RSK4_Hsap M-----LPFAP---QDEPWDRE-MEV-FSGGGA---SSG--------------------E
RSK3_Hsap M------PIAQ---LLELWKKIEVE---PMEIE---TTE---------------------
RSK2_Hsap M------PLAQ---LADPWQKMAVE---SP-SD---SAE---------------------
RSK1_Hsap M------EQDPKPPRLRLWALIPWL---PRKQ------R---------------------
S6k_Dmel ------MPLAD---SQKDLRQQPQQQQQQQHVSSTSSSN--------------------N
RSK1_Mmus M------EQDPKLPRLRLRTLLPWL---LGKQ------R---------------------
RSK2_Mmus M------PLAQ---LADPWQKMAVE---SP-SD---SAE---------------------
RSK3_Mmus M------PIAQ---LLELWKKIEVE---PMETE---TAE---------------------
RSK4_Mmus M-----LPFAP---VEDPWDQEDMEV-FG-STS---SSEPQVVFTMKNAATVMREHERKE
T01H8.1a_Cele MGLQRGMPLAQ---LGEPFGITPS---SIENVS-PG-ID--------------------Q
RSK1_Spur ------------------------------------------------------------
RSK2_Spur ------------------------------------------------------------
AqueK025_Aque ------MPLAQ---S-HPWQTMKF---KEEEVN----SQ--------------------E
RSK4_Hsap VNGLKM------------VD-----------EPMEE------------------------
RSK3_Hsap -EDLNL------------DV-----------EPTTED---TAEEGKS--DSA-A------
RSK2_Hsap -NGQQI------------MD-----------EPMGE------------------------
RSK1_Hsap -PRISQ------------TS-----------LPVPG------------------------
S6k_Dmel AEQ-QCSSSGLGLQLRQRMQITSSGCSSLAVTPMEHTPTEDDESGGGNSGVTSSVTTVTS
RSK1_Mmus -SRISQ--------------------------TLPG------------------------
RSK2_Mmus -NGQQI------------MD-----------EPMGE------------------------
RSK3_Mmus -EELAL------------DV-----------EPTPED---TTEEGKG--DTTSS------
RSK4_Mmus VNDLKM------------VD-----------EPMEE------------------------
T01H8.1a_Cele CKD-HR------------MD-----------VSMRSDPTDCSSDT--TNTFHSSI-----
RSK1_Spur ------------------------------------------------------------
RSK2_Spur ------------------------------------------------------------
AqueK025_Aque VED-MV------------TD-----------QQQAGAP----------------------
RSK4_Hsap -------------------------------------------------G--EAD-----
RSK3_Hsap -------------------------------------------CKT---K--VAG-----
RSK2_Hsap -------------------------------------------------E--EIN-----
RSK1_Hsap ----------------------------------------------PG-S--GPQ-----
S6k_Dmel SQRRQQLQQVQQQSALQAALEQHHISPTADLDSARKRPTHRTLCPPPEL-MELSDSESQG
RSK1_Mmus ----------------------------------------------PG-P--GPQ-----
RSK2_Mmus -------------------------------------------------E--EIN-----
RSK3_Mmus -------------------------------------------AETQP-A--SSS-----
RSK4_Mmus -------------------------------------------------G--EPV-----
T01H8.1a_Cele -------------H-I--------------------------IQPPPNNGFRLMN-----
RSK1_Spur ------------------------------------------------------------
RSK2_Spur ------------------------------------------------------------
AqueK025_Aque ------------------------------------------------------G-----
RSK4_Hsap ----SCH-----------------DEGVVKEIPITHHVKEGY-EKADPAQFELLKVLGQG
RSK3_Hsap ----SVE-----------------EEGVVKEIDISHHVKEGF-EKADPSQFELLKVLGQG
RSK2_Hsap ----PQT-----------------EEVSIKEIAITHHVKEGH-EKADPSQFELLKVLGQG
RSK1_Hsap ----RDS-----------------DEGVLKEISITHHVKAGS-EKADPSHFELLKVLGQG
S6k_Dmel GVETGGRREGATGRSAPDLEDTEPLYETENEFELKEVIKEGH-DKADPSQFELLRVLGEG
RSK1_Mmus ----QDS-----------------DEAILKEISITHHVKAGS-EKADPSQFELLKVLGQG
RSK2_Mmus ----PQT-----------------EEGSIKEIAITHHVKEGH-EKADPSQFELLKVLGQG
RSK3_Mmus ----SAE-----------------EEGIVKEIDISNHVKEGF-EKADPSQFELLKVLGQG
RSK4_Mmus ----SCR-----------------REELVKEIPITQHVKEGY-EKADPAQFDLLKVLGQG
T01H8.1a_Cele ----WKT-----------------DSSSETEIDIGD-VRKCG-EKADPRQFELLKVLGQG
RSK1_Spur ------------------------------------------------------------
RSK2_Spur ------------------------------------------------------------
AqueK025_Aque ----GPS-----------------SNSTETEINLAHAVERGSLPKADPSQFELVKVLGQG
RSK4_Hsap SFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRTKMERDILVEVNHPFIVKLHYAF
RSK3_Hsap SYGKVFLVRKVKGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIVKLHYAF
RSK2_Hsap SFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAF
RSK1_Hsap SFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDILADVNHPFVVKLHYAF
S6k_Dmel SFGKVFLVRKIIGKDAGTLYAMKVLKKATLKVKDRVRSTNERKILADVGHAFIVRLHYAF
RSK1_Mmus SFGKVFLVRKVTRPDSGHLYAMKVLKKATLKVRDRVRTKMERDILADVNHPFVVKLHYAF
RSK2_Mmus SFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAF
RSK3_Mmus SYGKVFLVRKVTGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNHPFIVKLHYAF
RSK4_Mmus SFGKVFLVRKKTGPDAGQLYAMKVLRKASLKVRDRVRTKMERDILVEVNHPFIVKLHYAF
T01H8.1a_Cele SFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAF
RSK1_Spur ------------------------------------------------------------
RSK2_Spur ----VFLEDKISKTEGRNMYAVSLGNPTLIANLSRIKQKNQRSILMKVYHDFFSSFCYAF
AqueK025_Aque SFGKVFLVRRLVGHDAGKLYAMKVLKKATLKVRDRIRTKMERDILADVRHPFVVALEYAF
RSK4_Hsap QTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHQLGIVYRDLKPE
RSK3_Hsap QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPE
RSK2_Hsap QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPE
RSK1_Hsap QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPE
S6k_Dmel QTPGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALAMNHLHTLGIIYRDLKPE
RSK1_Mmus QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPE
RSK2_Mmus QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPE
RSK3_Mmus QTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALDHLHGLGIIYRDLKPE
RSK4_Mmus QTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLAELALALDHLHRLGIVYRDLKPE
T01H8.1a_Cele QTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHSLGIVYRDLKPE
RSK1_Spur ------------------------------------------------------------
RSK2_Spur QTEGKLYLILDFLKGGDLFTRLSKEVVFIMNEIKIYFNI---------------------
AqueK025_Aque QTEGKLYLVLEFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALHHLHGLGIVYRDLKPE
RSK4_Hsap NILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHSQSADWWSYGVL
RSK3_Hsap NILLDEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVL
RSK2_Hsap NILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVL
RSK1_Hsap NILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHSHSADWWSYGVL
S6k_Dmel NILLDEHGHIALTDFGLSKQPLDG-SKTYSFCGTVEYMAPEIVNRKGHDFAADWWSFGVL
RSK1_Mmus NILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYMAPEVVNRQGHTHSADWWSYGVL
RSK2_Mmus NILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVL
RSK3_Mmus NILLDEEGHIKITDFGLSKEATDHDKRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVL
RSK4_Mmus NILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYMAPEVVNRRGHSQSADWWSYGVL
T01H8.1a_Cele NILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVL
RSK1_Spur ------------------------------------------------------------
RSK2_Spur ---------------------------------------FQXVNDRGHSQISNYFSLSTV
AqueK025_Aque NILLDADGHIKLTDFGLSKESVD-DKKTFSFCGTVEYMAPEVVNRKGHDITADWWSFGVL
RSK4_Hsap MFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRNPANRLGS--EG
RSK3_Hsap MFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSGEAQSLLRALFKRNPCNRLGAGIDG
RSK2_Hsap MFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDG
RSK1_Hsap MFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRNPANRLGSGPDG
S6k_Dmel MYEMLTGNLPFHGQTRQETMNQILRSKLGMPENLSPEAQSLLRALFKRNPQNRLGAGAQG
RSK1_Mmus MFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSTEAQSLLRALFKRNPANRLGSGPDG
RSK2_Mmus MFEMLTGTLPFQGKDRKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDG
RSK3_Mmus MFEMLTGSLPFQGKDRKETMALILKAKLGMPQFLSAEAQSLLRALFKRNPCNRLGAGVDG
RSK4_Mmus MFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEAQSLLRMLFKRNPANRLGS--EG
T01H8.1a_Cele MFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDG
RSK1_Spur -------------------------AKLGMPQFLSAEAQSLLRMLFKRNPQNRLGAGPNG
RSK2_Spur QYEMLTGALPFQGQHRKETMALILKAKLGMPQFLSAEAQSLLRMLFKRNPQNRLGAGPNG
AqueK025_Aque MYEMLTGSLPFQGENRKATMNMILKAKLGMPQFLSPEAQSLLRVLFKRNPLNRLCYGTNG
:**.**. *: ******* *****. *** :*
RSK4_Hsap VEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTFCFDPEFTAKTPKDSPGLPASAN
RSK3_Hsap VEEIKRHPFFVTIDWNTLYRKEIKPPFKPAVGRPEDTFHFDPEFTARTPTDSPGVPPSAN
RSK2_Hsap VEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPEFTAKTPKDSPGIPPSAN
RSK1_Hsap AEEIKRHVFYSTIDWNKLYRREIKPPFKPAVAQPDDTFYFDTEFTSRTPKDSPGIPPSAG
S6k_Dmel ILDIKAHCFFATIDWVRLERKQVRPPFIPAVSR-DDAFYFDVEYTSKSPRDSPGGPISAS
RSK1_Mmus AEEIKRHIFYSTIDWNKLYRREIKPPFKPAVAQPDDTFYFDTEFTSRTPRDSPGIPPSAG
RSK2_Mmus VEEIKRHSFFSTIDWNKLYRREIHPPFKPATGRPEDTFYFDPEFTAKTPKDSPGIPPSAN
RSK3_Mmus VEEIKRHPFFVTIDWNKLYRKEIKPPFKPAVGRPEDTFHFDPEFTARTPTDSPGVPPSAN
RSK4_Mmus VEEVKRHAFFASIDWNKLYKREVQPPFRPASGKPDDTFCFDPEFTAKTPKDSPGLPASAN
T01H8.1a_Cele VEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASAN
RSK1_Spur INDIKSHAFFASILWXKLKKAELTPPFRPVIPTSDIVHYFDTEFTSRTPRXXXXXXXXXX
RSK2_Spur INDIKSHAFFASILWEVSYHNH--------------------------------------
AqueK025_Aque IDNIKAHPFFKSINWDKLYKREVMPPFKPACGSADDAFYFDSEFTSRTPKDSPGAPVSAH
::* * *: .* : . .
RSK4_Hsap AHQLFKGFSFVATSIAEEYKIT----PI------------TSANVLPIV-QING-NAAQF
RSK3_Hsap AHHLFRGFSFVASSLIQEPSQQ----DL------------HKVPVHPIVQQLHG-NNIHF
RSK2_Hsap AHQLFRGFSFVAITSDDE--SQ----AM------------QTVGVHSIVQQLHR-NSIQF
RSK1_Hsap AHQLFRGFSFVATGLMEDDGKP----RA------------PQAPLHSVVQQLHG-KNLVF
S6k_Dmel AHEIFRGFSFVAPVLLEGQCAGSNMCSTSASPLHS-IAPIPAAPVGAP-RTLPGVLPGNF
RSK1_Mmus AHQLFRGFSFVATGLMEDDGKP----RT------------TQAPLHSVVQQLHG-KNLVF
RSK2_Mmus AHQLFRGFSFVAITSDDE--SQ----AM------------QTVGVHSIVQQLHR-NSIQF
RSK3_Mmus AHHLFRGFSFVASSLVQEPSQQ----DV------------PKAPIHPIVQQLHG-NNIHF
RSK4_Mmus AHQLFKGFSFVATSIAEEYKIT----PV------------TSSNVLPIV-QING-NAAQF
T01H8.1a_Cele GHEIFRGFSFVSNAVMEERKL---I-AK---------------SVRSV---PTA-KTNPF
RSK1_Spur XXXXXXXXXXXXXXXXXXXXX------X------------XXXXXXXXXXXXXX-XXXXX
RSK2_Spur ------------------------------------------------------------
AqueK025_Aque SKELFRXFSYVAPLLGMEVDDPS-S-SSNGIKVKSGAAGVASAHMSTLGSPLPV-RTTAI
RSK4_Hsap GEVYELKED--IGVGSYSVCKRCIHATTNMEFAVKIIDK---------SKRDPSEEIEIL
RSK3_Hsap TDGYEIKED--IGVGSYSVCKRCVHKATDTEYAVKIIDK---------SKRDPSEEIEIL
RSK2_Hsap TDGYEVKED--IGVGSYSVCKRCIHKATNMEFAVKIIDK---------SKRDPTEEIEIL
RSK1_Hsap SDGYVVKET--IGVGSYSECKRCVHKATNMEYAVKVIDK---------SKRDPSEEIEIL
S6k_Dmel HAEYNLLQE--LGRGTFSVCRLCEHRASKKHYAVKVIEKAAVAAASTSTSADCWEEVEIM
RSK1_Mmus SDGYVVKET--IGVGSYSVCKRCVHKATNMEYAVKVIDK---------SKRDPSEEIEIL
RSK2_Mmus TDGYEVKED--IGVGSYSVCKRCIHKATNMEFAVKIIDK---------SKRDPTEEIEIL
RSK3_Mmus TDGYEIKED--IGVGSYSVCKRCVHKATDAEYAVKIIDK---------SKRDPSEEIEIL
RSK4_Mmus SEAYELKED--IGIGSYSVCKRCIHSASNVEFAVKIIDK---------NKRDPSEEIEIL
T01H8.1a_Cele TDDYEILEK--IGNGAHSVVHKCQMKATRRKYAVKIVKK---------AVFDATEEVDIL
RSK1_Spur XXXXXXXQD--IGLGSYSVCKRCTHKATGQDYAVKIIKK---------NTKDVREEIEIL
RSK2_Spur ------------------------------------------------------------
AqueK025_Aque NDDYDIKEDMLLGYGSYSRCVRCIHRATNQEFAVKIISKEK-------STRDVDEEIEIL
RSK4_Hsap MRYG-QHPNIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCF-SEREASDILYVISK
RSK3_Hsap LRYG-QHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYF-SEREASDVLCTITK
RSK2_Hsap LRYG-QHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFF-SEREASAVLFTITK
RSK1_Hsap LRYG-QHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFF-SEREASFVLHTIGK
S6k_Dmel LRYG-NHPNIVTLYSVYEDAGSAYLVMELLKGGELLDRILAVGQM-CESEASAVLRTIAS
RSK1_Mmus LRYG-QHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFF-SEREASFVLHTISK
RSK2_Mmus LRYG-QHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFF-SEREASAVLFTITK
RSK3_Mmus LRYG-QHPNIITLKDVYDDGKYVYLVMELMRGGELLDRILRQRCF-SEREASDVLYTIAR
RSK4_Mmus MRYG-QHPNIISLKEVFDDGKYVYLVTDLMKGGELLDRILKKKCF-SEQEASNVLYVITK
T01H8.1a_Cele LRHS-HHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLN
RSK1_Spur LRYG-HHSNVITLRDVFDDGQNVYMVMELMRGGELLDRLLKQKFL-SEREACEIMLTVTR
RSK2_Spur ------------------------------------------------------------
AqueK025_Aque LRYAPQHENIIKLRDVYDDGTYIYMVMELMRGGELLDKIISQKFF-SEKEAAAVLAILTD
RSK4_Hsap TVDYLHCQGVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFV
RSK3_Hsap TMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFV
RSK2_Hsap TVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFV
RSK1_Hsap TVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFV
S6k_Dmel AVAYLHEHGVVHRDLKPSNMIYASMRQTPETLKLCDLGFAKQLRADNGLLMTPCYTANFV
RSK1_Mmus TVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFV
RSK2_Mmus TVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFV
RSK3_Mmus TMDYLHSQGVVHRDLKPSNILYMDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFV
RSK4_Mmus TVECLHSQGVVHRDLKPSNILYMDESAHPDSIKICDFGFAKQLRGENGLLLTPCYTANFV
T01H8.1a_Cele AVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFV
RSK1_Spur TMDFLHQQKVVHRDLKPSNILYADETYSPGTLRIADFGFAKQMRADNGMLMTPCYTANFV
RSK2_Spur ---------------MTSNISFIQESGN--------------------------------
AqueK025_Aque TVSYLHLKGVVHRDLKPSNILYADPSCSPRSLRIADFGFAKQLRAENGLLMTPCYTANYV
.:*: :
RSK4_Hsap APEVLMQQGYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNW
RSK3_Hsap APEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNW
RSK2_Hsap APEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYW
RSK1_Hsap APEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNW
S6k_Dmel APEVLKRQGYDLACDIWSLGVLLYIMLSGRTPFASTPNDSPDVILKRIGSGQIDFTSSRW
RSK1_Mmus APEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNW
RSK2_Mmus APEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYW
RSK3_Mmus APEVLKRQGYDAACDVWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNW
RSK4_Mmus APEVLTQQGYDAACDIWSLGVLLYTMLAGYTPFSNGPNDTPEEILLRIGNGRFSLSGGIW
T01H8.1a_Cele APEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVW
RSK1_Spur APEVLKKQGYDAACDIWSLGVILYTMLAGFTPFVHKPDDSSKVILARIQEGKYTMNGGNW
RSK2_Spur ------------------------------------------------------------
AqueK025_Aque APEVLKKQGYDAAIDIWSLGVLLYTMLAGECPFAAGPDDGPDKILSRISEGKINLTGGNW
RSK4_Hsap DNISDGAKDLLSHMLHMDPHQRYTAEQILKHSWITHRD----------QLPNDQPK----
RSK3_Hsap DSISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWVVNRE----------YLSPNQLS----
RSK2_Hsap NSVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVHWD----------QLPQYQLN----
RSK1_Hsap NTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWVTQKD----------KLPQSQLS----
S6k_Dmel ALISVPAKELLRQMLHIVPENRPTAARILEHDWLREQFAGGVQLTEYAVAPGSQLSLGAQ
RSK1_Mmus NTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKD----------KLPQSQLS----
RSK2_Mmus NSVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVHWD----------QLPQYQLN----
RSK3_Mmus DSISDAAKDVVSKMLHVDPQQRLTAVQVLKHPWIVNRE----------YLSQNQLS----
RSK4_Mmus DNISRGAKDLLSHMLHMDPHQRYTAEQVLKHPWITQRE----------QLPRHQPN----
T01H8.1a_Cele DTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKE----------ALPDRPIQ--SE
RSK1_Spur DNISDRAKDLISRMLHVDPFQRPSTKQVLQHTWFQRID----------LLSETKLK----
RSK2_Spur ------------------------------------------------------------
AqueK025_Aque DTVSAAAKDLVLRMLHVDPQQRCTAAQILQHPWITSRD----------SLPDHKLS----
RSK4_Hsap ---RNDVSHVVKGAMVATYSALTHKT--FQPVLEPVAASSLAQRRSMKKRT-ST------
RSK3_Hsap ---RQDV-HLVKGAMAATYFALNRTP--QAPRLEPVLSSNLAQRRGMKRLT-ST------
RSK2_Hsap ---RQDAPHLVKGAMAATYSALNRN---QSPVLEPVGRSTLAQRRGIKKIT-ST------
RSK1_Hsap ---HQDL-QLVKGAMAATYSALNSSK--PTPQLKPIESSILAQRR-VRKLP-ST------
S6k_Dmel QQQQNHISMALRGAVDATFRAIAIP---QAANVGPVELSMLAKRR-AKDRA-NL------
RSK1_Mmus ---HQDL-QLVKGAMAATYSALNSSK--PTPQLKPIESSILAQRR-VRKLP-ST------
RSK2_Mmus ---RQDAPHLVKGAMAATYSALNRN---QSPVLEPVGRSTLAQRRGIKKIT-ST------
RSK3_Mmus ---RQDV-HLVKGAMAATYFALNRTP--QAPRLEPVLSSSLAQRRGMKRLT-ST------
RSK4_Mmus ---SDEPPQVVIEAVAAPYSVLARNPNRHHPILEPVTASRLAQRRNMKKRT-ST------
T01H8.1a_Cele QVGELD-MQNVKVALEQTYKAIASA---PSVQLRPVGSSALAKRR-MKEILYANYTKNVS
RSK1_Spur ---A---PELVKSAVKATFKALNQAQAE-QGPLEPVTASNLAQRRKLKKLS-ST------
RSK2_Spur ------------------------------------------------------------
AqueK025_Aque ---FKG-T-QIKGALAATFFALNQP---PSAKLEPVSNSSMLQRRKKVESSSSN------
RSK4_Hsap --------------GL
RSK3_Hsap --------------RL
RSK2_Hsap --------------AL
RSK1_Hsap --------------TL
S6k_Dmel --------------HS
RSK1_Mmus --------------TL
RSK2_Mmus --------------AL
RSK3_Mmus --------------RL
RSK4_Mmus --------------GL
T01H8.1a_Cele ANAWCVFFLQCRWLLS
RSK1_Spur --------------TI
RSK2_Spur ---------------P
AqueK025_Aque --------------MS