NEK8_Hsap ------------------------------------------------------------
NEK8_Mmus ------------------------------------------------------------
Y39G10AR.4_Cele MSTVILCHAESVNLDTIRASDANIIRYSVGVKMTELKDMLKQYTAGRIRNLGLHIQTRDT
ZC581.1_Cele ------------------------------------------------------------
CG10951_Dmel MKKFR-AKASSLPIFNGRITDATTLTTSSLQLPLGQNTQRKQSTC---------------
Nek8b_Spur ------------------------------------------------------------
NEK8a_Spur ------------------------------------------------------------
AqueK181_Aque ------------------------------------------------------------
AqueK182_Aque MLQFC-AG----------------------------------------------------
AqueK183_Aque ------------------------------------------------------------
NEK8_Hsap ------------------------------------------------------------
NEK8_Mmus ------------------------------------------------------------
Y39G10AR.4_Cele KLRILEDMEVTKESLENAGSFVSQFFRWLISEVLIEGAFIDFLLTTPIENASQICLAV-Q
ZC581.1_Cele ------------------------------------------------------------
CG10951_Dmel -TRVLPTV---------------------------------FTITDGTTGAASTSLAEAM
Nek8b_Spur ------------------------------------------------------------
NEK8a_Spur ------------------------------------------------------------
AqueK181_Aque ------------------------------------------------------------
AqueK182_Aque ---------------------------------------------------------F-F
AqueK183_Aque ------------------------------------------------------------
NEK8_Hsap ------------------------------------------------MEKYERIRVVGR
NEK8_Mmus ------------------------------------------------MEKYERIRVVGR
Y39G10AR.4_Cele SVSKKKISVRLVSRFLSSELAPHNRRIVEIYINNEIMITNPNPRATSAQNRYERIRTVGK
ZC581.1_Cele ------------------------------------------------MDNYEKVRVVGR
CG10951_Dmel SSSKAQMPNR-------------QESLLQLSVPRETGVGVAG----PELANYEKVRVVGQ
Nek8b_Spur ------------------------------------------------------------
NEK8a_Spur ------------------------------------------------MEQYEKIKVVGR
AqueK181_Aque ------------------------------------------------------------
AqueK182_Aque NVGTKLYKVSVYTDIWGSPVD-GGEKIGTLFFDGQKLKEWNAPTL-MKLEKYERIKTVGK
AqueK183_Aque ------------------------------------------------MERYEKIRVIGQ
NEK8_Hsap GAFGIVHLCLRKADQ--KLVIIKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIEYYENF
NEK8_Mmus GAFGIVHLCLRKADQ--KLVILKQIPVEQMTKEERQAAQNECQVLKLLNHPNVIEYYENF
Y39G10AR.4_Cele GAFGSAVLYRRREDS--SLVIIKEINMYDLDSSQRRLALNEVSLLSRIEHPNIIAYYDSF
ZC581.1_Cele GAFGVCWLCRGKNDASHQKVIIKLINTHGMTEKEENSIQSEVNLLKKVQHPLIIGYIDSF
CG10951_Dmel GSFGIAILYRRKSDG--HQIVFKQINLSELSPPGRDLAMNEVDVFSKLHHPNIVSYLGSF
Nek8b_Spur --------------------------MHELNANERQMALNEIRVLSMLDHPNIISYYDSF
NEK8a_Spur GAFGTVYLCRRLHDM--KLIIIKQIPX---------------------------------
AqueK181_Aque ------------------------------------------------------------
AqueK182_Aque GAYGQAILYKRKEDE--SLVILKQINILELNKIERQNVVTEIKILAMLDHPHIISYYDNF
AqueK183_Aque GAFGKVFLCKNLGNN--NHVVIKQIPVDELPSEERKSAMNEVNVLSMLQHPNIIGYYASF
NEK8_Hsap LEDKALMIAMEYAPGGTLAEFIQKRC-------NSLLEEETILHFFVQILLALHHVHTHL
NEK8_Mmus LEDKALMIAMEYAPGGTLAEFIQKRC-------NSLLEEETILHFFVQILLALHHVHTHL
Y39G10AR.4_Cele EEEGVLMIEMEYADGGTLAQMLSRT-Q-------NLLDEEQIGDMMIQMCSAVAYLHENS
ZC581.1_Cele IMDNQLGIVMQYAEGGTLERLINDQRAIKDSNMREYFPEKTVLDYFTQILIALNHMHQKN
CG10951_Dmel IKDNTLLIEMEYADGGTLAQIIAERQG------KLHFPERYIIAVFEQISSAINYMHSEN
Nek8b_Spur EEEGTLMIEMEYADGGTLAEYLASNQG------KSEMEEREILIMFQQMVSGIRHVHDHM
NEK8a_Spur ------------XXGGTVFEYLQQRG-------NALIEEDEVLRLMAQILLSMKHVHSKQ
AqueK181_Aque ------------------------------------------------------------
AqueK182_Aque EEDGLMMIEMEFADGGYKANLIKYC-S-------AM------------------------
AqueK183_Aque VEDKSLMIAMEYAPGGTLYELIQERN-------GKHIEEETILQLFVQILVAIEHVHSLN
NEK8_Hsap ILHRDLKTQNILLDKHRMVVKIGDFGISKILSSK---SKAYTVVGTPCYISPELCEGKPY
NEK8_Mmus ILHRDLKTQNILLDKHRMVVKIGDFGISKILSSK---SKAYTVVGTPCYISPELCEGKPY
Y39G10AR.4_Cele VLHRDLKTANVFLTRD-SFVKIGDFGISKIMGTETLAQGAKTVVGTPYYISPEMCSGVSY
ZC581.1_Cele IVHRDLKPQNILMNRRKTVLKLSDFGISKELGTK---SAASTVIGTPNYLSPEICESRPY
CG10951_Dmel ILHRDLKTANVFLNRR-GIVKIGDFGISKIMNTK---IHAQTVLGTPYYFSPEMCEGKEY
Nek8b_Spur ILHRN------------------------------------------CMICPLQCEGKPY
NEK8a_Spur ILHRDLKTQNILLNRDCDVIKIGDFGISKILSSK---SKAFTVVGTPSYISPELCEGKPY
AqueK181_Aque ----DLKTANIFLTRH-GIVKLGDFGISKVLSGTH--QAADSIVGTPYYISPEICEGKQY
AqueK182_Aque ------------------------------------------------------------
AqueK183_Aque ILHRDLKPQNIMLNKKKTVVKIGDFGISKVLSSKI--TSAQTVVGTPCYISPEICEGRVY
NEK8_Hsap NQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGT--FAPISDRYSPELRQLVLSL
NEK8_Mmus NQKSDIWALGCVLYELASLKRAFEAANLPALVLKIMSGT--FAPISDRYSPELRQLVLSL
Y39G10AR.4_Cele NEKSDMWALGCILYEMCCLKKAFEGDNLPALVNSIMTCA--YTPVKGPYSAEMKMVIREL
ZC581.1_Cele NQKSDMWSLGCVLYELLQLERAFDGENLPAIVMKITRSK--QNPLGDHVSNDVKMLVENL
CG10951_Dmel DNKSDIWALGCILGEMCCLKKTFAASNLSELVTKIMAGN--YTPVPSGYTSGLRSLMSNL
Nek8b_Spur NGKSDIWALGCILYEMACRQKTFEGTNLPALVNKIMKVGH-KGPNSQR--PRVQVFVQDM
NEK8a_Spur NQKSDMWAIGCVLYELLTLRRAFEANNLPALVMKIMRGS--VAPISDRYSDQLKRLLLRM
AqueK181_Aque NSKSDIWSLGCILHEMMCLSRPFDGTNLPALVHKIVEGS--FDPIKGKYSDELKQLVS--
AqueK182_Aque -----------------------------------------------------AGI----
AqueK183_Aque RKKSDIWSLGCILYELLALRKAFEGPNFPALVLKIMQGSNALQPLSDNYTSSLCTLVHAM
.
NEK8_Hsap LSLEPAQRPPLSHIMAQ--PLCIRALLNL-----HTDVGS---VRMRR---PVQG-QRAV
NEK8_Mmus LSLEPAQRPPLSHIMAQ--PLCIRALLNI-----HTDVGS---VRMRR---PGPFVFRR-
Y39G10AR.4_Cele LQLDPQKRPSAPQALKM-----------------------------LR---P--------
ZC581.1_Cele LKTHTDKRPDVSQLLSD--PLVLPYLISI-----HCDLGR---IE--P------------
CG10951_Dmel LQVEAPRRPTASEVLVYWIPLIFRSLGKNKGYSYEDDVGGPGSDQLTA---PV-------
Nek8b_Spur LQRKPEYRPSANALDFNHIPVLMEKFIDL-----TTDVDD---EL-AA---S--------
NEK8a_Spur LHLDPDKRPTIDQVMAE--PIIFKAVIEV-----CMTMGA---VKVHPKTHPILS-S---
AqueK181_Aque ------------------------------------------------------------
AqueK182_Aque ------------------------------------------------------------
AqueK183_Aque LQRNPDDRPNIENIMAN--PVIVNALVNL-----GTDVGR---LPCVT---PA-------
NEK8_Hsap LGGRVWAPSGSTGGPHLSCRAEKSVAPSNTGSRTTSVRCRG-IPRGPVRPAIPPPLSSVY
NEK8_Mmus --------------AEKSLTPGPPIASGSTGSRATSARCRG-VPRGPVRPAIPPPLSSVY
Y39G10AR.4_Cele -------S-EN-------------------RHRHTSGSMRS-SV-------SFTTLYDLH
ZC581.1_Cele -------PPTD----------------KRKPSASLSSRLRT-YPTQSTL--RPYSLSS--
CG10951_Dmel --------P-AAAYSNVSMELELPTAQTETKQ--LMIADT-AAPHEI-LE-KRSVLYQLK
Nek8b_Spur -------TD------------------SSHRKRTRSVLYQI----DTSLPG---------
NEK8a_Spur -----RPPTGN---QR-------RSASRVSSARSSSHRCNG-SG---GLP-KPRPLSLIY
AqueK181_Aque ------------------------------------------------------------
AqueK182_Aque ------------------------------------------------------------
AqueK183_Aque ---------KSAGKRHLSLETRHG---QPGKYRQVSFFVDSYLPAAT-KEVQSSTRPLVY
NEK8_Hsap AWGGGLG-TPLRLPM--LNTEVVQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGSLLPG-
NEK8_Mmus AWGGGLS-SPLRLPM--LNTEVVQVAAGRTQKAGVTRSGRLILWEAPPLGAGGGTLLPG-
Y39G10AR.4_Cele VPTITLSSIP---DLPS-RISIKQVALSKTHTMVLTNDNELFGFGDNSCGQLGFGKF--S
ZC581.1_Cele ------------------------------------------------------------
CG10951_Dmel AFGTCFSMAPIQL--PP-KAVIVDVAMSDSHFVVVNEDGSAYAWGEGTHGQLGLTAL--E
Nek8b_Spur -----IPPIPFKIELPT-ILKIRQVAVSRTHIALVTYERVVYSWGEGSKGQLGHGDL--D
NEK8a_Spur CWGNGIP-SPLRLPLPHADTKVLQVSIGRSQKTGVTHNGRLIIWESPSIGTDSG--LPG-
AqueK181_Aque ------------------------------------------------------------
AqueK182_Aque ------------------------------------------------------------
AqueK183_Aque LWGGSLS-VPMILPQPA-EKSVTSLSVGRSHRAAITDDGKLLFWELASGSLGGTTQFSLS
NEK8_Hsap -AVEQPQP-QFISRFLEGQSG-VTIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSL
NEK8_Mmus -AVELPQP-QFVSRFLEGQSG-VTIKHVACGDLFTACLTDRGIIMTFGSGSNGCLGHGNL
Y39G10AR.4_Cele -------K-MENGRLVESLKG-RDIQSVGVGNYFSVICCDRGTLLTFGTAKNLGLGKD-A
ZC581.1_Cele ------------------------------------------------------------
CG10951_Dmel ------A-WKHYPSRMESVRN-YHVVSACAGDGFTILVTQAGSLLSCGSNAHLALGQDEQ
Nek8b_Spur -------P-RNVPTSVEALKG-KSITRVACGAGFSVFGSDNGIVMTCGDGSTGCLGHGDY
NEK8a_Spur -AVDQVVP-LYIPRYLEGQSA-VSIQNVSCGDLFVACLTDRGILMTFGSGAHGCLGHGNY
AqueK181_Aque ------------------------------------------------------------
AqueK182_Aque ------------------------------------------------------------
AqueK183_Aque SRARVKDPIIFQPQLVEGFSASVVIKKVSCGDLFTACLTDKGILMTFGSGINGCLGHGDY
NEK8_Hsap TDISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTRE-SHSCPQ
NEK8_Mmus TDISQPTIVEALLGYEMVQVACGASHVLALSTDGELFAWGRGDGGRLGLGTRE-SHNCPQ
Y39G10AR.4_Cele KDSAKPMLLEQLLRYLF-------------------------------------------
ZC581.1_Cele ---NAPTT-------HLTQLTPMPSH-----IDSGFFSSGRTSNQRTQSRS---------
CG10951_Dmel RNYHSPKLIARLADVRVEQVAAGLQHVLALSREGAVYVWGTSTCGALGLGNYQQQQKFPQ
Nek8b_Spur HSASRPRLIETLLSVDVTSISCGPEHVVGVGVDGEIFAWGKGKDGRLGLGDE--------
NEK8a_Spur QDLSQAKIVEALLGYEVALVSCGASHVMAVTNEHEVFSWGRGDNGRLGLDSQE-SVSSPQ
AqueK181_Aque ------------------------------------------------------------
AqueK182_Aque ------------------------------------------------------------
AqueK183_Aque DDVPKAKLVRAMLQYETIDVACGANHVVAVTADHTVHSWGRNENGQLGTGDTL-ACNEPK
NEK8_Hsap QVPMPPGQE------------AQRVVCGIDSSMILTVPGQALACGSNRFNKLGLDHLSLG
NEK8_Mmus QVPVAPGQE------------AQRVVCGIDSSMILTSPGRVLACGSNRFNKLGLDHLSLD
Y39G10AR.4_Cele ------------------------------------------------------------
ZC581.1_Cele ------------------------------------------------------------
CG10951_Dmel KILLSHVK-----------TKPSKIYCGPDTSAVLFANGELHVCGSNDYNKLGFQRSA--
Nek8b_Spur ------------------------------------------------------------
NEK8a_Spur AVVLPPQHR------------ARSVCCGVDCSMLITEEGVVIACGSNRCNKLGLDQGE--
AqueK181_Aque ------------------------------------------------------------
AqueK182_Aque ------------------------------------------------------------
AqueK183_Aque QVLPVEGEEGGGEGGGGGKEVISSVTCGSDCSILLTSNGDILCTGSNRHNKLCLDHTSVA
NEK8_Hsap EEPVP-----------------------------------------------------HQ
NEK8_Mmus EEPVP-----------------------------------------------------YQ
Y39G10AR.4_Cele ------------------------------------------------------------
ZC581.1_Cele ------------------------------------------------------------
CG10951_Dmel ------------------------------------------------------------
Nek8b_Spur ------------------------------------------------------------
NEK8a_Spur -----------------------------------------------------------Q
AqueK181_Aque ------------------------------------------------------------
AqueK182_Aque ------------------------------------------------------------
AqueK183_Aque -TPTPATPPDFTQTSRILSSLFQAINTKESASTSQSDSRAKPRSLLATKSSTFDQSDCPD
NEK8_Hsap QVEEALSFTLLGSAPLDQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRG-S
NEK8_Mmus QVEEALSFTPLGSAPLDQEPLLCVDLGTAHSAAITASGDCYTFGSNQHGQLGTSSRRV-S
Y39G10AR.4_Cele ------------------------------------------------------------
ZC581.1_Cele ------------------------------------------------------------
CG10951_Dmel ------KITAFKKVQLPH-KVTQACFSSTHSVFLVEGGYVYTMGRNAEGQRGIRHCNS-V
Nek8b_Spur ------------------------------------------------------------
NEK8a_Spur QIEEVFSLTQVATHPLPQLNITSAAIGTSHSAFITDKGECYTLGSNQFGQLGCRTETTTP
AqueK181_Aque ------------------------------------------------------------
AqueK182_Aque ------------------------------------------------------------
AqueK183_Aque HMERVLNFTRCKVEILEG-EVTAIAAGTNHTAFINKKGHCITSGSNAYGQLGHSHSVP-A
NEK8_Hsap RAPCKVQGLEGIKMAMVACGDAFTVAIGAESEVYSWGKGARGRLGRRDEDAGLPRP----
NEK8_Mmus RAPCRVQGLEGIKMVMVACGDAFTVAVGAEGEVYSWGKGTRGRLGRRDEDAGLPRP----
Y39G10AR.4_Cele ------------------------------------------------------------
ZC581.1_Cele ------------------------------------------------------------
CG10951_Dmel DHPTLVDSVKSRYIVKANCSDQCTIVASEDNIITVWGT-RNGLPGIGSTNCGLGLQICTP
Nek8b_Spur ------------------------------------------------------------
NEK8a_Spur RIPCKPSFPDDVTLTQVACGDMFTVAITTDDKVFSWGKGARGRIGRPLQDTSAPRQ----
AqueK181_Aque ------------------------------------------------------------
AqueK182_Aque ------------------------------------------------------------
AqueK183_Aque VVPK------LVSVTRISCGDNFTIAAIKDGRMYSWGCGRRGRLGYESEPIRAEPT----
NEK8_Hsap -----------------------------------------------VQLDETHPYTVTS
NEK8_Mmus -----------------------------------------------VQLDETHPYMVTS
Y39G10AR.4_Cele ------------------------------------------------------------
ZC581.1_Cele ------------------------------------------------------------
CG10951_Dmel NMELELGNNTAAFTNFLASVYKSELILEPVDILALFSSKEQCDRGYYVQVHDVYPLAHSV
Nek8b_Spur ------------------------------------------------------------
NEK8a_Spur -----------------------------------------------VRLVDQ-DINVLS
AqueK181_Aque ------------------------------------------------------------
AqueK182_Aque ------------------------------------------------------------
AqueK183_Aque ------------------------------------------------LMTFENTQTVQS
NEK8_Hsap VSCCHGNTLLAVRSVTDEPVPP
NEK8_Mmus VSCCHGNTLLAVRSVTDEPVPP
Y39G10AR.4_Cele ------------GFHY---TNY
ZC581.1_Cele -------------QVH---SKY
CG10951_Dmel LVLVDTTTPLIS-SYEGDYPHL
Nek8b_Spur -------------------EDL
NEK8a_Spur VSCSHSNTIIASKYVE---NEA
AqueK181_Aque --------------------GE
AqueK182_Aque -------------VVK---EKK
AqueK183_Aque IQSSHSVTMAMV---T---PLE