TAEQ-------------------ALAHPFF
27541_Tthe_ERK7                    DAEQ-------------------ALQHRYV
28942_Tthe_ERK7                    TVEQ-------------------ALEHPYV
3210_Tthe_ERK7                     TAEQ-------------------ALSHPYV
11145_Tthe_MAPK-Unclassified       TAEQ-------------------LLSTEYF
16370_Tthe_MAPK-Unclassified       TIDA-------------------ALNHPLF
23757_Tthe_ERK                     TADE-------------------ALEHPYF
13784_Tthe_ERK                     TVKE-------------------CLQHPYF
17883_Tthe_ERK                     SLKE-------------------CFLHPYF
ERK5_Spur_ERK5                     TVNK-------------------ALQHPFL
ERK3_Spur_ERK3                     TAEE-------------------ALRSPYF
ERK1_Spur_ERK1                     TVEE-------------------ALAHPYL
ERK7_Spur_ERK7                     -----------------------------S
JNK_Spur_JNK                       SVDE-------------------ALQHPYI
NLK_Spur_nmo                       SCID-------------------ALAHPYL
p38_Spur_p38                       SAEQ-------------------ALQHPYL
CC1G_02007_Ccin_ERK1               SCEE-------------------ALNHPYL
CC1G_14865_Ccin_MAPK-Unclassified  TVLE-------------------SLEHPWL
CC1G_03633_Ccin_MAPK-Unclassified  TVDE-------------------ALEHPYL
CC1G_07620_Ccin_MAPK-Unclassified  TVED-------------------ALAHPYL
CC1G_00577_Ccin_MAPK-Unclassified  NASE-------------------SLAHAYV
AqueK118_Aque_ERK1                 SVDA-------------------ALAHPYL
AqueK119_Aque_ERK1                 TAEK-------------------ALEHEYL
AqueK120_Aque_ERK1                 TAEE-------------------ALKHPYF
AqueK121_Aque_ERK5                 IAIE-------------------ILGHPYL
AqueK122_Aque_ERK7                 -----------------------------V
AqueK123_Aque_ERK7                 TAEN-------------------CLEHPYL
AqueK124_Aque_ERK7                 TAEN-------------------CLEHPYL
AqueK125_Aque_ERK7                 -----------------------------L
AqueK126_Aque_ERK7                 TAEN-------------------CLEHPYL
AqueK127_Aque_JNK                  TVDE-------------------ALKHPYV
AqueK128_Aque_nmo                  SCHD-------------------SLSHPYI
AqueK129_Aque_p38                  TAEQ-------------------ALLHPYM
AqueK130_Aque_p38                  SAAE-------------------ALEHPYF
AqueK131_Aque_p38                  TVEE-------------------ALSHPYL
ERK-p2-2_Smoe_ERK1                 SVTE-------------------ALAHPYL
ERK-Un_Smoe_ERK1                   TAEE-------------------ALSHIYV
ERK5_b_Smoe_ERK1                   SATEVKYSLTSEQVMLTRELDFQALADPYF
ERK-p1_a-2_Smoe_ERK1               TVSE-------------------ALDHPYF
ERK5_a-2_Smoe_ERK1                 TAEE-------------------ALADPYF
ERK-p1_b-1_Smoe_ERK1               TVTD-------------------ALEHPYL
ERK7_Smoe_ERK1                     TAEQ-------------------ALQHPYV
ERK5_a-1_Smoe_ERK1                 TAEE-------------------ALADPYF
ERK5_c_Smoe_ERK1                   SATE-------------------ALADPYF
ERK-p2-1_Smoe_ERK1                 SVTE-------------------ALAHPYL
ERK-p1_a-1_Smoe_ERK1               TVSE-------------------ALDHPYF
ERK-p1_b-2_Smoe_ERK1               TVTD-------------------ALEHPYL
GK037_Glam_ERK1                    TVNE-------------------CLSHPYF
GK038_Glam_ERK7                    TAEQ-------------------ALEHPYL