IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    MAKVFLLS--------------------------------AL-L----------------
IRAK-0_bs_Smoe    MALLSL-----------------------------------L------------------
IRAK-0_t-2_Smoe   MASKGKLC--------------------------------FI-VS---------------
IRAK-0_as_Smoe    MAVEILF-------------------------F--------C------------------
IRAK-0_aq-2_Smoe  MEGTL--S---------SE-----LS-----RGTFVFGLHLWVLI---------------
IRAK-0_af-2_Smoe  MIGTHLFLL-------PHPFSLFPMA-----RA------LMF------------------
IRAK-0_af-1_Smoe  MIGTHLFLL-------PHPFSLFPMA-----RA------LMF------------------
IRAK-0_e-2_Smoe   MIYGREGNI-------GLE-----MS-----CL------WWV------------------
IRAK-0_bn_Smoe    MKTHSITTE---------------IT-----VG--------S------------------
IRAK-0_be_Smoe    MLVAGLIV----------------------------------------------------
IRAK-0_bm_Smoe    MMHSITC---------------------------------L-------------------
IRAK-0_ar-1_Smoe  MQPKRKCRV-------LTT-----DS-----RM--------L------------------
IRAK-0_bh_Smoe    MQTARTKPV---------------NS-----SSD-----FSY------------------
IRAK-0_x_Smoe     MQVLCWGN--------------------------------SV------------------
IRAK-0_n-1_Smoe   MSAYGRS---------------------------------RR------------------
IRAK-0_am_Smoe    MTYNV-P-----------------------------------------------------
IRAK-0_g-1_Smoe   MVFFH-I--------------------------------SLF------------------
IRAK-0_au-1_Smoe  MWRSVSWL---------------------------------S------------------
IRAK-0_au-2_Smoe  MWRSVSWL---------------------------------S------------------
IRAK-0_h_Smoe     MYLAS-------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   MSAYGRS---------------------------------RR------------------
IRAK-0_a-1_Smoe   MEYRLVAG--------------------------------DK-F----------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    MRALLESP--------------------------------PD-H----------------
IRAK-0_ba_Smoe    MGGSGMLN---------SQ-----LS-----KPTGFFGLRLWVVI---------------
IRAK-0_b-1_Smoe   VRTK--------------------------------------------------------
IRAK-0_c-2_Smoe   MAGGGYLT---------NQ-----LS-----RRTVIFGFKLWVVL---------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    MKVTFLL-----------------------------------------------------
IRAK-0_bg_Smoe    MGVLN------------DK-----LS-----EKTSLFGLKVWVVL---------------
IRAK-0_t-1_Smoe   MASRELY---------------------------------FL-VS---------------
IRAK-0_b-2_Smoe   NDLNSFT-----------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  MEGTL--S---------SE-----LS-----RGTFVFGLHLWVLI---------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    MWW---------------------------------------------------------
IRAK-0_c-1_Smoe   MAGGGYLT---------NQ-----LS-----RRTVIFGFKLWVVL---------------
IRAK-0_ac_Smoe    FCSYRTVGINKLSGPLPSS-----LG-----RL---------------------------
IRAK-0_z-2_Smoe   MPLSLW-----------------------------------I------------------
IRAK-0_k_Smoe     MLAPKNLS--------------------------------FA-MI---------------
IRAK-0_y-1_Smoe   MVLQVTFEQ-------------------------------II-VISRSMKNVISVVRIQR
IRAK-0_z-1_Smoe   MPLSLS-----------------------------------I------------------
IRAK-0_bq_Smoe    MANHP-L--------------------------------PLV------------------
IRAK-0_aj_Smoe    MADHPPL--------------------------------SLD------------------
IRAK-0_br_Smoe    MRGLPIA---------------------------------TI------------------
IRAK-0_l_Smoe     MRSGSYTV--------------------------------HL-HF---------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    MAKVFLLS--------------------------------AL-L----------------
IRAK-0_bk_Smoe    MERRAVA-----------------------------------------------------
IRAK-0_g-2_Smoe   MVFFH-I--------------------------------SLF------------------
IRAK-0_a-2_Smoe   MPWAARRL--------------------------------KL-FV---------------
IRAK-0_d-2_Smoe   GFLSLDCGA---------------NASYTDPATG-----IR-------------------
IRAK-0_y-2_Smoe   MLILHIQSD--------------------------------N---STG------------
IRAK-0_m-1_Smoe   MKTTLGIT--------------------------------A-------------------
IRAK-0_f_Smoe     FCSYRTVGINKLSGPLPSS-----LG-----RL---------------------------
IRAK-0_ar-2_Smoe  MQPKRKCRV-------LTT-----DS-----RM--------L------------------
IRAK-0_e-1_Smoe   MIYGREGNI-------GLE-----MS-----CL------WWV------------------
IRAK-0_d-1_Smoe   GFLSLDCGA---------------NASYTDPATG-----IR-------------------
IRAK-0_m-2_Smoe   MEFLKLLK--------------------------------CM-LD---------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    ------------------------------------------------------------
IRAK-0_t-2_Smoe   ------------------------------------------------------------
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  ------------------C-----------------------------------------
IRAK-0_af-2_Smoe  ------------------------------------------------------------
IRAK-0_af-1_Smoe  ------------------------------------------------------------
IRAK-0_e-2_Smoe   ------------------------------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ------------------------------------------------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   ------------------------------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ------------------------------------------------------------
IRAK-0_au-1_Smoe  ------------------------------------------------------------
IRAK-0_au-2_Smoe  ------------------------------------------------------------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ------------------------------------------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ------------------G-----------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------G-----------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------G-----------------------------------------
IRAK-0_t-1_Smoe   ------------------------------------------------------------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------------------C-----------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------G-----------------------------------------
IRAK-0_ac_Smoe    ------------------------------------------------------------
IRAK-0_z-2_Smoe   ------------------------------------------------------------
IRAK-0_k_Smoe     ------------------------------------------------------------
IRAK-0_y-1_Smoe   LYLHSTNLKFRYRHYRPLCMGKYHKGGLNFISCTFAMEFHAHPPHPIGQFNGQKPPRSSP
IRAK-0_z-1_Smoe   ------------------------------------------------------------
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    ------------------------------------------------------------
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    ------------------------------------------------------------
IRAK-0_g-2_Smoe   ------------------------------------------------------------
IRAK-0_a-2_Smoe   ------------------------------------------------------------
IRAK-0_d-2_Smoe   ------------------------------------------------------------
IRAK-0_y-2_Smoe   ----------------------------------------------------KKPPRSSP
IRAK-0_m-1_Smoe   ------------------------------------------------------------
IRAK-0_f_Smoe     ------------------------------------------------------------
IRAK-0_ar-2_Smoe  ------------------------------------------------------------
IRAK-0_e-1_Smoe   ------------------------------------------------------------
IRAK-0_d-1_Smoe   ------------------------------------------------------------
IRAK-0_m-2_Smoe   ------------------------------------------------------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------------------------------------------------VGLLL-F-VAD-
IRAK-0_bs_Smoe    ------------------------------------------------WMIPL-F-LLDR
IRAK-0_t-2_Smoe   ------------------------------------------------SIFIL-R-FAQ-
IRAK-0_as_Smoe    ------------------------------------------------WFLIA-T-HVDQ
IRAK-0_aq-2_Smoe  ---------------IGVGA---------------------------IILLILLA-LI-I
IRAK-0_af-2_Smoe  ------------------------------------------------VALQWMF-LDS-
IRAK-0_af-1_Smoe  ------------------------------------------------VALQWMF-LDS-
IRAK-0_e-2_Smoe   ------------------------------------------------LLLIL-C-FGTR
IRAK-0_bn_Smoe    ------------------------------------------------AI---MD-LDAG
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    --------------------------------------------------QRS-------
IRAK-0_ar-1_Smoe  ------------------------------------------------WLILA-C-VAGC
IRAK-0_bh_Smoe    ------------------------------------------------FLPF-PE-ISSG
IRAK-0_x_Smoe     ----------------------------------------------------V---YPH-
IRAK-0_n-1_Smoe   ------------------------------------------------LLLVA---VAAA
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ------------------------------------------------LT--LS--IAS-
IRAK-0_au-1_Smoe  ------------------------------------------------TILPIWF-LRI-
IRAK-0_au-2_Smoe  ------------------------------------------------TILPIWF-LRI-
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ------------------------------------------------LLLVA---VAAA
IRAK-0_a-1_Smoe   -----------------------------------------------YDYLPLKF-MQ--
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ---------------IGVGV---------------------------FIVFILFL-LS-V
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ---------------IAVGA---------------------------FIILILFF-LS-M
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------MFLRI-I-----
IRAK-0_bg_Smoe    ---------------IAVGA---------------------------FIGFILL--LS-L
IRAK-0_t-1_Smoe   ------------------------------------------------SIFIL-R-SAQ-
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ---------------IGVGA---------------------------IILLILLA-LI-I
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ---------------IAVGA---------------------------FIVLILFF-LS-M
IRAK-0_ac_Smoe    ------------------------------------------------TNLVS-IGFGSN
IRAK-0_z-2_Smoe   ------------------------------------------------ILLVL-L-LPEQ
IRAK-0_k_Smoe     -------------------------------------------------GFLL---VAS-
IRAK-0_y-1_Smoe   HPQAMVCAKKRYFTVMAATHI--------------------------LLHLILSL-VA--
IRAK-0_z-1_Smoe   ------------------------------------------------ILLVL-L-LPEQ
IRAK-0_bq_Smoe    ------------------------------------------------LVASVF--IAAF
IRAK-0_aj_Smoe    ------------------------------------------------FVLAIAM-IAIA
IRAK-0_br_Smoe    ------------------------------------------------LFCVF-I-LVPR
IRAK-0_l_Smoe     ------------------------------------------------AEIII-D-TGQ-
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------------------------------------------------FGLLL-F-VAD-
IRAK-0_bk_Smoe    ------------------------------------------------VFLLV-F--LCR
IRAK-0_g-2_Smoe   ------------------------------------------------LT--LS--IAS-
IRAK-0_a-2_Smoe   -------------------SDKLEPTKSIHGTDAGILTGMFDAPIELLLVILLCF-CPS-
IRAK-0_d-2_Smoe   ------------------------------------------------WQPDAFF-LSSG
IRAK-0_y-2_Smoe   HPQAMVCAKKRYFTVMEATHI--------------------------LLHLILSL-VA--
IRAK-0_m-1_Smoe   ------------------------------------------------------------
IRAK-0_f_Smoe     ------------------------------------------------TNLVS-IGFGSN
IRAK-0_ar-2_Smoe  ------------------------------------------------WLILA-C-VAGR
IRAK-0_e-1_Smoe   ------------------------------------------------LLLIL-C-FGTR
IRAK-0_d-1_Smoe   ------------------------------------------------WQPDAFF-LSSG
IRAK-0_m-2_Smoe   --------------------R----------------------------PFYN---IRP-


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    --AS---RN-TQHIVLVT--DKESDV------------TYIVEGSREGSNEAAGLNVVIP
IRAK-0_bs_Smoe    -SAA---Q-------------------GI------PPD----------------------
IRAK-0_t-2_Smoe   --AE---QY---YRNFT---SKIND---------------------------SFLFPLDP
IRAK-0_as_Smoe    -AAA---Q-------------------P-------IP-----------------------
IRAK-0_aq-2_Smoe  WLTS---RS------------------SS------GSH----------------------
IRAK-0_af-2_Smoe  LLAA---ST-AE---ISA-IRDIASALGV------PATVWNTSTD--------------P
IRAK-0_af-1_Smoe  LLAA---ST-AE---ISA-IRDIASALGV------PATVWNTSTD--------------P
IRAK-0_e-2_Smoe   PLAA---QQ------------------QR------PVD----------------------
IRAK-0_bn_Smoe    -TS---------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ----FFA-----------------------------------------------------
IRAK-0_ar-1_Smoe  -SVA---R--------------------A------PPD----------------------
IRAK-0_bh_Smoe    -RK----YC---------------------------------------------------
IRAK-0_x_Smoe     -EA---------------------------------------------------------
IRAK-0_n-1_Smoe   ALLGFFSPARLL---VLG-------QSSC------PLD----------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   -------NA------------------AP------V------------------------
IRAK-0_au-1_Smoe  TDGA---SV-LE---TTS-LIAAASVLGI------APGTWNFSTD--------------P
IRAK-0_au-2_Smoe  TDGA---SV-LE---TTS-LIAAASVLGI------APGTWNFSTD--------------P
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ALLRFFSPARLL---VLG-------QSSC------PLD----------------------
IRAK-0_a-1_Smoe   ---G---AI---------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    WLAS---SR------------------RR------RK-----------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   WLVS---RK------------------KN-------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    WLSS---RR------------------SK------SR-----------------------
IRAK-0_t-1_Smoe   --AA---LY---YRNFT---TKID----------------------------GPLYPLDP
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  WLTS---RS------------------SS------GSH----------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   WLVS---RK------------------KN-------------------------------
IRAK-0_ac_Smoe    DFSG---T--------------------L-------PR----------------------
IRAK-0_z-2_Smoe   -FAA---Q-------------------G-------LPD----------------------
IRAK-0_k_Smoe     -TT---------------------------------------------------------
IRAK-0_y-1_Smoe   LLSH---G-------------------PV------TP-----------------------
IRAK-0_z-1_Smoe   -FAA---Q-------------------G-------LPD----------------------
IRAK-0_bq_Smoe    ALAS---NS------------------TT------D------------------------
IRAK-0_aj_Smoe    ALAR---GA------------------HA------Q------------------------
IRAK-0_br_Smoe    -SSS---Q--------------------P------PT-----------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    --AS---RN-IE----LT--DKESDV------------TYIVEGSREGSNEAAGLNVVIP
IRAK-0_bk_Smoe    GVFA---S--------------------V-------PS----------------------
IRAK-0_g-2_Smoe   -------NA------------------AP------V------------------------
IRAK-0_a-2_Smoe   --CK---CL-LD----IGFPGNPEIA------------VDSN----FNWTLNGDLHPFLC
IRAK-0_d-2_Smoe   -AS----NS------------------VIRQVSNSS------------------------
IRAK-0_y-2_Smoe   LLSH---G-------------------PV------TP-----------------------
IRAK-0_m-1_Smoe   --------------------------AGV------SPEGVNGC--------------IHN
IRAK-0_f_Smoe     DFSG---T--------------------L-------PR----------------------
IRAK-0_ar-2_Smoe  -SVA---R--------------------A------PPD----------------------
IRAK-0_e-1_Smoe   PLAA---QQ------------------QR------PVD----------------------
IRAK-0_d-1_Smoe   -AS----NS------------------VIQQVSNSS------------------------
IRAK-0_m-2_Smoe   -PASNKYSAVNPSPLQVNDREIGITAAGV------PPEGVNGC--------------IHN


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    S-KHGLQDKYCCLKDGLG------------------SCVQECDSKI--------------
IRAK-0_bs_Smoe    ------------------------------------------------------------
IRAK-0_t-2_Smoe   ---HGLNGRYAGLWSNYS-------------------DT-QISRYI---------SYEVW
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  ------------------------------------------------------------
IRAK-0_af-2_Smoe  C-SGRWRGISCCNAQRLNSTCCS--SIYNPFPPVSTPCPDSSSANSST-----IVGVSLD
IRAK-0_af-1_Smoe  C-SGRWRGISCCNAQRVNSTCCS--SIYSPFES--TLCPDSSSANSST-----IVGVSLD
IRAK-0_e-2_Smoe   ------------------------------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ------------------------------------------------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   ------------------------------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ------------------------------------------------------------
IRAK-0_au-1_Smoe  C-VGGWTGVGCCRNN-SDALCCAFPQIYPPTPPL-TPCERTADAQVSA-----LILRS--
IRAK-0_au-2_Smoe  C-VGGWTGVGCCRNT-SDALCCAFPQIYPPTPPL-TPCERTADAQVST-----LILRS--
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ------------------------------------------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ----GGRQ----------------------------------------------------
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   ---YGLSGRYAGLWSNYS-------------------DI-DISQDM---------SYQVW
IRAK-0_b-2_Smoe   ----------CK------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------------------------------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    ------------------------------------------------------------
IRAK-0_z-2_Smoe   ------------------------------------------------------------
IRAK-0_k_Smoe     ------------------------------------------------------------
IRAK-0_y-1_Smoe   ------------------------------------------------------------
IRAK-0_z-1_Smoe   ------------------------------------------------------------
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    ------------------------------------------------------------
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    S-KHGLQDKYCCLKDGLG------------------SCVQECDSKI--------------
IRAK-0_bk_Smoe    ------------------------------------------------------------
IRAK-0_g-2_Smoe   ------------------------------------------------------------
IRAK-0_a-2_Smoe   Q-N------------------------------------------L---------SKRAF
IRAK-0_d-2_Smoe   --------------------------VRNP------------------------------
IRAK-0_y-2_Smoe   ------------------------------------------------------------
IRAK-0_m-1_Smoe   SKLGHFQTLFCIRKDKAKT---------------------------SRTRRRTMILR---
IRAK-0_f_Smoe     ------------------------------------------------------------
IRAK-0_ar-2_Smoe  ------------------------------------------------------------
IRAK-0_e-1_Smoe   ------------------------------------------------------------
IRAK-0_d-1_Smoe   --------------------------VRNP------------------------------
IRAK-0_m-2_Smoe   SKLGHFQTLFCIRKDKVKT---------------------------SRTHRRTMIRR---


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    ------------------------------------------------------------
IRAK-0_t-2_Smoe   MLSYNADTPRSFFLALVAIRNP--------------------------------------
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  ------------------------------------------------------------
IRAK-0_af-2_Smoe  SNFIMRVLS---------GSLPDSVCNLTSLVTLDLN--NNNLQGPIPRCIGIRLTRLKR
IRAK-0_af-1_Smoe  SNSIMRVLS---------GSLPDSVCNLTSLVTLDLN--NNNLQGPIPRCIGIRLTRLKK
IRAK-0_e-2_Smoe   ------------------------------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ------------------------------------------------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   -----------------------------FSVTADEFAFARNDRDPGRQCLAVR------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ------------------------------------------------------------
IRAK-0_au-1_Smoe  DLFGNQLLN---------GTLPEALCNLTSLRILDLG--LQRLSGQIPGCIGSRLSGLQI
IRAK-0_au-2_Smoe  DLFGNQLLN---------GTLPEALCNLTSLRILDLG--LQRLSGQIPGCIGSRLSGLQI
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   -----------------------------FSVTADEFAFARNDRDPGRQCLAVR------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   MLSYNAETPKSFFLALIAIRNP--------------------------------------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------------------------------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    ------------------------------------------------------------
IRAK-0_z-2_Smoe   ------------------------------------------------------------
IRAK-0_k_Smoe     ------------------------------------------------------------
IRAK-0_y-1_Smoe   ------------------------------------------------------------
IRAK-0_z-1_Smoe   ------------------------------------------------------------
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    ------------------------------------------------------------
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    ------------------------------------------------------------
IRAK-0_g-2_Smoe   ------------------------------------------------------------
IRAK-0_a-2_Smoe   AAGFTSSKTGLFYLA---------------------------------------------
IRAK-0_d-2_Smoe   ------------------------------------------------------------
IRAK-0_y-2_Smoe   ------------------------------------------------------------
IRAK-0_m-1_Smoe   ----------------------RVFC----------------------------------
IRAK-0_f_Smoe     ------------------------------------------------------------
IRAK-0_ar-2_Smoe  ------------------------------------------------------------
IRAK-0_e-1_Smoe   ------------------------------------------------------------
IRAK-0_d-1_Smoe   ------------------------------------------------------------
IRAK-0_m-2_Smoe   ----------------------RVFC----------------------------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    ---------------ERRSD----------------------------------------
IRAK-0_t-2_Smoe   --------------TS-WEL----------------------------------------
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  ------------------N-----------------------------------------
IRAK-0_af-2_Smoe  LGMAGGAGNLGTIPEELGSL----------------------------------------
IRAK-0_af-1_Smoe  LGMAGGAGNLGTIPEELGSL----------------------------------------
IRAK-0_e-2_Smoe   ---------------VTDPG----------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ---------------DPNPG----------------------------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   --------------E---------------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ------------------PA----------------------------------------
IRAK-0_au-1_Smoe  LRI-GDNRFNGSIPEELGEL----------------------------------------
IRAK-0_au-2_Smoe  LRI-GDNRFNGSIPEELGEL----------------------------------------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   --------------E---------------------------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------K-----------------------------------------
IRAK-0_t-1_Smoe   --------------REFWDL----------------------------------------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------------------N-----------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    ---------------EIGNL----------------------------------------
IRAK-0_z-2_Smoe   ---------------EPGNG----------------------------------------
IRAK-0_k_Smoe     ------------------------------------------------------------
IRAK-0_y-1_Smoe   ------------------------------------------------------------
IRAK-0_z-1_Smoe   ---------------EPGNG----------------------------------------
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    ----------------FTSN----------------------------------------
IRAK-0_br_Smoe    -------------------D----------------------------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    ---------------G--------------------------------------------
IRAK-0_g-2_Smoe   ------------------PG----------------------------------------
IRAK-0_a-2_Smoe   ------------------------------------------------------------
IRAK-0_d-2_Smoe   -------------------YRQLRSFPGPDRKSCYSLPVNASQRYLIRATFLYGNYDGRN
IRAK-0_y-2_Smoe   ------------------------------------------------------------
IRAK-0_m-1_Smoe   ---------------------LLNAFPSKD--LYYHAPTRMSLH----------------
IRAK-0_f_Smoe     ---------------EIGNL----------------------------------------
IRAK-0_ar-2_Smoe  ---------------DPNPD----------------------------------------
IRAK-0_e-1_Smoe   ---------------VTDPG----------------------------------------
IRAK-0_d-1_Smoe   -------------------YRQLRSFPGPDRKSCYSLPVNASQRYLIRATFLYGNYDGRN
IRAK-0_m-2_Smoe   ---------------------LLNAFPSKD--LYYHASTRMSLH----------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------KYY---------CCLK-------TGLGGCKQL-CET--NVEYFCCLK-------
IRAK-0_bs_Smoe    ARPG-V----------------------------------------AAYNTRK-------
IRAK-0_t-2_Smoe   TRPV-IL--------------WKARQTRLVGE----------------------------
IRAK-0_as_Smoe    -----G----------------------------------------IYFNPGR-------
IRAK-0_aq-2_Smoe  ------------------------------------------------------------
IRAK-0_af-2_Smoe  SSLE-Q----------------------------------------LYLDNTNLTG----
IRAK-0_af-1_Smoe  SSLE-Q----------------------------------------LYLDNTNLTG----
IRAK-0_e-2_Smoe   QLAN-V----------------------------------------LYYNTAN-------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  TQPN-V----------------------------------------VYYNQIN-------
IRAK-0_bh_Smoe    -----I----------------------------------------ILYFAEV-------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   -ELN-L----------------------------------------VIAAQLNRTQRFLF
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   PIEY-S---------------------------------------CWSCGEEK-------
IRAK-0_au-1_Smoe  RSLQ-Q----------------------------------------LFLDTTNISG----
IRAK-0_au-2_Smoe  RSLQ-Q----------------------------------------LFLDTTNISG----
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   -ELN-L----------------------------------------VIAAQLNRTQRFLF
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   TRPV-IL--------------WKARQTRLVGE----------------------------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------------------------------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    QSLR-K----------------------------------------IYMDACNLGG----
IRAK-0_z-2_Smoe   RGPN-L----------------------------------------IYFNTAN-------
IRAK-0_k_Smoe     ------------------------------------------------------------
IRAK-0_y-1_Smoe   ------------------------------------------------------------
IRAK-0_z-1_Smoe   RGPN-V----------------------------------------IYFNTAN-------
IRAK-0_bq_Smoe    -IDI-A---------------------------------------RPSCSDAY-------
IRAK-0_aj_Smoe    STAN-A---------------------------------------TFSCSDAY-------
IRAK-0_br_Smoe    SLPN-V----------------------------------------IYYNTMS-------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------KYY---------CCLK-------NGLGGCLQL-CET--NVKYFCCLK-------
IRAK-0_bk_Smoe    ISPN-I----------------------------------------VYSNTRK-------
IRAK-0_g-2_Smoe   PIEY-S---------------------------------------CWSCGEEK-------
IRAK-0_a-2_Smoe   ------VYYVKAGGENHTSAVWKANNGRPVPLGASLKLQVDG--NLVLYNP---------
IRAK-0_d-2_Smoe   TAPEFT----------------------------------------IYLNVTR-------
IRAK-0_y-2_Smoe   ------------------------------------------------------------
IRAK-0_m-1_Smoe   ----T--------------------------------VLLLSIVEL----------NYL-
IRAK-0_f_Smoe     QSLR-K----------------------------------------IYMDACNLGG----
IRAK-0_ar-2_Smoe  TEPN-L----------------------------------------VYYSPTN-------
IRAK-0_e-1_Smoe   QLPN-V----------------------------------------LYYNTAN-------
IRAK-0_d-1_Smoe   TAPEFT----------------------------------------IYLNVTR-------
IRAK-0_m-2_Smoe   ----I-------------------------------TVLLLSIVEL----------NYL-


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    --------------------------------------------------------NPFG
IRAK-0_bs_Smoe    --------------------------------------------------------TTQG
IRAK-0_t-2_Smoe   ------------------------------------------------------------
IRAK-0_as_Smoe    --------------------------------------------------------TTAG
IRAK-0_aq-2_Smoe  ----------------------------------------------------------SY
IRAK-0_af-2_Smoe  ----------PIPSSFGGMTSLQQLDIRYNRLSGRIPL-ELGRLTNLVELGIQV--NSLE
IRAK-0_af-1_Smoe  ----------PIPSSFGGMTSLQQLDIRYNRLSGRIPL-ELGRLSNLVELGIQV--NSLE
IRAK-0_e-2_Smoe   --------------------------------------------------------TSEG
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  --------------------------------------------------------TSAN
IRAK-0_bh_Smoe    --------------------------------------------------------TSMN
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   PAATASSCIQDFQASLQR--------------QGVAPNITVR-------CSIDSQTLESG
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   --------------------------------------------------------FTNG
IRAK-0_au-1_Smoe  ----------PIPASLGRLSNLTNLNLRSNALEGDLPE-EIGQLSNLVELSLQV--NRLT
IRAK-0_au-2_Smoe  ----------PIPASLGRLGNLTNLNLRSNALEGDLPE-EIGQLSNLIELSLQV--NRLT
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   PAATASTCIQDFQASLQR--------------QGVAPDITVR-------CSIDSQTLESG
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ----------------------------------------------------------SS
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ----------------------------------------------------------TD
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ----------------------------------------------------------ID
IRAK-0_t-1_Smoe   ------------------------------------------------------------
IRAK-0_b-2_Smoe   -------------CRQGYKGN---------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ----------------------------------------------------------SY
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ----------------------------------------------------------TD
IRAK-0_ac_Smoe    ----------ELPEEFGNLTSLEILWMAGNNFNGTFPE-FIGRLVALQDLDLGD--ITSG
IRAK-0_z-2_Smoe   --------------------------------------------------------TTEG
IRAK-0_k_Smoe     --------------GFGYMNTISSMETR--------------------------------
IRAK-0_y-1_Smoe   ------------TQAFGVMGTLAPMWGQ-------------------------------F
IRAK-0_z-1_Smoe   --------------------------------------------------------TTEG
IRAK-0_bq_Smoe    --------------------------------------------------------KITS
IRAK-0_aj_Smoe    --------------------------------------------------------TFTS
IRAK-0_br_Smoe    --------------------------------------------------------FSPG
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    --------------------------------------------------------NPLG
IRAK-0_bk_Smoe    --------------------------------------------------------TTPG
IRAK-0_g-2_Smoe   --------------------------------------------------------FTNG
IRAK-0_a-2_Smoe   ------------------------------------------------------------
IRAK-0_d-2_Smoe   --------------------------------------------------------WAEV
IRAK-0_y-2_Smoe   ------------TQAFGVMGTLAPMWGQ-------------------------------F
IRAK-0_m-1_Smoe   ----------HLTASFGYMTTLGSLWTL--------------------------------
IRAK-0_f_Smoe     ----------ELPEEFGNLTSLETLWMAGNNFNGTFPE-FIGRLVALQDLDLGD--ITSG
IRAK-0_ar-2_Smoe  --------------------------------------------------------TSTN
IRAK-0_e-1_Smoe   --------------------------------------------------------TSEG
IRAK-0_d-1_Smoe   --------------------------------------------------------WAEV
IRAK-0_m-2_Smoe   ----------HLAASFGYMTTLGSLWTL--------------------------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------TCF---------------------------------------------------
IRAK-0_bs_Smoe    ------SQF---------------------------------------------------
IRAK-0_t-2_Smoe   ------------------------------------------------------------
IRAK-0_as_Smoe    ------SQL---------------------------------------------------
IRAK-0_aq-2_Smoe  ------EKF---------------------------------------------------
IRAK-0_af-2_Smoe  ------GGIE-AVASLTRLEILTAFNNHFSGNLSLSIFRNLSSLRVLNLKLNNFTGGIPE
IRAK-0_af-1_Smoe  ------GGIE-AVASLTRLETLRAFNNHFSGNLSLSIFRNLSSLRVLNLKLNNFTGGIPE
IRAK-0_e-2_Smoe   ------SPF---------------------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ------STY---------------------------------------------------
IRAK-0_bh_Smoe    ------SGD---------------------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   ------STR---------------------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ------SSY---------------------------------------------------
IRAK-0_au-1_Smoe  ------GSIPDSYGDLTNLQTFRLFNNELSGGVSSSVLQGMTSLTDLNLRHNRFSGPVPD
IRAK-0_au-2_Smoe  ------GSIPDSYGNLTNLQTFRLFNNELSGGVSSSVLQGMASLTDLSLRHNRFSGPVPD
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ------STR---------------------------------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ------SPY---------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------DKF---------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------DTF---------------------------------------------------
IRAK-0_t-1_Smoe   ------------------------------------------------------------
IRAK-0_b-2_Smoe   ---------------------------ATSG-----------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------EKF---------------------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------DKF---------------------------------------------------
IRAK-0_ac_Smoe    ------GAIP-------------------------SSLNMLSGINKLMLRNCELSGSIPD
IRAK-0_z-2_Smoe   ------SPF---------------------------------------------------
IRAK-0_k_Smoe     ----------------------GLPFHDPSGSFPICVLQA--------------------
IRAK-0_y-1_Smoe   DPTQDSST---------------------KGTYHMCVIEAGSLLPHCLGNMSRNSSVTLV
IRAK-0_z-1_Smoe   ------SPF---------------------------------------------------
IRAK-0_bq_Smoe    ------AQM---------------------------------------------------
IRAK-0_aj_Smoe    ------RQM---------------------------------------------------
IRAK-0_br_Smoe    ------SAF---------------------------------------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------TCF---------------------------------------------------
IRAK-0_bk_Smoe    ------SAF---------------------------------------------------
IRAK-0_g-2_Smoe   ------SSY---------------------------------------------------
IRAK-0_a-2_Smoe   ------------------------------------------------------------
IRAK-0_d-2_Smoe   ------RVE---------------------------------------------------
IRAK-0_y-2_Smoe   DPTQDSST---------------------KGTYHMCVIEAGSLLPHCLGNMSRNSSVTLV
IRAK-0_m-1_Smoe   ----------------------SYFTPKNTGSYLVCILQA--------------------
IRAK-0_f_Smoe     ------GAIP-------------------------SSLNMLREINKLMLRNCELSGSIPD
IRAK-0_ar-2_Smoe  ------STY---------------------------------------------------
IRAK-0_e-1_Smoe   ------SPF---------------------------------------------------
IRAK-0_d-1_Smoe   ------RVE---------------------------------------------------
IRAK-0_m-2_Smoe   ----------------------SYFTPKNTGSYLVCILQA--------------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    QLC-DSSKEHYCCKK--------------NVSGSCVG-----------------------
IRAK-0_bs_Smoe    QKN-VETVMQFLYEHNP-----------PNGFASCLGYG---------------------
IRAK-0_t-2_Smoe   ------------------------------------------------------------
IRAK-0_as_Smoe    QSN-IDFVVGFLAQNTP-----------PNGYATCLGYG---------------------
IRAK-0_aq-2_Smoe  S-----C---------------------------CSSSQ---------------------
IRAK-0_af-2_Smoe  LDERFVNLTHLDLSFNQ-----------LSRGI-PGSLV---------------------
IRAK-0_af-1_Smoe  LDERFVNLTHLDLSFNQ-----------FSGGI-PGSLV---------------------
IRAK-0_e-2_Smoe   QRN-LDTVFEFLQGFNP-----------SNGFATSLGYG---------------------
IRAK-0_bn_Smoe    -------------------LQYVSFLAF---YSSCIGL----------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  QRN-VVAVMEFLYKNNP-----------PDGYATSLGYG---------------------
IRAK-0_bh_Smoe    LRE-FDIILSGTSLNNTPVFQSVNVANQAGGAYIALELH---------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   CPN-FTSVGDF---------------------TSATS-----------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   STA-LDNLLATLITNAP-----------VTGFFQSS-VQ---------------------
IRAK-0_au-1_Smoe  FGL-DSRLSTVDLGFNE-----------FSGPL-PGSLG---------------------
IRAK-0_au-2_Smoe  FGL-DSRLSTVDLGFNE-----------FSGPL-PGSLG---------------------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   CPN-FTSVGDF---------------------TSATS-----------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    HRK-FPP---------P-----------PPPL-SSSSGG---------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    T-----------------------------------------------------------
IRAK-0_t-1_Smoe   ------------------------------------------------------------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  S-----C---------------------------CSSSQ---------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    LGN-LSTLAHLDLSFNN-----------LTGVI-PSSLW---------------------
IRAK-0_z-2_Smoe   QKN-VETVLNFFYEHNP-----------PNGFATCLGYG---------------------
IRAK-0_k_Smoe     ---------------------------------------QVLTPI---------------
IRAK-0_y-1_Smoe   D-----------------------------------------------------------
IRAK-0_z-1_Smoe   QKN-VETVLNFFYEHNP-----------PNGFATCLGYG---------------------
IRAK-0_bq_Smoe    GRN-LLTVLATLQDQGP-----------AAGGYKSTSFG---------------------
IRAK-0_aj_Smoe    GAN-IQTVLATLLDQGP-----------AAGGFKSMSSG---------------------
IRAK-0_br_Smoe    ERN-LDAALQSVISSSR-----------S---SPSAALG---------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    QLC-DSSKKHYCCKK--------------NPFGTCLG-----------------------
IRAK-0_bk_Smoe    KLN-LDVVLGFLFKTVP-----------RNDSA-SYGFG---------------------
IRAK-0_g-2_Smoe   STA-LDNLLATLITNAP-----------VTGFFQSS-VQ---------------------
IRAK-0_a-2_Smoe   ------------------------------------------------------------
IRAK-0_d-2_Smoe   DIN-REVFVEMLF-LSP-----------GSTLEACLVSGGTGVPFISTLELRQLIGSMYS
IRAK-0_y-2_Smoe   D-----------------------------------------------------------
IRAK-0_m-1_Smoe   ---------------------------------------GTMAPV---------------
IRAK-0_f_Smoe     LGN-LSTLTHLDLSFNN-----------LTGVI-PSSLW---------------------
IRAK-0_ar-2_Smoe  QRN-VVAVLEFLYKNNP-----------PDGYATSLGYG---------------------
IRAK-0_e-1_Smoe   QRN-LDTVFEFLQGFNP-----------SNGFATSLGYG---------------------
IRAK-0_d-1_Smoe   DIN-REVFVEMLF-LSP-----------GSTLEACLVSGGTGVPFISTLELRQLIGSMYS
IRAK-0_m-2_Smoe   ---------------------------------------ETMAPV---------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    ------------------------------------------------------------
IRAK-0_t-2_Smoe   ------------------------------------------------------------
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  ------------------------------------------------------------
IRAK-0_af-2_Smoe  ------------------------------------------------------------
IRAK-0_af-1_Smoe  ------------------------------------------------------------
IRAK-0_e-2_Smoe   ------------------------------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ------------------------------------------------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   ------------------------------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ------------------------------------------------------------
IRAK-0_au-1_Smoe  ------------------------------------------------------------
IRAK-0_au-2_Smoe  ------------------------------------------------------------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ------------------------------------------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   ------------------------------------------------------------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------------------------------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    ------------------------------------------------------------
IRAK-0_z-2_Smoe   ------------------------------------------------------------
IRAK-0_k_Smoe     ---------------CI---------------------DETHV-----------------
IRAK-0_y-1_Smoe   ------------------------------------------------------------
IRAK-0_z-1_Smoe   ------------------------------------------------------------
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    ------------------------------------------------------------
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    ------------------------------------------------------------
IRAK-0_g-2_Smoe   ------------------------------------------------------------
IRAK-0_a-2_Smoe   ------------------------------------------------------------
IRAK-0_d-2_Smoe   APYEGRAHLQHIVRINFGALTTDDVRYPDDIVDRRWQSDLTRPNNLAAEAPGTIRVNTTS
IRAK-0_y-2_Smoe   ------------------------------------------------------------
IRAK-0_m-1_Smoe   ---------------CF---------------------GSIR------------------
IRAK-0_f_Smoe     ------------------------------------------------------------
IRAK-0_ar-2_Smoe  ------------------------------------------------------------
IRAK-0_e-1_Smoe   ------------------------------------------------------------
IRAK-0_d-1_Smoe   APYEGRAHLQHIVRINFGALTTDDVRYPDDIVDRRWQSDLTRPNNLAAEAPGTIRVNTTS
IRAK-0_m-2_Smoe   ---------------CF---------------------GSIR------------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ----------------------------------MCPKTVNLMNLPCH--CCWIVHWETS
IRAK-0_bs_Smoe    ----------------------------------DFPD----------------------
IRAK-0_t-2_Smoe   ------------------------------------------------------------
IRAK-0_as_Smoe    ----------------------------------KTPD----------------------
IRAK-0_aq-2_Smoe  ----------------------------------SLPT----------------------
IRAK-0_af-2_Smoe  ----------------------------------RLPSL---------------------
IRAK-0_af-1_Smoe  ----------------------------------RLPSL---------------------
IRAK-0_e-2_Smoe   ----------------------------------AFPN----------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ----------------------------------GFPN----------------------
IRAK-0_bh_Smoe    ----------------------------------DYNR----------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   -----------------------------------SAS----------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ----------------------------------SAEL----------------------
IRAK-0_au-1_Smoe  ----------------------------------GLSSL---------------------
IRAK-0_au-2_Smoe  ----------------------------------GLSSL---------------------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   -----------------------------------SAS----------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ----------------------------------ATPA----------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   ------------------------------------------------------------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ----------------------------------SLPT----------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    ----------------------------------AFPSL---------------------
IRAK-0_z-2_Smoe   ----------------------------------YFPN----------------------
IRAK-0_k_Smoe     ------TQMPPPEKK---------------------------------------------
IRAK-0_y-1_Smoe   ---------PPKDTP---------------------------------------------
IRAK-0_z-1_Smoe   ----------------------------------DFPN----------------------
IRAK-0_bq_Smoe    ----------------------------------SMSD----------------------
IRAK-0_aj_Smoe    ----------------------------------NLGD----------------------
IRAK-0_br_Smoe    ----------------------------------ASPD----------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ----------------------------------MCPKTVACHAIAAGSSIGRQVALNKS
IRAK-0_bk_Smoe    ----------------------------------KYPD----------------------
IRAK-0_g-2_Smoe   ----------------------------------SAEL----------------------
IRAK-0_a-2_Smoe   ------------------------------------------------------------
IRAK-0_d-2_Smoe   TVGVDTAAERPPERVMQTAVVGSNGSLTYRYFIPEFPA----------------------
IRAK-0_y-2_Smoe   ---------PPKDTP---------------------------------------------
IRAK-0_m-1_Smoe   ------THEQPQDKQ---------------------------------------------
IRAK-0_f_Smoe     ----------------------------------AFPSL---------------------
IRAK-0_ar-2_Smoe  ----------------------------------GFPN----------------------
IRAK-0_e-1_Smoe   ----------------------------------AFPN----------------------
IRAK-0_d-1_Smoe   TVGVDTAAERPPERVMQTAVVGSNGSLTYRYLIPEFPA----------------------
IRAK-0_m-2_Smoe   ------THEQPQVKQ---------------------------------------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    SFEQVL-------------------ILVHVAQHQVAIAGKAEEAGRGAKAKANSKYLEWI
IRAK-0_bs_Smoe    ------------------------------------------------------------
IRAK-0_t-2_Smoe   -----------------------------------------------------------N
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  ------------------------------------------------------------
IRAK-0_af-2_Smoe  ------------------------------------------------------------
IRAK-0_af-1_Smoe  ------------------------------------------------------------
IRAK-0_e-2_Smoe   ------------------------------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ------------------------------------------------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   ------------------------------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ------------------------------------------------------------
IRAK-0_au-1_Smoe  ------------------------------------------------------------
IRAK-0_au-2_Smoe  ------------------------------------------------------------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ------------------------------------------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   -----------------------------------------------------------N
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------------------------------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    ------------------------------------------------------------
IRAK-0_z-2_Smoe   ------------------------------------------------------------
IRAK-0_k_Smoe     ------------------------------------------------------------
IRAK-0_y-1_Smoe   ------------------------------------------------------------
IRAK-0_z-1_Smoe   ------------------------------------------------------------
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    ------------------------------------------------------------
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    SFNSIHKIVRWFSLDNANRNPQPSQAQAGYLSTSLSTRSPSLEAGRGAEAKANSKYLEWI
IRAK-0_bk_Smoe    ------------------------------------------------------------
IRAK-0_g-2_Smoe   ------------------------------------------------------------
IRAK-0_a-2_Smoe   ------------------------------------------------------------
IRAK-0_d-2_Smoe   ------------------------------------------------------------
IRAK-0_y-2_Smoe   ------------------------------------------------------------
IRAK-0_m-1_Smoe   ------------------------------------------------------------
IRAK-0_f_Smoe     ------------------------------------------------------------
IRAK-0_ar-2_Smoe  ------------------------------------------------------------
IRAK-0_e-1_Smoe   ------------------------------------------------------------
IRAK-0_d-1_Smoe   ------------------------------------------------------------
IRAK-0_m-2_Smoe   ------------------------------------------------------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    RE--WSLEEDGASSDIGSFVWSTNTGGSGAQVLALESSGNLVIRSK---IGDFLWQSFD-
IRAK-0_bs_Smoe    ------------------------------------------------------------
IRAK-0_t-2_Smoe   ATLQFTTDEGLKVEEDGDVVWSTKTANRGVRWLCISNRATIMLLDE--SGSNVIWQSSD-
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  ------------------------------------------------------------
IRAK-0_af-2_Smoe  ------------------------------------------------------------
IRAK-0_af-1_Smoe  ------------------------------------------------------------
IRAK-0_e-2_Smoe   ------------------------------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ------------------------------------------------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   ------------------------------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ------------------------------------------------------------
IRAK-0_au-1_Smoe  ------------------------------------------------------------
IRAK-0_au-2_Smoe  ------------------------------------------------------------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ------------------------------------------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    --------------------------------------------------------R---
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   ATLQFTVDGELKLEESGDVVWSSKTANRGVRWLAISNRATVMLLDK--SRMNVIWESSD-
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------------------------------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    ------------------------------------------------------------
IRAK-0_z-2_Smoe   ------------------------------------------------------------
IRAK-0_k_Smoe     -------------------------------FFAISGGARFTCGLDYGSRFPLCWGKLQ-
IRAK-0_y-1_Smoe   -------------------------------FLALSAGAQFTCGLIYGSQVPLCWGDLDN
IRAK-0_z-1_Smoe   ------------------------------------------------------------
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    ------------------------------------------------------------
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     ----------------------------------------------------------D-
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    RE--WSLEEDGASSDIGSFVWLTNTGGSGAQVLALESSGNLVIRSK---IGAFLWQSFD-
IRAK-0_bk_Smoe    ------------------------------------------------------------
IRAK-0_g-2_Smoe   ------------------------------------------------------------
IRAK-0_a-2_Smoe   ---------------DGTESWSTKTSGLGVAGMRLNQTGNLVLYRE---DDQVVWQSFD-
IRAK-0_d-2_Smoe   ------------------------------------------------------------
IRAK-0_y-2_Smoe   -------------------------------FLALSAGAQFTCGLIYGSQVPLCWGDLDN
IRAK-0_m-1_Smoe   -------------------------------LVTISSGGKFVCGLEYGNHFPICWGSLE-
IRAK-0_f_Smoe     ------------------------------------------------------------
IRAK-0_ar-2_Smoe  ------------------------------------------------------------
IRAK-0_e-1_Smoe   ------------------------------------------------------------
IRAK-0_d-1_Smoe   ------------------------------------------------------------
IRAK-0_m-2_Smoe   -------------------------------LVTISSGGKFVCGLEYGNHFPICWGSLE-


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ----HPCDAVLP------GMKLVASISKENKEP-GYFSLEV-------------------
IRAK-0_bs_Smoe    ------------------------------------------------------------
IRAK-0_t-2_Smoe   ----EPSDTVLLQRALTPGQKLVSWNTSEDSSD-GLYSLVIEKNRLQLLYASQPYWSFGN
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  ------------------------------------------------------------
IRAK-0_af-2_Smoe  ------------THLFLGHNNLSGAIPSSP--PPALQV--------------------LD
IRAK-0_af-1_Smoe  ------------THLFLGHNNLSGAIPSSP--PPALQV--------------------LD
IRAK-0_e-2_Smoe   ------------------------------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ------------------------------------------------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   ------------------------------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ------------------------------------------------------------
IRAK-0_au-1_Smoe  ------------TSLFIGHNRLNGSIPDNFGSFPALAQ--------------------LD
IRAK-0_au-2_Smoe  ------------TSLFIGHNRLNGSIPDNFGSFPALTQ--------------------LD
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ------------------------------------------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   ----EPSDTVLLQRAVKPGDKLVSWNTSEDSSD-GLYSLVMEKNRLKLLYASEPYWSFGN
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------------------------------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    ------------QNLLLGSNRLTGPLPSQLASR-SLQRLYC--VFLQLIYSSWLTFYCRD
IRAK-0_z-2_Smoe   ------------------------------------------------------------
IRAK-0_k_Smoe     ----VPAL-------------------------------------------------LQN
IRAK-0_y-1_Smoe   NKLAVPEK-------------------------------------------------LQK
IRAK-0_z-1_Smoe   ------------------------------------------------------------
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    ------------------------------------------------------------
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     ----GPGVGI------QGDRKLKDFNIREEANG-SLRAL------RRSFTVVNVSNGVRD
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ----HPCDAVLP------GMKLVASISRRTKSQ-GT------------------------
IRAK-0_bk_Smoe    ------------------------------------------------------------
IRAK-0_g-2_Smoe   ------------------------------------------------------------
IRAK-0_a-2_Smoe   ----HPTDTLVPHQLIKTGMKLVSSSP-GGTGE-GYFSFEVQ------------------
IRAK-0_d-2_Smoe   ------------------------------------------------------------
IRAK-0_y-2_Smoe   NKLAVPEK-------------------------------------------------LQK
IRAK-0_m-1_Smoe   ----APQS-------------------------------------------------FLN
IRAK-0_f_Smoe     ------------QNLLLGSNRLTGPLPSQLAST-SLQR--------------------LD
IRAK-0_ar-2_Smoe  ------------------------------------------------------------
IRAK-0_e-1_Smoe   ------------------------------------------------------------
IRAK-0_d-1_Smoe   ------------------------------------------------------------
IRAK-0_m-2_Smoe   ----APQS-------------------------------------------------FLN


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    --------------------------------T---------------------------
IRAK-0_t-2_Smoe   --------------------------------I---------------------------
IRAK-0_as_Smoe    --------------------------------T---------------------------
IRAK-0_aq-2_Smoe  --------------------------------T---------------------------
IRAK-0_af-2_Smoe  VSHNSLSGSLPNLP---QQLQVD--FSFNSL-----------------------------
IRAK-0_af-1_Smoe  VSHNSLSGSLPNLP---QQLQVD--FSFNSL-----------------------------
IRAK-0_e-2_Smoe   --------------------------------I---------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  --------------------------------A---------------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   --------------------------------I---------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   --------------------------------T---------------------------
IRAK-0_au-1_Smoe  ISHNMLAGSLQSLGGNTQLTQLD--VSFNFF-----------------------------
IRAK-0_au-2_Smoe  ISHNMLTGSLQSLGGNTQLTQLD--VSFNFF-----------------------------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   --------------------------------I---------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    --------------------------------A---------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   --------------------------------I---------------------------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  --------------------------------T---------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    VSFNELSGPMPSWISRIAQAKL---FAFRSL-----------------------------
IRAK-0_z-2_Smoe   --------------------------------T---------------------------
IRAK-0_k_Smoe     VSYTSLSSGANHCC------------------------------AIRSNDS-R-------
IRAK-0_y-1_Smoe   VSYSTIASGAYHVC------------------------------ALRSGAAAA-------
IRAK-0_z-1_Smoe   --------------------------------T---------------------------
IRAK-0_bq_Smoe    --------------------------------T---------------------------
IRAK-0_aj_Smoe    --------------------------------T---------------------------
IRAK-0_br_Smoe    --------------------------------V---------------------------
IRAK-0_l_Smoe     --------------------------------I---------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    --------------------------------T---------------------------
IRAK-0_g-2_Smoe   --------------------------------T---------------------------
IRAK-0_a-2_Smoe   ------------------------------------------------------------
IRAK-0_d-2_Smoe   --------------------------------FAFGRTYFAEIQELRASDV-RAFTFILP
IRAK-0_y-2_Smoe   VSYSTIASGAYHVC------------------------------ALRSGAAAA-------
IRAK-0_m-1_Smoe   VSYTAISSGASHAC------------------------------AIRSYDN-R-------
IRAK-0_f_Smoe     VSFNELSGPMPSWISRIAQAYVTNIFTFIFLIR---------------------------
IRAK-0_ar-2_Smoe  --------------------------------A---------------------------
IRAK-0_e-1_Smoe   --------------------------------I---------------------------
IRAK-0_d-1_Smoe   --------------------------------FAFGRTYFAEIQELRARDV-RAFTFILP
IRAK-0_m-2_Smoe   VSYTAISSGASHAC------------------------------AIRSYDN-R-------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ---------------------------WSSDEEEEEISFLFLVNSSLEIH----------
IRAK-0_bs_Smoe    ----------AYG-----------------------------------------------
IRAK-0_t-2_Smoe   ----------TSE---------------------EDM---------FAVFCWQNDGIVSL
IRAK-0_as_Smoe    ----------VYA-----------------------------------------------
IRAK-0_aq-2_Smoe  ----------IQQ-----------------------------------------------
IRAK-0_af-2_Smoe  ------------------------------------------------------------
IRAK-0_af-1_Smoe  ------------------------------------------------------------
IRAK-0_e-2_Smoe   ----------AYA-----------------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ----------VYA-----------------------------------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   ----------VNI-----------------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ----------LYG-----------------------------------------------
IRAK-0_au-1_Smoe  ------------------------------------------------------------
IRAK-0_au-2_Smoe  ------------------------------------------------------------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ----------ANI-----------------------------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   ----------TSD---------------------EDM---------FAVFCWQNDGIVSL
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ----------IQQ-----------------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    ------------------------------------------------------------
IRAK-0_z-2_Smoe   ----------VYG-----------------------------------------------
IRAK-0_k_Smoe     VDCWGEELAI-------ALLEDE----------SLVSVSSGVD--------------FSC
IRAK-0_y-1_Smoe   --------------VDCWGGKSNGESQPPVNGGPYVSLTSGWD--------------FSC
IRAK-0_z-1_Smoe   ----------VYG-----------------------------------------------
IRAK-0_bq_Smoe    ----------VYG-----------------------------------------------
IRAK-0_aj_Smoe    ----------VYG-----------------------------------------------
IRAK-0_br_Smoe    ----------AYA-----------------------------------------------
IRAK-0_l_Smoe     -----------------------------------------------HLLGWGKEH----
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------------------------------------------SHSSLEIH----------
IRAK-0_bk_Smoe    ----------VFG-----------------------------------------------
IRAK-0_g-2_Smoe   ----------LYG-----------------------------------------------
IRAK-0_a-2_Smoe   ----------PYALVLSAQSPLQRYGVWKFD---QEIGFVGVNFSSFNVY----------
IRAK-0_d-2_Smoe   S--------DTFF-----------------------------------------------
IRAK-0_y-2_Smoe   --------------VDCWGRKSNGESQPPVNGGPYVSLTSGWD--------------FSC
IRAK-0_m-1_Smoe   ADCWGSI-NS-------STVPNQ----------DFVSISSGSG--------------FSC
IRAK-0_f_Smoe     ----------IFS-----------------------------------------------
IRAK-0_ar-2_Smoe  ----------VYA-----------------------------------------------
IRAK-0_e-1_Smoe   ----------AYA-----------------------------------------------
IRAK-0_d-1_Smoe   N--------DTFF-----------------------------------------------
IRAK-0_m-2_Smoe   ADCWGSI-NS-------STVPNQ----------AFVSISSGSG--------------FSC


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    -------------GTKGVMW--------------STPTIGGVTDQSGHQFLKIYSNGEPR
IRAK-0_bs_Smoe    ------------------------------------------------------------
IRAK-0_t-2_Smoe   DLRGNFSQIETERDDLGLVFSWSCSSRGLRDQVMELPIN--GSQLTASTFIKLKPDGDVV
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  ------------------------------------------------------------
IRAK-0_af-2_Smoe  ------------------------------------------------------------
IRAK-0_af-1_Smoe  ------------------------------------------------------------
IRAK-0_e-2_Smoe   ------------------------------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ------------------------------------------------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   ------------------------------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ------------------------------------------------------------
IRAK-0_au-1_Smoe  ------------------------------------------------------------
IRAK-0_au-2_Smoe  ------------------------------------------------------------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ------------------------------------------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   DLRANFSQIETKRDDLGLVFSWSCSSRDLRDQVMELPID--GSQLTASTFIKLKPDGDVV
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------------------------------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    ------------------------------------------------------------
IRAK-0_z-2_Smoe   ------------------------------------------------------------
IRAK-0_k_Smoe     GVTQDGEV----------------------------------------------------
IRAK-0_y-1_Smoe   ALTALGRA----------------------------------------------------
IRAK-0_z-1_Smoe   ------------------------------------------------------------
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    ------------------------------------------------------------
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     -----------------------------------------------VAL----------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    -------------GTKGVMW--------------STPTIGGVTDQTGHQFLKIYSNGEPR
IRAK-0_bk_Smoe    ------------------------------------------------------------
IRAK-0_g-2_Smoe   ------------------------------------------------------------
IRAK-0_a-2_Smoe   -------------NRKMTVI--------------QSVALS---IVYSVRRIQLFSTGEVV
IRAK-0_d-2_Smoe   ------------------------------------------------------------
IRAK-0_y-2_Smoe   ALTALGRA----------------------------------------------------
IRAK-0_m-1_Smoe   GLTLDGAT----------------------------------------------------
IRAK-0_f_Smoe     ------------------------------------------------------------
IRAK-0_ar-2_Smoe  ------------------------------------------------------------
IRAK-0_e-1_Smoe   ------------------------------------------------------------
IRAK-0_d-1_Smoe   ------------------------------------------------------------
IRAK-0_m-2_Smoe   GLTLDGAT----------------------------------------------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    FTSRSFSTGNSTKSINLNPLFFGKSSLTRTCGIS--------------------------
IRAK-0_bs_Smoe    -----------------------------HTGCY-N-M----------------------
IRAK-0_t-2_Smoe   LYSWNWTGTNWIDFFRFSTLF--KCFLPSGCGRY-R-T--------------------CN
IRAK-0_as_Smoe    -----------------------------NTGCY-N-R----------------------
IRAK-0_aq-2_Smoe  -----------------------------QR----K-S----------------------
IRAK-0_af-2_Smoe  -----------------------------------NSVSSSAG-G------NGQGYFNCI
IRAK-0_af-1_Smoe  -----------------------------------NSVSSSAG-G------NGQGYFNCI
IRAK-0_e-2_Smoe   -----------------------------HTACY-N-M----------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  -----------------------------HSGCY-N-M----------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   -----------------------------QTNCRGN-I----------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   -----------------------------LLQCR-Q-D----------------------
IRAK-0_au-1_Smoe  -----------------------------------N-ISSAPTPVPQQPNLGSNAYFNCV
IRAK-0_au-2_Smoe  -----------------------------------N-ISSAPASVPPQPNLGSNAYFNCV
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   -----------------------------QTNCRGN-I----------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    -----------------------------PP----S-L----------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   -----------------------------------R-L----------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    -----------------------------------T-L----------------------
IRAK-0_t-1_Smoe   LYSWNWTGTNWIDFFRFSTLF--KCFLPSGCGRY-R-T--------------------CN
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  -----------------------------QR----K-S----------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   -----------------------------------R-L----------------------
IRAK-0_ac_Smoe    ------------------------------------------------------------
IRAK-0_z-2_Smoe   -----------------------------HTGCY-N-M----------------------
IRAK-0_k_Smoe     -------------------------------LCWG----YVPDQVPQPKN----------
IRAK-0_y-1_Smoe   -------------------------------VCWGALTNRTFTHNHAEPN----------
IRAK-0_z-1_Smoe   -----------------------------HTGCY-N-M----------------------
IRAK-0_bq_Smoe    -----------------------------FIQCR-G-D----------------------
IRAK-0_aj_Smoe    -----------------------------LIQCR-G-D----------------------
IRAK-0_br_Smoe    -----------------------------RGECY-N-N----------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    FTSRSFSTGNSTKSINLNPLFFGKSSLTRTCGIS--------------------------
IRAK-0_bk_Smoe    -----------------------------YCECY-N-M----------------------
IRAK-0_g-2_Smoe   -----------------------------LLQCR-Q-D----------------------
IRAK-0_a-2_Smoe   A-DIDWDILDLTKFFNGWIGW--DLSYPGVCGRY-S-M--------------------T-
IRAK-0_d-2_Smoe   -----------------------------RNQVVN--L----------------------
IRAK-0_y-2_Smoe   -------------------------------VCWGALTNRTFTHNHAEPN----------
IRAK-0_m-1_Smoe   -------------------------------ACWG----EVPGAIPKPAND---------
IRAK-0_f_Smoe     -----------------------------ASNCL-Q------------------------
IRAK-0_ar-2_Smoe  -----------------------------HSGCY-N-M----------------------
IRAK-0_e-1_Smoe   -----------------------------HTACY-N-M----------------------
IRAK-0_d-1_Smoe   -----------------------------RNQVVN--L----------------------
IRAK-0_m-2_Smoe   -------------------------------ACWG----EVPGAIPKPAND---------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    --SDQTNCAS-CIQQTYNEF----------------------------------------
IRAK-0_t-2_Smoe   S--ASGACEETCP-----------------------------------------------
IRAK-0_as_Smoe    --PDQQSCTV-CINIAYSRA----------------------------------------
IRAK-0_aq-2_Smoe  --SGIPIVTK-EIQEVVIVP----------------------------------------
IRAK-0_af-2_Smoe  AP--GLSCNR-SLPG----RSTSFAVRVGS---SQNLTNRDGTL----FR----------
IRAK-0_af-1_Smoe  AP--GLSCNR-SLPG----RSTSFAVRVGS---SEDLTNRDGTL----FR----------
IRAK-0_e-2_Smoe   --SDQPSCSS-CIQQAYANA----------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  --SDQPSCGQ-CIQNAYTNI----------------------------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   --GDGPSCSA-CTAAVVSSV----------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   --MSRDSCDQ-CARDIGQAV----------------------------------------
IRAK-0_au-1_Smoe  PSGSSGTCSS-SPPG----ERLFFAVNAGG---N-GLSSTTGSTVQVAFD----------
IRAK-0_au-2_Smoe  PSGSSGTCSS-SPPG----GRLFFAVNAGG---N-GLSSTTGSTVQVAFD----------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   --GDGPSCSA-CTAAVVSSV----------------------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    --HRIPAVSK-EIKEVVPIA----------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   --HNIPSESK-EIQEVKI------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    --HNIPNVSK-EIQEVRIDK----------------------------------------
IRAK-0_t-1_Smoe   S--ASGACEETCP-----------------------------------------------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  --SGIPIVTK-EIQEVVIVP----------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   --HNIPSESK-EIQEVKVDH----------------------------------------
IRAK-0_ac_Smoe    -----------I----KMDIGYQFAINCGG---P-QITSSSGTM----FS----------
IRAK-0_z-2_Smoe   --SDQPSCSE-CIKKAYQGI----------------------------------------
IRAK-0_k_Smoe     --------------------EIFTSVFVGGYTIC-GVTSSTGETLCWGQD----------
IRAK-0_y-1_Smoe   --------------------TSFDAIFAGRSYVC-GVERQTGNATCWGDNSYSQSNVPPY
IRAK-0_z-1_Smoe   --SDQPSCSE-CIKKAYQGI----------------------------------------
IRAK-0_bq_Smoe    --ISAQECSS-CARSAVQIL----------------------------------------
IRAK-0_aj_Smoe    --ITAQECSS-CARSAFQLL----------------------------------------
IRAK-0_br_Smoe    --LSPQDCVL-CLGMANQTI----------------------------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    --S-QGDCGQ-CFNIARDGI----------------------------------------
IRAK-0_g-2_Smoe   --MSRDSCDQ-CARDIGQAV----------------------------------------
IRAK-0_a-2_Smoe   ---REGECHCIGL-----------------------------------------------
IRAK-0_d-2_Smoe   --RNDIGAFQ-AYEPGYDNI----------------------------------------
IRAK-0_y-2_Smoe   --------------------TSFDAIFAGRSYVC-GVERQTGNATCWGDNSYSQSNVPPY
IRAK-0_m-1_Smoe   --------------------KKFMALFAGAYVVC-GITAQAGETLCWGGE----------
IRAK-0_f_Smoe     --S-RANCSR-V----RDGRSYQFAINCGG---P-QITSSSGTM----FS----------
IRAK-0_ar-2_Smoe  --SDQPSCGQ-CIQNAYTNI----------------------------------------
IRAK-0_e-1_Smoe   --SDQPSCSS-CIQQTYANV----------------------------------------
IRAK-0_d-1_Smoe   --RNDIGAFQ-AYEPGYDNI----------------------------------------
IRAK-0_m-2_Smoe   --------------------KKFMALFAGAYVVC-GITAQAGETLCWGGE----------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    ---RQVA--P----------LAVG-G-----V----------------------------
IRAK-0_t-2_Smoe   ------------------------------------------------------------
IRAK-0_as_Smoe    ---QTSA--P----------LTIG-A-----T----------------------------
IRAK-0_aq-2_Smoe  ---HYA------------------------------------------------------
IRAK-0_af-2_Smoe  ---SDGFAR-----------NSTGLHYLEADR----------------------------
IRAK-0_af-1_Smoe  ---SDGFAR-----------NSTGLHYLEADR----------------------------
IRAK-0_e-2_Smoe   ---RAR--------------FPIG-A-----R----------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ---QSVN--L----------YAVG-G-----A----------------------------
IRAK-0_bh_Smoe    ---TFYG--PVRVKLIPTQRSTLL-P-----FLSALEVYTVLDGLSAGTFASDAAALSNV
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   ---SFR---------------SNG-------S----------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ---KSRC--S----------SSLG-A-----K----------------------------
IRAK-0_au-1_Smoe  ---SDANPNN----------QSVGFFYGSGPG----------------------------
IRAK-0_au-2_Smoe  ---SDANP-------------NMGFFYGSGPG----------------------------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ---SFR---------------SNG-------S----------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ---SHH------------------------------------------------------
IRAK-0_t-1_Smoe   ------------------------------------------------------------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ---PYA------------------------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ---HKRA--T-----------NGG-G-----G----------------------------
IRAK-0_ac_Smoe    ---EDTA--M----------FTMG-TFTSNDQ----------------------------
IRAK-0_z-2_Smoe   ---QQNA--P----------YTLG-G-----T----------------------------
IRAK-0_k_Smoe     ------------------------------------------------------------
IRAK-0_y-1_Smoe   TRFK--------------------------------------------------------
IRAK-0_z-1_Smoe   ---QQNA--P----------YTLG-G-----T----------------------------
IRAK-0_bq_Smoe    ---NSTCVRN----------STKG-G-----R----------------------------
IRAK-0_aj_Smoe    ---NSTCVRN----------STKG-G-----R----------------------------
IRAK-0_br_Smoe    ---RGQA--P----------RTIG-A-----R----------------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    ---DEAA--P----------LTVG-A-----Q----------------------------
IRAK-0_g-2_Smoe   ---KSRC--S----------SSLG-A-----K----------------------------
IRAK-0_a-2_Smoe   ------------------------------------------------------------
IRAK-0_d-2_Smoe   ---SLPG--IINFAFQRTAEANLG-P-----ILNAMEVLRIVNRQS-PTNLDDVNSLGQF
IRAK-0_y-2_Smoe   TRFK--------------------------------------------------------
IRAK-0_m-1_Smoe   ------------------------------------------------------------
IRAK-0_f_Smoe     ---EDTA--M----------FTMG-TFTSNDQ----------------------------
IRAK-0_ar-2_Smoe  ---QSVN--L----------YAVG-G-----A----------------------------
IRAK-0_e-1_Smoe   ---RTR--------------FPIG-A-----R----------------------------
IRAK-0_d-1_Smoe   ---SLPG--IINFAFQRTAEANLG-P-----ILNAMEFFIFYAFIS-YDPFFAVNSLGQF
IRAK-0_m-2_Smoe   ------------------------------------------------------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    ------------------LWT-----N-D---------------------TS--NRCRL-
IRAK-0_t-2_Smoe   ------------------------------------------------------------
IRAK-0_as_Smoe    ------------------VWL-----N-E---------------------TVHQYACSL-
IRAK-0_aq-2_Smoe  ----------------------------------------------------------L-
IRAK-0_af-2_Smoe  ------------------NWA-----LELS--------------------S----EFSS-
IRAK-0_af-1_Smoe  ------------------NWA-----LELS--------------------S----EFSS-
IRAK-0_e-2_Smoe   ------------------FWR-----N-S---------------------TA--ERCNM-
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ------------------IWI-----N-Q---------------------TF--QRCRM-
IRAK-0_bh_Smoe    KETFNLEGAGDPCLPSRYKWDWINCDN---------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   -------------------------------------------------------TC-L-
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ------------------IQ---------------------------------LYGCFL-
IRAK-0_au-1_Smoe  ------------------LWA-----LEVS--------------------G----SEGG-
IRAK-0_au-2_Smoe  ------------------LWA-----LEVS--------------------G----SEGG-
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   -------------------------------------------------------TC-L-
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   ------------------------------------------------------------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ----------------------------------------------------------L-
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------VA--------------------------------------LA
IRAK-0_ac_Smoe    ------------------AWV-----VGS---------------------TG--YSDGF-
IRAK-0_z-2_Smoe   ------------------YWI-----N-E---------------------TE--IRCRL-
IRAK-0_k_Smoe     -----------------------------S---SAFVVPAGYKFSRLAGGY--HHMCGI-
IRAK-0_y-1_Smoe   ---------------------------------------------TIAPSM--FHTCGL-
IRAK-0_z-1_Smoe   ------------------YWI-----N-E---------------------TE--IRCRL-
IRAK-0_bq_Smoe    ------------------IH---------------------------------PGNCFL-
IRAK-0_aj_Smoe    ------------------VY---------------------------------LDHCFL-
IRAK-0_br_Smoe    ------------------LFS-----N-S---------------------SD--YSCYL-
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    ------------------YWV-----N-S---------------------SS--YRCYL-
IRAK-0_g-2_Smoe   ------------------IQ---------------------------------LYGCFL-
IRAK-0_a-2_Smoe   ------------------------------------------------------------
IRAK-0_d-2_Smoe   IQQFGLSGTGDPCLP--VMWDWITCSN---------------------------------
IRAK-0_y-2_Smoe   ---------------------------------------------TIAPSM--FHTCGL-
IRAK-0_m-1_Smoe   -----------------------------KSNPSPAIPPPGLKFSYITGGF--RHTCGV-
IRAK-0_f_Smoe     ------------------AWV-----VGS---------------------TG--YSDGF-
IRAK-0_ar-2_Smoe  ------------------IWI-----N-Q---------------------TF--QRCRM-
IRAK-0_e-1_Smoe   ------------------FWR-----N-S---------------------TA--QRCNM-
IRAK-0_d-1_Smoe   IQQFGLSGTGDPCLP--VMWNWITCSN---------------------------------
IRAK-0_m-2_Smoe   -----------------------------KSNPSPAIPPPGLKFSYITGGF--RHTCGV-


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    -RFEN---------YN----F--------------TA---------ELV-----------
IRAK-0_t-2_Smoe   ------------------------------------------------------------
IRAK-0_as_Smoe    -TFEV---------YN----F--------------TD---------SLL-----------
IRAK-0_aq-2_Smoe  -HHSP---------YH----K--------------GA---------PLD-----------
IRAK-0_af-2_Smoe  -TVTV---------PA----T-------------I-S---------GVP-----------
IRAK-0_af-1_Smoe  -TVTF---------PA----T-------------I-S---------GVP-----------
IRAK-0_e-2_Smoe   -RFEN---------SN----F--------------TR---------DLP-----------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  -RYDP---------SS----F--------------E-----------IV-----------
IRAK-0_bh_Smoe    -----------------------------------GS---------P-------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   -DYAH------------------------------------------IY-----------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   -RYEN---------HP----F--------------FS---------VLD-----------
IRAK-0_au-1_Smoe  -TLPF---------QG----F-------------INM---------TGA-----------
IRAK-0_au-2_Smoe  -TLPF---------QG----F-------------INM---------TGA-----------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   -DYAH------------------------------------------IY-----------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ----LPSSGTA-------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    -----------------------------------------------------------Y
IRAK-0_t-1_Smoe   ------------------------------------------------------------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  -HHSP---------YH----K--------------GA---------PLD-----------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   RSVSPPEKGLEKIIVHVDCAR--------------GS---------PASVSHQSVSATQI
IRAK-0_ac_Smoe    -VRAF---------EN----T-------------TVP---------V-L-----------
IRAK-0_z-2_Smoe   -RYEN---------YN----L--------------TG-----------------------
IRAK-0_k_Smoe     -RSDN---------HQVVCWGLNKAQQLQVPRDAT----------------FSAIS----
IRAK-0_y-1_Smoe   -IRDT---------GVADCWGDDFYSQV--------NATSLGVTFST-------LA----
IRAK-0_z-1_Smoe   -RYEN---------YN----L--------------TG-----------------------
IRAK-0_bq_Smoe    -RYED---------HF----F--------------SS---------ILD-----------
IRAK-0_aj_Smoe    -RYED---------HF----F--------------SS---------TLD-----------
IRAK-0_br_Smoe    -RYEN---------YD----F--------------LG---------GV------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    -RFEN---------YN----F--------------IP---------G-------------
IRAK-0_g-2_Smoe   -RYEN---------HP----F--------------FS---------VLD-----------
IRAK-0_a-2_Smoe   ------------------------------------------------------------
IRAK-0_d-2_Smoe   -----------------------------------DG---------I-------------
IRAK-0_y-2_Smoe   -IRDT---------GVADCWGDDFYSQV--------NATSLGVTFST-------LA----
IRAK-0_m-1_Smoe   -RADN---------HQTVCWGDNRFAQLRVPENAT----------------FSAIS----
IRAK-0_f_Smoe     -VRAF---------EN----T-------------TVP---------V-L-----------
IRAK-0_ar-2_Smoe  -RYDP---------SS----F--------------E-----------IV-----------
IRAK-0_e-1_Smoe   -RFEN---------SN----F--------------TR---------DLP-----------
IRAK-0_d-1_Smoe   -----------------------------------DG---------I-------------
IRAK-0_m-2_Smoe   -RADN---------HQAVCWGDNRFAQLRVPENAT----------------FSAIS----


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    NMSVLGVLGPNVSA--PAPA----------------------------------------
IRAK-0_t-2_Smoe   --DTFARRGEDCQP----PYPLET---------CEDQLEYRFVRRE-GADYFS-------
IRAK-0_as_Smoe    ASHMLGILGPNASA--PAPL----------------------------------------
IRAK-0_aq-2_Smoe  ---KVARSIPGDD-----A-----------------------------------------
IRAK-0_af-2_Smoe  PEDDPSLYQTMRWS--SSYL-----------------------AYH-GGNLAPGTYSVSL
IRAK-0_af-1_Smoe  PEDNSSLYQTMRWS--SSYL-----------------------AYH-GGNLAPGTYSVSL
IRAK-0_e-2_Smoe   S-GTLGILGPNASA--PAPP----------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  P-GTLGIVGPNISS--PAPA----------------------------------------
IRAK-0_bh_Smoe    P-RINALTLSNMKL--QGAI----------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   AASI-----VNLD--GP-------------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   E-S---LLCLNCSS--IASS----------------------------------------
IRAK-0_au-1_Smoe  GNTEQELYRSMRWS--SSYI-----------------------AYH-GYSLRPGNYTVML
IRAK-0_au-2_Smoe  GNTEQELYRSMRWS--SSYI-----------------------AYH-GYSLRPGNYTVML
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   AASI-----VNLN--GP-------------------------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   E-KESSRGLPSNQA---SS-----------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    N-SPFSPFAPNAAA---AP-----------------------------------------
IRAK-0_t-1_Smoe   --DTFARRGEDCQP----PYPLET---------CEDQLEYRFVRRE-GADYFS-------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ---KVARSIPGDD-----A-----------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   E-KESSRGLPSNQA---SS-----------------------------------------
IRAK-0_ac_Smoe    GTVDRGLYQTSRSA--PSSL-----------------------RYI-GLGMVNGAYTLEF
IRAK-0_z-2_Smoe   -LTLFGIVGPNNSA--PAPA----------------------------------------
IRAK-0_k_Smoe     -A-------------------------------------------------------GDI
IRAK-0_y-1_Smoe   -A-------------------------------------------------------GDF
IRAK-0_z-1_Smoe   -LTLFGIVGPNNSA--PAPA----------------------------------------
IRAK-0_bq_Smoe    K-D---TNQGNCSTSIPASS----------------------------------------
IRAK-0_aj_Smoe    I-V---SSIANCS--TPSSS----------------------------------------
IRAK-0_br_Smoe    --------TPR-------------------------------------------------
IRAK-0_l_Smoe     --------HSDLS---------------------------------------G-------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    ----YEL--PGDLS--PAVT----------------------------------------
IRAK-0_g-2_Smoe   E-S---LLCLNCSS--IASS----------------------------------------
IRAK-0_a-2_Smoe   --KSDKGTQTYLEP----VDSLDGTLGCRLSHEGDLAMEYRLVAGDKFY---D-------
IRAK-0_d-2_Smoe   P-RVNGIILPNSNL--NGTI----------------------------------------
IRAK-0_y-2_Smoe   -A-------------------------------------------------------GDF
IRAK-0_m-1_Smoe   -A-------------------------------------------------------GDF
IRAK-0_f_Smoe     GTVDRGLYQTSRSA--PSSL-----------------------RYI-GLGMVNGAYTLEF
IRAK-0_ar-2_Smoe  P-GTLGIVGPNISS--PAPA----------------------------------------
IRAK-0_e-1_Smoe   S-GTLGILGPNASA--PAPP----------------------------------------
IRAK-0_d-1_Smoe   P-RVNGIILPNSNL--NGTI----------------------------------------
IRAK-0_m-2_Smoe   -A-------------------------------------------------------GDF


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    ------------------------------------------------------------
IRAK-0_t-2_Smoe   ------------------------------------------------------------
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  ------------------------------------------------------------
IRAK-0_af-2_Smoe  YFCETVFTNA------SYRAMDVVVQGEV-IARQ-LDV---VREVGP--R-TAYKITRNA
IRAK-0_af-1_Smoe  YFCETVFTNA------SYRAMDVVVQGEV-IARQ-LDV---VREVGP--R-TAYKITRNA
IRAK-0_e-2_Smoe   ------------------------------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ------------------------------------------------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     ------------------------------------SF---NVSPAP--C-VSA------
IRAK-0_n-1_Smoe   ------------------------------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ------------------------------------------------------------
IRAK-0_au-1_Smoe  YFAELVFTEP------GYRIFDVVLQGRV-VLEN-LDI---AREAGA--R-AAYVMSRNI
IRAK-0_au-2_Smoe  YFAELVFTEP------GYRIFDVVLQGRV-VLEN-LDI---AREAGA--R-AAYVMSRNI
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ------------------------------------------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   ------------------------------------------------------------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------------------------------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    HFAEIQLDNSTTWLGITRRLFDIYLQGTQ-RVKD-FNI---QNEAGGSSR-ALVRTFRNV
IRAK-0_z-2_Smoe   ------------------------------------------------------------
IRAK-0_k_Smoe     YTCGVTRD----------ANARLLCWGNNAVQYREIDL---HASQAV--C-TNE------
IRAK-0_y-1_Smoe   YTCGVNAE-----------DLAVRCWGNGV-QGT-KDFARVKVAPTV--CRAAR------
IRAK-0_z-1_Smoe   ------------------------------------------------------------
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    ------------------------------------------------------------
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    ------------------------------------------------------------
IRAK-0_g-2_Smoe   ------------------------------------------------------------
IRAK-0_a-2_Smoe   ------------------------------------------------------------
IRAK-0_d-2_Smoe   ------------------------------------------------------------
IRAK-0_y-2_Smoe   YTCGVNAE-----------DLAVRCWGNGV-QGT-KDFARVKVAPTV--CRTAR------
IRAK-0_m-1_Smoe   YTCGVRLD----------RAMKILCWGNSGVLKN-EDF---NASQGV--C-TSR------
IRAK-0_f_Smoe     HFAEIQLDNSTTWLGITRRLFDIYLQGTQ-RVKD-FNI---QNEAGGSSR-ALVRTFRNV
IRAK-0_ar-2_Smoe  ------------------------------------------------------------
IRAK-0_e-1_Smoe   ------------------------------------------------------------
IRAK-0_d-1_Smoe   ------------------------------------------------------------
IRAK-0_m-2_Smoe   YTCGVRLD----------RAMKIVCWGNSGVLKN-EDF---NASQGV--C-TSR------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    ---------------P--------------------------------------------
IRAK-0_t-2_Smoe   ---------------T--------------------------------------------
IRAK-0_as_Smoe    ---------------TS-------------------------------------------
IRAK-0_aq-2_Smoe  ------------------------------------------------------------
IRAK-0_af-2_Smoe  TVT-DGSLSIEFIFT---------------------------------------------
IRAK-0_af-1_Smoe  TVT-DGSLSIEFIFT---------------------------------------------
IRAK-0_e-2_Smoe   ---------------PV-------------------------------------------
IRAK-0_bn_Smoe    -----------------------------------LQIVPRSL-----------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ---------------PG-------------------------------------------
IRAK-0_bh_Smoe    ---------------PNGLSRLTGLNIIRLDGNHLTGGLPDLSALKNLTL------FTS-
IRAK-0_x_Smoe     ----------------------CGRDEYQFDQL---------------------------
IRAK-0_n-1_Smoe   ------------------------------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ---------------PG-------------------------------------------
IRAK-0_au-1_Smoe  TINNSGSVSVELVYR---------------------------------------------
IRAK-0_au-2_Smoe  TINNSGSVSVELVYR---------------------------------------------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ------------------------------------------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   ---------------T--------------------------------------------
IRAK-0_b-2_Smoe   ----------------------CRK-----------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------------------------------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    EVT-NNVLDMHFVWRVF-------------------------------------------
IRAK-0_z-2_Smoe   ---------------PI-------------------------------------------
IRAK-0_k_Smoe     ----------------------CGKNQYRVNRT---------------------------
IRAK-0_y-1_Smoe   ----------------------CSKHQYQLP-----------------------------
IRAK-0_z-1_Smoe   ---------------PI-------------------------------------------
IRAK-0_bq_Smoe    ---------------LA-------------------------------------------
IRAK-0_aj_Smoe    ---------------LA-------------------------------------------
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     ---------------P--------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    ---------------PV-------------------------------------------
IRAK-0_g-2_Smoe   ---------------PG-------------------------------------------
IRAK-0_a-2_Smoe   ---------------Y--------------------------------------------
IRAK-0_d-2_Smoe   ---------------PAGVSQMTGLNILDLRNNSLSGSIPDMSRLSVLRQLHLESNRLSG
IRAK-0_y-2_Smoe   ----------------------CSKHQYQLP-----------------------------
IRAK-0_m-1_Smoe   ----------------------CGKNQYELHG----------------------------
IRAK-0_f_Smoe     QVT-NNVLDMHFVWRVF-------------------------------------------
IRAK-0_ar-2_Smoe  ---------------P--------------------------------------------
IRAK-0_e-1_Smoe   ---------------PV-------------------------------------------
IRAK-0_d-1_Smoe   ---------------PAGVSQMTGLNILDLRNNSLSGSIPDMSRLSVLRQLHLESNRLSG
IRAK-0_m-2_Smoe   ----------------------CGKNQYELHG----------------------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    --------------------------------------------------IPPL------
IRAK-0_t-2_Smoe   -------------------------------------NYSTP------------------
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  ----------------------------------------PP--------KSTP------
IRAK-0_af-2_Smoe  ------------------------------------------------------------
IRAK-0_af-1_Smoe  ------------------------------------------------------------
IRAK-0_e-2_Smoe   ----------------------------------------VP--------PPT-------
IRAK-0_bn_Smoe    --------------------------P-------------PP--------PPEE------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ---------------------------PGLALGPDPDPDPAP--------APAP------
IRAK-0_bh_Smoe    --------------------------G-------------NP--------CLLE------
IRAK-0_x_Smoe     ---------------------------------------S--------------------
IRAK-0_n-1_Smoe   -------------------------------------TD--P--------GTV-------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ---------------------------Y-----------DDN--------LKSALA----
IRAK-0_au-1_Smoe  ------------------------------------------------------------
IRAK-0_au-2_Smoe  ------------------------------------------------------------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   -------------------------------------TD--P--------GTV-------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ----------------------------------------SP--------DQTQ------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ----------------------------------------PP--------PPSH------
IRAK-0_t-1_Smoe   -------------------------------------NYSTP------------------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ----------------------------------------PP--------KSTP------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ----------------------------------------SP--------DQTQ------
IRAK-0_ac_Smoe    ------------------------------------------------------------
IRAK-0_z-2_Smoe   ---------------------------P-----------SNP--------PPSQ------
IRAK-0_k_Smoe     ---------------------------------------S--------------------
IRAK-0_y-1_Smoe   ---------------------------------------SS-------------------
IRAK-0_z-1_Smoe   ---------------------------P-----------SNP--------PPSQ------
IRAK-0_bq_Smoe    --------------------------IF-----------QSN--------SRTALEFLKA
IRAK-0_aj_Smoe    --------------------------IF-----------QPN--------SKTALEFLEI
IRAK-0_br_Smoe    ----------------------------------------IP--------EGTI------
IRAK-0_l_Smoe     -------------------------------------LISTI------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    ------------------------------------------------------------
IRAK-0_g-2_Smoe   ---------------------------Y-----------DDN--------LKSALA----
IRAK-0_a-2_Smoe   -------------------------------------LPLKF------------------
IRAK-0_d-2_Smoe   DFPESLENIQTLQLLYLQNNLLTGSIP-------------EDLLNRRGLDFQYS------
IRAK-0_y-2_Smoe   ---------------------------------------SS-------------------
IRAK-0_m-1_Smoe   ---------------------------------------S--------------------
IRAK-0_f_Smoe     ------------------------------------------------------------
IRAK-0_ar-2_Smoe  --------------------------------------------------DPAP------
IRAK-0_e-1_Smoe   ----------------------------------------VP--------PPT-------
IRAK-0_d-1_Smoe   DFPESLQNIQTLQLLYIQNNLLTGSIP-------------EDLLNRRGLDFQYS------
IRAK-0_m-2_Smoe   ---------------------------------------S--------------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ----------------------------------------------------------FE
IRAK-0_bs_Smoe    ------------------------------------------------------------
IRAK-0_t-2_Smoe   ----------------------------VPEASV-EAC------QGRRESNCTCTAAF-Y
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  ------------------------------------------------------------
IRAK-0_af-2_Smoe  ------------------------------------------------------------
IRAK-0_af-1_Smoe  ------------------------------------------------------------
IRAK-0_e-2_Smoe   ------------------------------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ------------------------------------------------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     -------------------L-------PCPVLRD-KVCLACSQCLN-MQEISACGAS---
IRAK-0_n-1_Smoe   ------------------------------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   TLSRRGSSFTATV-GS-GKSQVFVLGECRGDLSS-QQC-------------DSCVRVA-M
IRAK-0_au-1_Smoe  ------------------------------------------------------------
IRAK-0_au-2_Smoe  ------------------------------------------------------------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ------------------------------------------------------------
IRAK-0_a-1_Smoe   -------------------------------LSQ-ADC------LETCLTNSSCKAVLF-
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   ----------------------------VPEASV-EAC------QGRCESNCTCTAAF-Y
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------------------------------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    ------------------------------------------------------------
IRAK-0_z-2_Smoe   ------------------------------------------------------------
IRAK-0_k_Smoe     -------------------SP-----QQCPSLSD-KVCLECSACVGGDFEISPCGAD---
IRAK-0_y-1_Smoe   ---------------------------FCPGMGNYKACVD--------------------
IRAK-0_z-1_Smoe   ------------------------------------------------------------
IRAK-0_bq_Smoe    KVPRNARKFVAAVAGIGSAVPAYALGQCIPDLSA-ADC-------------ASCLAAA-E
IRAK-0_aj_Smoe    RVPQSARKYVAAVAGIESAAPAYALGQCVPDLSA-ADC-------------VACLAAA-E
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     --------------------------QVLPEFE-----------TG--------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ----------------------------------------------------------FE
IRAK-0_bk_Smoe    ------------------------------------------------------------
IRAK-0_g-2_Smoe   TLSRRGSSFTATV-GS-GKSQVFVLGECRGDLSS-QQC-------------DSCVRVA-M
IRAK-0_a-2_Smoe   --------------------------MQGAILSQ-ADC------LETCLTNSSCKAVLF-
IRAK-0_d-2_Smoe   ------------------------------------------------------------
IRAK-0_y-2_Smoe   ---------------------------FCPGMGNYKACVD--------------------
IRAK-0_m-1_Smoe   --------------------------TSCPSLSD-KVCLDCSICVGDNVEISPCGDS---
IRAK-0_f_Smoe     ------------------------------------------------------------
IRAK-0_ar-2_Smoe  ------------------------------------------------------------
IRAK-0_e-1_Smoe   ------------------------------------------------------------
IRAK-0_d-1_Smoe   ------------------------------------------------------------
IRAK-0_m-2_Smoe   --------------------------TSCPSLSD-KVCLDCSICVGDNVEISPCGDS---


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    TAEGYLCIVHEVRFFRGQGGMQAP---GRTCEN-SQHH----------YML-EATAK---
IRAK-0_bs_Smoe    ------------------------------------------------------------
IRAK-0_t-2_Smoe   N--------------------------DGSCFLTHGDV----------Q-----------
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  ------------------------------------------------------------
IRAK-0_af-2_Smoe  --------------------------------------GPDRYINPNIFRLAP-QS----
IRAK-0_af-1_Smoe  --------------------------------------GPDRYINPNIFRLAP-QS----
IRAK-0_e-2_Smoe   ------------------------------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ------------------------------------------------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     --------------------------ADRMCG----------------------------
IRAK-0_n-1_Smoe   ------------------------------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   RNMTDRC----------------IGNTSGSILLNSCYTRFDAF-----------------
IRAK-0_au-1_Smoe  --------------------------------------GRDRYLDIGPWTL-R-NS----
IRAK-0_au-2_Smoe  --------------------------------------GRDRYLDIGPWTL-R-NS----
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ------------------------------------------------------------
IRAK-0_a-1_Smoe   ---------------------EDN---NRTCFH-LTEV----------YTL-NVTR----
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    -------------------------------------------------------F----
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   D--------------------------DGSCFLTHGDV----------Q-----------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------------------------------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    ------------------------------------------------------------
IRAK-0_z-2_Smoe   ------------------------------------------------------------
IRAK-0_k_Smoe     --------------------------SDRKCG----------------------------
IRAK-0_y-1_Smoe   ------------------------------------------------------------
IRAK-0_z-1_Smoe   ------------------------------------------------------------
IRAK-0_bq_Smoe    NAIASTC----------------RGGGGGVCYYSSCTLFFQRS-----------------
IRAK-0_aj_Smoe    NVIASTC----------------RGGGGGVCYYASCTLFFQGS-----------------
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    TAEGCLCIVHEVRFFREQGGMQAP---GRTCEN-SQHH----------YML-EATVRYFY
IRAK-0_bk_Smoe    ------------------------------------------------------------
IRAK-0_g-2_Smoe   RNMTDRC----------------IGNTSGSILLNSCYTRFDAF-----------------
IRAK-0_a-2_Smoe   ---------------------EDN---NRTCFH-LTEV----------YTL-NVTR----
IRAK-0_d-2_Smoe   ------------------------------------------------------------
IRAK-0_y-2_Smoe   ------------------------------------------------------------
IRAK-0_m-1_Smoe   --------------------------FDRKCG----------------------------
IRAK-0_f_Smoe     ------------------------------------------------------------
IRAK-0_ar-2_Smoe  ------------------------------------------------------------
IRAK-0_e-1_Smoe   ------------------------------------------------------------
IRAK-0_d-1_Smoe   ------------------------------------------------------------
IRAK-0_m-2_Smoe   --------------------------FDRKCG----------------------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    -------------P------------------------------------A---------
IRAK-0_bs_Smoe    ----------------------------S-SSPPAQ---------A-------S------
IRAK-0_t-2_Smoe   ----------------------------S-LRSGKY---------V-------A------
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  ---------------------------------TR------------------S------
IRAK-0_af-2_Smoe  ------------GAMVSAISV-------R-SFDHVD---------S-------L------
IRAK-0_af-1_Smoe  ------------GAMVSAISV-------R-SFDHVD---------S-------L------
IRAK-0_e-2_Smoe   ----------------------------A-RP-PAS---------T-------P------
IRAK-0_bn_Smoe    ----------------------------QTPAPPP------------------L------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ----------------------------A-PPDPAP---------A-------T------
IRAK-0_bh_Smoe    ----------------------------DSPCFNAA---------TT------G------
IRAK-0_x_Smoe     --------------------FG-IST-------TAS---------A--------------
IRAK-0_n-1_Smoe   ------------------------------AC-MFF---------N-------Q------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   -------------------KFYSSLD--------RE---------S-------R------
IRAK-0_au-1_Smoe  ------------GPIVSAISV-------V-SVDYRG---------E-------V------
IRAK-0_au-2_Smoe  ------------GPIVSAISV-------V-SVDYRG---------E-------V------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ------------------------------AC-MFF---------N-------Q------
IRAK-0_a-1_Smoe   ------------APAFS------AFI--K-VKTGES---------K-------L------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------------HPATS-------------------------------------------
IRAK-0_ba_Smoe    ------------------------------------DSVLLTISDK-------T------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ---------------------------------H-------------------S------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ---------------------------------DDHKLVVRVVDDE-------P------
IRAK-0_t-1_Smoe   ----------------------------S-LRSGKY---------V-------A------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ---------------------------------TR------------------S------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ---------------------------------H-------------------S------
IRAK-0_ac_Smoe    ----------------------------S-T-AGLE---------A-------P------
IRAK-0_z-2_Smoe   ----------------------------A-RPPSQA---------R-------P------
IRAK-0_k_Smoe     --------------------MI-IGK----NNLPAS---------F--------------
IRAK-0_y-1_Smoe   -----------------------------------C---------T-------P------
IRAK-0_z-1_Smoe   ----------------------------A-RPPSQA---------R-------P------
IRAK-0_bq_Smoe    -------------------KFFQGIPENA-TVLGNG---------T-------L------
IRAK-0_aj_Smoe    -------------------KFFQGIAENA-TL-PSG---------S-------KGMKSKS
IRAK-0_br_Smoe    ----------------------------E-NAPA-----------A-------P------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    KPLDLSSALHNVTPAAC------MAL--C-I----K---------NCSCKGMIE------
IRAK-0_bk_Smoe    ----------------------------A-IPPEIP---------E-------A------
IRAK-0_g-2_Smoe   -------------------KFYSSLD--------RE---------S-------R------
IRAK-0_a-2_Smoe   ------------APAFS------AFI--K-VKTGTS---------K-------L------
IRAK-0_d-2_Smoe   ----------------------------GNP--NLC---------TR------D------
IRAK-0_y-2_Smoe   -----------------------------------C---------T-------P------
IRAK-0_m-1_Smoe   --------------------KL-DIT--------S-------------------------
IRAK-0_f_Smoe     ----------------------------S-T-AGLE---------A-------P------
IRAK-0_ar-2_Smoe  ----------------------------A-PPDPAP---------A-------T------
IRAK-0_e-1_Smoe   ---------------------------------PAS---------T-------P------
IRAK-0_d-1_Smoe   ----------------------------GNP--NLC---------TR------D------
IRAK-0_m-2_Smoe   --------------------KL-DIT--------S-------------------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    -------------------------IVA-VFSVAT--MAI--IIIAMV--TWKKQIN-SY
IRAK-0_bs_Smoe    ------------SSSSRDNRA-LVWRWG-LVGGAVGLCLL--LGVAGF-AIWRWRMHT-K
IRAK-0_t-2_Smoe   ----LLK----VARPRKVSKT-Q-LQAI-TLGVLVPTLFL--LIVCLG-WHCRRRNK--H
IRAK-0_as_Smoe    ------------FRFPGSSRL-N-VAAY-FAGGVAGICFVF-ICGVVF-FVLRWRWRP-R
IRAK-0_aq-2_Smoe  ------------SSGS-----------------------------------SSNRSAFYG
IRAK-0_af-2_Smoe  ------------GSNSSRTWK-VAVAAS-VSAAAA-AIAV-IIIVAIF--FCKRSRKNF-
IRAK-0_af-1_Smoe  ------------GSNSSRTWK-VAVAAS-VSAAAA-AIAV-IIIVAIF--FCKRSRKNF-
IRAK-0_e-2_Smoe   ------------GGGSGGSSN---TAAI-VAGVVVPVFLI--LGVAGL-LLVKRRRSRRR
IRAK-0_bn_Smoe    ------------FSKSRSIGS-GAIAGI-A---IG-ALAAISISIAVL-ILWRHKQVKQR
IRAK-0_be_Smoe    ---------------------------------------------------LTYMRRVL-
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ------------GKQNAGTRN-GVIAGA-VVGGAV-FCFV--CAVLGF-FLLTRRRRE-S
IRAK-0_bh_Smoe    ------------VSRHKHHLR-RLWISL-A---VG-LPVLSAITVLIY-FLRRFIAAEKR
IRAK-0_x_Smoe     ------------RSYQRQLRRRLALVLI-LVA---VILALGFAVICAY-LCLRRKED-DR
IRAK-0_n-1_Smoe   ------------GSRGGEKREVWKIALI-VV---AGFLALSGTGVLAW-LWWRKRCK-DK
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   -------------SGSGRDRI-LKLVFG-I---IGGVL--L-LGIFAF-CCVKNRHRL-T
IRAK-0_au-1_Smoe  ------------GNSTSLSSG--QIAGI-ALGSGV-ALLV-LIGFLVY--ISRRGKGKRA
IRAK-0_au-2_Smoe  ------------GNSTSLSSG--QIAGI-ALGSGV-ALLV-LIGFLVY--ISRRGKGKRA
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ------------GSRGGEKREVWKIALI-VV---AGFLALSGTGVLAW-LWWRKRCK-EK
IRAK-0_a-1_Smoe   -----------VVHNAKHSKA-GVLITA-VLGIAALTVTV--IVSAGA--YWKNKVD-FY
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    -------------PSHSPEMA--LILAF-AIGGGVTLLVV--FVVSVL-FLYYRFKS---
IRAK-0_ba_Smoe    ----------------SDSKS-D-KVYV-H----VGF----------------NRRAAAA
IRAK-0_b-1_Smoe   -------------------------------------------------------KL-GR
IRAK-0_c-2_Smoe   ------------STPA-----------------------------------STERLAS--
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------VAPTVVSVD-ESVVEM-D----RGVFMA--AAAA-----GTPRRSSFE
IRAK-0_t-1_Smoe   ----LLK----VARPRKVSKK-Q-LQAI-TLGVLVPTLFL--LIVCLG-WHCRRRNK--H
IRAK-0_b-2_Smoe   -------------TDVFQ-HITSGPVLL-VVA---AAILAGS--IC-V-CIVRTKKL-GR
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------------SSGS-----------------------------------SSNRSAFYG
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    --------------------------------------------------F-R-RRRGRR
IRAK-0_c-1_Smoe   ------------STPA-----------------------------------STERLAS--
IRAK-0_ac_Smoe    ------------G--SKSKSS-KAVAMG-VGIGA-AVLFVIL--FAVF-LIVKRQQR--R
IRAK-0_z-2_Smoe   ------------SILQNSSRN-RALVWG-LVGGAVGACVL--LAGAAF-LLWRWRRKYTK
IRAK-0_k_Smoe     ------------NGPGRRNPTGLFFIML-PLV---VTLSLGITFIGVW-ACQEYREK-LV
IRAK-0_y-1_Smoe   ------------G--LCGKRK-NVITLA-VLCVVL-VLTVV-LVAAGF-TILEFRRKKLA
IRAK-0_z-1_Smoe   ------------SILQNSSRN-RALVWG-LVGGAVGACVL--LAGAAF-LLWRWRRKYTK
IRAK-0_bq_Smoe    ------------PSNSKAKKT-LLLAIA-IP--IAGVLALL-LLVIGF-FISKRSKNV-S
IRAK-0_aj_Smoe    FFLDEFRVKGCFPLCVTGKKT-LGLAIG-IP--IAGVAALL-LLVLGY-FILKRRKKL-P
IRAK-0_br_Smoe    ------------LL-RNAAQA-SFPLGI-VVGVLAGVLVTL-VGIFVF-FCLRRRRS-LR
IRAK-0_l_Smoe     ------------GTSQSENSS-K-CVKI-GVGVSVPLVVL--FMV---------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    -----------VFSLNK-TR--NVVDQALLFSIKL-YQAG--DLPKLN--SQSRQIN-SY
IRAK-0_bk_Smoe    ------------R--KGSSSR-TGVIVG-VTAGA-VAALAAAVGVLVF-CFRTKSRQNRR
IRAK-0_g-2_Smoe   -------------SGSGRDRI-LKLVFG-I---IGGAL--L-LGIFAF-CCVKNRHRL-T
IRAK-0_a-2_Smoe   -----------VVRNANHSKT-GVLITA-VLGIAALTVTV--IVSAVA--YWKNKVD-FY
IRAK-0_d-2_Smoe   ------------CSNNYS-RS-RVIGGI-VGGLIGGIILCAGAATAIYFVFLRKKRRSYK
IRAK-0_y-2_Smoe   ------------G--LCGKRK-NVITLA-VLCVVL-VLTVV-LVAAGF-TILEFRRKKLA
IRAK-0_m-1_Smoe   ------------GVEISKSWRRIMFVLY-------V-TCFGAAAMGIL-VYLKCGAA-K-
IRAK-0_f_Smoe     ------------G--SKSKSS-KAVAIG-VGIGA-AILFVIL--FAVF-LIVKRQQR--R
IRAK-0_ar-2_Smoe  ------------GKQNAGTRN-GVIAGA-VVGGAV-FCFV--CAVLGF-FLLTRRRRE-S
IRAK-0_e-1_Smoe   ------------GGGSGGSGN---TAAI-VAGVVVPVFLI--LGVAGL-LLVKRRRSRRR
IRAK-0_d-1_Smoe   ------------CSNNNS-RS-RVIGGI-VGGLIGGILLCAAAATAIYF-----------
IRAK-0_m-2_Smoe   ------------GDEISKSWRRIMFVLY-------V-TCFGAAAVGIL-VYLKCGAA-K-


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    LKH--------------------------------------------------Y--KPSL
IRAK-0_bs_Smoe    LVG-RHR----------------------R---------------GDDADI-QR--SIEG
IRAK-0_t-2_Smoe   DDD-EGEE----------------E---------------------STLQL-SL--MAGI
IRAK-0_as_Smoe    --G-KVS---------------------------------------DSENS-VY--NMGN
IRAK-0_aq-2_Smoe  EQPPPPQ---------------------PQ---------------PQ--PKEMV--QLGW
IRAK-0_af-2_Smoe  -RA-K------------------------------------------SFSI-YS--DTVG
IRAK-0_af-1_Smoe  -RA-K------------------------------------------SFSI-YS--DTVG
IRAK-0_e-2_Smoe   RRR-G---------------------L-PR---------------VPSSEL-QR--SSRG
IRAK-0_bn_Smoe    DDE-QGMILQYIIFGVDVIVFHADS-GSDM---------------SEPLRNWE---VPQG
IRAK-0_be_Smoe    -LL-FDDN----------------D---------------------REMER--PLLLPKN
IRAK-0_bm_Smoe    -------------------------------------------------VSH--NGAYEC
IRAK-0_ar-1_Smoe  --E-KSE----------------------K-----------------CEDF-GI--IKGL
IRAK-0_bh_Smoe    FGK-NVKN------------FYFL---HLI---------------SLLLDPVET--PRHP
IRAK-0_x_Smoe     QDA-GKK------------------EI------------------PA-TRNENDFSAAPR
IRAK-0_n-1_Smoe   SRR-KLL----------------------E---------------DRDSTLERSMHSNAS
IRAK-0_am_Smoe    --------------------------------------------------------CIGG
IRAK-0_g-1_Smoe   PAA-RKK-------------------L-KEGIVCFLKQILLFYLYMADLDLQAN--IHHG
IRAK-0_au-1_Smoe  GRA-AST---------------------TS---------------RRSTDQ-QA--SFLD
IRAK-0_au-2_Smoe  GRA-AST---------------------TS---------------RRSTDQ-QA--SFLD
IRAK-0_h_Smoe     -----------------------------------------------------------G
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   SRR-KLL----------------------E---------------DRDSALERSMHSNAS
IRAK-0_a-1_Smoe   FKS-RRQR----------------S---------------------QA-IV-SG--AAQA
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    ------SK----------------T---------------------SPFD--PA--TVPR
IRAK-0_ba_Smoe    ANASTSS---------------------AG---------------STAINSVVS--RLGW
IRAK-0_b-1_Smoe   NKG-LFP------------------KL------------------GSLAHLQ--LEFKQN
IRAK-0_c-2_Smoe   --PGA-R---------------------GG---------------SK--AAEVS--HLGW
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    HTN-VL----------------------------------------CDAEL-KL--LDGK
IRAK-0_bg_Smoe    SDVGSID---------------------SR---------------ST--VPEVS--HLGW
IRAK-0_t-1_Smoe   DDD-EGEE----------------E---------------------STLQL-SL--MAGM
IRAK-0_b-2_Smoe   KKG-LFP------------------KL------------------GSLAHLQ--LEFKQN
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  EQP-PPQ---------------------PQ---------------PQ--PKEMV--QLGW
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    DDR-PKRS------------------I-AM------------------SSSSSS--GDYK
IRAK-0_c-1_Smoe   --PGA-R---------------------GG---------------SK--AAEVS--HLGW
IRAK-0_ac_Smoe    LKA-LL----------------------------------------EDEDL-KH--LEGK
IRAK-0_z-2_Smoe   LNG-RRR----------------------Y---------------HGNTEL-EG--SIEG
IRAK-0_k_Smoe     SN---KQ------------------------------------------------RLRKE
IRAK-0_y-1_Smoe   KAV-LADQ----------------E---------------------PDLELLEYEKQAKR
IRAK-0_z-1_Smoe   LNG-RRR----------------------Y---------------HGNTEL-EG--SIEG
IRAK-0_bq_Smoe    KP------------------------P-E-----------------ELDELQVT--LHRG
IRAK-0_aj_Smoe    KKQ-EPA-------------------R-E-----------------EFDELQLT--LHRG
IRAK-0_br_Smoe    IR--RKF----------------------H---------------LDTFDL--P--VIDG
IRAK-0_l_Smoe     ------------------------------------------------SEL-NL--LDGK
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    LKH----Y----------------K---------------------PS-FP-FG--AMDV
IRAK-0_bk_Smoe    LDD-QSS---------------------SL---------------RQHGEFGDS--FEGR
IRAK-0_g-2_Smoe   PAA-RKK-------------------L-KEGIVCFLKQILLFYLYMADLDLQAN--IHHG
IRAK-0_a-2_Smoe   FKS-RRQS----------------S---------------------QA-IV-SG--AAQA
IRAK-0_d-2_Smoe   AST-PSKT------------------T-AD---------------QRNGSFVQE--QPSD
IRAK-0_y-2_Smoe   KAV-LADQ----------------E---------------------LDLELLEYEKQAKR
IRAK-0_m-1_Smoe   --------------------------------------------------FGKINDSGHG
IRAK-0_f_Smoe     LKA-LL----------------------------------------EDEDL-KH--LEGK
IRAK-0_ar-2_Smoe  --E-KSE----------------------K-----------------CEDF-GI--IKGL
IRAK-0_e-1_Smoe   RRR-RRRR----------------GGL-PR---------------VPSSEL-QR--SSRG
IRAK-0_d-1_Smoe   ----------------------------------------------------------LD
IRAK-0_m-2_Smoe   --------------------------------------------------FGKI--SGHG


IRAK-0_i-1_Smoe   ---FTYHELETATKGFSDDNKLGRGAFGTVFK----------------------------
IRAK-0_bt_Smoe    VRVFNYPELLTATKAFS--AKIASGGVGTVFE----------------------------
IRAK-0_bs_Smoe    PVVFTYQDLSLATDSFSKRNKLGQGGFGTVYK----------------------------
IRAK-0_t-2_Smoe   PRRFSFQELEEVTGKFS--NCLGNGGFGNVFK----------------------------
IRAK-0_as_Smoe    PRLFTYNELSVATDSFSEENQLGQGGFGVVYK----------------------------
IRAK-0_aq-2_Smoe  GRWYSLKELDLATNGFCEDSKIGEGGYGVVFK----------------------------
IRAK-0_af-2_Smoe  IKVYSYKELYEATDGFNPTKKLGQGGFGSVYV----------------------------
IRAK-0_af-1_Smoe  IKVYSYKELYEATDGFNPTKKLGQGGFGSVYV----------------------------
IRAK-0_e-2_Smoe   PIAFSYRDLCEATEDFSDRNKLGQGGFGTVYK----------------------------
IRAK-0_bn_Smoe    IEMFSLDQISKATSGFSKECEVGCGGFGRVYR----------------------------
IRAK-0_be_Smoe    IKVFSPQVLREATDKFSSSNLISRGRRACVYR----------------------------
IRAK-0_bm_Smoe    PTDYSLDELKLATAEFDETNILGQGASGVVYR----------------------------
IRAK-0_ar-1_Smoe  HVVFSYKDLCAATRGFSVESKLGQGGFGTVYK----------------------------
IRAK-0_bh_Smoe    CSIFRLDELILATQNFSK--ELGRGGFAKVYY----------------------------
IRAK-0_x_Smoe     VVAMSPLELEVATGYYSDEMVLGKGAFGAVYK----------------------------
IRAK-0_n-1_Smoe   LIRFDMHEMKAATRNFHRTTLIGQGGYGNVYK----------------------------
IRAK-0_am_Smoe    PVTVPYRMLKSSTANFDESHKLGEGGFGAVYK----------------------------
IRAK-0_g-1_Smoe   ATIFSYHALKTATNSFSDDNKLGQGGFGVVYK----------------------------
IRAK-0_au-1_Smoe  AGIFTYQELHDATQGFSD--KLGEGGFGAVYK----------------------------
IRAK-0_au-2_Smoe  AGIFTYQELHDATQGFSD--KLGEGGFGAVYK----------------------------
IRAK-0_h_Smoe     ASYVPISDAEIVHCKLRRKHKLGEGGFGAVYK----------------------------
IRAK-0_ae-2_Smoe  ---YTLSEIDKATNGFDKEHKIGSGGFGTVYK----------------------------
IRAK-0_ab_Smoe    -RIFTWAEMERATKCFRSDLKLGTGSFGTVYK----------------------------
IRAK-0_n-2_Smoe   LIRFDMHEMKAATRNFHRTTLIGQGGYGNVYK----------------------------
IRAK-0_a-1_Smoe   PRPFNLNELEMATRNFS--KRIGSGGFGTVFE----------------------------
IRAK-0_ae-1_Smoe  -KLYTLSEIDKATNGFDKEHKIGSGGFGTVYK----------------------------
IRAK-0_ad_Smoe    LQKFSYRELKAATGSFSIENKLGQGGFGPVHK----------------------------
IRAK-0_ba_Smoe    GHWFTLRDLEAATCGFSPDNVLGEGGYGIVYR----------------------------
IRAK-0_b-1_Smoe   ATFFSFDELSRATQNFKAELMLGTGSFGTVFQ----------------------------
IRAK-0_c-2_Smoe   GHWYTLRELDAATHCFADCNVLGEGGYGIVYK----------------------------
IRAK-0_aa-1_Smoe  PMVFTFRELKTATKSFAESRLLGGGGFSTVYQ----------------------------
IRAK-0_bb_Smoe    LHMFSYNEIKNATAGFDPARLLGKGAFGKVYK----------------------------
IRAK-0_bg_Smoe    GHWYTLRDLDVATNGFAPGNVIGEGGYGVVYR----------------------------
IRAK-0_t-1_Smoe   PRRFSFQELEEVTGKFS--NCLGNGGFGSVFK----------------------------
IRAK-0_b-2_Smoe   ATFFSFDELSRATQNFKAELMLGTGSFGTVFQ----------------------------
IRAK-0_aa-2_Smoe  -MVFTFRELKTATKSFAESRLLGGGGFSTVYQ----------------------------
IRAK-0_aq-1_Smoe  GRWYSLKELDLATNGFCEDSKIGEGGYGVVFK----------------------------
IRAK-0_i-2_Smoe   ------------------------------MQ----------------------------
IRAK-0_bj_Smoe    LACYSYTDLQSATENFAPEKKIDEGKFGELYKASVVCIFFFSNLSVANRSSCSLGFFYLQ
IRAK-0_c-1_Smoe   GHWYTLRELDAATHCFADCNVLGEGGYGIVYK----------------------------
IRAK-0_ac_Smoe    PDLFTYNELKNAARNFSSENKLGQGGFGAVYK----------------------------
IRAK-0_z-2_Smoe   PVVFKYQDLSLATCNFSETNQLGQGGFGTVYK----------------------------
IRAK-0_k_Smoe     VISLSSVELRAATNNYSEEMILGRGAFGTVYK----------------------------
IRAK-0_y-1_Smoe   VKEYTQQELSLATGNFSSDMVIGKGAFGMVYK----------------------------
IRAK-0_z-1_Smoe   PVVFKYQDLSLATCNFSETNKLGQGGFGTVYK----------------------------
IRAK-0_bq_Smoe    PVTFSYDLLRRATEGFSDDHKLGEGGFGAVYK----------------------------
IRAK-0_aj_Smoe    PVTFSYDLLRRATEDFSDDKKLGEGGFGAVYK----------------------------
IRAK-0_br_Smoe    ISNFTYHELETATKGFSDINKLGRGAFGTVFK----------------------------
IRAK-0_l_Smoe     LHMFSYNEIKNATGGFDPLRLLGTGAFGKVYK----------------------------
IRAK-0_bo_Smoe    --------------ALSDDNKLGQGGFGVVYK----------------------------
IRAK-0_bf_Smoe    VHVFNYPELLTATKAFS--EKIASGGVGTVFE----------------------------
IRAK-0_bk_Smoe    SLTFDYEELKLATKEFGEQNKLGQGGFGPVYK----------------------------
IRAK-0_g-2_Smoe   ATIFSYHALKTATNSFSDDNKLGQGGFGVVYK----------------------------
IRAK-0_a-2_Smoe   PRPFNLRELEMATRNFS--KRIGSGGFGTVFE----------------------------
IRAK-0_d-2_Smoe   AYRYSFQEMKEASNNFG--NKIGSGGFGTVYY----------------------------
IRAK-0_y-2_Smoe   VKEYTQQELSLATGNFSSDMVIGKGAFGMVYK----------------------------
IRAK-0_m-1_Smoe   VVCLSASELQAATNNYCDDSILGKGSFATVYK----------------------------
IRAK-0_f_Smoe     PDLFTYNELKNATRNFSSENKLGQGGFGAVYK----------------------------
IRAK-0_ar-2_Smoe  HVVFSYKDLCAATRGFSVESKLGQGGFGTVYK----------------------------
IRAK-0_e-1_Smoe   PIAFSYRDLCEATEDFSDRNKLGQGGFGTVYK----------------------------
IRAK-0_d-1_Smoe   AYRYSFQEMKEASNNFG--NKIGSGGFGTVYY----------------------------
IRAK-0_m-2_Smoe   VICFSASELQAATNNYCDDSILGKGSFATVYK----------------------------


IRAK-0_i-1_Smoe   GV-LKDGSEVAVKQLDLHSK---QGQREFVNELSIITSIQHKNLAKLRGYCL-----DR-
IRAK-0_bt_Smoe    GI-LS----VAVKRLESFSS---QGYKQFKAE--------------------------E-
IRAK-0_bs_Smoe    AT-LNNGSQVAVKKLSLQSN---QGKREFVNEITIITGIQHRNLVRLKGYCV-----EA-
IRAK-0_t-2_Smoe   GL-LADGTEVAVKKLE-GSN---QKSKDFFAEVGILARTHHWNLVKLLGFCA-----QGP
IRAK-0_as_Smoe    AN-LKDGTQVAVKKLSLHSK---QGKQEFVNELNIITGIRHRNLAKLHGYCV-----EA-
IRAK-0_aq-2_Smoe  GF-LPDGSVVAVKNLLNNTG---QAEKEFRVEVEAIGKVRHKNLVRLLGYCA-----ES-
IRAK-0_af-2_Smoe  GN-LQDQTLVAVKQLLHQTQ---QGREAFRKEIRILSSVQHRNLVAVRGYCL-----EA-
IRAK-0_af-1_Smoe  GN-LQDQTLVAVKQLLHQTQ---QGREAFRKEIRILSSVQHRNLVAVRGYCL-----EA-
IRAK-0_e-2_Smoe   AAFFGDGTVFAVKRLSVGSQ---QGKMEFVNEIDIITAIRHKNLVMLEGYCC-----EG-
IRAK-0_bn_Smoe    GN-LEDGRTVAIKQASAKSK---QGQREFRNEIQLLSRLHHRHLVRLLGFCQ-----SG-
IRAK-0_be_Smoe    AK-LPDEQQVVVKKTKL---A--------RDELLVISSASHFNIVGVTGYCF-----NR-
IRAK-0_bm_Smoe    GR-SSGGYNVAVKQLINVEFKYLVHQAGFAKEIEILSRARHKNVAGLLGFCN-----SR-
IRAK-0_ar-1_Smoe  AT-LNNGSQVAVKKLSLQSN---QGNREFVNEITIITGIQHRNLVRLKGYCV-----EA-
IRAK-0_bh_Smoe    GV-LPDGREIAAKVYFQENERLRRRRDAFLNEVEILSRVHHKNLVSLIGYCV-----ES-
IRAK-0_x_Smoe     GV-LENGQAVAIKRAIISNN---RSSELFEKELHLLTRTHHSCLVNLVGYCM-----E--
IRAK-0_n-1_Smoe   GV-LKDGTVVALKRFKNCSP---AGDEGFVHEMEMISSVRHKNLAPLLGWCIGSSRSEG-
IRAK-0_am_Smoe    --------------------------LQFLNEVKAISSVQHRNLVKLLGCSM-----EG-
IRAK-0_g-1_Smoe   GT-LPDGRRIAIKRLTTQSQ---KGKQEFLNEVKLVSSVQHRNLVKLYGCCT-----EE-
IRAK-0_au-1_Smoe  GT-LPSGTVIAVKQLVKHTQ---QIEDDFKREISIISKVRHRNLLAVIGYSL-----ES-
IRAK-0_au-2_Smoe  GT-LPSGTVIAVKQLVKHTQ---QIEDDFKREISIISKVRHRNLLAVIGYSL-----ES-
IRAK-0_h_Smoe     --------------------------LQFLNEVKAISSVQHRNLVKLLGCSM-----EG-
IRAK-0_ae-2_Smoe  GL-FDDGSVLAIKRANHTSK---QSSRHFYNEVAILSQVNHRNLLRLMGCCV-----DS-
IRAK-0_ab_Smoe    GK-LDDGTTVAIKKANNGNA---PRIQQFLNEVTILSKVNHRNLVKMLGCCI-----ER-
IRAK-0_n-2_Smoe   GV-LQDGTVVALKRFKNCSP---AGDEGFVHEMEMISSVRHKNLAPLLGWCIGSSRSEG-
IRAK-0_a-1_Smoe   GS-LSDGSRIAVKRLD-DSN---QGEKQFKAEVRAICNIHHRNLVSLRGYCS-----QK-
IRAK-0_ae-1_Smoe  GL-FDDGSVLAIKRANHTSK---QSSRHFYNEVAVLSQVNHRNLLRLMGCCV-----DS-
IRAK-0_ad_Smoe    GV-LRNGQVVAVKSLDSASL---QGEKEFQNEMAVIGSIRCSHIVGLMGYCA-----ER-
IRAK-0_ba_Smoe    GC-LGDGTPVAVKSLLNNSG---QAEKEFRVEVEAIGRVRHKNLVRLLGYCV-----EI-
IRAK-0_b-1_Smoe   GV-LDDDTPVAIKKANSTTG---PRIQQFLNEVTILSQVNHRNLVKLLGCCL-----ET-
IRAK-0_c-2_Smoe   GK-LPDGTPIAVKNLLNNRG---QAEKEFRVEVEAIGRVRHKNLVRLLGYCV-----EG-
IRAK-0_aa-1_Smoe  GK-LPDGRIVAVKKLNQGNK---QGIQQFQNEVNILSQVRHPNLVQLLGYCL-----EG-
IRAK-0_bb_Smoe    GV-LSDGTLVAIKQLNKM-G---DNTGDFVNEATLISTVQHRNLVKLYGCCT-----EG-
IRAK-0_bg_Smoe    GR-LPDDTLVAVKNLINNKG---QAEREFRVEVEAIGRVRHKNLVRLLGYCV-----EG-
IRAK-0_t-1_Smoe   GL-LADGTEVAVKKLE-GSN---QRSKDFFAEVGILARTHHWNLVKLLGFCA-----QGP
IRAK-0_b-2_Smoe   GV-LDDDTPVAIKKANSTTG---PRIQQFLNEVTILSQVNHRNLVKLLGCCL-----ET-
IRAK-0_aa-2_Smoe  GK-LPDGRIVAVKKLNQGNK---QGIQQFQNEVNILSQVRHPNLVQLLGYCL-----EG-
IRAK-0_aq-1_Smoe  GF-LPDGSVVAVKNLLNNTG---QAEKEFRVEVEAIGKVRHKNLVRLLGYCA-----ES-
IRAK-0_i-2_Smoe   GV-LKDGSEVAVKQLDLHSK---QGQREFVNELSIITSIQHKNLAKLRGYCL-----DR-
IRAK-0_bj_Smoe    GE-LSDGTKFAVKKLSSKYH--KEDHSVFASDVSSIFAVEHPNLVKLMGCCI-----EA-
IRAK-0_c-1_Smoe   GK-LPDGTPIAVKNLLNNRG---QAEKEFRVEVEAIGRVRHKNLVRLLGYCV-----EG-
IRAK-0_ac_Smoe    GV-LPNGTVVAIKELSSKSQ---QGSREFLNEVTVISSVQHRNLVKLHGCCI-----DG-
IRAK-0_z-2_Smoe   AC-LKDGTQVAVKKLSLQSS---QGRQEFVNEISIITSIQHRNLARLKGYCV-----ER-
IRAK-0_k_Smoe     GV-LQNGHQVAVKRAN--SS---RCDAMFDKELELLARTHHSCLVNLFGYCK-----E--
IRAK-0_y-1_Smoe   AR-LPSGEILAIKKGKL---GKA---ASFGGELKLLSRLHHTNLVNLIGYCK-----Q--
IRAK-0_z-1_Smoe   AC-LKDGTQVAVKKLSLQSS---QGRQEFVNEISIITSIQHRNLARLKGYCV-----ER-
IRAK-0_bq_Smoe    GT-FSDGTEIAIKKLSVASK---QWEQQFLNEVKVIGSLHSNRLL---------------
IRAK-0_aj_Smoe    GT-FGDGTEIAIKKLSVSSK---QGEQQFLNEVKVIGSVQHRNLVRLLGCCV-----EG-
IRAK-0_br_Smoe    GV-LKDGSEVAVKQLDLHSK---QGQREFVNELSIITSIQHKNLAKLRGYCL-----DR-
IRAK-0_l_Smoe     GV-LSDGTVVAIKQLN--------------------------------------------
IRAK-0_bo_Smoe    GT-LPDGRRIAIKRLTTQSQ---KGKQEFLNEVKLVSSVQHRNLVKLYGCCT-----EE-
IRAK-0_bf_Smoe    GI-LS----VAVKRLESFSS---QGYKQFKAE--------------------------E-
IRAK-0_bk_Smoe    GV-LTDGSEVAVKKLSLHSS---QGNQEFVNEVNIITGIQHRNLTRLRGYSV-----KG-
IRAK-0_g-2_Smoe   GT-LPDGRRIAIKRLTTQSQ---KGKQEFLNEVKLVSSVQHRNLVKLYGCCT-----EE-
IRAK-0_a-2_Smoe   GS-LSDGSRIAVKLLD-DSN---QGEKQFKAEVRAICNIHHRNLVTLRGYCS-----QK-
IRAK-0_d-2_Smoe   GR-LKNGREVAIKVLSATSH---QGAREFSNEVTLLSRIHHRNLVSFLGFCQ-----EG-
IRAK-0_y-2_Smoe   AR-LPSGEILAIKKGKL---GKA---ASFGGELKLLSRLHHTNLVNLIGYCK-----Q--
IRAK-0_m-1_Smoe   GV-LHNGRQVAIKQAKASTR---SG-EMFRKELKLLARTHHSCVVNLIGYCE-----Q--
IRAK-0_f_Smoe     GV-LPSGTVVAIKELSSKSQ---QGSREFLNEVTLISSVQHRNLVKLHGCCI-----DG-
IRAK-0_ar-2_Smoe  AT-LNNGSQVAVKKLSLQSN---QGNREFVNEITIITGIQHRNLVRLKGYCV-----EA-
IRAK-0_e-1_Smoe   AAFFGDGTVFAVKRLSVESQ---QGKREFVNEIDIITGIRHKNLVMLEGYCC-----EG-
IRAK-0_d-1_Smoe   GR-LKNGREVAIKVLSATSH---QGAREFSNEVTLLSRIHHRNLVSFLGFCQ-----EG-
IRAK-0_m-2_Smoe   GV-LHNGCQVAIKQAKACTR---SG-EMFRKELKLLARTHHSCVLNLIGYCE-----Q--


IRAK-0_i-1_Smoe   DDRILVYEFLENKS-LDQLLFES-----------------TTGILLDWPTRFQIVLGVAN
IRAK-0_bt_Smoe    SHYFLVYEYVANGY-KPR-----------------------------EDTRFKIVEEIAR
IRAK-0_bs_Smoe    DERLLVYEFLNKGS-LDRALFSS-----------------ESNAFLDWQSRFQIAIGIAR
IRAK-0_t-2_Smoe   RKRLLVYEYMKNGS-LERWIFEDD----------------RIPGNISWKLRFNIAIGTAR
IRAK-0_as_Smoe    NERLLVYEFLENGN-LDSALFQS-------------------SLALNWQSRFQITLGIAR
IRAK-0_aq-2_Smoe  CYRMLVYEYVDNGN-LEDWLHGFS----------------SQTQAFPWEARMKIALGTAK
IRAK-0_af-2_Smoe  EHPMLVCDYMRNGS-LDQFLHGS-------------------RGFLTWNQRRKIAIDTAF
IRAK-0_af-1_Smoe  EHPMLVCDYMRNGS-LDHFLHGS-------------------RGFLTWNQRRKIAIDTAF
IRAK-0_e-2_Smoe   NHRLIVYEFLEKGS-LDQTLFGK-------------------SLLLDWPARFQIIVGVAK
IRAK-0_bn_Smoe    KNQVLVYEFMENGN-LHDRLLGKY-----------------SGQLLDCYQRLAIAVAVAQ
IRAK-0_be_Smoe    KENFLVLEYVPNGS-LADHLFSN-------------------ASTLAWSSRLRIAVQVSS
IRAK-0_bm_Smoe    DDKFLVSEYVPGPN-LTAFLSGQ------------------RRKEFDWDKRKIVILGVAK
IRAK-0_ar-1_Smoe  DERLLVYEFLNKGS-LDRALFSS-----------------GSNVVLDWHSRFQIAIGIAR
IRAK-0_bh_Smoe    LSLIVVFEYMSGGT-VQGKLHAGT------------------QACLTWETRLTIALDAAQ
IRAK-0_x_Smoe     -EKLLVFEFMSRGS-LYDNIFCGS----------------RPDAGLQWICRIKIAAQAAR
IRAK-0_n-1_Smoe   HQRIIVYEFMSNGS-LDDHLFGK------------------FKKNLDWPTRQKIAIGTAK
IRAK-0_am_Smoe    TERLLVYEFLKNNS-LENALFG------------------AVEKPLSWETRHNILLGTAR
IRAK-0_g-1_Smoe   SERLLVYELLENNS-LSRVLFQ------------------G-NLCLSWEQRYNVILGVAR
IRAK-0_au-1_Smoe  DVPMLVCEFIPNGS-LDKWLFRR------------------RENALSWEARRAVAIGVAC
IRAK-0_au-2_Smoe  DVPMLVCEFIPNGS-LDKWLFRR------------------RENALSWEARRAIAIGVAC
IRAK-0_h_Smoe     TERLLVYELLKNNS-LENALFG------------------PVEKPLSWETRHNILLGTAR
IRAK-0_ae-2_Smoe  DVPILVYEYIPNGN-LFEHLHK-------------------RPGVLSWSNRLTIAIETAE
IRAK-0_ab_Smoe    EVPLLVYEFVPRGT-LYEHLHR-------------------RGDTLSWKNRLRIATETAE
IRAK-0_n-2_Smoe   HQRIIVYEFMSNGS-LDDHLFGK------------------FKKNLDWPTRQKIAIGTAK
IRAK-0_a-1_Smoe   PHHFLVYDYVHNGS-LDRWLFDSS----------------K-AKSLDWNRRFLIVQDIAR
IRAK-0_ae-1_Smoe  DVPILVYEYIPNGN-LFEHLHK-------------------RPGVLSWSNRLTIAIETAE
IRAK-0_ad_Smoe    KKRLLVYEYMANRS-LQEALFHDG----------------Y-PVELDWKMRYKVILDIAQ
IRAK-0_ba_Smoe    NYRMLVYEYVDNGN-LEQWLHGPA----------------SILNSPTWEVRMKIALGTAK
IRAK-0_b-1_Smoe   DVPLLVFEFVPNGT-LFEHLQHR------------------RSSILSWERRLQIAIETAE
IRAK-0_c-2_Smoe   CHRMLVYEYVDNGN-LEQWLHGPI----------------SRTKSLTWEARMKIVLGTAK
IRAK-0_aa-1_Smoe  RDLLLVYEFVLNGT-LADHLHGE------------------KGNGLSLETRITIALETAQ
IRAK-0_bb_Smoe    NNWILVFEFMENNN-LHQALLSKYFNLVLPSSSMYSVGPSGRNIHLSWPTRFNICIGVAR
IRAK-0_bg_Smoe    NYRMLVYEYVDNGN-LEQWLHGPV----------------ALSKTPGWDARMKIVLGTAK
IRAK-0_t-1_Smoe   RKRLLVYEYMKNGS-LERWIFEDD----------------RIPGNISWKVRFNIAIGTAR
IRAK-0_b-2_Smoe   EVPLLVFEFVPNGT-LFEHLQHR------------------RSSILSWERRLQIAIETAE
IRAK-0_aa-2_Smoe  RDLLLVYEFVLNGT-LADHLHGE------------------KGNGLSLETRITIALETAQ
IRAK-0_aq-1_Smoe  CYRMLVYEYVDNGN-LEDWLHGFS----------------SQTQAFPWEARMKIALGTAK
IRAK-0_i-2_Smoe   DDRILVYEFLENKS-LDQLLFES-----------------ATGILLDWPTRFQIVLGVAN
IRAK-0_bj_Smoe    DEQFLLYEFLENGRPLSRLLFNPD-----------------NGECLSWQTRMTIAIGIAR
IRAK-0_c-1_Smoe   CHRMLVYEYVDNGN-LEQWLHGPI----------------SRTKSLTWEARMKIVLGTAK
IRAK-0_ac_Smoe    DHRLLVYEFLENNS-LHHVL--------------------------------LICLGIAR
IRAK-0_z-2_Smoe   DQRLLVYEFLNNGS-LDRALFSP-----------------K-TSTLNWTSRFHIVTGVAR
IRAK-0_k_Smoe     -ENVLVFEFMSRGT-VHDNIFQSP---------------TSRSGPLEWVSRIRIAAQAAR
IRAK-0_y-1_Smoe   -EKQLVFEFMANGS-LYDCLFVK-------------------NIKLDWSTRLKIAIQAAH
IRAK-0_z-1_Smoe   DQRLLVYEFLNNGS-LDRALFSP-----------------K-TSTLNWTSRFHIVTGVAR
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    SERLLVYEFLKNNS-LEKALLDDMLS-------------EEETPRLSLTTRYNILLGTAR
IRAK-0_br_Smoe    DDRILVYEFLENKS-LDQLLFES-----------------ATGILLDWPTRFQIAW----
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    SERLLVYELLENNS-LSRVLFQ------------------G-NLCLSWEQRYNVILGVAR
IRAK-0_bf_Smoe    SHYFLIYEYVANGS-LDKWIYKP-------------------REELNWDTRFKIVEEIAR
IRAK-0_bk_Smoe    DERLLVYEYLPNGS-LDRTLTNS-----------------NGKIVLDWPTRYNIAIGVAR
IRAK-0_g-2_Smoe   SERLLVYELLENNS-LSRVLFQ------------------G-NLCLSWEQRYNVILGVAR
IRAK-0_a-2_Smoe   PHHFLVYDYVHNGS-LDRWLFDSS----------------K-AKSLDWNRRFSIVQDIAR
IRAK-0_d-2_Smoe   KERILVYEFMHIGT-LRDCLYAKE----------------EDRLVLDWTARLKVLLDAAK
IRAK-0_y-2_Smoe   -EKLLVFEFMGNGS-LYDCLFVK-------------------NIKLDWSTRLKIVIQAAH
IRAK-0_m-1_Smoe   -EKLLVFEFMSRGT-LHDNLYSS--------------------HSLEWTTRIKISAQAAR
IRAK-0_f_Smoe     DHRLLVYEFLENNS-LHHVL--------------------------------LICLGIAR
IRAK-0_ar-2_Smoe  DERLLVYEFLNKGS-LDRALFSS-----------------GSNVVLDWHSRFQIAIGIAR
IRAK-0_e-1_Smoe   NHRLIVYEFLEKGS-LDQTLFGK-------------------SLLLDWPARFQIIVGVAK
IRAK-0_d-1_Smoe   RERILVYEFMHIGT-LRDCLYGKE----------------EDRLVLDWTSRLKVLLDAAK
IRAK-0_m-2_Smoe   -EKLLVFEFMSRGT-LHDNLYSS--------------------NSLEWTTRIKISAQAAR


IRAK-0_i-1_Smoe   GLAYLHEGSQKQIIHRDIKASNILLDHRLHPKISDFGISKLFNQE-K-------------
IRAK-0_bt_Smoe    GMCYLHEECSTRVLHLDIKPQNLLLDENFGVKIAEFGLSRMM------------------
IRAK-0_bs_Smoe    GLAYLHEESHVQVIHRDIKASNILLDDKLQPKISDFGISKLFDLD-K-------------
IRAK-0_t-2_Smoe   GLNYLHDDCVERIIHLDLKPENVLLDDGFQPKIADFGLSKLMDRK-E-------------
IRAK-0_as_Smoe    GLAYLHEESHFQIIHRDIKASNVLLDAKLQPKISDFGLSKLFDLD-G-------------
IRAK-0_aq-2_Smoe  ALTYLHEALEPKVVHRDIKASNILVEGDWNAKISDFGLAKLLGSE-K-------------
IRAK-0_af-2_Smoe  GLAYLHDESKHRIIHCDLKPPNILLDDDMMPRIADFGMARLYEEG-K-------------
IRAK-0_af-1_Smoe  GLAYLHDESKHRIIHCDLKPPNILLDDDLMPRIADFGMARLYEEG-K-------------
IRAK-0_e-2_Smoe   GLAYLHEESHEQVIHRDIKASNILLDKMLQPKISDFGISKLAGVE-K-------------
IRAK-0_bn_Smoe    GLDYLHSY--AVIIHRDLKPSNILLDGNLTAKISDFGISKVSPEF-D-------------
IRAK-0_be_Smoe    ALEFLHSYVEPSITHGHVSSDNILLDKSWNAKLAGFGSSRRSCVKRV-------------
IRAK-0_bm_Smoe    GLAYLHSS-GMEIIHGSLKPSNILIDDDFTPKLTDHGLYRLLQQT-S-------------
IRAK-0_ar-1_Smoe  GLAYLHEESHVQIIHRDIKASNILLDDKLQPKISDFGISKLFDLD-K-------------
IRAK-0_bh_Smoe    GVEYLHTCCIPQVMHRDLKSSNILLSDKMMAKVGDFGISKFLSPD-D-------------
IRAK-0_x_Smoe     GLEYLHKYACPAIIHRDVKSANILLDDDWNAHVSDFGLSLFGPLGSA-------------
IRAK-0_n-1_Smoe   GLAYLHNGAQPAIIHRDIKGGNILLDSEFNAKVADFGLAKFAPEG-M-------------
IRAK-0_am_Smoe    GLAYLHEDSQIRIVHRDIKPSNILLDEFYEAKIADFGLARLFESS-H-------------
IRAK-0_g-1_Smoe   GLAYLHEDSQVKIIHRDIKAGNVLLDEKFEAKIADFGLARLYSDE-R-------------
IRAK-0_au-1_Smoe  GLAYLHDESKPSIIHLDVKPGNILLDEDFNPRLADFGLARLYDEK-E-------------
IRAK-0_au-2_Smoe  GLAYLHDESKPSIIHLDVKPGNILLDEDFNPRLADFGLARLYDEK-E-------------
IRAK-0_h_Smoe     GLAYLHEDSQIRIVHRDIKPSNILLDEFYEAKIADFGLARLFESS-H-------------
IRAK-0_ae-2_Smoe  ALAYLHSAAYPPIYHRDVKSANILLDNAFTTKVADFGLSRLVPVD-V-------------
IRAK-0_ab_Smoe    ALTYLHFAASPPIYHRDVKSSNILLDEKLTAKVADFGISKLVPID-S-------------
IRAK-0_n-2_Smoe   GLAYLHNGAQPAIIHRDIKGGNILLDSEFNAKVADFGLAKFAPEG-M-------------
IRAK-0_a-1_Smoe   GLAYLHEECSSTVLHLDIKPQNVLLDESFTAKISDFGLSRMLGGD-G-------------
IRAK-0_ae-1_Smoe  ALAYLHSAAYPPIYHRDVKSANILLDNAFTTKVADFGLSRLVPVD-V-------------
IRAK-0_ad_Smoe    ALAFLHFRCEPPIIHGDIKPSNVLLDDKLCARLADFGLARVKTEA-APDVRSEDVLLNGE
IRAK-0_ba_Smoe    ALAYLHEALEPKVVHRDIKASNILLDAHWNAKISDFGLAKLLGSD-N-------------
IRAK-0_b-1_Smoe   AISYLHSSAAQPIYHRDVKSTNILLDEKFTAKVADFGISKLVSLE-A-------------
IRAK-0_c-2_Smoe   ALAYLHEALEPKVVHRDIKSSNILIDSTYNARISDFGLAKLLGAG-K-------------
IRAK-0_aa-1_Smoe  ALAYLHFYVKPPIYHRDVKTSNILLDKDFKAKVADFGLSRLTHLD-A-------------
IRAK-0_bb_Smoe    GLAYLHEESSPRIIHRDIKATNVLLDQALVAKIADFGLARLFEDH-Q-------------
IRAK-0_bg_Smoe    ALAYLHEALEPKVVHRDIKASNILLDSRWNSKVSDFGLAKLLGSE-K-------------
IRAK-0_t-1_Smoe   GLSYLHDDCVERIIHLDLKPENVLLDDGFQPKIADFGLSKLMNRK-E-------------
IRAK-0_b-2_Smoe   AISYLHSSAAQPIYHRDVKSTNILLDEKFTAKVADFGISKLVSLE-A-------------
IRAK-0_aa-2_Smoe  ALAYLHFYVKPPIYHRDVKTSNILLDKDFKAKVADFGLSRLTHLD-A-------------
IRAK-0_aq-1_Smoe  ALTYLHEALEPKVVHRDIKASNILVEGDWNAKISDFGLAKLLGSE-K-------------
IRAK-0_i-2_Smoe   GLAYLHEGSQKQIIHRDIKASNILLDHRLHPKISDFGISKLFNQE-K-------------
IRAK-0_bj_Smoe    GVNYLHEEA--HVIHGDIQASNIIIDENFTPKISDFGLTSLLPDE-D-------------
IRAK-0_c-1_Smoe   ALAYLHEALEPKVVHRDIKSSNILIDSTYNARISDFGLAKLLGAG-K-------------
IRAK-0_ac_Smoe    GLSYLHEDSKPKIVHRDIKAHNVLLDRNMTPKIADFGLAKLFQDH-E-------------
IRAK-0_z-2_Smoe   GLAYLHEESHIQIIHRDIKASNILLDDKMQPKISDFGISKLFDMD-K-------------
IRAK-0_k_Smoe     GLEYLHKYASPSIIHRDIKSANILIDFDWNAHISDFGISLCGPQDNA-------------
IRAK-0_y-1_Smoe   GLEYLHLFADPSIIHRDVKSSNILLDEGFNAHVADFGASTLGPTENS-------------
IRAK-0_z-1_Smoe   GLAYLHEESHIQIIHRDIKASNILLDDKMQPKISDFGISKLFDMD-K-------------
IRAK-0_bq_Smoe    ----------PNLLHRKLVSSS--------------------------------------
IRAK-0_aj_Smoe    GLTYLHEDSQIRIVHRDIKPSNILLDETFEAKISDFGLARLYEED-E-------------
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    GLAYLHEDSQVKIIHRDIKAGNVLLDEKFEAKIADFGLARLYSDE-R-------------
IRAK-0_bf_Smoe    GMCYLHEECSTRVLHLDIKPQNLLLDENFGVKIAEFGLSRMM------------------
IRAK-0_bk_Smoe    GLAYLHEESQIQIIHRDIKASNILLDKDLTPKISDFGISKLFDQD-R-------------
IRAK-0_g-2_Smoe   GLAYLHEDSQVKIIHRDIKAGNVLLDEKFEAKIADFGLARLYSDE-R-------------
IRAK-0_a-2_Smoe   GLAYLHEECSSTVLHLDIKPQNVLLDESFTAKISDFGLSRILGGD-G-------------
IRAK-0_d-2_Smoe   GLDYLHTGCNPSIIHRDVKSSNILISDKKTGKVADFGLSKMTSEG-S-------------
IRAK-0_y-2_Smoe   GLEYLHLFADPSIIHRDVKSSNILLDEGFNAHVADFGASTLGPTENS-------------
IRAK-0_m-1_Smoe   GLEYLHRYVSPSVTHRDVKSSNILLDCDWNAKVSDFGLSVCGPQDNA-------------
IRAK-0_f_Smoe     GLSYLHEDSKPKIVHRDIKAHNVLLDRNMTPKIADFGLAKLFQDH-E-------------
IRAK-0_ar-2_Smoe  GLAYLHEESHVQIIHRDIKASNILLDDKLQPKISDFGISKLFDLD-K-------------
IRAK-0_e-1_Smoe   GLAYLHEESHEQVIHRDIKASNILLDKMLQPKISDFGISKLAGVD-R-------------
IRAK-0_d-1_Smoe   GLDYLHTGCNPSIIHRDVKSSNILISDKKTGKVADFGLSKMTSEG-S-------------
IRAK-0_m-2_Smoe   GLEYLHRYVSPSVTHRDVKSSNILLDCDWNAKVSNFGLSVCGPQDNA-------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    ------------------------------------------------------------
IRAK-0_t-2_Smoe   ------------------------------------------------------------
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  ------------------------------------------------------------
IRAK-0_af-2_Smoe  ------------------------------------------------------------
IRAK-0_af-1_Smoe  ------------------------------------------------------------
IRAK-0_e-2_Smoe   ------------------------------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ------------------------------------------------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   ------------------------------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ------------------------------------------------------------
IRAK-0_au-1_Smoe  ------------------------------------------------------------
IRAK-0_au-2_Smoe  ------------------------------------------------------------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ------------------------------------------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    AAQDHDRVKVERFVQGSSSSLRSLSCGTMVVDQTVETSAGGMRVEEEEVGFSFHNESAAA
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   ------------------------------------------------------------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------------------------------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    ------------------------------------------------------------
IRAK-0_z-2_Smoe   ------------------------------------------------------------
IRAK-0_k_Smoe     ------------------------------------------------------------
IRAK-0_y-1_Smoe   ------------------------------------------------------------
IRAK-0_z-1_Smoe   ------------------------------------------------------------
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    ------------------------------------------------------------
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    ------------------------------------------------------------
IRAK-0_g-2_Smoe   ------------------------------------------------------------
IRAK-0_a-2_Smoe   ------------------------------------------------------------
IRAK-0_d-2_Smoe   ------------------------------------------------------------
IRAK-0_y-2_Smoe   ------------------------------------------------------------
IRAK-0_m-1_Smoe   ------------------------------------------------------------
IRAK-0_f_Smoe     ------------------------------------------------------------
IRAK-0_ar-2_Smoe  ------------------------------------------------------------
IRAK-0_e-1_Smoe   ------------------------------------------------------------
IRAK-0_d-1_Smoe   ------------------------------------------------------------
IRAK-0_m-2_Smoe   ------------------------------------------------------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    ------------------------------------------------------------
IRAK-0_t-2_Smoe   ------------------------------------------------------------
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  ------------------------------------------------------------
IRAK-0_af-2_Smoe  ------------------------------------------------------------
IRAK-0_af-1_Smoe  ------------------------------------------------------------
IRAK-0_e-2_Smoe   ------------------------------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ------------------------------------------------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   ------------------------------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ------------------------------------------------------------
IRAK-0_au-1_Smoe  ------------------------------------------------------------
IRAK-0_au-2_Smoe  ------------------------------------------------------------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ------------------------------------------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    AAAADNTPPPPSSPRVDGACWKVESRRSLGADRNEDGTSQVVSKWWWKQQDERDETNAIV
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   ------------------------------------------------------------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------------------------------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    ------------------------------------------------------------
IRAK-0_z-2_Smoe   ------------------------------------------------------------
IRAK-0_k_Smoe     ------------------------------------------------------------
IRAK-0_y-1_Smoe   ------------------------------------------------------------
IRAK-0_z-1_Smoe   ------------------------------------------------------------
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    ------------------------------------------------------------
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    ------------------------------------------------------------
IRAK-0_g-2_Smoe   ------------------------------------------------------------
IRAK-0_a-2_Smoe   ------------------------------------------------------------
IRAK-0_d-2_Smoe   ------------------------------------------------------------
IRAK-0_y-2_Smoe   ------------------------------------------------------------
IRAK-0_m-1_Smoe   ------------------------------------------------------------
IRAK-0_f_Smoe     ------------------------------------------------------------
IRAK-0_ar-2_Smoe  ------------------------------------------------------------
IRAK-0_e-1_Smoe   ------------------------------------------------------------
IRAK-0_d-1_Smoe   ------------------------------------------------------------
IRAK-0_m-2_Smoe   ------------------------------------------------------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    ------------------------------------------------------------
IRAK-0_t-2_Smoe   ------------------------------------------------------------
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  ------------------------------------------------------------
IRAK-0_af-2_Smoe  ------------------------------------------------------------
IRAK-0_af-1_Smoe  ------------------------------------------------------------
IRAK-0_e-2_Smoe   ------------------------------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ------------------------------------------------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   ------------------------------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ------------------------------------------------------------
IRAK-0_au-1_Smoe  ------------------------------------------------------------
IRAK-0_au-2_Smoe  ------------------------------------------------------------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ------------------------------------------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    KDYTVDWLSCQVKSGRSRSRDWGDASVGNSFQGKNSKKQHRSRDVSGNLTKSREWWREEY
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   ------------------------------------------------------------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------------------------------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    ------------------------------------------------------------
IRAK-0_z-2_Smoe   ------------------------------------------------------------
IRAK-0_k_Smoe     ------------------------------------------------------------
IRAK-0_y-1_Smoe   ------------------------------------------------------------
IRAK-0_z-1_Smoe   ------------------------------------------------------------
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    ------------------------------------------------------------
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    ------------------------------------------------------------
IRAK-0_g-2_Smoe   ------------------------------------------------------------
IRAK-0_a-2_Smoe   ------------------------------------------------------------
IRAK-0_d-2_Smoe   ------------------------------------------------------------
IRAK-0_y-2_Smoe   ------------------------------------------------------------
IRAK-0_m-1_Smoe   ------------------------------------------------------------
IRAK-0_f_Smoe     ------------------------------------------------------------
IRAK-0_ar-2_Smoe  ------------------------------------------------------------
IRAK-0_e-1_Smoe   ------------------------------------------------------------
IRAK-0_d-1_Smoe   ------------------------------------------------------------
IRAK-0_m-2_Smoe   ------------------------------------------------------------


IRAK-0_i-1_Smoe   ------------------------------------------------------------
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    ------------------------------------------------------------
IRAK-0_t-2_Smoe   ------------------------------------------------------------
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  ------------------------------------------------------------
IRAK-0_af-2_Smoe  ------------------------------------------------------------
IRAK-0_af-1_Smoe  ------------------------------------------------------------
IRAK-0_e-2_Smoe   ------------------------------------------------------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  ------------------------------------------------------------
IRAK-0_bh_Smoe    ------------------------------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   ------------------------------------------------------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   ------------------------------------------------------------
IRAK-0_au-1_Smoe  ------------------------------------------------------------
IRAK-0_au-2_Smoe  ------------------------------------------------------------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ------------------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   ------------------------------------------------------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ------------------------------------------------------------
IRAK-0_ad_Smoe    LEDLCNKSRELKGGKKMSSQSRSRDLSSCSFDFSGDLSSKYQHQPQGGGGGGREWWSGDL
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-1_Smoe  ------------------------------------------------------------
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    ------------------------------------------------------------
IRAK-0_t-1_Smoe   ------------------------------------------------------------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  ------------------------------------------------------------
IRAK-0_aq-1_Smoe  ------------------------------------------------------------
IRAK-0_i-2_Smoe   ------------------------------------------------------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   ------------------------------------------------------------
IRAK-0_ac_Smoe    ------------------------------------------------------------
IRAK-0_z-2_Smoe   ------------------------------------------------------------
IRAK-0_k_Smoe     ------------------------------------------------------------
IRAK-0_y-1_Smoe   ------------------------------------------------------------
IRAK-0_z-1_Smoe   ------------------------------------------------------------
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    ------------------------------------------------------------
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    ------------------------------------------------------------
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    ------------------------------------------------------------
IRAK-0_g-2_Smoe   ------------------------------------------------------------
IRAK-0_a-2_Smoe   ------------------------------------------------------------
IRAK-0_d-2_Smoe   ------------------------------------------------------------
IRAK-0_y-2_Smoe   ------------------------------------------------------------
IRAK-0_m-1_Smoe   ------------------------------------------------------------
IRAK-0_f_Smoe     ------------------------------------------------------------
IRAK-0_ar-2_Smoe  ------------------------------------------------------------
IRAK-0_e-1_Smoe   ------------------------------------------------------------
IRAK-0_d-1_Smoe   ------------------------------------------------------------
IRAK-0_m-2_Smoe   ------------------------------------------------------------


IRAK-0_i-1_Smoe   ---------------------------------------------G--FTSTVIAGTMGY
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    ---------------------------------------------GFGFTSTKVAGTLGY
IRAK-0_t-2_Smoe   ----------------------------------------------SQLQLTITRGTPGY
IRAK-0_as_Smoe    ---------------------------------------------E--YGVSKVAGTFGY
IRAK-0_aq-2_Smoe  ---------------------------------------------S--HVTTRVMGTFGY
IRAK-0_af-2_Smoe  ---------------------------------------------S-HVTATKMGGTIGY
IRAK-0_af-1_Smoe  ---------------------------------------------S-HVTATKMGGTIGY
IRAK-0_e-2_Smoe   ---------------------------------------------E--NTTTRVAGTVGY
IRAK-0_bn_Smoe    ---------------------------------------------T--HVSTKPAGTAGY
IRAK-0_be_Smoe    ----------------------------------------------G---------S---
IRAK-0_bm_Smoe    ---------------------------------------------S--QA--RDVRNAVY
IRAK-0_ar-1_Smoe  ---------------------------------------------GFGFTSTKVAGTLGY
IRAK-0_bh_Smoe    ------------------------------------------------DISNSVKGTPGY
IRAK-0_x_Smoe     ---------------------------------------------T-HLSNMTIVGTPGY
IRAK-0_n-1_Smoe   ---------------------------------------------T--HMTTGVAGTQGY
IRAK-0_am_Smoe    ---------------------------------------------QLEVLTTKAAGTYGY
IRAK-0_g-1_Smoe   -----------------------------------------------S-INTQIAGTLGY
IRAK-0_au-1_Smoe  ---------------------------------------------S-HVTATRLKGTAGY
IRAK-0_au-2_Smoe  ---------------------------------------------S-HVTATRLKGTAGY
IRAK-0_h_Smoe     ---------------------------------------------QLEVLTTKAAGTYGY
IRAK-0_ae-2_Smoe  ---------------------------------------------T-HV-STMVQGTPGY
IRAK-0_ab_Smoe    ---------------------------------------------T-HI-STTLHGTPGY
IRAK-0_n-2_Smoe   ---------------------------------------------T--HMTTGVAGTQGY
IRAK-0_a-1_Smoe   ---------------------------------------------RTDNAVTAIKGTPGY
IRAK-0_ae-1_Smoe  ---------------------------------------------T-HV-STMVQGTPGY
IRAK-0_ad_Smoe    LHWIHRRGDSGTIDFSGELNSFSRELRSRERTLSRERWSGELGSRGAVSSTTSMRGTVCY
IRAK-0_ba_Smoe    ---------------------------------------------S--HVKTRVMGTFGY
IRAK-0_b-1_Smoe   ---------------------------------------------T-HV-STTVHGTPGY
IRAK-0_c-2_Smoe   ---------------------------------------------S--HVTTRVMGTFGY
IRAK-0_aa-1_Smoe  ---------------------------------------------T-HI-STAPQGTPGY
IRAK-0_bb_Smoe    ---------------------------------------------S--HISTRVAGT---
IRAK-0_bg_Smoe    ---------------------------------------------S--HVTTRVMGTFGY
IRAK-0_t-1_Smoe   ----------------------------------------------SQLQLTITRGTPGY
IRAK-0_b-2_Smoe   ---------------------------------------------T-HV-STTVHGTPGY
IRAK-0_aa-2_Smoe  ---------------------------------------------T-HI-STAPQGTPGY
IRAK-0_aq-1_Smoe  ---------------------------------------------S--HVTTRVMGTFGY
IRAK-0_i-2_Smoe   ---------------------------------------------G--FTSTVIAGTMGY
IRAK-0_bj_Smoe    ---------------------------------------------S--YINSRFSGTLGY
IRAK-0_c-1_Smoe   ---------------------------------------------S--HVTTRVMGTFGY
IRAK-0_ac_Smoe    ---------------------------------------------T--HVSTRVAGTIGY
IRAK-0_z-2_Smoe   ---------------------------------------------G--FTSTKVAGTVGY
IRAK-0_k_Smoe     ---------------------------------------------T-HLSNMTIVGTPGY
IRAK-0_y-1_Smoe   ----------------------------------------------THVTSTSLVGTPGY
IRAK-0_z-1_Smoe   ---------------------------------------------G--FTSTKVAGTVGY
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    ---------------------------------------------ATEIITTKVAGTYGY
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     ----------------------------------------------------RITGDVGY
IRAK-0_bo_Smoe    -----------------------------------------------S-INTQIAGTLGY
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    ---------------------------------------------T--SVDTKIAGTYGY
IRAK-0_g-2_Smoe   -----------------------------------------------S-INTQIAGTLGY
IRAK-0_a-2_Smoe   ---------------------------------------------RTDNAVTAIKGTPGY
IRAK-0_d-2_Smoe   ---------------------------------------------S--LVSTTVKGTVGY
IRAK-0_y-2_Smoe   ----------------------------------------------THVTSTSLVGTPGY
IRAK-0_m-1_Smoe   ---------------------------------------------T-HLSNLTIVGTPGY
IRAK-0_f_Smoe     ---------------------------------------------T--HVSTRVAGTIGY
IRAK-0_ar-2_Smoe  ---------------------------------------------GFGFTSTKVAGTLGY
IRAK-0_e-1_Smoe   ---------------------------------------------E--NTTTRLAGTVGY
IRAK-0_d-1_Smoe   ---------------------------------------------S--LVSTTVKGTVGY
IRAK-0_m-2_Smoe   ---------------------------------------------T-HLSNLTIVGTPGY


IRAK-0_i-1_Smoe   LAP----------------------EYV----------------LGGLLTVKADVYSFGV
IRAK-0_bt_Smoe    -----------------------------------------------RVRDKLDIYSFGI
IRAK-0_bs_Smoe    MAP----------------------EYT----------------SRGRLTAKADVFSYGI
IRAK-0_t-2_Smoe   VAP----------------------ECI----------------QEGTVTEKTDVFGFGV
IRAK-0_as_Smoe    MAP----------------------EYA----------------VHRRLSPKAELTHR--
IRAK-0_aq-2_Smoe  VAP----------------------EYA----------------STGLLNERSDVYSFGV
IRAK-0_af-2_Smoe  LAPGKKKELICRILELGFIDNSSLAEYA----------------MHYQLSDKADVYSYGV
IRAK-0_af-1_Smoe  LAPGKKKERISRVLDLGFIDISSLAEYA----------------MHYQLSDKADVYSYGV
IRAK-0_e-2_Smoe   MAP----------------------EYV----------------LRGRLSSKVDVFSFGV
IRAK-0_bn_Smoe    LDP----------------------EYF----------------LRRQLTTASDVYSFGV
IRAK-0_be_Smoe    ---------------------------------------------HNFGLKAEEVYRFGG
IRAK-0_bm_Smoe    DPP----------------------EAS----------------TGTLMSSKGDSYGFGV
IRAK-0_ar-1_Smoe  MAP----------------------EYA----------------TRGRLTTKADVFSYGI
IRAK-0_bh_Smoe    VDP----------------------EYGSFSLCHSCLYCIHRYFATNRFSEKSDVYSFGV
IRAK-0_x_Smoe     LDP----------------------EYG----------------LSMKLTSKSDVYSFGV
IRAK-0_n-1_Smoe   VAP----------------------EYV----------------LYNQLTDRSDVYSFGI
IRAK-0_am_Smoe    MTP----------------------EYA----------------LNGQLSDKIDVYSYGI
IRAK-0_g-1_Smoe   MAP----------------------EYA----------------LHGHLTDKADVFSFGI
IRAK-0_au-1_Smoe  LAP----------------------EYA----------------MHLQLSDKVDVYSFGV
IRAK-0_au-2_Smoe  LAP----------------------EYA----------------MHLQLSDKVDVYSFGV
IRAK-0_h_Smoe     MAP----------------------EYA----------------LNGQLSDKIDVYSYGI
IRAK-0_ae-2_Smoe  VDP----------------------EYH----------------QTYQLTDKSDVYSFGV
IRAK-0_ab_Smoe    IDP----------------------QYQ----------------QSYQLTDKSDVYSFGV
IRAK-0_n-2_Smoe   VAP----------------------EYV----------------LYNQLTDKSDVYSFGI
IRAK-0_a-1_Smoe   MAP----------------------EWL----------------TQAKVTKALDVYSFGI
IRAK-0_ae-1_Smoe  VDP----------------------EYH----------------QTYQLTDKSDVYSFGV
IRAK-0_ad_Smoe    AAP----------------------EYG----------------GAGILSEKSDVYSFGV
IRAK-0_ba_Smoe    VAP----------------------EYA----------------NTGLLNERSDVYSFGV
IRAK-0_b-1_Smoe   IDP----------------------QYQ----------------QNYQLTDKSDVYSFGV
IRAK-0_c-2_Smoe   VAP----------------------EYA----------------NTGLLNERSDVYSFGV
IRAK-0_aa-1_Smoe  LDP----------------------DYH----------------ESYQLTDKSDVYSFGV
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    VAP----------------------EYA----------------NTGLLNERSDVYSFGV
IRAK-0_t-1_Smoe   VAP----------------------ECI----------------QEGTVTEKTDVFGFGV
IRAK-0_b-2_Smoe   IDP----------------------QYQ----------------QNYQLTDKSDVYSFGV
IRAK-0_aa-2_Smoe  LDP----------------------DYH----------------ESYQLTDKSDVYSFGV
IRAK-0_aq-1_Smoe  VAP----------------------EYA----------------STGLLNERSDVYSFGV
IRAK-0_i-2_Smoe   LAP----------------------EYV----------------LGGLLTVKADVYSFGV
IRAK-0_bj_Smoe    IAP----------------------EVA-----------------QGKLTDKADVFSFGV
IRAK-0_c-1_Smoe   VAP----------------------EYA----------------NTGLLNERSDVYSFGV
IRAK-0_ac_Smoe    LSP----------------------EYA----------------MRGQLTEKADVYSFGV
IRAK-0_z-2_Smoe   MAP----------------------EYA----------------TRGRLSSKADVFSFGI
IRAK-0_k_Smoe     LDP----------------------EYG----------------TSSQLTLKSDVYSFGV
IRAK-0_y-1_Smoe   VDP----------------------EYF----------------QTMQLSPKSDVYSFGV
IRAK-0_z-1_Smoe   MAP----------------------EYA----------------TRGRLSSKADVFSFGI
IRAK-0_bq_Smoe    ------------------------------------------------------------
IRAK-0_aj_Smoe    MAP----------------------EYA----------------FHGHLSEKADVFTFGV
IRAK-0_br_Smoe    ------------------------------------------------------------
IRAK-0_l_Smoe     L--------------------------------------------------PADVYSFGV
IRAK-0_bo_Smoe    MAP----------------------EYA----------------LHGHLTDKADVFSFGI
IRAK-0_bf_Smoe    -----------------------------------------------RVRDKLDIYSFGI
IRAK-0_bk_Smoe    MAP----------------------EYA----------------MGGRLTVKADVFSFGV
IRAK-0_g-2_Smoe   MAP----------------------EYA----------------LHGHLTDKADVFSFGI
IRAK-0_a-2_Smoe   MAP----------------------EWL----------------TQTKVTKALDVYSFGI
IRAK-0_d-2_Smoe   LDP----------------------EYY----------------MNQRLTEKSDVYSFGI
IRAK-0_y-2_Smoe   VDP----------------------EYF----------------QTMQISPKSDVYSFGV
IRAK-0_m-1_Smoe   LDP----------------------DYG----------------NSSQLTTTSDVYSFGV
IRAK-0_f_Smoe     LSP----------------------EYA----------------MRGQLTEKADVYSFGV
IRAK-0_ar-2_Smoe  MAP----------------------EYA----------------TRGRLTTKADVFSYGI
IRAK-0_e-1_Smoe   MAP----------------------EYV----------------LRGRLSSKADVFSFGV
IRAK-0_d-1_Smoe   LDP----------------------EYY----------------MNQRLTEKSDVYSFGI
IRAK-0_m-2_Smoe   LDP----------------------EYG----------------NSSQLTTTSDVYSFGV


IRAK-0_i-1_Smoe   LTLEIVSGQRCSDRK-D------GRLLVYSAWILHE--NNSELEIADERLD--L------
IRAK-0_bt_Smoe    LVLEVALSI-PVCLA-GGA---QS----SWRFEKLR--SGKLMEMLEEKRA-RQE-M---
IRAK-0_bs_Smoe    LVLEIASGRKCVDPA-LP---AEEELLLQLSWKLVM--ANRMSECIDKRLG--G------
IRAK-0_t-2_Smoe   LLLEIITGCKNRNLS-GDY---LK----DYLLVSNR--NGSAA--------AHLS-E---
IRAK-0_as_Smoe    --------QKP-------------------------------------------------
IRAK-0_aq-2_Smoe  LLMELITGRDPVDYS-RP---PGEVNLVDWLKVMVA--NRHSEDVADPRLH--V------
IRAK-0_af-2_Smoe  VLLEIISGRRAIDSA-AP---REEVVLVDFAQSLASISTLELVTLLDKKLE--GEGG---
IRAK-0_af-1_Smoe  VLLEIISGRRAIDSA-AP---REEVVLVDFAQSLASISTLELVTLLDKKLE--GEGG---
IRAK-0_e-2_Smoe   LVLEIISGRKCMDDT-LP---VEEEILAQWAWSLFG--AGKLEELIDPRLE--K------
IRAK-0_bn_Smoe    VLLELITGQKAIDQK-RP---E-EFNLIEWVKPRLR--NGGIRSVIDSRIA--E------
IRAK-0_be_Smoe    LVMELVTGDRSSSKA-RR---A--CEVIE-----SGK-EEMLGLVLDRRCG--SN-D---
IRAK-0_bm_Smoe    FLIQMITGQPPWFLLETV--RSAGVMLRDWVWKFFF--H---------------------
IRAK-0_ar-1_Smoe  LVLEIASGRKCVDPA-LP---AEEELLLQLSWKLVM--ANRMSECIDKRLG--G------
IRAK-0_bh_Smoe    VLLELICGRGPLDLE-LM---DQGLTLIVWFRSLVQ--SGKTREVVDLRLE--N------
IRAK-0_x_Smoe     VLLELLSGAKPMDPF-RP---A--RHIVAWAVELME--DDALHAVLDSALD--VPA----
IRAK-0_n-1_Smoe   VFLELLSGRKALVHT-PA--SDTPVPIADWAWSVMK--ETRIVDILQQPMD--KL-----
IRAK-0_am_Smoe    VILETVSGKRNRDRS-LV---DE-------------------------VL----------
IRAK-0_g-1_Smoe   LSLEIVSGRRSTDLN-QP---IERQYLLEWAWKSHE--RNEQLDLVDARLN--TVPP---
IRAK-0_au-1_Smoe  VLLELLSGRRAVELS-AP---SEQIVLVDWAHKEAEI-PDNLLDIVDRKLH--GDF----
IRAK-0_au-2_Smoe  VLLELLSGRRAVELS-AP---SEQIVLVDWAHKEAEI-PDNLLDIVDRKLH--GDF----
IRAK-0_h_Smoe     VILKTVSGKRNRDRS-LV---DE-------------------------VL----------
IRAK-0_ae-2_Smoe  VLLEMVTGRKPVDFA-RA---SKDVNLSAYSVPLIR--KGLIEEIVDPKLE--VRVSGNA
IRAK-0_ab_Smoe    VILELITGQMPVDFS-RC---ASDKNLSTFAMSVIQ--RGAISELIDKRLD--ARTP---
IRAK-0_n-2_Smoe   VFLELLSGRKALVHT-PA--SDRPVPIADWAWSVMK--ETRIVDILQQPMD--KL-----
IRAK-0_a-1_Smoe   VVLEIITGLSAVDER-MSR---QN-----------V--SSTLKVVIDQGMD--R------
IRAK-0_ae-1_Smoe  VLLEMVTGRKPVDFA-RA---SKDVNLSAYSVPLIR--KGLIEEIVDPKLE--VRVSGNA
IRAK-0_ad_Smoe    LVLVIVAGRRPLQVV-SPSVEFERANLTSWARHLVH--NGDVLELVDPSLR--GE-----
IRAK-0_ba_Smoe    LLMEMITGRDPVDYS-RP---SAEVNLVDWVKLMVA--SRRSEEVADSRLD--A------
IRAK-0_b-1_Smoe   VLLELITGQKPVDFS-RN---SSDKNLTAFSLAYIQ--SSRIEDIIDKGLE--LGDE---
IRAK-0_c-2_Smoe   LLMEVVTGRDPVDYS-RP---PSEVNLVDWLKLMVG--QRRSEEVADPNLE--P------
IRAK-0_aa-1_Smoe  VLLELISRKKAVDMT-RD---KKEINLASMALARIH--SGALHELFDPDLS--VKY----
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    LLMEVVTGRDPVDYA-RP---AGEVNLVDWLKMMVG--SRRSDEVADPRLE--E------
IRAK-0_t-1_Smoe   LLLEIITGCKNRNLS-GDY---LK----DYLLVSNR--NGSAG--------AHLS-E---
IRAK-0_b-2_Smoe   VLLELITGQKPVDFS-RN---SSDKNLTAFSLAYIQ--SSRIEDIIDKGLE--LGDE---
IRAK-0_aa-2_Smoe  VLLELISRKKAVDMT-RD---KKEINLASMALARIH--SGALHELFDPDLS--VKY----
IRAK-0_aq-1_Smoe  LLMELITGRDPVDYS-RP---PGEVNLVDWLKVMVA--NRHSEDVADPRLQ--V------
IRAK-0_i-2_Smoe   LTLEIVSGQRCSDRK-D------GRLLVHSAWILHE--NCSELEIADQRLD--L------
IRAK-0_bj_Smoe    LLLEIVSGRNNFEPD-LP---METVFLVQWTWKLYE--QGKVLELVDPLLN--N------
IRAK-0_c-1_Smoe   LLMEVVTGRDPVDYS-RP---PSEVNLVDWLKLMVG--QRRSEEVADPNLE--P------
IRAK-0_ac_Smoe    LALEIVSGRSNLDTS-LP---ADMVYLLEWAWNLYE--RKQEMDMVDKELT--D------
IRAK-0_z-2_Smoe   LALEIVSGRRCMDPT-LS---ASQELLVQMAWNMWN--AGKMVEFVDKRLD--G------
IRAK-0_k_Smoe     VLLELLSGRKPVDLS-RQ---I--QNLVAWVIDLVG--RDEWSSVLDPRLA--VPL----
IRAK-0_y-1_Smoe   VILELFTGRKAVDLG-QS---I--VGVVAWVEKVASE-FSSLVPALDMEPP--V--D---
IRAK-0_z-1_Smoe   LALEIVSGRRCMDPT-LS---ASQELLVQMAWNMWN--AGKMVEFVDKRLD--G------
IRAK-0_bq_Smoe    --------------------------------------------------------N---
IRAK-0_aj_Smoe    VVLETLAGRKNRDVT-LP---GPEQYLLEWAWQLHS--DGLLANLLDPKLV--RSSS---
IRAK-0_br_Smoe    --------------------------------ILHE--NSSELEIADQRLD--L------
IRAK-0_l_Smoe     LVLEIVSGRTNLDTT-SED---M-----THLLDHYQ--SDKLLQLLDKRGMLRRH-G---
IRAK-0_bo_Smoe    LSLEIVSGRRSTDLN-QP---IERQYLLEWAWKSHE--RNEQLDLVDAGLN--TVPP---
IRAK-0_bf_Smoe    LVLEVASGLQAFHTC-V-------------------------------------------
IRAK-0_bk_Smoe    LLLEIICGMKCRDPR-LS---PNYDGILEWLWSFHP--GGNVEEIVDKELL--RSK----
IRAK-0_g-2_Smoe   LSLEIVSGRRSTDLN-QP---IERQYLLEWAWKSHE--RNEQLDLVDAGLN--TVPP---
IRAK-0_a-2_Smoe   VVLEIITGLSAVDER-MSR---KN-----------V--SSTLEVVIDQGMD--R------
IRAK-0_d-2_Smoe   VLLETISAREPLSPE-LF---EPESNIVQWARAALQ--KGDIKSIVDPALG--D------
IRAK-0_y-2_Smoe   VILELFTGRKAVDLG-QS---I--VGVVAWVEKVASE-FSSLVPALDMEPP--V--D---
IRAK-0_m-1_Smoe   VLLELMSGQKPIDLS-RE---I--QSLVAWVLDLVE--RDEWSSVLDARLA--VPL----
IRAK-0_f_Smoe     LALEIVSGRSNLDTS-VP---ADMVYLLEWAWNLYE--RKQEMDMVDKELT--D------
IRAK-0_ar-2_Smoe  LVLEIASGRKCVDPA-LP---AEEELLLQLSWKLVM--ANRMSECIDKRLG--G------
IRAK-0_e-1_Smoe   LVLEIISGRKCMDDT-LP---VEEEILAQWAWSLFG--AGKLEELIDPRLE--K------
IRAK-0_d-1_Smoe   VLLETISAREPLSPE-LF---EPESNIVQWARAALQ--KGDIKSIVDPALG--D------
IRAK-0_m-2_Smoe   VLLELMSGQKPIDLS-RE---I--QSLVAWVLDLVE--RDEWSSVLDARLA--VPL----


IRAK-0_i-1_Smoe   --EHNSEEILRVIQVALACTHENSASRPSMGDAVAMLSGYKQVIIAPRS---HDVYL-D-
IRAK-0_bt_Smoe    ---EATSKAEKLLRIGVWCIQPDS--QPNCGNPLT-------------------------
IRAK-0_bs_Smoe    --DYAVDEVSRLLRVAMLCTQEHEEARPTMSDVVAMLLGYLEIGALPTQ---APFHF-G-
IRAK-0_t-2_Smoe   ----EENEKERLKNVAALCVRDDPNLRPSISKVIQMMEGVTELLEVPLE---SELNF-F-
IRAK-0_as_Smoe    ----------RALRHSRKCVRT--------------------------------------
IRAK-0_aq-2_Smoe  --KPTPRILKKALLVAIRCVDPDSLRRPKMGHVVHMLEADELPYRQEKAQ--SEKR----
IRAK-0_af-2_Smoe  --EISVAEVVDMARVAVLCTLENPSLRPRMRAVWLMLKGTMEIPDIPAM---LDTRY-N-
IRAK-0_af-1_Smoe  --EISVAEVVDMARVAVLCTLENPLLRPRMRAVWLMLKGTMEIPDIPAM---LDTRY-N-
IRAK-0_e-2_Smoe   --FYIAEEAHRATHVALLCSREFEGSRPTMSAVVAMLMGYLELEPLTTVD--SPNYF-G-
IRAK-0_bn_Smoe    --NFPEEQYLALATIALRCAAFDKSERPSIKVSLE-------------------------
IRAK-0_be_Smoe    --VTDKRAVLKLAEVGAWCMTKEAKERPTMVEVASALRQVLAI-----------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  --DYAVEEVSRLLRVAMLCTQEHEEARPTMSDVVAMLLGYLEIGALPTQ---APFHF-G-
IRAK-0_bh_Smoe    --TYNLESMQRVVDTANSCIESDPSNRPDMSTIVGELKEALWLQRQQLSP--TDKMI-VP
IRAK-0_x_Smoe     ----ASGPLYRAVELALECTKVSGKERPSMTEVAKSLEEILEELHAQEDS----------
IRAK-0_n-1_Smoe   ---GDEEVMESFILVALLCAHPQVAYRPSMAQVVKMLENDLAVPSMPERP--IPLMV-N-
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   --SFDKEQAVRVVCVGLLCTQATPSQRPSMSRVVTMICGEAKLGKVSRP---AMVEL---
IRAK-0_au-1_Smoe  ----VAEEARDMASIAILCTQRSAALRPKMQAVWLMLTGAVKVPEFLEN---LSAVL-P-
IRAK-0_au-2_Smoe  ----VAEEARDMASIAILCTQRSAALRPKMQAVWLMLTGAVKVPEFLEN---LSAVL-P-
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  ADLELLESIRAVANVAMACLAFTRDERPTMKRVLEELVAIRGSDGLIRTEW-LEGEV-I-
IRAK-0_ab_Smoe    ---EMLECVAKVANLAALCLQFDGSSRPTMKFVLEELKKAMQ------------------
IRAK-0_n-2_Smoe   ---GDEEVVESFILVALLCAHPQVAYRPSMAQVVKMLENDLAVPSMPERP--IPLMV-N-
IRAK-0_a-1_Smoe   ---TKRSQIENLIQIGLWCTKVEQSQRPSMVEVVK-------------------------
IRAK-0_ae-1_Smoe  ADLELLESIRAVANVAMACLAFTRDERPTMKRVLEELVAIRGSDGLIRTEW-LEGEV-I-
IRAK-0_ad_Smoe    ---FSREQAALCIMVALQCIQRLPASRPSMAEVVRVVSGEAQLPPLELF---SP------
IRAK-0_ba_Smoe    --KPSTRALKRALLVALRCVDPDAIKRPKMGYIVHMLESDDFPYREVEIL--IDR-----
IRAK-0_b-1_Smoe   --RAKISSIQEVANLAIRCLEFDRENRPAMRSVAEELMKIKH------------------
IRAK-0_c-2_Smoe   --KPASRALKRALLVALRCVDPDSSKRPKMGHVVHMLEADEYPYRDVSAC--NSCVT-G-
IRAK-0_aa-1_Smoe  -----WKLLTRLVEVAFRCLAAEKDDRPSMVEVVRELEQLSSMTISASSSK-KSSRF-K-
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    --KPSPRALKRALLIALRCVDPDAGKRPRMGHVVHMLEAEEFPFQDVSSL--FGSPCFAL
IRAK-0_t-1_Smoe   ----EENEKERLKNVAALCVRDDPNLRPSMSKVIQMMEGVTELLQVPLE---SELNF-F-
IRAK-0_b-2_Smoe   --RAKISSIQEVANLAIRCLEFNRENRPAMRSVAEELMK---------------------
IRAK-0_aa-2_Smoe  -----WKLLTRLVEVAFRCLAAEKDDRPSMVEVVRELEQLSGMTISSSSSK-KSSRF-K-
IRAK-0_aq-1_Smoe  --KPTPRILKKALLVAIRCVDPDSLRRPKMGHVVHMLEADELPYRQEKAQ--SEKR----
IRAK-0_i-2_Smoe   --EHNSEEILRVIQVALACTHENSASRPSMGDAVAMLSGYKQVIIAPRS---HDVYL-D-
IRAK-0_bj_Smoe    --DFPEEEVFRAIHIALLCTQDSVKSRPHMVQVRAMLTGDWEISVFPSR-----------
IRAK-0_c-1_Smoe   --KPASRALKRALLVALRCVDPDSSKRPKMGHVVHMLEADEYPYRDVSAC--NSCVT-G-
IRAK-0_ac_Smoe    ---VSQEEAARVIKVALLCSHAVASSRPAMSHVVAMLVGTSPVDVSSLR----PGY--S-
IRAK-0_z-2_Smoe   --NYVEEEVFRVMDVAILCTQEGEEYRPTMSDVVAMLMGYLEIRQPPSQ---NPLYF-G-
IRAK-0_k_Smoe     ----QPEPLFRVLKLALECTRLKGKQRPSMTQVAKTLEEVLEAIASSPPGG-GDTS----
IRAK-0_y-1_Smoe   --EEKSRILAEVLELGVCCVRPKAIDRPTMTVVASSLEKVLKHFGNPSS---AREWI-S-
IRAK-0_z-1_Smoe   --NYVEEEVFRVMDVAILCTQEGEEYRPTMSDVVAMLMGYLEIRQPPSQ---NPLYF-G-
IRAK-0_bq_Smoe    --NEQEKTLVQAIHIALMCTQASPQDRPSMSHVVAMLSGHSNVNV-PLS---ATFDI-R-
IRAK-0_aj_Smoe    --NEQERTLVQAIHIALMCTQASPQDRPSMSHVVAMLSGHSNVNV-PLS---ATFDI-Q-
IRAK-0_br_Smoe    --EHNSEEILRVIQVALACTHENSASRPSMGDAVAMLSGYKQVIIAPRS---HGAYL-D-
IRAK-0_l_Smoe     ----DVSPDARVA-----------KQRPTEPR----------------------------
IRAK-0_bo_Smoe    --SFDKEQAIRVICVGLLCTQATPSQRPSMSRVVTMICGEAKLGKVSRP---AMVEL---
IRAK-0_bf_Smoe    -----------------SCG------------RSP-------------------------
IRAK-0_bk_Smoe    --NYSQTEALRSIHIALLCTHEDEASRPSMSEVVAMFLGYLKLAPLPTK---SPWYF-G-
IRAK-0_g-2_Smoe   --SFDKEQAIRVICVGLLCTQATPSQRPSMSRVVTMICGEAKLGKVSRP---AMVEL---
IRAK-0_a-2_Smoe   ---TKRSKIERLIQIGLWCTKVEQSQRPSMVEVVK-------------------------
IRAK-0_d-2_Smoe   --APRMESLWKVGEIAMYCVEPHGVNRPTMAEVARELQEALDLEEEPVGLESSPKPH-NP
IRAK-0_y-2_Smoe   --EEKSRILAEVLELGVCCVRPKAIDRPTMTVVASSLEKVLKHFGNPSS---AREWI-S-
IRAK-0_m-1_Smoe   ----EPEPLYRAVKLALECTKASGKERPSMSHVAKTLEEVLEAVVSPQTCA-FSSV----
IRAK-0_f_Smoe     ---VSQEEAARVIKVALLCSQAVASSRPAMSHVVAMLVGTSPVDVSSLR----PGYF-S-
IRAK-0_ar-2_Smoe  --DYAVDEVSRLLRVAMLCTQEHEEARPTMSDVVAMLLGYLEIGALPTQ---APFHF-G-
IRAK-0_e-1_Smoe   --FYIAEEAHRATHVALLCSREFEGSRPTMSAVVAMLMGYLELEPLTTVD--TPNYF-G-
IRAK-0_d-1_Smoe   --APRMESLWKVGEIAMYCVEPHGVNRPTMAEVARELQEALDLEEEPVGLESSPKPH-NP
IRAK-0_m-2_Smoe   ----EPEPLYRAVKLALECTKVSGKERPSMSHVAKTLEEVLEAVVSPQTCA-FSSV----


IRAK-0_i-1_Smoe   -----------Y-LS-S------------------N--D-----T---------------
IRAK-0_bt_Smoe    ------------------------------------------------------------
IRAK-0_bs_Smoe    -----------Q-V------------------------------M---------------
IRAK-0_t-2_Smoe   --------F--A-YR-P-----------------KD--Q-----L---------------
IRAK-0_as_Smoe    ------------------------------------------------------------
IRAK-0_aq-2_Smoe  ----------------S------------------T--FG----NSPH---HH--QAPTK
IRAK-0_af-2_Smoe  -----------A-VR-A------------------L--M-----S---------------
IRAK-0_af-1_Smoe  -----------A-VR-A------------------L--M-----S---------------
IRAK-0_e-2_Smoe   -----------Q-IR-H------------------H--G-----W---------------
IRAK-0_bn_Smoe    ------------------------------------------------------------
IRAK-0_be_Smoe    ------------------------------------------------------------
IRAK-0_bm_Smoe    ------------------------------------------------------------
IRAK-0_ar-1_Smoe  -----------Q-V------------------------------M---------------
IRAK-0_bh_Smoe    -----------L-LL-L-------------------------------------------
IRAK-0_x_Smoe     ------------------------------------------------------------
IRAK-0_n-1_Smoe   -----------A-----------------------Q--E-----L---------------
IRAK-0_am_Smoe    ------------------------------------------------------------
IRAK-0_g-1_Smoe   -------------VD-G------------------V--L-----K---------------
IRAK-0_au-1_Smoe  -----------S----S------------------S--G-----G---------------
IRAK-0_au-2_Smoe  -----------S----S------------------S--G-----G---------------
IRAK-0_h_Smoe     ------------------------------------------------------------
IRAK-0_ae-2_Smoe  --------L---------------------------------------------------
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   -----------A-----------------------Q--E-----L---------------
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  --------L---------------------------------------------------
IRAK-0_ad_Smoe    ------------------------------------------------------------
IRAK-0_ba_Smoe    ------------------------------------------------------------
IRAK-0_b-1_Smoe   ------------------------------------------------------------
IRAK-0_c-2_Smoe   -----------SAAKMV------------------S--FPCTTHAGPASGKYHS-RH-KS
IRAK-0_aa-1_Smoe  --------LE-H-----------QSSGELRKQRS----------V--------------A
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    LELKMIILFSFQGRKVA------------------K--EANRTKQTESQNQMKMVQSLSK
IRAK-0_t-1_Smoe   --------F--A-YR-P-----------------KD--Q-----L---------------
IRAK-0_b-2_Smoe   ------------------------------------------------------------
IRAK-0_aa-2_Smoe  --------LE-H-----------QSSGELRKQRS----------V--------------A
IRAK-0_aq-1_Smoe  ----------------S------------------T--FG----NSPH---HH--QAPTK
IRAK-0_i-2_Smoe   -----------Y-LS-S------------------N--D-----T---------------
IRAK-0_bj_Smoe    ------------------------------------------------------------
IRAK-0_c-1_Smoe   -----------SAAKMV------------------S--FPCTTHAGPASGKYHC-RH-KS
IRAK-0_ac_Smoe    -----------A-LK-DAAPGFFSDSGGKDRSRSVDSVD-----Q---------------
IRAK-0_z-2_Smoe   -----------G-G------------------------------G---------------
IRAK-0_k_Smoe     ---------------------------------P----------L--------------S
IRAK-0_y-1_Smoe   -----------S-PW-T------------------E--T-----T---------------
IRAK-0_z-1_Smoe   -----------G-G------------------------------G---------------
IRAK-0_bq_Smoe    -----------A-MN-P------------------R--F-----Y---------------
IRAK-0_aj_Smoe    -----------A-MN-P------------------R--F-----Y---------------
IRAK-0_br_Smoe    -----------Y-LS-S------------------N--D-----T---------------
IRAK-0_l_Smoe     ------------------------------------------------------------
IRAK-0_bo_Smoe    -------------VD-G------------------V--L-----K---------------
IRAK-0_bf_Smoe    ------------------------------------------------------------
IRAK-0_bk_Smoe    -------------LR-N-----------------LRLLD-----H---------------
IRAK-0_g-2_Smoe   -------------VD-G------------------V--L-----K---------------
IRAK-0_a-2_Smoe   ------------------------------------------------------------
IRAK-0_d-2_Smoe   -----------D-QF-D------------------D--D-----V---------------
IRAK-0_y-2_Smoe   -----------S-PW-T------------------E--T-----T---------------
IRAK-0_m-1_Smoe   ------------------------------------------------------------
IRAK-0_f_Smoe     -----------A-LK-DAAPGFFSDSGGKDRSRSVDSVD-----Q---------------
IRAK-0_ar-2_Smoe  -----------L-V------------------------------M---------------
IRAK-0_e-1_Smoe   -----------Q-IR-H------------------H--G-----W---------------
IRAK-0_d-1_Smoe   -----------D-QF-D------------------D--D-----V---------------
IRAK-0_m-2_Smoe   ------------------------------------------------------------


IRAK-0_i-1_Smoe   --------DNSRLLTTSN------T------------------------F--DPGTSFST
IRAK-0_bt_Smoe    -----------------------------------------------------------L
IRAK-0_bs_Smoe    --------SSSTS-TSS-------------------------------------DYLNSM
IRAK-0_t-2_Smoe   --------SRTAASNVTY------R--SSDKL------------LNSSSS--FNAFSQSS
IRAK-0_as_Smoe    -------------TEYM------------------------------------ILIRGIP
IRAK-0_aq-2_Smoe  PAPLSRRA-DGKENEVNG------G--D----K----------------H--AIYKQNWK
IRAK-0_af-2_Smoe  --------AYERSQAT------------------------------------SDCAEAVL
IRAK-0_af-1_Smoe  --------AYERSQAT------------------------------------SDCAEAVL
IRAK-0_e-2_Smoe   --------TTTTTTTTSQ------T--G----S----------------S--YAASPLTA
IRAK-0_bn_Smoe    --------------------------------------------------------AYIV
IRAK-0_be_Smoe    ----------------------------------------------------------SM
IRAK-0_bm_Smoe    -----------------------------------------------------FH-FTRF
IRAK-0_ar-1_Smoe  --------SSSTS-TSS-------------------------------------DYLNSM
IRAK-0_bh_Smoe    --------HRS----------------M----R--------------QER--CSRIEMVS
IRAK-0_x_Smoe     ------------------------------------------------------RGEAPV
IRAK-0_n-1_Smoe   --------ASTTGTSYSG--------------S----------------V--PFYFSSSG
IRAK-0_am_Smoe    ---------------------------------------------------------EKI
IRAK-0_g-1_Smoe   --------ADTLNSSYSS-------------------------------Q--ELHSSQCI
IRAK-0_au-1_Smoe  --------STSQSVSSGN------L--AE---SSISAAFRSLRVFGRVVS--PDNFSSSK
IRAK-0_au-2_Smoe  --------STSQSVSSGN------L--AE---SSISAAFRSLRVFGRVVS--PDNFSSSK
IRAK-0_h_Smoe     ---------------------------------------------------------EKI
IRAK-0_ae-2_Smoe  ----TESFHPSEGVSY-N------------------------------SG--RSRDHSAE
IRAK-0_ab_Smoe    ------------------------------------------------------------
IRAK-0_n-2_Smoe   --------ASTTGTSYSG--------------S----------------V--PFYFSSSA
IRAK-0_a-1_Smoe   ------------------------------------------------------------
IRAK-0_ae-1_Smoe  ----TESFHPSEGVSY-N------------------------------SG--RSRDHSAE
IRAK-0_ad_Smoe    ---------------------------SPQ-----------------KIQ--EHHTVELP
IRAK-0_ba_Smoe    -----ER-KPSFSCA--G------D------------------------E--IIQQRDEQ
IRAK-0_b-1_Smoe   ----------------------------------------------------------IL
IRAK-0_c-2_Smoe   PTKVSERR-PSRAAALQG------S--R----V----------------A--VTVGILTR
IRAK-0_aa-1_Smoe  STNMEEDSPTSVQVKWPS------------------------------TH--TSPSNSRS
IRAK-0_bb_Smoe    ------------------------------------------------------------
IRAK-0_bg_Smoe    EVQVLEQHGSSSGDAHES------P--M----N----------------K--FFMKRWRK
IRAK-0_t-1_Smoe   --------SRTAALNVTY------R--SSDKL------------LNSSPS--FAAFSQSS
IRAK-0_b-2_Smoe   -----------------------------------------------------------I
IRAK-0_aa-2_Smoe  STNMEEDSPTSVQVKWPS------------------------------TH--TSPSNSRS
IRAK-0_aq-1_Smoe  PAPLSRRA-DGKENEVNG------G--D----K----------------H--AIYKQNWK
IRAK-0_i-2_Smoe   --------DNSRLLTTSN------T------------------------F--GPGTSFSI
IRAK-0_bj_Smoe    ---------------------------------------------------------PGS
IRAK-0_c-1_Smoe   PTKVSERR-PSRAAALQG------S--R----V----------------A--VTVGILTR
IRAK-0_ac_Smoe    --------PSSSSANTSY------V--FSSQAS-------------QAPL--SYQEENSI
IRAK-0_z-2_Smoe   --------TSSTSTITA------------------------------------DDTNITE
IRAK-0_k_Smoe     S-TVDVKSL--K-EIFEA-----------MVV---------------NPG--SGTVTFFL
IRAK-0_y-1_Smoe   --------SGPSTVDGPS------T-LEA---S--------------FSS--SFLAEIRL
IRAK-0_z-1_Smoe   --------TSSTSTTTA------------------------------------DDTNITE
IRAK-0_bq_Smoe    --------SSSSNSAASD------P--K----N----------------KRQEKSQTFTD
IRAK-0_aj_Smoe    --------SSSSNSAASD------P--K----N----------------RRS--KTFSTP
IRAK-0_br_Smoe    --------DSSRLLTTSN------T------------------------F--EPGTSFSI
IRAK-0_l_Smoe     ------------------------------EP------------IEQ--R--PQQQCQWQ
IRAK-0_bo_Smoe    --------ADTLNSSYSS-------------------------------Q--ELHSSQCI
IRAK-0_bf_Smoe    -----------------------------------------------------------K
IRAK-0_bk_Smoe    ---------SSNTGGS----------------S----------------N--TAETFRTE
IRAK-0_g-2_Smoe   --------ADTLNSSYSS-------------------------------Q--ELHSSQCI
IRAK-0_a-2_Smoe   ------------------------------------------------------------
IRAK-0_d-2_Smoe   --------ESSRAAAAGTPYHLDAPRNP----R--------------STM--DLSSVFAQ
IRAK-0_y-2_Smoe   --------SGPSTADGHS------T-LEA---S--------------FSS--SFLAEIRL
IRAK-0_m-1_Smoe   --QIQGEFL--AVSSWDG-----------SR----------------LPS------RRVS
IRAK-0_f_Smoe     --------PSSSSANTSY------V--FSSQAS-------------QAPL--SYQEENSI
IRAK-0_ar-2_Smoe  --------SSSTT-TSS-------------------------------------DYLNSM
IRAK-0_e-1_Smoe   --------TTTTTTTTSQ------T--G----S----------------S--YAASPLTA
IRAK-0_d-1_Smoe   --------ESSRAAAAGTPYHLDAPRNP----R--------------STM--DLSSVFAQ
IRAK-0_m-2_Smoe   --QIQGEFL--AVSSWDG-----------SR----------------LPS--RRVSELLE


IRAK-0_i-1_Smoe   ESRA
IRAK-0_bt_Smoe    IDFV
IRAK-0_bs_Smoe    DMPR
IRAK-0_t-2_Smoe   LNAR
IRAK-0_as_Smoe    IPLQ
IRAK-0_aq-2_Smoe  KYEV
IRAK-0_af-2_Smoe  LSPR
IRAK-0_af-1_Smoe  LSPR
IRAK-0_e-2_Smoe   TSAR
IRAK-0_bn_Smoe    WQLY
IRAK-0_be_Smoe    RSRR
IRAK-0_bm_Smoe    FLHV
IRAK-0_ar-1_Smoe  DMPR
IRAK-0_bh_Smoe    ASSY
IRAK-0_x_Smoe     YYAI
IRAK-0_n-1_Smoe   ELPR
IRAK-0_am_Smoe    SVCI
IRAK-0_g-1_Smoe   SSAR
IRAK-0_au-1_Smoe  AVTQ
IRAK-0_au-2_Smoe  AVTQ
IRAK-0_h_Smoe     SVCI
IRAK-0_ae-2_Smoe  ITAR
IRAK-0_ab_Smoe    PLME
IRAK-0_n-2_Smoe   EVPR
IRAK-0_a-1_Smoe   VLEI
IRAK-0_ae-1_Smoe  ITAR
IRAK-0_ad_Smoe    LLVP
IRAK-0_ba_Smoe    AHRF
IRAK-0_b-1_Smoe   SAAS
IRAK-0_c-2_Smoe   RLSS
IRAK-0_aa-1_Smoe  EIYN
IRAK-0_bb_Smoe    ---M
IRAK-0_bg_Smoe    YEVS
IRAK-0_t-1_Smoe   LNAR
IRAK-0_b-2_Smoe   SAAS
IRAK-0_aa-2_Smoe  EIYN
IRAK-0_aq-1_Smoe  KYEV
IRAK-0_i-2_Smoe   ESKA
IRAK-0_bj_Smoe    LTGP
IRAK-0_c-1_Smoe   RLSS
IRAK-0_ac_Smoe    VEAR
IRAK-0_z-2_Smoe   LEGR
IRAK-0_k_Smoe     PLEN
IRAK-0_y-1_Smoe   VSPK
IRAK-0_z-1_Smoe   LEGR
IRAK-0_bq_Smoe    PEPR
IRAK-0_aj_Smoe    PEPR
IRAK-0_br_Smoe    ESRP
IRAK-0_l_Smoe     HDRD
IRAK-0_bo_Smoe    SSAR
IRAK-0_bf_Smoe    FLAV
IRAK-0_bk_Smoe    TSSQ
IRAK-0_g-2_Smoe   SSAR
IRAK-0_a-2_Smoe   VLEI
IRAK-0_d-2_Smoe   PHAR
IRAK-0_y-2_Smoe   VSPK
IRAK-0_m-1_Smoe   ALHI
IRAK-0_f_Smoe     VEAR
IRAK-0_ar-2_Smoe  DMPR
IRAK-0_e-1_Smoe   TSAR
IRAK-0_d-1_Smoe   PHAR
IRAK-0_m-2_Smoe   TRYI