CG7616_Dmel MRP-LQRVRQLL---SLGTRIRG--------KRA--------------------------
ADCK5_Mmus MWRPMRLCHFHSTLLQSRQKPWP--CPAIFFRRNFKSP----------------------
ADCK5_Hsap MWRPVQLCHFHSALLHRRQKPWP--SPAVFFRRNVRGL----------------------
AdckB2_Ddis MKI-LKFSL--------LSKLKHKDFIVTSFRNNIINSIKNNNTNNNGLLKFSNNKYNFL
ADCK5_Spur MEM-ARLCRHMIKNPSALTRVSHS---GSNMRRSLLAL----------------------
AqueK031_Aque MGRYSRVLGF--------------------------------------------------
ABC1-D_b_Smoe MKV----------------SVTP--GGR--WNR---------------------------
ABC1-D_a_Smoe RIT-----KSVLLPLSDRVDVLP--SDENFSWS---------------------------
CG7616_Dmel ----------------------------------------LNGLREA-------------
ADCK5_Mmus ----------------------------------------PART----------------
ADCK5_Hsap ----------------------------------------PPRF----------------
AdckB2_Ddis NNNNNNNNNNVNKINNVYYINNNFKNVMENKIKPSS-IQFFSSLSNKYNLNSFTTTKPQP
ADCK5_Spur ----------------------------RTSIGHASVKRMFSEVKHDI------------
AqueK031_Aque ------------------------------------------------------------
ABC1-D_b_Smoe -------------------------------------FKAYSTL----------------
ABC1-D_a_Smoe -------------------------------------KENYSKL----------------
CG7616_Dmel ---------------------------------NVQKGGRPVLRF---------------
ADCK5_Mmus --------------------------------SRARLLWRRALSAT--------------
ADCK5_Hsap --------------------------------SSPTPLWRKVLSTA--------------
AdckB2_Ddis CQAKPPSSKQQQQQQQQQQQQQQQQQQQQSKKKTSKDRLRDILKKTVITPQEFLNVLQRF
ADCK5_Spur -------------------------------VAEAVKPKRRILRKTF-------------
AqueK031_Aque -----------------------------------------LL-----------------
ABC1-D_b_Smoe --------------------------------QRSLEIWAFVF-----------------
ABC1-D_a_Smoe --------------------------------QRTIDVWSFVL-----------------
:
CG7616_Dmel ---------SLL-AAGAGG-LAYDGI---VNDF--TYCGASVRFVRSLKTAGLIAADYL-
ADCK5_Mmus ----------VVGTPFLLG-AYYFMAEASERRKLRLAVDGIGRFGRSVKIGLFISTDYWW
ADCK5_Hsap ----------VVGAPLLLG-ARYVMAEAREKRRMRLVVDGMGRFGRSLKVGLQISLDYWW
AdckB2_Ddis AKNYKKTIASILAAIALII-YSYETPDSY----FGSMMNVIVRFYRAMKCATKIMINYKI
ADCK5_Spur -------LGLTGIAAVAGG-VTYVSMDSAGRRRAYVTAEGFIRFFRTFYIGTRISLDYKW
AqueK031_Aque ------------GSSAVGGSAYYWSRDDGEKRWLKVQLKGITRFARSAAIGITISCDYWW
ABC1-D_b_Smoe --------S-FLFKQWLLG-R-------------------------------------KF
ABC1-D_a_Smoe --------S-LRAKLFLID-A-------------------------------------KW
CG7616_Dmel -------RLDENDPEYETKVKL-LHKKS-AERLLETCLLNGGLYIKVGQGFAAINDILPV
ADCK5_Mmus CTNVVLRGVEENSPKYVEIMSA-CHQRA-ADTLVAGAIRNGGLYVKLGQGLCSFNHLLPT
ADCK5_Hsap CTNVVLRGVEENSPGYLEVMSA-CHQRA-ADALVAGAISNGGLYVKLGQGLCSFNHLLPP
AdckB2_Ddis -----LSYTPEKSSEYLEKSKI-CHQES-ADLILDLCLTNGGLYIKAGQYIASLNHILPI
ADCK5_Spur N----LWKLEDGSQEYKEAFRA-CNRRT-GDLILKGCLKNGGLYIKLGQYMVTANYILPK
AqueK031_Aque T----MRNLDETDPDYSLSMSA-CHQRA-ADRIVNGAMANGGLYIKLGQGLGSFNQILPR
ABC1-D_b_Smoe M-------YK---GGITEEKKMERRKRL-AKWLKEGLLRLGPTFIKIGQQFSTRSDILPK
ABC1-D_a_Smoe S-------YV---GGFSEEKKI-SRRRSIAVWVKETILQLGPTFIKLGQLFSTRSDLFPA
.:. . : : * ::* ** : : . ::*
CG7616_Dmel EYTSTLSLLQDRCLPTTQADVQKVFRKDFGQLPEEIYQEFDYQPVAAASLAQVFKARLPS
ADCK5_Mmus EYIQTLRVLEDKALTRGFREVDELFLEDFQALPNELFQEFDYEPMAAASLAQVHRAKLHD
ADCK5_Hsap EYTRTLRVLEDRALKRGFQEVDELFLEDFQALPHELFQEFDYQPIAAASLAQVHRAKLHD
AdckB2_Ddis QYTKTLSVLQDQAPWRDFYEVESVFLKDLGNAPNHYFSDFDRLPIAAASLAQVHRAITKE
ADCK5_Spur EILQKLATLQDRALTREYKELDRLFKEEFGKTPDELYAEFDPEPIAAASLAQVHRAKTHE
AqueK031_Aque EYIDTLKILLNKALFRDDKELDQLFKEDFGLKVDNIFAQFDRQPVAAASLAQVYKAMTND
ABC1-D_b_Smoe EYVDELAELQDQVPPFESEAAVSILEEELGCSVDQVFEKFDRDPIAAASLGQVHRAVL-N
ABC1-D_a_Smoe EFVEELAKLQDRVPAFSPEKAELMIENELDTPMQVLFSEFERQPLAAASLGQVHRAVLRN
: * * :: :: ::: . : .*: *:*****.**.:* .
CG7616_Dmel GEQVAVKVQYNDLQKRFISDLGTIIFLQDIVEFFFK-----DYNFGWILNDLRKNLVLEL
ADCK5_Mmus GTDVAVKVQYIDLRDRFDGDVQTLELLLRLVELMHP-----SFGFSWVLQDLKGTLVQEL
ADCK5_Hsap GTSVAVKVQYIDLRDRFDGDIHTLELLLRLVEVMHP-----SFGFSWVLQDLKGTLAQEL
AdckB2_Ddis GEEVAVKVQYVDLQRNFDGDIFTHNVLLTLVNMAFP-----DFEFNWMAEEMKNVLIKEL
ADCK5_Spur GDEVAVKVQYINLRDQYPGDLRTLEILLDIIHWMHPK----SFNFKDILLDLEEPLAKEL
AqueK031_Aque GQSVAVKVQYIDLRDRYHGDIWTIRILLKFIAWMHP-----SFSFSWVLDELKDTLYEEL
ABC1-D_b_Smoe GEQVVIKIQRPGLKALFDIDLKNLRVIAENLQKIDPKSDGAKRDWVAIYDECANVLYQEI
ABC1-D_a_Smoe GEQVVVKIQRPGLKELFDIDLSNLKFIAEYFQKDEM-LGGPLRDWVGIYDECATVLYREI
* .*.:*:* .*: : *: . .: . : : : * *:
CG7616_Dmel NFLQEGQNAERCAKDMEKFSYVHVPKVHWSYTKTRVLTLEWMDGCKISDLKTIEKEKLSL
ADCK5_Mmus DFENEGRNAERCAQELKHFHYVVIPRVHWDRSSKRVLTADFCNGCKVNDMEGIKSQGLAV
ADCK5_Hsap DFENEGRNAERCARELAHFPYVVVPRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGLAV
AdckB2_Ddis DFSQEADNAERAAQDLSSNNNAYIPKVFRPYSSKRILTTEFIHGCKINNVQAIRSMGLSE
ADCK5_Spur DFENEGRNSETCAKQLKHLDYVYVPKVYWNLTNKRILTMEFVKGHKVSEKEKLQEDGFSL
AqueK031_Aque DFEHEGLNQERCARELKHLSYVCVPKIRWEHTSKRVLTSQWIDGCQVTDVQSLRERGLSL
ABC1-D_b_Smoe DYNREAANAERFAANFKDLSYVKVPRIYWKYTTPQVLTMEYVPGIKINKIKALDRLGVDR
ABC1-D_a_Smoe DYINEGRNADKFRRDFRNIKWVKVPKVYWDFTSRKVITLEYLPGIKINDLAALDAGSYKR
:: .*. * : :: . :*:: :. :::* :: * ::.. :
CG7616_Dmel KDIDVKLFEAFAEQIFYTGFVHADPHPGNIFVRKNRK-NGRADIILLDHGLYEELPQNVR
ADCK5_Mmus QDVAKKLIQTFAEQIFHTGFIHSDPHPGNVLVRKGPD--GKAELVLLDHGLYQFLDEKDR
ADCK5_Hsap HDIAEKLIKAFAEQIFYTGFIHSDPHPGNVLVRKGPD--GKAELVLLDHGLYQFLEEKDR
AdckB2_Ddis KTVSQRFMEIMCEQIFIHAFVHVDPHAGNVLVRQHPNHPNQPQIVLLDHGLYREYDEEFR
ADCK5_Spur AEVDEKLIKIFGEQIFHTGFVHADPHPGNVLVRKNGK--GKAELIVLDHGLYEEVTPEIR
AqueK031_Aque AEVAHKVTRAFSEQLFVTGFVHGDPHPGNVLICKSPK-SNSVQVCLLDHGLYTPITEHIR
ABC1-D_b_Smoe QRLARYCVESYLEQILRHGFFHADPHPGNIAVDDFN----GGRLIFYDFGMMGSISSNIR
ABC1-D_a_Smoe SLIASRAIEAYLIQILKTGFFHADPHPGNLAVDV------DGSLIYYDFGMMGEIKSFTK
: . *:: .*.* ***.**: : : *.*: :
CG7616_Dmel GPLCEFWEATVLRQENRMQAAAEKIGIGDYMRFAEVLFQQPIRNRG-GGIRG----KLTQ
ADCK5_Mmus SSLCQLWRAIILRDNAAMKKHAAALGVQDYMLFSEVLMQRPVRLG-QLWGSH----LISR
ADCK5_Hsap AALCQLWRAIILRDDAAMRAHAAALGVQDYLLFAEMLMQRPVRLG-QLWGSH----LLSR
AdckB2_Ddis LNFCNLYKNLVLCNNKKVEKYSKALGVQNWKLFSTMILMRNFEGSS-VGLSN----SISS
ADCK5_Spur IAFGQYWRAIILKNEQAMIQHANELGIEEYLLFAMMLIQRPLNMNA-KRGSHMTF-NLSN
AqueK031_Aque LRLCGIIKSTVQYDVPNLKSYCLELGIEDYELFALMLTGRTLKSHREMFNSS----LLTR
ABC1-D_b_Smoe EGLLEAFYGVYEKDADKVLEAMVQMGVLVPT-----GDMTAVRRTAQFFLKSFQDRLAAQ
ABC1-D_a_Smoe EKLLELFYAVYEEDASKVIQGLVDLGALVPT-----GDMGPVKKTIQFFLKN----LTSQ
: : : :* .. :
CG7616_Dmel EDIDHMQE---------IAR---------------NNFEH-IMGTLKEMPRSMLFVVRNL
ADCK5_Mmus EEAAYMQD---------MAR---------------EHFDG-IMEVLKALPRPMLLVLRNI
ADCK5_Hsap EEAAYMVD---------MAR---------------ERFEA-VMAVLRELPRPMLLVLRNI
AdckB2_Ddis EELEKLLS---------GAI---------------ERLKD-INLLMKAMPRHLLLILRNN
ADCK5_Spur AELRKLQR---------EIRDEMHTMED-----KIEEFQERMNVFMESFPKCL-------
AqueK031_Aque RDVKAVTG---------TFM---------------YRMDD-VVEILRLLPPSMLLVFRNI
ABC1-D_b_Smoe KEQKALAESEESGYKRLSKGEREDKKKLRLAAIGEDLLSI-SSDQPFRFPATFTFVVRAF
ABC1-D_a_Smoe RPDQATTF----------------------TAIGEDLFAI-AVDQPFRFPSTFTFVLRAF
: :* :
CG7616_Dmel NTVRAISHQHGDVVNRPRVMARYAQKCLYMQ------------------------HNRRS
ADCK5_Mmus NTVRAINSNLGTPVDRYFLMAKSAVWGWSRLVGA-----------------AY-QGIYGS
ADCK5_Hsap NTVRAINVALGAPVDRYFLMAKRAVRGWSRLAGA-----------------TY-RGVYGT
AdckB2_Ddis NLLRSINMELGSPVNRFSIMARYAAKGLNSN------------------------SSKNS
ADCK5_Spur ------------------------------------------------------------
AqueK031_Aque NLIRSINRELGIPINRFKVMAKIAIEGYHYE-----------------------KEKQSF
ABC1-D_b_Smoe SVLDGIGKGLDPYFDISEIAKPYALEILRFREVGYDVVIRDFKKRWQRQAEAFNNLFRQP
ABC1-D_a_Smoe STLEGIGYILDPKFSFAKIAAPYAQTR---DA-----------------------TVAMP
CG7616_Dmel -PVQYIRWLS-GRIYFEYCLFLSAFKLY--------------------------------
ADCK5_Mmus SLLRHIKVLW-EALKFEMALRLEILAMR--------------------------------
ADCK5_Hsap SLLRHAKVVW-EMLKFEVALRLETLAMR--------------------------------
AdckB2_Ddis GIIRLVKSVE-EKVSLEVMLKGYELYYY--------------------------------
ADCK5_Spur ------------------------------------------------------------
AqueK031_Aque SVLNSVRRWI-DQRQFDFRLXRKL-QY---------------------------------
ABC1-D_b_Smoe DRVAKLADVIERLEQGDLKLRVRTLESERSFKRVSAVQQNIAQAVFAGTFLNLGTLLYIN
ABC1-D_a_Smoe MRVQHIEKFMQQLEDGDIKLRVRVLEAERAARKSSVLQTTT-------------------
CG7616_Dmel ----------LLDWY--FNILYLVGRAPASARTVMKDIMQPPEPNVLK
ADCK5_Mmus ----------LTALM--LRVLVRLGFAPKA--EAEEV-----YQYLEM
ADCK5_Hsap ----------LTALL--ARALVHLSLVPPA----EEL-----YQYLET
AdckB2_Ddis ----------FVNRI--LSILIRLHIINPE--KLIKD-----QMKKLG
ADCK5_Spur --------------------------------------------FLIF
AqueK031_Aque --------------------------------KSASS-----SAVEKN
ABC1-D_b_Smoe AMRVQGTAAFFCSALFGLKLLVGLFKVKRL--D-----KQEKLITGTV
ABC1-D_a_Smoe --------MNLVAA--A--TLVNVGVTLST--QGLQDFAIASFLGAGK