TSSK4_Hsap YEVGKAIGHGSYGSVYEAFYTKQK----------------VMVAVKIISK--KKASDDYL
TSSK3_Hsap YQLGKTIGEGTYSKVKEAFSKK----------------HQRKVAIKVIDK--MGGPEEFI
TSSK2_Hsap YIVGINLGKGSYAKVKSAYSER----------------LKFNVAVKIIDR--KKTPTDFV
TSSK1_Hsap YLLGINLGEGSYAKVKSAYSER----------------LKFNVAIKIIDR--KKAPADFL
SSTK_Hsap YKLGRTIGEGSYSKVKVATSKK----------------YKGTVAIKVVDR--RRAPPDFV
B0511.4_Cele LKFEKVLGSGSYSRVARATFGEK----------------KLEVAAKIINITPTREKEDYI
CG14305_Dmel YNVGHKIGEGSYATVITAGYADDH-------------GHGVHLACKIIDK--AKAPTDFV
CG9222_Dmel IILGKVIGTGNYAKVKIGFSEEYG----------------KRVAVKIISK--VKAPSEYT
SSTK_Mmus YKLGRTIGEGSYSKVKVATSKK----------------YKGTVAIKVVDR--RRAPPDFV
TSSK1_Mmus YIMGINLGEGSYAKVKSAYSER----------------LKFNVAVKIIDR--KKAPSDFL
TSSK2_Mmus YIVGINLGKGSYAKVKSAYSER----------------LKFNVAVKIIDR--KKTPTDFV
TSSK3_Mmus YQLGKTIGEGTYSKVKEAFSKK----------------HQRKVAIKIIDK--MGGPEEFI
TSSK4_Mmus YEVGKIIGHGSYGTVYEAYYTKQK----------------VMVAVKIISK--KKASEDYL
TSSK5_Mmus LLSSKKIGSGAFSKVYLAYATRERMKHNPRLSSDLRGKRHTMVAIKIVSM--AEAPAEYS
W02B12.12_Cele LDTSNKLGRGKYSKVYKAFDRNN----------------NRVVAVKAIDT--QELTTDVK
Y38H8A.4_Cele LKFDKILGSGSYSRVARATWGDK----------------KLEVAAKVINITPTREKDDYI
TSSK2_Spur YTLGLMLGEGSYAAVYSCQLSN----------------NRGKCAIKIINR--KKAPKDFL
TSSK4_Spur FNVQETVGHGSYAAVKCAYSTKHK----------------CKVAIKVVSK--KKAPEDYL
TSSK6_Spur FCLAHKLGSGSYSKVRMAVHKT----------------TRKRVAVKIIDR--RRAPRDYQ
TSSK3_Spur FNVQGKLGEGTYAKVRRAYSYS----------------EKCRVAIKIVSR--SLNA--FA
TSSK5_Spur -----TLGSGTYAKVKLARAMKRKIAQTAKLRDDLRIKGHNMVAIKIISR--RDAPTEYL
AqueK086_Aque YILGKTLGSGTYAKVKAAWSKRHQ----------------SLVAIKILNK--SVASRDYL
AqueK087_Aque YILQTTIGNGAYAKVKLAHSVSMN----------------KKVAIKIVDK--KKAPHDVL
:* * :. * * * :.
TSSK4_Hsap NKFLPREIQVM-KVL-RHKYLINFYRAIEST-SRVYIILELAQGGDVLEWIQR------Y
TSSK3_Hsap QRFLPRELQIV-RTL-DHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLN------G
TSSK2_Hsap ERFLPREMDIL-ATV-NHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKC------Q
TSSK1_Hsap EKFLPREIEIL-AML-NHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKT------R
SSTK_Hsap NKFLPRELSIL-RGV-RHPHIVHVFEFIEVCNGKLYIVMEAA-ATDLLQAVQR------N
B0511.4_Cele KKFLPREKEIV-KLL-KHDNICRLYEMISFQ-DHIIFVNEYCAGGDLLRKMKD------I
CG14305_Dmel NKFFPRELEIL-TKI-DHSNIIQIHSILQRG-PKIFIFMRYAENGDLLSHIKR------S
CG9222_Dmel QKFLPREIEAV-KGL-HHENLITFYQSIETS-HRVYLIMQLAENGTLLDYVRE------R
SSTK_Mmus NKFLPRELSIL-RGV-RHPHIVHVFEFIEVCNGKLYIVMEAA-ATDLLQAVQR------N
TSSK1_Mmus EKFLPREIEIL-AML-NHRSIVKTYEIFETSDGKVYIVMELGVQGDLLEFIKT------R
TSSK2_Mmus ERFLPREMDIL-ATV-NHRSIIKTYEIFETSDGRIYIVMELGVQGDLLEFIKC------R
TSSK3_Mmus QRFLPRELQIV-RTL-DHKNIIQVYEMLESADGKIYLVMELAEGGDVFDCVLN------G
TSSK4_Mmus NKFLPREIQVM-KVL-RHKYLINFYQAIETT-SRVYIILELAQGGDVLEWIQR------Y
TSSK5_Mmus RKFLPREILSLNATY-KHMNIVQLYETYQNS-QRSYLVLELAARGDLLEHINAVSDLRCC
W02B12.12_Cele MKFLPRELSCW-RKL-KNPFVVGLHAQYEAQ-SMIFLTMEYGSQGDLLRYVQE------H
Y38H8A.4_Cele KKFLPREKEIV-KLL-KHDNVCRLYEMISFP-DHIIFVTEFCAGGDLLRKMKK------I
TSSK2_Spur EKFLPREIKIL-SKV-QHRNIVKCFEIFDTGQGKVYMVLELAGHGDMLEYIKL------R
TSSK4_Spur IKFLPREIQVV-KIL-KHPNLICFLQSIETT-SRVYLIMELADNGDLLDFIKA------N
TSSK6_Spur DHFLPRELAVI-RQL-QHPNVLRTYEWFEQN-QKVYMVLELAESGDVLEYIRTV----TK
TSSK3_Spur E--ISSELKIV-RNM-RHPHIIELLEMFESN-GVIFLIMELARHGDLLEYVQK------K
TSSK5_Spur KKFMPREIDAM-RITHKHAHLIQLYEFFRSE-RGVYLVLEYAAHGDVLSYINDSVQ-ETG
AqueK086_Aque HKFLPREIDIL-QKI-NHSSIIRVLEIIETD-KLAYFMMELAQNGDLLDYINA------R
AqueK087_Aque TKFLPREIDAL-QAMRGHDNIIYLHEVIHTN-DKIFMVMDLADNGDLLDYINS------K
:. * : : : :: :
TSSK4_Hsap GACSEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLDKW-ENVKISDFGFAKMVPSN
TSSK3_Hsap GPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQ-G-FNLKLTDFGFAKVLPK-
TSSK2_Hsap GALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKD-FNIKLSDFGFSKRCLRD
TSSK1_Hsap GALHEDEARKKFHQLSLAIKYCHDLDVVHRDLKCDNLLLDKD-FNIKLSDFSFSKRCLRD
SSTK_Hsap GRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAH--
B0511.4_Cele VAMKEEDAKFTFRQLIAALTHLQSYNIVHRDLKCENIFMDKH-GNVKLGDFGFSRILKP-
CG14305_Dmel GPIDEKQSKIWFFQMSKALKYLHNLDIAHRDLKCENILLSKR-LNIKLADFGFARYCR-D
CG9222_Dmel KFLDEPQSRTLFKQLVSAVEYIHSKGVVHRDIKCENLLLDEN-WNLKLIDFGFARKDTRT
SSTK_Mmus GRIPGSQARELFSQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKITDFGFGRQAH--
TSSK1_Mmus GALQEDDARKKFHQLSSAIKYCHDLDVVHRDLKCENLLLDKD-FNIKLSDFGFSKRCLRD
TSSK2_Mmus GALHEDVARKMFRQLSSAVKYCHDLDVVHRDLKCENLLLDKD-FNIKLSDFGFSKRCLRD
TSSK3_Mmus GPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQ-G-FNLKLTDFGFAKVLPK-
TSSK4_Mmus GACAETLAGKWFSQMALGIAYLHSKGIVHRDLKLENLLLDKR-ENVKISDFGFAKMVPSS
TSSK5_Mmus PGLEEEEARRLFWQLVSAVAHCHNVGIVHRDLKCENILLDDQ-GFIKLTDFGFANWVGL-
W02B12.12_Cele GGIHEQKAGLFMSQLIRGLQFMHSINIAHRDIKLENIILFD-N-CVKLSDFGFVRKMDE-
Y38H8A.4_Cele KTMSEENAKFTFRQFIAALMHLQSYNIVHRDLKCENIFLDKY-ENVKLGDFGFSRILKP-
TSSK2_Spur RSLTEEKARAFFRQMVDGIAYLHSLNAVHRDLKCENILLDAS-NTIKISDFGFARYMEP-
TSSK4_Spur GAGTEEQTGLWFHQLVDGMDYCHNLGVVHRDLKCENLLLNKH-NMLKITDFGFARSKMKP
TSSK6_Spur GAVPEVLARKWSLQTGRALLYMHGMDVVHRDVKCENLLLDRC-NNIKLTDFGFVRSVG--
TSSK3_Spur NALRDSEARTVFSQILSAVEHLHFHGVYHRDLKCENILLDTG-ITAKITDFGFAREWSE-
TSSK5_Spur MAVEEDKARQLFRQIVSGVTFCHDRNVVHRDLKCENIILDEN-WNVKISDFGFACRFPSN
AqueK086_Aque RTLPEAEAKYLFRQLVLGIQYLHRHNIVHRDLKCENIMLSKD-MEVKIGDFGFSLNLS--
AqueK087_Aque KRLSERTARSFFRDMVSAITATHRKDIVHRDIKCENLLLDAN-YRLKISDFGFARSVQE-
: : .: : ***:* :* :: *: **.*
TSSK4_Hsap QPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILR--GLPYNPFLSDTWSMGVILYTLVV
TSSK3_Hsap -------------SHRELSQTFCGSTAYAAPEVLQ--GIPHDSKKGDVWSMGVVLYVMLC
TSSK2_Hsap S-----------NGRIILSKTFCGSAAYAAPEVLQ--SIPYQPKVYDIWSLGVILYIMVC
TSSK1_Hsap D-----------SGRMALSKTFCGSPAYAAPEVLQ--GIPYQPKVYDIWSLGVILYIMVC
SSTK_Hsap -------------GYPDLSTTYCGSAAYASPEVLL--GIPYDPKKYDVWSMGVVLYVMVT
B0511.4_Cele ---------------GEKSGTFCGSRAYVAPEIFR--GREYSGNAVDVWSTGVILYIMLA
CG14305_Dmel D-----------NGREMKSETYCGSAAYAAPEVVC--GRPYDPKLADAWSLGVILFIMMN
CG9222_Dmel S-----------DNQVILSKTFCGSYAYASPEILK--GVAYDPFMSDIWACGVVCYAMVF
SSTK_Mmus -------------GYPDLSTTYCGSAAYASPEVLL--GIPYDPKKYDVWSLGVVLYVMVT
TSSK1_Mmus D-----------SGRLILSKTFCGSAAYAAPEVLQ--GIPYQPKVYDIWSLGVILYIMVC
TSSK2_Mmus G-----------SGRIVLSKTFCGSAAYAAPEVLQ--GIPYQPKVYDIWSLGVILYIMVC
TSSK3_Mmus -------------SRRELSQTFCGSTAYAAPEVLQ--GIPHDSKKGDVWSMGVVLYVMLC
TSSK4_Mmus QPVHSSPSYRQMNSLSHLSQTYCGSFAYACPEILL--GLPYNPFLSDTWSMGVILYTLVV
TSSK5_Mmus --------------KNSLLSTFCGSVAYTAPEILM--SKKYNGEQADLWSLGIILHAMVS
W02B12.12_Cele ---------------SALSSTFCGSKSYSAPELLR--GIVYNPFLSDVWSLGVVGFVMVT
Y38H8A.4_Cele ---------------GEKSGTFCGSRAYVAPEILR--GREYSGNAVDVWSTGVILYIMLV
TSSK2_Spur ---------------KDLSKTYCGSAAYAAPEILK--GNMYNGKLYDVWSLGIILYIMVC
TSSK4_Spur P----------EPGRTILSETYCGSYAYAPPEILR--GIPYCPMLGDIWSMGVILYTMLY
TSSK6_Spur --------------KGSLSKTFCGSAAYAAPEIIR--SVPYCPLKSDVWALGVVIYILVV
TSSK3_Spur ---------------AKPCSTFCGSAAYASPEILQ--AIPYDPNWADIWSLGIILYIMVT
TSSK5_Spur --------------RCNMLSTFCGSYAYAAPEIMA--GKNYDGKLADVWSLGIILYALVN
AqueK086_Aque ---------------TAPSKTPCGSYSYAAPELFQSSGEPYDGRKSDAWSLGVILFAMTC
AqueK087_Aque ---------------GSLLETYCGSFAYAAPEIIR--GEPYSGKKSDVWSMGVVLYAMVC
* *** :* **:. . : * *: *:: . :
TSSK4_Hsap AHLPFDD--TNLKKLLRET--------------QKEVTFPAN--HTISQECKNLILQMLR
TSSK3_Hsap ASLPFDD--TDIPKMLWQQ--------------QKGVSFPTH--LSISADCQDLLKRLLE
TSSK2_Hsap GSMPYDD--SDIRKMLRIQK-------------EHRVDFPRS--KNLTCECKDLIYRMLQ
TSSK1_Hsap GSMPYDD--SNIKKMLRIQK-------------EHRVNFPRS--KHLTGECKDLIYHMLQ
SSTK_Hsap GCMPFDD--SDIAGLPRRQ--------------KRGVLYPEG--LELSERCKALIAELLQ
B0511.4_Cele GSMPFDD--RDPRKMIERQL-------------AHKIKFPKS--CTSSVFSKALVLEILQ
CG14305_Dmel AKMPFDD--SNLTKLLEDQR-------------NRKFAFRRKLQETISAQAKATVSVLLE
CG9222_Dmel GRLPYDG--SNVHILLKRI--------------NQSLVFPKS--PSASSECKHMIMHILA
SSTK_Mmus GCMPFDD--SDIAGLPRRQ--------------KRGVLYPDG--LELSERCKSLIAELLQ
TSSK1_Mmus GSMPYDD--SNIKKMLRIQK-------------EHRVNFPRS--KHLTGECKDLIYRMLQ
TSSK2_Mmus GSMPYDD--SDIKKMLRIQK-------------EHRVDFPRS--KNLTGECKDLIYRILQ
TSSK3_Mmus ASLPFDD--TDIPKMLWQQ--------------QKGVSFPTH--LGISTECQDLLKRLLE
TSSK4_Mmus ARLPFDD--TNLKKLLRET--------------QKEVTFPAN--LTISQECKNLILQLLR
TSSK5_Mmus GKLPFKE--HQPHRMLNLI--------------RRGPIFR--PG--LSPECRDLIRGLLQ
W02B12.12_Cele NRMPFDE--KKPNNVIVELQRYLMTLIQPRSGRNRQYVIPHS--VFLSTSCISSFESMMA
Y38H8A.4_Cele GTMPFDD--RDPTRMIERQL-------------AHKIKFGKT--CTASIHSKALILEILQ
TSSK2_Spur GTMPFDD--SNIKRMIKDQM-------------DQRLCFTKR--KELTLLFKDIVLAILQ
TSSK4_Spur GRLPYDD--TNHKVLLNQV--------------QRPPGFPTS--QVVHSDCKDLMCRILS
TSSK6_Spur GCMPFGDDVKNIKKILHQQ--------------YSGAHFDASKNTAVRDECRDLIRSMLT
TSSK3_Spur GRMPYTE--LEIM-----------------------------------------------
TSSK5_Spur GRLPFND--QNLNTLMDQT--------------KKKIKFQP----WVSKACIHLIRKLLR
AqueK086_Aque GRLPFGD--DSQV--KAQQ--------------KLGLIFPPS--RPLSHDAKDLLRNILS
AqueK087_Aque GKLPFKD--GDFKSLLRQI--------------TAGVSFHS----DVSETCRDLILKILV
:*: .
TSSK4_Hsap Q-ATKRATILDIIKDSWV
TSSK3_Hsap PDMILRPSIEEVSWHPWL
TSSK2_Hsap PDVSQRLHIDEILSHSWL
TSSK1_Hsap PDVNRRLHIDEILSHCWM
SSTK_Hsap FSPSARPSAGQVARNCWL
B0511.4_Cele PHAPNRPTYKAICESEWL
CG14305_Dmel PEAHARWNLREILNCAWL
CG9222_Dmel P-VKIRYNIPQVKEDPWY
SSTK_Mmus FSPSARPSAGQVARNGWL
TSSK1_Mmus PDVNRRLHIDEILNHCWV
TSSK2_Mmus PDVNRRLHIDEILSHSWL
TSSK3_Mmus PDMILRPSIEEVSWHPWL
TSSK4_Mmus Q-STKRATILDVLRDPWM
TSSK5_Mmus LHPCERLDLQQVAAHCWM
W02B12.12_Cele FDTRNRPTSTDCLALPWI
Y38H8A.4_Cele PHAPNRPTYKAICESEWL
TSSK2_Spur PNINMRLKVNDILNHPWM
TSSK4_Spur P-AKRRINMEEIQHNAWY
TSSK6_Spur ISPKARLTLGEVMESEWL
TSSK3_Spur -----------------Q
TSSK5_Spur QRPLLRLHANEIVHHPWV
AqueK086_Aque PKVKDRFDTYDMILHDWT
AqueK087_Aque LSPTERLSTSSILSHAWM