FRAP_Hsap MLGTGPAAATT----------------------------------A--------------
FRAP_Mmus MLGTGPAVATA----------------------------------S--------------
B0261.2_Cele MLQQHGISFQM---N-AD-------------------RQNKAATTSNR------------
TOR1_Scer MEPHEEQIWKS-KLLKAAN--------------NDMDMDRNVPLAPNLNVNMNMKMNASR
TOR2_Scer MNKYINKYTTPPNLLSLRQRAEGKHRTRKKLTHKSHSHDDEMSTTSNTDS----NHNGPN
Tor_Ddis MSQHE-------------------------------------------------------
FRAP_Spur MS----------------------------------------------------------
TOR_Dmel MSTTS-------------------------------------------------------
CC1G_00894_Ccin MASADQAP-----------------------------------VG---------------
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe MAGAQGVAP----------------------------------RP---------------
GK008_Glam MSTDA-------------------------------------------------------
FRAP_Hsap --------------------ATTS-SNVSVLQQFASGLKSRNEE----TRA-KAAKELQH
FRAP_Mmus --------------------AATS-SNVSVLQQFASGLKSRNEE----TRA-KAAKELQH
B0261.2_Cele ----IVSAPATNEFD----ERHRK-QGIDAARALASQYRSRITENRDANQR-QAARELSR
TOR1_Scer NGDEFGLTSSRF-DGVV-IGSNGDVNFKPILEKIFRELTSDYKE----ERK-LASISLFD
TOR2_Scer DSGRVITGSAGHIGKISFVDSELD-TTFSTLNLIFDKLKSDVPQ----ERA-SGANELST
Tor_Ddis ---------------------QPS-IWADALTKLLNDLKSKKEE----DRV-KASKNLKS
FRAP_Spur -----------------------------QMNSLVGGLKSRHDD----VRT-RAAKNLQH
TOR_Dmel -----------------------------VVQQFVNGLKSRNRN----VQN-KATQDLLF
CC1G_00894_Ccin ---------------------------DQQLNAIFSGLKSRSAD----TRM-QAAEDLKR
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe ---------------------------PDALQRLLSELRFKTAS----IKDGAAAAALRK
GK008_Glam ---------------------IT----SSRFYPYLADLKSIDPN----IYT-RAAMAIRM
FRAP_Hsap YVTMELREMSQEESTRFYD-QLNH--------HIFE-LVSSSDANERKGGILAIASLIGV
FRAP_Mmus YVTMELREMSQEESTRFYD-QLNH--------HIFE-LVSSSDANERKGGILAIASLIGV
B0261.2_Cele YVRSELKDEPNTFSDAFLN-AIDGRTDIASQSAIYNCMKSNSNIDQKRAGIYLIVCLAET
TOR1_Scer LLVSLEHELSIEEFQAVSN-DINN--------KILE-LVHTKKTSTRVGAVLSIDTLISF
TOR2_Scer TLTSLAREVSAEQFQRFSN-SLNN--------KIFE-LIHGFTSSEKIGGILAVDTLISF
Tor_Ddis YVISQSREMTNENFTKFMN-ELNNN-------LIFE-LVNSSVIPEKIGGIMAIDELIDV
FRAP_Spur YVSTELREVSADERTSFMD-ELNH--------HIFE-LVSSQDVSEKKGGILAIVSLIGI
TOR_Dmel YVKTELREMSQEELAQFFD-EFDHH--------IFT-MVNATDINEKKGGALAMKCLINC
CC1G_00894_Ccin FVQVSYAEMTSDAAAKLWDDHINRR--------LFA-LIHSQNINEAFGGLLGIERLLEL
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe HVQEEARDLSAEGLTKFLD-ILYDR--------INC-LIESADVSDNLGALRAIDVLIDV
GK008_Glam QVEKDSRQMLADPRTLFIS-DLMS--------FIRN-LATSSSYEDRLASLWVMRELIQS
FRAP_Hsap EGG----NATRIGRFANYLRNLLP-SN---DPVVMEMASKAIGRLAMAGD--TFTAEYVE
FRAP_Mmus EGG----NSTRIGRFANYLRNLLP-SS---DPVVMEMASKAIGRLAMAGD--TFTAEYVE
B0261.2_Cele HS-------GNVIRYANYLLKMLN-NGNGLDEDTVKMASKALAFLIATCK--SYAAELVD
TOR1_Scer YAYT-ERLPNETSRLAGYLRGLIP-SN---DVEVMRLAAKTLGKLAVPGG--TYTSDFVE
TOR2_Scer YLST-EELPNQTSRLANYLRVLIP-SS---DIEVMRLAANTLGRLTVPGG--TLTSDFVE
Tor_Ddis DYD---ENATKITRLANYLRIGLG-FN---DFTVMLMASKALGRLARSSG--TLTAEFVE
FRAP_Spur DGD----NATRITRFANYLRNLLP-SN---DVVVMEMAAKAIGHLALAGG--TFTPEYVD
TOR_Dmel EGSLT--ARKGISPYLNRLRDLLL-IN---DVSVMEIAARSLVKLANMPT--SKGADSFD
CC1G_00894_Ccin DLEETIESKRNHFRFYNYVKHLLP-NP---DVHLMMAASKTLGKIAEIGGGVAFGERFME
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe ELGES--A-TKTMKFANCVKRVLEEKQ---DPDVLVRASEVLGHIVSTG---PQTADIVE
GK008_Glam RPT---ISMIPLTYFEEIALELVN-DP---SEVIILTNCVFIGRLINAEG--H-GIDFVP
FRAP_Hsap FEVKRALEW-LGA------------DRNEGRRHAAVLVLRELAISVPTFFF--QQVQPFF
FRAP_Mmus FEVKRALEW-LGA------------DRNEGRRHAAVLVLRELAISVPTFFF--QQVQPFF
B0261.2_Cele RCLDHCHEW-LGQNVPHSQQPKNQQEIDQIRRLAASHLSRELALATPTAFF--LRVNLFF
TOR1_Scer FEIKSCLEW-LTASTEKNS---FSSSKPDHAKHAALLIITALAENCPYLLY--QYLNSIL
TOR2_Scer FEVRTCIDW-LTLTADNN----SSSSKLEYRRHAALLIIKALADNSPYLLY--PYVNSIL
Tor_Ddis FEVTRALEW-LSG------------DRIEARRHAAVLVLKELAQNAPTLFY--VHASSFV
FRAP_Spur FEVKRALEW-LGG------------DRQEGRRHAA-------------------------
TOR_Dmel FDIKKAFEV-LRGE------------RQEYRRHSAVFILRELAIALPTYFY--QHILTFF
CC1G_00894_Ccin YEIPAAIEL-MQPD------------KQEAPRYAGVLILKELARNSPTYFH--PHIGIVF
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe SQVSCALKW-LR---------------GESRRFAAVLILKEMADQAPTVFN--VHVPEFV
GK008_Glam KLFVISIDKIKSGD--------------STKVYTGMLLFNDLTEVE-TSFAIDISSEEFL
FRAP_Hsap DNIFVAVWDPKQ-AIREGAVAALRACLILTTQREPK-EMQKPQWYRHTFEEAEKGFDETL
FRAP_Mmus DNIFVAVWDPKQ-AIREGAVAALRACLILTTQREPK-EMQKPQWYRHTFEEAEKGFDETL
B0261.2_Cele KYIFNAVRDKNP-AVRIAGIDALHVVLTIVSQREAKN---KTEWFKKCFDEALEGQPNPS
TOR1_Scer DNIWRALRDPHL-VIRIDASITLAKCLSTLRNRDPQ---LTSQWVQRLATSCEYGFQV--
TOR2_Scer DNIWVPLRDAKL-IIRLDAAVALGKCLTIIQDRDPA---LGKQWFQRLFQGCTHGLSL--
Tor_Ddis DLIWVALKDPKV-AIREGAVEALRACLELISERESR---LRLQWYQKIYDEAQKSFKQNG
FRAP_Spur -----------Q-AIREAAVSALRACLELTAQRETK-EMQKPQWYKQTYEEAEKGFEETG
TOR_Dmel EVIFNAIFDPKP-AIRESAGEALRAALIVTAQRESTKQSSEPQWYRICYDEANGSFNADL
CC1G_00894_Ccin DNILLPLRDPRL-HVREGAADLLANCLEIVCSRERQT---RNPYLYKILQDAQAGLKS--
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe DAIWIALRDPRQ-AIREHAVEALRACLTVIVTRETRW---RVRWYYRMFEATQDGLGKN-
GK008_Glam EPIWHVITETRNSNIKEVGFKAINKFISY---QKKA-TK--HDVLVRLITMIRAALDG--
FRAP_Hsap A---KEKGMN-RDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYCKDLMG
FRAP_Mmus A---KEKGMN-RDDRIHGALLILNELVRISSMEGERLREEMEEITQQQLVHDKYCKDLMG
B0261.2_Cele -------QKD-DLDRWHAVALILNELLRISDQRFELIRCESSQFIKQKFLKED-----EE
TOR1_Scer ---------N-TLECIHASLLVYKEILFLKD-----------------------------
TOR2_Scer ---------N-TNDSVHATLLVFRELLSLKA-----------------------------
Tor_Ddis -----------SPESIHGSLITVSELLRNTG-----------------------------
FRAP_Spur K---GEKGLN-RDDRAHGALLIINELIRTSSREGERLRQEMEEVSQQQTQHEHSFRDLGS
TOR_Dmel GSSKDQKGVT-RDDRIHGGLVVFNELFRCANATWERRYTSLKTLFP-KTQHNKFLEASSS
CC1G_00894_Ccin ---------S-QPEVIHGSLAAYRELLLHAG-----------------------------
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe ---------A-TVESIHGSLLAVGELLRNTG-----------------------------
GK008_Glam ------KNISEQLIALHL--LLNM------------------------------------
FRAP_Hsap FGTKPRHITPFTSFQAVQPQQSNALVGLLGYSSHQGLMGFGTS----PSPAKSTLVESRC
FRAP_Mmus FGTKPRHITPFTSFQAVQPQQPNALVGLLGYSSPQGLMGFGTS----PSPAKSTLVESRC
B0261.2_Cele EG---------VE--------------------------------WLVLTKQQTIVESVT
TOR1_Scer ------------------------------------------------------------
TOR2_Scer ------------------------------------------------------------
Tor_Ddis ------------------------------------------------------------
FRAP_Spur SSNKAKS--P------TGPQLGHNQYVQRALASPLSLVATGIQ----PK---PRITESRY
TOR_Dmel SSMG-------SQLNTLVPRLKVPFIDKL--GSTQTHLGEGEHHKGVAKFASHNVLESAY
CC1G_00894_Ccin ------------------------------------------------------------
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe ------------------------------------------------------------
GK008_Glam ---------------------------------------------------LNLSVKDKS
FRAP_Hsap CRDLMEEKFDQVCQWVLK----------CRNSKNSLIQMTILNLLPRLAAFRPSA--FTD
FRAP_Mmus CRDLMEEKFDQVCQWVLK----------CRSSKNSLIQMTILNLLPRLAAFRPSA--FTD
B0261.2_Cele ARKLVLERFPKILDCVRQIIPLANKTSSTKQQSSIYLNTVLMQLLPRICAFPQCDRTFQ-
TOR1_Scer --PFLNQVFDQMCLNCIA----------YENHKAKMIREKIYQIVPLLASFNPQL--FA-
TOR2_Scer --PYLRDKYDDIYKSTMK----------YKEYKFDVIRREVYAILPLLAAFDPAI--FT-
Tor_Ddis --DFMLSKFKDICETVLK----------YKDHRDKLVKKTVLALFPRLAVFCSRD--FV-
FRAP_Spur CLELMQENFDIVCQQVLK----------FCGSRNPLIQQILLNLLPRLAAFEPKM--FV-
TOR_Dmel AQEILQEHYTSICDNVLE----------QRTSKSPYVQQALLQILPRLAAFNRAV--FV-
CC1G_00894_Ccin --MFMQENFLDTAEAILR----------FKSSRDPLVRRMVITMIPTLAAYDTQT--FT-
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe --EFMMSRYKEVLDIAFK----------FRDHRDRLVRRSITSLLPRIAHFLRDR--FV-
GK008_Glam IADYFQENYSSFFSLVAN----------IFRSKTSEGRMLVASIISLFAKLDPER--FCT
FRAP_Hsap TQYLQDTMNHVLSCVK-KE---------KERTAAFQALGLLSVAVRS-EFKVYLPRVLDI
FRAP_Mmus TQYLQDTMNHVLSCVK-KE---------KERTAAFQALGLLSVAVRS-EFKVYLPRVLDI
B0261.2_Cele TISFDTSF----TIL-------------QRNAVAAPAIGMMMLSNPD-VHATHIEKTISF
TOR1_Scer GKYLHQIMDNYLEILT-NAPANKIPHLKDDKPQILISIGDIAYEVGP-DIAPYVKQILDY
TOR2_Scer KKYLDRIMVHYLRYLK-NIDMNA--ANNSDKPFILVSIGDIAFEVGS-SISPYMTLILDN
Tor_Ddis LNYFNACMNHLLAALR-NQ---------NERPTAFIALGEIAMAVGG-SIKPYLDSIVVM
FRAP_Spur TSYLEDTVKYMLISLR-RE---------RERSNAFQAVGLLAVAVKG-NITEHLGKILEI
TOR_Dmel EKYLQTCVSHLMQILRGKE---------KDRTVAYITIGYMAVAVQS-AIEVHLSSIMTS
CC1G_00894_Ccin EHFLHKAMAHLLTQLD-KA---------PERNFAFIAIGHTALAVGS-DMKPFLDPIMDN
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe TSYFTTSMDHLLAVMR-NP---------SERSTGFAALGEMAGAVGC-ALGEYLPAIMNF
GK008_Glam TERLQMILTFYKKMIP-------------TQQELFIPLGEFVIVIGEKHVKPIFNDLINL
FRAP_Hsap IRAALPPKD---------------FAHKRQKAMQVDATVFTCISMLARAMGPGIQQDI-K
FRAP_Mmus IRAALPPKD---------------FAHKRQKTVQVDATVFTCISMLARAMGPGIQQDI-K
B0261.2_Cele ISAAIK--------------------K--TTNSDVLDNYFTFLFLFVDAYHEQVTTQI-K
TOR1_Scer IEHDLQTKF--------------------KFRKKFENEIFYCIGRLAVPLGPVLGKLLNR
TOR2_Scer IREGLRTKF--------------------KVRKQFEKDLFYCIGKLACALGPAFAKHLNK
Tor_Ddis IKQGLMTK--------------------G---KQFCPEVLTCISMLASAVGQSMYPHM-Q
FRAP_Spur VRSSLPHKD---------------IPHRKHKSIIVDPAVFTCISMLARAVGPVIARDV-K
TOR_Dmel VKVALPSKD---------------LTS--KRKVPVDPAVFACITLLAHAVKSEIADDV-K
CC1G_00894_Ccin VRSCLQNRG--------------------RKNAPSEEPIFQCIGMLAAAVGPNLTKLL-H
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe IRDAVLYFSSVGFYILILYFFVCQLQP--RRGKP-SMEAIACVGNLTEALGPLMEEHV-R
GK008_Glam ITSSFKSQN---------------FT---KAGSILPPEPLKCIQYITKGAPNLVQKHV-T
FRAP_Hsap ELLEPM-LAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLR--------
FRAP_Mmus ELLEPM-LAVGLSPALTAVLYDLSRQIPQLKKDIQDGLLKMLSLVLMHKPLR--------
B0261.2_Cele AIIPQL-MDITLSRSLANVLKMIMMRIPKLRLNVQDGVMASVYQTLTGSLIP--------
TOR1_Scer NILDLM-FKCPLSDYMQETFQILTERIPSLGPKINDELLNLVCSTLSGTPFI--------
TOR2_Scer DLLNLM-LNCPMSDHMQETLMILNEKIPSLESTVNSRILNLLSISLSGEKFI--------
Tor_Ddis VILPQMIVSSGLTVVLTDALRDLTINLPTLIPNIQYKLLNLISQVLANKPFS--------
FRAP_Spur ELLEPM-LAVGLSPALTAALHDLAKQIPQLKKDIQDGLLKMLSLVLMHKPLR--------
TOR_Dmel DILEQM-FYTGLSPALTVCLRELSENVPQLKSAITEGLIGILSQVLMNKAAI--------
CC1G_00894_Ccin DQLDLM-LACGLSEPLSQALAAIAKYIPPLLKTIQDRLLQLLSMLLSGQPYR--------
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe STLDIM-FDTGLTPTLEKALNQIVTSLPSFLPPIQERLLDFISLVLCKAPYF--------
GK008_Glam SILECI-FSVGLCESLTSALQDLSANLHNRLLDIQGLLLYLVANELGGINLFLSNAYGVI
FRAP_Hsap ---------------------------------HPGMPKGLAH-----------------
FRAP_Mmus ---------------------------------HPGMPKGLAH-----------------
B0261.2_Cele ---------------------------------PKSEP--IGR-----------------
TOR1_Scer ---------------------------------QPGSPMEIPS-FSR-----------ER
TOR2_Scer ---------------------------------QSNQYDFNNQ-FSI-----------EK
Tor_Ddis ---------------------------------EPGAPSPYRK----------------S
FRAP_Spur ---------------------------------HPGTPRALLS-----------------
TOR_Dmel ---------------------------------LPYT-----------------------
CC1G_00894_Ccin ---------------------------------PLGAPAPLGR----------------N
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe ---------------------------------SQRKSLLV-------------------
GK008_Glam DGSEDYYLVLTENQSQAVADGHDSGVLDSQTSIIPGTRPSTTQATTHVEDTRTNEDAIEL
FRAP_Hsap --QLASPG---------------------------------------LT----TLPEASD
FRAP_Mmus --QLASPG---------------------------------------LT----TLPEASD
B0261.2_Cele --PASPKA---------------------------------------I--LQKAETDPKE
TOR1_Scer AREWRNKN---------------------------I-----------LQKTGESNDDNND
TOR2_Scer ARKSRNQS---------------------------F-----------MKKTGESNDDITD
Tor_Ddis ATPFQGGS---------------------------------------IPQ--LGQNSDVD
FRAP_Spur --PTGQTG---------------------------------------TA---LSSIDSGD
TOR_Dmel ---ALPTI---------------------------------------A--IDGSLMQNGD
CC1G_00894_Ccin EFPAPPNQ---------------------------------------LT-ATQMTTTDKN
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe ---RLPQK---------------------------------------A--VGLPSSEIQG
GK008_Glam AHDLSITGLKEESEQCDFKNSLSVYQTVTTSAGITALYKLSDRIATALGTSKLRPRRHST
FRAP_Hsap VGSITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHL-I
FRAP_Mmus VASITLALRTLGSFEFEGHSLTQFVRHCADHFLNSEHKEIRMEAARTCSRLLTPSIHL-I
B0261.2_Cele LQRIVLAVDVLGEFYFSRGALQRIMQYVADYYLTADNVEIRLAAVSSCCEMVVPFVGV-Y
TOR1_Scer IKIIIQAFRMLKNIK-SRFSLVEFVRIVALSYIEHTDPRVRKLAALTSCEIYVKDN----
TOR2_Scer AQILIQCFKMLQLIH-HQYSLTEFVRLITISYIEHEDSSVRKLAALTSCDLFIKDD----
Tor_Ddis PQMIALALKTLGSFDFSKHNLLEFVRECVVNYLDDDNIEIRREAAITCAQLMVGTE----
FRAP_Spur LTSTVLALRTLGNFDFEGHSLTQFVRHCADHFLSSEHKEIRIEAARTCSSLLQPAVNV-S
TOR_Dmel GATTVLALKTLGTFNFEEQNMLDFVQRCADYFIVHEQQEIRLEAVQTCTRLLKLAVQ---
CC1G_00894_Ccin SELITLALKTLGTFDFSGHVLNEFVRSCALPYLEDDNPQVRCAAAETCCTLFIKD-----
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe PALVQLALKILTNFNFKGHDLLEFAREAVVMHLEDDDAGVRRHAARCCCRLVEHSYQ---
GK008_Glam SEAILLAFQALYDFDFSLFDLTIFAADYLTRYLRNDSSTLRIKAAQTILKLMSEDHFEKI
FRAP_Hsap SG--------------------------------------------HA------------
FRAP_Mmus SG--------------------------------------------HA------------
B0261.2_Cele KK--------------------------------------------VT------------
TOR1_Scer ----------------------------------------------IC------------
TOR2_Scer ----------------------------------------------IC------------
Tor_Ddis ----------------------------------------------EP------------
FRAP_Spur ------------------------------------------------------------
TOR_Dmel SS--------------------------------------------ES------------
CC1G_00894_Ccin -P--------------------------------------------IC------------
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe TA--------------------------------------------IT------------
GK008_Glam RRGKHSQYKSMTIKAEDCHSWAGSTLGEAPTPSGGATIIPPAVVSNQSFATTISPKTRHI
FRAP_Hsap -HVV------------S--------------------------------------QTAVQ
FRAP_Mmus -HVV------------S--------------------------------------QTAVQ
B0261.2_Cele -SDK------------R--------------------------------------NSLLQ
TOR1_Scer -KQT------------S--------------------------------------LHSLN
TOR2_Scer -KQT------------S--------------------------------------VHALH
Tor_Ddis -TPT------------R--------------------------------------GHSAV
FRAP_Spur ------------------------------------------------------------
TOR_Dmel -MEN------------S--------------------------------------KTLSD
CC1G_00894_Ccin -YQA------------S--------------------------------------SHAIE
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe -GRSASRLTSGRPLTFR--------------------------------------KHR-I
GK008_Glam RTHS------------SSHLDDMSSTSFCINQDCILSQDILKSSDLGTDGFFNSGPYRHM
FRAP_Hsap VVADVLSKLLVVGITDPDPDIRYCVLASLD---ERFDAHLAQAENLQALFVALNDQVFEI
FRAP_Mmus VVADVLSKLLVVGITDPDPDIRYCVLASLD---ERFDAHLAQAENLQALFVALNDQVFEI
B0261.2_Cele TIYGVLRAVCSVIVNDQDVRVRMQVISCFGQMPRPFLAHLAQPEMLEVQFMALHDEKLEM
TOR1_Scer TVSEVLSKLLAITIADPLQDIRLEVLKNLN---PCFDPQLAQPDNLRLLFTALHDESFNI
TOR2_Scer SVSEVLSKLLMIAITDPVAEIRLEILQHLG---SNFDPQLAQPDNLRLLFMALNDEIFGI
Tor_Ddis IVGEVLEKLLVVGIADPDPSIRKTVLSSLE---ARFDHYLAQAENLRSLFIALNDELFEI
FRAP_Spur ------------------------------------------------------------
TOR_Dmel TVSHVIERLLMVAITDMDCNVRIRILRSLD---ETFDGKLAQPESLNSLFITLHDEIFEI
CC1G_00894_Ccin VISDVLDKLLTVGIADPDPGIRNVVLRGLH---ERFDKHLAQAENVRSLFIALNDEVMAN
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe LIEEILEKLLVAAVSDTDASVREDVFVSLGT-NGSFYDFLAQADCLKAIFIAFNDQSFEV
GK008_Glam LISDTLRQIIIIGTTDIDPEVRMSIIQALTT-TNRYDIYLVHESSLRTLFIALYDDNIEI
FRAP_Hsap RELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRL
FRAP_Mmus RELAICTVGRLSSMNPAFVMPFLRKMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRL
B0261.2_Cele QQACVTLLGRLAELNPALVLPRLRLMLLETLSQMQQSGQARLEQHSAKMIAQLAKQSPKF
TOR1_Scer QSVAMELVGRLSSVNPAYVIPSIRKILLELLTKLKFSTSSREKEETASLLCTLIRSSKDV
TOR2_Scer QLEAIKIIGRLSSVNPAYVVPSLRKTLLELLTQLKFSNMPKKKEESATLLCTLINSSDEV
Tor_Ddis RELAITVIGRLTIRNPAYVMPSLRKTLIQLLTELEFSGDGRNKEESARLLGHLISASEKL
FRAP_Spur ------------------------------------------------------------
TOR_Dmel RELAMVTIGRLSSINPAYVMPKLRTTMIELITDLKYSGMSRNKEQSAKMLDHLVISTPRL
CC1G_00894_Ccin REAAVGLIGRLAKHNPAYVMPSLRKALIQLLTELEYSTVMRNREDCTRLLTLLVSATQRL
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe RKLSIVMAGKLSDKNAAYVCPALRRHLQQLLTDMEHSADSKSKEESAILLGSLIRACETL
GK008_Glam RILAVKLIGRLCSLNPALVTPEIRHLILVLLTELRLTTENNKRATSNELIVKIFKFCGSI
FRAP_Hsap IRPYMEPILKALILKLKDPD-PDPNPGVINNVLATIGELAQVSG--LEMRKWVDELFIII
FRAP_Mmus IRPYMEPILKALILKLKDPD-PDPNPGVINNVLATIGELAQVSG--LEMRKWVDELFIII
B0261.2_Cele MRPYVGSLMIAMIPKLRNDQ---KYAEVTAQVLNAVSEIAVIGG--AEIVKNLKPLFEKL
TOR1_Scer AKPYIEPLLNVLLPKFQDT-----SSTVASTALRTIGELSVVGG--EDMKIYLKDLFPLI
TOR2_Scer AKPYIDPILDVILPKCQDA-----SSAVASTALKVLGELSVVGG--KEMTRYLKELMPLI
Tor_Ddis IKPYVEPILKALLPKLRDS-----NPRVASCVLAALGELSVVGG--EEMVQHIDSLLPLI
FRAP_Spur ------------------------------------------------------------
TOR_Dmel ISSYMNPILKALVPKLHEPE---SNPGVILNVLRTIGDLAEVNGGSDEMELWADDLLSIL
CC1G_00894_Ccin IKPYAIPMLRVLLQKANDP-----NPAVAANVLMCLGELACVAG--EDAMPHVQELMQII
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe ITPYVIPIHKALVARLSEGSGGSGNIGVVSGVMATVGELARVAG--CAIRPHIKDLMPLI
GK008_Glam VLPYVPMVYSAVMGLISKDC--D-DEYLLITSLTTLAELFTIGS--TSMVHCLAEVIPLL
FRAP_Hsap MDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFL-KTEQNQGTRRE
FRAP_Mmus MDMLQDSSLLAKRQVALWTLGQLVASTGYVVEPYRKYPTLLEVLLNFL-KTEQNQGTRRE
B0261.2_Cele THMINDSSSLHKREAALRAIGGICRSTAYVVDPYRDYPSLLDDLLRIL-KTVMSNTMRRE
TOR1_Scer IKTFQDQSNSFKREAALKALGQLAASSGYVIDPLLDYPELLGILVNIL-KTENSQNIRRQ
TOR2_Scer INTFQDQSNSFKRDAALTTLGQLAASSGYVVGPLLDYPELLGILINIL-KTENNPHIRRG
Tor_Ddis IDTLQDQSSTSKREVALKTLAQLASSTGYVIKPFSKYPMLLDTLLNAI-KTERIGSIRRE
FRAP_Spur ------------------------------------------------------------
TOR_Dmel LEMLGDAGSPDKRGVALWTLGQLISATGRVVTPYHKYPVLIDILINFL-KTEQRRSIRRE
CC1G_00894_Ccin LAKLADPQT-LKRDAALHALGQVCSSTGYVVQPLLDHPQLLPLLGRIM-RTETSVQTRRE
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe VDALRDTSAASKRDVAVRTLGQLVQNTGYVVTPYTEFPHLLGLLLRILLNGELEWSTRNE
GK008_Glam ITCIKEETSKTLRLTTTRCFVRIVEATSFVVFPWFIYHDLFTIVFGIL-KNDTSQEIRLE
FRAP_Hsap AIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLS-------------------------
FRAP_Mmus AIRVLGLLGALDPYKHKVNIGMIDQSRDASAVSLS-------------------------
B0261.2_Cele AIKTLGILGAIDPYTHKVFTGSVQSS-TAISTALS-------------------------
TOR1_Scer TVTLIGILGAIDPYRQKEREVTS--T--------T-------------------------
TOR2_Scer TVRLIGILGALDPYKHREIEVTS--N--------S-------------------------
Tor_Ddis VIKVLGILGSLDPYKHKMNELGK-RR--------E-------------------------
FRAP_Spur ------------------------------------------------------------
TOR_Dmel TIRVLGLLGAMDPYKHKMNKGLIDSQKDNVLIAYS-------------------------
CC1G_00894_Ccin VVKVLGILGALDPYRRKSRPDEDVAS-N------A-------------------------
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe VLKVLGVIGALDPHVNKRNELRLHPS-DGNRSSLS-------------------------
GK008_Glam AAKLITTIGAIDPIFYQNGKPDL--SALVPPTNLTCKCQSTDVFSLDYIMDESNIWVCHK
FRAP_Hsap -ESKSSQDSSDYSTSEML------------------V--NMG-NLPLDEFYPAV--SMVA
FRAP_Mmus -ESKSSQDSSDYSTSEML------------------V--NMG-NLPLDEFYPAV--SMVA
B0261.2_Cele -LPISETDSKDPRQDIIH------------------W--FNYEKCTLEEFYPAI--TIAN
TOR1_Scer -D--ISTEQNAPPIDIAL------------------L--MQGMSPSNDEYYTTV--VIHC
TOR2_Scer -K--SSVEQNAPSIDIAL------------------L--MQGVSPSNDEYYPTV--VIHN
Tor_Ddis -DPKANDDKNNNMTNE-V------------------I--TI--SPSNEDYYPTV--ALTA
FRAP_Spur ------------------------------------------------------------
TOR_Dmel -DGKVD-ESQDIST--AE------------------L--LVNMGNALDEYYPAV--AIAA
CC1G_00894_Ccin -ETSVA-AVN----QVPI------------------N--PHPTSSSSDDYFQTV--VITS
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe -ETVHG-QTNDESLMEAW------------------P--TGGISAATEDYYSTVKVAINA
GK008_Glam GEGGAAQEASIKSHGKAVVSPITGHVVENVYIMKLDSGSEVSANVSDFELTLNV--IMST
FRAP_Hsap LMRIFRDQSLSHHHTMVVQAITFIFKS-LGLKCVQFLPQVMPTFLNVIRVC-----DGAI
FRAP_Mmus LMRIFRDQSLSHHHTMVVQAITFIFKS-LGLKCVQFLPQVMPTFLNVIRVC-----DGAI
B0261.2_Cele LMLMMQDEDSQ-SYAEIAQAIVTIFRS-LGDMAPLYTEQVIPRLIEVCRRATESSNRANL
TOR1_Scer LLKILKDPSLSSYHTAVIQAIMHIFQT-LGLKCVSFLDQIIPTILDVMRTC-----SQSL
TOR2_Scer LMKILNDPSLSIHHTAAIQAIMHIFQN-LGLRCVSFLDQIIPGIILVMRSC-----PPSQ
Tor_Ddis LMKILRDPSLSSHHTSVIQAVMYIFKS-LSLKSIPFLPQIMPPFLHAMNTG-----EPLF
FRAP_Spur ------------------------------------------------------------
TOR_Dmel LMRILRDPTLSTRHTSVVQAVTFIFQS-LGIKCVPYLAQVLPNLLDNVRTA-----DNNL
CC1G_00894_Ccin LLAILKDQSLSSHHHTVIEAIMSIFKT-QGLKCVTFLPQIIPAFAAITRTS-----IARL
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe LMRTLRDPSSSIYHQSVVKSLMYIC-------------KVMPDLLLTIRNC-----EDNL
GK008_Glam LYSILSESTLDMYHYDAVVVFRTIIQTECTAISLPMVPKIISLILENIQNC-----KVFM
FRAP_Hsap REFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMN---TSIQSTIILLIEQIVVALGG
FRAP_Mmus REFLFQQLGMLVSFVKSHIRPYMDEIVTLMREFWVMN---TSIQSTIILLIEQIVVALGG
B0261.2_Cele REFFLQQLANFVAIIRKHAAPYMPAIFTIIADAWKED---ISVKMVVIEVLTDMGTAIGN
TOR1_Scer LEFYFQQLCSLIIIVRQHIRPHVDSIFQAIKDFSSV----AKLQITLVSVIEAISKALEG
TOR2_Scer LDFYFQQLGSLISIVKQHIRPHVEKIYGVIREFFPI----IKLQITIISVIESISKALEG
Tor_Ddis REFLFQQLGSLVSIVKQHIRDYLVNVFALIEKYWNS-----NLLIPIIKLVEEISSALND
FRAP_Spur ------------------------------------------------------------
TOR_Dmel REFLFQQLAILVAFVKLHIISYMGDIFKLIKEFWTIN---TPLQNTLINLIEQIAVALGC
CC1G_00894_Ccin QEFHLQQLAILVGIIKQHIRNYTLDVFSLITELWD-N---VTLQLPIVALIEALGKALDA
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe REFIFCQLADLVAIVRQHIRKYLSSILSLVLDMILPTSPRSASHSPILHLVERLCVALHD
GK008_Glam QETMLRELILIISSIGHHAHSYVSDIFDIIEVLWAN----QQLIELILALLEEVSIVLDL
FRAP_Hsap EFKLYLPQLIPHMLRVF---MH-DN---SPGRI-VSIKLLAAIQLFGANLDDYLHLLLPP
FRAP_Mmus EFKLYLPQLIPHMLRVF---MH-DN---SQGRI-VSIKLLAAIQLFGANLDDYLHLLLPP
B0261.2_Cele DFSKYTGELIPYLLTVL---QT-DK---TKERV-LTVKVMESIQKLTHCIVQHLHLVLPP
TOR1_Scer EFKRLVPLTLTLFLVIL---EN-DK---SSDKV-LSRRVLRLLESFGPNLEGYSHLITPK
TOR2_Scer EFKRFVPETLTFFLDIL---EN-DQ---SNKRI-VPIRILKSLVTFGPNLEDYSHLIMPI
Tor_Ddis EFKVYLPNLIPQMLNVL---HT-DR---SPKRS-PTTKVLRALEVFGTNLDDYLHLVIPA
FRAP_Spur ------------------------------------------------------------
TOR_Dmel EFRDYLAELIPQILRVL---QH-DN---SKDRM-VTRRLLQALQKFGSTLGYYLPLILPP
CC1G_00894_Ccin EFKPFLPTILPLVLKVF---DG-DT---SDKRIAVQIKIFDAFLTFGANIEEYLHLVIPI
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe EFRMHMPEILPKCIQAL---NEAER---NADYA-YVASLLHTFEVFGASLDEHMHLVLPA
GK008_Glam SLGNYGSQFFLKFVGLFTVLKS-SQEISDSAKK-LLIRACRSVVALSSLFSNHIHLIVDL
FRAP_Hsap IVKLFD--APEAPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLDQ--S-------
FRAP_Mmus IVKLFD--APEVPLPSRKAALETVDRLTESLDFTDYASRIIHPIVRTLDQ--S-------
B0261.2_Cele LLIILD--DFSLKLSIRNTALSTVLHMTQQVDVSAYAPRMMQSWHHNIS---T-------
TOR1_Scer IVQMAE--FTS--GNLQRSAIITIGKLAKDVDLFEMSSRIVHSLLRVLSSTTS-------
TOR2_Scer VVRMTE--YSA--GSLKKISIITLGRLAKNINLSEMSSRIVQALVRILNNG-D-------
Tor_Ddis IVKLFE--QVDVTTQVRTLAIQTIGRLCKKLNFSDYASRIIHPLARVLDST-E-------
FRAP_Spur ------------------------------------------------------------
TOR_Dmel IVKLFD--SPYVPQQVSMVALETINNLACQLDFTDFSSRIIHPLVRVLDA--E-------
CC1G_00894_Ccin IVKSYE--RSDAPSSLRKRAIQTIDGLSRRVNFSDHASRIIHPMVRVLDGN-N-------
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe LVRLFKPDVSNAPMDIRRSTIKTFSRLLPCMQVTAHVSSLLHPLLSVLDGT-K-------
GK008_Glam LCSGIR--KQKLGKELRFALLDTLSRLTICTNLSRFGASIIHPILEVIMEADPCTSVEHN
FRAP_Hsap ------------PELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRINHQRYDVLIC
FRAP_Mmus ------------PELRSTAMDTLSSLVFQLGKKYQIFIPMVNKVLVRHRINHQRYDVLIC
B0261.2_Cele ------------AEMRDKLLLLLIEIIKQLGKFFDIFKRGVDQKLRDYNLDKSVHYEQYR
TOR1_Scer ------------DELSKVIMNTLSLLLIQMGTSFAIFIPVINEVLMKKHIQHTIYDDLTN
TOR2_Scer ------------RELTKATMNTLSLLLLQLGTDFVVFVPVINKALLRNRIQHSVYDQLVN
Tor_Ddis ------------SELREETLNTLCALVYQLGSDYAIFIPMVGKVLARREIQSTNYELLIS
FRAP_Spur ------------------------------------------------------------
TOR_Dmel ------------PELRDQAMTTLRSLAKQLGKKYLVFVPMVQRTLNKHRIVDPEYEELLS
CC1G_00894_Ccin ------------NELRMAVFDTLCSLVAQLGSDFAIFVPTINKATLRNRISHPRYENLVS
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe ------------DELRNDAVDAICVLATVLGAEFTMFLPSVRKLLQRHHLQHPQFDSIES
GK008_Glam KNANPEKGLNPMNIVSYKAFEVLHFICAQFGVSVTLYIPVITECLLKVGFTSGLLDSIFS
FRAP_Hsap RIVKGYTL-----ADEEE--------DP--------------------LIY---------
FRAP_Mmus RIVKGYTL-----ADEEE--------DP--------------------LIY---------
B0261.2_Cele KLAQRAQMSRDVLTSSVFAGS-----NG--------------------NIQYSSTQAGMR
TOR1_Scer RILNNDVL-----PTKILEAN-----TT--------------------------------
TOR2_Scer KLLNNECL-----PTNIIFDK-----EN--------------------------------
Tor_Ddis KLLKNQQL-----MLTPGSGD-----DG--------------------GMGANRFG----
FRAP_Spur ------------------------------------------------------------
TOR_Dmel KIKSCSTL-----ADSYGAG------ES--------------------ELRPS-------
CC1G_00894_Ccin KLLNGESL-----PSEAGGM------D---------------------WIQA--------
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe RLKRRDPILVDVRPTAVS--------EA--------------------DIAAS-------
GK008_Glam LLLRREEV-----DPVTFYRLICEWKKKQAKKFSEYTSLASLLAMYETPVTQDTLL----
FRAP_Hsap -----------------------------------Q--HRMLRS----GQGD--------
FRAP_Mmus -----------------------------------Q--HRMLRS----SQGD--------
B0261.2_Cele GQANNVYANNDLHERLMNGSIDSGASRQDNRDDYYRYGVEEKKEVPKVAPTT--------
TOR1_Scer -----------------------------------D-----YKP----------------
TOR2_Scer -----------------------------------------EVP----------------
Tor_Ddis --------G--------------------------D--HNGHHL----GEDH--------
FRAP_Spur ------------------------------------------------------------
TOR_Dmel -----------------------------------RF--KNN------------------
CC1G_00894_Ccin ---------------------------------------ENS------------------
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe -----------------------------------SHG----------------------
GK008_Glam --------Y--------------------------M--ESISNK----VPGDDKDAMILV
FRAP_Hsap -------------------------ALASGPVETGPMKKLHVSTI--------NLQKAWG
FRAP_Mmus -------------------------ALASGPVETGPMKKLHVSTI--------NLQKAWG
B0261.2_Cele -------------------------ARPTSELVTVQITKQRLNKD--------ALMPQWK
TOR1_Scer -------------------------AEQMEAAD-AGVAKLPINQS--------VLKSAWN
TOR2_Scer -------------------------ERKNYEDE-MQVTKLPVNQN--------ILKNAWY
Tor_Ddis -------------------------NNTSTPLD-IGVKKLKANEQ--------HLKNAWE
FRAP_Spur ------------------------------------------------------------
TOR_Dmel --------------------------EPFVTDRNSNNKNLQVTTN--------ELRTAWQ
CC1G_00894_Ccin --------------------------KAQEFQAPAEAPKMTVNQQ--------HLKQAWD
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe --------------------------AELDGENALSTRGTQV------------------
GK008_Glam VKDINFDDIGSVINYLHTSSTWFGDDMRPLPAGAIGVHSLSIQENDMLNKHVTIPQQIWR
FRAP_Hsap AARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELN
FRAP_Mmus AARRVSKDDWLEWLRRLSLELLKDSSSPSLRSCWALAQAYNPMARDLFNAAFVSCWSELN
B0261.2_Cele NENLTSKDEWLQWLMKIRIGFLTYGSSPSLRAASSLGDQHPHLARDLFPAAFMSVWTELD
TOR1_Scer SSQQRTKEDWQEWSKRLSIQLLKESPSHALRACSNLASMYYPLAKELFNTAFACVWTELY
TOR2_Scer CSQQKTKEDWQEWIRRLSIQLLKESPSACLRSCSSLVSVYYPLARELFNASFSSCWVELQ
Tor_Ddis TSQRSTKEDWGEWIRRFSVELLRESPSPALRSCLSLAQDYHPLVKELFNAGFVSCWTELH
FRAP_Spur ------------------------------------------------------------
TOR_Dmel VTRRVSKDDWVEWLKRLSIGLLKESPSHALRACRSLAQEYDTLLRDLFNAAFISCWTELS
CC1G_00894_Ccin VSQVTTKDDWLEWMHRLSVEFMKESPSHALRACMTLVDIHQPLAKELFNAAFLSCWTELY
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe --------------------------------------NEPHVARELFAVAFVSCWSQLN
GK008_Glam ADTCKKNEEWRHWLSNLSLTLLQCSPLKCLRACHKLATSYPRVARDLFNYSFLACLSETY
FRAP_Hsap E---DQQDELIRSIELALTSQDI-AEVTQTLLNLAEFMEHSDKG-PLPLRDDNGIVLLGE
FRAP_Mmus E---DQQDELIRSIELALTSQDI-AEVTQTLLNLAEFMEHSDKG-PLPLRDDNGIVLLGE
B0261.2_Cele S---DVQNDLTSCLLRAIS-TGI-PELIQTILNLAEFMDHSEKG-PLPISH----DVLGR
TOR1_Scer S---QYQEDLIGSLCIALSSPLNPPEIHQTLLNLVEFMEHDDK--ALPIPT----QSLGE
TOR2_Scer T---SYQEDLIQALCKALSSSENPPEIYQMLLNLVEFMEHDDK--PLPIPI----HTLGK
Tor_Ddis E---QFQEELVRSLETALLSPNIPPEILQTLLNLAEFMELHEK--PLPIDI----RTLGA
FRAP_Spur ------------------------------------------------------------
TOR_Dmel P---DLKNELTQSLIQALQVTDM-PEITQTILNLAEFMEHCDRD-PIPIET----KLLGT
CC1G_00894_Ccin D---QYQEDLVRSIEFAITSTTAPPELIHRLLNLAEFMEHEEK--PLPIEH----RTLGE
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe D---SYKKQLVRSLNYALTSPNIPSDILGTLLNLAEFMERDED--PLPVDT----RTLGS
GK008_Glam PSNNEHRNYIVESIRSVFLSQNCPLDVLQILLDLAEFWENRSREFSTTFSH----NFLGE
FRAP_Hsap RAAKCRAYAKALHYKELEFQKGPT-------------PAILESLISINNKLQQPEAAAGV
FRAP_Mmus RAAKCRAYAKALHYKELEFQKGPT-------------PAILESLISINNKLQQPEAASGV
B0261.2_Cele WAEQTKAFAKACRYKEMSVLKKSGSMQTTFTRKVKLEPNDCQSLITYANKLNVQEEAAGV
TOR1_Scer YAERCHAYAKALHYKEIKFIKEPE-------------NSTIESLISINNQLNQTDAAIGI
TOR2_Scer YAQKCHAFAKALHYKEVEFLEEPK-------------NSTIEALISINNQLHQTDSAIGI
Tor_Ddis LAEKCHAYAKALHYKESEFSQSPS--------------STIEALISINNQLQQPEAAIGI
FRAP_Spur ------------------------------------------------------------
TOR_Dmel RAMACRAYAKALRYKEEEFLLRED-------------SQVFESLILINNKLQQREAAEGL
CC1G_00894_Ccin YANKYMAYAKALHYKEMEYFAESS-------------PAVIESLISINTKLQQHDAAWGT
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe LAEKCHLFAKALHYKEMEFDMVLAREQ------KHQLVGAVEALIHVNNQLHQHEAAVGI
GK008_Glam VAERCHAYTRSLRYKETEYAQHPI-------------E-AVGRLIAINYSLGYEETAIGT
FRAP_Hsap LEYAMKHFG---------------------------------------------------
FRAP_Mmus LEYAMKHFG---------------------------------------------------
B0261.2_Cele VRYAERNEM---------------------------------------------------
TOR1_Scer LKHAQQHH----------------------------------------------------
TOR2_Scer LKHAQQHN----------------------------------------------------
Tor_Ddis LIYAQKNH----------------------------------------------------
FRAP_Spur ------------------------------------------------------------
TOR_Dmel LTRYRNAAN---------------------------------------------------
CC1G_00894_Ccin LLHAREQ-Y---------------------------------------------------
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe LTYAQRN-L---------------------------------------------------
GK008_Glam LRVECKRLNFISTNLIYDILLRCLYTGLDDVFTMMQREGGLEPGAAVNCSAESTLERIIN
FRAP_Hsap ------------------------------------------------------------
FRAP_Mmus ------------------------------------------------------------
B0261.2_Cele ------------------------------------------------------------
TOR1_Scer ------------------------------------------------------------
TOR2_Scer ------------------------------------------------------------
Tor_Ddis ------------------------------------------------------------
FRAP_Spur ------------------------------------------------------------
TOR_Dmel ------------------------------------------------------------
CC1G_00894_Ccin ------------------------------------------------------------
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe ------------------------------------------------------------
GK008_Glam KVVSKIVTKALTEAKKISNLNQSIPQQLVSYGSIGGIFVEGRPVMSGPEGSVLQVDYNEI
FRAP_Hsap -----------------------------------------------E-LEIQATWYEKL
FRAP_Mmus -----------------------------------------------E-LEIQATWYEKL
B0261.2_Cele -----------------------------------------------N-FQMRGRWYEKL
TOR1_Scer -----------------------------------------------S-LQLKETWFEKL
TOR2_Scer -----------------------------------------------E-LQLKETWYEKL
Tor_Ddis -----------------------------------------------S-VELKEGWYEKL
FRAP_Spur ------------------------------------------------------------
TOR_Dmel -----------------------------------------------E-LNVQGRWYEKL
CC1G_00894_Ccin -----------------------------------------------D-VTKHEEWYERL
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe -----------------------------------------------G-VQLKESWQVF-
GK008_Glam GIYLSALARRMLKSKLTYQYPTFLMYEENLFQSVLKTLRYKAQGHMQDLYGPSPKWFENV
FRAP_Hsap HEWEDALVAYDKKMDTNK-----------D-----------DPELMLGRMRCLEALGEWG
FRAP_Mmus HEWEDALVAYDKKMDTNK-----------E-----------DPELMLGRMRCLEALGEWG
B0261.2_Cele NEWEKALGAYELEEKKKSSCPNLQVYDEKDHLMTPEE-AATAEEARMHEMRCLEALGRWD
TOR1_Scer ERWEDALHAYNEREKAGD-----------T-----------SVSVTLGKMRSLHALGEWE
TOR2_Scer QRWEDALAAYNEKEAAGE-----------D-----------SVEVMMGKLRSLYALGEWE
Tor_Ddis RRWEDALAAYEKKQKDDPNG---------G-----------TIENTMGILRCLHALGEWE
FRAP_Spur ------------------------------------------------------------
TOR_Dmel HNWDEALEHYERNLKTDSS----------------------DLEARLGHMRCLEALGDWS
CC1G_00894_Ccin GRWQEALQVYDRKAMEDPD----------------------SPEVKIGRVKCYHALGEWE
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe ------------AVA---------------------T-HILQKIMVVGRMRCLVALARWE
GK008_Glam CLWDKALSGYNRQIDQLKLSLKSNT----S---EARTLLPMLVNLTKDKIRCLFALADYS
FRAP_Hsap QLHQQCCEKWTL-------------VNDETQ--------------AKMARMAAAAAWGLG
FRAP_Mmus QLHQQCCEKWTL-------------VNDETQ--------------AKMARMAAAAAWGLG
B0261.2_Cele ELNSKSV-VWADQRGNRNDSVRDEINKKQLD--------------HKMAVIAARGAWAVD
TOR1_Scer QLSQLAARKWKV-------------SKLQTK--------------KLIAPLAAGAAWGLG
TOR2_Scer ELSKLASEKWGT-------------AKPEVK--------------KAMAPLAA-AAWGLE
Tor_Ddis RLSALSSETWKSD------------INDHTR--------------ATIAPLAAAAAWNLV
FRAP_Spur ------------------------------------------------------------
TOR_Dmel ELSNVTKHEWEN-------------FGTEAK--------------SRAGPLAAVAAWGLQ
CC1G_00894_Ccin LLAAQVQENWAN-------------ATNEER--------------REMAPMAAAAAWSLN
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe ELSTLCRETWSE---------------PSAQ--------------LQMAPMAASAAWNMG
GK008_Glam AVQEEADQLLNY-------------LSSESKEEAGLTTVKHTLIKGFQADIATYAAWSLL
FRAP_Hsap QWDS--MEEYTCMIPRDT---------------HDGAFYRAVLALHQDLFSLAQQCIDKA
FRAP_Mmus QWDS--MEEYTCMIPRDT---------------HDGAFYRAVLALHQDLFSLAQQCIDKA
B0261.2_Cele NWER--MADYVSVISENT---------------QDGAMLRAVVAVHNDENTKAMGLIEKV
TOR1_Scer EWDM--LEQYISVMKPKS---------------PDKEFFDAILYLHKNDYDNASKHILNA
TOR2_Scer QWDE--IAQYTSVMKSQS---------------PDKEFYDAILCLHRNNFKKAEVHIFNA
Tor_Ddis NWDK--MDEYVCAMNKDT---------------VEGSFYRAILEVHHDNFTLAHGFIDHA
FRAP_Spur ------------------------------------------------------------
TOR_Dmel DWEA--MREYVRCIPEDT---------------QDGSYYRAVLAVHHDDFETAQRLIDET
CC1G_00894_Ccin DWDS--MDNYIGTMKNDS---------------PDRAFYRAILSVHQNQFSKALAHIAKA
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe EWDE--MEEYVSQMDNGDEMNVPTRGQDGTGTGFAGAFFRAVLCIRRSKYDEAGIYAERA
GK008_Glam EQDQEDVEIWLRVLPEDN---------------IDGTIIRATSYIKANKMLEAHKLLCKL
FRAP_Hsap RDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLV-------------------
FRAP_Mmus RDLLDAELTAMAGESYSRAYGAMVSCHMLSELEEVIQYKLV-------------------
B0261.2_Cele REMIDSELTAMANESYERAYIPMVSVQQMAELEEAIEYKTRP------------------
TOR1_Scer RDLLVTEISALINESYNRAYSVIVRTQIITEFEEIIKYKQLPP-----------------
TOR2_Scer RDLLVTELSALVNESYNRAYNVVVRAQIIAELEEIIKYKKLPQ-----------------
Tor_Ddis RTLVDTELTALLGESYNRAYKVVVRLQQLSELEEIIEYKKCVD-----------------
FRAP_Spur ------------------------------------------------------------
TOR_Dmel RDLLDTELTSMAGESYERAYGAMVCVQMLAELEEVIQYKLIP------------------
CC1G_00894_Ccin RELIDPELSSFTGEGYGRSYNVMVRAQMLSELEEIIAYKQYA------------------
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe RKCLATELAALVLESYDRAYSNMVRVQQLAELEEVIEYCTLQTGN---------------
GK008_Glam RLRIDPDLIGLSAESYTRAYNLCILLQTITELQNIISYKLALNGLKLDAPSTLIKEGGNP
FRAP_Hsap -------------------PERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHED
FRAP_Mmus -------------------PERREIIRQIWWERLQGCQRIVEDWQKILMVRSLVVSPHED
B0261.2_Cele --------------------ERRPRIALLWSRRLQGCRRNVEQWQRLIMLRGLVLSPQEM
TOR1_Scer ------------------NSEKKLHYQNLWTKRLLGCQKNVDLWQRVLRVRSLVIKPKQD
TOR2_Scer ------------------NSDKRLTMRETWNTRLLGCQKNIDVWQRILRVRSLVIKPKED
Tor_Ddis ------------------SPERRNMIKNTWKTRLRGCQHNVDIWQSILAVHSLVISPHEE
FRAP_Spur ------------------------------------------------------------
TOR_Dmel --------------------ERREPLKTMWWKRLQGGQRLVEDWRRIIQVHSLVVKPHED
CC1G_00894_Ccin --------------------DQPERQAT-MRKTLQGCQPDVEVWQRILQVRTLVSSPEQD
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe ---------------P-ASEARASLIRRMWRDRIRGAKRNVEVWQRLLSVRTLVLPPTED
GK008_Glam YENIFETTLISFNPPPGFADTEKERLRLMWSRKISMIRWDCESWEALLRVRRLIIFPIED
FRAP_Hsap MRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSR--------------------------
FRAP_Mmus MRTWLKYASLCGKSGRLALAHKTLVLLLGVDPSR--------------------------
B0261.2_Cele HPLRVKFSSMCRKQGKNSMSRAVLRELLSLPANS--------------------------
TOR1_Scer LQIWIKFANLCRKSGRMRLANKALNMLLEGGND------------------------P--
TOR2_Scer AQVRIKFANLCRKSGRMALAKKVLNTLLEETDD------------------------P--
Tor_Ddis LDMWLKFVGLCRKGSRLGLAQKTLTMLMGKDPST-----------------------T--
FRAP_Spur ------------------------------------------------------------
TOR_Dmel IHTWLKYASLCRKSGSLHLSHKTLVMLLGTDPKL--------------------------
CC1G_00894_Ccin PVMWIKFANLCRKNDRMMLAEKTINSLLTPERRM-----------------------L--
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe AETWLKFASLCYKSGRYD-------------PEQ-----------------------S--
GK008_Glam QEVWIRFSVLCLQSGRVQLARKTLETFINSSSVHHIKVSKSRGLYTLLGLTSFGTPRRYL
FRAP_Hsap ------------------------------------------------------------
FRAP_Mmus ------------------------------------------------------------
B0261.2_Cele ------------------------------------------------------------
TOR1_Scer ------------------------------------------------------------
TOR2_Scer ------------------------------------------------------------
Tor_Ddis ------------------------------------------------------------
FRAP_Spur ------------------------------------------------------------
TOR_Dmel ------------------------------------------------------------
CC1G_00894_Ccin ------------------------------------------------------------
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe ------------------------------------------------------------
GK008_Glam KHGSGDVSTGGSVTPIGSALGAEMGVVQDLSAVGSSLAKYLLKDGVVKDAFTAQQHVALP
FRAP_Hsap ---------------------------------------------------------QLD
FRAP_Mmus ---------------------------------------------------------QLD
B0261.2_Cele --------------------------------------------------------DLVR
TOR1_Scer --------------------------------------------------------S--L
TOR2_Scer --------------------------------------------------------D--H
Tor_Ddis --------------------------------------------------------SQFG
FRAP_Spur ------------------------------------------------------------
TOR_Dmel --------------------------------------------------------N-PN
CC1G_00894_Ccin --------------------------------------------------------DHHH
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe ----------------------------------------------------------DP
GK008_Glam TSDVLSIASHSVAKPTLQMIANASTHQGQSIEKETPLSIVGQQCDDAKRNAQRDLFNALI
FRAP_Hsap HPLPTVHPQVTYAYMKNMWKSAR---KIDAFQHMQHFVQ--TMQQQAQ--------HAI-
FRAP_Mmus HPLPTAHPQVTYAYMKNMWKSAR---KIDAFQHMQHFVQ--TMQQQAQ--------HAI-
B0261.2_Cele AKAPFDKPLLVLALAKQLYQDDH---KDEAIRALEDLAN--HWNKRINPIPKATGR----
TOR1_Scer PNTFKAPPPVVYAQLKYIWATGA---YKEALNHLIGFTS--RLAHDLGLDPNNMIAQSVK
TOR2_Scer PNTAKASPPVVYAQLKYLWATGL---QDEALKQLINFTS--RMAHDLGLDPNNMIAQSVP
Tor_Ddis SVLPNTHPRITFAYIKQLWSAGA---KQPAFEKLRTFVQ--ALRDT--------------
FRAP_Spur ------------------------------------------------------------
TOR_Dmel QPLPCNQPQVTYAYTKYMAANNQ---LQEAYEQLTHFVS--TYSQELSCLPPE-------
CC1G_00894_Ccin HHNTKAPPNVVYAQLKYMWANGE---KEETLNHLRLFTA--SLAKDIQQETNEQGHR---
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe PPGYVVNPPVMLAYLKYLWSFGEESKRQTAYRRLQYLAL--DLANGQAS----MYCT---
GK008_Glam PPLNHVYPHVLYAYCKHLWVSSN----ENVLEKLVAFTHLIRLCNDVSI-----------
FRAP_Hsap --ATEDQQHKQELHKLMARCFLKLGEWQLNLQG-I-------------------------
FRAP_Mmus --ATEDQQHKQELHKLMARCFLKLGEWQLNLQG-I-------------------------
B0261.2_Cele ---ELIPPSTKEPARICAKVLLKLGEWTELKSKTSNNMQVGELSFVRQQVSPQYRTKESR
TOR1_Scer LSSASTAPYVEEYTKLLARCFLKQGEWRIATQPNW-------------------------
TOR2_Scer QQSKRVPRHVEDYTKLLARCFLKQGEWRVCLQPKW-------------------------
Tor_Ddis -----------DDLPLQGRAYLKLGEWQLALGDTL-------------------------
FRAP_Spur ------------------------------------------------------------
TOR_Dmel -------ALKQQDQRLMARCYLRMATWQNKLQDSI-------------------------
CC1G_00894_Ccin --PNVSKSKLAELTKLLARCYFKQGEWQMELKDDW-------------------------
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe --PQGA--SGS-------------------------------------------------
GK008_Glam ---------QKTEPKLVCRMLIRLGAWYSDLLTPL-------------------------
FRAP_Hsap NES--TIP----------------------------------------------------
FRAP_Mmus NES--TIP----------------------------------------------------
B0261.2_Cele TPETIAFE----------------------------------------------------
TOR1_Scer RNT--NPD----------------------------------------------------
TOR2_Scer RLS--NPD----------------------------------------------------
Tor_Ddis SEA--SIP----------------------------------------------------
FRAP_Spur ------------------------------------------------------------
TOR_Dmel RPD--AIQ----------------------------------------------------
CC1G_00894_Ccin DAR--NVE----------------------------------------------------
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe ------------------------------------------------------------
GK008_Glam DHK--SCSMIGTISPSEGYVNIPVQDTVTSCSAIWNSIVNNCDADASVCSTTYEATEHSA
FRAP_Hsap --------------------------------------------------KVLQYYSAAT
FRAP_Mmus --------------------------------------------------KVLQYYSAAT
B0261.2_Cele --------------------------------------------------NTINYYQQAT
TOR1_Scer --------------------------------------------------AILGSYLLAT
TOR2_Scer --------------------------------------------------SILGSYLLAT
Tor_Ddis --------------------------------------------------HIISSFKAAT
FRAP_Spur ------------------------------------------------------------
TOR_Dmel --------------------------------------------------GALECFEKAT
CC1G_00894_Ccin --------------------------------------------------DILHSYYYAT
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe ------------------------------------------------------SGVSPV
GK008_Glam ERLELSSASTLDKAVAKLVDNILLAYDELSNVSLEECNQYNTVGMSRIGLIALEWFQVAA
FRAP_Hsap EHDRSWYKAWHAWAVMNFEAVLHYKHQNQ-ARDEKKKLRHASGANITNATTAATTAATAT
FRAP_Mmus EHDRSWYKAWHAWAVMNFEAVLHYKHQNQ-ARDEKKKLRHASGANITNATTAATTAASAA
B0261.2_Cele QYDPGWHKVWHKLASTHFYAVCRERPHPTTVISPPQQPQQPKKMHIPPVTRATSPPPPAQ
TOR1_Scer HFDKNWYKAWHNWALANFEVISMVQEETK-LNGGKNDDDDDTAVNNDN----------VR
TOR2_Scer HFDNTWYKAWHNWALANFEVISMLTSVSK----KKQEGSDASSVTDIN-----------E
Tor_Ddis ECDPNWYKAWHSWALINFEVVSHYEQNGG-T-----------------------------
FRAP_Spur ------------------------------------------------------------
TOR_Dmel SYDPNWYKAWHLWAYMNFKVVQAQKSA----LDKQQPPGASMGMTM--------------
CC1G_00894_Ccin HYDPGWYKAWHTWALANFEVISHIDTLAE--NRATDIPGDSLASHV--------------
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe PLIAPWGKAWHRWALFNTAALSHYSMKG----DS--------------------------
GK008_Glam DRDETSNHIWKCISHTTYAIVNSFAAYID-KL--NDRPGVDGG------LQIVTRRSSVD
FRAP_Hsap TTASTE--GSNSESEAESTENSPTPS----P-------------------------L--Q
FRAP_Mmus AATSTE--GSNSESEAESNENSPTPS----P-------------------------L--Q
B0261.2_Cele KSPQPAPFHSITEPL-SVIIDYPVPPPLGSLVGLPPMPAYLSSNSSLPPQHHHVSPLSND
TOR1_Scer IDGSIL--GSG-------------------S-------------------------L--T
TOR2_Scer FDNGMI--GVN-------------------T-------------------------F--D
Tor_Ddis ------------------------------------------------------------
FRAP_Spur ------------------------------------------------------------
TOR_Dmel --------GS--------------------------------------------------
CC1G_00894_Ccin --------VQ---------------------------------------------A----
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe ------------------------------------------------------------
GK008_Glam ATSDAV--GSTSEALSQSVQDSDRPLVC--P---EH--------------------L--G
FRAP_Hsap --KKVTEDLSKTLLMYTVPAVQGFFRSISLSRG-----NNLQDTLRVLTLWFDYGHWP--
FRAP_Mmus --KKVTEDLSKTLLLYTVPAVQGFFRSISLSRG-----NNLQDTLRVLTLWFDYGHWP--
B0261.2_Cele --SPSNSAENKLYLKHAAHAVRCFAKALMCSP-----GSRLEDTLRLMQLWFDHGDDKDQ
TOR1_Scer --INGNRYPLELIQRHVVPAIKGFFHSISLLET-----SCLQDTLRLLTLLFNFGGIK--
TOR2_Scer --AKEVHYSSNLIHRHVIPAIKGFFHSISLSES-----SSLQDALRLLTLWFTFGGIP--
Tor_Ddis ---------PEQIGAHLLPAVHSFFKSISLGPD-----RSLQDTLRLLTLWFKHGAQK--
FRAP_Spur ------------------------------------------------------------
TOR_Dmel ----GLDSDLMIIQRYAVPAVQGFFRSISLIK-----GNSLQDTLRLLTLWFDYGNHA--
CC1G_00894_Ccin ---VTGKPPFVAVLDAMLILGKGFFRSISLRN-----QDALQDTLRLLTLWFKYGHHD--
AqueK046_Aque -------------------------------------------TNRLLTLWFDYGHIS--
FRAP_Smoe ----------VKAAHHVVSAVSGYFKSIANASTNKGGDDSLQDILRLLTLWFNHGASD--
GK008_Glam FVQNRQVLLEKAKLEYLVESIIAHFKCIETGRS----IEALPTTLRLMTLWFRYGSYD--
FRAP_Hsap DVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPL-VGRLIHQLLTDIGRYHPQALIYPL
FRAP_Mmus DVNEALVEGVKAIQIDTWLQVIPQLIARIDTPRPL-VGRLIHQLLTDIGRYHPQALIYPL
B0261.2_Cele DVYFALTETIFDLPVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIYAL
TOR1_Scer EVSQAMYEGFNLMKIENWLEVLPQLISRIHQPDPT-VSNSLLSLLSDLGKAHPQALVYPL
TOR2_Scer EATQAMHEGFNLIQIGTWLEVLPQLISRIHQPNQI-VSRSLLSLLSDLGKAHPQALVYPL
Tor_Ddis EVEAALMQGFNTISIDTWLHVIPQIIARIHAPVLP-VRRLLHELIDTIGKEHPQALVYPL
FRAP_Spur ------------------------------------------------------------
TOR_Dmel EVYEALLSGMKLIEINTWLQVIPQLIARIDTHRQL-VGQLIHQLLMDIGKNHPQALVYPL
CC1G_00894_Ccin EVSHSMANGFSTVEVDTWLEVIPQIIARIQTPHAN-IRRNINNLLTDVGKHHPQALIYPL
AqueK046_Aque EVHEALEEGIKTVDIENWLQVIPQLIARIDSPRRL-VSKLIHELLTDVGRHHPQALIYPL
FRAP_Smoe EVYAALQDGFKHVIIDTWLVVLPQIIARIHSHIPA-VRELIQQLLVRIGQIHPQALMYPL
GK008_Glam EVETEIINGLAAVPINIWLDVIPQLIARLHSPQHK-IRLLVHQLLVLIGTEHPQALIYPL
FRAP_Hsap TVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASR
FRAP_Mmus TVASKSTTTARHNAANKILKNMCEHSNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASR
B0261.2_Cele TVASRSKDVHRSKNAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASR
TOR1_Scer TVAIKSESVSRQKAALSIIEKIRIHSPVLVNQAELVSHELIRVAVLWHELWYEGLEDASR
TOR2_Scer MVAIKSESLSRQKAALSIIEKMRIHSPVLVDQAELVSHELIRMAVLWHEQWYEGLDDASR
Tor_Ddis TVATKSHSPARLAAAKSLMDKMRKHSATLVDQALPVSQELVRTAILWLEMWYEGLEEASR
FRAP_Spur ------------------------------------------------------------
TOR_Dmel TVASKSASLARRNAAFKILDSMRKHSPTLVEQAVMCSEELIRVAILWHEQWHEGLEEASR
CC1G_00894_Ccin TVASKSSSSARRTAAIQIMERMKDHSSTIVTQALLVSKELIRVAILWHEMWHEGLEEASR
AqueK046_Aque TVAAKSQSTVRRDAADMILSNMREHSSDLVQQAVMVSEELIRVAILWHEQWHETLEDASR
FRAP_Smoe LVACKSISSSRKTAALTVVDRVRQHHVALVEQAQLVSQELIRVAILWHEMWYEALEEASR
GK008_Glam VVASKSTILNRRVESLSIVDQIRRTNEAMILESLNINKELQRVAILWPEIAYDLITQAST
FRAP_Hsap LYFG----E-RNVKGMFEVLEPLHAMME-RG-PQTLKETSFNQAYGRDLMEAQEWCRKYM
FRAP_Mmus LYFG----E-RNVKGMFEVLEPLHAMME-RG-PQTLKETSFNQAYGRDLMEAQEWCRKYM
B0261.2_Cele VYFHRRLQD-NNVQAMFDALRNMNDLMQ-KGAPTTMKEHSFQQTYSSDLKEAGRYVQAFE
TOR1_Scer QFFV----E-HNIEKMFSTLEPLHKHLG-NE-PQTLSEVSFQKSFGRDLNDAYEWLNNYK
TOR2_Scer QFFG----E-HNTEKMFAALEPLYEMLK-RG-PETLREISFQNSFGRDLNDAYEWLMNYK
Tor_Ddis QYFG----D-HNPEAMLATLAPLHQILE-KG-PETTSETSFLQAFGRDLQEALEWSKKYE
FRAP_Spur ----------------------------------------FH------------------
TOR_Dmel LYFG----D-RNVKGMFEILEPLHAMLE-RG-PQTLKETSFSQAYGRELTEAYEWSQRYK
CC1G_00894_Ccin LYFN----D-KNPEGMIMALEPLHKLLE-KG-PTTARETSFAQVFGRELAEAREACKRYQ
AqueK046_Aque MYFG----E-HNVQGMFKVLDPLHQKLD-KG-PETLKEISFNHVS---------------
FRAP_Smoe LYFG----E-HNKEGMLNVLEPLHRKLEEEG-AVTLKEIAF--AYGRELQEAHEWCMEYR
GK008_Glam AFCE----EPRDLVKFFNYACQLQLLAS-RT-PETQSESVFIQMFSSQLQAAWDSCRQFP
*
FRAP_Hsap KSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDP-N-
FRAP_Mmus KSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYDP-N-
B0261.2_Cele SSGNVKDLNQAWEIYCSVFKKLRDQLATLNSLDLVYVSPNLVSAKDLELVVPGTYDP-S-
TOR1_Scer KSKDINNLNQAWDIYYNVFRKITRQIPQLQTLDLQHVSPQLLATHDLELAVPGTYFP-G-
TOR2_Scer KSKDVSNLNQAWDIYYNVFRKIGKQLPQLQTLELQHVSPKLLSAHDLELAVPGTRASGG-
Tor_Ddis KTRKEGDLNQAWDLYYQVFRRIYKQLPQMSSLELQYVSPKLLNSNNMELAVPGTYKA-S-
FRAP_Spur ------------------------------------------------------------
TOR_Dmel TSAVVMDLDRAWDIYYHVFQKISRQLPQLTSLELPYVSPKLMTCKDLELAVPGSYNP-G-
CC1G_00894_Ccin IYGDPTELDKAWDIYYGVFKKVEKQLPSLTTLDLQYVSPSLLKARHLDLAVPGTYQS-G-
AqueK046_Aque --------------------------------------LF--------------------
FRAP_Smoe RTGNEAELTQAWDLYYHVFKRINKQLPSVTTLELQYVSPALLNARNLELAVPGTYRP-GP
GK008_Glam VTNDLVCLNIVMKHYKEIYDRIHSELPFLNTIDLLQTSPLLYNISNTNLCVPGSYHP-A-
FRAP_Hsap -QPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVN
FRAP_Mmus -QPIIRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVN
B0261.2_Cele -APIVSIQSFSSKMNVITSKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVN
TOR1_Scer -KPTIRIAKFEPLFSVISSKQRPRKFSIKGSDGKDYKYVLKGHEDIRQDSLVMQLFGLVN
TOR2_Scer -KPIVKISKFEPVFSVISSKQRPRKFCIKGSDGKDYKYVLKGHEDIRQDSLVMQLFGLVN
Tor_Ddis -ENVIRIQSFSQALSVIPSKQRPRKLTIIGSDGLEYTFLLKGHEDLRQDERVMQLFSLVN
FRAP_Spur ------------------------------------------------------------
TOR_Dmel -QELIRISIIKTNLQVITSKQRPRKLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVN
CC1G_00894_Ccin -RPVITIASFATKLTVIASKQRPRRLSLKGSDGRDYQYVLKGHEDLRQDERVMQLFSLVN
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe EANVVTIQSFDPQLIVMPSKQRPRKCTIKGSDGQDYTFLLKGHEDLRQDERVMQLFGLVN
GK008_Glam -RAITTIVKFYQKVFVIRSKQRPRKVGLVASDGEYYAFLLKGHEDLRQDERVMQLFTLIN
FRAP_Hsap TLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKK-KILLNIEH
FRAP_Mmus TLLANDPTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKK-KILLNIEH
B0261.2_Cele TLLANNSETCRRNLTIQRYSIVALSKDSGLIGWVPNCDTLHTLVKEYREKKAKIPLSIEH
TOR1_Scer TLLKNDSECFKRHLDIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHRDAK-KIPLNIEH
TOR2_Scer TLLQNDAECFRRHLDIQQYPAIPLSPKSGLLGWVPNSDTFHVLIREHREAK-KIPLNIEH
Tor_Ddis NLLSANHETAKSHLSIRRFSVIPLSPNSGLIGWVPHSDTLHTLIKDFRDSN-KILLSIEH
FRAP_Spur ------------------------------------------------------------
TOR_Dmel TLLLDDPDTFRRNLAIQRYAVIPLSTNSGLIGWVPHCDTLHTLIRDYRDKK-KVPLNQEH
CC1G_00894_Ccin TLLSVDTNSFKRRLHIQRYPVIPLAPNAGLLGWVQDSDTLHVLIRDYRESR-KVLLNIEY
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe TLLTNARHTAEKDLSIQRYDVVPLSPNSGLIGWVPNCDTLHHLIREYRDAR-KVPVNAEH
GK008_Glam NLLMNDSYCSRRGLMVMKYPITPLSQNSGLLYWVPGCDTIISLIKEFRQLK-RIHLETEM
FRAP_Hsap RIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLA
FRAP_Mmus RIMLRMAPDYDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLA
B0261.2_Cele KTLQKLSLETEHLTLMQKLQLFESALSVTQGEDLRHVLWLKSPSSEVWFDRRTNYTRSVA
TOR1_Scer WVMLQMAPDYENLTLLQKIEVFTYALDNTKGQDLYKILWLKSRSSETWLERRTTYTRSLA
TOR2_Scer WVMLQMAPDYDNLTLLQKVEVFTYALNNTEGQDLYKVLWLKSRSSETWLERRTTYTRSLA
Tor_Ddis RLMLQMCSDYDNLTLLQKVEVFQYALENSNGLDLHKVLWLKSRNSEVWLDRRTNYTRSLA
FRAP_Spur ------------------------------------------------------------
TOR_Dmel RTMLNFAPDYDHLTLMQKVEVFEHALGQTQGDDLAKLLWLKSPSSELWFERRNNYTRSLA
CC1G_00894_Ccin RLMLQMAPDYENLMLLQKVEVFEYALENTTGQDLYRVLWLKSTNSEHWLERRATYTRSLA
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe RAMVSFAPDLDHLTLIAKVEVFQHALEATDGDDLAKVFWLKSKTSEVWLERRTNYTRSLA
GK008_Glam QQIKYRAPAFMNMALHYKVDAFKYMLTTSDAIDLCRSLWNKASSAEDWLLKRMNYTRSIA
FRAP_Hsap VMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTN
FRAP_Mmus VMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTN
B0261.2_Cele CMSMVGYILGLGDRHPSNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLIN
TOR1_Scer VMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKYPEKVPFRLTRMLTY
TOR2_Scer VMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKFPEKVPFRLTRMLTY
Tor_Ddis VMSMVGYILGLGDRHPSNLMLDRHTGHILHIDFGDCFEVAMHRDKYPEKIPFRLTRMLIN
FRAP_Spur -------------------------GVI--------------------------------
TOR_Dmel VMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLIK
CC1G_00894_Ccin VNSMVGHILGLGDRHPSNLLLERSTGKVVHIDFGDCFEVAMHREKFPEKVPFRLTRMLTH
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe VMSMVGYLLGLGDRHPSNLMLNRYSGKILHIDFGDCFEAAMTREKFPEKVPFRLTRMLVK
GK008_Glam VSSIVGYILGLGDRHPANLMIERTTGMVLHIDYGDCFEVAMHREQLPEKVPFRLTSIMMK
FRAP_Hsap AMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNT-KGNKRSRT
FRAP_Mmus AMEVTGLDGNYRTTCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNT-KGNKRSRT
B0261.2_Cele AMEVTGLDGVYNYTAERVLKMLRTNQESLLAVLEAFVYDPVINWRLVEGMK-KDPKTRK-
TOR1_Scer AMEVSGIEGSFRITCENVMRVLRDNKESLMAILEAFALDPLIHWGFDLPPQ-KLTEQTGI
TOR2_Scer AMEVSGIEGSFRITCENVMKVLRDNKGSLMAILEAFAFDPLINWGFDLPTK-KIEEETGI
Tor_Ddis AMEVSGIEGNFRLTCEAVMNVLRNNKESLMAVLEAFVHDPLINWRLLTPNE-NNTKHKAT
FRAP_Spur ------------------------------------------------------------
TOR_Dmel AMEVTGIEGTYRRTCESVMLVLRRNKDSLMAVLEAFVYDPLLNWRLLDVDK-KGNDAVA-
CC1G_00894_Ccin AMEVSGIEGSFRNTCEITMTVLRDNKESLMAVLEAFVYDPLINWRLMQADV-EVRRPDA-
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe AMEVSGIEGNFRSICEDVMHVLRSNKDSVMAMMEAFVHDPLINWRLFNIND-VPASMATI
GK008_Glam AFESCGTEGSFRMTGEATMSILRSNKDSLVSVLETFIYDPLMSMKVLSGENTMGGKEN-I
FRAP_Hsap RTDSY--SA-G--QSVEILD--------GVELGEPAHK-KTGTTVPE-------------
FRAP_Mmus RTDSY--SA-G--QSVEILD--------GVELGEPAHK-KAGTTVPE-------------
B0261.2_Cele DTGG-RQNMAGAV--------------------LPS------------------------
TOR1_Scer PLPLI--NP--------------------SEL------LRKGAITVE-------------
TOR2_Scer QLPVM--NA--------------------NEL------LSNGAITEE-------------
Tor_Ddis NIASN--NS-TS-NSTTKIEGDLNTIDNPINKESPDHEAVAGSLKSSPVHGRQIARNQRV
FRAP_Spur ------------------------------------------------------------
TOR_Dmel GAGA-PGGRGGSGMQDSLSN--------SVEDSLPMAK-SK--PYDP-------------
CC1G_00894_Ccin DVER----VPEL-------G--------RV-AAHPQAP-NRKLKADE-------------
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe RAQTATQNLEAVG--------------------LPSPP-QRGARERE-------------
GK008_Glam --DGN--TE-FY-----------------------------GTR----------------
FRAP_Hsap SIHS--FIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSH-D-----DTLDVPTQVELLI
FRAP_Mmus SIHS--FIGDGLVKPEALNKKAIQIINRVRDKLTGRDFSH-D-----DTLDVPTQVELLI
B0261.2_Cele ------------------SSTTDSIMETIKRKLDGTEFVHTDGSTPPEPLQVTEQLAMLT
TOR1_Scer E--A--ANMEAEQQNETKNARAMLVLRRITDKLTGNDIKR-F-----NELDVPEQVDKLI
TOR2_Scer E--V--QRVENEHKNAIRNARAMLVLKRITDKLTGNDIRR-F-----NDLDVPEQVDKLI
Tor_Ddis GVDA--EQVEAEIVPEALNERALSVINRVNKKLTGRDFSS-N-----ETLDVPEQVQKLI
FRAP_Spur ------------------------------------------------------------
TOR_Dmel ---TLQQGGLHNNVADETNSKASQVIKRVKCKLTGTDFQTE------KSVNEQSQVELLI
CC1G_00894_Ccin N-DIFNETEEEPGAQEVRNERALFVYNRVQHKLTGRDFNPT------QVLSVKAQVEKLI
AqueK046_Aque ------------------------------------------------------------
FRAP_Smoe MLHAFNVVGQLGDANEVLNERAVSVMGRMSDKLTGRDFPVGE-----SVLSVKDQVQKLI
GK008_Glam ---R--PVQESYLEGNERNPKAVKIVQRIYDKLTGYDIKYID-----RSLSVSEQIQSLI
FRAP_Hsap KQATSHENLCQCYIGWCPFW
FRAP_Mmus KQATSHENLCQCYIGWCPFW
B0261.2_Cele EQATSPLNLCQSYIGWCPFW
TOR1_Scer QQATSIERLCQHYIGWCPFW
TOR2_Scer QQATSVENLCQHYIGWCPFW
Tor_Ddis DQATSHENLCLSYVGWCPFW
FRAP_Spur --------------VHYVVF
TOR_Dmel QQATNNENLCQCYIGWCPFW
CC1G_00894_Ccin EQATSLENLCQCFSGWCAFW
AqueK046_Aque ---------------LLCLY
FRAP_Smoe DQATSSENLCQSYVGWCPFW
GK008_Glam HSATNAENLCQLYIGWCPYW
: