p38g_Hsap MSSP---------------------------------P----------------------
p38d_Hsap MSLI--------------------------------------------------------
p38b_Hsap MSGP--------------------------------------------------------
p38a_Hsap MSQE--------------------------------------------------------
P38c_Dmel M-----------------------------------------------------------
Mpk2_Dmel MSVS--------------------------------------------------------
p38b_Dmel MSRK--------------------------------------------------------
p38g_Mmus MSSP---------------------------------P----------------------
p38d_Mmus MSLT--------------------------------------------------------
p38b_Mmus MSGP--------------------------------------------------------
p38a_Mmus MSQE--------------------------------------------------------
pmk-3_Cele MASVPSS-SSLPVSHVRRHEDVS---------TPSAPPTKRSNNQSQPPESYEPNTWLQQ
pmk-2_Cele MGMSATMGDS-----------ASIPGVFFADFGPAPPE----------------------
pmk-1_Cele MFPQTTMDH------------------------I-LHP----------------------
HOG1_Scer MTT---------------------------------------------------------
p38_Spur MSAF---------------------------------H----------------------
AqueK129_Aque MAAA--------------------------------DK----------------------
AqueK130_Aque MAAADM-SSV-----------LS---------SPRSPK----------------------
AqueK131_Aque MAKR--------------------------------------------------------
*
p38g_Hsap ------------------------------------------PARSGFYRQEVTKTAWEV
p38d_Hsap -------------------------------------------RKKGFYKQDVNKTAWEL
p38b_Hsap --------------------------------------------RAGFYRQELNKTVWEV
p38a_Hsap --------------------------------------------RPTFYRQELNKTIWEV
P38c_Dmel ---------------------------------------------PEFVRVAINESLWEF
Mpk2_Dmel -------------------------------------------ITKKFYKLDINRTEWEI
p38b_Dmel --------------------------------------------MAKFYKLDINRTEWEI
p38g_Mmus ------------------------------------------PARKGFYRQEVTKTAWEV
p38d_Mmus -------------------------------------------RKRGFYKQDINKTAWEL
p38b_Mmus --------------------------------------------RAGFYRQELNKTVWEV
p38a_Mmus --------------------------------------------RPTFYRQELNKTIWEV
pmk-3_Cele QREQEQQKKLAAENIKKQSIEATGNNEMVGEEEEDILSKPCGPHKRRFQFVMIRNITFAI
pmk-2_Cele ------------------------------------------ITPEGYHEVELNKTKWVL
pmk-1_Cele ------------------------------------------TPREGYYVVELNRSVWVV
HOG1_Scer --------------------------------------------NEEFIRTQIFGTVFEI
p38_Spur ------------------------------------------SLPEDFHHIELNKTIWEV
AqueK129_Aque ------------------------------------------SLKEGFHRIELFKAEWEV
AqueK130_Aque ------------------------------------------PLKPGFYRQDINRDTWIV
AqueK131_Aque -------------------------------------------LPQGYYSSKINGTTWEV
: : : .
p38g_Hsap RAVYR----DLQPVGSGAYGAVCSAV-DG---RTGAKVAIKKLYRPFQSELFAKRAYREL
p38d_Hsap PKTYV----SPTHVGSGAYGSVCSAI-DK---RSGEKVAIKKLSRPFQSEIFAKRAYREL
p38b_Hsap PQRLQ----GLRPVGSGAYGSVCSAY-DA---RLRQKVAVKKLSRPFQSLIHARRTYREL
p38a_Hsap PERYQ----NLSPVGSGAYGSVCAAF-DT---KTGLRVAVKKLSRPFQSIIHAKRTYREL
P38c_Dmel PDIYE----FVRFLGGGSFGQVAKVR-LR---GTENYFAMKRLMRPFEREEDAKGTYREI
Mpk2_Dmel PDIYQ----DLQPVGSGAYGQVSKAV-VR---GTNMHVAIKKLARPFQSAVHAKRTYREL
p38b_Dmel PETYQ----NLQPVGQGAYGQVCKAV-VR---GTSTKVAIKKLARPFQSAVHAKRTYREL
p38g_Mmus RAVYQ----DLQPVGSGAYGAVCSAV-DS---RTGNKVAIKKLYRPFQSELFAKRAYREL
p38d_Mmus PKTYL----APAHVGSGAYGAVCSAI-DK---RTGEKVAIKKLSRPFQSEIFAKRAYREL
p38b_Mmus PQRLQ----GLRPVGSGAYGSVCSAY-DA---RLRQKVAVKKLSRPFQSLIHARRTYREL
p38a_Mmus PERYQ----NLSPVGSGAYGSVCAAF-DT---KTGHRVAVKKLSRPFQSIIHAKRTYREL
pmk-3_Cele PEGYDVEPNSIEYLGGGSFGNVIKTSAVCRDG-LRRYVAIKKMREPFFDPHHARRIFRET
pmk-2_Cele PQWYN----SLKPLGEGAYGVVCTAE-YE---PTGDRVAIKKFFRPFQSTIHAKRTYREL
pmk-1_Cele PNYYI----NLTPIGTGAYGTVCAAE-CT---RSGTRVAIKKFNRPFQSIIHARRTYREL
HOG1_Scer TNRYN----DLNPVGMGAFGLVCSAT-DT---LTSQPVAIKKIMKPFSTAVLAKRTYREL
p38_Spur PNRYV----RLEPVGSGAYGQVCSTE-AEDTRQKGLRVAIKKLSRPFQTVIHAKRTYREL
AqueK129_Aque PLNYR----EIASIGTGAYGTVCSAT-DT---HYNIKVALKKLARPFQNHVHAKRTYREL
AqueK130_Aque KERYQ----DMSPIGIGGFSTVCCAV-DS---ETGEKVALKKLARPFQSPVHAKRAYREI
AqueK131_Aque PDRYQ----ELTPINSGAYGQVCSAL-DT---KYGIRVAIKKLYAPFEHRHNAKKAYREM
:. *.:. * . .*:*:: ** *: :**
p38g_Hsap RLLKHMRH--ENVIGLLDVFTPD---ETLDDFTDFYLVMPFMGTDLGKLMKH------EK
p38d_Hsap LLLKHMQH--ENVIGLLDVFTPA---SSLRNFYDFYLVMPFMQTDLQKIMGM-------E
p38b_Hsap RLLKHLKH--ENVIGLLDVFTPA---TSIEDFSEVYLVTTLMGADLNNIVKC------QA
p38a_Hsap RLLKHMKH--ENVIGLLDVFTPA---RSLEEFNDVYLVTHLMGADLNNIVKC------QK
P38c_Dmel RLLKHMNH--RNVISLLNVFHPP--AHNMMEFQQVYLVTHLMDADLHRYSRS------KR
Mpk2_Dmel RLLKHMDH--ENVIGLLDIFHPHPANGSLENFQQVYLVTHLMDADLNNIIRM------QH
p38b_Dmel RLLKHMDH--ENVIGLLDVFHPGQPADSLDQFQQVYMVTHLMDADLNNIIRT------QK
p38g_Mmus RLLKHMRH--ENVIGLLDVFTPD---ESLDDFTDFYLVMPFMGTDLGKLMKH------ET
p38d_Mmus LLLKHMHH--ENVIGLLDVFTPA---SSLRSFHDFYLVMPFMQTDLQKIMGM-------E
p38b_Mmus RLLKHLKH--ENVIGLLDVFTPA---TSIEDFSEVYLVTTLMGADLNNIVKC------QA
p38a_Mmus RLLKHMKH--ENVIGLLDVFTPA---RSLEEFNDVYLVTHLMGADLNNIVKC------QK
pmk-3_Cele KLLQLMRH--DNIICALDIYTPD---EE-NDFRDVYVVTEFAGRSLYQILKQQRDYGRRV
pmk-2_Cele KLLRTLQH--DNVLEMIDVFTPD---PDASSLNNVYFVSVLMGSDLQNIMKI------QR
pmk-1_Cele RLLRCMCH--ENIIDLLDVFTPN---ENVNDIEDVYFVSMLMGADLSNILKI------QR
HOG1_Scer KLLKHLRH--ENLICLQDIFL--------SPLEDIYFVTELQGTDLHRLLQT------RP
p38_Spur RLLKHMRH--ENVISLLDCFTPD---R--VNFSDVYMVTHLMGADLNNIIKC------QK
AqueK129_Aque RLLKHMKH--ENIIGLLDVFTPA---ENYENFQDVYLVMHLMGSDINNILKQ------QA
AqueK130_Aque KLLKMLTRSNANVVELLDVFTPN---DSLDSFNDIYLVTCFMQSDLDNAIKI------QP
AqueK131_Aque RILSHLKH--ENCIGLLDVFSPC---EDIEEFSDFYMVMHLMSMDLAKLLKENRT--SQI
:* : : * : : : : :.*.* : .: .
p38g_Hsap LGEDRIQFLVYQMLKGLRY-----------------------------IHAAGIIHRDLK
p38d_Hsap FSEEKIQYLVYQMLKGLKY-----------------------------IHSAGVVHRDLK
p38b_Hsap LSDEHVQFLVYQLLRGLKY-----------------------------IHSAGIIHRDLK
p38a_Hsap LTDDHVQFLIYQILRGLKY-----------------------------IHSADIIHRDLK
P38c_Dmel MSDQEIRIILYQILRGLKY-----------------------------IHSAGVVHRDLK
Mpk2_Dmel LSDDHVQFLVYQILRGLKY-----------------------------IHSAGVIHRDLK
p38b_Dmel LSDDHVQFLVYQILRGLKY-----------------------------IHSAGVIHRDLK
p38g_Mmus LSEDRIQFLVYQMLKGLKY-----------------------------IHAAGVIHRDLK
p38d_Mmus FSEDKVQYLVYQMLKGLKY-----------------------------IHSAGIVHRDLK
p38b_Mmus LSDEHVQFLVYQLLRGLKY-----------------------------IHSAGIIHRDLK
p38a_Mmus LTDDHVQFLIYQILRGLKY-----------------------------IHSADIIHRDLK
pmk-3_Cele LTDEHIKFIIYQIIRALKY-----------------------------IHSANIIHRDLK
pmk-2_Cele LTDEQIQLLIYQVLRGLKYMSHQNFNSTIILKKLMHPFQRRNTRFRLYIHSAGIIHRDLK
pmk-1_Cele LNDDHIQFLVYQILRGLKY-----------------------------IHSADIIHRDLK
HOG1_Scer LEKQFVQYFLYQILRGLKY-----------------------------VHSAGVIHRDLK
p38_Spur LSDDHVQFLIYQVLRGLKY-----------------------------IHSAGVIHRDLK
AqueK129_Aque LTDEHVQFLVYQILRGLKY-----------------------------VHSAGIVHRDLK
AqueK130_Aque ITDDQVQLLVYQILRGLKY-----------------------------IHSAGVIHRDIK
AqueK131_Aque LSEDHIKFLLYQILCGLKY-----------------------------VHSAGIIHRDLK
: .: :: ::**:: .*:* :*:*.::***:*
p38g_Hsap PGNLAVNEDCEL-----------------KILDFGLARQ---ADSEMTGYVVTRWYRAPE
p38d_Hsap PGNLAVNEDCEL-----------------KILDFGLARH---ADAEMTGYVVTRWYRAPE
p38b_Hsap PSNVAVNEDCEL-----------------RILDFGLARQ---ADEEMTGYVATRWYRAPE
p38a_Hsap PSNLAVNEDCEL-----------------KILDFGLARH---TDDEMTGYVATRWYRAPE
P38c_Dmel PCNIAVNGNSEV-----------------RILDFGLSRM---CADKMTDHVGTMWYLAPE
Mpk2_Dmel PSNIAVNEDCEL-----------------RILDFGLARP---TENEMTGYVATRWYRAPE
p38b_Dmel PSNIAVNEDCEL-----------------RILDFGLARP---AESEMTGYVATRWYRAPE
p38g_Mmus PGNLAVNEDCEL-----------------KILDFGLARQ---ADSEMTGYVVTRWYRAPE
p38d_Mmus PGNLAVNEDCEL-----------------KILDFGLARH---TDTEMTGYVVTRWYRAPE
p38b_Mmus PSNVAVNEDCEL-----------------RILDFGLARQ---ADEEMTGYVATRWYRAPE
p38a_Mmus PSNLAVNEDCEL-----------------KILDFGLARH---TDDEMTGYVATRWYRAPE
pmk-3_Cele PGNLALTDDSDL-----------------MILDFGLARSLEKKDTSLTQYVQTRWYRSPE
pmk-2_Cele PSNIAVNERCEVKVFLSFSQLSFLILSFFKILDFGLARA---QDAEMTGYVATRWYRAPE
pmk-1_Cele PSNIAVNEDCEL-----------------KILDFGLARQ---TDSEMTGYVATRWYRAPE
HOG1_Scer PSNILINENCDL-----------------KICDFGLARI---QDPQMTGYVSTRYYRAPE
p38_Spur PSNIAVNEDCEL-----------------RILDFGLARS---TDDEMTGYVATRWYRAPE
AqueK129_Aque PSNIAVNEDCEL-----------------RILDFGLARA---TDQEMTGYVATRYWRAPE
AqueK130_Aque PSNIGVSSDLEI-----------------KILDFGLGRK---KKGEMTGYVTTRFWRAPE
AqueK131_Aque PSNIAVNPTCDL-----------------RILDFGLARQ---TDRDMTGYVSTRHYRAPE
* *: :. :: * ****.* .:* :* * : :**
p38g_Hsap VILN-WMRYTQ-TVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMKVTGTPPAEFVQRL
p38d_Hsap VILS-WMHYNQ-TVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGTEFVQKL
p38b_Hsap IMLN-WMHYNQ-TVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKI
p38a_Hsap IMLN-WMHYNQ-TVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVGTPGAELLKKI
P38c_Dmel IIFL-RGQYTK-AIDVWSVGCILAELITDRVLFRGENYVSQIRCLINIMGTPTREFITGI
Mpk2_Dmel IMLN-WMHYDQ-TVDIWSVGCIMAELITRRTLFPGTDHIHQLNLIMEMLGTPPAEFLKKI
p38b_Dmel IMLN-WMHYNQ-TADIWSVGCIMAELLTGRTLFPGTDHIHQLNLIMEVLGTPADEFMSRI
p38g_Mmus VILN-WMRYTQ-TVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMKITGTPPPEFVQKL
p38d_Mmus VILS-WMHYNQ-TVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGAEFVQKL
p38b_Mmus IMLN-WMHYNQ-TVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVGTPSPEVLAKI
p38a_Mmus IMLN-WMHYNQ-TVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTGTPPAYLINRM
pmk-3_Cele VIYWKIDSYTN-LADMWSLGCIAAELLTGEPLFPGDEPNAQYQRITQLCGSPDEELLTKI
pmk-2_Cele IMLN-WMHYTQ-TVDVWSVGCILAELVSGRPLFPGDDHIDQLTKIMSVVGTPKEEFWSKI
pmk-1_Cele IMLN-WMHYTQ-TVDVWSVGCILAELITGKTLFPGSDHIDQLTRIMSVTGTPDEEFLKKI
HOG1_Scer IMLT-WQKYDV-EVDIWSAGCIFAEMIEGKPLFPGKDHVHQFSIITDLLGSPPKDVINTI
p38_Spur IMLN-WMHYTE-KVDIWSVGCIMAELLTQKTLFPGCDHIDQLNKIIAITGKPDETFLQKI
AqueK129_Aque IMLN-WMHYGKEGFDMWSVGCIMAELLTGQVLFPGSDHIDQLTKILQIVGTPDQEFVTKI
AqueK130_Aque VLLQ-WMHYDQ-KVDIWSVGCILAELLTGRVLFFGKNYRDHLNTILQICGTPDEEMMSKI
AqueK131_Aque IMLS-WENYGK-QVDVWSVGCIMAELLGSKVLFPGDNQIDQLHKIFEIMGTPSQSLIDKI
:: * *:** *** **:: . ** * : : : : * * . :
p38g_Hsap QSDE---AKNYMKGLPELEKKDFASILTNASPL--AVNLLEKMLVLDAEQRVTAGEALAH
p38d_Hsap NDKA---AKSYIQSLPQTPRKDFTQLFPRASPQ--AADLLEKMLELDVDKRLTAAQALTH
p38b_Hsap SSEH---ARTYIQSLPPMPQKDLSSIFRGANPL--AIDLLGRMLVLDSDQRVSAAEALAH
p38a_Hsap SSES---ARNYIQSLTQMPKMNFANVFIGANPL--AVDLLEKMLVLDSDKRITAAQALAH
P38c_Dmel SMER---SRNYLEGYPLRQRCDFHHLFMGYDVQ--AIDLMEKMLEMVPEKRITAAEAMLH
Mpk2_Dmel SSES---ARSYIQSLPPMKGRSFKNVFKNANPL--AIDLLEKMLELDAEKRITAEEALSH
p38b_Dmel SSES---ARNYIRSLPVMPRRNFRDIFRGANPL--AIDLLEKMLELDADKRITAEQALAH
p38g_Mmus QSAE---AKNYMEGLPELEKKDFASVLTNASPQ--AVNLLERMLVLDAEQRVTAAEALTH
p38d_Mmus KDKA---AKSYIQSLPQSPKKDFTQLFPRASPQ--AADLLDKMLELDVDKRLTAAQALAH
p38b_Mmus SSEH---ARTYIQSLPPMPQKDLSSVFHGANPL--AIDLLGRMLVLDSDQRVSAAEALAH
p38a_Mmus PSHE---ARNYIQSLAQMPKMNFANVFIGANPL--AVDLLEKMLVLDSDKRITAAQALAH
pmk-3_Cele ENDNSSAIKAVIQSYTTHKRRNFRDVFSAHNPSEDFIDLLEKLLVLDPEKRITVEEAIQH
pmk-2_Cele QSEE---ARNYIKNRSPIIRQDFVTLFPMASPY--ALELLEMMLILDPDRRISVSSALRH
pmk-1_Cele SSEE---ARNYIRNLPKMTRRDFKRLFAQATPQ--AIDLLEKMLHLDPDRRPTAKEAMEH
HOG1_Scer CSEN---TLKFVTSLPHRDPIPFSERFKTVEPD--AVDLLEKMLVFDPKKRITAADALAH
p38_Spur ASES---AKTYLMSMAAYPKRDFSTIFLGASRK--AVDLLEKMLQLDEDRRLSAEQALQH
AqueK129_Aque TSDT---ARSYIESLPKYPKKDFHTFFQGANPL--AIDLLQMLLTIDPDKRITAEQALLH
AqueK130_Aque DSDD---ARTYIRSLPTFAKKNFKEYFTGANPL--AVDLLEKLLHLDPDRRPSAAEALEH
AqueK131_Aque PHQK---TKLYLQSLKVIKPKNLKNLLEIHNND--ALDLLKKLLTLDPERRITVEEALSH
: . : : :*: :* : .:* :. .*: *
p38g_Hsap PYFESLHDTED--EPQVQ-KY-------DDSFDDVDRTLDEWKRVTYKEVL---------
p38d_Hsap PFFEPFRDPEE--ETEAQQPF-------DDSLEHEKLTVDEWKQHIYKEIV---------
p38b_Hsap AYFSQYHDPED--EPEAE-PY-------DESVEAKERTLEEWKELTYQEVL---------
p38a_Hsap AYFAQYHDPDD--EPVAD-PY-------DQSFESRDLLIDEWKSLTYDEVI---------
P38c_Dmel PYLRDLIEPHHHAEDTAP-VY-------DQNFENMVLPVKCWKELVSHEIR---------
Mpk2_Dmel PYLEKYAEPSV--EQTSP-PY-------DHSFEDMDLPVDKWKELIYKEVT---------
p38b_Dmel PYMEKYHDPTD--EQTAA-LY-------DQSFEENELPVEKWREMVFSEVT---------
p38g_Mmus PYFESLRDTED--EPKAQ-KY-------DDSFDDVDRTLEEWKRVTYKEVL---------
p38d_Mmus PFFEPFRDPEE--ETEAQQPF-------DDALEHEKLSVDEWKQHIYKEIS---------
p38b_Mmus AYFSQYHDPDD--EPEAE-PY-------DESVEAKERTLEEWKELTYQEVL---------
p38a_Mmus AYFAQYHDPDD--EPVAD-PY-------DQSFESRDLLIDEWKSLTYDEVI---------
pmk-3_Cele PYLAEFSLPED--EPRAD-HI-------FDLDDSQARTRFEWRDAVWKEIM---------
pmk-2_Cele DYLREYSVPND--EPVAM-DTVINSIVTIDPAEERATTLSDWRELIWNEIR---------
pmk-1_Cele EYLAAYHDETD--EPIAE-EM-------DLNDDVRADTIDEWKKIIWEEIS---------
HOG1_Scer PYSAPYHDPTD--EPVADAKF-------DWHFNDADLPVDTWRVMMYSEIL---------
p38_Spur PYLSKYHDPDD--EPIAA-MF-------DDSQENSDIVIDEWRQRVLKEVT---------
AqueK129_Aque PYMANYSDPDD--EPIAP-PY-------DDSFEKLELDAEGWRKMVWDEIQ---------
AqueK130_Aque PYFSWLHRSDD--EPICDQQY-------TDETEDKDLDTEAWKRETFEDIPVTDLEVTLG
AqueK131_Aque PYLSDYADPVY--ETTAL-PY-------SDDYEELELEASCWKGLVWKQIQ---------
: * : *: ::
p38g_Hsap ------------------------------------------------------------
p38d_Hsap ------------------------------------------------------------
p38b_Hsap ------------------------------------------------------------
p38a_Hsap ------------------------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel ------------------------------------------------------------
p38b_Dmel ------------------------------------------------------------
p38g_Mmus ------------------------------------------------------------
p38d_Mmus ------------------------------------------------------------
p38b_Mmus ------------------------------------------------------------
p38a_Mmus ------------------------------------------------------------
pmk-3_Cele ------------------------------------------------------------
pmk-2_Cele ------------------------------------------------------------
pmk-1_Cele ------------------------------------------------------------
HOG1_Scer ------------------------------------------------------------
p38_Spur ------------------------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque EFLDVSLKALEGDCKITLPETDSDLIDTQDFHVFSVDKSEEFSLSTQLKNISYISTASLK
AqueK131_Aque ------------------------------------------------------------
p38g_Hsap ------------------------------------------------------------
p38d_Hsap ------------------------------------------------------------
p38b_Hsap ------------------------------------------------------------
p38a_Hsap ------------------------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel ------------------------------------------------------------
p38b_Dmel ------------------------------------------------------------
p38g_Mmus ------------------------------------------------------------
p38d_Mmus ------------------------------------------------------------
p38b_Mmus ------------------------------------------------------------
p38a_Mmus ------------------------------------------------------------
pmk-3_Cele ------------------------------------------------------------
pmk-2_Cele ------------------------------------------------------------
pmk-1_Cele ------------------------------------------------------------
HOG1_Scer ------------------------------------------------------------
p38_Spur ------------------------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque DPPTLFLESSIFRSAIEVDIDSRIKRRRETIGSSVKNSAPYPPVRSLSLSSKGMSSEHMI
AqueK131_Aque ------------------------------------------------------------
p38g_Hsap ------------------------------------------------------------
p38d_Hsap ------------------------------------------------------------
p38b_Hsap ------------------------------------------------------------
p38a_Hsap ------------------------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel ------------------------------------------------------------
p38b_Dmel ------------------------------------------------------------
p38g_Mmus ------------------------------------------------------------
p38d_Mmus ------------------------------------------------------------
p38b_Mmus ------------------------------------------------------------
p38a_Mmus ------------------------------------------------------------
pmk-3_Cele ------------------------------------------------------------
pmk-2_Cele ------------------------------------------------------------
pmk-1_Cele ------------------------------------------------------------
HOG1_Scer ------------------------------------------------------------
p38_Spur ------------------------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque FLAGRKEYDNNMSQRMYGSTDVMSLSEGTSSLNLPEESLQRVFSNSMSMIDETGSIQSYG
AqueK131_Aque ------------------------------------------------------------
p38g_Hsap ------------------------------------------------------------
p38d_Hsap ------------------------------------------------------------
p38b_Hsap ------------------------------------------------------------
p38a_Hsap ------------------------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel ------------------------------------------------------------
p38b_Dmel ------------------------------------------------------------
p38g_Mmus ------------------------------------------------------------
p38d_Mmus ------------------------------------------------------------
p38b_Mmus ------------------------------------------------------------
p38a_Mmus ------------------------------------------------------------
pmk-3_Cele ------------------------------------------------------------
pmk-2_Cele ------------------------------------------------------------
pmk-1_Cele ------------------------------------------------------------
HOG1_Scer ------------------------------------------------------------
p38_Spur ------------------------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque SEASEVLSRKLGGKDGLHDSDAFSHGGESSQESEVQHPPRVYIRHSTCDEEQETVVKTSG
AqueK131_Aque ------------------------------------------------------------
p38g_Hsap ------------------------------------------------------------
p38d_Hsap ------------------------------------------------------------
p38b_Hsap ------------------------------------------------------------
p38a_Hsap ------------------------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel ------------------------------------------------------------
p38b_Dmel ------------------------------------------------------------
p38g_Mmus ------------------------------------------------------------
p38d_Mmus ------------------------------------------------------------
p38b_Mmus ------------------------------------------------------------
p38a_Mmus ------------------------------------------------------------
pmk-3_Cele ------------------------------------------------------------
pmk-2_Cele ------------------------------------------------------------
pmk-1_Cele ------------------------------------------------------------
HOG1_Scer ------------------------------------------------------------
p38_Spur ------------------------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque VDDNNLLPTCEENTPPDTPAKQSSALRSRKVKLSSRRASAMATLSPLPVNDDTVLNLPSP
AqueK131_Aque ------------------------------------------------------------
p38g_Hsap ------------------------------------------------------------
p38d_Hsap ------------------------------------------------------------
p38b_Hsap ------------------------------------------------------------
p38a_Hsap ------------------------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel ------------------------------------------------------------
p38b_Dmel ------------------------------------------------------------
p38g_Mmus ------------------------------------------------------------
p38d_Mmus ------------------------------------------------------------
p38b_Mmus ------------------------------------------------------------
p38a_Mmus ------------------------------------------------------------
pmk-3_Cele ------------------------------------------------------------
pmk-2_Cele ------------------------------------------------------------
pmk-1_Cele ------------------------------------------------------------
HOG1_Scer ------------------------------------------------------------
p38_Spur ------------------------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque LLNAQGSFNRTTFRAKRNGSTVISPQHTKVYGSIKLFVVDFDIVVANIILTMDIRGDNTV
AqueK131_Aque ------------------------------------------------------------
p38g_Hsap ------------------------------------------------------------
p38d_Hsap ------------------------------------------------------------
p38b_Hsap ------------------------------------------------------------
p38a_Hsap ------------------------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel ------------------------------------------------------------
p38b_Dmel ------------------------------------------------------------
p38g_Mmus ------------------------------------------------------------
p38d_Mmus ------------------------------------------------------------
p38b_Mmus ------------------------------------------------------------
p38a_Mmus ------------------------------------------------------------
pmk-3_Cele ------------------------------------------------------------
pmk-2_Cele ------------------------------------------------------------
pmk-1_Cele ------------------------------------------------------------
HOG1_Scer ------------------------------------------------------------
p38_Spur ------------------------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque TQIKQSLWRLLRDEGHVTQECDSLWDPEKFTLTYEMNSSVYELYDEQQIFQTTTVAQLWR
AqueK131_Aque ------------------------------------------------------------
p38g_Hsap ------------------------------------------------------------
p38d_Hsap ------------------------------------------------------------
p38b_Hsap ------------------------------------------------------------
p38a_Hsap ------------------------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel ------------------------------------------------------------
p38b_Dmel ------------------------------------------------------------
p38g_Mmus ------------------------------------------------------------
p38d_Mmus ------------------------------------------------------------
p38b_Mmus ------------------------------------------------------------
p38a_Mmus ------------------------------------------------------------
pmk-3_Cele ------------------------------------------------------------
pmk-2_Cele ------------------------------------------------------------
pmk-1_Cele ------------------------------------------------------------
HOG1_Scer ------------------------------------------------------------
p38_Spur ------------------------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque QEKRQKGQLSVVTKRAESKEEKTLNMAISSMIGIGLYQLQFANNDELDITRRKMVAERQK
AqueK131_Aque ------------------------------------------------------------
p38g_Hsap ------------------------------------------------------------
p38d_Hsap ------------------------------------------------------------
p38b_Hsap ------------------------------------------------------------
p38a_Hsap ------------------------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel ------------------------------------------------------------
p38b_Dmel ------------------------------------------------------------
p38g_Mmus ------------------------------------------------------------
p38d_Mmus ------------------------------------------------------------
p38b_Mmus ------------------------------------------------------------
p38a_Mmus ------------------------------------------------------------
pmk-3_Cele ------------------------------------------------------------
pmk-2_Cele ------------------------------------------------------------
pmk-1_Cele ------------------------------------------------------------
HOG1_Scer ------------------------------------------------------------
p38_Spur ------------------------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque AVQQRDPAMYSMEVEVQFTPLPPHVKAMIGEENKLLVKVYYESGASQTFQVDVNTVADDF
AqueK131_Aque ------------------------------------------------------------
p38g_Hsap --------------------------------------------SFKPPRQ---------
p38d_Hsap --------------------------------------------NFSPIAR---------
p38b_Hsap --------------------------------------------SFKPPEP---------
p38a_Hsap --------------------------------------------SFVPPPL---------
P38c_Dmel --------------------------------------------NFRPDQ----------
Mpk2_Dmel --------------------------------------------NFKPPPS---------
p38b_Dmel --------------------------------------------AFKPTAA---------
p38g_Mmus --------------------------------------------SFKPPRQ---------
p38d_Mmus --------------------------------------------NFSPIAR---------
p38b_Mmus --------------------------------------------SFKPLEP---------
p38a_Mmus --------------------------------------------SFVPPPL---------
pmk-3_Cele --------------------------------------------NYKRLSS---------
pmk-2_Cele --------------------------------------------LFQNSAR---------
pmk-1_Cele --------------------------------------------DFQKNVA---------
HOG1_Scer --------------------------------------------DFHKIGG---------
p38_Spur --------------------------------------------EFVADPA---------
AqueK129_Aque --------------------------------------------LFQKDPS---------
AqueK130_Aque LPTVFPTEPHKRKRLGLPEHCNISDYVLKVAGRSSFIHGNFELIDFSPIVKALSKRRDIV
AqueK131_Aque --------------------------------------------TFTPDPA---------
:
p38g_Hsap ------------------------------------------------------------
p38d_Hsap ------------------------------------------------------------
p38b_Hsap ------------------------------------------------------------
p38a_Hsap ------------------------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel ------------------------------------------------------------
p38b_Dmel ------------------------------------------------------------
p38g_Mmus ------------------------------------------------------------
p38d_Mmus ------------------------------------------------------------
p38b_Mmus ------------------------------------------------------------
p38a_Mmus ------------------------------------------------------------
pmk-3_Cele ------------------------------------------------------------
pmk-2_Cele ------------------------------------------------------------
pmk-1_Cele ------------------------------------------------------------
HOG1_Scer ------------------------------------------------------------
p38_Spur ------------------------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque LALVRRSDPKDDLPQHFPDWDLIDESTGLTGTHEELSALGKEHSQVFTMSMWDLQHKFRV
AqueK131_Aque ------------------------------------------------------------
p38g_Hsap ------------------------------------------------------------
p38d_Hsap ------------------------------------------------------------
p38b_Hsap ------------------------------------------------------------
p38a_Hsap ------------------------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel ------------------------------------------------------------
p38b_Dmel ------------------------------------------------------------
p38g_Mmus ------------------------------------------------------------
p38d_Mmus ------------------------------------------------------------
p38b_Mmus ------------------------------------------------------------
p38a_Mmus ------------------------------------------------------------
pmk-3_Cele ------------------------------------------------------------
pmk-2_Cele ------------------------------------------------------------
pmk-1_Cele ------------------------------------------------------------
HOG1_Scer ------------------------------------------------------------
p38_Spur ------------------------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque RILGLDNLRDCSPDFDVIYVDVAVFHGGEELCRTLSTHEITACKYPRWNQWLVFNIAVKN
AqueK131_Aque ------------------------------------------------------------
p38g_Hsap -----------------LGA----------------------------------------
p38d_Hsap -----------------KDS----------------------------------------
p38b_Hsap -----------------PKP----------------------------------------
p38a_Hsap -----------------D------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel -----------------YAQ----------------------------------------
p38b_Dmel -----------------FAE----------------------------------------
p38g_Mmus -----------------LGA----------------------------------------
p38d_Mmus -----------------KDS----------------------------------------
p38b_Mmus -----------------SQL----------------------------------------
p38a_Mmus -----------------D------------------------------------------
pmk-3_Cele -----------------SP-----------------------------------------
pmk-2_Cele -----------------RLSFVS-------------------------------------
pmk-1_Cele -----------------FAD----------------------------------------
HOG1_Scer -----------------SDGQIDISATFDDQVAAATAAAAQAQAQAQAQVQLNMAAHSHN
p38_Spur -----------------P------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque LPKAARLCFAVSGGVRRNDS----------------------------------------
AqueK131_Aque -----------------M------------------------------------------
p38g_Hsap ------------------------------------------------------------
p38d_Hsap ------------------------------------------------------------
p38b_Hsap ------------------------------------------------------------
p38a_Hsap ------------------------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel ------------------------------------------------------------
p38b_Dmel ------------------------------------------------------------
p38g_Mmus ------------------------------------------------------------
p38d_Mmus ------------------------------------------------------------
p38b_Mmus ------------------------------------------------------------
p38a_Mmus ------------------------------------------------------------
pmk-3_Cele ------------------------------------------------------------
pmk-2_Cele ---------------------------------CT-------------------------
pmk-1_Cele ----------------------------------E-------------------------
HOG1_Scer GAGTTGNDHSDIAGGNKVSDHVAANDTITDYGNQA-------------------------
p38_Spur ------------------------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque ----------------------------------RKRSSTWSKKDFVKQNTLRGDNIQAD
AqueK131_Aque ------------------------------------------------------------
p38g_Hsap ------------------------------------------------------------
p38d_Hsap ------------------------------------------------------------
p38b_Hsap ------------------------------------------------------------
p38a_Hsap ------------------------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel ------------------------------------------------------------
p38b_Dmel ------------------------------------------------------------
p38g_Mmus ------------------------------------------------------------
p38d_Mmus ------------------------------------------------------------
p38b_Mmus ------------------------------------------------------------
p38a_Mmus ------------------------------------------------------------
pmk-3_Cele ------------------------------------------------------------
pmk-2_Cele ------------------------------------------------------------
pmk-1_Cele ------------------------------------------------------------
HOG1_Scer ------------------------------------------------------------
p38_Spur ------------------------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque RPLHWVNMQILDHRALLRQGVLRLNLWPYSTSGGEGRWGGMSPVGSTAVNPDGNTAAVLF
AqueK131_Aque ------------------------------------------------------------
p38g_Hsap ------------------------------------------------------------
p38d_Hsap ------------------------------------------------------------
p38b_Hsap ------------------------------------------------------------
p38a_Hsap ------------------------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel ------------------------------------------------------------
p38b_Dmel ------------------------------------------------------------
p38g_Mmus ------------------------------------------------------------
p38d_Mmus ------------------------------------------------------------
p38b_Mmus ------------------------------------------------------------
p38a_Mmus ------------------------------------------------------------
pmk-3_Cele ------------------------------------------------------------
pmk-2_Cele ------------------------------------------------------------
pmk-1_Cele ------------------------------------------------------------
HOG1_Scer ------------------------------------------------------------
p38_Spur ------------------------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque IELDTYLHPVACPTEGWGDEEIRYLRSEMDSPQFSQRFGILLEAFLKGCGKNIFIELQKQ
AqueK131_Aque ------------------------------------------------------------
p38g_Hsap --------------------------------------------R-V-------------
p38d_Hsap --------------------------------------------R-R-------------
p38b_Hsap --------------------------------------------P-G-------------
p38a_Hsap ------------------------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel ------------------------------------------------------------
p38b_Dmel ------------------------------------------------------------
p38g_Mmus --------------------------------------------R-V-------------
p38d_Mmus --------------------------------------------R-R-------------
p38b_Mmus --------------------------------------------P-G-------------
p38a_Mmus ------------------------------------------------------------
pmk-3_Cele --------------------------------------------L-I-------------
pmk-2_Cele --------------------------------------------D-T-------------
pmk-1_Cele --------------------------------------------E-E-------------
HOG1_Scer --------------------------------------------I-Q-------------
p38_Spur ------------------------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque HQAVQDIMSIASGLKKHMEKHKGSATDYAKADLSQQNLPEYFAPPFDPSLRMGNLQVEKC
AqueK131_Aque ------------------------------------------------------------
p38g_Hsap ------------------------------------------------------------
p38d_Hsap ------------------------------------------------------------
p38b_Hsap ------------------------------------------------------------
p38a_Hsap ------------------------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel ------------------------------------------------------------
p38b_Dmel ------------------------------------------------------------
p38g_Mmus ------------------------------------------------------------
p38d_Mmus ------------------------------------------------------------
p38b_Mmus ------------------------------------------------------------
p38a_Mmus ------------------------------------------------------------
pmk-3_Cele ------------------------------------------------------------
pmk-2_Cele ------------------------------------------------------------
pmk-1_Cele ------------------------------------------------------------
HOG1_Scer ------------------------------------------------------------
p38_Spur ------------------------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque RVMDSKKTPLWLEFMNMDPSSTTQKPIKVIAKHGDDLRQDMLTLQMLTIMDSLWQSEGLD
AqueK131_Aque ------------------------------------------------------------
p38g_Hsap ------------------------------------------------------------
p38d_Hsap ------------------------------------------------------------
p38b_Hsap ------------------------------------------------------------
p38a_Hsap ------------------------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel ------------------------------------------------------------
p38b_Dmel ------------------------------------------------------------
p38g_Mmus ------------------------------------------------------------
p38d_Mmus ------------------------------------------------------------
p38b_Mmus ------------------------------------------------------------
p38a_Mmus ------------------------------------------------------------
pmk-3_Cele ------------------------------------------------------------
pmk-2_Cele ------------------------------------------------------------
pmk-1_Cele ------------------------------------------------------------
HOG1_Scer ------------------------------------------------------------
p38_Spur ------------------------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque LYIIPYGCVATGNEMGMIEVVQDAETVAKIQLHHGGSFSTLKDEPLYEWLKKKNPNPKHF
AqueK131_Aque ------------------------------------------------------------
p38g_Hsap ------------------------------------------------------------
p38d_Hsap ------------------------------------------------------------
p38b_Hsap ------------------------------------------------------------
p38a_Hsap ------------------------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel ------------------------------------------------------------
p38b_Dmel ------------------------------------------------------------
p38g_Mmus ------------------------------------------------------------
p38d_Mmus ------------------------------------------------------------
p38b_Mmus ------------------------------------------------------------
p38a_Mmus ------------------------------------------------------------
pmk-3_Cele ------------------------------------------------------------
pmk-2_Cele ------------------------------------------------------------
pmk-1_Cele ------------------------------------------------------------
HOG1_Scer ------------------------------------------------------------
p38_Spur ------------------------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque EQAIERFVYSCAGYCVATYVLGIGDRHNDNIMLTVSGNLFHIDFGHFLGNTKAFLGVNRD
AqueK131_Aque ------------------------------------------------------------
p38g_Hsap ------------------------------------------------------------
p38d_Hsap ------------------------------------------------------------
p38b_Hsap ------------------------------------------------------------
p38a_Hsap ------------------------------------------------------------
P38c_Dmel ------------------------------------------------------------
Mpk2_Dmel ------------------------------------------------------------
p38b_Dmel ------------------------------------------------------------
p38g_Mmus ------------------------------------------------------------
p38d_Mmus ------------------------------------------------------------
p38b_Mmus ------------------------------------------------------------
p38a_Mmus ------------------------------------------------------------
pmk-3_Cele ------------------------------------------------------------
pmk-2_Cele ------------------------------------------------------------
pmk-1_Cele ------------------------------------------------------------
HOG1_Scer ------------------------------------------------------------
p38_Spur ------------------------------------------------------------
AqueK129_Aque ------------------------------------------------------------
AqueK130_Aque RAPFVLTPDFEYVLGKRTSENFKKFEEIAVRAYLIIRKNANLFINLFSMMKCTGIPELRS
AqueK131_Aque ------------------------------------------------------------
p38g_Hsap --------------------------------------------SKETPL
p38d_Hsap --------------------------------------------RSGMKL
p38b_Hsap --------------------------------------------SLEIEQ
p38a_Hsap --------------------------------------------QEEMES
P38c_Dmel ---------------------------------------------LDLHF
Mpk2_Dmel --------------------------------------------VLKDVK
p38b_Dmel --------------------------------------------LLPKEQ
p38g_Mmus --------------------------------------------PKETAL
p38d_Mmus -------------------------------------------RSGMKLQ
p38b_Mmus --------------------------------------------THEIEQ
p38a_Mmus --------------------------------------------QEEMES
pmk-3_Cele --------------------------------------------PGEADR
pmk-2_Cele -------------------------------------------EEEPMKI
pmk-1_Cele -------------------------------------------DEEKMES
HOG1_Scer -------------------------------------------YANEFQQ
p38_Spur ------------------------------------------------MD
AqueK129_Aque -----------------------------------------------LYQ
AqueK130_Aque VEDLDYLKSVLVLGKNEEQAADHFRQQIQKCLRLQWSTQLSWLAHNWVHR
AqueK131_Aque ---------------------------------------------YLLDD