IRAKh_a-2_Smoe  MLLDAGPPKSLEFWEDVPPPPLLRPAAIPAVVFTLREMLQATNNFSYDNFIGEGGFGRVY
IRAKh_c-2_Smoe  -------------------------------------LEQATDKFNMRNLVGEGSFGQVF
IRAKh_a-1_Smoe  MLLDAGPPKSLEFWEDVPPPPLLRPAAIPAVVFTLREMLQATNNFSYDNFIGEGGFGRVY
IRAKh_c-1_Smoe  -------------------------------------LEQATDKFNMRNLVGEGSFGQVF
IRAKh_b-2_Smoe  -------------------------------------MLLATANFSSDNLLGEGGFGRVY
IRAKh_b-1_Smoe  ------------------------------------------------------------


IRAKh_a-2_Smoe  RGVLRTGKPVAIKQMDPTLSRGTQGEREFRVEVDLLSRLSHPSLVRLIGYCADRKQRMLV
IRAKh_c-2_Smoe  RGILTNGKVVAIKRMDTFAGQCAEAEKEFRIEVDLLSRMNHPHLVRLFGYCADGSQRLIV
IRAKh_a-1_Smoe  RGVLRTGKPVAIKQMDPTLSRGTQGEREFRVEVDLLSRLSHPSLVRLIGYCADRKQRMLV
IRAKh_c-1_Smoe  RGILTNGKVVAIKRMDRFAGQCAEAEKEFRIEVDLLSRMNHPHLVRLFGYCADGSQRLIV
IRAKh_b-2_Smoe  RGVLKNGQIVAVKQMEPSLSKGVQGEREFRVEVDILSRLDHSHLVKLIGYCADKGQRMLV
IRAKh_b-1_Smoe  --------------MEPSLSKGVQGEREFRVEVDILSRLDHSHLVKLIGYCADKGQRMLV
                              *:   .: .:.*:***:***:***:.*. **:*:*****  **::*

IRAKh_a-2_Smoe  YEFMTQGSLQEHLHGIV----RIKMNWQVRIRIALGSARALEYLHAGPATGNPIIHRDFK
IRAKh_c-2_Smoe  YEFMSNGSLESYFAGRCLYRSGFKLDFRRRLLISLGCAKGLAFLHAGGEDGDPIVHRDFK
IRAKh_a-1_Smoe  YEFMTQGSLQEHLHGIV----RIKMDWQVRVRIALGSARALEYLHAGPATGNPIIHRDFK
IRAKh_c-1_Smoe  YEFMSNGSLESYFAGRCLYRSGFKLDFRRRLLISLGCAKGLAFLHAGGEDGDPIVHRDFK
IRAKh_b-2_Smoe  YEFMPHGNLQEHLHGIV----RVKMDWRTRVSIARGAATALEYLHNGPATGNPVIHRDFK
IRAKh_b-1_Smoe  YEFMPHGNLQEHLHGIV----RVKMDWRTRVSIARGAATALEYLHNGPATGNPVIHRDFK
                ****.:*.*:.:: *       .*:::: *: *: *.* .* :** *   *:*::*****

IRAKh_a-2_Smoe  SSNILLDETFQAKVSDFGLAKLVPHGNKTYVSTRVLGTFGYFDPHYTATGRLTLKSDVYA
IRAKh_c-2_Smoe  SSNILLDSYFSAKISDFGFAKLLQ-RNQSHASTRVIGTFGYFDPHYTATGRLTVKADVYS
IRAKh_a-1_Smoe  SSNILLDETFQAKVSDFGLAKLVPHGNKTYVSTRVLGTFGYFDPHYTATGRLTLKSDVYA
IRAKh_c-1_Smoe  SSNILLDSYFSAKISDFGFAKLLQ-RNQSHASTRVIGTFGYFDPHYTATGRLTVKADVYS
IRAKh_b-2_Smoe  SSNILLDDKFQAKVSDFGLAKLVPYGNQTYVSTRVLGTFGYFDPQYTATGRLTLKSDVYA
IRAKh_b-1_Smoe  SSNILLDDKFQAKVSDFGLAKLVPYGNQTYVSTRVLGTFGYFDPQ------LTLKSDVYA
                *******. *.**:****:***:   *:::.****:********:      **:*:***:

IRAKh_a-2_Smoe  FGVVLLELLTGRRPVDSA-HSFTKQNLVFQVRDSLRDSRKLKKIIDPEISLES-CSWESI
IRAKh_c-2_Smoe  FGVVLLQLLTGKPAVVSFGGDDVPQNIVSWAEPCLNDKRKLRRILDKDLGSTYP--PKCA
IRAKh_a-1_Smoe  FGVVLLELLTGRRPVDSA-HSFTKQNLVFQVRDSLRDSRKLKKIIDPEISLES-CSWESI
IRAKh_c-1_Smoe  FGVVLLQLLTGKPAVVSFGGDDVPQNIVSWAEPCLSDKRKLRRILDKDLGSTYP--PKCA
IRAKh_b-2_Smoe  FGVVMLELLTGRRPVNAT-YTLRKQNLVTQVRDWLREKRKLKKILDPELRAELPWQWDSI
IRAKh_b-1_Smoe  FGVVMLELLTGRRPVNAT-YTLRKQNLVTQVQDWLREKRKLKKILDPELRAELPWQWDSI
                ****:*:****: .* :       **:*  ..  * :.***::*:* ::        ..

IRAKh_a-2_Smoe  KRFAMLAYCCVRDDDTRRPTMGECVAELEQLYLLILFYRRA-------------------
IRAKh_c-2_Smoe  HKLALLASCCLRENAEARPSMAQCVQTIEEILVECAMHL-E-------------------
IRAKh_a-1_Smoe  KRFAMLAYCCVRDDDTRRPTMGECVAELEQLYLLILFYRRA-------------------
IRAKh_c-1_Smoe  HKLALLASCCLRENAEARPSMAQCVQTIEEILVECAMHL-E-------------------
IRAKh_b-2_Smoe  RRFASLAFDCIRDDDTRRPTMSQCARELELLHLSLTLYSRSSRTSCQTRKAPWPKHVTST
IRAKh_b-1_Smoe  RRFASLAFDCIRDDDTRRPTMSQCARELELLHLSLTLYSRSS------------------
                :::* **  *:*::   **:*.:*.  :* : :   ::

IRAKh_a-2_Smoe  -------------------AT
IRAKh_c-2_Smoe  -------------------NV
IRAKh_a-1_Smoe  -------------------AT
IRAKh_c-1_Smoe  -------------------NV
IRAKh_b-2_Smoe  KGRSPRSPHHWPPRLSSFLIT
IRAKh_b-1_Smoe  -------------------RT
                                    .