Gene 82699.m00114 (T.vaginalis)

82699.m00114

Species: T.vaginalis
Alias: 82699.m00114, TvagK0987
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
82699.m00114.AA Protein None 230 None Fasta, JSON
82699.m00114.kin_dom Protein Kinase Domain None 182 None Fasta, JSON

Protein domain

Protein domains of 82699.m00114.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 82699.m00114.AA Ciliate-E2 9-197 18 6.6e-28 92.86 In-house 97-365 (365) Show / Hide 
Range on Protein: 9-197
Range on HMM: 97-365/365
Sequence Identity: 18% (53 aa)

IYDAFL--CNNSYNILSKYCRYGDLITYLIKNFDS----------ITYEQRINIAYQMVS---------------AINYIHSRG-IVHFDIKPDNFFIYD
.|..|    .|.. .   || .|||  |...|  .          .| .....| .| ..               |..|.||.. |.| ||||.| ..  
MYECFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF--

IGEDGTPLISIMDFGFSQQIWDS--------------------------------SIPWRTIGTNPYCPPEYFSHSD---------LNMSFDLFSLGVCL
        | | |||.|... |.                                 . ....|| .| .|| ..  .          . . |..||||.|
--------IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL

CVIFTGKYLYLPDCSKSPVSEESLNA--------------------------LTEEAKAVILS----LTPENPEERIS-ADIASQMPLF
    .||. .          ..                              ...|.|  |      .   .||.||. .. . . | |
YEMLFGKPPF----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 82699.m00114.AA Ciliate-E2-Unclassified 25-197 21 1.7e-22 74.86 In-house 102-352 (352) Show / Hide 
Range on Protein: 25-197
Range on HMM: 102-352/352
Sequence Identity: 21% (54 aa)

YCRYGDLITYLIKNFD----------------SITYEQRI-----NIAYQMVSAINYIHSRG-IVHFDIKPDNFFIYDIGEDGTPLISIMDFGFSQ----
||..|||. |. |.                   .| .| .     ....| .....|.|. . |.| ||||.| .. . |.     | | |||.|     
YCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGK--NYYIKIIDFGISKKYQQ

------------QIWDSSIPWRTIGTNPYC----PPEYFSHSDLN----MSFDLFSLGVCLCVIFTGKYLYL-PDCSKSP--------------VSEESL
            |||.. . | ..||. |     .||..     .     . | .||||.|  . .|.| .  ..| ..               . .. .
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

NA---------------LTEEAKAVIL----SLTPENPEERISADIASQMPLF
.                . .|||  |     ..   ||..||... . . |.|
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 82699.m00114.AA Pkinase 9-197 21 3.4e-19 68.94 Pfam 65-293 (293) Show / Hide 
Range on Protein: 9-197
Range on HMM: 65-293/293
Sequence Identity: 21% (49 aa)

IYDAFLCNNSYNILSKYCRYG----DLITYLI-KNFDSI--TYEQRINIAYQMVSAINYIHSRGIVHFDIKPDNFFIYDIGEDGTPLISIMDFGFSQQ--
.||.|  .... .   ||. |    || .|.  ..  ..  .... ....||......|.||.||.| |.||.|..| . |. ..  . | |||.. |  
LYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA-CVKICDFGLAKQFD

IWDSSIPWRTIGTNPYCPPEYFS-HSDLNMSFDLFSLGVCLCVIFTGKYLYLPD------CSKSPVSEESL------NALT-------------------
.  .| ..   || .|..||    ...   . | .|.|. |   ..|. ..  .      . .  . .            .                   
Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHN

--EEAKAVILSLTPENPEERISADIASQMPLF
  ||.| .| ..   .|..|..|. . | | |
WSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 82699.m00114.AA C8 45-139 34 6.9e-19 62.28 In-house 123-226 (226) Show / Hide 
Range on Protein: 45-139
Range on HMM: 123-226/226
Sequence Identity: 34% (36 aa)

EQRINIAYQMVSAINYIHSRGIVHFDIKPDNFFIYDIGEDGTPLISIMDFGFSQQIWDSS--IPWRT---IGTNPYCPPEYFSH-----SDLNMSFDLFS
|.. .|| ||.  .||||.  |.| ||||.|| ..  .. | . | . ||||. |. ..   |  .    .||  |  ||  .       . .   ||||
EMKEIIAIQMIDGVNYIHCKNIMHRDIKPHNFLVCLDQNYG-FEIKLCDFGFASQVSKNKSHIQSKKMNTCGTWAYFAPEIEKKQDNQYKQYRIQSDLFS

LGVCL
.|. |
VGLVL
Kinase 82699.m00114.AA CAMK 25-197 17 3.4e-18 54.55 In-house 141-425 (425) Show / Hide 
Range on Protein: 25-197
Range on HMM: 141-425/425
Sequence Identity: 17% (50 aa)

YCRYG----DLITYLIKNFD--------------SITYEQRINIAYQMVSAINYIHSRGIVHFDIKPDNFFIYDIGED-----------GTPL-ISIMDF
||  |    ||  |.... .               .| ..   .  |..||..|.||..||| |.||.|  . | ..|           .    | | ||
YCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDF

GFSQQIWDSS------------------------IPWRTIGTNPYCP-PEYFSH--------------SDLNMSFDLFSLGVCLCVIFTGKYLYLPD---
||.... ...                          .   || .|.. || ..                  . . |  |.|| | .  .|.. .  |   
GFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDN

---------------------CSKS-P------------------VSEE-SLNALTEEAKAVILSLTPENPEERISADIASQMPLF
                     .  . |                  .|.| .   ...|.|  | ..   .||.|.... . . | .
EICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 82699.m00114.AA Ciliate-C8 45-139 26 1.7e-17 59.47 In-house 119-238 (238) Show / Hide 
Range on Protein: 45-139
Range on HMM: 119-238/238
Sequence Identity: 26% (32 aa)

EQRINIAYQMVSAINYIHSRGIVHFDIKPDNFFIYDIGEDGTPLISIMD------FGFSQQIWDSSI---------PWRT-----IGTNPYCPPEYFSH-
.. ..|| ||   .||.|   |.| ||||.||  ..  ... | | . |      |||. |. ..              .     .|.  |..||     
QMKEIIAIQMIDSVNYLHCFNIMHRDIKPHNFLVCFD-QQYQPTIKLCDFKKQCDFGFASQLPKNKSHYHSKKFKGTDQYIEMYFCGNWGYFAPEVEKKQ

----SDLNM-SFDLFSLGVCL
    ||.     |..|.|..|
SRIQSDIFSKKSDSYSVGLVL
Kinase 82699.m00114.AA TKL 12-146 17 4.2e-15 50.82 In-house 93-286 (364) Show / Hide 
Range on Protein: 12-146
Range on HMM: 93-286/364
Sequence Identity: 17% (36 aa)

AFLCNNS-------------YNILSKYCRYGDLITYLIKNFDSITYEQRINIAYQMVSAINYIHS--------RGIVHFDIKPDNFFIYDIGE-------
. .|...             . |   ||  |.|  ||.        .||...|... ...|| ||        ..|.| |.|..| .. . ..       
YCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMY

----DGTPLISIMDFGFSQ-QIWD-SSIPWR------------------TIGTNPYCPPEYFSHSDLNMSF----------------DLFSLGVCLCVIF
    |... |.  |||.|.   .. ..  .                    .||  ...|| .  .. . .                 | .| |..|. |.
NPNADWCCKIC--DFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEIL

TGK
|..
TRC
Kinase 82699.m00114.AA Ciliate-B1 9-79 33 1.9e-14 47.12 In-house 82-152 (290) Show / Hide 
Range on Protein: 9-79
Range on HMM: 82-152/290
Sequence Identity: 33% (24 aa)

IYDAFLCNNSYNILSKYCRYGDLITYLIKNFDSITYEQRINIAYQMVSAINYIHSRGIVHFDIKPDNFFIY
||| . |. .| | . || .||| .|. ..... | .  .... | ...|.| |...|.| |.||.| .|.
IYDVIQCQQQYYIIMEYCEQGDLYNYIYNCHQNFTHDIVLDFCIQIAKGIQYLHKHKICHRDLKPENILIH
Kinase 82699.m00114.AA Trio 53-101 44 2.6e-14 32.45 In-house 103-150 (258) Show / Hide 
Range on Protein: 53-101
Range on HMM: 103-150/258
Sequence Identity: 44% (22 aa)

QMVSAINYIHSRGIVHFDIKPDNFFIYDIGEDGTPLISIMDFGFSQQIW
||..|..| |. .| | ||||.|  . .    | | | | |||. ||.|
QMLEAVHYLHNCHILHLDIKPENMMMWHYNA-GRPQIKICDFGDAQQLW
S_TKc 82699.m00114.AA S_TKc 1-197 20 3.3e-13 16.85 SMART 1-231 (231) Show / Hide 
Range on Protein: 1-197
Range on HMM: 1-231/231
Sequence Identity: 20% (52 aa)

M--------------------------------------------DSPLVYPIYDAFLCNNSYNILSKYCRY--GDLITYLIKNFDS-----ITYEQRIN
                                             . | .  .||.|   ... .   ||    ||| .|. |.        ..  .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARF

IAYQMVSAINYIHSRGIVHFDIKPDNFFIYDIGEDGTPLISIMDFGFSQQIWDSSIPWRTIGTNPYCPPEYFSHSDLNM-SFDLFSLGVCLCVIFTGKYL
..||...|..|.||.||.| |.||.| .. .        | | |||.. |.         .||  |..|| .     .  . |  |.|..|   ..|. .
YMYQICCALEYCHSHGIIHRDLKPENILLDE-------HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPP

YLPDCSKSPVSEESLNALTEEAKAVILSLTPENPEERISADIASQ-------MPLF
.        . .  .   ..|||  |  .   .||.|..|  | |       .| |
FP---QMQMMFKKIG---SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 82699.m00114.AA CK1-Unclassified 49-78 50 7.4e-13 34.3 In-house 108-137 (244) Show / Hide 
Range on Protein: 49-78
Range on HMM: 108-137/244
Sequence Identity: 50% (15 aa)

NIAYQMVSAINYIHSRGIVHFDIKPDNFFI
.|| ||.. | |.|.....| ||||||| .
MIADQMIQRIEYLHNKNFIHRDIKPDNFLM
Kinase 82699.m00114.AA CK1 48-118 24 1.4e-12 40.32 In-house 135-240 (339) Show / Hide 
Range on Protein: 48-118
Range on HMM: 135-240/339
Sequence Identity: 24% (26 aa)

INIAYQMVSAINYIHSRGIVHFDIKPDNFFIYDIG-----------EDGTPLISIMDFGFSQ-QIWDSS---------------IPWRT-------IG-T
..||.||..|. |.|..|..| ||||||| .   .           ..    . . |||..  .  |..               .| |.       .| |
LMIAIQMLEALEYMHDCGFIHRDIKPDNFCMGRNESFKYGKHHHEWNNEHRQVYMIDFGMARRKYRDKDGHNRWNGPRDKTWQHRPPREHKKKKGFRGCT

NPYCPP
  ||..
ARYCSI
Kinase 82699.m00114.AA Pkinase_Tyr 25-68 25 6e-06 20.75 Pfam 88-134 (270) Show / Hide 
Range on Protein: 25-68
Range on HMM: 88-134/270
Sequence Identity: 25% (12 aa)

YCRYGDLITYLIKN---FDSITYEQRINIAYQMVSAINYIHSRGIVH
|. .||| .|| |.    ...| .. .....|  .. .| .|....|
YMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIH