Protein (view, download) , Domain (view, download)
Cdk8_Dmel        ---EGCKVGRGTYGHVYKAKWKET--S-DGKEYALKQ----------IDGTGLSMSACRE
CDK8_Mmus        FEYEGCKVGRGTYGHVYKAKRKDG--K-DDKDYALKQ----------IEGTGISMSACRE
CDK19_Mmus       FEYEGCKVGRGTYGHVYKARRKDG--K-DEKEYALKQ----------IEGTGISMSACRE
F39H11.3_Cele    FENSK-EIGRGTYGLVYKAVPKKQNGQFPNKEYALKM----------IEGQGFSMSACRE
SSN3_Scer        YEVIG-YIAAGTYGKVYKAKRQIIKKP-LTVFYAIKKFKTEKDGVEQLHYTGISQSACRE
CDK19_Hsap       FEYEGCKVGRGTYGHVYKARRKDG--K-DEKEYALKQ----------IEGTGISMSACRE
CDK8_Hsap        FEYEGCKVGRGTYGHVYKAKRKDG--K-DDKDYALKQ----------IEGTGISMSACRE
Cdk8_Ddis        FSY---EIGSGTYGMVYKADDKKRPN----NKVAVKKFRS------TKEGEGLSLTAYRE
CDK8_Spur        ------KVGRGTYGHVYKATTKKE----PKKEYALKQ----------IEGTGISMSACRE
CC1G_07887_Ccin  YAILG-FISSGTYGRVYKAQSINGGE-----LLAIKKFKPDKEG-DVVTYTGISQSAIRE
AqueK099_Aque    MD-SGF---------ID------------------------------------ALSQK--
CDK8_Smoe        YELLG-KIGEGTYGLVYLAKSKLVSN--RGVKIAIKKFKQ------SKEGDGVSPTAIRE
                                :                                     : :

Cdk8_Dmel        IALLRELKHQNVITLIRVFLSHNDRKVFLLIDYAEHDLWHIIKFHRAAKATKK-QVVVPR
CDK8_Mmus        IALLRELKHPNVISLLKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKK-PVQLPR
CDK19_Mmus       IALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKK-PMQLPR
F39H11.3_Cele    IALFRELRHPNLICLQRVFLTN-EKKVWLLLDYAEHDLWHVIKHHRTAKSKKV-PIMVPR
SSN3_Scer        MALCRELHNKHLTTLVEIFLE--RKCVHMVYEYAEHDLLQIIHFHSHPE-----KRMIPP
CDK19_Hsap       IALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKK-PMQLPR
CDK8_Hsap        IALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKK-PVQLPR
Cdk8_Ddis        IGLLKELSNENIVKLLDVCLNPKDKLLYLIFDYAEFDLFGIIKYHRENG------SHFSD
CDK8_Spur        VALLRELRHPNVICLRRVFLSHSDRKVYLLCDFSEHDLWHIIKYHRANKASKKGPTSVPP
CC1G_07887_Ccin  IALNREINHENVVALREVILE--DKSIYMVFEYAEHDFLQVIHHYYQTI-----RTSIPT
AqueK099_Aque    -----------------------------------REKVEDLKYHRAVKGGKKPQVQVPK
CDK8_Smoe        IMLLRECMHENVVKLVDVHINHADMSLYLAFEYAEHDLYEIIRHHREKL-----LFQINP
                                                     :    ::.:            .

Cdk8_Dmel        GMVKSLLYQILDGIHYLHSNWVLHRDLKPANILV--------------------------
CDK8_Mmus        GMVKSLLYQILDGIHYLHANWVLHRDLKPANILV--------------------------
CDK19_Mmus       SMVKSLLYQILDGIHYLHANWVLHRDLKPANILV--------------------------
F39H11.3_Cele    NMVKNILFQILSGMHYLHSNWVLHRDLKPANILL--------------------------
SSN3_Scer        RMVRSIMWQLLDGVSYLHQNWVLHRDLKPANIMV--------------------------
CDK19_Hsap       SMVKSLLYQILDGIHYLHANWVLHRDLKPANILV--------------------------
CDK8_Hsap        GMVKSLLYQILDGIHYLHANWVLHRDLKPANILV--------------------------
Cdk8_Ddis        ATIKSLIWQVLNGIHYLHSNWVIHRDLKPSNILV--------------------------
CDK8_Spur        VMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGEGSERGRVKIADMGFARLFNSPLK
CC1G_07887_Ccin  AVLKSLIYQLFNGLIYLHASHILHRDLKPANILI--------------------------
AqueK099_Aque    TMVKSLMYQILSGIHYLHSNWVLHRDLKPANILV--------------------------
CDK8_Smoe        YTVKSLLWQILNGINYLHSNWIIHRDLKPSNILV--------------------------
                   ::.:::*::.*: *** . ::******:**::

Cdk8_Dmel        ------------------------------------------------------------
CDK8_Mmus        ------------------------------------------------------------
CDK19_Mmus       ------------------------------------------------------------
F39H11.3_Cele    ------------------------------------------------------------
SSN3_Scer        ------------------------------------------------------------
CDK19_Hsap       ------------------------------------------------------------
CDK8_Hsap        ------------------------------------------------------------
Cdk8_Ddis        ------------------------------------------------------------
CDK8_Spur        PLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSN
CC1G_07887_Ccin  ------------------------------------------------------------
AqueK099_Aque    ------------------------------------------------------------
CDK8_Smoe        ------------------------------------------------------------


Cdk8_Dmel        -------------------------------------------------------MG---
CDK8_Mmus        -------------------------------------------------------MG---
CDK19_Mmus       -------------------------------------------------------MG---
F39H11.3_Cele    -------------------------------------------------------MG---
SSN3_Scer        -------------------------------------------------------TI---
CDK19_Hsap       -------------------------------------------------------MG---
CDK8_Hsap        -------------------------------------------------------MG---
Cdk8_Ddis        -------------------------------------------------------MG---
CDK8_Spur        PYHHDQLDRIFNVMGFPQVPPVMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMG---
CC1G_07887_Ccin  -------------------------------------------------------TS---
AqueK099_Aque    -------------------------------------------------------MG---
CDK8_Smoe        -------------------------------------------------------MGVSG


Cdk8_Dmel        DGN--ERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWA
CDK8_Mmus        EGP--ERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWA
CDK19_Mmus       EGP--ERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWA
F39H11.3_Cele    DGPPDMRGRVKIADLGFSRIYANPLKPMAELDPVVVTFWYRAPELLLGAKHYTKAIDVWA
SSN3_Scer        D------GCVKIGDLGLARKFHNMLQTLYTGDKVVVTIWYRAPELLLGARHYTPAVDLWS
CDK19_Hsap       EGP--ERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWA
CDK8_Hsap        EGP--ERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWA
Cdk8_Ddis        EGK--ECGTVKIGDFGLARIFQSPLKPLNE-NGVVVTIWYRSPELLLGSKHYTRAVDIWA
CDK8_Spur        EGS--ERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWA
CC1G_07887_Ccin  Q------GVVKIGDLGLARLCYEPLQPLFAGDKVVVTIWYRAPELLMGAKHYNKAIDCWA
AqueK099_Aque    DGP--ERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGAKHYTKAIDIWA
CDK8_Smoe        DGD--EQGLVKIGDFGLARIYQAPLKPLSD-NGVVVTIWYRAPELLLGAKHYTCAVDMWA
                 :      * ***.*:*::*     *:.:   : ****:***:****:*::**. *:* *:

Cdk8_Dmel        IGCIFAELLTSEPIFHCRQE--DIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIKKMPEHH
CDK8_Mmus        IGCIFAELLTSEPIFHCRQE--DIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHS
CDK19_Mmus       IGCIFAELLTSEPIFHCRQE--DIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYP
F39H11.3_Cele    IGCIFAELLTAEPLFFCKEE--DIKAQNPYHYDQVKRIFHLLGYPSDADWPDMKKMPDHQ
SSN3_Scer        VGCIFAELIGLQPIFKGEEAKLDSKKTVPFQVNQLQRILEVLGTPDQKIWPYLEKYPEYD
CDK19_Hsap       IGCIFAELLTSEPIFHCRQE--DIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYP
CDK8_Hsap        IGCIFAELLTSEPIFHCRQE--DIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHS
Cdk8_Ddis        IGCIFAELITTKPLFPGKEK--DPKIPSLFQDDQVEKIIRVLGKPTLDMWPDIKHLPEWK
CDK8_Spur        IGCIFAELLTSEPIFHCRQE--DIKTSNPYHHDQLDRIFNVMGFPQEKDWEDIKKMPEHG
CC1G_07887_Ccin  VGCVMAELASLRPIFKGEEAKLDSKKNVPFQRDQLIKIFEVLGTPDERDWPGVVDMPEYR
AqueK099_Aque    IGCIFAELLTFEPIFHCRQE--DVEASSPYHREQLERIFLVMGFPHDRDWDDMKHMPEYS
CDK8_Smoe        VGCIFAELLTLKPLFQGA-E--DKTGPNPFQLDQLDKIFKVLGHPTTERWPMLSNLPHWL
                 :**::***   .*:*       *      :: :*: :*: ::* *    *  : . *.

Cdk8_Dmel        TLTKDFKRS-----TYSTCSLAKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQD
CDK8_Mmus        TLMKDFRRN-----TYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQD
CDK19_Mmus       TLQKDFRRT-----TYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQD
F39H11.3_Cele    RLLSDARNEGTPIQTFPN-SLHRYFDKWKINSQSSPYRLLVKLLTVDPTKRVSCEEAMND
SSN3_Scer        QITKFP--------KYRD-NLATWYH-SAGGRDKHALSLLYHLLNYDPIKRIDAFNALEH
CDK19_Hsap       TLQKDFRRT-----TYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQD
CDK8_Hsap        TLMKDFRRN-----TYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQD
Cdk8_Ddis        RLSSM---E-----AFPN-SLAKC---VGIDENSQAYDLLSKMILYDPSKRITASEALDH
CDK8_Spur        NLMKDFRRS-----NYASCCLPKYMEKHKVPKDSKAFQLLSKLLTMDPTKRMTSEQAMED
CC1G_07887_Ccin  NMKLLD--------HFSN-RLSDWCH-T-RIRSPQGYDLLRQLFAYDPDNRLTAEQAIQH
AqueK099_Aque    TLMRDFGRQK---ANFANCASQKYMDKHNVKHDTSAFKLLTKFLVMDPNKRITSDQAMLD
CDK8_Smoe        ANRQLIQSR-----KYDNPGLHTV---VNLQPKGLAFDLLSRMLEYDPVKRITAAQALDH
                                :                .     ** :::  ** :*: . :*: .

Cdk8_Dmel        QYF
CDK8_Mmus        PYF
CDK19_Mmus       PYF
F39H11.3_Cele    IYF
SSN3_Scer        KYF
CDK19_Hsap       PYF
CDK8_Hsap        PYF
Cdk8_Ddis        PYF
CDK8_Spur        QYF
CC1G_07887_Ccin  KWF
AqueK099_Aque    TYF
CDK8_Smoe        EYF
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