Protein (view, download) , Domain (view, download)
smi35A_Dmel      YEILEVIGK-GSFGQVIRALDHKTNTHVAIKIIRNKKRFLNQAVVELNILDELREKDADG
Dyrk3_Dmel       YEMLKIIGK-GSFGQVIKAYDHKTHEHVALKIVRNEKRFHRQAQEEIRILHHLRRHDKYN
DYRK4_Mmus       YEVLEMIGK-GSFGQVAKCLDHKNNELVALKIIRNKKRFHHQALVELKILEALRRKDKDN
DYRK3_Mmus       YEVLKIIGK-GSFGQVARVYDHKLRQYVALKMVRNEKRFHRQAAEEIRILEHLKKQDKTG
DYRK2_Mmus       YEVLKVIGK-GSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDN
mbk-2_Cele       YEVLKVIGK-GSFGQVIKAFDHKYQQYVALKLVRNEKRFHRQADEEIRILDHLRRQDSDG
C36B7.2_Cele     YTIDKVIGQ-GCYGVVGEATDGKTKQKVAIRMVS---KLAPRIYRETEMIMYISSIDPDH
C36B7.1_Cele     YSIDEVLSS-GYYAQVFRCTDKKTDKKVCIKLKN---RNLSTTYEETIILLRIHQLNRQN
DYRK4_Hsap       YEVLETIGK-GSFGQVAKCLDHKNNELVALKIIRNKKRFHQQALMELKILEALRKKDKDN
DYRK3_Hsap       YEVLKIIGK-GSFGQVARVYDHKLRQYVALKMVRNEKRFHRQAAEEIRILEHLKKQDKTG
DYRK2_Hsap       YEVLKVIGK-GSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDN
Dyrk2_Ddis       FEIVSILGQ-GSFCQVVKGYDYKTGEMVALKILRNQKRFHNQALTEIKILEYLKTNDPNS
5306_Tthe        YEIKEFLGK-GSFGQVLKVFDHKRKEYAALKVIRNKQKFHEQALIELNILHYIKEKDYDN
5356_Tthe        YELIEALGK-GSFGQVIKVFDHKRKEYSALKIIRNKKNFYNQAIVELNILKYIKDNDPQN
5655_Tthe        YELLECLGK-GSFGSVVKVFDHKRKEFLALKVIRNKKKFHNQALIELNILSYIKEQDKDE
DYRK2_Spur       YEVLKILGK-GSFGQVVKVYDHKTNQHIAVKMVRNEKRFHRQAQEEIRILEHLRKQDKDN
DYRK4_Spur       YEILEVIGK-GSFGQVVKAFDHKLGEMIAIKIIRNKKRFHHQALIEVKILDALRRKDRDN
CC1G_13957_Ccin  YEVVDTLGK-GSFGQVLNCRDHCTGESVAVKIIRNKKRFHHQALVEIKILDNLRKWDADE
AqueK112_Aque    YEIREIIGK-GSFGQVVKVFDHKTNQHIALKIIRNKKRFHHQALVEVKILDSLRKRDRDN
AqueK113_Aque    YEVLKVLGK-GSFGQVLKAYDHKMQTHIALKVVRNEKRFHRQAQEEVKILEHLRRQDKDN
DYRK2_b_Smoe     YEILGKLGR-GSFGQVLKCTDHKYKVPRAIKIIRNKKQFTQQAFIEINLLEFLRNKAAEE
DYRK2_a_Smoe     YEILGKLGR-GSFGQVLKCTDHKYKVPRAIKIIRNKKQFTQQAFIEINLLEFLRNKAAEE
GK034_Glam       YELVSKLGS-GSFGKVYKALDHKEQQFVALKIIKNRKRFQRQGLVEVKILELLRDNDPNG
GK033_Glam       YKLLKMVGS-ATFSNVFSCLDLKDNVTYCLKIIKQEKEFFDQAIDEVHLLELLKDIDPNN
GK032_Glam       YEIYKTIFEDSAFSVTLKARDLKEGKDVCLKVVNNEKDTLDQCLNEIRLLTYINKHDPTG
                 : :   :   . :  .    *       .:::             *  ::  :

smi35A_Dmel      --SHNVIHMLDYTYFRKHLCITFELMSLNLYELIKK-NN-----------YNGFSMSLIR
Dyrk3_Dmel       --TMNIIHMFDYFTFRNHTCITFELLSINLYELIKK-NG-----------FKGFSLQLVR
DYRK4_Mmus       --NHNVVHMKDFFYFRNHLCITFELLGINLYELMKN-NS-----------FHGFNLSIVR
DYRK3_Mmus       --SMNVIHMLESFTFRNHVCMAFELLSIDLYELIKK-NK-----------FQGFSVQLVR
DYRK2_Mmus       --TMNVIHMLENFTFRNHICMTFELLSMNLYELIKK-NK-----------FQGFSLPLVR
mbk-2_Cele       --THNIIHMLDYFNFRNHKCITFELLSINLYELIKR-NK-----------FQGFSLMLVR
C36B7.2_Cele     --TFDCVRMLDYNVFRGFHYVVTDLFDTSVKKYIKE-HH-----------PNGIALENVA
C36B7.1_Cele     --NSNCVRMLDYDHFRGHHFIVLENYQTDLASYLCGRSK-----------LTP---REYI
DYRK4_Hsap       --TYNVVHMKDFFYFRNHFCITFELLGINLYELMKN-NN-----------FQGFSLSIVR
DYRK3_Hsap       --SMNVIHMLESFTFRNHVCMAFELLSIDLYELIKK-NK-----------FQGFSVQLVR
DYRK2_Hsap       --TMNVIHMLENFTFRNHICMTFELLSMNLYELIKK-NK-----------FQGFSLPLVR
Dyrk2_Ddis       --TASIVHLNNYFYFRNHLILTFELLSMNLYDFLKV-NH-----------FQGYNLNLVR
5306_Tthe        --QTNIVKIRDFVIFRNHVCLVFELLSINLYDLLRN-NK-----------FQGLSLELIR
5356_Tthe        --QTNIVKIKDFVIFRSHVGLL--------------------------------------
5655_Tthe        --ATNIVRIKDFVIFRKHV-----------------------------------------
DYRK2_Spur       --NMNLIHMFESFSFRNHICITFELLSMNLYELIKK-NK-----------FQGFSLQLVR
DYRK4_Spur       --SHNVVHMREYFYYRNHLCITFELLGMNLYELIKK-NN-----------FQGFSVALIR
CC1G_13957_Ccin  --KHHVLKMTEHFYFRNHLCIATELLSINLYELIKA-NG-----------FVGFTTALIR
AqueK112_Aque    --QYNIIHMFDYFYFRNHLCITFELMGMNLYELIKK-NN-----------FQGFSISLIR
AqueK113_Aque    --AHNIIHMIDHFTFRNHVCITFELLSMNLYELIKK-NK-----------FQGFSLALVR
DYRK2_b_Smoe     GVDYNIVTIYESFEFRGHLCLSFAVHDISLFDMLKK-NH-----------FEGFNLSLVK
DYRK2_a_Smoe     GVDYNIVTIYESFEFRGHLCLSFAVHDISLFDMLKK-NH-----------FEGFNLSLVK
GK034_Glam       --DQCCVKVLSSFYFRSHLCIAFELLSINLYELLTK-KD-----------LKGLSLSLVR
GK033_Glam       --NINIIKIHDYFYFREHLLLKFTLLGEDLYTHFNR-REK-------KGQPNDYTIPVIR
GK032_Glam       --K-HFVRMTDYFYYGHRLIIIFELLTSNLFSYYSA-REAALPRTLLNPLATIFTMPRLQ
                       : : .   :

smi35A_Dmel      RFCNSIVKCLRLLYKENIIHCDLKPENILLKQRG------SSSIKVIDFGSSCYVDRK-I
Dyrk3_Dmel       KFAHSLLQCLDALYKNDIIHCDMKPENVLLKQQG------RSGIKVIDFGSSCFENQR-I
DYRK4_Mmus       RFTFSILKCLHMLYVEKIIHCDLKPENIVLYQRG------QVTVKVIDFGSSCYEHQK-V
DYRK3_Mmus       KFAQSILQSLDALHKNKIIHCDLKPENILLKHHG------RSATKVIDFGSSCFEYQK-L
DYRK2_Mmus       KFAHSILQCLDALHKNRIIHCDLKPENILLKQQG------RSSIKVIDFGSSCYEHQR-V
mbk-2_Cele       KFAYSMLLCLDLLQKNRLIHCDLKPENVLLKQQG------RSGIKVIDFGSSCFDDQR-I
C36B7.2_Cele     AMGRKILKGLVFLHEHNIVHGDLKPENIMLNLAN------PNDVKLGDFGLSRFAKPYHD
C36B7.1_Cele     PMIKSIVHGLKFLHQNKIIHGDLKPANVLLNEWN------RNNLKLTDFGLSTFVNQGPF
DYRK4_Hsap       RFTLSVLKCLQMLSVEKIIHCDLKPENIVLYQKG------QASVKVIDFGSSCYEHQK-V
DYRK3_Hsap       KFAQSILQSLDALHKNKIIHCDLKPENILLKHHG------RSSTKVIDFGSSCFEYQK-L
DYRK2_Hsap       KFAHSILQCLDALHKNRIIHCDLKPENILLKQQG------RSGIKVIDFGSSCYEHQR-V
Dyrk2_Ddis       RFGAQILTSLRFLSKRNIIHADLKPENILLKSPT------KSGIKLIDFGSSCFENEQ-I
5306_Tthe        RFAIQLLNAISFLKENRIIHCDLKPENVLLKQPN------KSGIKIADFGSSCFDDQV-M
5356_Tthe        -----------FLTKANIIHCDLKPENILLKQEN------KSGIKIVDFGSSCFENQR-V
5655_Tthe        -----ILNSINFLRKNRIIHCDLKPENILLKQAN------KSGVKLIDFGSSCFENER-L
DYRK2_Spur       KFAHSLLQCLEGLHRNKIIHCDLKPENILLKQQG------RSGIKVIDFGSSCYEHQR-I
DYRK4_Spur       RFAFSLLQCLRMLHKERIIHCDLKPENILLRQKG------QSTIKVIDFGSSCYEHQR-V
CC1G_13957_Ccin  RFTTQMLMSLSLMRHHRIVHCDLKPENVLLRHPA------KSAIKVIDFGSSCLEHEK--
AqueK112_Aque    RFAYSMLQCLKILYRERIIHCDLKPENILLRLRG------QSSIKVIDFGSSCYEHQR-V
AqueK113_Aque    KFAHSILQCLDSLYRNRIIHCDLKPENILLKQPG------RSGIKVIDFGSSCYEYQR-V
DYRK2_b_Smoe     CFARQVLVSLQFLHRARIIHGDLKPENILLQQPA------SPKIKLIDFGSSCFEHER-I
DYRK2_a_Smoe     CFARQVLVSLQFLHRARIIHGDLKPENILLQQPA------SPKIKLIDFGSSCFEHER-I
GK034_Glam       KFSLQLLIAFAYARKLRIIHADVKPENILLREPD------KSSIKVIDWGSGAMVSET-I
GK033_Glam       DMARQVLKALDYIHRLGITHLDLKPENLLHGDKNFIGGVNEPSVTLVDFGSSSFIFDK-M
GK032_Glam       HIARQILESLDFLHRLNILHLDLKHENLLLVNED----DDSFDIRLVDIGSSAFLYDE-C
                                  : * *:*  *::                : * * .

smi35A_Dmel      YTYIQSRFYRSPEVILGLQYGTAIDMWSLGCILAELYTGFPLFPGENEVE--------QL
Dyrk3_Dmel       YTYIQSRFYRAPEVILGGKYGRAIDMWSLGCILAELLSGHALFPGENESD--------QL
DYRK4_Mmus       YTYIQSRFYRSPEVILGHPYNMAIDMWSLGCIMAELYTGYPLFPGENEVE--------QL
DYRK3_Mmus       YTYIQSRFYRAPEIILGCRYSTPIDIWSFGCILAELLTGQPLFPGEDEGD--------QL
DYRK2_Mmus       YTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGD--------QL
mbk-2_Cele       YTYIQSRFYRAPEVILGTKYGMPIDMWSLGCILAELLTGYPLLPGEDEND--------QL
C36B7.2_Cele     HVQCQSMFYRAPEAFVRGRYNGATDMWSFGCTVAEMVSGKIFLAGDNCDD--------QF
C36B7.1_Cele     FRDYQTLYYKAPEVFCQGKVSVEIDIWSLGCVAAEIVRGTPLFVGDNYFD--------QF
DYRK4_Hsap       YTYIQSRFYRSPEVILGHPYDVAIDMWSLGCITAELYTGYPLFPGENEVE--------QL
DYRK3_Hsap       YTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPGEDEGD--------QL
DYRK2_Hsap       YTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGD--------QL
Dyrk2_Ddis       FTYIQSRFYRSPEVILGTKYDKSIDIWSLGCILVEIFTGVPLFPGSDEPE--------QL
5306_Tthe        YTYIQSRYYRSPEVILGIPYGTEIDMWSFGCIIAELFLGYPIFPGEDENE--------QM
5356_Tthe        YTYIQSRFYRAPEIILGLPYGKAIDMWSFGCIMAELYIGYPLFPGENEAE--------QF
5655_Tthe        YTYIQSRYYRAPEVILGLPYDTSIDMWSFGCIMAELFIGYPIFPGEDEQE--------QI
DYRK2_Spur       YTYIQSRFYRAPEVILGGKYGMPIDMWSLGCILAELLTGYPLLPGEDEGD--------QL
DYRK4_Spur       YTYIQSRFYRSPEVILGLPYGLPIDMWSFGCILAELYTGYPLFPGENEVE--------QL
CC1G_13957_Ccin  ---------------------------------TELYTGFPIFPGENEQE--------QL
AqueK112_Aque    YTYIQSRFYRSPEVILGLPYSMAIDMWSLGCILAELYTGYPLFPGENEVE--------QL
AqueK113_Aque    YTYIQSRFYRAPEVILGGKYGMSIDMWSFGCILAELLTGYPLFPGEDEGD--------QL
DYRK2_b_Smoe     YTYIQSRFYRAPEVILGLPYDMMIDVWSFACILAELFTGYPLFPGEDEVE--------QL
DYRK2_a_Smoe     YTYIQSRFYRAPEVILGLPYDMMIDVWSFACILAELFTGYPLFPGEDEVE--------QL
GK034_Glam       YSYIQSRFYRAPEVILGLPYGQEIDIWSIGCVLCELYTGLPIFPGDDERD--------QL
GK033_Glam       HSYIQSRSYRAPEVILATPYDSRADIWSFGCVVCELLTGRVLFPNYSVAT--------IL
GK032_Glam       STYVQSRSYRCPEVILGLPYDGRADVWSLGPILTELITGKVMFPIPQKADEDHKPYASML
                                                   *:  *  ::   .            :

smi35A_Dmel      ACIMEVLGLPPKVLISVARRRRLFFDS-RDAPRCITN-----------------------
Dyrk3_Dmel       ACIIEVLGMPNKNILA--------------------------------------------
DYRK4_Mmus       ACIMEVLGLPPAHFTQTASRRQVFFDS-KGLPKNINN-----------------------
DYRK3_Mmus       ACMIELLGMPPQKLLEQSKRAKYFINS-KGLPRYCSVST---------------------
DYRK2_Mmus       ACMIELLGMPSQKLLDASKRAKNFVSS-KGYPRYCTVTT---------------------
mbk-2_Cele       ALIIELLGMPPPKSLETAKRARTFITS-KGYPRYCTATS---------------------
C36B7.2_Cele     YLMQEVINIPPPVFFDTFYTNYYFFSTLKEAPKHIVI-----------------------
C36B7.1_Cele     ALIQEFFGKPSRKLFNTWGGIHQFYTE-YFFPRHCFEWL---------------------
DYRK4_Hsap       ACIMEVLGLPPAGFIQTASRRQTFFDS-KGFPKNITN-----------------------
DYRK3_Hsap       ACMMELLGMPPPKLLEQSKRAKYFINS-KGIPRYCSVTT---------------------
DYRK2_Hsap       ACMIELLGMPSQKLLDASKRAKNFVSS-KGYPRYCTVTT---------------------
Dyrk2_Ddis       ACIMEVLGAPPKSVIDNSTRKDIFFED-DGTPKPVKNS----------------------
5306_Tthe        GYIMELLGAPDSEFLKKCSRKKYFFDQ-NDQPLQIPN-----------------------
5356_Tthe        QMFMEILGIPEEEFVENCPRRNVFFEN-NKTPKVVKN-----------------------
5655_Tthe        GYIWEIIGAPSKDFLQNCTRRKYFFNE-DYTPKLIPN-----------------------
DYRK2_Spur       ACMIEVMGMPSQNLIDTSKRSKNFINS-KGQPRYCTVTT---------------------
DYRK4_Spur       ACIMEIFGLPPP------------------------------------------------
CC1G_13957_Ccin  SCIMEVLGVPDKEYINRSSRKKLFFDT-NGAPRPVVN-----------------------
AqueK112_Aque    ACIIEIFGLPDPALLAEAQRKKLFFDS-RGNPRCVTN-----------------------
AqueK113_Aque    ACMMEVLGLPSQKMIESTKRGRTFFSS-KGHPRYTTVNI---------------------
DYRK2_b_Smoe     AYMMEVLGTPPLSLISQAKRKKMFFDS-DNKPRIVPN-----------------------
DYRK2_a_Smoe     AYMMEVLGTPPLSLISQAKRKKMFFDS-DNKPRIVPN-----------------------
GK034_Glam       GKICELLGMPPNDMIFKSPRKNDFFVN-IGTGMGVAGVSEGGNPIFSGNLQQLSSVNEYL
GK033_Glam       SRICSLIGPIPRDMIMSGRMGQRVLTF-GLVPY---------------------------
GK032_Glam       AKLIGIIGPIPRDMILAGRESHKLFTK-DLFLF-ET------------------------
                   :  .:.

smi35A_Dmel      --------------------TKGRKR-S-----------PGSKS--------LAHILH-C
Dyrk3_Dmel       ------------------------------------------------------------
DYRK4_Mmus       --------------------NRGGKR-Y-----------PDSKD--------LTMVVK-T
DYRK3_Mmus       ----QTD-GR--VVLLGGRSRRGKKRGP-----------PGSKD--------WATALKGC
DYRK2_Mmus       ----LSD-GS--VVLNGGRSRRGKLRGP-----------PESRE--------WGNALKGC
mbk-2_Cele       ----MPD-GS--VVLAGARSKRGKMRGP-----------PASRS--------WSTALKNM
C36B7.2_Cele     -----TDHGP---IVSFIYTKAADHRKI-----------PGATP--------IGSFFTKT
C36B7.1_Cele     ----NPFNGDRTMEIEPHYKLAHPSRKP-----------PLTSS--------LVSKLPGG
DYRK4_Hsap       --------------------NRGKKR-Y-----------PDSKD--------LTMVLK-T
DYRK3_Hsap       ----QAD-GR--VVLVGGRSRRGKKRGP-----------PGSKD--------WGTALKGC
DYRK2_Hsap       ----LSD-GS--VVLNGGRSRRGKLRGP-----------PESRE--------WGNALKGC
Dyrk2_Ddis       --------------------TTGELY-T-----------IGTKS--------FKDSIR-S
5306_Tthe        --------------------SRGKIR-M-----------PNSKN--------WKSVIG-C
5356_Tthe        --------------------SRGKIR-T-----------PATKH--------INYYLR-C
5655_Tthe        --------------------SKGKIR-V-----------PNSKI--------LKAVLQ-T
DYRK2_Spur       ----LPD-GT--TVLNGGRSRRGKVRGP-----------PGSKD--------LVKALKGC
DYRK4_Spur       ------------------------------------------------------------
CC1G_13957_Ccin  --------------------SKGRRR-R-----------PGSKT--------LAQVLR-C
AqueK112_Aque    --------------------SKGKKR-R-----------PGSKD--------LSSAIK-T
AqueK113_Aque    ----NPD-GT--ASYTGGRSRRGKFRGP-----------PGTKD--------MSRALKGC
DYRK2_b_Smoe     --------------------SSGTRH-F-----------PSTKD--------LRMVVG-C
DYRK2_a_Smoe     --------------------SSGTRH-F-----------PSTKD--------LRMVVG-C
GK034_Glam       QATGRGA-GG--SEVPGIRLR--TTH-K-----------VNSKT--------LSGVLN-A
GK033_Glam       --------------E-HDEKNRQHFYF-----------TPQQGLLEYWLFGERCANLT-D
GK032_Glam       ---------R--EAILGNRDKAEGLRHAEIKGEDYVYVLPKKTTIKAML--GWDSHPE-Y


smi35A_Dmel      QDRYFIDFLQRCLEWDPAERMTPDEAAHHEFL
Dyrk3_Dmel       SDPLFLNFIRGCLEWDADKRLTPSEALKHPWL
DYRK4_Mmus       YDSSFLDFLRRCLVWEPSLRMTPEQALKHAWI
DYRK3_Mmus       GDYLFIEFLKRCLQWDPSARLTPAQALRHPWI
DYRK2_Mmus       DDPLFLDFLKQCLEWDPAVRMTPGQALRHPWL
mbk-2_Cele       GDELFVDFLKRCLDWDPETRMTPAQALKHKWL
C36B7.2_Cele     EQKPFNNFILKVFKWMPASRITAKQALDHPFF
C36B7.1_Cele     NQKFLARFLMRCFEWDPTERIKSSFILNHPFF
DYRK4_Hsap       YDTSFLDFLRRCLVWEPSLRMTPDQALKHAWI
DYRK3_Hsap       DDYLFIEFLKRCLHWDPSARLTPAQALRHPWI
DYRK2_Hsap       DDPLFLDFLKQCLEWDPAVRMTPGQALRHPWL
Dyrk2_Ddis       GDEDFDNFILDCLKWEPSQRITAEQGLKHDWI
5306_Tthe        TDDNFIDFIKKCLVWEPSQRLTPRDALLHPWI
5356_Tthe        PDENFIDFVSKCFTWKNHERMSPAEALVHDWI
5655_Tthe        ESEDFTDFLTKCFVWEPQKRLKPSDALMHPWI
DYRK2_Spur       DDPLFLDFLKRCLEWDPSSRMTPSQALRHSWL
DYRK4_Spur       -------------------------------H
CC1G_13957_Ccin  NDEEFIDFIAKCLVWDPERRMKPQAAMRHPFV
AqueK112_Aque    SDLLFLDFIRRCLVWSASERMKPEEALQHAWI
AqueK113_Aque    DDPQFLDFLRHCLEWDPAIRMTPPQALRHPWL
DYRK2_b_Smoe     SDKSFVNFLSCCLKWDKEQRMTPQQLLKHEWI
DYRK2_a_Smoe     SDKSFVNFLSCCLKWDKEQRMTPQQLLKHEWI
GK034_Glam       PD-DFISFISLFLQWDPQRRCTPEVAMSHPWI
GK033_Glam       EEVLFSDFCRQALIVDPIKRPTAAMLLEHPFI
GK032_Glam       CDDLFLDFIETIMRIDPRKRPTAAEALEHPWL